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Worm Phenotype (WP): slow growth
(show info)
Phenotype Ontology
Like Gene Ontology (GO), phenotypy ontology classifies and organizes gene-mutant/null phenotypic information from the very general at the top to more specific terms in the directed acyclic graph (DAG) by viewing an individual term as a node and its relations to parental terms (allowing for multiple parents) as directed edges. To navigate this hierarchy, we display all parental phenotypic terms to the current phenotypic term of interest ordered by their shortest distances to the current term. Also, only direct children phenotypic terms of the current phenotypic term are listed. Phenotype ontologies we have incorporated are as follows:
- Disease Ontology (DO) Ontology (DO) DO semantically integrates disease and medical vocabularies through extensive cross mapping of DO terms to MeSH, ICD, NCI thesaurus, SNOMED and OMIM.
- Human Phenotype (HP) Ontology (HP) HP captures phenotypic abnormalities that are described in OMIM, along with the corresponding disease-causing genes. It includes three complementary biological concepts: Mode_of_Inheritance (MI), ONset_and_clinical_course (ON), and Phenotypic_Abnormality (PA).
- Mouse Phenotype (MP) Ontology (MP) MP describes phenotypes of the mouse after a specific gene is genetically disrupted. Using it, Mouse Genome Informatics (MGI) provides high-coverate gene-level phenotypes for the mouse.
- Worm Phenotype (WP) Ontology (WP) WP classifies and organizes phenotype descriptions for C. elegans and other nematodes. Using it, WormBase provides primary resource for phenotype annotations for C. elegans.
- Yeast Phenotype (YP) Ontology (YP) Based on YP which is the major contributor to the Ascomycete phenotype ontology, Saccharomyces Genome Database (SGD) provides single mutant phenotypes for every gene in the yeast genome.
- Fly Phenotype (FP) Ontology (FP) FP refers to FlyBase controlled vocabulary. Specifically, a structured controlled vocabulary is used for the annotation of alleles (for their mutagen etc) in FlyBase.
- Fly Anatomy (FA) Ontology (FA) FA is a structured controlled vocabulary of the anatomy of Drosophila melanogaster, used for the description of phenotypes and where a gene is expressed.
- Zebrafish Anatomy (ZA) Ontology (ZA) ZA displays anatomical terms of the zebrafish using standard anatomical nomenclature, together with affected genes.
- Xenopus Anatomy (XA) Ontology (XA) XA represents the lineage of tissues and the timing of development for frogs (Xenopus laevis and Xenopus tropicalis). It is used to annotate Xenopus gene expression patterns and mutant and morphant phenotypes.
- Arabidopsis Plant Ontology (AP) Ontology (AP) As a major contributor to Plant Ontology which describes plant anatomical and morphological structures (AN) and growth and developmental stages (DE), the Arabidopsis Information Resource (TAIR) provides arabidopsis plant ontology annotations for the model higher plant Arabidopsis thaliana.
- Enzyme Commission (EC) Ontology (EC) Each enzyme is allocated a four-digit EC number, the first three digits of which define the reaction catalysed and the fourth of which is a unique identifier (serial number). Each enzyme is also assigned a systematic name that uniquely defines the reaction catalysed.
- DrugBank ATC (DB) Ontology (DB) In the Anatomical Therapeutic Chemical (ATC) classification system, drugs are classified in groups at five different levels according to the organ or system (1st level, anatomical main group) on which they act and their therapeutic (2nd level, therapeutic subgroup), pharmacological (3rd level, pharmacological subgroup) and chemical properties (4th level, chemical subgroup; 5th level, chemical substance). Only drugs in DrugBank are considered.
- UniProtKB KeyWords (KW) Ontology (KW) Keywords in UniProtKB are controlled vocabulary, providing a summary of the entry content and are used to index UniProtKB/Swiss-Prot entries based on 10 categories (the category "Technical term" being excluded here). Each keyword is attributed manually to UniProtKB/Swiss-Prot entries and automatically to UniProtKB/TrEMBL entries (according to specific annotation rules).
- UniProtKB UniPathway (UP) Ontology (UP) UP is a fully manually curated resource for the representation and annotation of metabolic pathways, being used as controlled vocabulary for pathway annotation in UniProtKB.
Structural Domain Phenotype Ontology and its Annotations
Structural Classification of Proteins (SCOP) classifies evolutionary-related domains into Superfamily level and Family level. Using the phenotype ontologies above, we have generated the domain-centric phenotype annotations, and further identified those phenotype terms which are the most informative to annotate SCOP domains. Promisingly, domain-centric phenotypic annotations can serve as an alternative starting point to explore genotype-phenotype relationships. We provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.
- Structural Domain Disease Ontology (DO) Ontology (SDDO) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DO.txt, and the corresponding ontology:SDDO.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Human Phenotype (HP) Ontology (SDHP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2HP.txt, and the corresponding ontology:SDHP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Mouse Phenotype (MP) Ontology (SDMP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2MP.txt, and the corresponding ontology:SDMP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Worm Phenotype (WP) Ontology (SDWP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2WP.txt, and the corresponding ontology:SDWP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Yeast Phenotype (YP) Ontology (SDYP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2YP.txt, and the corresponding ontology:SDYP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Fly Phenotype (FP) Ontology (SDFP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FP.txt, and the corresponding ontology:SDFP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Fly Anatomy (FA) Ontology (SDFA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FA.txt, and the corresponding ontology:SDFA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Zebrafish Anatomy (ZA) Ontology (SDZA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2ZA.txt, and the corresponding ontology:SDZA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Xenopus Anatomy (XA) Ontology (SDXA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2XA.txt, and the corresponding ontology:SDXA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Arabidopsis Plant Ontology (AP) Ontology (SDAP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2AP.txt, and the corresponding ontology:SDAP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Enzyme Commission (EC) Ontology (SDEC) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2EC.txt, and the corresponding ontology:SDEC.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain DrugBank ATC (DB) Ontology (SDDB) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DB.txt, and the corresponding ontology:SDDB.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain UniProtKB KeyWords (KW) Ontology (SDKW) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2KW.txt, and the corresponding ontology:SDKW.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain UniProtKB UniPathway (UP) Ontology (SDUP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2UP.txt, and the corresponding ontology:SDUP.txt) and mysql tables (Domain2PO.sql.gz).
Supra-domain Phenotype Ontology and its Annotations
Although domain-centric annotations hold great promise in describing phenotypic nature of independent domains, most domains themselves may not just work alone. In multi-domain proteins, they may be combined together to form distinct domain architectures. The recombination of the existing domains is considered as one of major driving forces for phenotypic diversificaation. As an extension, we have also generated supra-domain phenotype ontology and its annotations. Compared to domain-centric phenotype ontology and annotations (SCOP domains at the Superfamily level and Family level), this version focuses on supra-domains and individual SCOP domains ONLY at the Superfamily level. Besides, in terms of individual superfamilies, their annotations from the domain-centric version may be different from those from supra-domains version. Depending on your focus, the former should be used for the consideration of both the Superfamily level and Family level, otherwise the latter should be used if you are interested in domain combinations. Also, we provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.
- Supra-domain Domain Disease Ontology (DO) Ontology (SPDO) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DO.txt, and the corresponding ontology:SPDO.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Human Phenotype (HP) Ontology (SPHO) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2HP.txt, and the corresponding ontology:SPHO.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Mouse Phenotype (MP) Ontology (SPMP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2MP.txt, and the corresponding ontology:SPMP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Worm Phenotype (WP) Ontology (SPWP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2WP.txt, and the corresponding ontology:SPWP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Yeast Phenotype (YP) Ontology (SPYP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2YP.txt, and the corresponding ontology:SPYP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Fly Phenotype (FP) Ontology (SPFP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FP.txt, and the corresponding ontology:SPFP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Fly Anatomy (FA) Ontology (SPFA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FA.txt, and the corresponding ontology:SPFA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Zebrafish Anatomy (ZA) Ontology (SPZA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2ZA.txt, and the corresponding ontology:SPZA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Xenopus Anatomy (XA) Ontology (SPXA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2XA.txt, and the corresponding ontology:SPXA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Arabidopsis Plant Ontology (AP) Ontology (SPAP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2AP.txt, and the corresponding ontology:SPAP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Enzyme Commission (EC) Ontology (SPEC) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2EC.txt, and the corresponding ontology:SPEC.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain DrugBank ATC (DB) Ontology (SPDB) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DB.txt, and the corresponding ontology:SPDB.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain UniProtKB KeyWords (KW) Ontology (SPKW) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2KW.txt, and the corresponding ontology:SPKW.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain UniProtKB UniPathway (UP) Ontology (SPUP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2UP.txt, and the corresponding ontology:SPUP.txt) and mysql tables (SP2PO.sql.gz).
