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Mammalian Phenotype (MP): abnormal somatic nervous system morphology

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   mammalian phenotype [MP:0000001] <29>
+ + 2:   nervous system phenotype [MP:0003631] <2>(98|128) (113|79|50)
+ 1:   abnormal nervous system morphology [MP:0003632] <17>(76|104) (91|64|47)
0:   abnormal somatic nervous system morphology [MP:0002752] <7>(34|47) (37|25|14)
- 1:   abnormal cranial nerve morphology [MP:0001056] <12>(6|9) (7|6|2)
- 1:   abnormal cranial ganglia morphology [MP:0001081] <7>(1|3) (4|1|0)
- 1:   abnormal somatic sensory system morphology [MP:0000959] <4>(26|38) (29|19|12)
- 1:   abnormal spinal nerve morphology [MP:0001077] <4>(3|3) (3|1|0)
- 1:   abnormal common peroneal nerve morphology [MP:0011211] <1>(0|0) (0|0|0)
- 1:   abnormal somatic motor system morphology [MP:0001051] <1>(1|3) (1|3|2)
- 1:   abnormal brachial plexus formation [MP:0013915](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Tubby C-terminal domain-like0Direct
Lamin A/C globular tail domain0Direct
Homeodomain-like0.000003855Direct
GDNF receptor-like0.002035Inherited
Growth factor receptor domain0.003782Inherited
EGF/Laminin0.01488Inherited
Nuclear receptor ligand-binding domain0.02486Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.03438Inherited
Sema domain0.0613Inherited
lambda repressor-like DNA-binding domains0.06611Inherited
GAF domain-like0.07138Inherited
Cystine-knot cytokines0.07694Inherited
Intermediate filament protein, coiled coil region0.07887Inherited
Plexin repeat0.08156Inherited
Nicotinic receptor ligand binding domain-like0.09049Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.09049Inherited
Cadherin-like0.1381Inherited
Clc chloride channel0.1658Inherited
Orange domain-like0.1658Inherited
Notch domain0.1658Inherited
HLH, helix-loop-helix DNA-binding domain0.2286Inherited
Integrin domains0.2621Inherited
Family A G protein-coupled receptor-like0.2643Inherited
Frizzled cysteine-rich domain0.2707Inherited
CBS-domain pair0.2711Inherited
HD-domain/PDEase-like0.2842Inherited
Spectrin repeat0.2852Inherited
HMG-box0.3648Inherited
E2F-DP heterodimerization region0.3794Inherited
Second domain of FERM0.3979Inherited
beta-beta-alpha zinc fingers0.666Inherited
Cyclin-like0.7943Inherited
SH3-domain0.8126Inherited
PDZ domain-like0.8304Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Transcriptional factor tubby, C-terminal domain0Direct
Lamin A/C globular tail domain0Direct
Neurotrophin0Direct
Retinoblastoma tumor suppressor domains0Direct
Homeodomain0.0000002303Direct
L domain0.0001722Direct
GDNF receptor-like0.001444Inherited
Rel/Dorsal transcription factors, DNA-binding domain0.002264Inherited
Laminin-type module0.009276Inherited
Adenylyl and guanylyl cyclase catalytic domain0.01579Inherited
Nuclear receptor ligand-binding domain0.02026Inherited
Nuclear receptor0.02026Inherited
NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain0.04058Inherited
Paired domain0.04058Inherited
POU-specific domain0.04847Inherited
Growth factor receptor domain0.05108Inherited
Sema domain0.05108Inherited
GAF domain0.05678Inherited
Plexin repeat0.06978Inherited
Intermediate filament protein, coiled coil region0.07379Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.07703Inherited
Nicotinic receptor ligand binding domain-like0.07703Inherited
Extracellular domain of cell surface receptors0.07703Inherited
EGF-type module0.07806Inherited
DIX domain0.1416Inherited
Notch domain0.1416Inherited
Hairy Orange domain0.1416Inherited
Clc chloride channel0.1416Inherited
cAMP-binding domain0.1449Inherited
DEP domain0.1467Inherited
Cadherin0.175Inherited
Calmodulin-like0.1759Inherited
Rhodopsin-like0.2125Inherited
PDEase0.2167Inherited
HLH, helix-loop-helix DNA-binding domain0.2171Inherited
Spectrin repeat0.2287Inherited
E2F dimerization segment0.2427Inherited
CBS-domain pair0.2427Inherited
Frizzled cysteine-rich domain0.2471Inherited
Integrin domains0.2498Inherited
HMG-box0.3409Inherited
Cell cycle transcription factor e2f-dp0.351Inherited
EF-hand modules in multidomain proteins0.4557Inherited
PDZ domain0.4855Inherited
Classic zinc finger, C2H20.5147Inherited
Motor proteins0.5734Inherited
SH3-domain0.8094Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Tubby C-terminal domain-like0Direct
Lamin A/C globular tail domain0Direct
Homeodomain-like0.000001644Direct
GDNF receptor-like0.001158Inherited
Growth factor receptor domain0.002219Inherited
EGF/Laminin0.009546Inherited
Nucleotide cyclase0.01214Inherited
Nuclear receptor ligand-binding domain0.01661Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.02361Inherited
Sema domain0.04423Inherited
lambda repressor-like DNA-binding domains0.04807Inherited
GAF domain-like0.05228Inherited
