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Mammalian Phenotype (MP): nervous system phenotype

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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ 1:   mammalian phenotype [MP:0000001] <29>
0:   nervous system phenotype [MP:0003631] <2>(98|127) (112|79|50)
- 1:   abnormal nervous system physiology [MP:0003633] <38>(43|59) (51|31|18)
- 1:   abnormal nervous system morphology [MP:0003632] <17>(76|104) (91|64|47)


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Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Composite domain of metallo-dependent hydrolases0Direct
Lamin A/C globular tail domain0Direct
Nitric oxide (NO) synthase oxygenase domain0Direct
Synuclein0Direct
Tubby C-terminal domain-like0Direct
Hedgehog/DD-peptidase0Direct
Oligoxyloglucan reducing end-specific cellobiohydrolase0Direct
E2F-DP heterodimerization region0Direct
Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain0Direct
Proton glutamate symport protein0Direct
Metallothionein0Direct
Hedgehog/intein (Hint) domain0Direct
Notch domain0Direct
Homeodomain-like0.0000000000005343Direct
Neurotransmitter-gated ion-channel transmembrane pore0.0000000003581Direct
Nicotinic receptor ligand binding domain-like0.0000000003581Direct
Periplasmic binding protein-like I0.00000002852Direct
PDZ domain-like0.000003413Direct
HLH, helix-loop-helix DNA-binding domain0.00002446Direct
Voltage-gated potassium channels0.00003897Direct
Spectrin repeat0.0001249Direct
Periplasmic binding protein-like II0.000126Direct
Nuclear receptor ligand-binding domain0.0002273Direct
NHL repeat0.0003397Direct
Sema domain0.0003672Direct
Frizzled cysteine-rich domain0.0005285Direct
Plexin repeat0.0005588Direct
Galactose-binding domain-like0.001582Inherited
L27 domain0.001744Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.005399Inherited
Family A G protein-coupled receptor-like0.006347Inherited
Fibronectin type III0.007539Inherited
Orange domain-like0.00832Inherited
Caspase-like0.01071Inherited
YWTD domain0.01318Inherited
GAF domain-like0.0175Inherited
EGF/Laminin0.02281Inherited
Concanavalin A-like lectins/glucanases0.02392Inherited
C2 domain (Calcium/lipid-binding domain, CaLB)0.0247Inherited
p53-like transcription factors0.02697Inherited
SMAD MH1 domain0.02865Inherited
SNF-like0.04278Inherited
Cupredoxins0.04278Inherited
SH3-domain0.05315Inherited
HCP-like0.05368Inherited
Doublecortin (DC)0.05368Inherited
Metallo-dependent hydrolases0.06745Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.06745Inherited
Riboflavin synthase domain-like0.06745Inherited
HMA, heavy metal-associated domain0.0733Inherited
SRF-like0.0733Inherited
GDNF receptor-like0.0733Inherited
Growth factor receptor domain0.08638Inherited
lambda repressor-like DNA-binding domains0.08695Inherited
GTPase activation domain, GAP0.1001Inherited
Heat shock protein 70kD (HSP70), C-terminal subdomain0.1066Inherited
Clc chloride channel0.1066Inherited
Bcl-2 inhibitors of programmed cell death0.1096Inherited
TIMP-like0.1295Inherited
cAMP-binding domain-like0.1608Inherited
PH domain-like0.1611Inherited
Cysteine-rich domain0.1667Inherited
Kringle-like0.1679Inherited
Cystine-knot cytokines0.1683Inherited
Cap-Gly domain0.1747Inherited
Flavoproteins0.1747Inherited
Cadherin-like0.1898Inherited
SNARE fusion complex0.1911Inherited
L domain-like0.1957Inherited
4-helical cytokines0.237Inherited
Cyclin-like0.2389Inherited
Zn-dependent exopeptidases0.26Inherited
Immunoglobulin0.2601Inherited
Formate/glycerate dehydrogenase catalytic domain-like0.2765Inherited
CBS-domain pair0.3014Inherited
Second domain of FERM0.3119Inherited
Integrin domains0.4386Inherited
SAM/Pointed domain0.4814Inherited
Spermadhesin, CUB domain0.4874Inherited
PLP-dependent transferases0.5056Inherited
MFS general substrate transporter0.5267Inherited
BAR/IMD domain-like0.531Inherited
HD-domain/PDEase-like0.5444Inherited
HMG-box0.6037Inherited
