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Worm Phenotype (WP): metabolic pathway variant

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Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)

Shortest distance to current term (+ for parents, - for children) WP term [WP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + 5:   Variant [WBPhenotype:0000886] <5>
+ + + + 4:   physiology variant [WBPhenotype:0000519] <7>(494|573) (495|248|68)
+ + + 3:   organism physiology variant [WBPhenotype:0000576] <10>(354|423) (357|200|60)
+ + 2:   organism homeostasis metabolism variant [WBPhenotype:0000577] <17>(343|412) (348|198|59)
+ 1:   organism metabolism processing variant [WBPhenotype:0000027] <25>(167|178) (172|81|24)
0:   metabolic pathway variant [WBPhenotype:0000463] <8>(34|27) (34|16|8)
- 1:   protein metabolism variant [WBPhenotype:0001644] <10>(28|24) (28|15|8)
- 1:   DNA metabolism variant [WBPhenotype:0000732] <7>(1|0) (1|0|0)
- 1:   RNA metabolism variant [WBPhenotype:0001827] <6>(1|1) (1|1|0)
- 1:   biosynthesis variant [WBPhenotype:0001696] <5>(0|0) (0|0|0)
- 1:   amino acid metabolism variant [WBPhenotype:0002255](0|0) (0|0|0)
- 1:   metabolite content decreased [WBPhenotype:0002270](0|0) (0|0|0)
- 1:   metabolite content increased [WBPhenotype:0002357](0|0) (0|0|0)
- 1:   second messenger mediated signaling variant [WBPhenotype:0001841](3|2) (3|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
SET domain0.0000001947Direct
Protein kinase-like (PK-like)0.000000336Direct
ADC-like0.0000298Direct
Integrin domains0.0000298Direct
Cdc48 domain 2-like0.0000298Direct
Calpain large subunit, middle domain (domain III)0.00005341Direct
Lipovitellin-phosvitin complex; beta-sheet shell regions0.0003141Direct
Lipovitellin-phosvitin complex, superhelical domain0.0003141Direct
C2 domain (Calcium/lipid-binding domain, CaLB)0.000327Direct
Fibronectin type III0.0003976Direct
PH domain-like0.0008062Direct
GroEL-intermediate domain like0.00241Inherited
GroEL equatorial domain-like0.00241Inherited
Voltage-gated potassium channels0.002911Inherited
Spectrin repeat0.004247Inherited
cAMP-binding domain-like0.004247Inherited
GroEL apical domain-like0.004954Inherited
F1F0 ATP synthase subunit C0.007099Inherited
Quinoprotein alcohol dehydrogenase-like0.0171Inherited
DNA/RNA polymerases0.01717Inherited
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.01717Inherited
FYVE/PHD zinc finger0.01997Inherited
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.03505Inherited
CCCH zinc finger0.03505Inherited
Translation proteins0.03505Inherited
Immunoglobulin0.03522Inherited
SNARE-like0.06172Inherited
Clavaminate synthase-like0.08731Inherited
Cyclin-like0.1099Inherited
Sm-like ribonucleoproteins0.1908Inherited
Transducin (alpha subunit), insertion domain0.2336Inherited
Nucleotide cyclase0.2506Inherited
Periplasmic binding protein-like I0.2944Inherited
Homeodomain-like0.832Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Integrin domains0Direct
Histone lysine methyltransferases0.00003431Direct
Cdc48 N-terminal domain-like0.00005269Direct
Cdc48 domain 2-like0.00005269Direct
Calpain large subunit, middle domain (domain III)0.00005371Direct
Protein kinases, catalytic subunit0.00006673Direct
Phoshoinositide 3-kinase (PI3K), catalytic domain0.0002261Direct
Lipovitellin-phosvitin complex; beta-sheet shell regions0.0003047Direct
Lipovitellin-phosvitin complex, superhelical domain0.0003047Direct
Calpain large subunit, catalytic domain (domain II)0.0004257Direct
Pleckstrin-homology domain (PH domain)0.0005543Direct
Spectrin repeat0.001473Inherited
Group II chaperonin (CCT, TRIC), intermediate domain0.001694Inherited
I set domains0.002641Inherited
F1F0 ATP synthase subunit C0.006842Inherited
Proteasome subunits0.008354Inherited
Group II chaperonin (CCT, TRIC), ATPase domain0.009267Inherited
Elongation factors0.009287Inherited
Voltage-gated potassium channels0.01637Inherited
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.0168Inherited
Group II chaperonin (CCT, TRIC), apical domain0.01728Inherited
LIM domain0.03253Inherited
Clathrin adaptor core protein0.03253Inherited
CCCH zinc finger0.03782Inherited
PHD domain0.04419Inherited
