SUPERFAMILY 1.75 HMM library and genome assignments server

Superfamily is undergoing a server migration - you are now browsing on the new server. Please contact us if you experience any problems.

Worm Phenotype (WP): protein expression variant

(show info)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)

Shortest distance to current term (+ for parents, - for children) WP term [WP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + + 6:   Variant [WBPhenotype:0000886] <5>
+ + + + + 5:   physiology variant [WBPhenotype:0000519] <7>(494|573) (495|248|68)
+ + + + 4:   organism physiology variant [WBPhenotype:0000576] <10>(354|423) (357|200|60)
+ + + 3:   organism homeostasis metabolism variant [WBPhenotype:0000577] <17>(343|412) (348|198|59)
+ + 2:   organism metabolism processing variant [WBPhenotype:0000027] <25>(167|178) (172|81|24)
+ 1:   gene expression variant [WBPhenotype:0000717] <10>(121|132) (128|62|19)
0:   protein expression variant [WBPhenotype:0000112] <6>(38|43) (40|20|6)
- 1:   protein modification variant [WBPhenotype:0001382] <9>(11|9) (11|3|0)
- 1:   antibody staining variant [WBPhenotype:0000424] <6>(5|5) (5|2|1)
- 1:   translation variant [WBPhenotype:0000121] <4>(0|0) (0|0|0)
- 1:   level of protein expression variant [WBPhenotype:0001400] <2>(10|12) (11|11|4)
- 1:   pattern protein expression variant [WBPhenotype:0001408] <2>(11|18) (11|6|2)
- 1:   electrophoretic variant protein [WBPhenotype:0000394](0|0) (0|0|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
14-3-3 protein0Direct
Heme-dependent catalase-like0Direct
Protein kinase-like (PK-like)0.0000000005004Direct
Arginase/deacetylase0.0000000006802Direct
ARM repeat0.00000000208Direct
SH3-domain0.00000001391Direct
C2 domain (Calcium/lipid-binding domain, CaLB)0.00000002293Direct
Intermediate filament protein, coiled coil region0.000001002Direct
SET domain0.000001281Direct
PH domain-like0.000003045Direct
SH2 domain0.0000115Direct
Lamin A/C globular tail domain0.00002116Direct
GTPase activation domain, GAP0.00004791Direct
Integrin domains0.0001465Direct
Cullin homology domain0.0003996Direct
ARID-like0.0006371Direct
CAD & PB1 domains0.0006371Direct
PDZ domain-like0.0009996Direct
DHS-like NAD/FAD-binding domain0.001346Inherited
Cullin repeat-like0.002197Inherited
Sm-like ribonucleoproteins0.002586Inherited
Cysteine-rich domain0.003128Inherited
Second domain of FERM0.004546Inherited
Cyclin-like0.01179Inherited
Frizzled cysteine-rich domain0.01443Inherited
Spectrin repeat0.01812Inherited
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.01812Inherited
Activating enzymes of the ubiquitin-like proteins0.01812Inherited
FYVE/PHD zinc finger0.0893Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.1046Inherited
Riboflavin synthase domain-like0.1046Inherited
Chromo domain-like0.14Inherited
Transducin (alpha subunit), insertion domain0.1564Inherited
Actin-like ATPase domain0.2215Inherited
Clavaminate synthase-like0.2429Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.2596Inherited
"Winged helix" DNA-binding domain0.2613Inherited
Translation proteins0.9244Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Cullin repeat0Direct
Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta0Direct
Sir2 family of transcriptional regulators0Direct
14-3-3 protein0Direct
Phoshoinositide 3-kinase (PI3K) helical domain0Direct
Histone deacetylase, HDAC0Direct
Integrin domains0Direct
Heme-dependent catalases0Direct
Phoshoinositide 3-kinase (PI3K), catalytic domain0Direct
Inositol polyphosphate 5-phosphatase (IPP5)0Direct
SCF ubiquitin ligase complex WHB domain0Direct
SH3-domain0.00000001918Direct
Protein kinases, catalytic subunit0.0000009569Direct
Intermediate filament protein, coiled coil region0.000003508Direct
EF-hand modules in multidomain proteins0.00002627Direct
PLC-like (P variant)0.00003281Direct
SH2 domain0.0001318Direct
PDZ domain0.0001511Direct
Lamin A/C globular tail domain0.0001621Direct
Pleckstrin-homology domain (PH domain)0.0002627Direct
Histone lysine methyltransferases0.0003182Direct
Cullin homology domain0.0003706Direct
LIM domain0.001226Inherited
Mammalian PLC0.001226Inherited
First domain of FERM0.002795Inherited
Third domain of FERM0.003582Inherited
Spectrin repeat0.004048Inherited
Protein kinase cysteine-rich domain (cys2, phorbol-binding domain)0.005204Inherited
Sm motif of small nuclear ribonucleoproteins, SNRNP0.006561Inherited
Second domain of FERM0.006997Inherited
Synaptotagmin-like (S variant)0.006997Inherited
Frizzled cysteine-rich domain0.01317Inherited
Armadillo repeat0.01556Inherited
