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Worm Phenotype (WP): retarded heterochronic variations

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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)

Shortest distance to current term (+ for parents, - for children) WP term [WP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   Variant [WBPhenotype:0000886] <5>
+ + + 3:   development variant [WBPhenotype:0000518] <4>(511|586) (511|253|70)
+ + 2:   organism development variant [WBPhenotype:0000531] <10>(505|584) (505|253|70)
+ 1:   developmental timing variant [WBPhenotype:0000033] <3>(146|210) (146|100|29)
0:   retarded heterochronic variations [WBPhenotype:0000438] <14>(146|209) (146|97|29)
- 1:   developmental delay [WBPhenotype:0000848] <2>(2|1) (2|1|0)
- 1:   cell cleavage delayed [WBPhenotype:0000267] <1>(0|0) (0|0|0)
- 1:   slow development [WBPhenotype:0000674] <1>(4|4) (4|1|0)
- 1:   P0 spindle rotation delayed early emb [WBPhenotype:0001109](0|0) (0|0|0)
- 1:   cell corpse appearance delayed [WBPhenotype:0010003](2|2) (2|0|0)
- 1:   cell cycle delayed [WBPhenotype:0000318](0|0) (0|0|0)
- 1:   cell cycle slow early emb [WBPhenotype:0001119](0|0) (0|0|0)
- 1:   cell division slow [WBPhenotype:0000363](0|0) (0|0|0)
- 1:   delayed hatching [WBPhenotype:0000404](2|2) (2|1|0)
- 1:   larval development retarded [WBPhenotype:0000442](0|0) (0|0|0)
- 1:   larval growth slow [WBPhenotype:0000685](0|0) (0|0|0)
- 1:   late stage egg laid [WBPhenotype:0001483](1|0) (1|0|0)
- 1:   slow growth [WBPhenotype:0000031](129|191) (129|92|28)
- 1:   spermatogenesis delayed [WBPhenotype:0000356](0|0) (0|0|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain0Direct
Phoshotransferase/anion transport protein0Direct
Cytochrome c0Direct
Radical SAM enzymes0Direct
Heme-dependent catalase-like0Direct
Troponin coil-coiled subunits0Direct
Epsilon subunit of mitochondrial F1F0-ATP synthase0Direct
Hedgehog/intein (Hint) domain0Direct
Terpenoid cyclases/Protein prenyltransferases0Direct
Domain of poly(ADP-ribose) polymerase0Direct
LDH C-terminal domain-like0Direct
LEM domain0Direct
DNA repair protein MutS, domain III0Direct
SPOC domain-like0Direct
Thiamin diphosphate-binding fold (THDP-binding)0Direct
Ran binding protein zinc finger-like0Direct
Cu,Zn superoxide dismutase-like0Direct
FtsH protease domain-like0Direct
Thyroglobulin type-1 domain0Direct
Tryptophan synthase beta subunit-like PLP-dependent enzymes0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Cdc48 domain 2-like0Direct
Transducin (heterotrimeric G protein), gamma chain0Direct
Cation efflux protein cytoplasmic domain-like0Direct
PHM/PNGase F0Direct
Glycolipid transfer protein, GLTP0Direct
PAP/Archaeal CCA-adding enzyme, C-terminal domain0Direct
Carbohydrate phosphatase0Direct
Ribulose-phoshate binding barrel0Direct
Tubby C-terminal domain-like0Direct
Ribosomal protein L10-like0Direct
Mitochondrial carrier0Direct
PreATP-grasp domain0Direct
HSP90 C-terminal domain0Direct
Creatinase/prolidase N-terminal domain0Direct
Bacterial exopeptidase dimerisation domain0Direct
Carbon-nitrogen hydrolase0Direct
L-aspartase-like0Direct
ADP-ribosylation0Direct
LysM domain0Direct
TK C-terminal domain-like0Direct
S-adenosylmethionine synthetase0Direct
ValRS/IleRS/LeuRS editing domain0Direct
Proton glutamate symport protein0Direct
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain0Direct
PABC (PABP) domain0Direct
Rudiment single hybrid motif0Direct
Annexin0Direct
Class II aaRS ABD-related0Direct
Isocitrate/Isopropylmalate dehydrogenase-like0Direct
Chitinase insertion domain0Direct
Doublecortin (DC)0Direct
MIR domain0Direct
Phosphoenolpyruvate/pyruvate domain0Direct
MgtE membrane domain-like0Direct
Nop domain0Direct
Type II DNA topoisomerase0Direct
Small-conductance potassium channel0Direct
Nucleoporin domain0Direct
Molybdenum cofactor-binding domain0Direct
Surp module (SWAP domain)0Direct
PEBP-like0Direct
AN1-like Zinc finger0Direct
Translational machinery components0Direct
Ribosomal protein L10Direct
Alpha-L RNA-binding motif0Direct
Cystatin/monellin0Direct
Hect, E3 ligase catalytic domain0Direct