TNF receptor-like0.6054Inherited
Toll/Interleukin receptor TIR domain0.6215Inherited
Bromodomain0.6471Inherited
PreATP-grasp domain0.6707Inherited
Intermediate filament protein, coiled coil region0.7143Inherited
Complement control module/SCR domain0.7399Inherited
FAD/NAD(P)-binding domain0.7729Inherited
ABC transporter transmembrane region0.8399Inherited
Glutathione synthetase ATP-binding domain-like0.8773Inherited
SAP domain0.8902Inherited
beta-beta-alpha zinc fingers0.9352Inherited
alpha/beta-Hydrolases0.9746Inherited
Cysteine proteinases1Inherited
RNA-binding domain, RBD1Inherited


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Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Transcriptional factor tubby, C-terminal domain0Direct
E2F dimerization segment0Direct
Synapsin domain0Direct
Synapsin C-terminal domain0Direct
Notch domain0Direct
Hedgehog C-terminal (Hog) autoprocessing domain0Direct
Neurotrophin0Direct
Lamin A/C globular tail domain0Direct
Nitric oxide (NO) synthase oxygenase domain0Direct
Proton glutamate symport protein0Direct
Retinoblastoma tumor suppressor domains0Direct
Hydantoinase (dihydropyrimidinase)0Direct
Metallothionein0Direct
Oligoxyloglucan reducing end-specific cellobiohydrolase0Direct
Hedgehog (development protein), N-terminal signaling domain0Direct
Synuclein0Direct
Cytochrome p450 reductase N-terminal domain-like0Direct
Other IPT/TIG domains0Direct
Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain0Direct
Hydantoinase (dihydropyrimidinase), catalytic domain0Direct
Homeodomain0.000000000001258Direct
Nicotinic receptor ligand binding domain-like0.0000000003954Direct
Neurotransmitter-gated ion-channel transmembrane pore0.0000000003954Direct
L-arabinose binding protein-like0.0000006752Direct
Laminin G-like module0.000001338Direct
Phosphate binding protein-like0.000004976Direct
PDZ domain0.00002288Direct
HLH, helix-loop-helix DNA-binding domain0.00003278Direct
Nuclear receptor0.00006351Direct
Nuclear receptor ligand-binding domain0.0002229Direct
Sema domain0.0003204Direct
Frizzled cysteine-rich domain0.000425Direct
Plexin repeat0.0005129Direct
Spectrin repeat0.0007517Direct
Laminin-type module0.0008397Direct
L27 domain0.001302Inherited
Hypoxia-inducible factor Hif2a, C-terminal domain0.002293Inherited
Caspase catalytic domain0.002918Inherited
DEP domain0.002918Inherited
Rhodopsin-like0.00338Inherited
Voltage-gated potassium channels0.004619Inherited
Ephrin ectodomain0.006393Inherited
Hairy Orange domain0.006393Inherited
Fibronectin type III0.01001Inherited
YWTD domain0.01095Inherited
Cell cycle transcription factor e2f-dp0.01196Inherited
Paired domain0.01196Inherited
DIX domain0.01377Inherited
GAF domain0.01377Inherited
I set domains0.0159Inherited
LDL receptor-like module0.02308Inherited
SMAD domain0.02336Inherited
SMAD MH1 domain0.02336Inherited
NADPH-cytochrome p450 reductase-like0.02903Inherited
NADPH-cytochrome p450 reductase FAD-binding domain-like0.02903Inherited
Extracellular domain of cell surface receptors0.02979Inherited
Enabled/VASP homology 1 domain (EVH1 domain)0.02979Inherited
SNF-like0.03691Inherited
cAMP-binding domain0.0373Inherited
L domain0.04456Inherited
Doublecortin (DC)0.04456Inherited
Multidrug efflux transporter AcrB transmembrane domain0.06075Inherited
SRF-like0.06075Inherited
Formate/glycerate dehydrogenases, substrate-binding domain0.06075Inherited
beta-glycanases0.06075Inherited
GDNF receptor-like0.06075Inherited
Mib/herc2 domain0.06075Inherited
HMA, heavy metal-associated domain0.06075Inherited
SH3-domain0.06525Inherited
Pyridoxal-dependent decarboxylase0.0832Inherited
Heat shock protein 70kD (HSP70), C-terminal subdomain0.09325Inherited
Clc chloride channel0.09325Inherited
Ephrin receptor ligand binding domain0.09689Inherited
NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain0.09689Inherited
Bcl-2 inhibitors of programmed cell death0.09735Inherited
Rel/Dorsal transcription factors, DNA-binding domain0.09735Inherited