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.01693Inherited
G proteins0.01949Inherited
Pumilio repeat0.04229Inherited
PHD domain0.1057Inherited
Extended AAA-ATPase domain0.115Inherited
Actin/HSP700.115Inherited
Transducin (alpha subunit), insertion domain0.1555Inherited
Clathrin coat assembly domain0.1718Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.1718Inherited
Elongation factors0.5188Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
Plot tree as:   Download Newick format tree:
(show help)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
14-3-3 protein0Direct
Heme-dependent catalase-like0Direct
Protein kinase-like (PK-like)0.000000000394Direct
Arginase/deacetylase0.0000000005358Direct
ARM repeat0.000000001642Direct
SH3-domain0.00000001102Direct
C2 domain (Calcium/lipid-binding domain, CaLB)0.0000000182Direct
Intermediate filament protein, coiled coil region0.0000008042Direct
SET domain0.000001029Direct
PH domain-like0.000002454Direct
SH2 domain0.000009296Direct
Lamin A/C globular tail domain0.00001715Direct
GTPase activation domain, GAP0.00003896Direct
Integrin domains0.0001195Direct
Cullin homology domain0.0003279Direct
CAD & PB1 domains0.0005248Direct
ARID-like0.0005248Direct
PDZ domain-like0.0008267Direct
Calponin-homology domain, CH-domain0.0008982Direct
DHS-like NAD/FAD-binding domain0.001116Inherited
cAMP-binding domain-like0.001227Inherited
Cullin repeat-like0.001834Inherited
Sm-like ribonucleoproteins0.002164Inherited
Cysteine-rich domain0.002626Inherited
Second domain of FERM0.003836Inherited
Cyclin-like0.0101Inherited
Frizzled cysteine-rich domain0.0124Inherited
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.01563Inherited
Activating enzymes of the ubiquitin-like proteins0.01563Inherited
Spectrin repeat0.01563Inherited
FYVE/PHD zinc finger0.08011Inherited
Riboflavin synthase domain-like0.09431Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.09431Inherited
Chromo domain-like0.1274Inherited
Transducin (alpha subunit), insertion domain0.1426Inherited
Actin-like ATPase domain0.2044Inherited
Clavaminate synthase-like0.2249Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.241Inherited
"Winged helix" DNA-binding domain0.2427Inherited
Translation proteins0.911Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
49562,48371
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 0Direct
    74788,75632
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 0Direct
    75632,46785
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    64593,74853
  • 64593 - Intermediate filament protein, coiled coil region
  • 74853 - Lamin A/C globular tail domain
  • 0.000005699Direct
    48371,56112
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.00001049Direct
    57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.0001076Direct
    55550,50044
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0.0001195Direct
    47031,50729
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.0007712Direct
    50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0.00375Inherited
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.00375Inherited
    54236,47031
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 0.005957Inherited
    46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.0124Inherited
    64356,49447
  • 64356 - SNARE-like
  • 49447 - Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor
  • 0.0124Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.02247Inherited
    47954,47954
  • 47954 - Cyclin-like
  • 47954 - Cyclin-like
  • 0.0275Inherited
    57889,57889
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 0.03909Inherited
    57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.04341Inherited
    47895,52540
  • 47895 - Transducin (alpha subunit), insertion domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.1426Inherited
    53067,53067
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 0.2044Inherited
    52540,50447
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 0.4961Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    49562,48371,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    74788,75632,46785
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    57716,57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.0003279Direct
    54236,47031,50729
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.004031Inherited
    46966,46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.0124Inherited
    57424,57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.01872Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)