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Mammalian Phenotype (MP): abnormal myeloid cell morphology

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   mammalian phenotype [MP:0000001] <29>
+ + + 3:   hematopoietic system phenotype [MP:0005397] <2>(72|102) (78|63|30)
+ + 2:   abnormal hematopoietic system morphology/development [MP:0002396] <5>(59|86) (66|47|21)
+ 1:   abnormal hematopoietic cell morphology [MP:0013656] <9>(50|76) (60|43|18)
0:   abnormal myeloid cell morphology [MP:0013658] <8>(20|41) (26|23|8)
- 1:   abnormal myeloid cell number [MP:0013661] <6>(4|7) (4|2|0)
- 1:   abnormal platelet morphology [MP:0004720] <6>(1|3) (2|1|0)
- 1:   abnormal erythroid lineage cell morphology [MP:0013659] <5>(8|14) (9|12|6)
- 1:   abnormal myeloid leukocyte morphology [MP:0008250] <2>(11|24) (16|10|2)
- 1:   abnormal embryonic erythrocyte morphology [MP:0004230] <1>(0|0) (0|0|0)
- 1:   abnormal granulocyte monocyte progenitor cell morphology [MP:0013694] <1>(0|0) (0|0|0)
- 1:   abnormal megakaryocyte progenitor cell morphology [MP:0002413] <1>(2|3) (2|3|0)
- 1:   abnormal megakaryocyte-erythroid progenitor cell morphology [MP:0013702] <1>(0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
Integrin beta tail domain0.0002285Direct
Flavoproteins0.003574Inherited
A DNA-binding domain in eukaryotic transcription factors0.009341Inherited
Triple coiled coil domain of C-type lectins0.01165Inherited
AraD/HMP-PK domain-like0.01165Inherited
p53-like transcription factors0.04821Inherited
TIMP-like0.09735Inherited
Nuclear receptor ligand-binding domain0.118Inherited
Cyclin-like0.2396Inherited
Nucleic acid-binding proteins0.2411Inherited
Riboflavin synthase domain-like0.2844Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.2844Inherited
Transcription factor STAT-4 N-domain0.4352Inherited
STAT0.4352Inherited
Terpenoid cyclases/Protein prenyltransferases0.524Inherited
BAR/IMD domain-like0.562Inherited
PH domain-like0.6193Inherited
DEATH domain0.6814Inherited
TNF receptor-like0.9723Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
RUNT domain0Direct
Nitric oxide (NO) synthase oxygenase domain0Direct
Integrin beta tail domain0.0001443Direct
Integrin beta EGF-like domains0.0007154Direct
Erythroid transcription factor GATA-10.006499Inherited
A DNA-binding domain in eukaryotic transcription factors0.007074Inherited
Noncollagenous (NC1) domain of collagen IV0.008201Inherited
Cytochrome p450 reductase N-terminal domain-like0.008414Inherited
Triple coiled coil domain of C-type lectins0.008414Inherited
AraD-like aldolase/epimerase0.008414Inherited
Tissue inhibitor of metalloproteinases, TIMP0.008414Inherited
Long-chain cytokines0.01057Inherited
Tetraspanin0.0251Inherited
NADPH-cytochrome p450 reductase FAD-binding domain-like0.0251Inherited
NADPH-cytochrome p450 reductase-like0.0251Inherited
Hypoxia-inducible factor Hif2a, C-terminal domain0.03583Inherited
Eps15 homology domain (EH domain)0.05055Inherited
NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain0.07856Inherited
Nuclear receptor0.09903Inherited
Nuclear receptor ligand-binding domain0.09903Inherited
Rel/Dorsal transcription factors, DNA-binding domain0.1051Inherited
Cyclin0.1051Inherited
Short-chain cytokines0.1328Inherited
Interferons/interleukin-10 (IL-10)0.1396Inherited
DNA replication initiator (cdc21/cdc54) N-terminal domain0.1856Inherited
PLC-like (P variant)0.2085Inherited
Myb/SANT domain0.2105Inherited
Enabled/VASP homology 1 domain (EVH1 domain)0.246Inherited
Phoshoinositide 3-kinase (PI3K) helical domain0.246Inherited
Phoshoinositide 3-kinase (PI3K), catalytic domain0.262Inherited
Interleukin-1 (IL-1)0.3272Inherited
beta-glycanases0.3272Inherited
STAT0.4011Inherited
Transcription factor STAT-4 N-domain0.4011Inherited
STAT DNA-binding domain0.4011Inherited
Integrin domains0.4811Inherited
C2 set domains0.4901Inherited
Pyrin domain, PYD0.4901Inherited
Pointed domain0.5913Inherited
Interleukin 17F, IL-17F0.5913Inherited
TNF receptor-like0.7846Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
