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Worm Phenotype (WP): organ system development variant

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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)

Shortest distance to current term (+ for parents, - for children) WP term [WP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   Variant [WBPhenotype:0000886] <2>
+ + 2:   physiology variant [WBPhenotype:0000519] <14>(510|587) (510|248|69)
+ 1:   development variant [WBPhenotype:0000518] <6>(508|585) (508|248|69)
0:   organ system development variant [WBPhenotype:0000530] <10>(79|72) (80|33|13)
- 1:   reproductive system development variant [WBPhenotype:0000624] <10>(48|41) (49|22|9)
- 1:   nervous system development variant [WBPhenotype:0000623] <7>(9|6) (10|2|1)
- 1:   alimentary system development variant [WBPhenotype:0000617] <6>(11|9) (11|5|3)
- 1:   muscle system development variant [WBPhenotype:0000622] <5>(7|5) (7|2|1)
- 1:   coelomic system development variant [WBPhenotype:0000618] <3>(1|2) (1|0|0)
- 1:   epithelial system development variant [WBPhenotype:0000619] <3>(14|13) (14|5|1)
- 1:   ectopic organ [WBPhenotype:0002498] <2>(0|0) (0|0|0)
- 1:   excretory secretory system development variant [WBPhenotype:0000620] <2>(6|7) (6|1|0)
- 1:   organ senescence variant [WBPhenotype:0001740](0|0) (0|0|0)
- 1:   tube morphogenesis variant [WBPhenotype:0001848](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
ArfGap/RecO-like zinc finger0Direct
14-3-3 protein0Direct
Integrin alpha N-terminal domain0Direct
Frizzled cysteine-rich domain0Direct
ARM repeat0.00000000000009847Direct
"Winged helix" DNA-binding domain0.000000000001949Direct
P-loop containing nucleoside triphosphate hydrolases0.000000000002488Direct
RNA-binding domain, RBD0.00000000003918Direct
Immunoglobulin0.00000000006247Direct
EGF/Laminin0.000000003776Direct
Homeodomain-like0.000000005595Direct
PH domain-like0.00000001088Direct
Bromodomain0.00000003241Direct
Fibronectin type III0.0000004141Direct
WD40 repeat-like0.0000005207Direct
Sm-like ribonucleoproteins0.0000008538Direct
Growth factor receptor domain0.000003406Direct
PYP-like sensor domain (PAS domain)0.00001654Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.00001767Direct
HLH, helix-loop-helix DNA-binding domain0.00003409Direct
Tubulin C-terminal domain-like0.00004176Direct
FYVE/PHD zinc finger0.0001081Direct
Sec7 domain0.0001261Direct
Tubulin nucleotide-binding domain-like0.0001792Direct
Band 7/SPFH domain0.0001972Direct
Protein kinase-like (PK-like)0.000269Direct
Activating enzymes of the ubiquitin-like proteins0.0003514Direct
SNARE-like0.0003942Direct
Intermediate filament protein, coiled coil region0.0004221Direct
HMG-box0.0005614Direct
Plexin repeat0.0006268Direct
Sema domain0.0006268Direct
KA1-like0.0006268Direct
Sec1/munc18-like (SM) proteins0.0006268Direct
ADC-like0.0008749Direct
Cdc48 domain 2-like0.0008749Direct
Integrin domains0.0008749Direct
E2F-DP heterodimerization region0.0008749Direct
Myosin rod fragments0.000893Direct
Cullin repeat-like0.000893Direct
GroEL equatorial domain-like0.000893Direct
GroEL-intermediate domain like0.000893Direct
beta-beta-alpha zinc fingers0.0009398Direct
Cullin homology domain0.001838Inherited
GroEL apical domain-like0.001893Inherited
Calponin-homology domain, CH-domain0.002016Inherited
Lamin A/C globular tail domain0.003557Inherited
F1F0 ATP synthase subunit C0.003586Inherited
Sec63 N-terminal domain-like0.003586Inherited
CCCH zinc finger0.004122Inherited
Cyclin-like0.005527Inherited
PDZ domain-like0.006763Inherited
Arginase/deacetylase0.007887Inherited
SMAD MH1 domain0.008953Inherited
Histone-fold0.009787Inherited
Nucleic acid-binding proteins0.009798Inherited
TPR-like0.01267Inherited
Chromo domain-like0.02505Inherited
