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Mammalian Phenotype (MP): nervous system phenotype

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ 1:   mammalian phenotype [MP:0000001] <29>
0:   nervous system phenotype [MP:0003631] <2>(98|127) (112|79|50)
- 1:   abnormal nervous system physiology [MP:0003633] <38>(43|58) (51|31|18)
- 1:   abnormal nervous system morphology [MP:0003632] <17>(76|104) (91|64|47)


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Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Oligoxyloglucan reducing end-specific cellobiohydrolase0Direct
Tubby C-terminal domain-like0Direct
Composite domain of metallo-dependent hydrolases0Direct
E2F-DP heterodimerization region0Direct
Metallothionein0Direct
Notch domain0Direct
Nitric oxide (NO) synthase oxygenase domain0Direct
Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain0Direct
Proton glutamate symport protein0Direct
Hedgehog/DD-peptidase0Direct
Hedgehog/intein (Hint) domain0Direct
Lamin A/C globular tail domain0Direct
Synuclein0Direct
Homeodomain-like0.0000000000005347Direct
Neurotransmitter-gated ion-channel transmembrane pore0.0000000003584Direct
Nicotinic receptor ligand binding domain-like0.0000000003584Direct
Periplasmic binding protein-like I0.00000002854Direct
PDZ domain-like0.000003416Direct
HLH, helix-loop-helix DNA-binding domain0.00002448Direct
Voltage-gated potassium channels0.000039Direct
Spectrin repeat0.000125Direct
Periplasmic binding protein-like II0.000126Direct
Nuclear receptor ligand-binding domain0.0002274Direct
NHL repeat0.0003398Direct
Sema domain0.0003674Direct
Frizzled cysteine-rich domain0.0005288Direct
Plexin repeat0.000559Direct
Galactose-binding domain-like0.001582Inherited
L27 domain0.001744Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.005401Inherited
Family A G protein-coupled receptor-like0.006349Inherited
Fibronectin type III0.007542Inherited
Orange domain-like0.008323Inherited
Caspase-like0.01071Inherited
YWTD domain0.01319Inherited
GAF domain-like0.01751Inherited
EGF/Laminin0.02282Inherited
Concanavalin A-like lectins/glucanases0.02392Inherited
C2 domain (Calcium/lipid-binding domain, CaLB)0.0247Inherited
p53-like transcription factors0.02698Inherited
SMAD MH1 domain0.02866Inherited
SNF-like0.04278Inherited
Cupredoxins0.04278Inherited
SH3-domain0.05314Inherited
Doublecortin (DC)0.05367Inherited
HCP-like0.05367Inherited
Riboflavin synthase domain-like0.06744Inherited
Metallo-dependent hydrolases0.06744Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.06744Inherited
SRF-like0.07328Inherited
GDNF receptor-like0.07328Inherited
HMA, heavy metal-associated domain0.07328Inherited
Growth factor receptor domain0.08637Inherited
lambda repressor-like DNA-binding domains0.08694Inherited
GTPase activation domain, GAP0.1001Inherited
Clc chloride channel0.1065Inherited
Heat shock protein 70kD (HSP70), C-terminal subdomain0.1065Inherited
Bcl-2 inhibitors of programmed cell death0.1096Inherited
TIMP-like0.1294Inherited
cAMP-binding domain-like0.1608Inherited
PH domain-like0.1611Inherited
Cysteine-rich domain0.1667Inherited
Kringle-like0.1679Inherited
Cystine-knot cytokines0.1683Inherited
Flavoproteins0.1747Inherited
Cap-Gly domain0.1747Inherited
Cadherin-like0.1898Inherited
SNARE fusion complex0.1911Inherited
L domain-like0.1957Inherited
4-helical cytokines0.237Inherited
Cyclin-like0.2389Inherited
Zn-dependent exopeptidases0.26Inherited
Immunoglobulin0.2601Inherited
Formate/glycerate dehydrogenase catalytic domain-like0.2765Inherited
CBS-domain pair0.3014Inherited
Second domain of FERM0.3118Inherited
Integrin domains0.4386Inherited
SAM/Pointed domain0.4814Inherited
Spermadhesin, CUB domain0.4874Inherited
PLP-dependent transferases0.5056Inherited
MFS general substrate transporter0.5267Inherited
BAR/IMD domain-like0.531Inherited
HD-domain/PDEase-like0.5444Inherited
HMG-box0.6037Inherited
TNF receptor-like0.6054Inherited