Galactose oxidase, central domain0Direct
PurM C-terminal domain-like0Direct
14-3-3 protein0Direct
Diaminopimelate epimerase-like0Direct
Complement control module/SCR domain0Direct
SAND domain-like0Direct
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0Direct
PGBD-like0Direct
ALDH-like0Direct
Transducin (alpha subunit), insertion domain0Direct
Sec63 N-terminal domain-like0Direct
RBP11-like subunits of RNA polymerase0Direct
Lesion bypass DNA polymerase (Y-family), little finger domain0Direct
PK beta-barrel domain-like0Direct
ARID-like0Direct
Outer arm dynein light chain 10Direct
MOSC N-terminal domain-like0Direct
eIF4e-like0Direct
CRAL/TRIO N-terminal domain0Direct
Composite domain of metallo-dependent hydrolases0Direct
GYF domain0Direct
MFPT repeat-like0Direct
Elafin-like0Direct
CO dehydrogenase molybdoprotein N-domain-like0Direct
Hypothetical protein c14orf129, hspc2100Direct
GAS2 domain-like0Direct
Acid phosphatase/Vanadium-dependent haloperoxidase0Direct
R3H domain0Direct
Rap/Ran-GAP0Direct
Citrate synthase0Direct
Ribosomal proteins S24e, L23 and L15e0Direct
Aminoacid dehydrogenase-like, N-terminal domain0Direct
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase0Direct
Zn-binding ribosomal proteins0Direct
ThrRS/AlaRS common domain0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Activating enzymes of the ubiquitin-like proteins0Direct
Ferritin-like0Direct
Blood coagulation inhibitor (disintegrin)0Direct
Fibrinogen C-terminal domain-like0Direct
Pepsin inhibitor-30Direct
TGS-like0Direct
Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase)0Direct
YWTD domain0Direct
CO dehydrogenase ISP C-domain like0Direct
YbiA-like0Direct
Pentein0Direct
Hormone receptor domain0Direct
VPS9 domain0Direct
ISP domain0Direct
PEP carboxykinase N-terminal domain0Direct
PEP carboxykinase-like0Direct
SWIB/MDM2 domain0Direct
ArfGap/RecO-like zinc finger0Direct
Single hybrid motif0Direct
Ribokinase-like0Direct
5' to 3' exonuclease, C-terminal subdomain0Direct
CBD9-like0Direct
alpha/beta knot0Direct
Restriction endonuclease-like0Direct
Cadherin-like0Direct
Ribosomal protein S100Direct
Oxysterol-binding protein-like0Direct
FF domain0Direct
Tricorn protease domain 20Direct
WGR domain-like0Direct
PurM N-terminal domain-like0Direct
PapD-like0.000302Direct
Protein kinase-like (PK-like)0.0288Inherited
Metallo-hydrolase/oxidoreductase0.2777Inherited
Nucleotide-binding domain0.4574Inherited
Quinoprotein alcohol dehydrogenase-like0.4678Inherited
FAD-linked reductases, C-terminal domain0.5116Inherited
WD40 repeat-like0.6779Inherited
PIN domain-like0.7356Inherited
CCCH zinc finger0.8182Inherited
FKBP-like0.8964Inherited
Cyclin-like1Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Ubiquitin activating enzymes (UBA)0Direct
Bacterial exopeptidase dimerisation domain0Direct
AMPK-beta glycogen binding domain-like0Direct
Lesion bypass DNA polymerase (Y-family), catalytic domain0Direct
Amylase, catalytic domain0Direct
Inositol polyphosphate 5-phosphatase (IPP5)0Direct
Cu,Zn superoxide dismutase-like0Direct
Proton glutamate symport protein0Direct
Peptidylglycine alpha-hydroxylating monooxygenase, PHM0Direct
Type II chitinase0Direct
AN1-like Zinc finger0Direct
PEP carboxykinase C-terminal domain0Direct
BC C-terminal domain-like0Direct
Branched-chain alpha-keto acid dehydrogenase Pyr module0Direct
Annexin0Direct
Chitinase insertion domain0Direct
Phosphatidylethanolamine binding protein0Direct
Chromo domain0Direct
LEM domain0Direct
Glycosyl transferases group 10Direct
Cofilin-like0Direct
UDP-glucose pyrophosphorylase0Direct
ALDH-like0Direct
Adenosine/AMP deaminase0Direct
Glycerophosphoryl diester phosphodiesterase0Direct
YWTD domain0Direct
DEATH domain, DD0Direct
DNA repair protein MutS, domain III0Direct
Acyl-CoA thioesterase0Direct
ARID domain0Direct
MOSC N-terminal domain-like0Direct
alpha-Amylases, C-terminal beta-sheet domain0Direct
Arginine methyltransferase0Direct
2Fe-2S ferredoxin domains from multidomain proteins0Direct
Gamma-glutamyltranspeptidase-like0Direct
Domain of poly(ADP-ribose) polymerase0Direct
CO dehydrogenase flavoprotein N-terminal domain-like0Direct
