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Worm Phenotype (WP): transgene expression variant

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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)

Shortest distance to current term (+ for parents, - for children) WP term [WP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + + 6:   Variant [WBPhenotype:0000886] <2>
+ + + + + 5:   physiology variant [WBPhenotype:0000519] <14>(510|587) (510|248|68)
+ + + + 4:   organism physiology variant [WBPhenotype:0000576] <9>(369|431) (372|193|56)
+ + + 3:   organism homeostasis metabolism variant [WBPhenotype:0000577] <16>(361|421) (363|190|55)
+ + 2:   organism metabolism processing variant [WBPhenotype:0000027] <25>(178|190) (182|87|26)
+ 1:   gene expression variant [WBPhenotype:0000717] <11>(127|139) (131|64|20)
0:   transgene expression variant [WBPhenotype:0000306] <3>(82|99) (85|43|14)
- 1:   level of transgene expression variant [WBPhenotype:0000962] <2>(36|44) (39|12|5)
- 1:   pattern of transgene expression variant [WBPhenotype:0000961] <2>(49|61) (49|29|12)
- 1:   repetitive transgene expression variant [WBPhenotype:0002437] <2>(0|0) (0|0|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Heat shock protein 70kD (HSP70), C-terminal subdomain0Direct
F1F0 ATP synthase subunit C0Direct
FF domain0Direct
JAB1/MPN domain0Direct
Ribosomal protein L10-like0Direct
Helical domain of Sec23/240Direct
TK C-terminal domain-like0Direct
Ribosomal proteins S24e, L23 and L15e0Direct
Cytochrome c0Direct
GroEL-intermediate domain like0Direct
GroEL equatorial domain-like0Direct
MIR domain0Direct
C-terminal, gelsolin-like domain of Sec23/240Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Class II aaRS ABD-related0Direct
Heme-dependent catalase-like0Direct
14-3-3 protein0Direct
Cu,Zn superoxide dismutase-like0Direct
Ribosomal protein L10Direct
Zn-finger domain of Sec23/240Direct
S-adenosylmethionine synthetase0Direct
ValRS/IleRS/LeuRS editing domain0Direct
ISP domain0Direct
SMAD MH1 domain0Direct
Subdomain of clathrin and coatomer appendage domain0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Clathrin adaptor appendage domain0Direct
Epsilon subunit of mitochondrial F1F0-ATP synthase0Direct
Tubulin C-terminal domain-like0Direct
HSP90 C-terminal domain0Direct
Tubulin nucleotide-binding domain-like0Direct
Chromo domain-like0.00000000001859Direct
Chaperone J-domain0.000000003711Direct
Actin-like ATPase domain0.0000002132Direct
Acid proteases0.0000004016Direct
Class II aaRS and biotin synthetases0.0000004016Direct
SNARE-like0.000001609Direct
Translation proteins0.000001822Direct
CCCH zinc finger0.00001209Direct
Translation proteins SH3-like domain0.00001776Direct
Heat shock protein 70kD (HSP70), peptide-binding domain0.00002643Direct
Hect, E3 ligase catalytic domain0.00002643Direct
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.00002737Direct
B-box zinc-binding domain0.00003681Direct
Cyclophilin-like0.0001029Direct
HMG-box0.000267Direct
Sm-like ribonucleoproteins0.000267Direct
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0.0005911Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase0.001137Inherited
Activating enzymes of the ubiquitin-like proteins0.001827Inherited
PYP-like sensor domain (PAS domain)0.001827Inherited
FKBP-like0.002089Inherited
4Fe-4S ferredoxins0.003872Inherited
Frizzled cysteine-rich domain0.003872Inherited
RING/U-box0.004742Inherited
Single hybrid motif0.005447Inherited
Zn-binding ribosomal proteins0.005485Inherited
Saposin0.005558Inherited
HIT/MYND zinc finger-like0.009731Inherited
ADC-like0.01289Inherited
Cdc48 domain 2-like0.01289Inherited
ClpP/crotonase0.02278Inherited
Tubby C-terminal domain-like0.04462Inherited
S15/NS1 RNA-binding domain0.04462Inherited
UBC-like0.04617Inherited
HLH, helix-loop-helix DNA-binding domain0.06753Inherited
HSP20-like chaperones0.111Inherited
Cysteine proteinases0.1165Inherited
Nucleotidylyl transferase0.1813Inherited
SET domain0.2127Inherited
p53-like transcription factors0.2312Inherited
Homeodomain-like0.363Inherited
Tudor/PWWP/MBT0.3695Inherited
GroEL apical domain-like0.3695Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.3898Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.4634Inherited
L30e-like0.5166Inherited
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.5777Inherited
Leucine zipper domain0.6246Inherited
