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Worm Phenotype (WP): organ system physiology variant
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Phenotype Ontology
Like Gene Ontology (GO), phenotypy ontology classifies and organizes gene-mutant/null phenotypic information from the very general at the top to more specific terms in the directed acyclic graph (DAG) by viewing an individual term as a node and its relations to parental terms (allowing for multiple parents) as directed edges. To navigate this hierarchy, we display all parental phenotypic terms to the current phenotypic term of interest ordered by their shortest distances to the current term. Also, only direct children phenotypic terms of the current phenotypic term are listed. Phenotype ontologies we have incorporated are as follows:
- Disease Ontology (DO) Ontology (DO) DO semantically integrates disease and medical vocabularies through extensive cross mapping of DO terms to MeSH, ICD, NCI thesaurus, SNOMED and OMIM.
- Human Phenotype (HP) Ontology (HP) HP captures phenotypic abnormalities that are described in OMIM, along with the corresponding disease-causing genes. It includes three complementary biological concepts: Mode_of_Inheritance (MI), ONset_and_clinical_course (ON), and Phenotypic_Abnormality (PA).
- Mouse Phenotype (MP) Ontology (MP) MP describes phenotypes of the mouse after a specific gene is genetically disrupted. Using it, Mouse Genome Informatics (MGI) provides high-coverate gene-level phenotypes for the mouse.
- Worm Phenotype (WP) Ontology (WP) WP classifies and organizes phenotype descriptions for C. elegans and other nematodes. Using it, WormBase provides primary resource for phenotype annotations for C. elegans.
- Yeast Phenotype (YP) Ontology (YP) Based on YP which is the major contributor to the Ascomycete phenotype ontology, Saccharomyces Genome Database (SGD) provides single mutant phenotypes for every gene in the yeast genome.
- Fly Phenotype (FP) Ontology (FP) FP refers to FlyBase controlled vocabulary. Specifically, a structured controlled vocabulary is used for the annotation of alleles (for their mutagen etc) in FlyBase.
- Fly Anatomy (FA) Ontology (FA) FA is a structured controlled vocabulary of the anatomy of Drosophila melanogaster, used for the description of phenotypes and where a gene is expressed.
- Zebrafish Anatomy (ZA) Ontology (ZA) ZA displays anatomical terms of the zebrafish using standard anatomical nomenclature, together with affected genes.
- Xenopus Anatomy (XA) Ontology (XA) XA represents the lineage of tissues and the timing of development for frogs (Xenopus laevis and Xenopus tropicalis). It is used to annotate Xenopus gene expression patterns and mutant and morphant phenotypes.
- Arabidopsis Plant Ontology (AP) Ontology (AP) As a major contributor to Plant Ontology which describes plant anatomical and morphological structures (AN) and growth and developmental stages (DE), the Arabidopsis Information Resource (TAIR) provides arabidopsis plant ontology annotations for the model higher plant Arabidopsis thaliana.
- Enzyme Commission (EC) Ontology (EC) Each enzyme is allocated a four-digit EC number, the first three digits of which define the reaction catalysed and the fourth of which is a unique identifier (serial number). Each enzyme is also assigned a systematic name that uniquely defines the reaction catalysed.
- DrugBank ATC (DB) Ontology (DB) In the Anatomical Therapeutic Chemical (ATC) classification system, drugs are classified in groups at five different levels according to the organ or system (1st level, anatomical main group) on which they act and their therapeutic (2nd level, therapeutic subgroup), pharmacological (3rd level, pharmacological subgroup) and chemical properties (4th level, chemical subgroup; 5th level, chemical substance). Only drugs in DrugBank are considered.
- UniProtKB KeyWords (KW) Ontology (KW) Keywords in UniProtKB are controlled vocabulary, providing a summary of the entry content and are used to index UniProtKB/Swiss-Prot entries based on 10 categories (the category "Technical term" being excluded here). Each keyword is attributed manually to UniProtKB/Swiss-Prot entries and automatically to UniProtKB/TrEMBL entries (according to specific annotation rules).
- UniProtKB UniPathway (UP) Ontology (UP) UP is a fully manually curated resource for the representation and annotation of metabolic pathways, being used as controlled vocabulary for pathway annotation in UniProtKB.
Structural Domain Phenotype Ontology and its Annotations
Structural Classification of Proteins (SCOP) classifies evolutionary-related domains into Superfamily level and Family level. Using the phenotype ontologies above, we have generated the domain-centric phenotype annotations, and further identified those phenotype terms which are the most informative to annotate SCOP domains. Promisingly, domain-centric phenotypic annotations can serve as an alternative starting point to explore genotype-phenotype relationships. We provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.
- Structural Domain Disease Ontology (DO) Ontology (SDDO) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DO.txt, and the corresponding ontology:SDDO.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Human Phenotype (HP) Ontology (SDHP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2HP.txt, and the corresponding ontology:SDHP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Mouse Phenotype (MP) Ontology (SDMP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2MP.txt, and the corresponding ontology:SDMP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Worm Phenotype (WP) Ontology (SDWP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2WP.txt, and the corresponding ontology:SDWP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Yeast Phenotype (YP) Ontology (SDYP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2YP.txt, and the corresponding ontology:SDYP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Fly Phenotype (FP) Ontology (SDFP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FP.txt, and the corresponding ontology:SDFP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Fly Anatomy (FA) Ontology (SDFA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FA.txt, and the corresponding ontology:SDFA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Zebrafish Anatomy (ZA) Ontology (SDZA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2ZA.txt, and the corresponding ontology:SDZA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Xenopus Anatomy (XA) Ontology (SDXA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2XA.txt, and the corresponding ontology:SDXA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Arabidopsis Plant Ontology (AP) Ontology (SDAP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2AP.txt, and the corresponding ontology:SDAP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Enzyme Commission (EC) Ontology (SDEC) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2EC.txt, and the corresponding ontology:SDEC.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain DrugBank ATC (DB) Ontology (SDDB) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DB.txt, and the corresponding ontology:SDDB.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain UniProtKB KeyWords (KW) Ontology (SDKW) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2KW.txt, and the corresponding ontology:SDKW.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain UniProtKB UniPathway (UP) Ontology (SDUP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2UP.txt, and the corresponding ontology:SDUP.txt) and mysql tables (Domain2PO.sql.gz).
Supra-domain Phenotype Ontology and its Annotations
Although domain-centric annotations hold great promise in describing phenotypic nature of independent domains, most domains themselves may not just work alone. In multi-domain proteins, they may be combined together to form distinct domain architectures. The recombination of the existing domains is considered as one of major driving forces for phenotypic diversificaation. As an extension, we have also generated supra-domain phenotype ontology and its annotations. Compared to domain-centric phenotype ontology and annotations (SCOP domains at the Superfamily level and Family level), this version focuses on supra-domains and individual SCOP domains ONLY at the Superfamily level. Besides, in terms of individual superfamilies, their annotations from the domain-centric version may be different from those from supra-domains version. Depending on your focus, the former should be used for the consideration of both the Superfamily level and Family level, otherwise the latter should be used if you are interested in domain combinations. Also, we provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.