Troponin coil-coiled subunits0.02991Inherited
TSP-1 type 1 repeat0.03443Inherited
Concanavalin A-like lectins/glucanases0.0396Inherited
BAR/IMD domain-like0.04219Inherited
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.05117Inherited
HIT/MYND zinc finger-like0.05818Inherited
vWA-like0.08151Inherited
Ankyrin repeat0.1058Inherited
Ubiquitin-like0.1075Inherited
SMAD/FHA domain0.1334Inherited
Cystine-knot cytokines0.1416Inherited
SET domain0.147Inherited
Cadherin-like0.2126Inherited
ABC transporter transmembrane region0.3517Inherited
Voltage-gated potassium channels0.4157Inherited
Acyl-CoA N-acyltransferases (Nat)0.4307Inherited
Nucleotide-diphospho-sugar transferases0.7513Inherited
F-box domain1Inherited
NAD(P)-binding Rossmann-fold domains1Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Integrin domains0Direct
Mo25 protein0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
POU-specific domain0Direct
14-3-3 protein0Direct
Pyk2-associated protein beta ARF-GAP domain0Direct
Laminin-type module0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Frizzled cysteine-rich domain0Direct
Canonical RBD0.000000001344Direct
Homeodomain0.00000003699Direct
Bromodomain0.000000181Direct
Sm motif of small nuclear ribonucleoproteins, SNRNP0.000004379Direct
Pleckstrin-homology domain (PH domain)0.000004697Direct
Fibronectin type III0.000005418Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.00003741Direct
I set domains0.00007852Direct
Tubulin, C-terminal domain0.0001481Direct
Erythroid transcription factor GATA-10.0001519Direct
Band 7/SPFH domain0.0001519Direct
Sema domain0.0002246Direct
Sec7 domain0.0002246Direct
HLH, helix-loop-helix DNA-binding domain0.0002277Direct
PDZ domain0.0003696Direct
Pumilio repeat0.0004216Direct
ets domain0.0004216Direct
WD40-repeat0.0004898Direct
Tubulin, GTPase domain0.000534Direct
Intermediate filament protein, coiled coil region0.0009677Direct
Proteasome subunits0.001018Inherited
Cullin repeat0.001101Inherited
SCF ubiquitin ligase complex WHB domain0.001101Inherited
DNA replication initiator (cdc21/cdc54) N-terminal domain0.001101Inherited
Plexin repeat0.001101Inherited
Cell cycle transcription factor e2f-dp0.001327Inherited
DEATH domain, DD0.001327Inherited
Cdc48 N-terminal domain-like0.001327Inherited
Cdc48 domain 2-like0.001327Inherited
PHD domain0.001341Inherited
HMG-box0.001601Inherited
Cyclin0.001601Inherited
Myosin rod fragments0.00178Inherited
Protein kinases, catalytic subunit0.002894Inherited
G proteins0.003061Inherited
Clathrin coat assembly domain0.003193Inherited
Clathrin adaptor core protein0.003193Inherited
Cullin homology domain0.003193Inherited
Paired domain0.003724Inherited
Histone lysine methyltransferases0.004908Inherited
Transforming growth factor (TGF)-beta0.005423Inherited
F1F0 ATP synthase subunit C0.005423Inherited
DEP domain0.005423Inherited
Calponin-homology domain, CH-domain0.006461Inherited
Laminin G-like module0.006849Inherited
Group II chaperonin (CCT, TRIC), ATPase domain0.007088Inherited
Histone deacetylase, HDAC0.007088Inherited
CCCH zinc finger0.01157Inherited
Group II chaperonin (CCT, TRIC), apical domain0.01337Inherited
SMAD MH1 domain0.01347Inherited
RecA protein-like (ATPase-domain)0.01347Inherited
N-acetyl transferase, NAT0.02025Inherited
Myb/SANT domain0.0445Inherited
SMAD domain0.0445Inherited
Armadillo repeat0.05076Inherited
Nucleosome core histones0.06319Inherited
Lamin A/C globular tail domain0.06776Inherited
TBP-associated factors, TAFs0.1651Inherited
Cadherin0.1651Inherited
Chromo domain0.2051Inherited
Ankyrin repeat0.2604Inherited
ABC transporter transmembrane region0.3903Inherited
ABC transporter ATPase domain-like0.6412Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
14-3-3 protein0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Frizzled cysteine-rich domain0Direct