Integrin beta tail domain0.0001161Direct
Flavoproteins0.002095Inherited
A DNA-binding domain in eukaryotic transcription factors0.005817Inherited
Triple coiled coil domain of C-type lectins0.007379Inherited
AraD/HMP-PK domain-like0.007379Inherited
p53-like transcription factors0.03399Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.037Inherited
TIMP-like0.07335Inherited
Nuclear receptor ligand-binding domain0.09097Inherited
C2 domain (Calcium/lipid-binding domain, CaLB)0.1613Inherited
Cyclin-like0.2001Inherited
(Trans)glycosidases0.2015Inherited
Nucleic acid-binding proteins0.2015Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.2422Inherited
Riboflavin synthase domain-like0.2422Inherited
Transcription factor STAT-4 N-domain0.388Inherited
STAT0.388Inherited
Integrin domains0.4636Inherited
C-type lectin-like0.4739Inherited
Terpenoid cyclases/Protein prenyltransferases0.4766Inherited
BAR/IMD domain-like0.5155Inherited
PH domain-like0.5744Inherited
DEATH domain0.6398Inherited
TNF-like0.9163Inherited
TNF receptor-like0.9538Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
53300,69179
  • 53300 - vWA-like
  • 69179 - Integrin domains
  • 0.0001161Direct
    57196,69687
  • 57196 - EGF/Laminin
  • 69687 - Integrin beta tail domain
  • 0.0001161Direct
    47986,47986
  • 47986 - DEATH domain
  • 47986 - DEATH domain
  • 0.0004849Direct
    57944,56436
  • 57944 - Triple coiled coil domain of C-type lectins
  • 56436 - C-type lectin-like
  • 0.007379Inherited
    47459,55785
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.009101Inherited
    47454,57959
  • 47454 - A DNA-binding domain in eukaryotic transcription factors
  • 57959 - Leucine zipper domain
  • 0.01382Inherited
    57903,47370
  • 57903 - FYVE/PHD zinc finger
  • 47370 - Bromodomain
  • 0.04576Inherited
    55785,55785
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.04937Inherited
    49417,81296
  • 49417 - p53-like transcription factors
  • 81296 - E set domains
  • 0.09885Inherited
    47954,47954
  • 47954 - Cyclin-like
  • 47954 - Cyclin-like
  • 0.09885Inherited
    56436,56436
  • 56436 - C-type lectin-like
  • 56436 - C-type lectin-like
  • 0.1326Inherited
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.1335Inherited
    55550,55550
  • 55550 - SH2 domain
  • 55550 - SH2 domain
  • 0.1772Inherited
    50729,55550
  • 50729 - PH domain-like
  • 55550 - SH2 domain
  • 0.2365Inherited
    48371,56112
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.2365Inherited
    49562,48371
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 0.2365Inherited
    48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 0.388Inherited
    47655,49417
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.388Inherited
    49417,55550
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.388Inherited
    57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.4126Inherited
    57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.5887Inherited
    49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.7168Inherited
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.9893Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57196,57196,69687
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 69687 - Integrin beta tail domain
  • 0.0001161Direct
    47459,55785,55785
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.03039Inherited
    49562,48371,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.2365Inherited
    55550,56112,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 56112 - Protein kinase-like (PK-like)
  • 0.3163Inherited
    50729,55550,56112
  • 50729 - PH domain-like
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.3163Inherited
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.388Inherited
    47655,49417,55550
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.388Inherited
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.5099Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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