- Supra-domain Domain Disease Ontology (DO) Ontology (SPDO) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DO.txt, and the corresponding ontology:SPDO.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Human Phenotype (HP) Ontology (SPHO) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2HP.txt, and the corresponding ontology:SPHO.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Mouse Phenotype (MP) Ontology (SPMP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2MP.txt, and the corresponding ontology:SPMP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Worm Phenotype (WP) Ontology (SPWP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2WP.txt, and the corresponding ontology:SPWP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Yeast Phenotype (YP) Ontology (SPYP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2YP.txt, and the corresponding ontology:SPYP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Fly Phenotype (FP) Ontology (SPFP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FP.txt, and the corresponding ontology:SPFP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Fly Anatomy (FA) Ontology (SPFA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FA.txt, and the corresponding ontology:SPFA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Zebrafish Anatomy (ZA) Ontology (SPZA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2ZA.txt, and the corresponding ontology:SPZA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Xenopus Anatomy (XA) Ontology (SPXA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2XA.txt, and the corresponding ontology:SPXA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Arabidopsis Plant Ontology (AP) Ontology (SPAP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2AP.txt, and the corresponding ontology:SPAP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Enzyme Commission (EC) Ontology (SPEC) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2EC.txt, and the corresponding ontology:SPEC.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain DrugBank ATC (DB) Ontology (SPDB) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DB.txt, and the corresponding ontology:SPDB.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain UniProtKB KeyWords (KW) Ontology (SPKW) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2KW.txt, and the corresponding ontology:SPKW.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain UniProtKB UniPathway (UP) Ontology (SPUP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2UP.txt, and the corresponding ontology:SPUP.txt) and mysql tables (SP2PO.sql.gz).
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Superfamily(show details)
Superfamily domains annotated to this WP term (Not in SDWP)
Highlighted in gray are those with FDR_all>0.001
SCOP term | FDR (all) | Annotation (direct or inherited) |
SCP-like | 0 | DIRECT |
CAD & PB1 domains | 0 | DIRECT |
Nudix | 0 | DIRECT |
FtsH protease domain-like | 0 | DIRECT |
Tubby C-terminal domain-like | 0 | DIRECT |
Thioesterase/thiol ester dehydrase-isomerase | 0 | DIRECT |
TK C-terminal domain-like | 0 | DIRECT |
Ribosomal protein L1 | 0 | DIRECT |
RBP11-like subunits of RNA polymerase | 0 | DIRECT |
Ribosomal proteins S24e, L23 and L15e | 0 | DIRECT |
Purple acid phosphatase, N-terminal domain | 0 | DIRECT |
Heme-dependent catalase-like | 0 | DIRECT |
Sema domain | 0 | DIRECT |
RUN domain-like | 0 | DIRECT |
Hairpin loop containing domain-like | 0 | DIRECT |
Ferritin-like | 0 | DIRECT |
LysM domain | 0 | DIRECT |
Retrovirus zinc finger-like domains | 0 | DIRECT |
Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
NHL repeat | 0 | DIRECT |
CalX-like | 0 | DIRECT |
Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | DIRECT |
Cysteine-rich DNA binding domain, (DM domain) | 0 | DIRECT |
SGNH hydrolase | 0 | DIRECT |
Cystatin/monellin | 0 | DIRECT |
CBD9-like | 0 | DIRECT |
Transcription factor IIA (TFIIA), beta-barrel domain | 0 | DIRECT |
Multidrug resistance efflux transporter EmrE | 0 | DIRECT |
Pectin lyase-like | 0 | DIRECT |
Cation efflux protein transmembrane domain-like | 0 | DIRECT |
SMAD/FHA domain | 0 | DIRECT |
Alpha-L RNA-binding motif | 0 | DIRECT |
Glycosyl hydrolase domain | 0 | DIRECT |
SAM/Pointed domain | 0 | DIRECT |
Galactose mutarotase-like | 0 | DIRECT |
Mitochondrial cytochrome c oxidase subunit VIc | 0 | DIRECT |
alpha-catenin/vinculin-like | 0 | DIRECT |
AN1-like Zinc finger | 0 | DIRECT |
MIR domain | 0 | DIRECT |
Folate-binding domain | 0 | DIRECT |
Ribosomal protein S18 | 0 | DIRECT |
Lysozyme-like | 0 | DIRECT |
Formate/glycerate dehydrogenase catalytic domain-like | 0 | DIRECT |
PUA domain-like | 0 | DIRECT |
SH3-domain | 0 | DIRECT |
Zn-finger domain of Sec23/24 | 0 | DIRECT |
alpha-helical ferredoxin | 0 | DIRECT |
Thiolase-like | 0 | DIRECT |
Creatinase/aminopeptidase | 0 | DIRECT |
Cyclophilin-like | 0 | DIRECT |
Calponin-homology domain, CH-domain | 0 | DIRECT |
Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
HRDC-like | 0 | DIRECT |
Aminomethyltransferase beta-barrel domain | 0 | DIRECT |
Carbohydrate phosphatase | 0 | DIRECT |
PLC-like phosphodiesterases | 0 | DIRECT |
Lipocalins | 0 | DIRECT |
Integrin domains | 0 | DIRECT |
Aquaporin-like | 0 | DIRECT |
Tropomyosin | 0 | DIRECT |
ADP-ribosylation | 0 | DIRECT |
BSD domain-like | 0 | DIRECT |
GroEL equatorial domain-like | 0 | DIRECT |
SAND domain-like | 0 | DIRECT |
t-snare proteins | 0 | DIRECT |
ArfGap/RecO-like zinc finger | 0 | DIRECT |
Acyl-CoA binding protein | 0 | DIRECT |
R3H domain | 0 | DIRECT |
FMN-linked oxidoreductases | 0 | DIRECT |
UBA-like | 0 | DIRECT |
Immunoglobulin | 0 | DIRECT |
Nucleotidyltransferase | 0 | DIRECT |
ACP-like | 0 | DIRECT |
Nucleic acid-binding proteins | 0 | DIRECT |
Actin depolymerizing proteins | 0 | DIRECT |
NAD(P)-linked oxidoreductase | 0 | DIRECT |
PH domain-like | 0 | DIRECT |
Bactericidal permeability-increasing protein, BPI | 0 | DIRECT |
RuvA domain 2-like | 0 | DIRECT |
DPP6 N-terminal domain-like | 0 | DIRECT |
Cysteine-rich domain | 0 | DIRECT |
Carbon-nitrogen hydrolase | 0 | DIRECT |
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0 | DIRECT |
Osmotin, thaumatin-like protein | 0 | DIRECT |
Nucleoside diphosphate kinase, NDK | 0 | DIRECT |
Chromo domain-like | 0 | DIRECT |
Eukaryotic type KH-domain (KH-domain type I) | 0 | DIRECT |
Phosphoglycerate mutase-like | 0 | DIRECT |
