SUPERFAMILY 1.75 HMM library and genome assignments server

Superfamily is undergoing a server migration - you are now browsing on the new server. Please contact us if you experience any problems.

Mammalian Phenotype (MP): abnormal B cell morphology

(show info)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + + + 7:   mammalian phenotype [MP:0000001] <29>
+ + + + + + 6:   immune system phenotype [MP:0005387] <2>(76|114) (86|66|35)
+ + + + + + 6:   hematopoietic system phenotype [MP:0005397] <2>(72|102) (78|63|30)
+ + + + + 5:   abnormal immune system morphology [MP:0000685] <3>(51|76) (60|35|18)
+ + + + + 5:   abnormal hematopoietic system morphology/development [MP:0002396] <5>(58|86) (66|47|21)
+ + + + 4:   abnormal immune system cell morphology [MP:0000716] <5>(38|63) (48|29|16)
+ + + + 4:   abnormal hematopoietic cell morphology [MP:0013656] <9>(49|77) (60|43|18)
+ + + 3:   abnormal leukocyte morphology [MP:0008246] <4>(37|62) (47|29|15)
+ + 2:   abnormal mononuclear cell morphology [MP:0008247] <2>(34|57) (41|28|14)
+ 1:   abnormal lymphocyte morphology [MP:0002619] <5>(28|46) (33|26|14)
0:   abnormal B cell morphology [MP:0004939] <6>(18|28) (20|11|6)
- 1:   abnormal B cell differentiation [MP:0002144] <10>(12|17) (13|8|2)
- 1:   abnormal mature B cell morphology [MP:0008171] <9>(9|21) (10|8|4)
- 1:   abnormal B cell number [MP:0002458] <6>(7|18) (8|8|4)
- 1:   abnormal plasma cell morphology [MP:0002439] <4>(1|0) (1|0|0)
- 1:   abnormal immature B cell morphology [MP:0005022] <2>(4|8) (4|6|1)
- 1:   abnormal pre-B cell morphology [MP:0002403] <2>(2|2) (2|1|1)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
SPOC domain-like0Direct
PsbU/PolX domain-like0Direct
DNA polymerase beta, N-terminal domain-like0.0001012Direct
Ran binding protein zinc finger-like0.0002924Direct
BRCT domain0.006864Inherited
WWE domain0.01086Inherited
SMAD/FHA domain0.01136Inherited
DNA/RNA polymerases0.01358Inherited
Nucleotidyltransferase0.02402Inherited
SET domain0.03523Inherited
Bcl-2 inhibitors of programmed cell death0.1186Inherited
Calponin-homology domain, CH-domain0.1515Inherited
SH2 domain0.1739Inherited
DBL homology domain (DH-domain)0.174Inherited
TNF receptor-like0.2658Inherited
DEATH domain0.3158Inherited
Toll/Interleukin receptor TIR domain0.4497Inherited
Immunoglobulin0.9913Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
DNA polymerase beta-like0Direct
BAFF receptor-like0Direct
DNA polymerase beta-like, second domain0Direct
Rel/Dorsal transcription factors, DNA-binding domain0.00000004344Direct
NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain0.0000002568Direct
DNA polymerase beta, N-terminal domain-like0.00005942Direct
Ran binding protein zinc finger-like0.0001873Direct
WWE domain0.004167Inherited
DNA polymerase I0.004167Inherited
ets domain0.007176Inherited
Interferon regulatory factor 3 (IRF3), transactivation domain0.007732Inherited
FHA domain0.02347Inherited
Myb/SANT domain0.05601Inherited
Pleckstrin-homology domain (PH domain)0.0663Inherited
Pointed domain0.09202Inherited
Bcl-2 inhibitors of programmed cell death0.09202Inherited
Interferon regulatory factor0.09202Inherited
Higher-molecular-weight phosphotyrosine protein phosphatases0.1015Inherited
Calponin-homology domain, CH-domain0.1326Inherited
SH2 domain0.1337Inherited
DBL homology domain (DH-domain)0.1389Inherited
Caspase recruitment domain, CARD0.1491Inherited
MATH domain0.1491Inherited
CCCH zinc finger0.1491Inherited
PLC-like (P variant)0.1712Inherited
Toll/Interleukin receptor TIR domain0.2714Inherited
V set domains (antibody variable domain-like)0.5738Inherited
DEATH domain, DD0.6392Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
Plot tree as:   Download Newick format tree:
(show help)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
SPOC domain-like0Direct
PsbU/PolX domain-like0Direct
DNA polymerase beta, N-terminal domain-like0.00004897Direct
Ran binding protein zinc finger-like0.0001503Direct
BRCT domain0.004197Inherited
WWE domain0.006827Inherited
SMAD/FHA domain0.007172Inherited
DNA/RNA polymerases0.008665Inherited
Nucleotidyltransferase0.01599Inherited
SET domain0.02425Inherited
Bcl-2 inhibitors of programmed cell death0.09141Inherited
Calponin-homology domain, CH-domain0.1201Inherited
SH2 domain0.1397Inherited
DBL homology domain (DH-domain)0.1397Inherited
CCCH zinc finger0.1485Inherited
SH3-domain0.1833Inherited
TNF receptor-like0.2245Inherited
DEATH domain0.2717Inherited
Toll/Interleukin receptor TIR domain0.4021Inherited
Immunoglobulin0.9763Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
47802,81585
  • 47802 - DNA polymerase beta, N-terminal domain-like
  • 81585 - PsbU/PolX domain-like
  • 0Direct
    81585,81301
  • 81585 - PsbU/PolX domain-like
  • 81301 - Nucleotidyltransferase
  • 0Direct
    47576,48065
  • 47576 - Calponin-homology domain, CH-domain
  • 48065 - DBL homology domain (DH-domain)
  • 0Direct
    49417,81296
  • 49417 - p53-like transcription factors
  • 81296 - E set domains
  • 0.00000002915Direct
    57850,49599
  • 57850 - RING/U-box
  • 49599 - TRAF domain-like
  • 0.01114Inherited
    55550,55550
  • 55550 - SH2 domain
  • 55550 - SH2 domain
  • 0.05569Inherited
    55550,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.0642Inherited
    50729,55550
  • 50729 - PH domain-like
  • 55550 - SH2 domain
  • 0.09141Inherited
    48065,50729
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0.1397Inherited
    55550,50044
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0.2221Inherited
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.2245Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    50729,50044,55550
  • 50729 - PH domain-like
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0Direct
    47802,81585,81301
  • 47802 - DNA polymerase beta, N-terminal domain-like
  • 81585 - PsbU/PolX domain-like
  • 81301 - Nucleotidyltransferase
  • 0Direct
    47576,48065,50729
  • 47576 - Calponin-homology domain, CH-domain
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0Direct
    50044,55550,56112
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.1397Inherited
    55550,56112,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 56112 - Protein kinase-like (PK-like)
  • 0.1485Inherited
    50729,55550,56112
  • 50729 - PH domain-like
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.1485Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)