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Worm Phenotype (WP): transgene expression variant

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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)

Shortest distance to current term (+ for parents, - for children) WP term [WP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + + 6:   Variant [WBPhenotype:0000886] <5>
+ + + + + 5:   physiology variant [WBPhenotype:0000519] <7>(494|573) (495|248|68)
+ + + + 4:   organism physiology variant [WBPhenotype:0000576] <10>(354|423) (357|200|60)
+ + + 3:   organism homeostasis metabolism variant [WBPhenotype:0000577] <17>(343|412) (348|198|59)
+ + 2:   organism metabolism processing variant [WBPhenotype:0000027] <25>(167|178) (172|81|24)
+ 1:   gene expression variant [WBPhenotype:0000717] <10>(121|132) (128|62|19)
0:   transgene expression variant [WBPhenotype:0000306] <3>(83|93) (89|41|13)
- 1:   level of transgene expression variant [WBPhenotype:0000962] <2>(35|43) (38|13|6)
- 1:   pattern of transgene expression variant [WBPhenotype:0000961] <2>(47|56) (51|26|11)
- 1:   repetitive transgene expression variant [WBPhenotype:0002437] <2>(0|0) (0|0|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
14-3-3 protein0Direct
Class II aaRS ABD-related0Direct
F1F0 ATP synthase subunit C0Direct
Helical domain of Sec23/240Direct
Subdomain of clathrin and coatomer appendage domain0Direct
TK C-terminal domain-like0Direct
ValRS/IleRS/LeuRS editing domain0Direct
S-adenosylmethionine synthetase0Direct
Zn-finger domain of Sec23/240Direct
GroEL-intermediate domain like0Direct
Heat shock protein 70kD (HSP70), C-terminal subdomain0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
FF domain0Direct
Cytochrome c0Direct
SMAD MH1 domain0Direct
GroEL equatorial domain-like0Direct
HSP90 C-terminal domain0Direct
Ribosomal protein L10Direct
Tubulin C-terminal domain-like0Direct
Tubulin nucleotide-binding domain-like0Direct
JAB1/MPN domain0Direct
Ribosomal protein L10-like0Direct
Clathrin adaptor appendage domain0Direct
Epsilon subunit of mitochondrial F1F0-ATP synthase0Direct
Heme-dependent catalase-like0Direct
Histone-fold0Direct
Cu,Zn superoxide dismutase-like0Direct
MIR domain0Direct
Ribosomal proteins S24e, L23 and L15e0Direct
C-terminal, gelsolin-like domain of Sec23/240Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
ISP domain0Direct
Chaperone J-domain0.000000001171Direct
Actin-like ATPase domain0.00000007253Direct
Class II aaRS and biotin synthetases0.0000001864Direct
Acid proteases0.0000007911Direct
Translation proteins0.0000008081Direct
SNARE-like0.0000008828Direct
CCCH zinc finger0.000005572Direct
B-box zinc-binding domain0.000006131Direct
Translation proteins SH3-like domain0.00001081Direct
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.00001282Direct
Heat shock protein 70kD (HSP70), peptide-binding domain0.00001742Direct
Hect, E3 ligase catalytic domain0.00001742Direct
Cyclophilin-like0.00005964Direct
Sm-like ribonucleoproteins0.0001583Direct
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0.0004175Direct
HMG-box0.0004262Direct
RING/U-box0.0007689Direct
FAD/NAD-linked reductases, dimerisation (C-terminal) domain0.0008701Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase0.0008701Direct
Sec1/munc18-like (SM) proteins0.0008701Direct
PYP-like sensor domain (PAS domain)0.001359Inherited
Activating enzymes of the ubiquitin-like proteins0.001359Inherited
FKBP-like0.001503Inherited
4Fe-4S ferredoxins0.00311Inherited
Frizzled cysteine-rich domain0.00311Inherited
Saposin0.003468Inherited
Single hybrid motif0.003977Inherited
Zn-binding ribosomal proteins0.004275Inherited
ADC-like0.0109Inherited
Cdc48 domain 2-like0.0109Inherited
ClpP/crotonase0.03369Inherited
Tubby C-terminal domain-like0.03816Inherited
S15/NS1 RNA-binding domain0.03816Inherited
UBC-like0.05642Inherited
HLH, helix-loop-helix DNA-binding domain0.08048Inherited
HSP20-like chaperones0.1285Inherited
Cysteine proteinases0.242Inherited
p53-like transcription factors0.2555Inherited
Nuclear receptor ligand-binding domain0.3847Inherited
GroEL apical domain-like0.3975Inherited
ENTH/VHS domain0.3975Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.465Inherited
Homeodomain-like0.4695Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.4917Inherited
Nucleotidylyl transferase0.5036Inherited
L30e-like0.5475Inherited
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.6052Inherited
Chromo domain-like0.6052Inherited