PGBD-like | 0 | DIRECT |
Glycerol-3-phosphate (1)-acyltransferase | 0 | DIRECT |
AraD/HMP-PK domain-like | 0 | DIRECT |
BAR/IMD domain-like | 0 | DIRECT |
HLH, helix-loop-helix DNA-binding domain | 0 | DIRECT |
Transducin (alpha subunit), insertion domain | 0 | DIRECT |
Calcium ATPase, transmembrane domain M | 0 | DIRECT |
ALDH-like | 0 | DIRECT |
Proton glutamate symport protein | 0 | DIRECT |
Ribosomal L27 protein-like | 0 | DIRECT |
Cation efflux protein cytoplasmic domain-like | 0 | DIRECT |
beta-lactamase/transpeptidase-like | 0 | DIRECT |
Calcium ATPase, transduction domain A | 0 | DIRECT |
Ras GEF | 0 | DIRECT |
Mitochondrial carrier | 0 | DIRECT |
Acyl-CoA N-acyltransferases (Nat) | 0 | DIRECT |
Di-copper centre-containing domain | 0 | DIRECT |
Cupredoxins | 0 | DIRECT |
ISP domain | 0 | DIRECT |
SMR domain-like | 0 | DIRECT |
Aldolase | 0 | DIRECT |
SIS domain | 0 | DIRECT |
3-carboxy-cis,cis-mucoante lactonizing enzyme | 0 | DIRECT |
PurM N-terminal domain-like | 0 | DIRECT |
EF-G C-terminal domain-like | 0 | DIRECT |
Thiamin diphosphate-binding fold (THDP-binding) | 0 | DIRECT |
Galactose oxidase, central domain | 0 | DIRECT |
Class I glutamine amidotransferase-like | 0 | DIRECT |
C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
MgtE membrane domain-like | 0 | DIRECT |
Profilin (actin-binding protein) | 0 | DIRECT |
CO dehydrogenase molybdoprotein N-domain-like | 0 | DIRECT |
ENTH/VHS domain | 0 | DIRECT |
Families 57/38 glycoside transferase middle domain | 0 | DIRECT |
EGF/Laminin | 0 | DIRECT |
Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
SNARE-like | 0 | DIRECT |
CRAL/TRIO domain | 0 | DIRECT |
DHS-like NAD/FAD-binding domain | 0 | DIRECT |
N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0 | DIRECT |
vWA-like | 0 | DIRECT |
Activating enzymes of the ubiquitin-like proteins | 0 | DIRECT |
Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
Succinyl-CoA synthetase domains | 0 | DIRECT |
HSP90 C-terminal domain | 0 | DIRECT |
Bet v1-like | 0 | DIRECT |
CCCH zinc finger | 0 | DIRECT |
RCC1/BLIP-II | 0 | DIRECT |
Prefoldin | 0 | DIRECT |
WGR domain-like | 0 | DIRECT |
cAMP-binding domain-like | 0 | DIRECT |
CRAL/TRIO N-terminal domain | 0 | DIRECT |
Kringle-like | 0 | DIRECT |
4Fe-4S ferredoxins | 0 | DIRECT |
Metal cation-transporting ATPase, ATP-binding domain N | 0 | DIRECT |
Doublecortin (DC) | 0 | DIRECT |
NAD kinase/diacylglycerol kinase-like | 0 | DIRECT |
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | DIRECT |
Ricin B-like lectins | 0 | DIRECT |
FabD/lysophospholipase-like | 0 | DIRECT |
eIF4e-like | 0 | DIRECT |
Citrate synthase | 0 | DIRECT |
Class II aaRS and biotin synthetases | 0 | DIRECT |
ClpP/crotonase | 0 | DIRECT |
beta-sandwich domain of Sec23/24 | 0 | DIRECT |
Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
Phospholipase A2, PLA2 | 0 | DIRECT |
BolA-like | 0 | DIRECT |
Terpenoid synthases | 0 | DIRECT |
DNA repair protein MutS, domain III | 0 | DIRECT |
NTF2-like | 0 | DIRECT |
Oxysterol-binding protein-like | 0 | DIRECT |
TIMP-like | 0 | DIRECT |
Aminoacid dehydrogenase-like, N-terminal domain | 0 | DIRECT |
F1F0 ATP synthase subunit C | 0 | DIRECT |
LEM domain | 0 | DIRECT |
PHM/PNGase F | 0 | DIRECT |
Alkaline phosphatase-like | 0 | DIRECT |
DBL homology domain (DH-domain) | 0 | DIRECT |
Actin-like ATPase domain | 0 | DIRECT |
PreATP-grasp domain | 0 | DIRECT |
PLP-binding barrel | 0 | DIRECT |
Mss4-like | 0 | DIRECT |
5' to 3' exonuclease, C-terminal subdomain | 0 | DIRECT |
6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | DIRECT |
FAD-linked reductases, C-terminal domain | 0 | DIRECT |
PK beta-barrel domain-like | 0 | DIRECT |
Calpain large subunit, middle domain (domain III) | 0 | DIRECT |
Ypt/Rab-GAP domain of gyp1p | 0 | DIRECT |
Phoshotransferase/anion transport protein | 0 | DIRECT |
Regulator of G-protein signaling, RGS | 0 | DIRECT |
Tautomerase/MIF | 0 | DIRECT |
VPS9 domain | 0 | DIRECT |
Bromodomain | 0 | DIRECT |
Glutamine synthetase/guanido kinase | 0 | DIRECT |
Creatinase/prolidase N-terminal domain | 0 | DIRECT |
Arginase/deacetylase | 0 | DIRECT |
Tudor/PWWP/MBT | 0 | DIRECT |
Surp module (SWAP domain) | 0 | DIRECT |
Cytidine deaminase-like | 0 | DIRECT |
Complement control module/SCR domain | 0 | DIRECT |
Leukotriene A4 hydrolase N-terminal domain | 0 | DIRECT |
SWIB/MDM2 domain | 0 | DIRECT |
Spectrin repeat | 0 | DIRECT |
L30e-like | 0 | DIRECT |
The spindle assembly checkpoint protein mad2 | 0 | DIRECT |
Amidase signature (AS) enzymes | 0 | DIRECT |
SPOC domain-like | 0 | DIRECT |
Phosphoglucomutase, first 3 domains | 0 | DIRECT |
PP2C-like | 0 | DIRECT |
Tim10-like | 0 | DIRECT |
HIT-like | 0 | DIRECT |
Cystine-knot cytokines | 0 | DIRECT |
Skp1 dimerisation domain-like | 0 | DIRECT |
FAD-linked oxidases, C-terminal domain | 0 | DIRECT |
Rap/Ran-GAP | 0 | DIRECT |
Roadblock/LC7 domain | 0 | DIRECT |
Kelch motif | 0 | DIRECT |
PIN domain-like | 0 | DIRECT |
BEACH domain | 0 | DIRECT |
DEATH domain | 0 | DIRECT |
p53-like transcription factors | 0 | DIRECT |
YWTD domain | 0 | DIRECT |
S-adenosylmethionine synthetase | 0 | DIRECT |
Multidrug efflux transporter AcrB transmembrane domain | 0 | DIRECT |
YbiA-like | 0 | DIRECT |
Single hybrid motif | 0 | DIRECT |
Lipovitellin-phosvitin complex, superhelical domain | 0 | DIRECT |
Fibronectin type III | 0 | DIRECT |
Nucleoporin domain | 0 | DIRECT |
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
MFPT repeat-like | 0 | DIRECT |
Ganglioside M2 (gm2) activator | 0 | DIRECT |
GAS2 domain-like | 0 | DIRECT |
Terpenoid cyclases/Protein prenyltransferases | 0 | DIRECT |
SMAD MH1 domain | 0 | DIRECT |
PEP carboxykinase N-terminal domain | 0 | DIRECT |
Tricorn protease domain 2 | 0 | DIRECT |
Hormone receptor domain | 0 | DIRECT |
Phospholipase D/nuclease | 0 | DIRECT |
GroEL-intermediate domain like | 0 | DIRECT |
Cytochrome b5-like heme/steroid binding domain | 0 | DIRECT |
Sec1/munc18-like (SM) proteins | 0 | DIRECT |
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
Carbonic anhydrase | 0 | DIRECT |
B-box zinc-binding domain | 0 | DIRECT |
Acid proteases | 0 | DIRECT |
eIF1-like | 0 | DIRECT |
Clavaminate synthase-like | 0 | DIRECT |
Band 7/SPFH domain | 0 | DIRECT |
Quinoprotein alcohol dehydrogenase-like | 0 | DIRECT |
ARID-like | 0 | DIRECT |
Periplasmic binding protein-like I | 0 | DIRECT |
Cap-Gly domain | 0 | DIRECT |
