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Worm Phenotype (WP): protein expression variant

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Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)

Shortest distance to current term (+ for parents, - for children) WP term [WP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + + 6:   Variant [WBPhenotype:0000886] <2>
+ + + + + 5:   physiology variant [WBPhenotype:0000519] <14>(510|587) (510|248|69)
+ + + + 4:   organism physiology variant [WBPhenotype:0000576] <9>(369|431) (372|193|57)
+ + + 3:   organism homeostasis metabolism variant [WBPhenotype:0000577] <16>(361|421) (363|190|56)
+ + 2:   organism metabolism processing variant [WBPhenotype:0000027] <25>(178|190) (182|87|26)
+ 1:   gene expression variant [WBPhenotype:0000717] <11>(127|139) (131|64|20)
0:   protein expression variant [WBPhenotype:0000112] <6>(39|44) (41|19|6)
- 1:   protein modification variant [WBPhenotype:0001382] <9>(13|10) (13|3|0)
- 1:   antibody staining variant [WBPhenotype:0000424] <6>(5|5) (5|2|1)
- 1:   translation variant [WBPhenotype:0000121] <4>(0|0) (0|0|0)
- 1:   level of protein expression variant [WBPhenotype:0001400] <2>(11|12) (11|9|4)
- 1:   pattern protein expression variant [WBPhenotype:0001408] <2>(12|19) (12|6|2)
- 1:   electrophoretic variant protein [WBPhenotype:0000394](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Heme-dependent catalase-like0Direct
14-3-3 protein0Direct
Protein kinase-like (PK-like)0.0000000002756Direct
Arginase/deacetylase0.0000000008264Direct
ARM repeat0.000000001118Direct
SH3-domain0.000000006901Direct
C2 domain (Calcium/lipid-binding domain, CaLB)0.00000003341Direct
Intermediate filament protein, coiled coil region0.00000118Direct
PH domain-like0.000001272Direct
SH2 domain0.0000124Direct
Lamin A/C globular tail domain0.00002424Direct
GTPase activation domain, GAP0.00005868Direct
Integrin domains0.0001573Direct
Cullin homology domain0.0003154Direct
PX domain0.0003154Direct
PDZ domain-like0.000667Direct
CAD & PB1 domains0.0006852Direct
ARID-like0.0006852Direct
DHS-like NAD/FAD-binding domain0.0011Inherited
Cullin repeat-like0.001761Inherited
Sm-like ribonucleoproteins0.00199Inherited
SET domain0.002536Inherited
Second domain of FERM0.005027Inherited
Cysteine-rich domain0.00665Inherited
Frizzled cysteine-rich domain0.01262Inherited
Activating enzymes of the ubiquitin-like proteins0.0155Inherited
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.0155Inherited
Spectrin repeat0.0155Inherited
Cyclin-like0.0168Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.09393Inherited
Riboflavin synthase domain-like0.09393Inherited
Transducin (alpha subunit), insertion domain0.1378Inherited
Actin-like ATPase domain0.1895Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.2375Inherited
Clavaminate synthase-like0.2533Inherited
"Winged helix" DNA-binding domain0.406Inherited
FYVE/PHD zinc finger0.5641Inherited
Translation proteins0.8936Inherited
Chromo domain-like0.9261Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta0Direct
Integrin domains0Direct
Phoshoinositide 3-kinase (PI3K) helical domain0Direct
Cullin repeat0Direct
SCF ubiquitin ligase complex WHB domain0Direct
Inositol polyphosphate 5-phosphatase (IPP5)0Direct
Sir2 family of transcriptional regulators0Direct
14-3-3 protein0Direct
Heme-dependent catalases0Direct
Histone deacetylase, HDAC0Direct
Phoshoinositide 3-kinase (PI3K), catalytic domain0Direct
SH3-domain0.00000002613Direct
Protein kinases, catalytic subunit0.000001653Direct
Intermediate filament protein, coiled coil region0.000003905Direct
PLC-like (P variant)0.000025Direct
EF-hand modules in multidomain proteins0.00002785Direct
PDZ domain0.0001057Direct
SH2 domain0.0001292Direct
Lamin A/C globular tail domain0.0001736Direct
Pleckstrin-homology domain (PH domain)0.0001766Direct
PX domain0.0002987Direct
Cullin homology domain0.0002987Direct
LIM domain0.00102Inherited
Mammalian PLC0.00102Inherited
Histone lysine methyltransferases0.001885Inherited
First domain of FERM0.002909Inherited
Spectrin repeat0.003775Inherited
Third domain of FERM0.003775Inherited
Pumilio repeat0.005045Inherited
Sm motif of small nuclear ribonucleoproteins, SNRNP0.005423Inherited
Second domain of FERM0.007425Inherited
Synaptotagmin-like (S variant)0.007425Inherited
Protein kinase cysteine-rich domain (cys2, phorbol-binding domain)0.007868Inherited
Frizzled cysteine-rich domain0.01157Inherited
G proteins0.01281Inherited