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Superfamily(show details)
Superfamily domains annotated to this WP term (Not in SDWP)
Highlighted in gray are those with FDR_all>0.001
SCOP term | FDR (all) | Annotation (direct or inherited) |
FtsH protease domain-like | 0 | DIRECT |
Tubby C-terminal domain-like | 0 | DIRECT |
TK C-terminal domain-like | 0 | DIRECT |
Ribosomal protein L1 | 0 | DIRECT |
RBP11-like subunits of RNA polymerase | 0 | DIRECT |
Ribosomal proteins S24e, L23 and L15e | 0 | DIRECT |
Heme-dependent catalase-like | 0 | DIRECT |
Ferritin-like | 0 | DIRECT |
LysM domain | 0 | DIRECT |
Cystatin/monellin | 0 | DIRECT |
CBD9-like | 0 | DIRECT |
AN1-like Zinc finger | 0 | DIRECT |
MIR domain | 0 | DIRECT |
Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
HRDC-like | 0 | DIRECT |
Carbohydrate phosphatase | 0 | DIRECT |
ADP-ribosylation | 0 | DIRECT |
SAND domain-like | 0 | DIRECT |
ArfGap/RecO-like zinc finger | 0 | DIRECT |
R3H domain | 0 | DIRECT |
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0 | DIRECT |
Nucleoside diphosphate kinase, NDK | 0 | DIRECT |
PGBD-like | 0 | DIRECT |
Transducin (alpha subunit), insertion domain | 0 | DIRECT |
ALDH-like | 0 | DIRECT |
Proton glutamate symport protein | 0 | DIRECT |
Cation efflux protein cytoplasmic domain-like | 0 | DIRECT |
Mitochondrial carrier | 0 | DIRECT |
PurM N-terminal domain-like | 0 | DIRECT |
Thiamin diphosphate-binding fold (THDP-binding) | 0 | DIRECT |
Galactose oxidase, central domain | 0 | DIRECT |
MgtE membrane domain-like | 0 | DIRECT |
CO dehydrogenase molybdoprotein N-domain-like | 0 | DIRECT |
HSP90 C-terminal domain | 0 | DIRECT |
WGR domain-like | 0 | DIRECT |
CRAL/TRIO N-terminal domain | 0 | DIRECT |
Doublecortin (DC) | 0 | DIRECT |
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | DIRECT |
eIF4e-like | 0 | DIRECT |
Citrate synthase | 0 | DIRECT |
DNA repair protein MutS, domain III | 0 | DIRECT |
Oxysterol-binding protein-like | 0 | DIRECT |
Aminoacid dehydrogenase-like, N-terminal domain | 0 | DIRECT |
LEM domain | 0 | DIRECT |
PHM/PNGase F | 0 | DIRECT |
PreATP-grasp domain | 0 | DIRECT |
5' to 3' exonuclease, C-terminal subdomain | 0 | DIRECT |
PK beta-barrel domain-like | 0 | DIRECT |
Phoshotransferase/anion transport protein | 0 | DIRECT |
VPS9 domain | 0 | DIRECT |
Creatinase/prolidase N-terminal domain | 0 | DIRECT |
Surp module (SWAP domain) | 0 | DIRECT |
Complement control module/SCR domain | 0 | DIRECT |
SWIB/MDM2 domain | 0 | DIRECT |
SPOC domain-like | 0 | DIRECT |
FAD-linked oxidases, C-terminal domain | 0 | DIRECT |
Rap/Ran-GAP | 0 | DIRECT |
YWTD domain | 0 | DIRECT |
S-adenosylmethionine synthetase | 0 | DIRECT |
YbiA-like | 0 | DIRECT |
Single hybrid motif | 0 | DIRECT |
Nucleoporin domain | 0 | DIRECT |
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
MFPT repeat-like | 0 | DIRECT |
GAS2 domain-like | 0 | DIRECT |
Terpenoid cyclases/Protein prenyltransferases | 0 | DIRECT |
PEP carboxykinase N-terminal domain | 0 | DIRECT |
Tricorn protease domain 2 | 0 | DIRECT |
Hormone receptor domain | 0 | DIRECT |
ARID-like | 0 | DIRECT |
Isocitrate/Isopropylmalate dehydrogenase-like | 0 | DIRECT |
Transducin (heterotrimeric G protein), gamma chain | 0 | DIRECT |
alpha/beta knot | 0 | DIRECT |
Sec63 N-terminal domain-like | 0 | DIRECT |
Phosphoenolpyruvate/pyruvate domain | 0 | DIRECT |
LDH C-terminal domain-like | 0 | DIRECT |
N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
Cytochrome c | 0 | DIRECT |
Blood coagulation inhibitor (disintegrin) | 0 | DIRECT |
Pepsin inhibitor-3 | 0 | DIRECT |
Small-conductance potassium channel | 0 | DIRECT |
Hypothetical protein c14orf129, hspc210 | 0 | DIRECT |
Cdc48 domain 2-like | 0 | DIRECT |
Thyroglobulin type-1 domain | 0 | DIRECT |
PABC (PABP) domain | 0 | DIRECT |
Restriction endonuclease-like | 0 | DIRECT |
Chitinase insertion domain | 0 | DIRECT |
Ran binding protein zinc finger-like | 0 | DIRECT |
Cu,Zn superoxide dismutase-like | 0 | DIRECT |
Radical SAM enzymes | 0 | DIRECT |
Ribosomal protein L10-like | 0 | DIRECT |
Glycolipid transfer protein, GLTP | 0 | DIRECT |
Bacterial exopeptidase dimerisation domain | 0 | DIRECT |
Ribulose-phoshate binding barrel | 0 | DIRECT |
Annexin | 0 | DIRECT |
Class II aaRS ABD-related | 0 | DIRECT |
PEBP-like | 0 | DIRECT |
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | DIRECT |
Pentein | 0 | DIRECT |
FAD-binding/transporter-associated domain-like | 0 | DIRECT |
Hedgehog/intein (Hint) domain | 0 | DIRECT |
PurM C-terminal domain-like | 0 | DIRECT |
Ribosomal protein S10 | 0 | DIRECT |
Molybdenum cofactor-binding domain | 0 | DIRECT |
C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
Domain of poly(ADP-ribose) polymerase | 0 | DIRECT |
Fibrinogen C-terminal domain-like | 0 | DIRECT |
GYF domain | 0 | DIRECT |
Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
Zn-binding ribosomal proteins | 0 | DIRECT |
Acid phosphatase/Vanadium-dependent haloperoxidase | 0 | DIRECT |
PEP carboxykinase-like | 0 | DIRECT |
TGS-like | 0 | DIRECT |
Diaminopimelate epimerase-like | 0 | DIRECT |
Troponin coil-coiled subunits | 0 | DIRECT |
MOSC N-terminal domain-like | 0 | DIRECT |
FF domain | 0 | DIRECT |
Ribokinase-like | 0 | DIRECT |
ThrRS/AlaRS common domain | 0 | DIRECT |
CO dehydrogenase ISP C-domain like | 0 | DIRECT |
Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | DIRECT |
Translational machinery components | 0 | DIRECT |
Rudiment single hybrid motif | 0 | DIRECT |
L-aspartase-like | 0 | DIRECT |
Outer arm dynein light chain 1 | 0 | DIRECT |
ValRS/IleRS/LeuRS editing domain | 0 | DIRECT |
Elafin-like | 0 | DIRECT |
Cadherin-like | 0 | DIRECT |
Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | DIRECT |
PapD-like | 0.0004042 | DIRECT |
SCOP term | FDR (all) | Annotation (direct or inherited) |
FtsH protease domain-like | 0 | Direct |
Tubby C-terminal domain-like | 0 | Direct |
TK C-terminal domain-like | 0 | Direct |
Ribosomal protein L1 | 0 | Direct |
RBP11-like subunits of RNA polymerase | 0 | Direct |
Ribosomal proteins S24e, L23 and L15e | 0 | Direct |
Heme-dependent catalase-like | 0 | Direct |
Ferritin-like | 0 | Direct |
LysM domain | 0 | Direct |
Cystatin/monellin | 0 | Direct |
CBD9-like | 0 | Direct |
AN1-like Zinc finger | 0 | Direct |
MIR domain | 0 | Direct |
Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
HRDC-like | 0 | Direct |
Carbohydrate phosphatase | 0 | Direct |
ADP-ribosylation | 0 | Direct |
SAND domain-like | 0 | Direct |
ArfGap/RecO-like zinc finger | 0 | Direct |
R3H domain | 0 | Direct |
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0 | Direct |
Nucleoside diphosphate kinase, NDK | 0 | Direct |
PGBD-like | 0 | Direct |
Transducin (alpha subunit), insertion domain | 0 | Direct |
ALDH-like | 0 | Direct |
Proton glutamate symport protein | 0 | Direct |
Cation efflux protein cytoplasmic domain-like | 0 | Direct |
Mitochondrial carrier | 0 | Direct |
PurM N-terminal domain-like | 0 | Direct |
Thiamin diphosphate-binding fold (THDP-binding) | 0 | Direct |
Galactose oxidase, central domain | 0 | Direct |
MgtE membrane domain-like | 0 | Direct |
CO dehydrogenase molybdoprotein N-domain-like | 0 | Direct |
HSP90 C-terminal domain | 0 | Direct |
WGR domain-like | 0 | Direct |
CRAL/TRIO N-terminal domain | 0 | Direct |
Doublecortin (DC) | 0 | Direct |
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | Direct |
eIF4e-like | 0 | Direct |
Citrate synthase | 0 | Direct |
DNA repair protein MutS, domain III | 0 | Direct |
Oxysterol-binding protein-like | 0 | Direct |
Aminoacid dehydrogenase-like, N-terminal domain | 0 | Direct |
LEM domain | 0 | Direct |
PHM/PNGase F | 0 | Direct |
PreATP-grasp domain | 0 | Direct |
5' to 3' exonuclease, C-terminal subdomain | 0 | Direct |
PK beta-barrel domain-like | 0 | Direct |
Phoshotransferase/anion transport protein | 0 | Direct |
VPS9 domain | 0 | Direct |
Creatinase/prolidase N-terminal domain | 0 | Direct |
Surp module (SWAP domain) | 0 | Direct |
Complement control module/SCR domain | 0 | Direct |
SWIB/MDM2 domain | 0 | Direct |
SPOC domain-like | 0 | Direct |
FAD-linked oxidases, C-terminal domain | 0 | Direct |
Rap/Ran-GAP | 0 | Direct |
YWTD domain | 0 | Direct |
S-adenosylmethionine synthetase | 0 | Direct |
YbiA-like | 0 | Direct |
Single hybrid motif | 0 | Direct |
Nucleoporin domain | 0 | Direct |
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
MFPT repeat-like | 0 | Direct |
GAS2 domain-like | 0 | Direct |
Terpenoid cyclases/Protein prenyltransferases | 0 | Direct |
PEP carboxykinase N-terminal domain | 0 | Direct |
Tricorn protease domain 2 | 0 | Direct |
Hormone receptor domain | 0 | Direct |
ARID-like | 0 | Direct |
Isocitrate/Isopropylmalate dehydrogenase-like | 0 | Direct |
Transducin (heterotrimeric G protein), gamma chain | 0 | Direct |
alpha/beta knot | 0 | Direct |
Sec63 N-terminal domain-like | 0 | Direct |
Phosphoenolpyruvate/pyruvate domain | 0 | Direct |
