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Mammalian Phenotype (MP): abnormal pituitary hormone level

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   mammalian phenotype [MP:0000001] <29>
+ + + 3:   homeostasis/metabolism phenotype [MP:0005376] <7>(140|174) (149|96|44)
+ + 2:   abnormal homeostasis [MP:0001764] <27>(103|129) (113|73|31)
+ 1:   abnormal hormone level [MP:0003953] <15>(27|29) (30|17|8)
0:   abnormal pituitary hormone level [MP:0003965] <9>(7|7) (8|2|0)
- 1:   decreased pituitary hormone level [MP:0003972] <7>(1|2) (2|2|0)
- 1:   increased pituitary hormone level [MP:0003973] <7>(3|2) (3|0|0)
- 1:   abnormal adrenocorticotropin level [MP:0003966] <2>(0|0) (0|0|0)
- 1:   abnormal circulating pituitary hormone level [MP:0005116] <2>(6|5) (6|1|0)
- 1:   abnormal follicle stimulating hormone level [MP:0003967] <2>(2|4) (3|0|0)
- 1:   abnormal growth hormone level [MP:0003968] <2>(0|0) (0|0|0)
- 1:   abnormal luteinizing hormone level [MP:0003969] <2>(0|3) (1|0|0)
- 1:   abnormal prolactin level [MP:0003970] <2>(0|0) (0|0|0)
- 1:   abnormal thyroid-stimulating hormone level [MP:0003971] <2>(0|0) (0|1|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Glucocorticoid receptor-like (DNA-binding domain)0.00005149Direct
Nuclear receptor ligand-binding domain0.00247Inherited
Cystine-knot cytokines0.002517Inherited
SMAD MH1 domain0.006558Inherited
Heme-dependent peroxidases0.01962Inherited
Riboflavin synthase domain-like0.09799Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.09799Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Transforming growth factor (TGF)-beta0.0005949Direct
Nuclear receptor0.001368Inherited
Nuclear receptor ligand-binding domain0.002284Inherited
SMAD MH1 domain0.005051Inherited
SMAD domain0.005051Inherited
Myeloperoxidase-like0.01555Inherited
Forkhead DNA-binding domain0.05029Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Glucocorticoid receptor-like (DNA-binding domain)0.00002423Direct
Nuclear receptor ligand-binding domain0.001419Inherited
Cystine-knot cytokines0.001447Inherited
SMAD MH1 domain0.003995Inherited
Heme-dependent peroxidases0.01285Inherited
SMAD/FHA domain0.01316Inherited
Riboflavin synthase domain-like0.07382Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.07382Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.002487Inherited
    57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.03619Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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