Poly(A) polymerase, PAP, N-terminal domain0Direct
Inositol monophosphatase/fructose-1,6-bisphosphatase-like0Direct
28-residue LRR0Direct
acyl-CoA oxidase N-terminal domains0Direct
Biotin dependent carboxylase carboxyltransferase domain0Direct
Internalin LRR domain0Direct
Arfaptin, Rac-binding fragment0Direct
Rap/Ran-GAP0Direct
RNA-polymerase beta0Direct
D-aminoacid oxidase-like0Direct
Cation efflux protein cytoplasmic domain-like0Direct
ATP-dependent protease Lon (La), catalytic domain0Direct
Acylamino-acid-releasing enzyme, C-terminal donain0Direct
Hedgehog C-terminal (Hog) autoprocessing domain0Direct
La domain0Direct
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain0Direct
CRAL/TRIO N-terminal domain0Direct
PurM N-terminal domain-like0Direct
GAS2 domain0Direct
NHL repeat0Direct
L-aminoacid/polyamine oxidase0Direct
GAPDH-like0Direct
PEP carboxykinase N-terminal domain0Direct
Sec63 C-terminal domain-like0Direct
14-3-3 protein0Direct
PurM C-terminal domain-like0Direct
Phoshoinositide 3-kinase (PI3K) helical domain0Direct
Doublecortin (DC)0Direct
Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain0Direct
VHS domain0Direct
PhzC/PhzF-like0Direct
Glycolipid transfer protein, GLTP0Direct
Pyk2-associated protein beta ARF-GAP domain0Direct
U-box0Direct
Cell cycle control phosphatase, catalytic domain0Direct
HSP90 C-terminal domain0Direct
DNA gyrase/MutL, second domain0Direct
Complement control module/SCR domain0Direct
CoA-binding domain0Direct
Hsp90 middle domain0Direct
5' to 3' exonuclease, C-terminal subdomain0Direct
Double-stranded RNA-binding domain (dsRBD)0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Matrix metalloproteases, catalytic domain0Direct
DPP6 catalytic domain-like0Direct
Oxysterol-binding protein0Direct
Fibrinogen C-terminal domain-like0Direct
RhoGDI-like0Direct
Ran binding protein zinc finger-like0Direct
Ribosomal protein L10Direct
SAND domain0Direct
Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase)0Direct
Single strand DNA-binding domain, SSB0Direct
Poly(A) polymerase, PAP, middle domain0Direct
Hormone receptor domain0Direct
Calpain large subunit, catalytic domain (domain II)0Direct
5' to 3' exonuclease catalytic domain0Direct
Regulator of chromosome condensation RCC10Direct
Elafin-like0Direct
Poly(ADP-ribose) polymerase, C-terminal domain0Direct
SWIRM domain0Direct
DEP domain0Direct
LysM domain0Direct
Class I glutamine amidotransferases (GAT)0Direct
COMT-like0Direct
HCDH C-domain-like0Direct
Inositol polyphosphate kinase (IPK)0Direct
Molybdenum cofactor-binding domain0Direct
GYF domain0Direct
beta 1,4 galactosyltransferase (b4GalT1)0Direct
MIR domain0Direct
Methionine aminopeptidase, insert domain0Direct
FF domain0Direct
Ubiquitin carboxyl-terminal hydrolase UCH-L0Direct
Citrate synthase0Direct
Epoxide hydrolase0Direct
Mitochondrial carrier0Direct
YbiA-like0Direct
Biotinyl/lipoyl-carrier proteins and domains0Direct
Hydantoinase (dihydropyrimidinase)0Direct
Blood coagulation inhibitor (disintegrin)0Direct
Transducin (alpha subunit), insertion domain0Direct
Transducin (heterotrimeric G protein), gamma chain0Direct
DNA gyrase/MutL, N-terminal domain0Direct
Sec63 N-terminal domain0Direct
IF2B-like0Direct
Ribonucleotide reductase-like0Direct
Hect, E3 ligase catalytic domain0Direct
Hydantoinase (dihydropyrimidinase), catalytic domain0Direct
Ribosomal protein L18 and S110Direct
acyl-CoA oxidase C-terminal domains0Direct
Epsilon subunit of mitochondrial F1F0-ATP synthase0Direct
Group II chaperonin (CCT, TRIC), intermediate domain0Direct
Dimeric isocitrate & isopropylmalate dehydrogenases0Direct
Hexokinase0Direct
XPF/Rad1/Mus81 nuclease0Direct
1,3-glucuronyltransferase0Direct
Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain0Direct
Anticodon-binding domain0Direct
PUA domain0Direct
Type II DNA topoisomerase0Direct
Glutaminase0Direct
Pancreatic carboxypeptidase, activation domain0Direct
First domain of FERM0Direct
beta-CASP RNA-metabolising hydrolases0Direct
Myotubularin-like phosphatases0Direct
Bactericidal permeability-increasing protein, BPI0Direct
SWIB/MDM2 domain0Direct
AlkB-like0Direct