Forkhead DNA-binding domain0.1042Inherited
Ngr ectodomain-like0.119Inherited
EGF-type module0.1265Inherited
Phosphotyrosine-binding domain (PTB)0.1293Inherited
POU-specific domain0.134Inherited
EF-hand modules in multidomain proteins0.134Inherited
Cap-Gly domain0.1569Inherited
Calmodulin-like0.1666Inherited
Tetramerization domain of potassium channels0.1802Inherited
SNARE fusion complex0.1802Inherited
Cadherin0.2013Inherited
Long-chain cytokines0.2041Inherited
Motor proteins0.2075Inherited
Protein kinase cysteine-rich domain (cys2, phorbol-binding domain)0.2147Inherited
CBS-domain pair0.2168Inherited
Synaptotagmin-like (S variant)0.2289Inherited
Fibronectin type II module0.2299Inherited
Adenylyl and guanylyl cyclase catalytic domain0.2316Inherited
SAM (sterile alpha motif) domain0.2366Inherited
Formate/glycerate dehydrogenases, NAD-domain0.2553Inherited
Leucine zipper domain0.2818Inherited
Transforming growth factor (TGF)-beta0.2933Inherited
Acetylcholinesterase-like0.3103Inherited
PLC-like (P variant)0.3127Inherited
FYVE, a phosphatidylinositol-3-phosphate binding domain0.3616Inherited
Cyclin0.3726Inherited
Growth factor receptor domain0.3928Inherited
Cytoplasmic domain of inward rectifier potassium channel0.3932Inherited
PDEase0.4033Inherited
p120GAP domain-like0.4297Inherited
Integrin domains0.4352Inherited
C1 set domains (antibody constant domain-like)0.4374Inherited
Integrin alpha N-terminal domain0.4374Inherited
Actin/HSP700.4374Inherited
Spermadhesin, CUB domain0.4954Inherited
TNF receptor-like0.5101Inherited
HMG-box0.6123Inherited
Bromodomain0.6492Inherited
G proteins0.6856Inherited
BAR domain0.6893Inherited
Toll/Interleukin receptor TIR domain0.7116Inherited
Intermediate filament protein, coiled coil region0.7221Inherited
Complement control module/SCR domain0.7451Inherited
ABC transporter transmembrane region0.839Inherited
SAP domain0.8853Inherited
MAM domain0.8853Inherited
Classic zinc finger, C2H20.899Inherited
SH2 domain0.9008Inherited
ABC transporter ATPase domain-like0.9143Inherited
Canonical RBD0.9689Inherited
V set domains (antibody variable domain-like)1Inherited


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Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
E2F-DP heterodimerization region0Direct
Metallothionein0Direct
Proton glutamate symport protein0Direct
Hedgehog/DD-peptidase0Direct
Tubby C-terminal domain-like0Direct
Nitric oxide (NO) synthase oxygenase domain0Direct
Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain0Direct
Notch domain0Direct
Composite domain of metallo-dependent hydrolases0Direct
Lamin A/C globular tail domain0Direct
Synuclein0Direct
Oligoxyloglucan reducing end-specific cellobiohydrolase0Direct
Hedgehog/intein (Hint) domain0Direct
Homeodomain-like0.0000000000001937Direct
Nicotinic receptor ligand binding domain-like0.0000000001318Direct
Neurotransmitter-gated ion-channel transmembrane pore0.0000000001318Direct
Periplasmic binding protein-like I0.00000001093Direct
PDZ domain-like0.000001449Direct
HLH, helix-loop-helix DNA-binding domain0.00001112Direct
Voltage-gated potassium channels0.00001806Direct
Spectrin repeat0.00006151Direct
Periplasmic binding protein-like II0.00006205Direct
Nuclear receptor ligand-binding domain0.0001155Direct
NHL repeat0.0001767Direct
Sema domain0.0001912Direct
Frizzled cysteine-rich domain0.0002799Direct
Plexin repeat0.0002969Direct
Galactose-binding domain-like0.0008876Direct
L27 domain0.0009848Direct
Glucocorticoid receptor-like (DNA-binding domain)0.003247Inherited
Family A G protein-coupled receptor-like0.003862Inherited
Fibronectin type III0.004627Inherited
Orange domain-like0.005142Inherited
Caspase-like0.006733Inherited
YWTD domain0.008403Inherited
GAF domain-like0.01141Inherited
EGF/Laminin0.01515Inherited
Concanavalin A-like lectins/glucanases0.01594Inherited
C2 domain (Calcium/lipid-binding domain, CaLB)0.01652Inherited
LDL receptor-like module0.01655Inherited