Isocitrate/Isopropylmalate dehydrogenase-like | 0 | DIRECT |
GAT-like domain | 0 | DIRECT |
Calcium-dependent phosphotriesterase | 0 | DIRECT |
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
Transducin (heterotrimeric G protein), gamma chain | 0 | DIRECT |
alpha/beta knot | 0 | DIRECT |
Sec63 N-terminal domain-like | 0 | DIRECT |
Sec7 domain | 0 | DIRECT |
HAD-like | 0 | DIRECT |
beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | DIRECT |
Riboflavin synthase domain-like | 0 | DIRECT |
Metallo-hydrolase/oxidoreductase | 0 | DIRECT |
Phosphoenolpyruvate/pyruvate domain | 0 | DIRECT |
14-3-3 protein | 0 | DIRECT |
Nop domain | 0 | DIRECT |
Tubulin nucleotide-binding domain-like | 0 | DIRECT |
Rhodanese/Cell cycle control phosphatase | 0 | DIRECT |
LDH C-terminal domain-like | 0 | DIRECT |
Plexin repeat | 0 | DIRECT |
Supernatant protein factor (SPF), C-terminal domain | 0 | DIRECT |
Carboxypeptidase regulatory domain-like | 0 | DIRECT |
N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
PR-1-like | 0 | DIRECT |
Cytochrome c | 0 | DIRECT |
HD-domain/PDEase-like | 0 | DIRECT |
WW domain | 0 | DIRECT |
ADC-like | 0 | DIRECT |
LDL receptor-like module | 0 | DIRECT |
Blood coagulation inhibitor (disintegrin) | 0 | DIRECT |
Formin homology 2 domain (FH2 domain) | 0 | DIRECT |
C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
FAD/NAD(P)-binding domain | 0 | DIRECT |
Molybdenum cofactor biosynthesis proteins | 0 | DIRECT |
PAP/OAS1 substrate-binding domain | 0 | DIRECT |
Helical domain of Sec23/24 | 0 | DIRECT |
TAZ domain | 0 | DIRECT |
Flavoproteins | 0 | DIRECT |
Subtilisin-like | 0 | DIRECT |
Translation proteins SH3-like domain | 0 | DIRECT |
Ribonuclease PH domain 2-like | 0 | DIRECT |
GroES-like | 0 | DIRECT |
Pepsin inhibitor-3 | 0 | DIRECT |
Inhibitor of apoptosis (IAP) repeat | 0 | DIRECT |
Small-conductance potassium channel | 0 | DIRECT |
Nucleotide cyclase | 0 | DIRECT |
HSP20-like chaperones | 0 | DIRECT |
Hypothetical protein c14orf129, hspc210 | 0 | DIRECT |
CBS-domain pair | 0 | DIRECT |
Integrin alpha N-terminal domain | 0 | DIRECT |
E2F-DP heterodimerization region | 0 | DIRECT |
lambda repressor-like DNA-binding domains | 0 | DIRECT |
2Fe-2S ferredoxin-like | 0 | DIRECT |
HIT/MYND zinc finger-like | 0 | DIRECT |
BPTI-like | 0 | DIRECT |
RmlC-like cupins | 0 | DIRECT |
HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
Cdc48 domain 2-like | 0 | DIRECT |
Nucleotide-diphospho-sugar transferases | 0 | DIRECT |
Thyroglobulin type-1 domain | 0 | DIRECT |
Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
Spermadhesin, CUB domain | 0 | DIRECT |
Glycoside hydrolase/deacetylase | 0 | DIRECT |
PABC (PABP) domain | 0 | DIRECT |
Heme-dependent peroxidases | 0 | DIRECT |
Transcription factor IIA (TFIIA), alpha-helical domain | 0 | DIRECT |
SAICAR synthase-like | 0 | DIRECT |
L domain-like | 0 | DIRECT |
Rhomboid-like | 0 | DIRECT |
Restriction endonuclease-like | 0 | DIRECT |
Guanido kinase N-terminal domain | 0 | DIRECT |
Chitinase insertion domain | 0 | DIRECT |
Clathrin adaptor appendage domain | 0 | DIRECT |
Ran binding protein zinc finger-like | 0 | DIRECT |
Cu,Zn superoxide dismutase-like | 0 | DIRECT |
Adenine nucleotide alpha hydrolases-like | 0 | DIRECT |
Radical SAM enzymes | 0 | DIRECT |
Ribosomal protein L10-like | 0 | DIRECT |
S-adenosyl-L-methionine-dependent methyltransferases | 0 | DIRECT |
Glycolipid transfer protein, GLTP | 0 | DIRECT |
Hemopexin-like domain | 0 | DIRECT |
Mob1/phocein | 0 | DIRECT |
Clc chloride channel | 0 | DIRECT |
DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
Tubulin C-terminal domain-like | 0 | DIRECT |
Smc hinge domain | 0 | DIRECT |
UBC-like | 0 | DIRECT |
SpoIIaa-like | 0 | DIRECT |
Serine protease inhibitors | 0 | DIRECT |
PYP-like sensor domain (PAS domain) | 0 | DIRECT |
Tetraspanin | 0 | DIRECT |
Bacterial exopeptidase dimerisation domain | 0 | DIRECT |
Frizzled cysteine-rich domain | 0 | DIRECT |
Periplasmic binding protein-like II | 0 | DIRECT |
Chaperone J-domain | 0 | DIRECT |
Caspase-like | 0 | DIRECT |
Ribulose-phoshate binding barrel | 0 | DIRECT |
Annexin | 0 | DIRECT |
HCP-like | 0 | DIRECT |
MIT domain | 0 | DIRECT |
Class II aaRS ABD-related | 0 | DIRECT |
PEBP-like | 0 | DIRECT |
Concanavalin A-like lectins/glucanases | 0 | DIRECT |
Putative DNA-binding domain | 0 | DIRECT |
SAP domain | 0 | DIRECT |
WWE domain | 0 | DIRECT |
PDZ domain-like | 0 | DIRECT |
EB1 dimerisation domain-like | 0 | DIRECT |
Ammonium transporter | 0 | DIRECT |
Zinc beta-ribbon | 0 | DIRECT |
Pseudouridine synthase | 0 | DIRECT |
Seven-hairpin glycosidases | 0 | DIRECT |
Translation proteins | 0 | DIRECT |
Myosin rod fragments | 0 | DIRECT |
PRTase-like | 0 | DIRECT |
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | DIRECT |
Kix domain of CBP (creb binding protein) | 0 | DIRECT |
Subdomain of clathrin and coatomer appendage domain | 0 | DIRECT |
ABC transporter transmembrane region | 0 | DIRECT |
Sm-like ribonucleoproteins | 0 | DIRECT |
SNARE fusion complex | 0 | DIRECT |
HMG-box | 0 | DIRECT |
Pentein | 0 | DIRECT |
FAD-dependent thiol oxidase | 0 | DIRECT |
FAD-binding/transporter-associated domain-like | 0 | DIRECT |
Hedgehog/intein (Hint) domain | 0 | DIRECT |
GHMP Kinase, C-terminal domain | 0 | DIRECT |
Ankyrin repeat | 0 | DIRECT |
PurM C-terminal domain-like | 0 | DIRECT |
Ribosomal protein S10 | 0 | DIRECT |
Acyl-CoA dehydrogenase NM domain-like | 0 | DIRECT |
Intermediate filament protein, coiled coil region | 0 | DIRECT |
Molybdenum cofactor-binding domain | 0 | DIRECT |
C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
GroEL apical domain-like | 0 | DIRECT |
Domain of poly(ADP-ribose) polymerase | 0 | DIRECT |
PX domain | 0 | DIRECT |
Actin-crosslinking proteins | 0 | DIRECT |
Second domain of FERM | 0 | DIRECT |
Fibrinogen C-terminal domain-like | 0 | DIRECT |
Glutathione synthetase ATP-binding domain-like | 0 | DIRECT |
GYF domain | 0 | DIRECT |
Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
DNase I-like | 0 | DIRECT |
Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | DIRECT |
Growth factor receptor domain | 0 | DIRECT |
Acid phosphatase/Vanadium-dependent haloperoxidase | 0 | DIRECT |
PEP carboxykinase-like | 0 | DIRECT |
TGS-like | 0 | DIRECT |
Diaminopimelate epimerase-like | 0 | DIRECT |
Troponin coil-coiled subunits | 0 | DIRECT |
MOSC N-terminal domain-like | 0 | DIRECT |