Tryptophan synthase beta subunit-like PLP-dependent enzymes0Direct
Brix domain0Direct
Hypothetical protein c14orf129, hspc2100Direct
Ribosomal protein S100Direct
Surp module (SWAP domain)0Direct
D-aminoacid oxidase, N-terminal domain0Direct
Ribokinase-like0Direct
Cdc48 domain 2-like0Direct
BC N-terminal domain-like0Direct
NOL1/NOP2/sun0Direct
Serum paraoxonase/arylesterase 1, PON10Direct
MFPT repeat0Direct
DPP6 N-terminal domain-like0Direct
Lactate & malate dehydrogenases, C-terminal domain0Direct
Glycogenin0Direct
Protein prenyltransferases0Direct
Acireductone dioxygenase0Direct
Choline kinase0Direct
Poly(A) polymerase, PAP, C-terminal domain0Direct
UBA domain0Direct
BC ATP-binding domain-like0Direct
CO dehydrogenase ISP C-domain like0Direct
CO dehydrogenase molybdoprotein N-domain-like0Direct
Branched-chain alpha-keto acid dehydrogenase PP module0Direct
Cadherin0Direct
Thyroglobulin type-1 domain0Direct
Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain0Direct
WGR domain0Direct
SAM (sterile alpha motif) domain0Direct
HD domain0Direct
Glycerol kinase0Direct
Nop domain0Direct
Small-conductance potassium channel0Direct
CAT-like0Direct
FAD-dependent thiol oxidase0Direct
a tRNA synthase domain0Direct
Lesion bypass DNA polymerase (Y-family), little finger domain0Direct
Heat shock protein 90, HSP90, N-terminal domain0Direct
Adenain-like0Direct
ValRS/IleRS/LeuRS editing domain0Direct
Troponin I0Direct
Cytoplasmic domain of inward rectifier potassium channel0Direct
Translation initiation factor eIF4e0Direct
Anticodon-binding domain of Class II aaRS0Direct
Pepsin inhibitor-30Direct
PABC (PABP) domain0Direct
LDH N-terminal domain-like0Direct
Arylsulfatase0Direct
YihX-like0Direct
S-adenosylmethionine synthetase0Direct
Heme-dependent catalases0Direct
Aminoacid dehydrogenase-like, C-terminal domain0Direct
FtsH protease domain-like0Direct
HEAT repeat0Direct
LacY-like proton/sugar symporter0Direct
Tetraspanin0Direct
Tandem AAA-ATPase domain0.00005734Direct
MSP-like0.0007206Direct
Cyclin0.05265Inherited
WD40-repeat0.7868Inherited
CCCH zinc finger0.8Inherited
FKBP immunophilin/proline isomerase0.8808Inherited


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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
FF domain0Direct
Blood coagulation inhibitor (disintegrin)0Direct
Carbohydrate phosphatase0Direct
Fibrinogen C-terminal domain-like0Direct
Activating enzymes of the ubiquitin-like proteins0Direct
Phoshotransferase/anion transport protein0Direct
Tricorn protease domain 20Direct
Tryptophan synthase beta subunit-like PLP-dependent enzymes0Direct
14-3-3 protein0Direct
Citrate synthase0Direct
TGS-like0Direct
Transducin (heterotrimeric G protein), gamma chain0Direct
Cystatin/monellin0Direct
PreATP-grasp domain0Direct
Troponin coil-coiled subunits0Direct
TK C-terminal domain-like0Direct
Molybdenum cofactor-binding domain0Direct
Ran binding protein zinc finger-like0Direct
Oxysterol-binding protein-like0Direct
PHM/PNGase F0Direct
Nucleoporin domain0Direct
Ribosomal protein L10-like0Direct
Ribulose-phoshate binding barrel0Direct
YbiA-like0Direct
Type II DNA topoisomerase0Direct
GAS2 domain-like0Direct
RBP11-like subunits of RNA polymerase0Direct
Ribosomal protein S100Direct
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain0Direct
Cytochrome c0Direct
R3H domain0Direct
Cadherin-like0Direct
FtsH protease domain-like0Direct
CBD9-like0Direct
Hedgehog/intein (Hint) domain0Direct
MOSC N-terminal domain-like0Direct
Doublecortin (DC)0Direct
Diaminopimelate epimerase-like0Direct
Phosphoenolpyruvate/pyruvate domain0Direct
Acid phosphatase/Vanadium-dependent haloperoxidase0Direct
MIR domain0Direct
Cdc48 domain 2-like0Direct
Pepsin inhibitor-30Direct
PEP carboxykinase-like0Direct
Sec63 N-terminal domain-like0Direct
SPOC domain-like0Direct
ThrRS/AlaRS common domain0Direct
Tubby C-terminal domain-like0Direct
MgtE membrane domain-like0Direct
Carbon-nitrogen hydrolase0Direct
Complement control module/SCR domain0Direct
Ribosomal protein L10Direct
Translational machinery components0Direct
Pentein0Direct
PEBP-like0Direct
Chitinase insertion domain0Direct
