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Worm Phenotype (WP): organism stress response variant

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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)

Shortest distance to current term (+ for parents, - for children) WP term [WP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + 5:   Variant [WBPhenotype:0000886] <2>
+ + + + 4:   physiology variant [WBPhenotype:0000519] <14>(510|587) (510|248|69)
+ + + 3:   organism physiology variant [WBPhenotype:0000576] <9>(369|431) (372|193|57)
+ + 2:   organism homeostasis metabolism variant [WBPhenotype:0000577] <16>(361|421) (363|190|56)
+ 1:   organism environmental stimulus response variant [WBPhenotype:0000738] <15>(137|128) (138|57|18)
0:   organism stress response variant [WBPhenotype:0000067] <20>(75|63) (76|26|7)
- 1:   cell stress response variant [WBPhenotype:0000142] <12>(20|17) (20|7|3)
- 1:   organism pathogen response variant [WBPhenotype:0001012] <10>(22|20) (23|10|3)
- 1:   organism temperature response variant [WBPhenotype:0000146] <10>(17|15) (17|6|1)
- 1:   organism osmotic stress response variant [WBPhenotype:0000876] <6>(10|8) (10|3|1)
- 1:   organism oxidative stress response variant [WBPhenotype:0001620] <6>(7|7) (7|2|0)
- 1:   organism starvation response variant [WBPhenotype:0000147] <5>(3|2) (3|1|0)
- 1:   organism ionizing radiation response variant [WBPhenotype:0000686] <4>(10|5) (10|0|0)
- 1:   anoxia response variant [WBPhenotype:0002424] <3>(1|1) (1|0|0)
- 1:   hypoxia response variant [WBPhenotype:0002423] <3>(10|6) (10|3|0)
- 1:   organism UV response variant [WBPhenotype:0000143] <3>(7|6) (7|4|2)
- 1:   methyl methanesulfonate response variant [WBPhenotype:0000498] <1>(0|0) (0|0|0)
- 1:   organism crowding response variant [WBPhenotype:0000191] <1>(0|0) (0|0|0)
- 1:   organism desiccation response variant [WBPhenotype:0001417] <1>(0|0) (0|0|0)
- 1:   rhythmic tolerance to stress variant [WBPhenotype:0001709] <1>(0|0) (0|0|0)
- 1:   stress induced lethality variant [WBPhenotype:0000139] <1>(2|2) (2|0|0)
- 1:   ethyl methanesulfonate response variant [WBPhenotype:0000499](0|0) (0|0|0)
- 1:   organism electrophilic stress hypersensitive [WBPhenotype:0001634](2|2) (2|1|0)
- 1:   organism hypersensitive interstrand cross link agents [WBPhenotype:0001796](0|0) (0|0|0)
- 1:   organism response to pH variant [WBPhenotype:0001732](0|0) (0|0|0)
- 1:   stress induced arrest variant [WBPhenotype:0000140](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
RBP11-like subunits of RNA polymerase0Direct
5' to 3' exonuclease, C-terminal subdomain0Direct
Heme-dependent catalase-like0Direct
Aromatic aminoacid monoxygenases, catalytic and oligomerization domains0Direct
ValRS/IleRS/LeuRS editing domain0Direct
HRDC-like0Direct
Lipovitellin-phosvitin complex; beta-sheet shell regions0Direct
Lipovitellin-phosvitin complex, superhelical domain0Direct
Heat shock protein 70kD (HSP70), peptide-binding domain0.0000001108Direct
Heat shock protein 70kD (HSP70), C-terminal subdomain0.0000009272Direct
GST C-terminal domain-like0.00002064Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase0.00003167Direct
PIN domain-like0.00003222Direct
Thioredoxin-like0.00004032Direct
F1F0 ATP synthase subunit C0.0002039Direct
ARID-like0.0002039Direct
Aquaporin-like0.0003384Direct
Class II aaRS ABD-related0.000606Direct
Cysteine-rich domain0.0009124Direct
Di-copper centre-containing domain0.000996Direct
PLC-like phosphodiesterases0.002865Inherited
NAD kinase/diacylglycerol kinase-like0.00317Inherited
Class II aaRS and biotin synthetases0.003784Inherited
Saposin0.004475Inherited
PH domain-like0.005305Inherited
Nucleotidylyl transferase0.008945Inherited
HSP20-like chaperones0.009602Inherited
FAD/NAD-linked reductases, dimerisation (C-terminal) domain0.01262Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.02411Inherited
ACP-like0.02446Inherited
DBL homology domain (DH-domain)0.02994Inherited