p53-like transcription factors0.01816Inherited
SMAD MH1 domain0.01941Inherited
SNF-like0.02989Inherited
Cupredoxins0.02989Inherited
SH3-domain0.03776Inherited
Doublecortin (DC)0.03816Inherited
HCP-like0.03816Inherited
E set domains0.04258Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.04918Inherited
Riboflavin synthase domain-like0.04918Inherited
Metallo-dependent hydrolases0.04918Inherited
HMA, heavy metal-associated domain0.05384Inherited
SRF-like0.05384Inherited
GDNF receptor-like0.05384Inherited
Mib/herc2 domain-like0.05384Inherited
Growth factor receptor domain0.06432Inherited
lambda repressor-like DNA-binding domains0.06477Inherited
Glutamine synthetase/guanido kinase0.07313Inherited
GTPase activation domain, GAP0.0756Inherited
Multidrug efflux transporter AcrB transmembrane domain0.0811Inherited
Clc chloride channel0.0811Inherited
Heat shock protein 70kD (HSP70), C-terminal subdomain0.0811Inherited
Bcl-2 inhibitors of programmed cell death0.08378Inherited
TIMP-like0.1007Inherited
cAMP-binding domain-like0.1282Inherited
PH domain-like0.1285Inherited
Cysteine-rich domain0.1333Inherited
Kringle-like0.1344Inherited
Cystine-knot cytokines0.1346Inherited
Cap-Gly domain0.1405Inherited
Flavoproteins0.1405Inherited
Cadherin-like0.1541Inherited
SNARE fusion complex0.1553Inherited
L domain-like0.1596Inherited
BRCT domain0.1727Inherited
4-helical cytokines0.1978Inherited
Cyclin-like0.1995Inherited
Nucleotide cyclase0.2022Inherited
Zn-dependent exopeptidases0.2191Inherited
Immunoglobulin0.2192Inherited
Leucine zipper domain0.2333Inherited
Formate/glycerate dehydrogenase catalytic domain-like0.2347Inherited
CBS-domain pair0.2582Inherited
Second domain of FERM0.2681Inherited
"Winged helix" DNA-binding domain0.3032Inherited
ARM repeat0.3243Inherited
Quinoprotein alcohol dehydrogenase-like0.3288Inherited
Integrin domains0.3911Inherited
TPR-like0.4029Inherited
Integrin alpha N-terminal domain0.4232Inherited
SAM/Pointed domain0.4338Inherited
Spermadhesin, CUB domain0.4399Inherited
PLP-dependent transferases0.458Inherited
MFS general substrate transporter0.4795Inherited
BAR/IMD domain-like0.484Inherited
HD-domain/PDEase-like0.4976Inherited
HMG-box0.5583Inherited
TNF receptor-like0.5601Inherited
Toll/Interleukin receptor TIR domain0.5768Inherited
Bromodomain0.6037Inherited
PreATP-grasp domain0.6285Inherited
Intermediate filament protein, coiled coil region0.6744Inherited
Complement control module/SCR domain0.7013Inherited
FAD/NAD(P)-binding domain0.736Inherited
ABC transporter transmembrane region0.8081Inherited
Glutathione synthetase ATP-binding domain-like0.8486Inherited
SH2 domain0.8524Inherited
SAP domain0.8625Inherited
beta-beta-alpha zinc fingers0.9119Inherited
alpha/beta-Hydrolases0.9566Inherited
RNA-binding domain, RBD0.992Inherited
Cysteine proteinases1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57196,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0Direct
    56496,49899
  • 56496 - Fibrinogen C-terminal domain-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    81324,53850
  • 81324 - Voltage-gated potassium channels
  • 53850 - Periplasmic binding protein-like II
  • 0Direct
    57184,49899
  • 57184 - Growth factor receptor domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    50729,50156
  • 50729 - PH domain-like
  • 50156 - PDZ domain-like
  • 0Direct
    51338,51556
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 51556 - Metallo-dependent hydrolases
  • 0Direct
    51556,51338
  • 51556 - Metallo-dependent hydrolases
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 0Direct
    48726,82895
  • 48726 - Immunoglobulin
  • 82895 - TSP-1 type 1 repeat
  • 0Direct
    57196,57424
  • 57196 - EGF/Laminin
  • 57424 - LDL receptor-like module
  • 0Direct
    81296,101898
  • 81296 - E set domains
  • 101898 - NHL repeat
  • 0Direct
    47473,57850
  • 47473 - EF-hand
  • 57850 - RING/U-box
  • 0Direct
    50044,50156
  • 50044 - SH3-domain
  • 50156 - PDZ domain-like
