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Mammalian Phenotype (MP): abnormal erythrocyte morphology

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + 5:   mammalian phenotype [MP:0000001] <29>
+ + + + 4:   hematopoietic system phenotype [MP:0005397] <2>(72|102) (78|63|30)
+ + + 3:   abnormal hematopoietic system morphology/development [MP:0002396] <5>(59|86) (66|47|21)
+ + 2:   abnormal myeloid cell morphology [MP:0013658] <8>(20|41) (26|23|8)
+ + 2:   abnormal hematopoietic cell morphology [MP:0013656] <9>(50|76) (60|43|18)
+ 1:   abnormal blood cell morphology [MP:0013657] <4>(31|49) (37|35|14)
+ 1:   abnormal erythroid lineage cell morphology [MP:0013659] <5>(8|14) (9|12|6)
0:   abnormal erythrocyte morphology [MP:0002447] <30>(6|12) (7|10|4)
- 1:   abnormal erythrocyte cell number [MP:0001586] <3>(1|3) (1|1|0)
- 1:   abnormal erythrocyte ion content [MP:0012372] <3>(0|0) (0|0|0)
- 1:   abnormal hemoglobin [MP:0001588] <3>(2|7) (4|7|3)
- 1:   abnormal erythrocyte magnesium level [MP:0012366] <2>(0|0) (0|0|0)
- 1:   abnormal erythrocyte potassium level [MP:0012369] <2>(0|0) (0|0|0)
- 1:   abnormal erythrocyte sodium level [MP:0012363] <2>(0|0) (0|0|0)
- 1:   abnormal hematocrit [MP:0002596] <2>(3|4) (3|2|1)
- 1:   abnormal mean corpuscular volume [MP:0000226] <2>(1|1) (1|0|0)
- 1:   abnormal nucleated erythrocyte cell number [MP:0012397] <2>(0|0) (0|0|0)
- 1:   abnormal red blood cell distribution width [MP:0010066] <2>(0|0) (0|0|0)
- 1:   abnormal fetal derived definitive erythrocyte morphology [MP:0011240] <1>(0|0) (0|0|0)
- 1:   poikilocytosis [MP:0002643] <1>(0|0) (0|0|0)
- 1:   abnormal erythropoiesis [MP:0000245](0|0) (0|0|0)
- 1:   abnormal red blood cell deformability [MP:0009568](0|0) (0|0|0)
- 1:   acanthocytosis [MP:0010177](0|0) (0|0|0)
- 1:   anisopoikilocytosis [MP:0002641](0|0) (0|0|0)
- 1:   dacryocytosis [MP:0010176](0|0) (0|0|0)
- 1:   echinocytosis [MP:0000256](0|0) (0|0|0)
- 1:   elliptocytosis [MP:0009547](0|0) (0|0|0)
- 1:   hyperchromasia [MP:0002814](0|0) (0|0|0)
- 1:   increased erythrocyte protoporphyrin level [MP:0011188](0|0) (0|0|0)
- 1:   increased number of Heinz bodies [MP:0011171](0|0) (0|0|0)
- 1:   increased number of Howell-Jolly bodies [MP:0010178](0|0) (0|0|0)
- 1:   increased siderocyte number [MP:0010696](0|0) (0|0|0)
- 1:   leptocytosis [MP:0010175](0|0) (0|0|0)
- 1:   macrocytosis [MP:0000248](0|0) (0|0|0)
- 1:   microcytosis [MP:0002813](0|0) (0|0|0)
- 1:   polychromatophilia [MP:0005097](0|0) (0|0|0)
- 1:   spherocytosis [MP:0002812](1|1) (1|0|0)
- 1:   stomatocytosis [MP:0010074](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
AraD/HMP-PK domain-like0.001221Inherited
Cyclin-like0.09186Inherited
Integrin beta tail domain0.2658Inherited
BAR/IMD domain-like0.3133Inherited
Transcription factor STAT-4 N-domain0.5437Inherited
STAT0.5437Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Erythroid transcription factor GATA-10.000211Direct
Noncollagenous (NC1) domain of collagen IV0.0004613Direct
AraD-like aldolase/epimerase0.0007951Direct
Eps15 homology domain (EH domain)0.006308Inherited
Cyclin0.05401Inherited
Hypoxia-inducible factor Hif2a, C-terminal domain0.1456Inherited
Integrin beta EGF-like domains0.2318Inherited
Integrin beta tail domain0.2318Inherited
STAT0.5072Inherited
Transcription factor STAT-4 N-domain0.5072Inherited
STAT DNA-binding domain0.5072Inherited
Short-chain cytokines0.5765Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
AraD/HMP-PK domain-like0.0006735Direct
Cyclin-like0.06885Inherited
Integrin beta tail domain0.2246Inherited
BAR/IMD domain-like0.2695Inherited
Transcription factor STAT-4 N-domain0.4969Inherited
STAT0.4969Inherited
PH domain-like0.8403Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57903,47370
  • 57903 - FYVE/PHD zinc finger
  • 47370 - Bromodomain
  • 0.00541Inherited
    56436,56436
  • 56436 - C-type lectin-like
  • 56436 - C-type lectin-like
  • 0.02855Inherited
    47954,47954
  • 47954 - Cyclin-like
  • 47954 - Cyclin-like
  • 0.05101Inherited
    55785,55785
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.09678Inherited
    47459,55785
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.1659Inherited
    53300,69179
  • 53300 - vWA-like
  • 69179 - Integrin domains
  • 0.2246Inherited
    57196,69687
  • 57196 - EGF/Laminin
  • 69687 - Integrin beta tail domain
  • 0.2246Inherited
    48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 0.4969Inherited
    47655,49417
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.4969Inherited
    49417,55550
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.4969Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    47459,55785,55785
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.09678Inherited
    57196,57196,69687
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 69687 - Integrin beta tail domain
  • 0.2246Inherited
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.4969Inherited
    47655,49417,55550
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.4969Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)