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Mammalian Phenotype (MP): abnormal erythroid lineage cell morphology

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + 5:   mammalian phenotype [MP:0000001] <29>
+ + + + 4:   hematopoietic system phenotype [MP:0005397] <2>(72|102) (78|63|30)
+ + + 3:   abnormal hematopoietic system morphology/development [MP:0002396] <5>(59|86) (66|47|21)
+ + 2:   abnormal hematopoietic cell morphology [MP:0013656] <9>(50|77) (60|43|18)
+ 1:   abnormal myeloid cell morphology [MP:0013658] <8>(20|41) (26|23|8)
0:   abnormal erythroid lineage cell morphology [MP:0013659] <5>(8|14) (9|12|6)
- 1:   abnormal erythrocyte morphology [MP:0002447] <30>(6|12) (7|10|4)
- 1:   abnormal erythroid progenitor cell morphology [MP:0008801] <2>(1|1) (1|1|0)
- 1:   abnormal embryonic erythrocyte morphology [MP:0004230] <1>(0|0) (0|0|0)
- 1:   abnormal proerythroblast morphology [MP:0002416] <1>(0|0) (0|0|0)
- 1:   abnormal reticulocyte morphology [MP:0002424] <1>(2|2) (2|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
AraD/HMP-PK domain-like0.001516Inherited
Nucleic acid-binding proteins0.001942Inherited
Cyclin-like0.03065Inherited
BAR/IMD domain-like0.2127Inherited
Transcription factor STAT-4 N-domain0.3707Inherited
STAT0.3707Inherited
p53-like transcription factors0.5392Inherited
Integrin beta tail domain0.5414Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Erythroid transcription factor GATA-10.0003036Direct
DNA replication initiator (cdc21/cdc54) N-terminal domain0.0003036Direct
Noncollagenous (NC1) domain of collagen IV0.0006193Direct
AraD-like aldolase/epimerase0.00102Inherited
Eps15 homology domain (EH domain)0.0079Inherited
Cyclin0.03834Inherited
Hypoxia-inducible factor Hif2a, C-terminal domain0.2382Inherited
Interferons/interleukin-10 (IL-10)0.2382Inherited
STAT0.3407Inherited
STAT DNA-binding domain0.3407Inherited
Transcription factor STAT-4 N-domain0.3407Inherited
Integrin beta EGF-like domains0.5125Inherited
Integrin beta tail domain0.5125Inherited
Short-chain cytokines0.5535Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
AraD/HMP-PK domain-like0.0008494Direct
Nucleic acid-binding proteins0.001101Inherited
Cyclin-like0.0209Inherited
BAR/IMD domain-like0.175Inherited
PH domain-like0.2833Inherited
Transcription factor STAT-4 N-domain0.3249Inherited
STAT0.3249Inherited
p53-like transcription factors0.4922Inherited
Integrin beta tail domain0.4945Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
50729,55550
  • 50729 - PH domain-like
  • 55550 - SH2 domain
  • 0.0005019Direct
    57903,47370
  • 57903 - FYVE/PHD zinc finger
  • 47370 - Bromodomain
  • 0.006683Inherited
    47954,47954
  • 47954 - Cyclin-like
  • 47954 - Cyclin-like
  • 0.03456Inherited
    56436,56436
  • 56436 - C-type lectin-like
  • 56436 - C-type lectin-like
  • 0.05681Inherited
    55785,55785
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.1505Inherited
    57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.241Inherited
    47459,55785
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.276Inherited
    48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 0.3249Inherited
    47655,49417
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.3249Inherited
    49417,55550
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.3249Inherited
    53300,69179
  • 53300 - vWA-like
  • 69179 - Integrin domains
  • 0.4945Inherited
    57196,69687
  • 57196 - EGF/Laminin
  • 69687 - Integrin beta tail domain
  • 0.4945Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    50729,55550,56112
  • 50729 - PH domain-like
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.0008494Direct
    55550,56112,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 56112 - Protein kinase-like (PK-like)
  • 0.0008494Direct
    47459,55785,55785
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.1505Inherited
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.3249Inherited
    47655,49417,55550
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.3249Inherited
    57196,57196,69687
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 69687 - Integrin beta tail domain
  • 0.4945Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)