GroEL apical domain-like0.03807Inherited
GroEL equatorial domain-like0.03807Inherited
GroEL-intermediate domain like0.03807Inherited
Multidrug resistance efflux transporter EmrE0.04367Inherited
Bromodomain0.05979Inherited
Hect, E3 ligase catalytic domain0.09348Inherited
RING/U-box0.1097Inherited
C2 domain (Calcium/lipid-binding domain, CaLB)0.1102Inherited
Chromo domain-like0.1122Inherited
Ankyrin repeat0.1165Inherited
Periplasmic binding protein-like II0.1352Inherited
Heme-dependent peroxidases0.1453Inherited
HD-domain/PDEase-like0.1453Inherited
Histone-fold0.1801Inherited
(Trans)glycosidases0.2103Inherited
PYP-like sensor domain (PAS domain)0.224Inherited
Arginase/deacetylase0.224Inherited
DNA/RNA polymerases0.2666Inherited
DEATH domain0.2666Inherited
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.2833Inherited
RNA-binding domain, RBD0.3051Inherited
Nucleic acid-binding proteins0.3097Inherited
FAD/NAD(P)-binding domain0.3162Inherited
Leucine zipper domain0.3586Inherited
Sm-like ribonucleoproteins0.3654Inherited
Quinoprotein alcohol dehydrogenase-like0.3654Inherited
FYVE/PHD zinc finger0.3786Inherited
PLP-dependent transferases0.4249Inherited
cAMP-binding domain-like0.4654Inherited
Lipocalins0.4654Inherited
Insulin-like0.6006Inherited
WD40 repeat-like0.7162Inherited
S-adenosyl-L-methionine-dependent methyltransferases0.744Inherited
HLH, helix-loop-helix DNA-binding domain0.8469Inherited
Metallo-dependent phosphatases0.8695Inherited
Cysteine proteinases0.9583Inherited
Protein kinase-like (PK-like)0.9722Inherited
Periplasmic binding protein-like I0.9864Inherited
P-loop containing nucleoside triphosphate hydrolases0.9922Inherited
EF-hand1Inherited
Nucleotide cyclase1Inherited
Neurotransmitter-gated ion-channel transmembrane pore1Inherited
Nicotinic receptor ligand binding domain-like1Inherited
MFS general substrate transporter1Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Lipovitellin-phosvitin complex, superhelical domain0Direct
ValRS/IleRS/LeuRS editing domain0Direct
5' to 3' exonuclease catalytic domain0Direct
5' to 3' exonuclease, C-terminal subdomain0Direct
Anticodon-binding domain of Class II aaRS0Direct
Mammalian PLC0Direct
RNA-polymerase beta0Direct
Aromatic aminoacid monoxygenases, catalytic and oligomerization domains0Direct
Lipovitellin-phosvitin complex; beta-sheet shell regions0Direct
Arginine methyltransferase0Direct
Heme-dependent catalases0Direct
PLC-like (P variant)0.0000005381Direct
Heat shock protein 70kD (HSP70), peptide-binding domain0.000001928Direct
Heat shock protein 70kD (HSP70), C-terminal subdomain0.000002781Direct
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.000002781Direct
Tandem AAA-ATPase domain0.000003028Direct
Phoshoinositide 3-kinase (PI3K), catalytic domain0.00001413Direct
Protein kinase cysteine-rich domain (cys2, phorbol-binding domain)0.00002861Direct
Aquaporin-like0.00007072Direct
Erythroid transcription factor GATA-10.0002599Direct
ARID domain0.0003357Direct
F1F0 ATP synthase subunit C0.0003357Direct
Glutathione S-transferase (GST), C-terminal domain0.0005924Direct
Glutathione S-transferase (GST), N-terminal domain0.0009017Direct
Hemocyanin middle domain0.001828Inherited
Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain0.002649Inherited
Pleckstrin-homology domain (PH domain)0.009697Inherited
Class I aminoacyl-tRNA synthetases (RS), catalytic domain0.00976Inherited
HSP200.01012Inherited
FAD/NAD-linked reductases, dimerisation (C-terminal) domain0.01801Inherited
DBL homology domain (DH-domain)0.02268Inherited
Group II chaperonin (CCT, TRIC), ATPase domain0.04799Inherited
Bromodomain0.04799Inherited
Group II chaperonin (CCT, TRIC), apical domain0.04799Inherited
RING finger domain, C3HC40.06054Inherited
Rhodopsin-like0.06826Inherited
Fatty acid binding protein-like0.07682Inherited
FAD/NAD-linked reductases, N-terminal and central domains0.07682Inherited
Armadillo repeat0.07682Inherited
Hect, E3 ligase catalytic domain0.07682Inherited