LDH C-terminal domain-like | 0 | Direct |
N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
Cytochrome c | 0 | Direct |
Blood coagulation inhibitor (disintegrin) | 0 | Direct |
Pepsin inhibitor-3 | 0 | Direct |
Small-conductance potassium channel | 0 | Direct |
Hypothetical protein c14orf129, hspc210 | 0 | Direct |
Cdc48 domain 2-like | 0 | Direct |
Thyroglobulin type-1 domain | 0 | Direct |
PABC (PABP) domain | 0 | Direct |
Restriction endonuclease-like | 0 | Direct |
Chitinase insertion domain | 0 | Direct |
Ran binding protein zinc finger-like | 0 | Direct |
Cu,Zn superoxide dismutase-like | 0 | Direct |
Radical SAM enzymes | 0 | Direct |
Ribosomal protein L10-like | 0 | Direct |
Glycolipid transfer protein, GLTP | 0 | Direct |
Bacterial exopeptidase dimerisation domain | 0 | Direct |
Ribulose-phoshate binding barrel | 0 | Direct |
Annexin | 0 | Direct |
Class II aaRS ABD-related | 0 | Direct |
PEBP-like | 0 | Direct |
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | Direct |
Pentein | 0 | Direct |
FAD-binding/transporter-associated domain-like | 0 | Direct |
Hedgehog/intein (Hint) domain | 0 | Direct |
PurM C-terminal domain-like | 0 | Direct |
Ribosomal protein S10 | 0 | Direct |
Molybdenum cofactor-binding domain | 0 | Direct |
C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
Domain of poly(ADP-ribose) polymerase | 0 | Direct |
Fibrinogen C-terminal domain-like | 0 | Direct |
GYF domain | 0 | Direct |
Composite domain of metallo-dependent hydrolases | 0 | Direct |
Zn-binding ribosomal proteins | 0 | Direct |
Acid phosphatase/Vanadium-dependent haloperoxidase | 0 | Direct |
PEP carboxykinase-like | 0 | Direct |
TGS-like | 0 | Direct |
Diaminopimelate epimerase-like | 0 | Direct |
Troponin coil-coiled subunits | 0 | Direct |
MOSC N-terminal domain-like | 0 | Direct |
FF domain | 0 | Direct |
Ribokinase-like | 0 | Direct |
ThrRS/AlaRS common domain | 0 | Direct |
CO dehydrogenase ISP C-domain like | 0 | Direct |
Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | Direct |
Translational machinery components | 0 | Direct |
Rudiment single hybrid motif | 0 | Direct |
L-aspartase-like | 0 | Direct |
Outer arm dynein light chain 1 | 0 | Direct |
ValRS/IleRS/LeuRS editing domain | 0 | Direct |
Elafin-like | 0 | Direct |
Cadherin-like | 0 | Direct |
Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | Direct |
PapD-like | 0.0004042 | Direct |
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Family(show details)
Family domains annotated to this WP term (SDWP level: Least Informative)
Highlighted in gray are those with FDR_all>0.001
SCOP term | FDR (all) | Annotation (direct or inherited) |
Ribosomal protein S10 | 0 | DIRECT |
Transducin (heterotrimeric G protein), gamma chain | 0 | DIRECT |
Ubiquitin carboxyl-terminal hydrolase UCH-L | 0 | DIRECT |
XPF/Rad1/Mus81 nuclease | 0 | DIRECT |
Serum paraoxonase/arylesterase 1, PON1 | 0 | DIRECT |
Troponin I | 0 | DIRECT |
Matrix metalloproteases, catalytic domain | 0 | DIRECT |
COMT-like | 0 | DIRECT |
Type II chitinase | 0 | DIRECT |
N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
Glycosyl transferases group 1 | 0 | DIRECT |
YihX-like | 0 | DIRECT |
Domain of poly(ADP-ribose) polymerase | 0 | DIRECT |
Protein prenyltransferases | 0 | DIRECT |
C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
VHS domain | 0 | DIRECT |
GYF domain | 0 | DIRECT |
AMPK-beta glycogen binding domain-like | 0 | DIRECT |
D-aminoacid oxidase-like | 0 | DIRECT |
ALDH-like | 0 | DIRECT |
ValRS/IleRS/LeuRS editing domain | 0 | DIRECT |
Hydantoinase (dihydropyrimidinase), catalytic domain | 0 | DIRECT |
Hexokinase | 0 | DIRECT |
Oxysterol-binding protein | 0 | DIRECT |
DPP6 catalytic domain-like | 0 | DIRECT |
5' to 3' exonuclease catalytic domain | 0 | DIRECT |
Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
Hypothetical protein c14orf129, hspc210 | 0 | DIRECT |
CO dehydrogenase flavoprotein N-terminal domain-like | 0 | DIRECT |
Gamma-glutamyltranspeptidase-like | 0 | DIRECT |
LysM domain | 0 | DIRECT |
Chitinase insertion domain | 0 | DIRECT |
Ran binding protein zinc finger-like | 0 | DIRECT |
Brix domain | 0 | DIRECT |
Mitochondrial carrier | 0 | DIRECT |
NHL repeat | 0 | DIRECT |
Inositol monophosphatase/fructose-1,6-bisphosphatase-like | 0 | DIRECT |
Ribosomal protein L18 and S11 | 0 | DIRECT |
SAM (sterile alpha motif) domain | 0 | DIRECT |
Thyroglobulin type-1 domain | 0 | DIRECT |
Ribokinase-like | 0 | DIRECT |
Poly(ADP-ribose) polymerase, C-terminal domain | 0 | DIRECT |
HSP90 C-terminal domain | 0 | DIRECT |
Hsp90 middle domain | 0 | DIRECT |
GAS2 domain | 0 | DIRECT |
Lactate & malate dehydrogenases, C-terminal domain | 0 | DIRECT |
Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | DIRECT |
PurM C-terminal domain-like | 0 | DIRECT |
CoA-binding domain | 0 | DIRECT |
NOL1/NOP2/sun | 0 | DIRECT |
PEP carboxykinase N-terminal domain | 0 | DIRECT |
IF2B-like | 0 | DIRECT |
Cytoplasmic domain of inward rectifier potassium channel | 0 | DIRECT |
LEM domain | 0 | DIRECT |
Choline kinase | 0 | DIRECT |
DEP domain | 0 | DIRECT |
Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain | 0 | DIRECT |
Citrate synthase | 0 | DIRECT |
Phosphatidylethanolamine binding protein | 0 | DIRECT |
RhoGDI-like | 0 | DIRECT |
Hedgehog C-terminal (Hog) autoprocessing domain | 0 | DIRECT |
Vertebrate phospholipase A2 | 0 | DIRECT |
Sec63 N-terminal domain | 0 | DIRECT |
SWIRM domain | 0 | DIRECT |
Translation initiation factor eIF4e | 0 | DIRECT |
Tetraspanin | 0 | DIRECT |
Calpain large subunit, catalytic domain (domain II) | 0 | DIRECT |
PUA domain | 0 | DIRECT |
alpha-Amylases, C-terminal beta-sheet domain | 0 | DIRECT |
Doublecortin (DC) | 0 | DIRECT |
DNA repair protein MutS, domain III | 0 | DIRECT |
UBA domain | 0 | DIRECT |
Myotubularin-like phosphatases | 0 | DIRECT |
acyl-CoA oxidase C-terminal domains | 0 | DIRECT |
CRAL/TRIO N-terminal domain | 0 | DIRECT |
Rap/Ran-GAP | 0 | DIRECT |
Regulator of chromosome condensation RCC1 | 0 | DIRECT |
Surp module (SWAP domain) | 0 | DIRECT |
PhzC/PhzF-like | 0 | DIRECT |
Fibrinogen C-terminal domain-like | 0 | DIRECT |
Arylsulfatase | 0 | DIRECT |
SAND domain | 0 | DIRECT |
Nucleoside diphosphate kinase, NDK | 0 | DIRECT |
HD domain | 0 | DIRECT |
WGR domain | 0 | DIRECT |
Pyk2-associated protein beta ARF-GAP domain | 0 | DIRECT |
Glycogenin | 0 | DIRECT |
Glycolipid transfer protein, GLTP | 0 | DIRECT |
Pepsin inhibitor-3 | 0 | DIRECT |
Cdc48 domain 2-like | 0 | DIRECT |
Heat shock protein 90, HSP90, N-terminal domain | 0 | DIRECT |
CAT-like | 0 | DIRECT |
Hydantoinase (dihydropyrimidinase) | 0 | DIRECT |
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | DIRECT |
Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain | 0 | DIRECT |
FAD-dependent thiol oxidase | 0 | DIRECT |
DEATH domain, DD | 0 | DIRECT |
Annexin | 0 | DIRECT |
Cadherin | 0 | DIRECT |
Sec63 C-terminal domain-like | 0 | DIRECT |
Ribosomal protein L1 | 0 | DIRECT |
D-aminoacid oxidase, N-terminal domain | 0 | DIRECT |
Peptidylglycine alpha-hydroxylating monooxygenase, PHM | 0 | DIRECT |
MOSC N-terminal domain-like | 0 | DIRECT |
a tRNA synthase domain | 0 | DIRECT |
5' to 3' exonuclease, C-terminal subdomain | 0 | DIRECT |
PABC (PABP) domain | 0 | DIRECT |
Inositol polyphosphate 5-phosphatase (IPP5) | 0 | DIRECT |
Bactericidal permeability-increasing protein, BPI | 0 | DIRECT |
Branched-chain alpha-keto acid dehydrogenase Pyr module | 0 | DIRECT |
Elafin-like | 0 | DIRECT |
Biotinyl/lipoyl-carrier proteins and domains | 0 | DIRECT |
AN1-like Zinc finger | 0 | DIRECT |
Aminoacid dehydrogenase-like, C-terminal domain | 0 | DIRECT |
Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | DIRECT |
GAPDH-like | 0 | DIRECT |
1,3-glucuronyltransferase | 0 | DIRECT |
Class I glutamine amidotransferases (GAT) | 0 | DIRECT |
Phoshoinositide 3-kinase (PI3K) helical domain | 0 | DIRECT |
Molybdenum cofactor-binding domain | 0 | DIRECT |
ATP-dependent protease Lon (La), catalytic domain | 0 | DIRECT |
UDP-glucose pyrophosphorylase | 0 | DIRECT |
Biotin dependent carboxylase carboxyltransferase domain | 0 | DIRECT |
Ras-binding domain, RBD | 0 | DIRECT |
Acyl-CoA thioesterase | 0 | DIRECT |
CO dehydrogenase ISP C-domain like | 0 | DIRECT |
Acireductone dioxygenase | 0 | DIRECT |
LacY-like proton/sugar symporter | 0 | DIRECT |
Lesion bypass DNA polymerase (Y-family), catalytic domain | 0 | DIRECT |
Pancreatic carboxypeptidase, activation domain | 0 | DIRECT |
Blood coagulation inhibitor (disintegrin) | 0 | DIRECT |
RNA-polymerase beta | 0 | DIRECT |
S-adenosylmethionine synthetase | 0 | DIRECT |
Branched-chain alpha-keto acid dehydrogenase PP module | 0 | DIRECT |
Transducin (alpha subunit), insertion domain | 0 | DIRECT |
HCDH C-domain-like | 0 | DIRECT |
28-residue LRR | 0 | DIRECT |
FtsH protease domain-like | 0 | DIRECT |
SWIB/MDM2 domain | 0 | DIRECT |
MFPT repeat | 0 | DIRECT |
BC N-terminal domain-like | 0 | DIRECT |