Toll/Interleukin receptor TIR domain0.6216Inherited
Bromodomain0.6471Inherited
PreATP-grasp domain0.6707Inherited
Intermediate filament protein, coiled coil region0.7143Inherited
Complement control module/SCR domain0.7398Inherited
FAD/NAD(P)-binding domain0.7729Inherited
ABC transporter transmembrane region0.8398Inherited
Glutathione synthetase ATP-binding domain-like0.8773Inherited
SAP domain0.8901Inherited
beta-beta-alpha zinc fingers0.9352Inherited
alpha/beta-Hydrolases0.9746Inherited
Cysteine proteinases1Inherited
RNA-binding domain, RBD1Inherited


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Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Synuclein0Direct
Proton glutamate symport protein0Direct
Nitric oxide (NO) synthase oxygenase domain0Direct
Retinoblastoma tumor suppressor domains0Direct
Hedgehog (development protein), N-terminal signaling domain0Direct
Hydantoinase (dihydropyrimidinase)0Direct
Neurotrophin0Direct
Hedgehog C-terminal (Hog) autoprocessing domain0Direct
Cytochrome p450 reductase N-terminal domain-like0Direct
Oligoxyloglucan reducing end-specific cellobiohydrolase0Direct
Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain0Direct
Synapsin C-terminal domain0Direct
Other IPT/TIG domains0Direct
Synapsin domain0Direct
E2F dimerization segment0Direct
Lamin A/C globular tail domain0Direct
Transcriptional factor tubby, C-terminal domain0Direct
Notch domain0Direct
Metallothionein0Direct
Hydantoinase (dihydropyrimidinase), catalytic domain0Direct
Homeodomain0.000000000001318Direct
Nicotinic receptor ligand binding domain-like0.0000000004021Direct
Neurotransmitter-gated ion-channel transmembrane pore0.0000000004021Direct
L-arabinose binding protein-like0.0000006848Direct
Laminin G-like module0.000001356Direct
Phosphate binding protein-like0.000005024Direct
PDZ domain0.00002333Direct
HLH, helix-loop-helix DNA-binding domain0.00003345Direct
Nuclear receptor0.00006438Direct
Nuclear receptor ligand-binding domain0.0002256Direct
Sema domain0.0003234Direct
Frizzled cysteine-rich domain0.0004282Direct
Plexin repeat0.0005179Direct
Spectrin repeat0.0007573Direct
Laminin-type module0.0008456Direct
L27 domain0.001307Inherited
Hypoxia-inducible factor Hif2a, C-terminal domain0.002305Inherited
Caspase catalytic domain0.002932Inherited
DEP domain0.002932Inherited
Rhodopsin-like0.00345Inherited
Voltage-gated potassium channels0.004664Inherited
Ephrin ectodomain0.006411Inherited
Hairy Orange domain0.006411Inherited
Fibronectin type III0.01016Inherited
YWTD domain0.011Inherited
Cell cycle transcription factor e2f-dp0.01198Inherited
Paired domain0.01198Inherited
GAF domain0.0138Inherited
DIX domain0.0138Inherited
I set domains0.01607Inherited
LDL receptor-like module0.02322Inherited
SMAD MH1 domain0.02344Inherited
SMAD domain0.02344Inherited
NADPH-cytochrome p450 reductase FAD-binding domain-like0.02911Inherited
NADPH-cytochrome p450 reductase-like0.02911Inherited
Enabled/VASP homology 1 domain (EVH1 domain)0.02988Inherited
Extracellular domain of cell surface receptors0.02988Inherited
SNF-like0.03702Inherited
cAMP-binding domain0.03746Inherited
L domain0.04466Inherited
Doublecortin (DC)0.04466Inherited
Formate/glycerate dehydrogenases, substrate-binding domain0.06081Inherited
beta-glycanases0.06081Inherited
Multidrug efflux transporter AcrB transmembrane domain0.06081Inherited
GDNF receptor-like0.06081Inherited
SRF-like0.06081Inherited
Mib/herc2 domain0.06081Inherited
HMA, heavy metal-associated domain0.06081Inherited
SH3-domain0.06596Inherited
Pyridoxal-dependent decarboxylase0.08336Inherited
Heat shock protein 70kD (HSP70), C-terminal subdomain0.09347Inherited
Clc chloride channel0.09347Inherited
NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain0.09716Inherited
Ephrin receptor ligand binding domain0.09716Inherited
Rel/Dorsal transcription factors, DNA-binding domain0.09761Inherited
Bcl-2 inhibitors of programmed cell death0.09761Inherited
Forkhead DNA-binding domain0.1047Inherited