Ankyrin repeat0.09124Inherited
Phosphate binding protein-like0.1119Inherited
PDEase0.1223Inherited
Myeloperoxidase-like0.1223Inherited
Nucleosome core histones0.15Inherited
Glutathione peroxidase-like0.1597Inherited
PHD domain0.1866Inherited
Group II chaperonin (CCT, TRIC), intermediate domain0.1946Inherited
Histone deacetylase, HDAC0.1946Inherited
EF-hand modules in multidomain proteins0.1946Inherited
Chromo domain0.2508Inherited
Canonical RBD0.3101Inherited
Proteasome subunits0.3165Inherited
Leucine zipper domain0.3165Inherited
cAMP-binding domain0.4236Inherited
WD40-repeat0.4443Inherited
Insulin-like0.5559Inherited
HLH, helix-loop-helix DNA-binding domain0.8099Inherited
Protein kinases, catalytic subunit0.9343Inherited
Neurotransmitter-gated ion-channel transmembrane pore1Inherited
L-arabinose binding protein-like1Inherited
Nicotinic receptor ligand binding domain-like1Inherited
G proteins1Inherited


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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Lipovitellin-phosvitin complex, superhelical domain0Direct
Lipovitellin-phosvitin complex; beta-sheet shell regions0Direct
HRDC-like0Direct
Heme-dependent catalase-like0Direct
5' to 3' exonuclease, C-terminal subdomain0Direct
RBP11-like subunits of RNA polymerase0Direct
Aromatic aminoacid monoxygenases, catalytic and oligomerization domains0Direct
ValRS/IleRS/LeuRS editing domain0Direct
Heat shock protein 70kD (HSP70), peptide-binding domain0.0000000887Direct
Heat shock protein 70kD (HSP70), C-terminal subdomain0.0000007486Direct
GST C-terminal domain-like0.00001682Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase0.00002584Direct
PIN domain-like0.0000263Direct
Thioredoxin-like0.00003293Direct
F1F0 ATP synthase subunit C0.0001674Direct
ARID-like0.0001674Direct
Aquaporin-like0.0002788Direct
Class II aaRS ABD-related0.0005018Direct
Cysteine-rich domain0.0007588Direct
Di-copper centre-containing domain0.0008286Direct
PLC-like phosphodiesterases0.002416Inherited
NAD kinase/diacylglycerol kinase-like0.002676Inherited
Class II aaRS and biotin synthetases0.003204Inherited
Saposin0.003796Inherited
PH domain-like0.004509Inherited
Nucleotidylyl transferase0.007673Inherited
HSP20-like chaperones0.008248Inherited
FAD/NAD-linked reductases, dimerisation (C-terminal) domain0.01089Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.02105Inherited
ACP-like0.02136Inherited
DBL homology domain (DH-domain)0.02627Inherited
GroEL equatorial domain-like0.03356Inherited
GroEL apical domain-like0.03356Inherited
GroEL-intermediate domain like0.03356Inherited
Multidrug resistance efflux transporter EmrE0.03856Inherited
Bromodomain0.05323Inherited
Hect, E3 ligase catalytic domain0.08423Inherited
RING/U-box0.09926Inherited
C2 domain (Calcium/lipid-binding domain, CaLB)0.0997Inherited
Chromo domain-like0.1016Inherited
Ankyrin repeat0.1056Inherited
Periplasmic binding protein-like II0.123Inherited
Heme-dependent peroxidases0.1324Inherited
HD-domain/PDEase-like0.1324Inherited
Histone-fold0.1654Inherited
(Trans)glycosidases0.194Inherited
PYP-like sensor domain (PAS domain)0.2071Inherited
Arginase/deacetylase0.2071Inherited
DEATH domain0.2485Inherited
DNA/RNA polymerases0.2485Inherited
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.2647Inherited
RNA-binding domain, RBD0.2859Inherited
Nucleic acid-binding proteins0.2904Inherited
FAD/NAD(P)-binding domain0.2968Inherited
Leucine zipper domain0.3384Inherited
Sm-like ribonucleoproteins0.345Inherited
Quinoprotein alcohol dehydrogenase-like0.345Inherited
FYVE/PHD zinc finger0.3582Inherited
PLP-dependent transferases0.4041Inherited
Lipocalins0.4442Inherited
cAMP-binding domain-like0.4442Inherited
Insulin-like0.5788Inherited
WD40 repeat-like0.6957Inherited
S-adenosyl-L-methionine-dependent methyltransferases0.7241Inherited
HLH, helix-loop-helix DNA-binding domain0.8298Inherited
Metallo-dependent phosphatases0.8533Inherited
Cysteine proteinases0.9454Inherited
Protein kinase-like (PK-like)0.9603Inherited