FF domain | 0 | DIRECT |
Ribokinase-like | 0 | DIRECT |
Polo-box domain | 0 | DIRECT |
ThrRS/AlaRS common domain | 0 | DIRECT |
Protease propeptides/inhibitors | 0 | DIRECT |
FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | DIRECT |
BRCT domain | 0 | DIRECT |
CO dehydrogenase ISP C-domain like | 0 | DIRECT |
DNA clamp | 0 | DIRECT |
SET domain | 0 | DIRECT |
Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | DIRECT |
Translational machinery components | 0 | DIRECT |
Invertebrate chitin-binding proteins | 0 | DIRECT |
Rudiment single hybrid motif | 0 | DIRECT |
L-aspartase-like | 0 | DIRECT |
Hect, E3 ligase catalytic domain | 0 | DIRECT |
DNA ligase/mRNA capping enzyme, catalytic domain | 0 | DIRECT |
Outer arm dynein light chain 1 | 0 | DIRECT |
ValRS/IleRS/LeuRS editing domain | 0 | DIRECT |
Six-hairpin glycosidases | 0 | DIRECT |
CoA-dependent acyltransferases | 0 | DIRECT |
Glutamine synthetase, N-terminal domain | 0 | DIRECT |
Elafin-like | 0 | DIRECT |
Cadherin-like | 0 | DIRECT |
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | DIRECT |
Metallo-dependent hydrolases | 0 | DIRECT |
Nucleotide-binding domain | 0 | DIRECT |
Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | DIRECT |
NagB/RpiA/CoA transferase-like | 0 | DIRECT |
KA1-like | 0 | DIRECT |
ARM repeat | 0.08004 | INHERITED FROM: germ cell physiology variant || brood size variant || epithelial system physiology variant |
RNA-binding domain, RBD | 0.2112 | INHERITED FROM: sterile F1 || brood size variant |
PapD-like | 0.2487 | INHERITED FROM: sterile progeny |
Nicotinic receptor ligand binding domain-like | 0.2761 | INHERITED FROM: synaptic transmission variant || coelomic system physiology variant || coelomocyte uptake defective || transmission of nerve impulse variant || nervous system physiology variant || coelomocyte physiology variant |
Voltage-gated potassium channels | 0.3243 | INHERITED FROM: muscle cell activity variant |
Neurotransmitter-gated ion-channel transmembrane pore | 0.329 | INHERITED FROM: synaptic transmission variant || coelomic system physiology variant || coelomocyte uptake defective || transmission of nerve impulse variant || nervous system physiology variant || coelomocyte physiology variant |
Ubiquitin-like | 0.3699 | INHERITED FROM: muscle system physiology variant || body muscle dystrophy || muscle cell physiology variant |
Metallo-dependent phosphatases | 0.4365 | INHERITED FROM: germ cell resistant ionizing radiation || radiation induced germ cell apoptosis resistant |
FYVE/PHD zinc finger | 0.5315 | INHERITED FROM: coelomic system physiology variant || coelomocyte uptake defective || transgenerational loss of fertility || coelomocyte physiology variant |
EF-hand | 0.625 | INHERITED FROM: somatic gonad physiology variant || muscle system physiology variant || gonad sheath contractions variant || somatic sheath physiology variant || muscle cell physiology variant |
WD40 repeat-like | 0.6668 | INHERITED FROM: germ cell physiology variant || brood size variant || reduced brood size |
TPR-like | 0.6882 | INHERITED FROM: male gonad development variant |
GTPase activation domain, GAP | 0.7397 | INHERITED FROM: muscle cell attachment variant || muscle system physiology variant || muscle cell physiology variant |
P-loop containing nucleoside triphosphate hydrolases | 0.7413 | INHERITED FROM: germ cell physiology variant || brood size variant || male gonad development variant || postsynaptic region physiology variant || nervous system physiology variant |
Saposin | 0.7903 | INHERITED FROM: germ cell ionizing radiation response variant || germ cell resistant ionizing radiation || radiation induced germ cell apoptosis resistant |
(Phosphotyrosine protein) phosphatases II | 0.8216 | INHERITED FROM: muscle cell attachment variant |
"Winged helix" DNA-binding domain | 0.889 | INHERITED FROM: male gonad development variant || body muscle dystrophy || muscle dystrophy || germline mortal |
RING/U-box | 0.9098 | INHERITED FROM: germ cell hypersensitive ionizing radiation || germ cell ionizing radiation response variant |
Lamin A/C globular tail domain | 0.9465 | INHERITED FROM: muscle system physiology variant |
PLP-dependent transferases | 0.9539 | INHERITED FROM: germ cell resistant ionizing radiation || radiation induced germ cell apoptosis resistant |
Protein kinase-like (PK-like) | 1 | INHERITED FROM: muscle system physiology variant || body muscle dystrophy || muscle cell physiology variant |
SH2 domain | 1 | INHERITED FROM: muscle cell attachment variant || muscle system physiology variant || muscle cell physiology variant |
SCOP term | FDR (all) | Annotation (direct or inherited) |
SCP-like | 0 | Direct |
CAD & PB1 domains | 0 | Direct |
Nudix | 0 | Direct |
FtsH protease domain-like | 0 | Direct |
Tubby C-terminal domain-like | 0 | Direct |
Thioesterase/thiol ester dehydrase-isomerase | 0 | Direct |
TK C-terminal domain-like | 0 | Direct |
Ribosomal protein L1 | 0 | Direct |
RBP11-like subunits of RNA polymerase | 0 | Direct |
Ribosomal proteins S24e, L23 and L15e | 0 | Direct |
Purple acid phosphatase, N-terminal domain | 0 | Direct |
Heme-dependent catalase-like | 0 | Direct |
Sema domain | 0 | Direct |
RUN domain-like | 0 | Direct |
Hairpin loop containing domain-like | 0 | Direct |
Ferritin-like | 0 | Direct |
LysM domain | 0 | Direct |
Retrovirus zinc finger-like domains | 0 | Direct |
Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
NHL repeat | 0 | Direct |
CalX-like | 0 | Direct |
Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | Direct |
Cysteine-rich DNA binding domain, (DM domain) | 0 | Direct |
SGNH hydrolase | 0 | Direct |
Cystatin/monellin | 0 | Direct |
CBD9-like | 0 | Direct |
Transcription factor IIA (TFIIA), beta-barrel domain | 0 | Direct |
Multidrug resistance efflux transporter EmrE | 0 | Direct |
Pectin lyase-like | 0 | Direct |
Cation efflux protein transmembrane domain-like | 0 | Direct |
SMAD/FHA domain | 0 | Direct |
Alpha-L RNA-binding motif | 0 | Direct |
Glycosyl hydrolase domain | 0 | Direct |
SAM/Pointed domain | 0 | Direct |
Galactose mutarotase-like | 0 | Direct |
Mitochondrial cytochrome c oxidase subunit VIc | 0 | Direct |
alpha-catenin/vinculin-like | 0 | Direct |
AN1-like Zinc finger | 0 | Direct |
MIR domain | 0 | Direct |
Folate-binding domain | 0 | Direct |
Ribosomal protein S18 | 0 | Direct |
Lysozyme-like | 0 | Direct |