Ngr ectodomain-like0.1197Inherited
EGF-type module0.1274Inherited
Phosphotyrosine-binding domain (PTB)0.1299Inherited
POU-specific domain0.1344Inherited
EF-hand modules in multidomain proteins0.1344Inherited
Cap-Gly domain0.1572Inherited
Tetramerization domain of potassium channels0.1808Inherited
SNARE fusion complex0.1808Inherited
Cadherin0.2021Inherited
Long-chain cytokines0.2045Inherited
Motor proteins0.2084Inherited
Protein kinase cysteine-rich domain (cys2, phorbol-binding domain)0.2156Inherited
CBS-domain pair0.2174Inherited
Calmodulin-like0.2186Inherited
Synaptotagmin-like (S variant)0.2298Inherited
Fibronectin type II module0.2305Inherited
Adenylyl and guanylyl cyclase catalytic domain0.2323Inherited
SAM (sterile alpha motif) domain0.2375Inherited
Formate/glycerate dehydrogenases, NAD-domain0.2559Inherited
Leucine zipper domain0.2828Inherited
Transforming growth factor (TGF)-beta0.2943Inherited
Acetylcholinesterase-like0.311Inherited
PLC-like (P variant)0.3138Inherited
FYVE, a phosphatidylinositol-3-phosphate binding domain0.3625Inherited
Cyclin0.3736Inherited
Cytoplasmic domain of inward rectifier potassium channel0.3938Inherited
Growth factor receptor domain0.394Inherited
PDEase0.4042Inherited
p120GAP domain-like0.4304Inherited
Integrin domains0.4363Inherited
Actin/HSP700.438Inherited
Integrin alpha N-terminal domain0.438Inherited
C1 set domains (antibody constant domain-like)0.438Inherited
Spermadhesin, CUB domain0.4967Inherited
TNF receptor-like0.511Inherited
HMG-box0.6135Inherited
Bromodomain0.6502Inherited
G proteins0.6875Inherited
BAR domain0.69Inherited
Toll/Interleukin receptor TIR domain0.7123Inherited
Intermediate filament protein, coiled coil region0.7231Inherited
Complement control module/SCR domain0.7459Inherited
ABC transporter transmembrane region0.8395Inherited
SAP domain0.8856Inherited
MAM domain0.8856Inherited
Classic zinc finger, C2H20.8998Inherited
SH2 domain0.9018Inherited
ABC transporter ATPase domain-like0.915Inherited
Canonical RBD0.9693Inherited
V set domains (antibody variable domain-like)1Inherited


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Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Composite domain of metallo-dependent hydrolases0Direct
Metallothionein0Direct
Oligoxyloglucan reducing end-specific cellobiohydrolase0Direct
E2F-DP heterodimerization region0Direct
Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain0Direct
Proton glutamate symport protein0Direct
Hedgehog/intein (Hint) domain0Direct
Lamin A/C globular tail domain0Direct
Tubby C-terminal domain-like0Direct
Hedgehog/DD-peptidase0Direct
Synuclein0Direct
Notch domain0Direct
Nitric oxide (NO) synthase oxygenase domain0Direct
Homeodomain-like0.0000000000001938Direct
Nicotinic receptor ligand binding domain-like0.0000000001319Direct
Neurotransmitter-gated ion-channel transmembrane pore0.0000000001319Direct
Periplasmic binding protein-like I0.00000001093Direct
PDZ domain-like0.000001449Direct
HLH, helix-loop-helix DNA-binding domain0.00001112Direct
Voltage-gated potassium channels0.00001807Direct
Spectrin repeat0.00006153Direct
Periplasmic binding protein-like II0.00006208Direct
Nuclear receptor ligand-binding domain0.0001155Direct
NHL repeat0.0001768Direct
Sema domain0.0001913Direct
Frizzled cysteine-rich domain0.0002801Direct
Plexin repeat0.000297Direct
Galactose-binding domain-like0.0008879Direct
L27 domain0.0009852Direct
Glucocorticoid receptor-like (DNA-binding domain)0.003249Inherited
Family A G protein-coupled receptor-like0.003864Inherited
Fibronectin type III0.004629Inherited
Orange domain-like0.005144Inherited
Caspase-like0.006736Inherited
YWTD domain0.008406Inherited
GAF domain-like0.01141Inherited
EGF/Laminin0.01515Inherited
Concanavalin A-like lectins/glucanases0.01594Inherited
C2 domain (Calcium/lipid-binding domain, CaLB)0.01652Inherited
LDL receptor-like module0.01655Inherited
p53-like transcription factors0.01817Inherited