Leucine zipper domain0.6624Inherited
P-loop containing nucleoside triphosphate hydrolases0.9475Inherited
FYVE/PHD zinc finger1Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Clathrin coat assembly domain0Direct
Trunk domain of Sec23/240Direct
Epsilon subunit of mitochondrial F1F0-ATP synthase0Direct
Acyl-carrier protein (ACP)0Direct
beta-sandwich domain of Sec23/240Direct
RecA protein-like (ATPase-domain)0Direct
Brix domain0Direct
ValRS/IleRS/LeuRS editing domain0Direct
Ribosomal protein L10Direct
Helical domain of Sec23/240Direct
F1F0 ATP synthase subunit C0Direct
SMAD MH1 domain0Direct
Quinoprotein alcohol dehydrogenase-like0Direct
14-3-3 protein0Direct
Hsp90 middle domain0Direct
Heat shock protein 90, HSP90, N-terminal domain0Direct
Heat shock protein 70kD (HSP70), C-terminal subdomain0Direct
a tRNA synthase domain0Direct
Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain0Direct
Group II chaperonin (CCT, TRIC), ATPase domain0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Phoshoinositide 3-kinase (PI3K) helical domain0Direct
HSP200Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
PDI-like0Direct
Ubiquitin carboxyl-terminal hydrolase UCH-L0Direct
Erythroid transcription factor GATA-10Direct
HSP90 C-terminal domain0Direct
Group II chaperonin (CCT, TRIC), intermediate domain0Direct
Proteasome subunits0Direct
Heme-dependent catalases0Direct
Tubulin, C-terminal domain0Direct
RNA-polymerase beta0Direct
Anticodon-binding domain of Class II aaRS0Direct
C-terminal, gelsolin-like domain of Sec23/240Direct
p120GAP domain-like0Direct
S-adenosylmethionine synthetase0Direct
MIR domain0Direct
Mammalian PLC0Direct
FF domain0Direct
CAT-like0Direct
Tubulin, GTPase domain0Direct
L30e/L7ae ribosomal proteins0Direct
Cu,Zn superoxide dismutase-like0Direct
Zn-finger domain of Sec23/240Direct
Nucleosome core histones0.00000000006089Direct
Actin/HSP700.000000000092Direct
UBC-related0.00000000169Direct
Chaperone J-domain0.00000005618Direct
Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain0.00000007607Direct
Pepsin-like0.00000007607Direct
Ubiquitin carboxyl-terminal hydrolase, UCH0.0000001698Direct
Papain-like0.000002186Direct
B-box zinc-binding domain0.00004452Direct
Hect, E3 ligase catalytic domain0.0000635Direct
CCCH zinc finger0.00007069Direct
PLC-like (P variant)0.0001517Direct
Translational machinery components0.0001985Direct
Heat shock protein 70kD (HSP70), peptide-binding domain0.0001985Direct
SMAD domain0.0001985Direct
Cyclophilin (peptidylprolyl isomerase)0.0003409Direct
Ubiquitin-related0.0005791Direct
TBP-associated factors, TAFs0.0006221Direct
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0.001203Inherited
Sm motif of small nuclear ribonucleoproteins, SNRNP0.001849Inherited
Extended PAW domain0.004009Inherited
FKBP immunophilin/proline isomerase0.004129Inherited
Frizzled cysteine-rich domain0.005781Inherited
Ubiquitin activating enzymes (UBA)0.005781Inherited
Transforming growth factor (TGF)-beta0.005781Inherited
Biotinyl/lipoyl-carrier proteins and domains0.01044Inherited
Cdc48 N-terminal domain-like0.0174Inherited
Cdc48 domain 2-like0.0174Inherited
Anticodon-binding domain0.0174Inherited
RING finger domain, C3HC40.04229Inherited
DEP domain0.05972Inherited
HLH, helix-loop-helix DNA-binding domain0.07661Inherited
Calmodulin-like0.109Inherited
Dual specificity phosphatase-like0.2194Inherited
Class I aminoacyl-tRNA synthetases (RS), catalytic domain0.2455Inherited
Homeodomain0.2616Inherited
Cyclin0.3864Inherited
Group II chaperonin (CCT, TRIC), apical domain0.4297Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.5334Inherited
Clathrin adaptor core protein0.5334Inherited
N-acetyl transferase, NAT0.5914Inherited
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.5914Inherited
Leucine zipper domain0.6561Inherited
MIF4G domain-like0.7326Inherited
Armadillo repeat0.7898Inherited
Nuclear receptor ligand-binding domain0.9081Inherited
Nuclear receptor0.9158Inherited
PHD domain0.979Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
GroEL equatorial domain-like0Direct
Cu,Zn superoxide dismutase-like0Direct
Heat shock protein 70kD (HSP70), C-terminal subdomain0Direct
MIR domain0Direct
Ribosomal protein L10Direct
Zn-finger domain of Sec23/240Direct
Class II aaRS ABD-related0Direct
ValRS/IleRS/LeuRS editing domain0Direct
Epsilon subunit of mitochondrial F1F0-ATP synthase0Direct
TK C-terminal domain-like0Direct
Tubulin nucleotide-binding domain-like0Direct