Nuclear receptor ligand-binding domain0.6808Inherited
P-loop containing nucleoside triphosphate hydrolases0.8053Inherited
Protein kinase-like (PK-like)1Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
PDI-like0Direct
CAT-like0Direct
MIR domain0Direct
Ribosomal protein L10Direct
beta-sandwich domain of Sec23/240Direct
a tRNA synthase domain0Direct
Heat shock protein 90, HSP90, N-terminal domain0Direct
ValRS/IleRS/LeuRS editing domain0Direct
Brix domain0Direct
Heme-dependent catalases0Direct
Epsilon subunit of mitochondrial F1F0-ATP synthase0Direct
FF domain0Direct
Hsp90 middle domain0Direct
Tubulin, GTPase domain0Direct
Cu,Zn superoxide dismutase-like0Direct
Quinoprotein alcohol dehydrogenase-like0Direct
Helical domain of Sec23/240Direct
L30e/L7ae ribosomal proteins0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Acyl-carrier protein (ACP)0Direct
Zn-finger domain of Sec23/240Direct
HSP200Direct
Group II chaperonin (CCT, TRIC), intermediate domain0Direct
Ubiquitin carboxyl-terminal hydrolase UCH-L0Direct
Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain0Direct
RNA-polymerase beta0Direct
14-3-3 protein0Direct
p120GAP domain-like0Direct
Proteasome subunits0Direct
Phoshoinositide 3-kinase (PI3K) helical domain0Direct
Clathrin coat assembly domain0Direct
Erythroid transcription factor GATA-10Direct
Mammalian PLC0Direct
Chromo domain0Direct
Trunk domain of Sec23/240Direct
SMAD MH1 domain0Direct
HSP90 C-terminal domain0Direct
Group II chaperonin (CCT, TRIC), ATPase domain0Direct
F1F0 ATP synthase subunit C0Direct
Integrin domains0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
S-adenosylmethionine synthetase0Direct
Tubulin, C-terminal domain0Direct
RecA protein-like (ATPase-domain)0Direct
Heat shock protein 70kD (HSP70), C-terminal subdomain0Direct
Anticodon-binding domain of Class II aaRS0Direct
C-terminal, gelsolin-like domain of Sec23/240Direct
Actin/HSP700.0000000002053Direct
UBC-related0.000000003791Direct
Forkhead DNA-binding domain0.00000003412Direct
PHD domain0.0000001134Direct
Chaperone J-domain0.0000001266Direct
Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain0.0000001356Direct
Pepsin-like0.0000003954Direct
Papain-like0.00000424Direct
Ubiquitin carboxyl-terminal hydrolase, UCH0.000007279Direct
Hect, E3 ligase catalytic domain0.00008526Direct
CCCH zinc finger0.0001205Direct
PLC-like (P variant)0.0002075Direct
B-box zinc-binding domain0.0002094Direct
SMAD domain0.0002566Direct
Translational machinery components0.0002566Direct
Heat shock protein 70kD (HSP70), peptide-binding domain0.0002566Direct
Cyclophilin (peptidylprolyl isomerase)0.0004966Direct
TBP-associated factors, TAFs0.000838Direct
Ubiquitin-related0.0009381Direct
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0.001537Inherited
Sm motif of small nuclear ribonucleoproteins, SNRNP0.002463Inherited
Extended PAW domain0.002636Inherited
FKBP immunophilin/proline isomerase0.005192Inherited
Ubiquitin activating enzymes (UBA)0.0067Inherited
Transforming growth factor (TGF)-beta0.0067Inherited
Frizzled cysteine-rich domain0.0067Inherited
Biotinyl/lipoyl-carrier proteins and domains0.01294Inherited
Cdc48 domain 2-like0.01959Inherited
Anticodon-binding domain0.01959Inherited
Biotin dependent carboxylase carboxyltransferase domain0.01959Inherited
Cdc48 N-terminal domain-like0.01959Inherited
HLH, helix-loop-helix DNA-binding domain0.06102Inherited
DEP domain0.06642Inherited
RING finger domain, C3HC40.134Inherited
Homeodomain0.188Inherited
Dual specificity phosphatase-like0.1897Inherited
Class I aminoacyl-tRNA synthetases (RS), catalytic domain0.2147Inherited
Group II chaperonin (CCT, TRIC), apical domain0.3931Inherited
Clathrin adaptor core protein0.4962Inherited
N-acetyl transferase, NAT0.4962Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.4962Inherited
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.5558Inherited
Histone lysine methyltransferases0.563Inherited
Leucine zipper domain0.6068Inherited
Adenain-like0.6242Inherited
Cyclin0.6989Inherited
MIF4G domain-like0.6993Inherited
Armadillo repeat0.7465Inherited
Nucleosome core histones0.8712Inherited
Nuclear receptor1Inherited
Nuclear receptor ligand-binding domain1Inherited
Protein kinases, catalytic subunit1Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Ribosomal protein L10-like0Direct
F1F0 ATP synthase subunit C0Direct
GroEL equatorial domain-like0Direct
Epsilon subunit of mitochondrial F1F0-ATP synthase0Direct