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
MIR domain | 0 | DIRECT |
Small-conductance potassium channel | 0 | DIRECT |
Cation efflux protein cytoplasmic domain-like | 0 | DIRECT |
Arfaptin, Rac-binding fragment | 0 | DIRECT |
BC C-terminal domain-like | 0 | DIRECT |
YbiA-like | 0 | DIRECT |
Glycerol kinase | 0 | DIRECT |
PurM N-terminal domain-like | 0 | DIRECT |
L-aminoacid/polyamine oxidase | 0 | DIRECT |
BC ATP-binding domain-like | 0 | DIRECT |
DPP6 N-terminal domain-like | 0 | DIRECT |
Acylamino-acid-releasing enzyme, C-terminal donain | 0 | DIRECT |
Glycerophosphoryl diester phosphodiesterase | 0 | DIRECT |
Dimeric isocitrate & isopropylmalate dehydrogenases | 0 | DIRECT |
Methionine aminopeptidase, insert domain | 0 | DIRECT |
Anticodon-binding domain | 0 | DIRECT |
Chromo domain | 0 | DIRECT |
FF domain | 0 | DIRECT |
Anticodon-binding domain of Class II aaRS | 0 | DIRECT |
Arginine methyltransferase | 0 | DIRECT |
Amylase, catalytic domain | 0 | DIRECT |
PEP carboxykinase C-terminal domain | 0 | DIRECT |
First domain of FERM | 0 | DIRECT |
Hormone receptor domain | 0 | DIRECT |
ARID domain | 0 | DIRECT |
CO dehydrogenase molybdoprotein N-domain-like | 0 | DIRECT |
La domain | 0 | DIRECT |
Adenain-like | 0 | DIRECT |
Heme-dependent catalases | 0 | DIRECT |
Epoxide hydrolase | 0 | DIRECT |
2Fe-2S ferredoxin domains from multidomain proteins | 0 | DIRECT |
LDH N-terminal domain-like | 0 | DIRECT |
Inositol polyphosphate kinase (IPK) | 0 | DIRECT |
YWTD domain | 0 | DIRECT |
Cu,Zn superoxide dismutase-like | 0 | DIRECT |
Complement control module/SCR domain | 0 | DIRECT |
Cell cycle control phosphatase, catalytic domain | 0 | DIRECT |
Glutaminase | 0 | DIRECT |
Proton glutamate symport protein | 0 | DIRECT |
Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain | 0 | DIRECT |
Bacterial exopeptidase dimerisation domain | 0 | DIRECT |
acyl-CoA oxidase N-terminal domains | 0 | DIRECT |
SCOP term | FDR (all) | Annotation (direct or inherited) |
Ribosomal protein S10 | 0 | Direct |
Transducin (heterotrimeric G protein), gamma chain | 0 | Direct |
Ubiquitin carboxyl-terminal hydrolase UCH-L | 0 | Direct |
XPF/Rad1/Mus81 nuclease | 0 | Direct |
Serum paraoxonase/arylesterase 1, PON1 | 0 | Direct |
Troponin I | 0 | Direct |
Matrix metalloproteases, catalytic domain | 0 | Direct |
COMT-like | 0 | Direct |
Type II chitinase | 0 | Direct |
N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
Glycosyl transferases group 1 | 0 | Direct |
YihX-like | 0 | Direct |
Domain of poly(ADP-ribose) polymerase | 0 | Direct |
Protein prenyltransferases | 0 | Direct |
C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
VHS domain | 0 | Direct |
GYF domain | 0 | Direct |
AMPK-beta glycogen binding domain-like | 0 | Direct |
D-aminoacid oxidase-like | 0 | Direct |
ALDH-like | 0 | Direct |
ValRS/IleRS/LeuRS editing domain | 0 | Direct |
Hydantoinase (dihydropyrimidinase), catalytic domain | 0 | Direct |
Hexokinase | 0 | Direct |
Oxysterol-binding protein | 0 | Direct |
DPP6 catalytic domain-like | 0 | Direct |
5' to 3' exonuclease catalytic domain | 0 | Direct |
Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
Hypothetical protein c14orf129, hspc210 | 0 | Direct |
CO dehydrogenase flavoprotein N-terminal domain-like | 0 | Direct |
Gamma-glutamyltranspeptidase-like | 0 | Direct |
LysM domain | 0 | Direct |
Chitinase insertion domain | 0 | Direct |
Ran binding protein zinc finger-like | 0 | Direct |
Brix domain | 0 | Direct |
Mitochondrial carrier | 0 | Direct |
NHL repeat | 0 | Direct |
Inositol monophosphatase/fructose-1,6-bisphosphatase-like | 0 | Direct |
Ribosomal protein L18 and S11 | 0 | Direct |
SAM (sterile alpha motif) domain | 0 | Direct |
Thyroglobulin type-1 domain | 0 | Direct |
Ribokinase-like | 0 | Direct |
Poly(ADP-ribose) polymerase, C-terminal domain | 0 | Direct |
HSP90 C-terminal domain | 0 | Direct |
Hsp90 middle domain | 0 | Direct |
GAS2 domain | 0 | Direct |
Lactate & malate dehydrogenases, C-terminal domain | 0 | Direct |
Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | Direct |
PurM C-terminal domain-like | 0 | Direct |
CoA-binding domain | 0 | Direct |
NOL1/NOP2/sun | 0 | Direct |
PEP carboxykinase N-terminal domain | 0 | Direct |
IF2B-like | 0 | Direct |
Cytoplasmic domain of inward rectifier potassium channel | 0 | Direct |
LEM domain | 0 | Direct |
Choline kinase | 0 | Direct |
DEP domain | 0 | Direct |
Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain | 0 | Direct |
Citrate synthase | 0 | Direct |
Phosphatidylethanolamine binding protein | 0 | Direct |
RhoGDI-like | 0 | Direct |
Hedgehog C-terminal (Hog) autoprocessing domain | 0 | Direct |
Vertebrate phospholipase A2 | 0 | Direct |
Sec63 N-terminal domain | 0 | Direct |
SWIRM domain | 0 | Direct |
Translation initiation factor eIF4e | 0 | Direct |
Tetraspanin | 0 | Direct |
Calpain large subunit, catalytic domain (domain II) | 0 | Direct |
PUA domain | 0 | Direct |
alpha-Amylases, C-terminal beta-sheet domain | 0 | Direct |
Doublecortin (DC) | 0 | Direct |
DNA repair protein MutS, domain III | 0 | Direct |
UBA domain | 0 | Direct |
Myotubularin-like phosphatases | 0 | Direct |
acyl-CoA oxidase C-terminal domains | 0 | Direct |
CRAL/TRIO N-terminal domain | 0 | Direct |
Rap/Ran-GAP | 0 | Direct |
Regulator of chromosome condensation RCC1 | 0 | Direct |
Surp module (SWAP domain) | 0 | Direct |
PhzC/PhzF-like | 0 | Direct |
Fibrinogen C-terminal domain-like | 0 | Direct |
Arylsulfatase | 0 | Direct |
SAND domain | 0 | Direct |
Nucleoside diphosphate kinase, NDK | 0 | Direct |
HD domain | 0 | Direct |
WGR domain | 0 | Direct |
Pyk2-associated protein beta ARF-GAP domain | 0 | Direct |
Glycogenin | 0 | Direct |
Glycolipid transfer protein, GLTP | 0 | Direct |
Pepsin inhibitor-3 | 0 | Direct |
Cdc48 domain 2-like | 0 | Direct |
Heat shock protein 90, HSP90, N-terminal domain | 0 | Direct |
CAT-like | 0 | Direct |
Hydantoinase (dihydropyrimidinase) | 0 | Direct |
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | Direct |
Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain | 0 | Direct |
FAD-dependent thiol oxidase | 0 | Direct |
DEATH domain, DD | 0 | Direct |
Annexin | 0 | Direct |
Cadherin | 0 | Direct |
Sec63 C-terminal domain-like | 0 | Direct |
Ribosomal protein L1 | 0 | Direct |
D-aminoacid oxidase, N-terminal domain | 0 | Direct |
Peptidylglycine alpha-hydroxylating monooxygenase, PHM | 0 | Direct |
MOSC N-terminal domain-like | 0 | Direct |
a tRNA synthase domain | 0 | Direct |
5' to 3' exonuclease, C-terminal subdomain | 0 | Direct |
PABC (PABP) domain | 0 | Direct |
Inositol polyphosphate 5-phosphatase (IPP5) | 0 | Direct |
Bactericidal permeability-increasing protein, BPI | 0 | Direct |
Branched-chain alpha-keto acid dehydrogenase Pyr module | 0 | Direct |
Elafin-like | 0 | Direct |
Biotinyl/lipoyl-carrier proteins and domains | 0 | Direct |
AN1-like Zinc finger | 0 | Direct |
Aminoacid dehydrogenase-like, C-terminal domain | 0 | Direct |
Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | Direct |
GAPDH-like | 0 | Direct |
1,3-glucuronyltransferase | 0 | Direct |
Class I glutamine amidotransferases (GAT) | 0 | Direct |
Phoshoinositide 3-kinase (PI3K) helical domain | 0 | Direct |
Molybdenum cofactor-binding domain | 0 | Direct |
ATP-dependent protease Lon (La), catalytic domain | 0 | Direct |
UDP-glucose pyrophosphorylase | 0 | Direct |
Biotin dependent carboxylase carboxyltransferase domain | 0 | Direct |
Ras-binding domain, RBD | 0 | Direct |
Acyl-CoA thioesterase | 0 | Direct |
CO dehydrogenase ISP C-domain like | 0 | Direct |
Acireductone dioxygenase | 0 | Direct |
LacY-like proton/sugar symporter | 0 | Direct |
Lesion bypass DNA polymerase (Y-family), catalytic domain | 0 | Direct |
Pancreatic carboxypeptidase, activation domain | 0 | Direct |
Blood coagulation inhibitor (disintegrin) | 0 | Direct |
RNA-polymerase beta | 0 | Direct |
S-adenosylmethionine synthetase | 0 | Direct |
Branched-chain alpha-keto acid dehydrogenase PP module | 0 | Direct |
Transducin (alpha subunit), insertion domain | 0 | Direct |
HCDH C-domain-like | 0 | Direct |
28-residue LRR | 0 | Direct |
FtsH protease domain-like | 0 | Direct |
SWIB/MDM2 domain | 0 | Direct |
MFPT repeat | 0 | Direct |
BC N-terminal domain-like | 0 | Direct |
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
MIR domain | 0 | Direct |
Small-conductance potassium channel | 0 | Direct |
Cation efflux protein cytoplasmic domain-like | 0 | Direct |
Arfaptin, Rac-binding fragment | 0 | Direct |
BC C-terminal domain-like | 0 | Direct |
YbiA-like | 0 | Direct |
Glycerol kinase | 0 | Direct |
PurM N-terminal domain-like | 0 | Direct |
L-aminoacid/polyamine oxidase | 0 | Direct |
BC ATP-binding domain-like | 0 | Direct |
DPP6 N-terminal domain-like | 0 | Direct |
Acylamino-acid-releasing enzyme, C-terminal donain | 0 | Direct |
Glycerophosphoryl diester phosphodiesterase | 0 | Direct |
Dimeric isocitrate & isopropylmalate dehydrogenases | 0 | Direct |