SMAD MH1 domain0.01941Inherited
SNF-like0.02989Inherited
Cupredoxins0.02989Inherited
SH3-domain0.03776Inherited
HCP-like0.03816Inherited
Doublecortin (DC)0.03816Inherited
E set domains0.04258Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.04917Inherited
Riboflavin synthase domain-like0.04917Inherited
Metallo-dependent hydrolases0.04917Inherited
HMA, heavy metal-associated domain0.05383Inherited
Mib/herc2 domain-like0.05383Inherited
SRF-like0.05383Inherited
GDNF receptor-like0.05383Inherited
Growth factor receptor domain0.06433Inherited
lambda repressor-like DNA-binding domains0.06478Inherited
Glutamine synthetase/guanido kinase0.07313Inherited
GTPase activation domain, GAP0.0756Inherited
Heat shock protein 70kD (HSP70), C-terminal subdomain0.0811Inherited
Clc chloride channel0.0811Inherited
Multidrug efflux transporter AcrB transmembrane domain0.0811Inherited
Bcl-2 inhibitors of programmed cell death0.08377Inherited
TIMP-like0.1007Inherited
cAMP-binding domain-like0.1282Inherited
PH domain-like0.1285Inherited
Cysteine-rich domain0.1333Inherited
Kringle-like0.1344Inherited
Cystine-knot cytokines0.1346Inherited
Cap-Gly domain0.1405Inherited
Flavoproteins0.1405Inherited
Cadherin-like0.1541Inherited
SNARE fusion complex0.1553Inherited
L domain-like0.1596Inherited
BRCT domain0.1727Inherited
4-helical cytokines0.1977Inherited
Cyclin-like0.1995Inherited
Nucleotide cyclase0.2021Inherited
Zn-dependent exopeptidases0.2191Inherited
Immunoglobulin0.2192Inherited
Leucine zipper domain0.2333Inherited
Formate/glycerate dehydrogenase catalytic domain-like0.2347Inherited
CBS-domain pair0.2582Inherited
Second domain of FERM0.2681Inherited
"Winged helix" DNA-binding domain0.3032Inherited
ARM repeat0.3243Inherited
Quinoprotein alcohol dehydrogenase-like0.3288Inherited
Integrin domains0.3912Inherited
TPR-like0.4029Inherited
Integrin alpha N-terminal domain0.4232Inherited
SAM/Pointed domain0.4338Inherited
Spermadhesin, CUB domain0.4399Inherited
PLP-dependent transferases0.4581Inherited
MFS general substrate transporter0.4795Inherited
BAR/IMD domain-like0.484Inherited
HD-domain/PDEase-like0.4976Inherited
HMG-box0.5583Inherited
TNF receptor-like0.5601Inherited
Toll/Interleukin receptor TIR domain0.5768Inherited
Bromodomain0.6037Inherited
PreATP-grasp domain0.6285Inherited
Intermediate filament protein, coiled coil region0.6744Inherited
Complement control module/SCR domain0.7013Inherited
FAD/NAD(P)-binding domain0.736Inherited
ABC transporter transmembrane region0.8081Inherited
Glutathione synthetase ATP-binding domain-like0.8485Inherited
SH2 domain0.8524Inherited
SAP domain0.8625Inherited
beta-beta-alpha zinc fingers0.9119Inherited
alpha/beta-Hydrolases0.9566Inherited
RNA-binding domain, RBD0.992Inherited
Cysteine proteinases1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
50729,50156
  • 50729 - PH domain-like
  • 50156 - PDZ domain-like
  • 0Direct
    49785,49899
  • 49785 - Galactose-binding domain-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    57184,49899
  • 57184 - Growth factor receptor domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    81296,101898
  • 81296 - E set domains
  • 101898 - NHL repeat
  • 0Direct
    48726,82895
  • 48726 - Immunoglobulin
  • 82895 - TSP-1 type 1 repeat
  • 0Direct
    81324,53850
  • 81324 - Voltage-gated potassium channels
  • 53850 - Periplasmic binding protein-like II
  • 0Direct
    51556,51338
  • 51556 - Metallo-dependent hydrolases
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 0Direct
    57196,57424
  • 57196 - EGF/Laminin
  • 57424 - LDL receptor-like module
  • 0Direct
    57196,56496
  • 57196 - EGF/Laminin
  • 56496 - Fibrinogen C-terminal domain-like
  • 0Direct
    101288,50156
  • 101288 - L27 domain
  • 50156 - PDZ domain-like
  • 0Direct
    46966,51045
  • 46966 - Spectrin repeat
  • 51045 - WW domain
  • 0Direct
    47473,57850
  • 47473 - EF-hand
  • 57850 - RING/U-box
  • 0Direct