LDH C-terminal domain-like0Direct
HSP90 C-terminal domain0Direct
PABC (PABP) domain0Direct
SWIB/MDM2 domain0Direct
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase0Direct
ISP domain0Direct
YWTD domain0Direct
Elafin-like0Direct
Isocitrate/Isopropylmalate dehydrogenase-like0Direct
PAP/Archaeal CCA-adding enzyme, C-terminal domain0Direct
L-aspartase-like0Direct
MFPT repeat-like0Direct
Restriction endonuclease-like0Direct
Ribosomal proteins S24e, L23 and L15e0Direct
Outer arm dynein light chain 10Direct
ArfGap/RecO-like zinc finger0Direct
AN1-like Zinc finger0Direct
DNA repair protein MutS, domain III0Direct
Small-conductance potassium channel0Direct
LysM domain0Direct
CRAL/TRIO N-terminal domain0Direct
Ferritin-like0Direct
Bacterial exopeptidase dimerisation domain0Direct
VPS9 domain0Direct
Domain of poly(ADP-ribose) polymerase0Direct
Epsilon subunit of mitochondrial F1F0-ATP synthase0Direct
Radical SAM enzymes0Direct
Lesion bypass DNA polymerase (Y-family), little finger domain0Direct
Transducin (alpha subunit), insertion domain0Direct
Ribokinase-like0Direct
Nop domain0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
CO dehydrogenase molybdoprotein N-domain-like0Direct
PurM C-terminal domain-like0Direct
Cu,Zn superoxide dismutase-like0Direct
Mitochondrial carrier0Direct
Hect, E3 ligase catalytic domain0Direct
Annexin0Direct
PGBD-like0Direct
Zn-binding ribosomal proteins0Direct
Aminoacid dehydrogenase-like, N-terminal domain0Direct
Thiamin diphosphate-binding fold (THDP-binding)0Direct
LEM domain0Direct
5' to 3' exonuclease, C-terminal subdomain0Direct
Thyroglobulin type-1 domain0Direct
Cation efflux protein cytoplasmic domain-like0Direct
Terpenoid cyclases/Protein prenyltransferases0Direct
ValRS/IleRS/LeuRS editing domain0Direct
alpha/beta knot0Direct
Glycolipid transfer protein, GLTP0Direct
ALDH-like0Direct
WGR domain-like0Direct
PEP carboxykinase N-terminal domain0Direct
Heme-dependent catalase-like0Direct
eIF4e-like0Direct
Rudiment single hybrid motif0Direct
Surp module (SWAP domain)0Direct
Class II aaRS ABD-related0Direct
Galactose oxidase, central domain0Direct
PurM N-terminal domain-like0Direct
Rap/Ran-GAP0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
ADP-ribosylation0Direct
Creatinase/prolidase N-terminal domain0Direct
S-adenosylmethionine synthetase0Direct
Alpha-L RNA-binding motif0Direct
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0Direct
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain0Direct
Composite domain of metallo-dependent hydrolases0Direct
Hormone receptor domain0Direct
Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase)0Direct
Hypothetical protein c14orf129, hspc2100Direct
GYF domain0Direct
Single hybrid motif0Direct
Proton glutamate symport protein0Direct
CO dehydrogenase ISP C-domain like0Direct
SAND domain-like0Direct
PK beta-barrel domain-like0Direct
ARID-like0Direct
PapD-like0.0002477Direct
Protein kinase-like (PK-like)0.02516Inherited
Metallo-hydrolase/oxidoreductase0.2585Inherited
Nucleotide-binding domain0.4345Inherited
Quinoprotein alcohol dehydrogenase-like0.4451Inherited
FAD-linked reductases, C-terminal domain0.4892Inherited
WD40 repeat-like0.6566Inherited
PIN domain-like0.7161Inherited
CCCH zinc finger0.8013Inherited
FKBP-like0.8831Inherited
Cyclin-like1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
55486,57552
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 57552 - Blood coagulation inhibitor (disintegrin)
  • 0Direct
    47473,103506
  • 47473 - EF-hand
  • 103506 - Mitochondrial carrier
  • 0Direct
    51971,54373
  • 51971 - Nucleotide-binding domain
  • 54373 - FAD-linked reductases, C-terminal domain
  • 0Direct
    54585,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    81698,81698
  • 81698 - FF domain
  • 81698 - FF domain
  • 0Direct
    52047,48371
  • 52047 - RNI-like
  • 48371 - ARM repeat
  • 0Direct
    51905,56425
  • 51905 - FAD/NAD(P)-binding domain
  • 56425 - Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain
  • 0Direct
    51338,51556
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 51556 - Metallo-dependent hydrolases