Methionine aminopeptidase, insert domain | 0 | Direct |
Anticodon-binding domain | 0 | Direct |
Chromo domain | 0 | Direct |
FF domain | 0 | Direct |
Anticodon-binding domain of Class II aaRS | 0 | Direct |
Arginine methyltransferase | 0 | Direct |
Amylase, catalytic domain | 0 | Direct |
PEP carboxykinase C-terminal domain | 0 | Direct |
First domain of FERM | 0 | Direct |
Hormone receptor domain | 0 | Direct |
ARID domain | 0 | Direct |
CO dehydrogenase molybdoprotein N-domain-like | 0 | Direct |
La domain | 0 | Direct |
Adenain-like | 0 | Direct |
Heme-dependent catalases | 0 | Direct |
Epoxide hydrolase | 0 | Direct |
2Fe-2S ferredoxin domains from multidomain proteins | 0 | Direct |
LDH N-terminal domain-like | 0 | Direct |
Inositol polyphosphate kinase (IPK) | 0 | Direct |
YWTD domain | 0 | Direct |
Cu,Zn superoxide dismutase-like | 0 | Direct |
Complement control module/SCR domain | 0 | Direct |
Cell cycle control phosphatase, catalytic domain | 0 | Direct |
Glutaminase | 0 | Direct |
Proton glutamate symport protein | 0 | Direct |
Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain | 0 | Direct |
Bacterial exopeptidase dimerisation domain | 0 | Direct |
acyl-CoA oxidase N-terminal domains | 0 | Direct |
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Supra-domain (including individual superfamily)
(show details)
Supra-domains annotated to this WP term (Not in SPWP)
Highlighted in gray are those with FDR>0.001
Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
Radical SAM enzymes | 0 | DIRECT |
Cadherin-like | 0 | DIRECT |
5' to 3' exonuclease, C-terminal subdomain | 0 | DIRECT |
AN1-like Zinc finger | 0 | DIRECT |
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | DIRECT |
Hormone receptor domain | 0 | DIRECT |
PEP carboxykinase N-terminal domain | 0 | DIRECT |
FF domain | 0 | DIRECT |
C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
Nucleoside diphosphate kinase, NDK | 0 | DIRECT |
Zn-binding ribosomal proteins | 0 | DIRECT |
Tricorn protease domain 2 | 0 | DIRECT |
Phosphoenolpyruvate/pyruvate domain | 0 | DIRECT |
Ribokinase-like | 0 | DIRECT |
Surp module (SWAP domain) | 0 | DIRECT |
Cdc48 domain 2-like | 0 | DIRECT |
Ribulose-phoshate binding barrel | 0 | DIRECT |
ArfGap/RecO-like zinc finger | 0 | DIRECT |
MIR domain | 0 | DIRECT |
Hedgehog/intein (Hint) domain | 0 | DIRECT |
TK C-terminal domain-like | 0 | DIRECT |
ADP-ribosylation | 0 | DIRECT |
LDH C-terminal domain-like | 0 | DIRECT |
Single hybrid motif | 0 | DIRECT |
Galactose oxidase, central domain | 0 | DIRECT |
Ribosomal protein L1 | 0 | DIRECT |
PGBD-like | 0 | DIRECT |
MgtE membrane domain-like | 0 | DIRECT |
Ribosomal protein S10 | 0 | DIRECT |
Ferritin-like | 0 | DIRECT |
Tubby C-terminal domain-like | 0 | DIRECT |
Restriction endonuclease-like | 0 | DIRECT |
SWIB/MDM2 domain | 0 | DIRECT |
Cu,Zn superoxide dismutase-like | 0 | DIRECT |
Chitinase insertion domain | 0 | DIRECT |
Oxysterol-binding protein-like | 0 | DIRECT |
N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
MOSC N-terminal domain-like | 0 | DIRECT |
PHM/PNGase F | 0 | DIRECT |
PABC (PABP) domain | 0 | DIRECT |
Phoshotransferase/anion transport protein | 0 | DIRECT |
SAND domain-like | 0 | DIRECT |
Ran binding protein zinc finger-like | 0 | DIRECT |
FtsH protease domain-like | 0 | DIRECT |
ALDH-like | 0 | DIRECT |
PurM N-terminal domain-like | 0 | DIRECT |
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | DIRECT |
HSP90 C-terminal domain | 0 | DIRECT |
LysM domain | 0 | DIRECT |
PreATP-grasp domain | 0 | DIRECT |
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
Thyroglobulin type-1 domain | 0 | DIRECT |
Domain of poly(ADP-ribose) polymerase | 0 | DIRECT |
ThrRS/AlaRS common domain | 0 | DIRECT |
DNA repair protein MutS, domain III | 0 | DIRECT |
MFPT repeat-like | 0 | DIRECT |
Troponin coil-coiled subunits | 0 | DIRECT |
Pepsin inhibitor-3 | 0 | DIRECT |
PK beta-barrel domain-like | 0 | DIRECT |
ValRS/IleRS/LeuRS editing domain | 0 | DIRECT |
Cystatin/monellin | 0 | DIRECT |
Molybdenum cofactor-binding domain | 0 | DIRECT |
R3H domain | 0 | DIRECT |
eIF4e-like | 0 | DIRECT |
S-adenosylmethionine synthetase | 0 | DIRECT |
Ribosomal protein L10-like | 0 | DIRECT |
Ribosomal proteins S24e, L23 and L15e | 0 | DIRECT |
Doublecortin (DC) | 0 | DIRECT |
Rap/Ran-GAP | 0 | DIRECT |
CBD9-like | 0 | DIRECT |
GYF domain | 0 | DIRECT |
Transducin (heterotrimeric G protein), gamma chain | 0 | DIRECT |
Diaminopimelate epimerase-like | 0 | DIRECT |
Transducin (alpha subunit), insertion domain | 0 | DIRECT |
Nucleoporin domain | 0 | DIRECT |
Terpenoid cyclases/Protein prenyltransferases | 0 | DIRECT |
PEP carboxykinase-like | 0 | DIRECT |
Hypothetical protein c14orf129, hspc210 | 0 | DIRECT |
Isocitrate/Isopropylmalate dehydrogenase-like | 0 | DIRECT |
Mitochondrial carrier | 0 | DIRECT |
Rudiment single hybrid motif | 0 | DIRECT |
YWTD domain | 0 | DIRECT |
RBP11-like subunits of RNA polymerase | 0 | DIRECT |
YbiA-like | 0 | DIRECT |
Citrate synthase | 0 | DIRECT |
CO dehydrogenase molybdoprotein N-domain-like | 0 | DIRECT |
PurM C-terminal domain-like | 0 | DIRECT |
SPOC domain-like | 0 | DIRECT |
Blood coagulation inhibitor (disintegrin) | 0 | DIRECT |
CRAL/TRIO N-terminal domain | 0 | DIRECT |
L-aspartase-like | 0 | DIRECT |
ARID-like | 0 | DIRECT |
Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
VPS9 domain | 0 | DIRECT |
LEM domain | 0 | DIRECT |
Proton glutamate symport protein | 0 | DIRECT |
Class II aaRS ABD-related | 0 | DIRECT |
Complement control module/SCR domain | 0 | DIRECT |
Fibrinogen C-terminal domain-like | 0 | DIRECT |
Cation efflux protein cytoplasmic domain-like | 0 | DIRECT |
FAD-binding/transporter-associated domain-like | 0 | DIRECT |
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0 | DIRECT |
Thiamin diphosphate-binding fold (THDP-binding) | 0 | DIRECT |
Small-conductance potassium channel | 0 | DIRECT |
Creatinase/prolidase N-terminal domain | 0 | DIRECT |
Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | DIRECT |
HRDC-like | 0 | DIRECT |
GAS2 domain-like | 0 | DIRECT |
Acid phosphatase/Vanadium-dependent haloperoxidase | 0 | DIRECT |
Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | DIRECT |
PEBP-like | 0 | DIRECT |
Outer arm dynein light chain 1 | 0 | DIRECT |
Bacterial exopeptidase dimerisation domain | 0 | DIRECT |
Aminoacid dehydrogenase-like, N-terminal domain | 0 | DIRECT |
Elafin-like | 0 | DIRECT |
WGR domain-like | 0 | DIRECT |
alpha/beta knot | 0 | DIRECT |
Pentein | 0 | DIRECT |
CO dehydrogenase ISP C-domain like | 0 | DIRECT |
Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
TGS-like | 0 | DIRECT |
Annexin | 0 | DIRECT |
Carbohydrate phosphatase | 0 | DIRECT |
Translational machinery components | 0 | DIRECT |
Sec63 N-terminal domain-like | 0 | DIRECT |
Glycolipid transfer protein, GLTP | 0 | DIRECT |
Cytochrome c | 0 | DIRECT |
Heme-dependent catalase-like | 0 | DIRECT |
FAD-linked oxidases, C-terminal domain | 0 | DIRECT |
PapD-like | 0.0003348 | DIRECT |
Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
Radical SAM enzymes | 0 | Direct |
Cadherin-like | 0 | Direct |
5' to 3' exonuclease, C-terminal subdomain | 0 | Direct |
AN1-like Zinc finger | 0 | Direct |
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | Direct |
Hormone receptor domain | 0 | Direct |
PEP carboxykinase N-terminal domain | 0 | Direct |
FF domain | 0 | Direct |
C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
Nucleoside diphosphate kinase, NDK | 0 | Direct |
Zn-binding ribosomal proteins | 0 | Direct |
Tricorn protease domain 2 | 0 | Direct |
Phosphoenolpyruvate/pyruvate domain | 0 | Direct |
Ribokinase-like | 0 | Direct |
Surp module (SWAP domain) | 0 | Direct |
Cdc48 domain 2-like | 0 | Direct |
Ribulose-phoshate binding barrel | 0 | Direct |
ArfGap/RecO-like zinc finger | 0 | Direct |
MIR domain | 0 | Direct |
Hedgehog/intein (Hint) domain | 0 | Direct |
TK C-terminal domain-like | 0 | Direct |
ADP-ribosylation | 0 | Direct |
LDH C-terminal domain-like | 0 | Direct |
Single hybrid motif | 0 | Direct |
Galactose oxidase, central domain | 0 | Direct |
Ribosomal protein L1 | 0 | Direct |
PGBD-like | 0 | Direct |
MgtE membrane domain-like | 0 | Direct |
Ribosomal protein S10 | 0 | Direct |
Ferritin-like | 0 | Direct |
Tubby C-terminal domain-like | 0 | Direct |
Restriction endonuclease-like | 0 | Direct |
SWIB/MDM2 domain | 0 | Direct |
Cu,Zn superoxide dismutase-like | 0 | Direct |
Chitinase insertion domain | 0 | Direct |
Oxysterol-binding protein-like | 0 | Direct |
N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
MOSC N-terminal domain-like | 0 | Direct |
PHM/PNGase F | 0 | Direct |
PABC (PABP) domain | 0 | Direct |
Phoshotransferase/anion transport protein | 0 | Direct |
SAND domain-like | 0 | Direct |
Ran binding protein zinc finger-like | 0 | Direct |
FtsH protease domain-like | 0 | Direct |
ALDH-like | 0 | Direct |