Helical domain of Sec23/240Direct
Histone-fold0Direct
Subdomain of clathrin and coatomer appendage domain0Direct
Tubulin C-terminal domain-like0Direct
14-3-3 protein0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
GroEL-intermediate domain like0Direct
S-adenosylmethionine synthetase0Direct
Ribosomal proteins S24e, L23 and L15e0Direct
Clathrin adaptor appendage domain0Direct
Ribosomal protein L10-like0Direct
FF domain0Direct
F1F0 ATP synthase subunit C0Direct
Cytochrome c0Direct
JAB1/MPN domain0Direct
SMAD MH1 domain0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
C-terminal, gelsolin-like domain of Sec23/240Direct
HSP90 C-terminal domain0Direct
Heme-dependent catalase-like0Direct
ISP domain0Direct
Chaperone J-domain0.0000000009231Direct
Actin-like ATPase domain0.00000005765Direct
Class II aaRS and biotin synthetases0.0000001486Direct
Acid proteases0.0000006341Direct
Translation proteins0.0000006478Direct
SNARE-like0.0000007079Direct
CCCH zinc finger0.000004492Direct
B-box zinc-binding domain0.000004946Direct
Translation proteins SH3-like domain0.000008734Direct
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.00001037Direct
Hect, E3 ligase catalytic domain0.00001411Direct
Heat shock protein 70kD (HSP70), peptide-binding domain0.00001411Direct
Cyclophilin-like0.00004849Direct
Sm-like ribonucleoproteins0.0001291Direct
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0.0003428Direct
HMG-box0.0003501Direct
RING/U-box0.0006347Direct
Sec1/munc18-like (SM) proteins0.0007189Direct
FAD/NAD-linked reductases, dimerisation (C-terminal) domain0.0007189Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase0.0007189Direct
Ribosomal protein S5 domain 2-like0.0009046Direct
Activating enzymes of the ubiquitin-like proteins0.001127Inherited
PYP-like sensor domain (PAS domain)0.001127Inherited
FKBP-like0.001249Inherited
4Fe-4S ferredoxins0.002611Inherited
Frizzled cysteine-rich domain0.002611Inherited
Saposin0.002916Inherited
Single hybrid motif0.003348Inherited
Zn-binding ribosomal proteins0.003605Inherited
Cdc48 domain 2-like0.009321Inherited
ADC-like0.009321Inherited
Lipovitellin-phosvitin complex, superhelical domain0.01118Inherited
Lipovitellin-phosvitin complex; beta-sheet shell regions0.01118Inherited
ClpP/crotonase0.02949Inherited
S15/NS1 RNA-binding domain0.03347Inherited
Tubby C-terminal domain-like0.03347Inherited
UBC-like0.04997Inherited
HLH, helix-loop-helix DNA-binding domain0.07197Inherited
Thiamin diphosphate-binding fold (THDP-binding)0.09549Inherited
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.09549Inherited
HSP20-like chaperones0.1166Inherited
Cysteine proteinases0.2241Inherited
p53-like transcription factors0.2371Inherited
Nuclear receptor ligand-binding domain0.3637Inherited
ENTH/VHS domain0.3762Inherited
GroEL apical domain-like0.3762Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.4432Inherited
Homeodomain-like0.4476Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.4701Inherited
Nucleotidylyl transferase0.4815Inherited
L30e-like0.5251Inherited
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.5829Inherited
Chromo domain-like0.5829Inherited
Leucine zipper domain0.6407Inherited
P-loop containing nucleoside triphosphate hydrolases0.9352Inherited
FYVE/PHD zinc finger1Inherited
ARM repeat1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
51695,49562
  • 51695 - PLC-like phosphodiesterases
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0Direct
    48592,54849
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 0Direct
    54495,46934
  • 54495 - UBC-like
  • 46934 - UBA-like
  • 0Direct
    50692,54585
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 0Direct
    57863,48403
  • 57863 - ArfGap/RecO-like zinc finger
  • 48403 - Ankyrin repeat
  • 0Direct
    64356,49447
  • 64356 - SNARE-like
  • 49447 - Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor
  • 0Direct
    52518,52922
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 52922 - TK C-terminal domain-like
  • 0Direct
    54849,52029
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0Direct
    81698,81698
  • 81698 - FF domain
  • 81698 - FF domain
  • 0Direct
    55785,55785
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0Direct
    47473,51695
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 0Direct
    81333,81333
  • 81333 - F1F0 ATP synthase subunit C
  • 81333 - F1F0 ATP synthase subunit C
  • 0Direct
    49562,48371