  • 0Direct
    90193,90193
  • 90193 - Notch domain
  • 90193 - Notch domain
  • 0Direct
    46785,144074
  • 46785 - "Winged helix" DNA-binding domain
  • 144074 - E2F-DP heterodimerization region
  • 0Direct
    57196,56496
  • 57196 - EGF/Laminin
  • 56496 - Fibrinogen C-terminal domain-like
  • 0Direct
    49562,51045
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 51045 - WW domain
  • 0Direct
    50729,57889
  • 50729 - PH domain-like
  • 57889 - Cysteine-rich domain
  • 0Direct
    101288,50156
  • 101288 - L27 domain
  • 50156 - PDZ domain-like
  • 0Direct
    64593,74853
  • 64593 - Intermediate filament protein, coiled coil region
  • 74853 - Lamin A/C globular tail domain
  • 0Direct
    46966,51045
  • 46966 - Spectrin repeat
  • 51045 - WW domain
  • 0Direct
    55166,51294
  • 55166 - Hedgehog/DD-peptidase
  • 51294 - Hedgehog/intein (Hint) domain
  • 0Direct
    49785,49899
  • 49785 - Galactose-binding domain-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    51045,47473
  • 51045 - WW domain
  • 47473 - EF-hand
  • 0Direct
    63712,90112
  • 63712 - Nicotinic receptor ligand binding domain-like
  • 90112 - Neurotransmitter-gated ion-channel transmembrane pore
  • 0.0000000001318Direct
    49899,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 0.00001158Direct
    49899,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.0001592Direct
    101912,103575
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 0.0001912Direct
    50156,50156
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 0.0001912Direct
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.0002219Direct
    46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.0002799Direct
    63825,57196
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 0.0009848Direct
    57424,57184
  • 57424 - LDL receptor-like module
  • 57184 - Growth factor receptor domain
  • 0.005142Inherited
    47459,158457
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 158457 - Orange domain-like
  • 0.005142Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.00613Inherited
    57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.009631Inherited
    47986,52129
  • 47986 - DEATH domain
  • 52129 - Caspase-like
  • 0.01141Inherited
    55781,55781
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 0.01141Inherited
    53822,53850
  • 53822 - Periplasmic binding protein-like I
  • 53850 - Periplasmic binding protein-like II
  • 0.01141Inherited
    57196,63825
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 0.01141Inherited
    55781,109604
  • 55781 - GAF domain-like
  • 109604 - HD-domain/PDEase-like
  • 0.01141Inherited
    47473,47473
  • 47473 - EF-hand
  • 47473 - EF-hand
  • 0.01716Inherited
    57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.01941Inherited
    57184,49265
  • 57184 - Growth factor receptor domain
  • 49265 - Fibronectin type III
  • 0.02512Inherited
    63501,50242
  • 63501 - Frizzled cysteine-rich domain
  • 50242 - TIMP-like
  • 0.02512Inherited
    81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 0.0311Inherited
    57184,52058
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.03816Inherited
    52058,57184
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.03816Inherited
    57184,63825
  • 57184 - Growth factor receptor domain
  • 63825 - YWTD domain
  • 0.03816Inherited
    57196,49899
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.03816Inherited
    89837,89837
  • 89837 - Doublecortin (DC)
  • 89837 - Doublecortin (DC)
  • 0.03816Inherited
    57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.04897Inherited
    103575,48726
  • 103575 - Plexin repeat
  • 48726 - Immunoglobulin
  • 0.04918Inherited
    57535,49854
  • 57535 - Complement control module/SCR domain
  • 49854 - Spermadhesin, CUB domain
  • 0.05384Inherited
    48452,81901
  • 48452 - TPR-like
  • 81901 - HCP-like
  • 0.05384Inherited