    57196,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0Direct
    51045,47473
  • 51045 - WW domain
  • 47473 - EF-hand
  • 0Direct
    56496,49899
  • 56496 - Fibrinogen C-terminal domain-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    51338,51556
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 51556 - Metallo-dependent hydrolases
  • 0Direct
    55166,51294
  • 55166 - Hedgehog/DD-peptidase
  • 51294 - Hedgehog/intein (Hint) domain
  • 0Direct
    64593,74853
  • 64593 - Intermediate filament protein, coiled coil region
  • 74853 - Lamin A/C globular tail domain
  • 0Direct
    49562,51045
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 51045 - WW domain
  • 0Direct
    46785,144074
  • 46785 - "Winged helix" DNA-binding domain
  • 144074 - E2F-DP heterodimerization region
  • 0Direct
    90193,90193
  • 90193 - Notch domain
  • 90193 - Notch domain
  • 0Direct
    50729,57889
  • 50729 - PH domain-like
  • 57889 - Cysteine-rich domain
  • 0Direct
    50044,50156
  • 50044 - SH3-domain
  • 50156 - PDZ domain-like
  • 0Direct
    63712,90112
  • 63712 - Nicotinic receptor ligand binding domain-like
  • 90112 - Neurotransmitter-gated ion-channel transmembrane pore
  • 0.0000000001319Direct
    49899,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 0.00001159Direct
    49899,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.0001592Direct
    50156,50156
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 0.0001913Direct
    101912,103575
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 0.0001913Direct
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.000222Direct
    46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.0002801Direct
    63825,57196
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 0.0009852Direct
    47459,158457
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 158457 - Orange domain-like
  • 0.005144Inherited
    57424,57184
  • 57424 - LDL receptor-like module
  • 57184 - Growth factor receptor domain
  • 0.005144Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.006132Inherited
    57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.009635Inherited
    53822,53850
  • 53822 - Periplasmic binding protein-like I
  • 53850 - Periplasmic binding protein-like II
  • 0.01141Inherited
    55781,55781
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 0.01141Inherited
    55781,109604
  • 55781 - GAF domain-like
  • 109604 - HD-domain/PDEase-like
  • 0.01141Inherited
    47986,52129
  • 47986 - DEATH domain
  • 52129 - Caspase-like
  • 0.01141Inherited
    57196,63825
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 0.01141Inherited
    47473,47473
  • 47473 - EF-hand
  • 47473 - EF-hand
  • 0.01717Inherited
    57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.01941Inherited
    57184,49265
  • 57184 - Growth factor receptor domain
  • 49265 - Fibronectin type III
  • 0.02512Inherited
    63501,50242
  • 63501 - Frizzled cysteine-rich domain
  • 50242 - TIMP-like
  • 0.02512Inherited
    81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 0.0311Inherited
    52058,57184
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.03816Inherited
    57196,49899
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.03816Inherited
    57184,52058
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.03816Inherited
    57184,63825
  • 57184 - Growth factor receptor domain
  • 63825 - YWTD domain
  • 0.03816Inherited
    89837,89837
  • 89837 - Doublecortin (DC)
  • 89837 - Doublecortin (DC)
  • 0.03816Inherited
    57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.04896Inherited
    103575,48726
  • 103575 - Plexin repeat
  • 48726 - Immunoglobulin
  • 0.04917Inherited
    48452,81901
  • 48452 - TPR-like
  • 81901 - HCP-like
  • 0.05383Inherited
    57535,49854
  • 57535 - Complement control module/SCR domain
  • 49854 - Spermadhesin, CUB domain
  • 0.05383Inherited