Cystine-knot cytokines0.05663Inherited
Intermediate filament protein, coiled coil region0.05815Inherited
Plexin repeat0.06032Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.06761Inherited
Nicotinic receptor ligand binding domain-like0.06761Inherited
Cadherin-like0.1083Inherited
Orange domain-like0.1325Inherited
Clc chloride channel0.1325Inherited
Notch domain0.1325Inherited
L domain-like0.1621Inherited
HLH, helix-loop-helix DNA-binding domain0.1898Inherited
Integrin domains0.2209Inherited
Family A G protein-coupled receptor-like0.223Inherited
Frizzled cysteine-rich domain0.2291Inherited
CBS-domain pair0.2294Inherited
HD-domain/PDEase-like0.2418Inherited
Spectrin repeat0.2428Inherited
HMG-box0.3191Inherited
E2F-DP heterodimerization region0.3332Inherited
Second domain of FERM0.3513Inherited
beta-beta-alpha zinc fingers0.6235Inherited
"Winged helix" DNA-binding domain0.7167Inherited
Cyclin-like0.7592Inherited
SH3-domain0.7785Inherited
PDZ domain-like0.7978Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
64593,74853
  • 64593 - Intermediate filament protein, coiled coil region
  • 74853 - Lamin A/C globular tail domain
  • 0Direct
    52058,57184
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.0001255Direct
    57184,52058
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.0001255Direct
    49417,81296
  • 49417 - p53-like transcription factors
  • 81296 - E set domains
  • 0.00172Inherited
    56112,55073
  • 56112 - Protein kinase-like (PK-like)
  • 55073 - Nucleotide cyclase
  • 0.001927Inherited
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.005405Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.02153Inherited
    101912,103575
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 0.04423Inherited
    47413,46689
  • 47413 - lambda repressor-like DNA-binding domains
  • 46689 - Homeodomain-like
  • 0.04681Inherited
    57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.04681Inherited
    55781,55781
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 0.05228Inherited
    55781,109604
  • 55781 - GAF domain-like
  • 109604 - HD-domain/PDEase-like
  • 0.05228Inherited
    57184,49265
  • 57184 - Growth factor receptor domain
  • 49265 - Fibronectin type III
  • 0.05228Inherited
    63712,90112
  • 63712 - Nicotinic receptor ligand binding domain-like
  • 90112 - Neurotransmitter-gated ion-channel transmembrane pore
  • 0.06761Inherited
    52058,48726
  • 52058 - L domain-like
  • 48726 - Immunoglobulin
  • 0.07058Inherited
    81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 0.0802Inherited
    57184,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.0802Inherited
    47473,57850
  • 47473 - EF-hand
  • 57850 - RING/U-box
  • 0.1325Inherited
    47459,158457
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 158457 - Orange domain-like
  • 0.1325Inherited
    49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.2291Inherited
    46785,144074
  • 46785 - "Winged helix" DNA-binding domain
  • 144074 - E2F-DP heterodimerization region
  • 0.3332Inherited
    46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.3899Inherited
    50156,50156
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 0.5286Inherited
    47473,47473
  • 47473 - EF-hand
  • 47473 - EF-hand
  • 0.5323Inherited
    57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 0.5712Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    52058,48726,48726
  • 52058 - L domain-like
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0Direct
    57184,52058,57184
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0Direct
    52058,57184,52058
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.0001255Direct
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.0006755Direct
    57184,49899,49899
  • 57184 - Growth factor receptor domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.02416Inherited
    57184,57196,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.03652Inherited
    55781,55781,109604
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 109604 - HD-domain/PDEase-like
  • 0.05228Inherited
    57196,57184,57196
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.07058Inherited
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.0802Inherited
    81296,81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 81296 - E set domains
  • 0.0802Inherited
    49313,49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.1221Inherited
    47473,47473,57850
  • 47473 - EF-hand
  • 47473 - EF-hand
  • 57850 - RING/U-box
  • 0.1325Inherited
    49899,57196,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.1362Inherited
    46966,46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.2742Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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