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 0Direct
    55973,55973
  • 55973 - S-adenosylmethionine synthetase
  • 55973 - S-adenosylmethionine synthetase
  • 0Direct
    49348,55711
  • 49348 - Clathrin adaptor appendage domain
  • 55711 - Subdomain of clathrin and coatomer appendage domain
  • 0Direct
    55681,52954
  • 55681 - Class II aaRS and biotin synthetases
  • 52954 - Class II aaRS ABD-related
  • 0Direct
    54534,54534
  • 54534 - FKBP-like
  • 54534 - FKBP-like
  • 0Direct
    81811,82754
  • 81811 - Helical domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0Direct
    50729,47473
  • 50729 - PH domain-like
  • 47473 - EF-hand
  • 0Direct
    100920,100934
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
  • 0Direct
    82919,53300
  • 82919 - Zn-finger domain of Sec23/24
  • 53300 - vWA-like
  • 0Direct
    46785,46785
  • 46785 - "Winged helix" DNA-binding domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    52490,55307
  • 52490 - Tubulin nucleotide-binding domain-like
  • 55307 - Tubulin C-terminal domain-like
  • 0Direct
    50677,52374
  • 50677 - ValRS/IleRS/LeuRS editing domain
  • 52374 - Nucleotidylyl transferase
  • 0Direct
    52540,47917
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase
  • 0Direct
    54585,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    53067,53067
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 0.0000000002616Direct
    53067,100920
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 0.00001411Direct
    50447,50465
  • 50447 - Translation proteins
  • 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
  • 0.0003428Direct
    52540,50447
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 0.0003501Direct
    57850,57845
  • 57850 - RING/U-box
  • 57845 - B-box zinc-binding domain
  • 0.0004203Direct
    51045,51045
  • 51045 - WW domain
  • 51045 - WW domain
  • 0.0007189Direct
    51905,55424
  • 51905 - FAD/NAD(P)-binding domain
  • 55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain
  • 0.0007189Direct
    90229,90229
  • 90229 - CCCH zinc finger
  • 90229 - CCCH zinc finger
  • 0.001944Inherited
    52833,52833
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 0.002881Inherited
    63380,52343
  • 63380 - Riboflavin synthase domain-like
  • 52343 - Ferredoxin reductase-like, C-terminal NADP-linked domain
  • 0.01118Inherited
    48431,56968
  • 48431 - Lipovitellin-phosvitin complex, superhelical domain
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 0.01118Inherited
    56968,48431
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 48431 - Lipovitellin-phosvitin complex, superhelical domain
  • 0.01118Inherited
    57850,57850
  • 57850 - RING/U-box
  • 57850 - RING/U-box
  • 0.01418Inherited
    50249,55681
  • 50249 - Nucleic acid-binding proteins
  • 55681 - Class II aaRS and biotin synthetases
  • 0.03347Inherited
    48452,48452
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 0.5598Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    48592,54849,52029
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0Direct
    50692,54585,52540
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    49562,48371,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    48452,48452,48452
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 0Direct
    55973,55973,55973
  • 55973 - S-adenosylmethionine synthetase
  • 55973 - S-adenosylmethionine synthetase
  • 55973 - S-adenosylmethionine synthetase
  • 0Direct
    50729,47473,51695
  • 50729 - PH domain-like
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 0Direct
    54585,52540,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    53067,100920,100934
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
  • 0Direct
    53067,53067,100920
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 0.00001411Direct
    52540,50447,50465
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
  • 0.0003428Direct
    52833,52833,52833
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 0.003348Inherited
    57850,57850,57850
  • 57850 - RING/U-box
  • 57850 - RING/U-box
  • 57850 - RING/U-box
  • 0.003686Inherited
    56968,48431,56968
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 48431 - Lipovitellin-phosvitin complex, superhelical domain
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 0.01118Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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