  • 0Direct
    81631,55003
  • 81631 - PAP/OAS1 substrate-binding domain
  • 55003 - PAP/Archaeal CCA-adding enzyme, C-terminal domain
  • 0Direct
    51556,51338
  • 51556 - Metallo-dependent hydrolases
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 0Direct
    55326,56042
  • 55326 - PurM N-terminal domain-like
  • 56042 - PurM C-terminal domain-like
  • 0Direct
    54160,54160
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 0Direct
    47090,55486
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0Direct
    49742,49742
  • 49742 - PHM/PNGase F
  • 49742 - PHM/PNGase F
  • 0Direct
    55729,55729
  • 55729 - Acyl-CoA N-acyltransferases (Nat)
  • 55729 - Acyl-CoA N-acyltransferases (Nat)
  • 0Direct
    50692,54585
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 0Direct
    55486,50923
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 0Direct
    50249,50249
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 0Direct
    52540,90123
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 90123 - ABC transporter transmembrane region
  • 0Direct
    57196,63825
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 0Direct
    51045,51045
  • 51045 - WW domain
  • 51045 - WW domain
  • 0Direct
    47769,47769
  • 47769 - SAM/Pointed domain
  • 47769 - SAM/Pointed domain
  • 0Direct
    57850,117839
  • 57850 - RING/U-box
  • 117839 - WWE domain
  • 0Direct
    52518,52518
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 0Direct
    57903,82199
  • 57903 - FYVE/PHD zinc finger
  • 82199 - SET domain
  • 0Direct
    52540,140990
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 140990 - FtsH protease domain-like
  • 0Direct
    47587,56399
  • 47587 - Domain of poly(ADP-ribose) polymerase
  • 56399 - ADP-ribosylation
  • 0Direct
    57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0Direct
    47473,51695
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 0Direct
    55394,55394
  • 55394 - Bactericidal permeability-increasing protein, BPI
  • 55394 - Bactericidal permeability-increasing protein, BPI
  • 0Direct
    56672,100879
  • 56672 - DNA/RNA polymerases
  • 100879 - Lesion bypass DNA polymerase (Y-family), little finger domain
  • 0Direct
    81324,53850
  • 81324 - Voltage-gated potassium channels
  • 53850 - Periplasmic binding protein-like II
  • 0Direct
    52540,47917
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase
  • 0Direct
    50677,52374
  • 50677 - ValRS/IleRS/LeuRS editing domain
  • 52374 - Nucleotidylyl transferase
  • 0Direct
    50249,55681
  • 50249 - Nucleic acid-binding proteins
  • 55681 - Class II aaRS and biotin synthetases
  • 0Direct
    49562,48371
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 0Direct
    101690,53098
  • 101690 - PAZ domain
  • 53098 - Ribonuclease H-like
  • 0Direct
    48403,52151
  • 48403 - Ankyrin repeat
  • 52151 - FabD/lysophospholipase-like
  • 0Direct
    52518,52922
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 52922 - TK C-terminal domain-like
  • 0Direct
    54001,49758
  • 54001 - Cysteine proteinases
  • 49758 - Calpain large subunit, middle domain (domain III)
  • 0Direct
    144232,82199
  • 144232 - HIT/MYND zinc finger-like
  • 82199 - SET domain
  • 0Direct
    161093,161093
  • 161093 - MgtE membrane domain-like
  • 161093 - MgtE membrane domain-like
  • 0Direct
    54897,53187
  • 54897 - Protease propeptides/inhibitors
  • 53187 - Zn-dependent exopeptidases
  • 0Direct
    55920,46785
  • 55920 - Creatinase/aminopeptidase
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    57196,49899
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    56059,51246
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 51246 - Rudiment single hybrid motif
  • 0Direct
    68923,53795
  • 68923 - PEP carboxykinase N-terminal domain
  • 53795 - PEP carboxykinase-like
  • 0Direct
    46938,52087
  • 46938 - CRAL/TRIO N-terminal domain
  • 52087 - CRAL/TRIO domain
  • 0Direct
    48334,52540
  • 48334 - DNA repair protein MutS, domain III
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    56112,48371
