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Mammalian Phenotype (MP): abnormal appendicular skeleton morphology

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   mammalian phenotype [MP:0000001] <29>
+ + 2:   skeleton phenotype [MP:0005390] <2>(46|63) (50|41|26)
+ 1:   abnormal skeleton morphology [MP:0005508] <15>(41|59) (47|38|25)
0:   abnormal appendicular skeleton morphology [MP:0009250] <4>(12|17) (17|12|13)
- 1:   abnormal long bone morphology [MP:0003723] <11>(7|13) (11|11|11)
- 1:   abnormal limb bone morphology [MP:0002115] <5>(5|9) (7|8|8)
- 1:   abnormal pectoral girdle bone morphology [MP:0004508] <3>(6|7) (8|0|0)
- 1:   abnormal pelvic girdle bone morphology [MP:0004509] <3>(0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
TB module/8-cys domain0.0001581Direct
Homeodomain-like0.002992Inherited
TIMP-like0.03495Inherited
HMG-box0.04156Inherited
Metalloproteases ("zincins"), catalytic domain0.04263Inherited
PGBD-like0.05273Inherited
(Trans)glycosidases0.06786Inherited
p53-like transcription factors0.07982Inherited
Transducin (alpha subunit), insertion domain0.1725Inherited
YWTD domain0.2738Inherited
Cyclin-like0.289Inherited
HLH, helix-loop-helix DNA-binding domain0.862Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Retinoblastoma tumor suppressor domains0Direct
RUNT domain0Direct
TB module/8-cys domain0.0001046Direct
Homeodomain0.001298Inherited
Hemopexin-like domain0.02172Inherited
HMG-box0.03376Inherited
MMP N-terminal domain0.04196Inherited
Matrix metalloproteases, catalytic domain0.04196Inherited
Arylsulfatase0.07918Inherited
Classic zinc finger, C2H20.08236Inherited
Transforming growth factor (TGF)-beta0.0845Inherited
Fibroblast growth factors (FGF)0.09179Inherited
Transducin (alpha subunit), insertion domain0.1502Inherited
YWTD domain0.2471Inherited
VWC domain0.3257Inherited
Rel/Dorsal transcription factors, DNA-binding domain0.3567Inherited
HLH, helix-loop-helix DNA-binding domain0.8576Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
TB module/8-cys domain0.00007902Direct
Homeodomain-like0.001735Inherited
Spermadhesin, CUB domain0.00422Inherited
Hemopexin-like domain0.01891Inherited
TIMP-like0.02404Inherited
HMG-box0.02894Inherited
Metalloproteases ("zincins"), catalytic domain0.02973Inherited
PGBD-like0.03738Inherited
Kazal-type serine protease inhibitors0.04455Inherited
(Trans)glycosidases0.04947Inherited
p53-like transcription factors0.05891Inherited
beta-beta-alpha zinc fingers0.1031Inherited
Transducin (alpha subunit), insertion domain0.1385Inherited
LDL receptor-like module0.2035Inherited
YWTD domain0.2321Inherited
Cyclin-like0.2464Inherited
HLH, helix-loop-helix DNA-binding domain0.8319Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57184,57581
  • 57184 - Growth factor receptor domain
  • 57581 - TB module/8-cys domain
  • 0Direct
    57196,57581
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 0.000203Direct
    57581,57196
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 0.000203Direct
    48726,56436
  • 48726 - Immunoglobulin
  • 56436 - C-type lectin-like
  • 0.003444Inherited
    47090,55486
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0.03738Inherited
    63501,50242
  • 63501 - Frizzled cysteine-rich domain
  • 50242 - TIMP-like
  • 0.05307Inherited
    57196,63825
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 0.05307Inherited
    57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.07184Inherited
    55486,50923
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 0.1342Inherited
    63825,57196
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 0.1342Inherited
    49417,81296
  • 49417 - p53-like transcription factors
  • 81296 - E set domains
  • 0.3368Inherited
    57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.4817Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57184,57184,57581
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 57581 - TB module/8-cys domain
  • 0Direct
    57184,57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.00002446Direct
    57581,57196,57196
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.00004483Direct
    57196,57196,57581
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 0.00004483Direct
    57196,57581,57184
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 57184 - Growth factor receptor domain
  • 0.0004131Direct
    57581,57196,57581
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 0.001478Inherited
    48726,56436,56436
  • 48726 - Immunoglobulin
  • 56436 - C-type lectin-like
  • 56436 - C-type lectin-like
  • 0.003444Inherited
    57196,63825,57196
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 0.05307Inherited
    57424,57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.07184Inherited
    47090,55486,50923
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 0.1342Inherited
    63825,57196,63825
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 0.1342Inherited
    57196,57184,57196
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.4403Inherited
    57667,57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 0.609Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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