Periplasmic binding protein-like I0.9757Inherited
P-loop containing nucleoside triphosphate hydrolases0.9819Inherited
Nucleotide cyclase1Inherited
Neurotransmitter-gated ion-channel transmembrane pore1Inherited
EF-hand1Inherited
Nicotinic receptor ligand binding domain-like1Inherited
MFS general substrate transporter1Inherited
Tubulin C-terminal domain-like1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
55681,52954
  • 55681 - Class II aaRS and biotin synthetases
  • 52954 - Class II aaRS ABD-related
  • 0Direct
    48431,56968
  • 48431 - Lipovitellin-phosvitin complex, superhelical domain
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 0Direct
    50729,56112
  • 50729 - PH domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    50729,47473
  • 50729 - PH domain-like
  • 47473 - EF-hand
  • 0Direct
    51695,49562
  • 51695 - PLC-like phosphodiesterases
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0Direct
    50677,52374
  • 50677 - ValRS/IleRS/LeuRS editing domain
  • 52374 - Nucleotidylyl transferase
  • 0Direct
    56968,48431
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 48431 - Lipovitellin-phosvitin complex, superhelical domain
  • 0Direct
    81333,81333
  • 81333 - F1F0 ATP synthase subunit C
  • 81333 - F1F0 ATP synthase subunit C
  • 0Direct
    100920,100934
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
  • 0Direct
    47473,51695
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 0Direct
    53067,100920
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 0.0000000887Direct
    52833,47616
  • 52833 - Thioredoxin-like
  • 47616 - GST C-terminal domain-like
  • 0.00009503Direct
    57889,57889
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 0.00009939Direct
    52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.0001512Direct
    57903,57903
  • 57903 - FYVE/PHD zinc finger
  • 57903 - FYVE/PHD zinc finger
  • 0.0001674Direct
    54160,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.001066Inherited
    51905,55424
  • 51905 - FAD/NAD(P)-binding domain
  • 55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain
  • 0.01089Inherited
    48065,50729
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0.01316Inherited
    54160,54160
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 0.02136Inherited
    48592,54849
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 0.03356Inherited
    54849,52029
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.03356Inherited
    52374,47323
  • 52374 - Nucleotidylyl transferase
  • 47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
  • 0.1324Inherited
    54928,54928
  • 54928 - RNA-binding domain, RBD
  • 54928 - RNA-binding domain, RBD
  • 0.1707Inherited
    53300,56436
  • 53300 - vWA-like
  • 56436 - C-type lectin-like
  • 0.2101Inherited
    48452,48452
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 1Inherited
    63712,90112
  • 63712 - Nicotinic receptor ligand binding domain-like
  • 90112 - Neurotransmitter-gated ion-channel transmembrane pore
  • 1Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    53067,100920,100934
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
  • 0Direct
    56968,48431,56968
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 48431 - Lipovitellin-phosvitin complex, superhelical domain
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 0Direct
    50729,47473,51695
  • 50729 - PH domain-like
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 0Direct
    53067,53067,100920
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 0.0000000887Direct
    54160,54160,52540
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.001066Inherited
    54160,52540,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.001066Inherited
    48592,54849,52029
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.03356Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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