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Mammalian Phenotype (MP): abnormal skin adnexa morphology

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + 2:   mammalian phenotype [MP:0000001] <29>
+ 1:   integument phenotype [MP:0010771] <5>(46|64) (53|34|18)
0:   abnormal skin adnexa morphology [MP:0010678] <12>(21|28) (23|21|10)
- 1:   abnormal hair follicle morphology [MP:0000377] <19>(2|2) (2|4|0)
- 1:   abnormal mammary gland morphology [MP:0000627] <17>(11|15) (12|11|5)
- 1:   abnormal sebaceous gland morphology [MP:0000647] <11>(1|1) (2|2|3)
- 1:   abnormal vibrissa morphology [MP:0002098] <11>(0|0) (0|0|0)
- 1:   abnormal nail morphology [MP:0000579] <10>(1|1) (1|1|0)
- 1:   swellings [MP:0013118] <9>(0|0) (0|0|0)
- 1:   abnormal coat/ hair morphology [MP:0000367] <7>(8|9) (10|5|4)
- 1:   abnormal hypodermis morphology [MP:0003705] <5>(1|1) (1|1|0)
- 1:   abnormal sweat gland morphology [MP:0000674] <2>(0|0) (0|0|0)
- 1:   abnormal arrector pilli muscle morphology [MP:0010679](0|0) (0|0|0)
- 1:   abnormal hair follicle orientation [MP:0000383](0|0) (0|0|0)
- 1:   abnormal vibrissa follicle morphology [MP:0010234](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
p53 tetramerization domain0Direct
Di-copper centre-containing domain0Direct
Transcription factor STAT-4 N-domain0.0003409Direct
STAT0.0003409Direct
p53-like transcription factors0.001599Inherited
PAZ domain0.04377Inherited
HLH, helix-loop-helix DNA-binding domain0.06659Inherited
Frizzled cysteine-rich domain0.1072Inherited
Nuclear receptor ligand-binding domain0.1433Inherited
Intermediate filament protein, coiled coil region0.203Inherited
Notch domain0.229Inherited
Band 7/SPFH domain0.229Inherited
Nuclear receptor coactivator interlocking domain0.229Inherited
Homeodomain-like0.2363Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.3287Inherited
Integrin beta tail domain0.3327Inherited
4-helical cytokines0.3814Inherited
Integrin domains0.4022Inherited
EGF/Laminin0.5095Inherited
Cytokine0.8581Inherited
Fibronectin type III0.9224Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
PAS domain of steroid receptor coactivator 1A, NCo-A10Direct
Retinoblastoma tumor suppressor domains0Direct
RUNT domain0Direct
p53 DNA-binding domain-like0Direct
p53 tetramerization domain0Direct
STAT0.0002386Direct
L domain0.0002386Direct
Transcription factor STAT-4 N-domain0.0002386Direct
STAT DNA-binding domain0.0002386Direct
PAZ domain0.03586Inherited
Paired domain0.05177Inherited
HLH, helix-loop-helix DNA-binding domain0.05666Inherited
Frizzled cysteine-rich domain0.08862Inherited
Short-chain cytokines0.08862Inherited
Nuclear receptor ligand-binding domain0.1253Inherited
Nuclear receptor0.1253Inherited
Intermediate filament protein, coiled coil region0.1834Inherited
Nuclear receptor coactivator interlocking domain0.2009Inherited
Notch domain0.2009Inherited
Long-chain cytokines0.303Inherited
Integrin beta EGF-like domains0.303Inherited
Integrin beta tail domain0.303Inherited
Homeodomain0.3451Inherited
EGF-type module0.3605Inherited
Integrin domains0.3736Inherited
FHA domain0.4095Inherited
Fibroblast growth factors (FGF)0.4279Inherited
Fibronectin type III0.9165Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
p53 tetramerization domain0Direct
Di-copper centre-containing domain0Direct
Transcription factor STAT-4 N-domain0.0001772Direct
STAT0.0001772Direct
p53-like transcription factors0.0008984Direct
PAZ domain0.03058Inherited
HLH, helix-loop-helix DNA-binding domain0.04844Inherited
Frizzled cysteine-rich domain0.08161Inherited
Nuclear receptor ligand-binding domain0.1128Inherited
SH2 domain0.1186Inherited
Intermediate filament protein, coiled coil region0.166Inherited
Band 7/SPFH domain0.1902Inherited
Nuclear receptor coactivator interlocking domain0.1902Inherited
Galactose oxidase, central domain0.1902Inherited
Notch domain0.1902Inherited
Homeodomain-like0.197Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.2843Inherited
Integrin beta tail domain0.288Inherited
4-helical cytokines0.3352Inherited
Integrin domains0.3554Inherited
EGF/Laminin0.4619Inherited
Cytokine0.8276Inherited
Fibronectin type III0.8975Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
49417,47719
  • 49417 - p53-like transcription factors
  • 47719 - p53 tetramerization domain
  • 0Direct
    52058,57184
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.0001772Direct
    48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 0.0001772Direct
    57184,52058
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.0001772Direct
    47655,49417
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.0001772Direct
    49417,55550
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.0001772Direct
    57903,51197
  • 57903 - FYVE/PHD zinc finger
  • 51197 - Clavaminate synthase-like
  • 0.0002354Direct
    46579,64593
  • 46579 - Prefoldin
  • 64593 - Intermediate filament protein, coiled coil region
  • 0.001446Inherited
    57196,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0.001446Inherited
    50729,56112
  • 50729 - PH domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0.005078Inherited
    55785,55785
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.008934Inherited
    47459,55785
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.03429Inherited
    57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.05314Inherited
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.05927Inherited
    57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.1487Inherited
    64593,64593
  • 64593 - Intermediate filament protein, coiled coil region
  • 64593 - Intermediate filament protein, coiled coil region
  • 0.2058Inherited
    57196,69687
  • 57196 - EGF/Laminin
  • 69687 - Integrin beta tail domain
  • 0.288Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.3907Inherited
    55550,55550
  • 55550 - SH2 domain
  • 55550 - SH2 domain
  • 0.3929Inherited
    53300,69179
  • 53300 - vWA-like
  • 69179 - Integrin domains
  • 0.3929Inherited
    49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.6618Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57184,52058,57184
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0Direct
    47655,49417,55550
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.0001772Direct
    52058,57184,52058
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.0001772Direct
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.0001772Direct
    47459,55785,55785
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.005078Inherited
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.08161Inherited
    57424,57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.1487Inherited
    57196,57196,69687
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 69687 - Integrin beta tail domain
  • 0.288Inherited
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.4486Inherited
    57184,57196,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.5032Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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