PurM N-terminal domain-like | 0 | Direct |
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | Direct |
HSP90 C-terminal domain | 0 | Direct |
LysM domain | 0 | Direct |
PreATP-grasp domain | 0 | Direct |
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
Thyroglobulin type-1 domain | 0 | Direct |
Domain of poly(ADP-ribose) polymerase | 0 | Direct |
ThrRS/AlaRS common domain | 0 | Direct |
DNA repair protein MutS, domain III | 0 | Direct |
MFPT repeat-like | 0 | Direct |
Troponin coil-coiled subunits | 0 | Direct |
Pepsin inhibitor-3 | 0 | Direct |
PK beta-barrel domain-like | 0 | Direct |
ValRS/IleRS/LeuRS editing domain | 0 | Direct |
Cystatin/monellin | 0 | Direct |
Molybdenum cofactor-binding domain | 0 | Direct |
R3H domain | 0 | Direct |
eIF4e-like | 0 | Direct |
S-adenosylmethionine synthetase | 0 | Direct |
Ribosomal protein L10-like | 0 | Direct |
Ribosomal proteins S24e, L23 and L15e | 0 | Direct |
Doublecortin (DC) | 0 | Direct |
Rap/Ran-GAP | 0 | Direct |
CBD9-like | 0 | Direct |
GYF domain | 0 | Direct |
Transducin (heterotrimeric G protein), gamma chain | 0 | Direct |
Diaminopimelate epimerase-like | 0 | Direct |
Transducin (alpha subunit), insertion domain | 0 | Direct |
Nucleoporin domain | 0 | Direct |
Terpenoid cyclases/Protein prenyltransferases | 0 | Direct |
PEP carboxykinase-like | 0 | Direct |
Hypothetical protein c14orf129, hspc210 | 0 | Direct |
Isocitrate/Isopropylmalate dehydrogenase-like | 0 | Direct |
Mitochondrial carrier | 0 | Direct |
Rudiment single hybrid motif | 0 | Direct |
YWTD domain | 0 | Direct |
RBP11-like subunits of RNA polymerase | 0 | Direct |
YbiA-like | 0 | Direct |
Citrate synthase | 0 | Direct |
CO dehydrogenase molybdoprotein N-domain-like | 0 | Direct |
PurM C-terminal domain-like | 0 | Direct |
SPOC domain-like | 0 | Direct |
Blood coagulation inhibitor (disintegrin) | 0 | Direct |
CRAL/TRIO N-terminal domain | 0 | Direct |
L-aspartase-like | 0 | Direct |
ARID-like | 0 | Direct |
Composite domain of metallo-dependent hydrolases | 0 | Direct |
VPS9 domain | 0 | Direct |
LEM domain | 0 | Direct |
Proton glutamate symport protein | 0 | Direct |
Class II aaRS ABD-related | 0 | Direct |
Complement control module/SCR domain | 0 | Direct |
Fibrinogen C-terminal domain-like | 0 | Direct |
Cation efflux protein cytoplasmic domain-like | 0 | Direct |
FAD-binding/transporter-associated domain-like | 0 | Direct |
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0 | Direct |
Thiamin diphosphate-binding fold (THDP-binding) | 0 | Direct |
Small-conductance potassium channel | 0 | Direct |
Creatinase/prolidase N-terminal domain | 0 | Direct |
Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | Direct |
HRDC-like | 0 | Direct |
GAS2 domain-like | 0 | Direct |
Acid phosphatase/Vanadium-dependent haloperoxidase | 0 | Direct |
Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | Direct |
PEBP-like | 0 | Direct |
Outer arm dynein light chain 1 | 0 | Direct |
Bacterial exopeptidase dimerisation domain | 0 | Direct |
Aminoacid dehydrogenase-like, N-terminal domain | 0 | Direct |
Elafin-like | 0 | Direct |
WGR domain-like | 0 | Direct |
alpha/beta knot | 0 | Direct |
Pentein | 0 | Direct |
CO dehydrogenase ISP C-domain like | 0 | Direct |
Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
TGS-like | 0 | Direct |
Annexin | 0 | Direct |
Carbohydrate phosphatase | 0 | Direct |
Translational machinery components | 0 | Direct |
Sec63 N-terminal domain-like | 0 | Direct |
Glycolipid transfer protein, GLTP | 0 | Direct |
Cytochrome c | 0 | Direct |
Heme-dependent catalase-like | 0 | Direct |
FAD-linked oxidases, C-terminal domain | 0 | Direct |
PapD-like | 0.0003348 | Direct |
(show details)
Supra-domains annotated to this WP term (Not in SPWP)
Highlighted in gray are those with FDR>0.001
Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
81324,81296 81324 - Voltage-gated potassium channels 81296 - E set domains | 0 | DIRECT |
48179,48179 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | DIRECT |
56176,55103 56176 - FAD-binding/transporter-associated domain-like 55103 - FAD-linked oxidases, C-terminal domain | 0 | DIRECT |
51905,56425 51905 - FAD/NAD(P)-binding domain 56425 - Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | DIRECT |
161093,161093 161093 - MgtE membrane domain-like 161093 - MgtE membrane domain-like | 0 | DIRECT |
52540,90123 52540 - P-loop containing nucleoside triphosphate hydrolases 90123 - ABC transporter transmembrane region | 0 | DIRECT |
48334,52540 48334 - DNA repair protein MutS, domain III 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
141739,141739 141739 - MFPT repeat-like 141739 - MFPT repeat-like | 0 | DIRECT |
54495,46934 54495 - UBC-like 46934 - UBA-like | 0 | DIRECT |
57196,63825 57196 - EGF/Laminin 63825 - YWTD domain | 0 | DIRECT |
51735,56327 51735 - NAD(P)-binding Rossmann-fold domains 56327 - LDH C-terminal domain-like | 0 | DIRECT |
64356,49447 64356 - SNARE-like 49447 - Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
46938,52087 46938 - CRAL/TRIO N-terminal domain 52087 - CRAL/TRIO domain | 0 | DIRECT |
56112,48371 56112 - Protein kinase-like (PK-like) 48371 - ARM repeat | 0 | DIRECT |
52540,81271 52540 - P-loop containing nucleoside triphosphate hydrolases 81271 - TGS-like | 0 | DIRECT |
50729,47473 50729 - PH domain-like 47473 - EF-hand | 0 | DIRECT |
57903,82199 57903 - FYVE/PHD zinc finger 82199 - SET domain | 0 | DIRECT |
47473,51695 47473 - EF-hand 51695 - PLC-like phosphodiesterases | 0 | DIRECT |
47741,56176 47741 - CO dehydrogenase ISP C-domain like 56176 - FAD-binding/transporter-associated domain-like | 0 | DIRECT |
55486,57552 55486 - Metalloproteases ("zincins"), catalytic domain 57552 - Blood coagulation inhibitor (disintegrin) | 0 | DIRECT |
49742,49742 49742 - PHM/PNGase F 49742 - PHM/PNGase F | 0 | DIRECT |
52518,52922 52518 - Thiamin diphosphate-binding fold (THDP-binding) 52922 - TK C-terminal domain-like | 0 | DIRECT |
47576,47576 47576 - Calponin-homology domain, CH-domain 47576 - Calponin-homology domain, CH-domain | 0 | DIRECT |
55973,55973 55973 - S-adenosylmethionine synthetase 55973 - S-adenosylmethionine synthetase | 0 | DIRECT |
57362,57362 57362 - BPTI-like 57362 - BPTI-like | 0 | DIRECT |
68923,53795 68923 - PEP carboxykinase N-terminal domain 53795 - PEP carboxykinase-like | 0 | DIRECT |
52440,56059 52440 - PreATP-grasp domain 56059 - Glutathione synthetase ATP-binding domain-like | 0 | DIRECT |
50677,52374 50677 - ValRS/IleRS/LeuRS editing domain 52374 - Nucleotidylyl transferase | 0 | DIRECT |
57196,49899 57196 - EGF/Laminin 49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
52540,46785 52540 - P-loop containing nucleoside triphosphate hydrolases 46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
50692,54585 50692 - ADC-like 54585 - Cdc48 domain 2-like | 0 | DIRECT |
54001,49758 54001 - Cysteine proteinases 49758 - Calpain large subunit, middle domain (domain III) | 0 | DIRECT |
57535,57535 57535 - Complement control module/SCR domain 57535 - Complement control module/SCR domain | 0 | DIRECT |
57863,48403 57863 - ArfGap/RecO-like zinc finger 48403 - Ankyrin repeat | 0 | DIRECT |
51971,54373 51971 - Nucleotide-binding domain 54373 - FAD-linked reductases, C-terminal domain | 0 | DIRECT |
47769,47769 47769 - SAM/Pointed domain 47769 - SAM/Pointed domain | 0 | DIRECT |
81383,52047 81383 - F-box domain 52047 - RNI-like | 0 | DIRECT |
81698,81698 81698 - FF domain 81698 - FF domain | 0 | DIRECT |
51338,51556 51338 - Composite domain of metallo-dependent hydrolases 51556 - Metallo-dependent hydrolases | 0 | DIRECT |
55729,55729 55729 - Acyl-CoA N-acyltransferases (Nat) 55729 - Acyl-CoA N-acyltransferases (Nat) | 0 | DIRECT |
55486,50923 55486 - Metalloproteases ("zincins"), catalytic domain 50923 - Hemopexin-like domain | 0 | DIRECT |
51445,54556 51445 - (Trans)glycosidases 54556 - Chitinase insertion domain | 0 | DIRECT |
47895,52540 47895 - Transducin (alpha subunit), insertion domain 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
52540,47917 52540 - P-loop containing nucleoside triphosphate hydrolases 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
54160,52540 54160 - Chromo domain-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
48425,50729 48425 - Sec7 domain 50729 - PH domain-like | 0 | DIRECT |
49313,49313 49313 - Cadherin-like 49313 - Cadherin-like | 0 | DIRECT |
46785,46785 46785 - "Winged helix" DNA-binding domain 46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
55326,56042 55326 - PurM N-terminal domain-like 56042 - PurM C-terminal domain-like | 0 | DIRECT |
49562,48371 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) 48371 - ARM repeat | 0 | DIRECT |
47203,47203 47203 - Acyl-CoA dehydrogenase C-terminal domain-like 47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
51735,55347 51735 - NAD(P)-binding Rossmann-fold domains 55347 - Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | DIRECT |