ArfGap/RecO-like zinc finger0Direct
Integrin alpha N-terminal domain0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
ARM repeat0.00000000000007729Direct
"Winged helix" DNA-binding domain0.000000000001535Direct
P-loop containing nucleoside triphosphate hydrolases0.00000000000196Direct
RNA-binding domain, RBD0.00000000003094Direct
Immunoglobulin0.00000000004937Direct
EGF/Laminin0.000000003004Direct
Homeodomain-like0.000000004455Direct
PH domain-like0.00000000867Direct
Bromodomain0.00000002589Direct
Fibronectin type III0.0000003333Direct
WD40 repeat-like0.0000004194Direct
Sm-like ribonucleoproteins0.0000006891Direct
Growth factor receptor domain0.000002764Direct
PYP-like sensor domain (PAS domain)0.00001347Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.0000144Direct
HLH, helix-loop-helix DNA-binding domain0.00002782Direct
Tubulin C-terminal domain-like0.00003411Direct
FYVE/PHD zinc finger0.00008852Direct
Sec7 domain0.0001033Direct
Tubulin nucleotide-binding domain-like0.000147Direct
Band 7/SPFH domain0.0001619Direct
Protein kinase-like (PK-like)0.0002213Direct
Activating enzymes of the ubiquitin-like proteins0.0002895Direct
SNARE-like0.0003251Direct
Intermediate filament protein, coiled coil region0.0003484Direct
HMG-box0.0004648Direct
KA1-like0.0005191Direct
Sema domain0.0005191Direct
Plexin repeat0.0005191Direct
Sec1/munc18-like (SM) proteins0.0005191Direct
Cdc48 domain 2-like0.0007274Direct
Integrin domains0.0007274Direct
ADC-like0.0007274Direct
E2F-DP heterodimerization region0.0007274Direct
GroEL equatorial domain-like0.0007425Direct
Myosin rod fragments0.0007425Direct
Cullin repeat-like0.0007425Direct
GroEL-intermediate domain like0.0007425Direct
beta-beta-alpha zinc fingers0.0007818Direct
Cullin homology domain0.001539Inherited
GroEL apical domain-like0.001586Inherited
Calponin-homology domain, CH-domain0.00169Inherited
Lamin A/C globular tail domain0.003008Inherited
Sec63 N-terminal domain-like0.003033Inherited
F1F0 ATP synthase subunit C0.003033Inherited
CCCH zinc finger0.003491Inherited
Cyclin-like0.0047Inherited
PDZ domain-like0.005768Inherited
Arginase/deacetylase0.006745Inherited
beta and beta-prime subunits of DNA dependent RNA-polymerase0.007679Inherited
SMAD MH1 domain0.007679Inherited
Histone-fold0.008412Inherited
Nucleic acid-binding proteins0.008422Inherited
TPR-like0.01093Inherited
Chromo domain-like0.02189Inherited
Troponin coil-coiled subunits0.02624Inherited
TSP-1 type 1 repeat0.03029Inherited
Concanavalin A-like lectins/glucanases0.0349Inherited
BAR/IMD domain-like0.03723Inherited
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.04538Inherited
HIT/MYND zinc finger-like0.05175Inherited
vWA-like0.07317Inherited
Ankyrin repeat0.09567Inherited
Ubiquitin-like0.09724Inherited
SMAD/FHA domain0.1214Inherited
Cystine-knot cytokines0.1291Inherited
SET domain0.1341Inherited
Cadherin-like0.1963Inherited
ABC transporter transmembrane region0.3316Inherited
Voltage-gated potassium channels0.3949Inherited
Acyl-CoA N-acyltransferases (Nat)0.4099Inherited
Nucleotide-diphospho-sugar transferases0.7316Inherited
F-box domain1Inherited
NAD(P)-binding Rossmann-fold domains1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
50692,54585
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 0Direct
    57863,48403
  • 57863 - ArfGap/RecO-like zinc finger
  • 48403 - Ankyrin repeat
  • 0Direct
    52540,47917
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase
  • 0Direct
    54585,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    46785,144074
  • 46785 - "Winged helix" DNA-binding domain
  • 144074 - E2F-DP heterodimerization region
  • 0Direct
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.0000000003563Direct