Transducin (alpha subunit), insertion domain0.2392Inherited
Adenylyl and guanylyl cyclase catalytic domain0.3648Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
SET domain0.0000001552Direct
Protein kinase-like (PK-like)0.0000002683Direct
Cdc48 domain 2-like0.00002418Direct
ADC-like0.00002418Direct
Integrin domains0.00002418Direct
Calpain large subunit, middle domain (domain III)0.00004343Direct
Lipovitellin-phosvitin complex, superhelical domain0.0002574Direct
Lipovitellin-phosvitin complex; beta-sheet shell regions0.0002574Direct
C2 domain (Calcium/lipid-binding domain, CaLB)0.000268Direct
Fibronectin type III0.0003262Direct
PH domain-like0.0006656Direct
GroEL equatorial domain-like0.002016Inherited
GroEL-intermediate domain like0.002016Inherited
Voltage-gated potassium channels0.00244Inherited
Spectrin repeat0.003581Inherited
cAMP-binding domain-like0.003581Inherited
GroEL apical domain-like0.004184Inherited
F1F0 ATP synthase subunit C0.006022Inherited
Quinoprotein alcohol dehydrogenase-like0.01473Inherited
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.01479Inherited
DNA/RNA polymerases0.01479Inherited
FYVE/PHD zinc finger0.01727Inherited
CCCH zinc finger0.03071Inherited
Translation proteins0.03071Inherited
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.03071Inherited
Immunoglobulin0.03086Inherited
SNARE-like0.0548Inherited
Clavaminate synthase-like0.0783Inherited
Cyclin-like0.09922Inherited
Sm-like ribonucleoproteins0.1748Inherited
Transducin (alpha subunit), insertion domain0.216Inherited
Nucleotide cyclase0.2324Inherited
Periplasmic binding protein-like I0.275Inherited
Homeodomain-like0.8152Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
50692,54585
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 0Direct
    54585,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    54001,49758
  • 54001 - Cysteine proteinases
  • 49758 - Calpain large subunit, middle domain (domain III)
  • 0.00004343Direct
    48431,56968
  • 48431 - Lipovitellin-phosvitin complex, superhelical domain
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 0.0002574Direct
    56968,48431
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 48431 - Lipovitellin-phosvitin complex, superhelical domain
  • 0.0002574Direct
    81333,81333
  • 81333 - F1F0 ATP synthase subunit C
  • 81333 - F1F0 ATP synthase subunit C
  • 0.001496Inherited
    48592,54849
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 0.002016Inherited
    54849,52029
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.002016Inherited
    48065,50729
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0.003581Inherited
    48726,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.003816Inherited
    90229,90229
  • 90229 - CCCH zinc finger
  • 90229 - CCCH zinc finger
  • 0.004184Inherited
    46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.006022Inherited
    52540,50447
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 0.007663Inherited
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.03073Inherited
    47954,47954
  • 47954 - Cyclin-like
  • 47954 - Cyclin-like
  • 0.03788Inherited
    47895,52540
  • 47895 - Transducin (alpha subunit), insertion domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.216Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    50692,54585,52540
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    54585,52540,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    56968,48431,56968
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 48431 - Lipovitellin-phosvitin complex, superhelical domain
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 0.0002574Direct
    48592,54849,52029
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.002016Inherited
    46966,46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.006022Inherited
    48726,48726,49265
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.006022Inherited
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.02023Inherited
    57716,57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.04798Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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