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Mammalian Phenotype (MP): abnormal platelet aggregation

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + + + + 8:   mammalian phenotype [MP:0000001] <29>
+ + + + + + + 7:   homeostasis/metabolism phenotype [MP:0005376] <7>(140|174) (149|96|44)
+ + + + + + 6:   abnormal homeostasis [MP:0001764] <27>(103|129) (113|73|31)
+ + + + + 5:   abnormal blood homeostasis [MP:0009642] <23>(63|82) (70|45|21)
+ + + + + 5:   hematopoietic system phenotype [MP:0005397] <2>(72|102) (78|63|30)
+ + + + 4:   abnormal hematopoietic system physiology [MP:0001545] <5>(39|53) (40|38|21)
+ + + + 4:   abnormal hemostasis [MP:0009676] <1>(13|16) (15|12|5)
+ + + 3:   abnormal blood cell physiology [MP:0012382] <3>(38|53) (39|38|21)
+ + + 3:   abnormal blood coagulation [MP:0002551] <8>(13|16) (15|12|5)
+ + 2:   abnormal platelet physiology [MP:0005464] <2>(5|8) (6|5|1)
+ 1:   abnormal platelet activation [MP:0006298] <1>(5|8) (6|5|1)
0:   abnormal platelet aggregation [MP:0009548] <2>(4|8) (5|5|1)
- 1:   decreased platelet aggregation [MP:0009549](3|4) (4|3|0)
- 1:   increased platelet aggregation [MP:0009586](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
C2 domain (Calcium/lipid-binding domain, CaLB)0.0000007353Direct
Transducin (alpha subunit), insertion domain0.00001454Direct
PLC-like phosphodiesterases0.0002844Direct
Integrin domains0.00201Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
PLC-like (P variant)0.000000006315Direct
Phoshoinositide 3-kinase (PI3K) helical domain0.0000001235Direct
Phoshoinositide 3-kinase (PI3K), catalytic domain0.00000544Direct
Transducin (alpha subunit), insertion domain0.00001157Direct
Mammalian PLC0.0001228Direct
G proteins0.0003097Direct
Pleckstrin-homology domain (PH domain)0.0007535Direct
Integrin domains0.001678Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
C2 domain (Calcium/lipid-binding domain, CaLB)0.0000002974Direct
Transducin (alpha subunit), insertion domain0.00000644Direct
PLC-like phosphodiesterases0.000146Direct
Integrin domains0.001142Inherited
SH2 domain0.003882Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
49562,48371
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 0.00000006249Direct
    48371,56112
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.0000003425Direct
    47895,52540
  • 47895 - Transducin (alpha subunit), insertion domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.00000442Direct
    50729,47473
  • 50729 - PH domain-like
  • 47473 - EF-hand
  • 0.00005617Direct
    51695,49562
  • 51695 - PLC-like phosphodiesterases
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.00005617Direct

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    49562,48371,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.00000006249Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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