81383,50978 81383 - F-box domain 50978 - WD40 repeat-like | 0 | DIRECT |
52518,52518 52518 - Thiamin diphosphate-binding fold (THDP-binding) 52518 - Thiamin diphosphate-binding fold (THDP-binding) | 0 | DIRECT |
54897,53187 54897 - Protease propeptides/inhibitors 53187 - Zn-dependent exopeptidases | 0 | DIRECT |
47587,56399 47587 - Domain of poly(ADP-ribose) polymerase 56399 - ADP-ribosylation | 0 | DIRECT |
54534,54534 54534 - FKBP-like 54534 - FKBP-like | 0 | DIRECT |
144232,82199 144232 - HIT/MYND zinc finger-like 82199 - SET domain | 0 | DIRECT |
54160,54160 54160 - Chromo domain-like 54160 - Chromo domain-like | 0 | DIRECT |
48403,52151 48403 - Ankyrin repeat 52151 - FabD/lysophospholipase-like | 0 | DIRECT |
81324,53850 81324 - Voltage-gated potassium channels 53850 - Periplasmic binding protein-like II | 0 | DIRECT |
53187,55031 53187 - Zn-dependent exopeptidases 55031 - Bacterial exopeptidase dimerisation domain | 0 | DIRECT |
47473,103506 47473 - EF-hand 103506 - Mitochondrial carrier | 0 | DIRECT |
56601,48403 56601 - beta-lactamase/transpeptidase-like 48403 - Ankyrin repeat | 0 | DIRECT |
54665,56003 54665 - CO dehydrogenase molybdoprotein N-domain-like 56003 - Molybdenum cofactor-binding domain | 0 | DIRECT |
161111,160240 161111 - Cation efflux protein transmembrane domain-like 160240 - Cation efflux protein cytoplasmic domain-like | 0 | DIRECT |
141673,50800 141673 - MOSC N-terminal domain-like 50800 - PK beta-barrel domain-like | 0 | DIRECT |
55681,52954 55681 - Class II aaRS and biotin synthetases 52954 - Class II aaRS ABD-related | 0 | DIRECT |
52540,140990 52540 - P-loop containing nucleoside triphosphate hydrolases 140990 - FtsH protease domain-like | 0 | DIRECT |
54292,47741 54292 - 2Fe-2S ferredoxin-like 47741 - CO dehydrogenase ISP C-domain like | 0 | DIRECT |
51556,51338 51556 - Metallo-dependent hydrolases 51338 - Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
47090,55486 47090 - PGBD-like 55486 - Metalloproteases ("zincins"), catalytic domain | 0 | DIRECT |
57903,51197 57903 - FYVE/PHD zinc finger 51197 - Clavaminate synthase-like | 0 | DIRECT |
54585,52540 54585 - Cdc48 domain 2-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
55920,46785 55920 - Creatinase/aminopeptidase 46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
81324,81327 81324 - Voltage-gated potassium channels 81327 - Small-conductance potassium channel | 0 | DIRECT |
50978,50998 50978 - WD40 repeat-like 50998 - Quinoprotein alcohol dehydrogenase-like | 0 | DIRECT |
57850,117839 57850 - RING/U-box 117839 - WWE domain | 0 | DIRECT |
56672,100879 56672 - DNA/RNA polymerases 100879 - Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
55394,55394 55394 - Bactericidal permeability-increasing protein, BPI 55394 - Bactericidal permeability-increasing protein, BPI | 0 | DIRECT |
56059,51246 56059 - Glutathione synthetase ATP-binding domain-like 51246 - Rudiment single hybrid motif | 0 | DIRECT |
Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
81324,81296 81324 - Voltage-gated potassium channels 81296 - E set domains | 0 | Direct |
48179,48179 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | Direct |
56176,55103 56176 - FAD-binding/transporter-associated domain-like 55103 - FAD-linked oxidases, C-terminal domain | 0 | Direct |
51905,56425 51905 - FAD/NAD(P)-binding domain 56425 - Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | Direct |
161093,161093 161093 - MgtE membrane domain-like 161093 - MgtE membrane domain-like | 0 | Direct |
52540,90123 52540 - P-loop containing nucleoside triphosphate hydrolases 90123 - ABC transporter transmembrane region | 0 | Direct |
48334,52540 48334 - DNA repair protein MutS, domain III 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
141739,141739 141739 - MFPT repeat-like 141739 - MFPT repeat-like | 0 | Direct |
54495,46934 54495 - UBC-like 46934 - UBA-like | 0 | Direct |
57196,63825 57196 - EGF/Laminin 63825 - YWTD domain | 0 | Direct |
51735,56327 51735 - NAD(P)-binding Rossmann-fold domains 56327 - LDH C-terminal domain-like | 0 | Direct |
64356,49447 64356 - SNARE-like 49447 - Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
46938,52087 46938 - CRAL/TRIO N-terminal domain 52087 - CRAL/TRIO domain | 0 | Direct |
56112,48371 56112 - Protein kinase-like (PK-like) 48371 - ARM repeat | 0 | Direct |
52540,81271 52540 - P-loop containing nucleoside triphosphate hydrolases 81271 - TGS-like | 0 | Direct |
50729,47473 50729 - PH domain-like 47473 - EF-hand | 0 | Direct |
57903,82199 57903 - FYVE/PHD zinc finger 82199 - SET domain | 0 | Direct |
47473,51695 47473 - EF-hand 51695 - PLC-like phosphodiesterases | 0 | Direct |
47741,56176 47741 - CO dehydrogenase ISP C-domain like 56176 - FAD-binding/transporter-associated domain-like | 0 | Direct |
55486,57552 55486 - Metalloproteases ("zincins"), catalytic domain 57552 - Blood coagulation inhibitor (disintegrin) | 0 | Direct |
49742,49742 49742 - PHM/PNGase F 49742 - PHM/PNGase F | 0 | Direct |
52518,52922 52518 - Thiamin diphosphate-binding fold (THDP-binding) 52922 - TK C-terminal domain-like | 0 | Direct |
47576,47576 47576 - Calponin-homology domain, CH-domain 47576 - Calponin-homology domain, CH-domain | 0 | Direct |
55973,55973 55973 - S-adenosylmethionine synthetase 55973 - S-adenosylmethionine synthetase | 0 | Direct |
57362,57362 57362 - BPTI-like 57362 - BPTI-like | 0 | Direct |
68923,53795 68923 - PEP carboxykinase N-terminal domain 53795 - PEP carboxykinase-like | 0 | Direct |
52440,56059 52440 - PreATP-grasp domain 56059 - Glutathione synthetase ATP-binding domain-like | 0 | Direct |
50677,52374 50677 - ValRS/IleRS/LeuRS editing domain 52374 - Nucleotidylyl transferase | 0 | Direct |
57196,49899 57196 - EGF/Laminin 49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
52540,46785 52540 - P-loop containing nucleoside triphosphate hydrolases 46785 - "Winged helix" DNA-binding domain | 0 | Direct |
50692,54585 50692 - ADC-like 54585 - Cdc48 domain 2-like | 0 | Direct |
54001,49758 54001 - Cysteine proteinases 49758 - Calpain large subunit, middle domain (domain III) | 0 | Direct |
57535,57535 57535 - Complement control module/SCR domain 57535 - Complement control module/SCR domain | 0 | Direct |
57863,48403 57863 - ArfGap/RecO-like zinc finger 48403 - Ankyrin repeat | 0 | Direct |
51971,54373 51971 - Nucleotide-binding domain 54373 - FAD-linked reductases, C-terminal domain | 0 | Direct |
47769,47769 47769 - SAM/Pointed domain 47769 - SAM/Pointed domain | 0 | Direct |
81383,52047 81383 - F-box domain 52047 - RNI-like | 0 | Direct |
81698,81698 81698 - FF domain 81698 - FF domain | 0 | Direct |
51338,51556 51338 - Composite domain of metallo-dependent hydrolases 51556 - Metallo-dependent hydrolases | 0 | Direct |
55729,55729 55729 - Acyl-CoA N-acyltransferases (Nat) 55729 - Acyl-CoA N-acyltransferases (Nat) | 0 | Direct |
55486,50923 55486 - Metalloproteases ("zincins"), catalytic domain 50923 - Hemopexin-like domain | 0 | Direct |
51445,54556 51445 - (Trans)glycosidases 54556 - Chitinase insertion domain | 0 | Direct |
47895,52540 47895 - Transducin (alpha subunit), insertion domain 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
52540,47917 52540 - P-loop containing nucleoside triphosphate hydrolases 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
54160,52540 54160 - Chromo domain-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
48425,50729 48425 - Sec7 domain 50729 - PH domain-like | 0 | Direct |
49313,49313 49313 - Cadherin-like 49313 - Cadherin-like | 0 | Direct |
46785,46785 46785 - "Winged helix" DNA-binding domain 46785 - "Winged helix" DNA-binding domain | 0 | Direct |
55326,56042 55326 - PurM N-terminal domain-like 56042 - PurM C-terminal domain-like | 0 | Direct |
49562,48371 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) 48371 - ARM repeat | 0 | Direct |
47203,47203 47203 - Acyl-CoA dehydrogenase C-terminal domain-like 47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
51735,55347 51735 - NAD(P)-binding Rossmann-fold domains 55347 - Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | Direct |
81383,50978 81383 - F-box domain 50978 - WD40 repeat-like | 0 | Direct |
52518,52518 52518 - Thiamin diphosphate-binding fold (THDP-binding) 52518 - Thiamin diphosphate-binding fold (THDP-binding) | 0 | Direct |
54897,53187 54897 - Protease propeptides/inhibitors 53187 - Zn-dependent exopeptidases | 0 | Direct |
47587,56399 47587 - Domain of poly(ADP-ribose) polymerase 56399 - ADP-ribosylation | 0 | Direct |
54534,54534 54534 - FKBP-like 54534 - FKBP-like | 0 | Direct |
144232,82199 144232 - HIT/MYND zinc finger-like 82199 - SET domain | 0 | Direct |
54160,54160 54160 - Chromo domain-like 54160 - Chromo domain-like | 0 | Direct |
48403,52151 48403 - Ankyrin repeat 52151 - FabD/lysophospholipase-like | 0 | Direct |
81324,53850 81324 - Voltage-gated potassium channels 53850 - Periplasmic binding protein-like II | 0 | Direct |