  • 56112 - Protein kinase-like (PK-like)
  • 48371 - ARM repeat
  • 0Direct
    81324,81327
  • 81324 - Voltage-gated potassium channels
  • 81327 - Small-conductance potassium channel
  • 0Direct
    57362,57362
  • 57362 - BPTI-like
  • 57362 - BPTI-like
  • 0Direct
    51445,54556
  • 51445 - (Trans)glycosidases
  • 54556 - Chitinase insertion domain
  • 0Direct
    47576,47576
  • 47576 - Calponin-homology domain, CH-domain
  • 47576 - Calponin-homology domain, CH-domain
  • 0Direct
    54495,46934
  • 54495 - UBC-like
  • 46934 - UBA-like
  • 0Direct
    141673,50800
  • 141673 - MOSC N-terminal domain-like
  • 50800 - PK beta-barrel domain-like
  • 0Direct
    55973,55973
  • 55973 - S-adenosylmethionine synthetase
  • 55973 - S-adenosylmethionine synthetase
  • 0Direct
    53187,55031
  • 53187 - Zn-dependent exopeptidases
  • 55031 - Bacterial exopeptidase dimerisation domain
  • 0Direct
    55681,52954
  • 55681 - Class II aaRS and biotin synthetases
  • 52954 - Class II aaRS ABD-related
  • 0Direct
    51735,50129
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 50129 - GroES-like
  • 0Direct
    53474,53474
  • 53474 - alpha/beta-Hydrolases
  • 53474 - alpha/beta-Hydrolases
  • 0Direct
    47203,47203
  • 47203 - Acyl-CoA dehydrogenase C-terminal domain-like
  • 47203 - Acyl-CoA dehydrogenase C-terminal domain-like
  • 0Direct
    64356,49447
  • 64356 - SNARE-like
  • 49447 - Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor
  • 0Direct
    54768,54768
  • 54768 - dsRNA-binding domain-like
  • 54768 - dsRNA-binding domain-like
  • 0Direct
    50729,47473
  • 50729 - PH domain-like
  • 47473 - EF-hand
  • 0Direct
    46785,46785
  • 46785 - "Winged helix" DNA-binding domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    54292,47741
  • 54292 - 2Fe-2S ferredoxin-like
  • 47741 - CO dehydrogenase ISP C-domain like
  • 0Direct
    47741,56176
  • 47741 - CO dehydrogenase ISP C-domain like
  • 56176 - FAD-binding/transporter-associated domain-like
  • 0Direct
    57756,50630
  • 57756 - Retrovirus zinc finger-like domains
  • 50630 - Acid proteases
  • 0Direct
    81383,52047
  • 81383 - F-box domain
  • 52047 - RNI-like
  • 0Direct
    57903,51197
  • 57903 - FYVE/PHD zinc finger
  • 51197 - Clavaminate synthase-like
  • 0Direct
    54534,54534
  • 54534 - FKBP-like
  • 54534 - FKBP-like
  • 0Direct
    56601,48403
  • 56601 - beta-lactamase/transpeptidase-like
  • 48403 - Ankyrin repeat
  • 0Direct
    52540,46785
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    52047,52047
  • 52047 - RNI-like
  • 52047 - RNI-like
  • 0Direct
    81324,81296
  • 81324 - Voltage-gated potassium channels
  • 81296 - E set domains
  • 0Direct
    57863,48403
  • 57863 - ArfGap/RecO-like zinc finger
  • 48403 - Ankyrin repeat
  • 0Direct
    55874,54211
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0Direct
    51445,51445
  • 51445 - (Trans)glycosidases
  • 51445 - (Trans)glycosidases
  • 0Direct
    161111,160240
  • 161111 - Cation efflux protein transmembrane domain-like
  • 160240 - Cation efflux protein cytoplasmic domain-like
  • 0Direct
    49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0Direct
    47895,52540
  • 47895 - Transducin (alpha subunit), insertion domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    52540,81271
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 81271 - TGS-like
  • 0Direct
    54665,56003
  • 54665 - CO dehydrogenase molybdoprotein N-domain-like
  • 56003 - Molybdenum cofactor-binding domain
  • 0Direct
    48179,48179
  • 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
  • 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
  • 0Direct
    52440,56059
  • 52440 - PreATP-grasp domain
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 0Direct
    51735,55347
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 55347 - Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain
  • 0Direct
    51735,56327
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 56327 - LDH C-terminal domain-like
  • 0Direct
    48425,50729
  • 48425 - Sec7 domain
  • 50729 - PH domain-like
  • 0Direct