Armadillo repeat0.01301Inherited
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.01468Inherited
Actin/HSP700.0968Inherited
Extended AAA-ATPase domain0.0968Inherited
Transducin (alpha subunit), insertion domain0.1372Inherited
Clathrin coat assembly domain0.1559Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.1559Inherited
Elongation factors0.4855Inherited
PHD domain0.506Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
14-3-3 protein0Direct
Heme-dependent catalase-like0Direct
Protein kinase-like (PK-like)0.0000000002184Direct
Arginase/deacetylase0.0000000006556Direct
ARM repeat0.0000000008874Direct
SH3-domain0.000000005498Direct
C2 domain (Calcium/lipid-binding domain, CaLB)0.0000000267Direct
Intermediate filament protein, coiled coil region0.000000953Direct
PH domain-like0.000001028Direct
SH2 domain0.00001009Direct
Lamin A/C globular tail domain0.00001977Direct
GTPase activation domain, GAP0.00004799Direct
Integrin domains0.0001291Direct
Cullin homology domain0.0002598Direct
PX domain0.0002598Direct
PDZ domain-like0.0005528Direct
CAD & PB1 domains0.0005681Direct
ARID-like0.0005681Direct
PLC-like phosphodiesterases0.0009156Direct
DNase I-like0.0009156Direct
DHS-like NAD/FAD-binding domain0.0009156Direct
Cullin repeat-like0.001473Inherited
Sm-like ribonucleoproteins0.001668Inherited
SET domain0.002135Inherited
Second domain of FERM0.00427Inherited
Cysteine-rich domain0.00567Inherited
Frizzled cysteine-rich domain0.01089Inherited
Activating enzymes of the ubiquitin-like proteins0.01343Inherited
Spectrin repeat0.01343Inherited
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.01343Inherited
Cyclin-like0.01458Inherited
Riboflavin synthase domain-like0.08466Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.08466Inherited
Transducin (alpha subunit), insertion domain0.1255Inherited
Actin-like ATPase domain0.1742Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.22Inherited
Clavaminate synthase-like0.2354Inherited
"Winged helix" DNA-binding domain0.3853Inherited
FYVE/PHD zinc finger0.5423Inherited
Translation proteins0.8783Inherited
Chromo domain-like0.9118Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
75632,46785
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    49562,48371
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 0Direct
    74788,75632
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 0Direct
    64593,74853
  • 64593 - Intermediate filament protein, coiled coil region
  • 74853 - Lamin A/C globular tail domain
  • 0.000006437Direct
    48371,56112
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.00001161Direct
    57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.00007497Direct
    55550,50044
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0.0001291Direct
    47031,50729
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.0008654Direct
    50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0.003188Inherited
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.003188Inherited
    54236,47031
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 0.006519Inherited
    64356,49447
  • 64356 - SNARE-like
  • 49447 - Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor
  • 0.01089Inherited
    46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.01089Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.01836Inherited
    57889,57889
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 0.03404Inherited
    47954,47954
  • 47954 - Cyclin-like
  • 47954 - Cyclin-like
  • 0.04036Inherited
    47895,52540
  • 47895 - Transducin (alpha subunit), insertion domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.1255Inherited
    53067,53067
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 0.1742Inherited
    52540,50447
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 0.4633Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    49562,48371,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    74788,75632,46785
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    57716,57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.0002598Direct
    54236,47031,50729
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.004415Inherited
    46966,46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.01089Inherited
    57424,57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.0201Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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