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.0000000354Direct
    54928,54928
  • 54928 - RNA-binding domain, RBD
  • 54928 - RNA-binding domain, RBD
  • 0.0000245Direct
    48726,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.00003411Direct
    52490,55307
  • 52490 - Tubulin nucleotide-binding domain-like
  • 55307 - Tubulin C-terminal domain-like
  • 0.000147Direct
    48371,48371
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 0.000147Direct
    49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.0002895Direct
    47954,47954
  • 47954 - Cyclin-like
  • 47954 - Cyclin-like
  • 0.0003251Direct
    75632,46785
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0.0005191Direct
    74788,75632
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 0.0005191Direct
    101912,103575
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 0.0007274Direct
    64356,49447
  • 64356 - SNARE-like
  • 49447 - Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor
  • 0.0007274Direct
    81333,81333
  • 81333 - F1F0 ATP synthase subunit C
  • 81333 - F1F0 ATP synthase subunit C
  • 0.0007274Direct
    55550,50044
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0.0007274Direct
    49265,48726
  • 49265 - Fibronectin type III
  • 48726 - Immunoglobulin
  • 0.0007274Direct
    48592,54849
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 0.0007425Direct
    54849,52029
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.0007425Direct
    48452,48452
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 0.0008408Direct
    82895,82895
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 0.001586Inherited
    57903,57903
  • 57903 - FYVE/PHD zinc finger
  • 57903 - FYVE/PHD zinc finger
  • 0.003033Inherited
    52113,52113
  • 52113 - BRCT domain
  • 52113 - BRCT domain
  • 0.007679Inherited
    48065,50729
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0.008271Inherited
    54160,54160
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 0.01522Inherited
    64593,74853
  • 64593 - Intermediate filament protein, coiled coil region
  • 74853 - Lamin A/C globular tail domain
  • 0.01522Inherited
    90229,90229
  • 90229 - CCCH zinc finger
  • 90229 - CCCH zinc finger
  • 0.03358Inherited
    52540,90123
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 90123 - ABC transporter transmembrane region
  • 0.04074Inherited
    49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.08062Inherited
    90123,52540
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.3316Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    54585,52540,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    50692,54585,52540
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.00007086Direct
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.00007458Direct
    48726,48726,49265
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.0001479Direct
    74788,75632,46785
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0.0005191Direct
    81296,81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 81296 - E set domains
  • 0.0007274Direct
    48452,48452,48452
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 0.0007274Direct
    48592,54849,52029
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.0007425Direct
    82895,82895,82895
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 0.001586Inherited
    52540,90123,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.04074Inherited
    90123,52540,90123
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 90123 - ABC transporter transmembrane region
  • 0.04074Inherited
    49313,49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.08062Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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