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.05776Inherited
    50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0.07201Inherited
    47413,46689
  • 47413 - lambda repressor-like DNA-binding domains
  • 46689 - Homeodomain-like
  • 0.07201Inherited
    81324,81324
  • 81324 - Voltage-gated potassium channels
  • 81324 - Voltage-gated potassium channels
  • 0.0811Inherited
    56112,47769
  • 56112 - Protein kinase-like (PK-like)
  • 47769 - SAM/Pointed domain
  • 0.08161Inherited
    49417,81296
  • 49417 - p53-like transcription factors
  • 81296 - E set domains
  • 0.08377Inherited
    49562,48350
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48350 - GTPase activation domain, GAP
  • 0.1405Inherited
    56112,55073
  • 56112 - Protein kinase-like (PK-like)
  • 55073 - Nucleotide cyclase
  • 0.1405Inherited
    52058,48726
  • 52058 - L domain-like
  • 48726 - Immunoglobulin
  • 0.1928Inherited
    49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.2127Inherited
    57184,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.2157Inherited
    52283,51735
  • 52283 - Formate/glycerate dehydrogenase catalytic domain-like
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0.2347Inherited
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.3352Inherited
    49854,57535
  • 49854 - Spermadhesin, CUB domain
  • 57535 - Complement control module/SCR domain
  • 0.3399Inherited
    81324,81296
  • 81324 - Voltage-gated potassium channels
  • 81296 - E set domains
  • 0.3609Inherited
    57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.3609Inherited
    57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.3706Inherited
    69318,69179
  • 69318 - Integrin alpha N-terminal domain
  • 69179 - Integrin domains
  • 0.4324Inherited
    69179,69179
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 0.4324Inherited
    49562,49562
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.5366Inherited
    52440,56059
  • 52440 - PreATP-grasp domain
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 0.5406Inherited
    57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.807Inherited
    90123,52540
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.8081Inherited
    55550,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.8413Inherited
    57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 0.8736Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    51338,51556,51338
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 51556 - Metallo-dependent hydrolases
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 0Direct
    57196,90193,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 90193 - Notch domain
  • 0Direct
    57196,57424,57424
  • 57196 - EGF/Laminin
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0Direct
    51045,47473,47473
  • 51045 - WW domain
  • 47473 - EF-hand
  • 47473 - EF-hand
  • 0Direct
    50729,50156,50156
  • 50729 - PH domain-like
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 0Direct
    57184,49899,49899
  • 57184 - Growth factor receptor domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    49899,49899,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 0Direct
    46966,46966,51045
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 51045 - WW domain
  • 0Direct
    63825,57196,57424
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 57424 - LDL receptor-like module
  • 0Direct
    63411,63411,63411
  • 63411 - LuxS/MPP-like metallohydrolase
  • 63411 - LuxS/MPP-like metallohydrolase
  • 63411 - LuxS/MPP-like metallohydrolase
  • 0Direct
    49899,57196,56496
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 56496 - Fibrinogen C-terminal domain-like
  • 0Direct
    57196,56496,49899
  • 57196 - EGF/Laminin
  • 56496 - Fibrinogen C-terminal domain-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    46966,51045,47473
  • 46966 - Spectrin repeat
  • 51045 - WW domain
  • 47473 - EF-hand