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.05777Inherited
    47413,46689
  • 47413 - lambda repressor-like DNA-binding domains
  • 46689 - Homeodomain-like
  • 0.072Inherited
    50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0.072Inherited
    81324,81324
  • 81324 - Voltage-gated potassium channels
  • 81324 - Voltage-gated potassium channels
  • 0.0811Inherited
    56112,47769
  • 56112 - Protein kinase-like (PK-like)
  • 47769 - SAM/Pointed domain
  • 0.08161Inherited
    49417,81296
  • 49417 - p53-like transcription factors
  • 81296 - E set domains
  • 0.08378Inherited
    49562,48350
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48350 - GTPase activation domain, GAP
  • 0.1405Inherited
    56112,55073
  • 56112 - Protein kinase-like (PK-like)
  • 55073 - Nucleotide cyclase
  • 0.1405Inherited
    52058,48726
  • 52058 - L domain-like
  • 48726 - Immunoglobulin
  • 0.1929Inherited
    49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.2127Inherited
    57184,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.2157Inherited
    52283,51735
  • 52283 - Formate/glycerate dehydrogenase catalytic domain-like
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0.2347Inherited
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.3352Inherited
    49854,57535
  • 49854 - Spermadhesin, CUB domain
  • 57535 - Complement control module/SCR domain
  • 0.3399Inherited
    57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.3609Inherited
    81324,81296
  • 81324 - Voltage-gated potassium channels
  • 81296 - E set domains
  • 0.3609Inherited
    57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.3706Inherited
    69318,69179
  • 69318 - Integrin alpha N-terminal domain
  • 69179 - Integrin domains
  • 0.4323Inherited
    69179,69179
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 0.4323Inherited
    49562,49562
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.5366Inherited
    52440,56059
  • 52440 - PreATP-grasp domain
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 0.5406Inherited
    57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.8071Inherited
    90123,52540
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.8081Inherited
    55550,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.8414Inherited
    57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 0.8737Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    49503,49503,49503
  • 49503 - Cupredoxins
  • 49503 - Cupredoxins
  • 49503 - Cupredoxins
  • 0Direct
    56496,49899,49899
  • 56496 - Fibrinogen C-terminal domain-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    63411,63411,63411
  • 63411 - LuxS/MPP-like metallohydrolase
  • 63411 - LuxS/MPP-like metallohydrolase
  • 63411 - LuxS/MPP-like metallohydrolase
  • 0Direct
    57196,90193,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 90193 - Notch domain
  • 0Direct
    63825,57196,57424
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 57424 - LDL receptor-like module
  • 0Direct
    75399,75399,75399
  • 75399 - Plakin repeat
  • 75399 - Plakin repeat
  • 75399 - Plakin repeat
  • 0Direct
    48726,82895,82895
  • 48726 - Immunoglobulin
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 0Direct
    57184,49899,49899
  • 57184 - Growth factor receptor domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    57184,52058,57184
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0Direct
    48726,48726,82895
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 82895 - TSP-1 type 1 repeat
  • 0Direct
    57196,56496,49899
  • 57196 - EGF/Laminin
  • 56496 - Fibrinogen C-terminal domain-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    49899,49899,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 0Direct
    47473,47473,57850
  • 47473 - EF-hand
  • 47473 - EF-hand
  • 57850 - RING/U-box
  • 0Direct
    52058,48726,48726
  • 52058 - L domain-like