Formate/glycerate dehydrogenase catalytic domain-like | 0 | Direct |
PUA domain-like | 0 | Direct |
SH3-domain | 0 | Direct |
Zn-finger domain of Sec23/24 | 0 | Direct |
alpha-helical ferredoxin | 0 | Direct |
Thiolase-like | 0 | Direct |
Creatinase/aminopeptidase | 0 | Direct |
Cyclophilin-like | 0 | Direct |
Calponin-homology domain, CH-domain | 0 | Direct |
Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
HRDC-like | 0 | Direct |
Aminomethyltransferase beta-barrel domain | 0 | Direct |
Carbohydrate phosphatase | 0 | Direct |
PLC-like phosphodiesterases | 0 | Direct |
Lipocalins | 0 | Direct |
Integrin domains | 0 | Direct |
Aquaporin-like | 0 | Direct |
Tropomyosin | 0 | Direct |
ADP-ribosylation | 0 | Direct |
BSD domain-like | 0 | Direct |
GroEL equatorial domain-like | 0 | Direct |
SAND domain-like | 0 | Direct |
t-snare proteins | 0 | Direct |
ArfGap/RecO-like zinc finger | 0 | Direct |
Acyl-CoA binding protein | 0 | Direct |
R3H domain | 0 | Direct |
FMN-linked oxidoreductases | 0 | Direct |
UBA-like | 0 | Direct |
Immunoglobulin | 0 | Direct |
Nucleotidyltransferase | 0 | Direct |
ACP-like | 0 | Direct |
Nucleic acid-binding proteins | 0 | Direct |
Actin depolymerizing proteins | 0 | Direct |
NAD(P)-linked oxidoreductase | 0 | Direct |
PH domain-like | 0 | Direct |
Bactericidal permeability-increasing protein, BPI | 0 | Direct |
RuvA domain 2-like | 0 | Direct |
DPP6 N-terminal domain-like | 0 | Direct |
Cysteine-rich domain | 0 | Direct |
Carbon-nitrogen hydrolase | 0 | Direct |
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0 | Direct |
Osmotin, thaumatin-like protein | 0 | Direct |
Nucleoside diphosphate kinase, NDK | 0 | Direct |
Chromo domain-like | 0 | Direct |
Eukaryotic type KH-domain (KH-domain type I) | 0 | Direct |
Phosphoglycerate mutase-like | 0 | Direct |
PGBD-like | 0 | Direct |
Glycerol-3-phosphate (1)-acyltransferase | 0 | Direct |
AraD/HMP-PK domain-like | 0 | Direct |
BAR/IMD domain-like | 0 | Direct |
HLH, helix-loop-helix DNA-binding domain | 0 | Direct |
Transducin (alpha subunit), insertion domain | 0 | Direct |
Calcium ATPase, transmembrane domain M | 0 | Direct |
ALDH-like | 0 | Direct |
Proton glutamate symport protein | 0 | Direct |
Ribosomal L27 protein-like | 0 | Direct |
Cation efflux protein cytoplasmic domain-like | 0 | Direct |
beta-lactamase/transpeptidase-like | 0 | Direct |
Calcium ATPase, transduction domain A | 0 | Direct |
Ras GEF | 0 | Direct |
Mitochondrial carrier | 0 | Direct |
Acyl-CoA N-acyltransferases (Nat) | 0 | Direct |
Di-copper centre-containing domain | 0 | Direct |
Cupredoxins | 0 | Direct |
ISP domain | 0 | Direct |
SMR domain-like | 0 | Direct |
Aldolase | 0 | Direct |
SIS domain | 0 | Direct |
3-carboxy-cis,cis-mucoante lactonizing enzyme | 0 | Direct |
PurM N-terminal domain-like | 0 | Direct |
EF-G C-terminal domain-like | 0 | Direct |
Thiamin diphosphate-binding fold (THDP-binding) | 0 | Direct |
Galactose oxidase, central domain | 0 | Direct |
Class I glutamine amidotransferase-like | 0 | Direct |
C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
MgtE membrane domain-like | 0 | Direct |
Profilin (actin-binding protein) | 0 | Direct |
CO dehydrogenase molybdoprotein N-domain-like | 0 | Direct |
ENTH/VHS domain | 0 | Direct |
Families 57/38 glycoside transferase middle domain | 0 | Direct |
EGF/Laminin | 0 | Direct |
Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
SNARE-like | 0 | Direct |
CRAL/TRIO domain | 0 | Direct |
DHS-like NAD/FAD-binding domain | 0 | Direct |
N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0 | Direct |
vWA-like | 0 | Direct |
Activating enzymes of the ubiquitin-like proteins | 0 | Direct |
Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
Succinyl-CoA synthetase domains | 0 | Direct |
HSP90 C-terminal domain | 0 | Direct |
Bet v1-like | 0 | Direct |
CCCH zinc finger | 0 | Direct |
RCC1/BLIP-II | 0 | Direct |
Prefoldin | 0 | Direct |
WGR domain-like | 0 | Direct |
cAMP-binding domain-like | 0 | Direct |
CRAL/TRIO N-terminal domain | 0 | Direct |
Kringle-like | 0 | Direct |
4Fe-4S ferredoxins | 0 | Direct |
Metal cation-transporting ATPase, ATP-binding domain N | 0 | Direct |
Doublecortin (DC) | 0 | Direct |
NAD kinase/diacylglycerol kinase-like | 0 | Direct |
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | Direct |
Ricin B-like lectins | 0 | Direct |
FabD/lysophospholipase-like | 0 | Direct |
eIF4e-like | 0 | Direct |
Citrate synthase | 0 | Direct |
Class II aaRS and biotin synthetases | 0 | Direct |
ClpP/crotonase | 0 | Direct |
beta-sandwich domain of Sec23/24 | 0 | Direct |
Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
Phospholipase A2, PLA2 | 0 | Direct |
BolA-like | 0 | Direct |
Terpenoid synthases | 0 | Direct |
DNA repair protein MutS, domain III | 0 | Direct |
NTF2-like | 0 | Direct |
Oxysterol-binding protein-like | 0 | Direct |
TIMP-like | 0 | Direct |
Aminoacid dehydrogenase-like, N-terminal domain | 0 | Direct |
F1F0 ATP synthase subunit C | 0 | Direct |
LEM domain | 0 | Direct |
PHM/PNGase F | 0 | Direct |
Alkaline phosphatase-like | 0 | Direct |
DBL homology domain (DH-domain) | 0 | Direct |
Actin-like ATPase domain | 0 | Direct |
PreATP-grasp domain | 0 | Direct |
PLP-binding barrel | 0 | Direct |
Mss4-like | 0 | Direct |
5' to 3' exonuclease, C-terminal subdomain | 0 | Direct |
6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | Direct |
FAD-linked reductases, C-terminal domain | 0 | Direct |
PK beta-barrel domain-like | 0 | Direct |
Calpain large subunit, middle domain (domain III) | 0 | Direct |
Ypt/Rab-GAP domain of gyp1p | 0 | Direct |
Phoshotransferase/anion transport protein | 0 | Direct |
Regulator of G-protein signaling, RGS | 0 | Direct |
Tautomerase/MIF | 0 | Direct |
VPS9 domain | 0 | Direct |
Bromodomain | 0 | Direct |
Glutamine synthetase/guanido kinase | 0 | Direct |
Creatinase/prolidase N-terminal domain | 0 | Direct |
Arginase/deacetylase | 0 | Direct |
Tudor/PWWP/MBT | 0 | Direct |
Surp module (SWAP domain) | 0 | Direct |
Cytidine deaminase-like | 0 | Direct |
Complement control module/SCR domain | 0 | Direct |
Leukotriene A4 hydrolase N-terminal domain | 0 | Direct |
SWIB/MDM2 domain | 0 | Direct |
Spectrin repeat | 0 | Direct |
L30e-like | 0 | Direct |
The spindle assembly checkpoint protein mad2 | 0 | Direct |
Amidase signature (AS) enzymes | 0 | Direct |
SPOC domain-like | 0 | Direct |
Phosphoglucomutase, first 3 domains | 0 | Direct |