  • 0Direct
    48726,82895,82895
  • 48726 - Immunoglobulin
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 0Direct
    47473,47473,57850
  • 47473 - EF-hand
  • 47473 - EF-hand
  • 57850 - RING/U-box
  • 0Direct
    49785,49899,49899
  • 49785 - Galactose-binding domain-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    101288,50156,50044
  • 101288 - L27 domain
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 0Direct
    75399,75399,75399
  • 75399 - Plakin repeat
  • 75399 - Plakin repeat
  • 75399 - Plakin repeat
  • 0Direct
    57184,52058,57184
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0Direct
    48726,48726,82895
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 82895 - TSP-1 type 1 repeat
  • 0Direct
    56496,49899,49899
  • 56496 - Fibrinogen C-terminal domain-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    52058,48726,48726
  • 52058 - L domain-like
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0Direct
    49503,49503,49503
  • 49503 - Cupredoxins
  • 49503 - Cupredoxins
  • 49503 - Cupredoxins
  • 0Direct
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.0004081Direct
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.0004146Direct
    46966,46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.0004671Direct
    49899,49899,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.002197Inherited
    49899,57196,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.002268Inherited
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.003407Inherited
    81296,81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 81296 - E set domains
  • 0.003407Inherited
    48726,48726,49265
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.003936Inherited
    57424,57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.004427Inherited
    57424,57184,63825
  • 57424 - LDL receptor-like module
  • 57184 - Growth factor receptor domain
  • 63825 - YWTD domain
  • 0.01141Inherited
    57424,57424,57184
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57184 - Growth factor receptor domain
  • 0.01141Inherited
    55781,55781,109604
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 109604 - HD-domain/PDEase-like
  • 0.01141Inherited
    50044,50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0.01141Inherited
    48065,50729,50044
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 50044 - SH3-domain
  • 0.02512Inherited
    52058,57184,52058
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.03816Inherited
    101912,103575,48726
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 48726 - Immunoglobulin
  • 0.04917Inherited
    57184,57196,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.05077Inherited
    57535,49854,57535
  • 57535 - Complement control module/SCR domain
  • 49854 - Spermadhesin, CUB domain
  • 57535 - Complement control module/SCR domain
  • 0.05383Inherited
    49854,57535,49854
  • 49854 - Spermadhesin, CUB domain
  • 57535 - Complement control module/SCR domain
  • 49854 - Spermadhesin, CUB domain
  • 0.05383Inherited
    57196,57184,57196
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.1337Inherited
    49854,57535,57535
  • 49854 - Spermadhesin, CUB domain
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.2347Inherited
    69179,69179,69179
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 0.3004Inherited
    49313,49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.3324Inherited
    69318,69179,69179
  • 69318 - Integrin alpha N-terminal domain
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 0.4324Inherited
    57535,57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.6059Inherited
    50044,55550,56112
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.6651Inherited
    57667,57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 0.972Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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