ValRS/IleRS/LeuRS editing domain0Direct
Clathrin adaptor appendage domain0Direct
Heme-dependent catalase-like0Direct
C-terminal, gelsolin-like domain of Sec23/240Direct
14-3-3 protein0Direct
S-adenosylmethionine synthetase0Direct
Ribosomal proteins S24e, L23 and L15e0Direct
Tubulin C-terminal domain-like0Direct
Heat shock protein 70kD (HSP70), C-terminal subdomain0Direct
SMAD MH1 domain0Direct
HSP90 C-terminal domain0Direct
JAB1/MPN domain0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Class II aaRS ABD-related0Direct
Tubulin nucleotide-binding domain-like0Direct
Ribosomal protein L10Direct
GroEL-intermediate domain like0Direct
Subdomain of clathrin and coatomer appendage domain0Direct
Helical domain of Sec23/240Direct
FF domain0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
ISP domain0Direct
Cytochrome c0Direct
MIR domain0Direct
TK C-terminal domain-like0Direct
Zn-finger domain of Sec23/240Direct
Cu,Zn superoxide dismutase-like0Direct
Chromo domain-like0.00000000001469Direct
Chaperone J-domain0.000000002954Direct
Actin-like ATPase domain0.0000001713Direct
Class II aaRS and biotin synthetases0.0000003234Direct
Acid proteases0.0000003234Direct
SNARE-like0.000001302Direct
Translation proteins0.000001476Direct
CCCH zinc finger0.000009843Direct
Translation proteins SH3-like domain0.00001447Direct
Hect, E3 ligase catalytic domain0.00002158Direct
Heat shock protein 70kD (HSP70), peptide-binding domain0.00002158Direct
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.00002234Direct
B-box zinc-binding domain0.00003006Direct
Cyclophilin-like0.00008431Direct
HMG-box0.0002198Direct
Sm-like ribonucleoproteins0.0002198Direct
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0.0004897Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase0.0009476Direct
FAD/NAD-linked reductases, dimerisation (C-terminal) domain0.0009476Direct
PYP-like sensor domain (PAS domain)0.00153Inherited
Activating enzymes of the ubiquitin-like proteins0.00153Inherited
FKBP-like0.001753Inherited
4Fe-4S ferredoxins0.00328Inherited
Frizzled cysteine-rich domain0.00328Inherited
RING/U-box0.004026Inherited
Single hybrid motif0.004631Inherited
Zn-binding ribosomal proteins0.004664Inherited
Saposin0.004728Inherited
HIT/MYND zinc finger-like0.008364Inherited
Cdc48 domain 2-like0.01114Inherited
ADC-like0.01114Inherited
ClpP/crotonase0.01988Inherited
Tubby C-terminal domain-like0.03944Inherited
S15/NS1 RNA-binding domain0.03944Inherited
UBC-like0.04083Inherited
HLH, helix-loop-helix DNA-binding domain0.06029Inherited
HSP20-like chaperones0.1005Inherited
Cysteine proteinases0.1056Inherited
Nucleotidylyl transferase0.1666Inherited
SET domain0.1964Inherited
p53-like transcription factors0.214Inherited
Homeodomain-like0.3427Inherited
GroEL apical domain-like0.3492Inherited
Tudor/PWWP/MBT0.3492Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.3693Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.4423Inherited
L30e-like0.4948Inherited
Cyclin-like0.5198Inherited
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.5558Inherited
Leucine zipper domain0.6026Inherited
Nuclear receptor ligand-binding domain0.6595Inherited
Histone-fold0.7065Inherited
P-loop containing nucleoside triphosphate hydrolases0.7869Inherited
Protein kinase-like (PK-like)1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
47473,51695
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 0Direct
    50677,52374
  • 50677 - ValRS/IleRS/LeuRS editing domain
  • 52374 - Nucleotidylyl transferase
  • 0Direct
    48592,54849
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 0Direct
    81333,81333
  • 81333 - F1F0 ATP synthase subunit C
  • 81333 - F1F0 ATP synthase subunit C
  • 0Direct
    54495,46934
  • 54495 - UBC-like
  • 46934 - UBA-like
  • 0Direct
    81811,82754
  • 81811 - Helical domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0Direct
    100920,100934
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
  • 0Direct
    144232,82199
  • 144232 - HIT/MYND zinc finger-like
  • 82199 - SET domain
  • 0Direct
    50729,47473
  • 50729 - PH domain-like
  • 47473 - EF-hand
  • 0Direct
    54849,52029
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0Direct
    52518,52922
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 52922 - TK C-terminal domain-like
  • 0Direct
    52540,47917
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase
  • 0Direct