PP2C-like | 0 | Direct |
Tim10-like | 0 | Direct |
HIT-like | 0 | Direct |
Cystine-knot cytokines | 0 | Direct |
Skp1 dimerisation domain-like | 0 | Direct |
FAD-linked oxidases, C-terminal domain | 0 | Direct |
Rap/Ran-GAP | 0 | Direct |
Roadblock/LC7 domain | 0 | Direct |
Kelch motif | 0 | Direct |
PIN domain-like | 0 | Direct |
BEACH domain | 0 | Direct |
DEATH domain | 0 | Direct |
p53-like transcription factors | 0 | Direct |
YWTD domain | 0 | Direct |
S-adenosylmethionine synthetase | 0 | Direct |
Multidrug efflux transporter AcrB transmembrane domain | 0 | Direct |
YbiA-like | 0 | Direct |
Single hybrid motif | 0 | Direct |
Lipovitellin-phosvitin complex, superhelical domain | 0 | Direct |
Fibronectin type III | 0 | Direct |
Nucleoporin domain | 0 | Direct |
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
MFPT repeat-like | 0 | Direct |
Ganglioside M2 (gm2) activator | 0 | Direct |
GAS2 domain-like | 0 | Direct |
Terpenoid cyclases/Protein prenyltransferases | 0 | Direct |
SMAD MH1 domain | 0 | Direct |
PEP carboxykinase N-terminal domain | 0 | Direct |
Tricorn protease domain 2 | 0 | Direct |
Hormone receptor domain | 0 | Direct |
Phospholipase D/nuclease | 0 | Direct |
GroEL-intermediate domain like | 0 | Direct |
Cytochrome b5-like heme/steroid binding domain | 0 | Direct |
Sec1/munc18-like (SM) proteins | 0 | Direct |
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
Carbonic anhydrase | 0 | Direct |
B-box zinc-binding domain | 0 | Direct |
Acid proteases | 0 | Direct |
eIF1-like | 0 | Direct |
Clavaminate synthase-like | 0 | Direct |
Band 7/SPFH domain | 0 | Direct |
Quinoprotein alcohol dehydrogenase-like | 0 | Direct |
ARID-like | 0 | Direct |
Periplasmic binding protein-like I | 0 | Direct |
Cap-Gly domain | 0 | Direct |
Isocitrate/Isopropylmalate dehydrogenase-like | 0 | Direct |
GAT-like domain | 0 | Direct |
Calcium-dependent phosphotriesterase | 0 | Direct |
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
Transducin (heterotrimeric G protein), gamma chain | 0 | Direct |
alpha/beta knot | 0 | Direct |
Sec63 N-terminal domain-like | 0 | Direct |
Sec7 domain | 0 | Direct |
HAD-like | 0 | Direct |
beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | Direct |
Riboflavin synthase domain-like | 0 | Direct |
Metallo-hydrolase/oxidoreductase | 0 | Direct |
Phosphoenolpyruvate/pyruvate domain | 0 | Direct |
14-3-3 protein | 0 | Direct |
Nop domain | 0 | Direct |
Tubulin nucleotide-binding domain-like | 0 | Direct |
Rhodanese/Cell cycle control phosphatase | 0 | Direct |
LDH C-terminal domain-like | 0 | Direct |
Plexin repeat | 0 | Direct |
Supernatant protein factor (SPF), C-terminal domain | 0 | Direct |
Carboxypeptidase regulatory domain-like | 0 | Direct |
N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
PR-1-like | 0 | Direct |
Cytochrome c | 0 | Direct |
HD-domain/PDEase-like | 0 | Direct |
WW domain | 0 | Direct |
ADC-like | 0 | Direct |
LDL receptor-like module | 0 | Direct |
Blood coagulation inhibitor (disintegrin) | 0 | Direct |
Formin homology 2 domain (FH2 domain) | 0 | Direct |
C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
FAD/NAD(P)-binding domain | 0 | Direct |
Molybdenum cofactor biosynthesis proteins | 0 | Direct |
PAP/OAS1 substrate-binding domain | 0 | Direct |
Helical domain of Sec23/24 | 0 | Direct |
TAZ domain | 0 | Direct |
Flavoproteins | 0 | Direct |
Subtilisin-like | 0 | Direct |
Translation proteins SH3-like domain | 0 | Direct |
Ribonuclease PH domain 2-like | 0 | Direct |
GroES-like | 0 | Direct |
Pepsin inhibitor-3 | 0 | Direct |
Inhibitor of apoptosis (IAP) repeat | 0 | Direct |
Small-conductance potassium channel | 0 | Direct |
Nucleotide cyclase | 0 | Direct |
HSP20-like chaperones | 0 | Direct |
Hypothetical protein c14orf129, hspc210 | 0 | Direct |
CBS-domain pair | 0 | Direct |
Integrin alpha N-terminal domain | 0 | Direct |
E2F-DP heterodimerization region | 0 | Direct |
lambda repressor-like DNA-binding domains | 0 | Direct |
2Fe-2S ferredoxin-like | 0 | Direct |
HIT/MYND zinc finger-like | 0 | Direct |
BPTI-like | 0 | Direct |
RmlC-like cupins | 0 | Direct |
HSP40/DnaJ peptide-binding domain | 0 | Direct |
Cdc48 domain 2-like | 0 | Direct |
Nucleotide-diphospho-sugar transferases | 0 | Direct |
Thyroglobulin type-1 domain | 0 | Direct |
Phosphoglucomutase, C-terminal domain | 0 | Direct |
Spermadhesin, CUB domain | 0 | Direct |
Glycoside hydrolase/deacetylase | 0 | Direct |
PABC (PABP) domain | 0 | Direct |
Heme-dependent peroxidases | 0 | Direct |
Transcription factor IIA (TFIIA), alpha-helical domain | 0 | Direct |
SAICAR synthase-like | 0 | Direct |
L domain-like | 0 | Direct |
Rhomboid-like | 0 | Direct |
Restriction endonuclease-like | 0 | Direct |
Guanido kinase N-terminal domain | 0 | Direct |
Chitinase insertion domain | 0 | Direct |
Clathrin adaptor appendage domain | 0 | Direct |
Ran binding protein zinc finger-like | 0 | Direct |
Cu,Zn superoxide dismutase-like | 0 | Direct |
Adenine nucleotide alpha hydrolases-like | 0 | Direct |
Radical SAM enzymes | 0 | Direct |
Ribosomal protein L10-like | 0 | Direct |
S-adenosyl-L-methionine-dependent methyltransferases | 0 | Direct |
Glycolipid transfer protein, GLTP | 0 | Direct |
Hemopexin-like domain | 0 | Direct |
Mob1/phocein | 0 | Direct |
Clc chloride channel | 0 | Direct |
DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
Tubulin C-terminal domain-like | 0 | Direct |
Smc hinge domain | 0 | Direct |
UBC-like | 0 | Direct |
SpoIIaa-like | 0 | Direct |
Serine protease inhibitors | 0 | Direct |
PYP-like sensor domain (PAS domain) | 0 | Direct |
Tetraspanin | 0 | Direct |
Bacterial exopeptidase dimerisation domain | 0 | Direct |
Frizzled cysteine-rich domain | 0 | Direct |
Periplasmic binding protein-like II | 0 | Direct |
Chaperone J-domain | 0 | Direct |
Caspase-like | 0 | Direct |
Ribulose-phoshate binding barrel | 0 | Direct |
Annexin | 0 | Direct |
HCP-like | 0 | Direct |
MIT domain | 0 | Direct |
Class II aaRS ABD-related | 0 | Direct |
PEBP-like | 0 | Direct |
Concanavalin A-like lectins/glucanases | 0 | Direct |
Putative DNA-binding domain | 0 | Direct |
SAP domain | 0 | Direct |
WWE domain | 0 | Direct |
PDZ domain-like | 0 | Direct |
EB1 dimerisation domain-like | 0 | Direct |
Ammonium transporter | 0 | Direct |
Zinc beta-ribbon | 0 | Direct |
Pseudouridine synthase | 0 | Direct |
Seven-hairpin glycosidases | 0 | Direct |
