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Mammalian Phenotype (MP): abnormal complement pathway

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   mammalian phenotype [MP:0000001] <29>
+ + + 3:   immune system phenotype [MP:0005387] <2>(76|114) (86|66|35)
+ + 2:   abnormal immune system physiology [MP:0001790] <16>(59|84) (66|49|28)
+ 1:   abnormal humoral immune response [MP:0001800] <4>(10|14) (12|10|8)
+ 1:   abnormal innate immunity [MP:0002419] <5>(17|15) (18|9|5)
0:   abnormal complement pathway [MP:0002471] <6>(2|2) (2|1|1)
- 1:   abnormal complement protein level [MP:0011566] <2>(0|0) (0|0|0)
- 1:   decreased serum complement activity [MP:0012553](0|0) (0|0|0)
- 1:   impaired complement alternative pathway [MP:0002472](0|0) (0|0|0)
- 1:   impaired complement classical pathway [MP:0002473](0|0) (0|0|0)
- 1:   impaired lectin complement pathway [MP:0009062](0|0) (0|0|0)
- 1:   increased serum complement activity [MP:0012554](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Complement control module/SCR domain0.0000005434Direct
Trypsin-like serine proteases0.0003981Direct


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Complement control module/SCR domain0.000000501Direct
Eukaryotic proteases0.0003347Direct


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Complement control module/SCR domain0.0000002194Direct
Trypsin-like serine proteases0.0002076Direct

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.000001038Direct

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57535,57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.000003914Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)