    49562,48371
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 0Direct
    54534,54534
  • 54534 - FKBP-like
  • 54534 - FKBP-like
  • 0Direct
    55681,52954
  • 55681 - Class II aaRS and biotin synthetases
  • 52954 - Class II aaRS ABD-related
  • 0Direct
    81698,81698
  • 81698 - FF domain
  • 81698 - FF domain
  • 0Direct
    55973,55973
  • 55973 - S-adenosylmethionine synthetase
  • 55973 - S-adenosylmethionine synthetase
  • 0Direct
    55785,55785
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0Direct
    57903,51197
  • 57903 - FYVE/PHD zinc finger
  • 51197 - Clavaminate synthase-like
  • 0Direct
    54585,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    54160,54160
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 0Direct
    57903,82199
  • 57903 - FYVE/PHD zinc finger
  • 82199 - SET domain
  • 0Direct
    46785,46785
  • 46785 - "Winged helix" DNA-binding domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    51695,49562
  • 51695 - PLC-like phosphodiesterases
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0Direct
    50692,54585
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 0Direct
    82919,53300
  • 82919 - Zn-finger domain of Sec23/24
  • 53300 - vWA-like
  • 0Direct
    64356,49447
  • 64356 - SNARE-like
  • 49447 - Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor
  • 0Direct
    57863,48403
  • 57863 - ArfGap/RecO-like zinc finger
  • 48403 - Ankyrin repeat
  • 0Direct
    54160,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    52490,55307
  • 52490 - Tubulin nucleotide-binding domain-like
  • 55307 - Tubulin C-terminal domain-like
  • 0Direct
    49348,55711
  • 49348 - Clathrin adaptor appendage domain
  • 55711 - Subdomain of clathrin and coatomer appendage domain
  • 0Direct
    53067,53067
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 0.0000000008531Direct
    53067,100920
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 0.00002158Direct
    50447,50465
  • 50447 - Translation proteins
  • 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
  • 0.0004897Direct
    52540,50447
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 0.0005704Direct
    51045,51045
  • 51045 - WW domain
  • 51045 - WW domain
  • 0.0009476Direct
    51905,55424
  • 51905 - FAD/NAD(P)-binding domain
  • 55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain
  • 0.0009476Direct
    57850,57845
  • 57850 - RING/U-box
  • 57845 - B-box zinc-binding domain
  • 0.001619Inherited
    90229,90229
  • 90229 - CCCH zinc finger
  • 90229 - CCCH zinc finger
  • 0.00297Inherited
    52833,52833
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 0.004115Inherited
    57850,57850
  • 57850 - RING/U-box
  • 57850 - RING/U-box
  • 0.01904Inherited
    50249,55681
  • 50249 - Nucleic acid-binding proteins
  • 55681 - Class II aaRS and biotin synthetases
  • 0.03944Inherited
    48452,48452
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 0.5198Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    54160,54160,52540
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    48452,48452,48452
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 0Direct
    49562,48371,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    53067,100920,100934
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
  • 0Direct
    50729,47473,51695
  • 50729 - PH domain-like
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 0Direct
    55973,55973,55973
  • 55973 - S-adenosylmethionine synthetase
  • 55973 - S-adenosylmethionine synthetase
  • 55973 - S-adenosylmethionine synthetase
  • 0Direct
    50692,54585,52540
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    54585,52540,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    48592,54849,52029
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0Direct
    54160,52540,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    53067,53067,100920
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 0.00002158Direct
    52540,50447,50465
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
  • 0.0004897Direct
    52833,52833,52833
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 0.004631Inherited
    57850,57850,57850
  • 57850 - RING/U-box
  • 57850 - RING/U-box
  • 57850 - RING/U-box
  • 0.004919Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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