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0Direct
    101288,50156,50044
  • 101288 - L27 domain
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 0Direct
    46966,51045,47473
  • 46966 - Spectrin repeat
  • 51045 - WW domain
  • 47473 - EF-hand
  • 0Direct
    50729,50156,50156
  • 50729 - PH domain-like
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 0Direct
    49899,57196,56496
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 56496 - Fibrinogen C-terminal domain-like
  • 0Direct
    51338,51556,51338
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 51556 - Metallo-dependent hydrolases
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 0Direct
    57196,57424,57424
  • 57196 - EGF/Laminin
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0Direct
    46966,46966,51045
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 51045 - WW domain
  • 0Direct
    49785,49899,49899
  • 49785 - Galactose-binding domain-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    51045,47473,47473
  • 51045 - WW domain
  • 47473 - EF-hand
  • 47473 - EF-hand
  • 0Direct
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.000408Direct
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.0004144Direct
    46966,46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.000467Direct
    49899,49899,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.002196Inherited
    49899,57196,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.002267Inherited
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.003405Inherited
    81296,81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 81296 - E set domains
  • 0.003405Inherited
    48726,48726,49265
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.003935Inherited
    57424,57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.004425Inherited
    57424,57424,57184
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57184 - Growth factor receptor domain
  • 0.01141Inherited
    55781,55781,109604
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 109604 - HD-domain/PDEase-like
  • 0.01141Inherited
    57424,57184,63825
  • 57424 - LDL receptor-like module
  • 57184 - Growth factor receptor domain
  • 63825 - YWTD domain
  • 0.01141Inherited
    50044,50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0.01141Inherited
    48065,50729,50044
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 50044 - SH3-domain
  • 0.02512Inherited
    52058,57184,52058
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.03816Inherited
    101912,103575,48726
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 48726 - Immunoglobulin
  • 0.04918Inherited
    57184,57196,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.05077Inherited
    57535,49854,57535
  • 57535 - Complement control module/SCR domain
  • 49854 - Spermadhesin, CUB domain
  • 57535 - Complement control module/SCR domain
  • 0.05384Inherited
    49854,57535,49854
  • 49854 - Spermadhesin, CUB domain
  • 57535 - Complement control module/SCR domain
  • 49854 - Spermadhesin, CUB domain
  • 0.05384Inherited
    57196,57184,57196
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.1337Inherited
    49854,57535,57535
  • 49854 - Spermadhesin, CUB domain
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.2347Inherited
    69179,69179,69179
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 0.3004Inherited
    49313,49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.3324Inherited
    69318,69179,69179
  • 69318 - Integrin alpha N-terminal domain
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 0.4323Inherited
    57535,57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.6059Inherited
    50044,55550,56112
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.6651Inherited
    57667,57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 0.972Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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