    141739,141739
  • 141739 - MFPT repeat-like
  • 141739 - MFPT repeat-like
  • 0Direct
    81383,50978
  • 81383 - F-box domain
  • 50978 - WD40 repeat-like
  • 0Direct
    54160,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    50978,50998
  • 50978 - WD40 repeat-like
  • 50998 - Quinoprotein alcohol dehydrogenase-like
  • 0Direct
    103473,103473
  • 103473 - MFS general substrate transporter
  • 103473 - MFS general substrate transporter
  • 0Direct
    55550,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.0006507Direct
    52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.0006595Direct
    47954,47954
  • 47954 - Cyclin-like
  • 47954 - Cyclin-like
  • 1Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    52440,56059,51246
  • 52440 - PreATP-grasp domain
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 51246 - Rudiment single hybrid motif
  • 0Direct
    50044,50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0Direct
    49785,49785,49785
  • 49785 - Galactose-binding domain-like
  • 49785 - Galactose-binding domain-like
  • 49785 - Galactose-binding domain-like
  • 0Direct
    50692,54585,52540
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    46938,52087,101576
  • 46938 - CRAL/TRIO N-terminal domain
  • 52087 - CRAL/TRIO domain
  • 101576 - Supernatant protein factor (SPF), C-terminal domain
  • 0Direct
    54160,54160,52540
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    57567,57567,57567
  • 57567 - Serine protease inhibitors
  • 57567 - Serine protease inhibitors
  • 57567 - Serine protease inhibitors
  • 0Direct
    50729,47473,51695
  • 50729 - PH domain-like
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 0Direct
    52540,90123,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    47090,55486,50923
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 0Direct
    63411,63411,63411
  • 63411 - LuxS/MPP-like metallohydrolase
  • 63411 - LuxS/MPP-like metallohydrolase
  • 63411 - LuxS/MPP-like metallohydrolase
  • 0Direct
    55973,55973,55973
  • 55973 - S-adenosylmethionine synthetase
  • 55973 - S-adenosylmethionine synthetase
  • 55973 - S-adenosylmethionine synthetase
  • 0Direct
    50044,55550,56112
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    50249,50249,50249
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 0Direct
    50129,51735,50129
  • 50129 - GroES-like
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 50129 - GroES-like
  • 0Direct
    54292,47741,56176
  • 54292 - 2Fe-2S ferredoxin-like
  • 47741 - CO dehydrogenase ISP C-domain like
  • 56176 - FAD-binding/transporter-associated domain-like
  • 0Direct
    57535,57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0Direct
    49313,49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0Direct
    56645,47203,47203
  • 56645 - Acyl-CoA dehydrogenase NM domain-like
  • 47203 - Acyl-CoA dehydrogenase C-terminal domain-like
  • 47203 - Acyl-CoA dehydrogenase C-terminal domain-like
  • 0Direct
    49562,48371,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    57362,57362,57362
  • 57362 - BPTI-like
  • 57362 - BPTI-like
  • 57362 - BPTI-like
  • 0Direct
    51735,48179,48179
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
  • 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
  • 0Direct
    52540,52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    54160,52540,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    48726,49265,48726
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 48726 - Immunoglobulin
  • 0Direct
    54585,52540,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    90123,52540,90123
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 90123 - ABC transporter transmembrane region
  • 0Direct
    81301,81631,55003
  • 81301 - Nucleotidyltransferase
  • 81631 - PAP/OAS1 substrate-binding domain
  • 55003 - PAP/Archaeal CCA-adding enzyme, C-terminal domain
  • 0Direct
    56436,49854,49854
  • 56436 - C-type lectin-like
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 0Direct


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