53187,55031 53187 - Zn-dependent exopeptidases 55031 - Bacterial exopeptidase dimerisation domain | 0 | Direct |
47473,103506 47473 - EF-hand 103506 - Mitochondrial carrier | 0 | Direct |
56601,48403 56601 - beta-lactamase/transpeptidase-like 48403 - Ankyrin repeat | 0 | Direct |
54665,56003 54665 - CO dehydrogenase molybdoprotein N-domain-like 56003 - Molybdenum cofactor-binding domain | 0 | Direct |
161111,160240 161111 - Cation efflux protein transmembrane domain-like 160240 - Cation efflux protein cytoplasmic domain-like | 0 | Direct |
141673,50800 141673 - MOSC N-terminal domain-like 50800 - PK beta-barrel domain-like | 0 | Direct |
55681,52954 55681 - Class II aaRS and biotin synthetases 52954 - Class II aaRS ABD-related | 0 | Direct |
52540,140990 52540 - P-loop containing nucleoside triphosphate hydrolases 140990 - FtsH protease domain-like | 0 | Direct |
54292,47741 54292 - 2Fe-2S ferredoxin-like 47741 - CO dehydrogenase ISP C-domain like | 0 | Direct |
51556,51338 51556 - Metallo-dependent hydrolases 51338 - Composite domain of metallo-dependent hydrolases | 0 | Direct |
47090,55486 47090 - PGBD-like 55486 - Metalloproteases ("zincins"), catalytic domain | 0 | Direct |
57903,51197 57903 - FYVE/PHD zinc finger 51197 - Clavaminate synthase-like | 0 | Direct |
54585,52540 54585 - Cdc48 domain 2-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
55920,46785 55920 - Creatinase/aminopeptidase 46785 - "Winged helix" DNA-binding domain | 0 | Direct |
81324,81327 81324 - Voltage-gated potassium channels 81327 - Small-conductance potassium channel | 0 | Direct |
50978,50998 50978 - WD40 repeat-like 50998 - Quinoprotein alcohol dehydrogenase-like | 0 | Direct |
57850,117839 57850 - RING/U-box 117839 - WWE domain | 0 | Direct |
56672,100879 56672 - DNA/RNA polymerases 100879 - Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
55394,55394 55394 - Bactericidal permeability-increasing protein, BPI 55394 - Bactericidal permeability-increasing protein, BPI | 0 | Direct |
56059,51246 56059 - Glutathione synthetase ATP-binding domain-like 51246 - Rudiment single hybrid motif | 0 | Direct |
(show details)
Supra-domains annotated to this WP term (Not in SPWP)
Highlighted in gray are those with FDR>0.001
Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
56645,47203,47203 56645 - Acyl-CoA dehydrogenase NM domain-like 47203 - Acyl-CoA dehydrogenase C-terminal domain-like 47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
46938,52087,101576 46938 - CRAL/TRIO N-terminal domain 52087 - CRAL/TRIO domain 101576 - Supernatant protein factor (SPF), C-terminal domain | 0 | DIRECT |
54292,47741,56176 54292 - 2Fe-2S ferredoxin-like 47741 - CO dehydrogenase ISP C-domain like 56176 - FAD-binding/transporter-associated domain-like | 0 | DIRECT |
50729,47473,51695 50729 - PH domain-like 47473 - EF-hand 51695 - PLC-like phosphodiesterases | 0 | DIRECT |
90123,52540,90123 90123 - ABC transporter transmembrane region 52540 - P-loop containing nucleoside triphosphate hydrolases 90123 - ABC transporter transmembrane region | 0 | DIRECT |
56436,49854,49854 56436 - C-type lectin-like 49854 - Spermadhesin, CUB domain 49854 - Spermadhesin, CUB domain | 0 | DIRECT |
47090,55486,50923 47090 - PGBD-like 55486 - Metalloproteases ("zincins"), catalytic domain 50923 - Hemopexin-like domain | 0 | DIRECT |
49313,49313,49313 49313 - Cadherin-like 49313 - Cadherin-like 49313 - Cadherin-like | 0 | DIRECT |
55973,55973,55973 55973 - S-adenosylmethionine synthetase 55973 - S-adenosylmethionine synthetase 55973 - S-adenosylmethionine synthetase | 0 | DIRECT |
54160,52540,52540 54160 - Chromo domain-like 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
50692,54585,52540 50692 - ADC-like 54585 - Cdc48 domain 2-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
57362,57362,57362 57362 - BPTI-like 57362 - BPTI-like 57362 - BPTI-like | 0 | DIRECT |
52540,90123,52540 52540 - P-loop containing nucleoside triphosphate hydrolases 90123 - ABC transporter transmembrane region 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
52440,56059,51246 52440 - PreATP-grasp domain 56059 - Glutathione synthetase ATP-binding domain-like 51246 - Rudiment single hybrid motif | 0 | DIRECT |
57535,57535,57535 57535 - Complement control module/SCR domain 57535 - Complement control module/SCR domain 57535 - Complement control module/SCR domain | 0 | DIRECT |
50044,50044,50044 50044 - SH3-domain 50044 - SH3-domain 50044 - SH3-domain | 0 | DIRECT |
57567,57567,57567 57567 - Serine protease inhibitors 57567 - Serine protease inhibitors 57567 - Serine protease inhibitors | 0 | DIRECT |
54585,52540,52540 54585 - Cdc48 domain 2-like 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
51735,48179,48179 51735 - NAD(P)-binding Rossmann-fold domains 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | DIRECT |
52540,52540,52540 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
54160,54160,52540 54160 - Chromo domain-like 54160 - Chromo domain-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
48726,49265,48726 48726 - Immunoglobulin 49265 - Fibronectin type III 48726 - Immunoglobulin | 0 | DIRECT |
49562,48371,56112 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) 48371 - ARM repeat 56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
56645,47203,47203 56645 - Acyl-CoA dehydrogenase NM domain-like 47203 - Acyl-CoA dehydrogenase C-terminal domain-like 47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
46938,52087,101576 46938 - CRAL/TRIO N-terminal domain 52087 - CRAL/TRIO domain 101576 - Supernatant protein factor (SPF), C-terminal domain | 0 | Direct |
54292,47741,56176 54292 - 2Fe-2S ferredoxin-like 47741 - CO dehydrogenase ISP C-domain like 56176 - FAD-binding/transporter-associated domain-like | 0 | Direct |
50729,47473,51695 50729 - PH domain-like 47473 - EF-hand 51695 - PLC-like phosphodiesterases | 0 | Direct |
90123,52540,90123 90123 - ABC transporter transmembrane region 52540 - P-loop containing nucleoside triphosphate hydrolases 90123 - ABC transporter transmembrane region | 0 | Direct |
56436,49854,49854 56436 - C-type lectin-like 49854 - Spermadhesin, CUB domain 49854 - Spermadhesin, CUB domain | 0 | Direct |
47090,55486,50923 47090 - PGBD-like 55486 - Metalloproteases ("zincins"), catalytic domain 50923 - Hemopexin-like domain | 0 | Direct |
49313,49313,49313 49313 - Cadherin-like 49313 - Cadherin-like 49313 - Cadherin-like | 0 | Direct |
55973,55973,55973 55973 - S-adenosylmethionine synthetase 55973 - S-adenosylmethionine synthetase 55973 - S-adenosylmethionine synthetase | 0 | Direct |
54160,52540,52540 54160 - Chromo domain-like 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
50692,54585,52540 50692 - ADC-like 54585 - Cdc48 domain 2-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
57362,57362,57362 57362 - BPTI-like 57362 - BPTI-like 57362 - BPTI-like | 0 | Direct |
52540,90123,52540 52540 - P-loop containing nucleoside triphosphate hydrolases 90123 - ABC transporter transmembrane region 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
52440,56059,51246 52440 - PreATP-grasp domain 56059 - Glutathione synthetase ATP-binding domain-like 51246 - Rudiment single hybrid motif | 0 | Direct |
57535,57535,57535 57535 - Complement control module/SCR domain 57535 - Complement control module/SCR domain 57535 - Complement control module/SCR domain | 0 | Direct |
50044,50044,50044 50044 - SH3-domain 50044 - SH3-domain 50044 - SH3-domain | 0 | Direct |
57567,57567,57567 57567 - Serine protease inhibitors 57567 - Serine protease inhibitors 57567 - Serine protease inhibitors | 0 | Direct |
54585,52540,52540 54585 - Cdc48 domain 2-like 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
51735,48179,48179 51735 - NAD(P)-binding Rossmann-fold domains 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | Direct |
52540,52540,52540 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
54160,54160,52540 54160 - Chromo domain-like 54160 - Chromo domain-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
48726,49265,48726 48726 - Immunoglobulin 49265 - Fibronectin type III 48726 - Immunoglobulin | 0 | Direct |
49562,48371,56112 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) 48371 - ARM repeat 56112 - Protein kinase-like (PK-like) | 0 | Direct |
Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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Trees by TreeVector
A presence/absence matrix is generated using protein domains and supradomains
for all genomes in SUPERFAMILY. The RAxML
software is used to produce a single, large tree topology using
heuristic parsimony methods. Genome combinations, or specific clades, can be displayed as
if individual trees had been produced. However, this data is extracted from the single
large tree. This produces a higher quality topology than if the trees had been produced
on their own, and allows the trees to be displayed instantly.
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