Translation proteins | 0 | Direct |
Myosin rod fragments | 0 | Direct |
PRTase-like | 0 | Direct |
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | Direct |
Kix domain of CBP (creb binding protein) | 0 | Direct |
Subdomain of clathrin and coatomer appendage domain | 0 | Direct |
ABC transporter transmembrane region | 0 | Direct |
Sm-like ribonucleoproteins | 0 | Direct |
SNARE fusion complex | 0 | Direct |
HMG-box | 0 | Direct |
Pentein | 0 | Direct |
FAD-dependent thiol oxidase | 0 | Direct |
FAD-binding/transporter-associated domain-like | 0 | Direct |
Hedgehog/intein (Hint) domain | 0 | Direct |
GHMP Kinase, C-terminal domain | 0 | Direct |
Ankyrin repeat | 0 | Direct |
PurM C-terminal domain-like | 0 | Direct |
Ribosomal protein S10 | 0 | Direct |
Acyl-CoA dehydrogenase NM domain-like | 0 | Direct |
Intermediate filament protein, coiled coil region | 0 | Direct |
Molybdenum cofactor-binding domain | 0 | Direct |
C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
GroEL apical domain-like | 0 | Direct |
Domain of poly(ADP-ribose) polymerase | 0 | Direct |
PX domain | 0 | Direct |
Actin-crosslinking proteins | 0 | Direct |
Second domain of FERM | 0 | Direct |
Fibrinogen C-terminal domain-like | 0 | Direct |
Glutathione synthetase ATP-binding domain-like | 0 | Direct |
GYF domain | 0 | Direct |
Composite domain of metallo-dependent hydrolases | 0 | Direct |
DNase I-like | 0 | Direct |
Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | Direct |
Growth factor receptor domain | 0 | Direct |
Acid phosphatase/Vanadium-dependent haloperoxidase | 0 | Direct |
PEP carboxykinase-like | 0 | Direct |
TGS-like | 0 | Direct |
Diaminopimelate epimerase-like | 0 | Direct |
Troponin coil-coiled subunits | 0 | Direct |
MOSC N-terminal domain-like | 0 | Direct |
FF domain | 0 | Direct |
Ribokinase-like | 0 | Direct |
Polo-box domain | 0 | Direct |
ThrRS/AlaRS common domain | 0 | Direct |
Protease propeptides/inhibitors | 0 | Direct |
FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | Direct |
BRCT domain | 0 | Direct |
CO dehydrogenase ISP C-domain like | 0 | Direct |
DNA clamp | 0 | Direct |
SET domain | 0 | Direct |
Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | Direct |
Translational machinery components | 0 | Direct |
Invertebrate chitin-binding proteins | 0 | Direct |
Rudiment single hybrid motif | 0 | Direct |
L-aspartase-like | 0 | Direct |
Hect, E3 ligase catalytic domain | 0 | Direct |
DNA ligase/mRNA capping enzyme, catalytic domain | 0 | Direct |
Outer arm dynein light chain 1 | 0 | Direct |
ValRS/IleRS/LeuRS editing domain | 0 | Direct |
Six-hairpin glycosidases | 0 | Direct |
CoA-dependent acyltransferases | 0 | Direct |
Glutamine synthetase, N-terminal domain | 0 | Direct |
Elafin-like | 0 | Direct |
Cadherin-like | 0 | Direct |
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | Direct |
Metallo-dependent hydrolases | 0 | Direct |
Nucleotide-binding domain | 0 | Direct |
Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | Direct |
NagB/RpiA/CoA transferase-like | 0 | Direct |
KA1-like | 0 | Direct |
ARM repeat | 0.08004 | Inherited |
RNA-binding domain, RBD | 0.2112 | Inherited |
PapD-like | 0.2487 | Inherited |
Nicotinic receptor ligand binding domain-like | 0.2761 | Inherited |
Voltage-gated potassium channels | 0.3243 | Inherited |
Neurotransmitter-gated ion-channel transmembrane pore | 0.329 | Inherited |
Ubiquitin-like | 0.3699 | Inherited |
Metallo-dependent phosphatases | 0.4365 | Inherited |
FYVE/PHD zinc finger | 0.5315 | Inherited |
EF-hand | 0.625 | Inherited |
WD40 repeat-like | 0.6668 | Inherited |
TPR-like | 0.6882 | Inherited |
GTPase activation domain, GAP | 0.7397 | Inherited |
P-loop containing nucleoside triphosphate hydrolases | 0.7413 | Inherited |
Saposin | 0.7903 | Inherited |
(Phosphotyrosine protein) phosphatases II | 0.8216 | Inherited |
"Winged helix" DNA-binding domain | 0.889 | Inherited |
RING/U-box | 0.9098 | Inherited |
Lamin A/C globular tail domain | 0.9465 | Inherited |
PLP-dependent transferases | 0.9539 | Inherited |
Protein kinase-like (PK-like) | 1 | Inherited |
SH2 domain | 1 | Inherited |
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Family(show details)
Family domains annotated to this WP term (Not in SDWP)
Highlighted in gray are those with FDR_all>0.001
SCOP term | FDR (all) | Annotation (direct or inherited) |
Ribosomal protein S10 | 0 | DIRECT |
Transducin (heterotrimeric G protein), gamma chain | 0 | DIRECT |
RNA-polymerase beta-prime | 0 | DIRECT |
Ubiquitin carboxyl-terminal hydrolase UCH-L | 0 | DIRECT |
Sec7 domain | 0 | DIRECT |
Carbonic anhydrase | 0 | DIRECT |
XPF/Rad1/Mus81 nuclease | 0 | DIRECT |
ZZ domain | 0 | DIRECT |
Serum paraoxonase/arylesterase 1, PON1 | 0 | DIRECT |
Pepsin-like | 0 | DIRECT |
L domain | 0 | DIRECT |
RING finger domain, C3HC4 | 0 | DIRECT |
Armadillo repeat | 0 | DIRECT |
Clc chloride channel | 0 | DIRECT |
Troponin I | 0 | DIRECT |
Phoshatidylinositol transfer protein, PITP | 0 | DIRECT |
Phosphoglucomutase, first 3 domains | 0 | DIRECT |
FabD-like | 0 | DIRECT |
MutT-like | 0 | DIRECT |
Matrix metalloproteases, catalytic domain | 0 | DIRECT |
COMT-like | 0 | DIRECT |
Roadblock/LC7 domain | 0 | DIRECT |
Thiolase-related | 0 | DIRECT |
Type II chitinase | 0 | DIRECT |
Aminomethyltransferase folate-binding domain | 0 | DIRECT |
FMN-linked oxidoreductases | 0 | DIRECT |
Ribonuclease PH domain 1-like | 0 | DIRECT |
N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
Sir2 family of transcriptional regulators | 0 | DIRECT |
NADPH-cytochrome p450 reductase-like | 0 | DIRECT |
FAD/NAD-linked reductases, N-terminal and central domains | 0 | DIRECT |
CCCH zinc finger | 0 | DIRECT |
POU-specific domain | 0 | DIRECT |
Calpain large subunit, middle domain (domain III) | 0 | DIRECT |
Fibronectin type III | 0 | DIRECT |
Frizzled cysteine-rich domain | 0 | DIRECT |
Guanido kinase catalytic domain | 0 | DIRECT |
alpha-mannosidase | 0 | DIRECT |
EF-G/eEF-2 domains III and V | 0 | DIRECT |
YihX-like | 0 | DIRECT |
Ribonuclease PH domain 2-like | 0 | DIRECT |
Domain of poly(ADP-ribose) polymerase | 0 | DIRECT |
Patatin | 0 | DIRECT |
NTF2-like | 0 | DIRECT |
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
Protein prenyltransferases | 0 | DIRECT |
Kix domain of CBP (creb binding protein) | 0 | DIRECT |
C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
Paired domain | 0 | DIRECT |
VHS domain | 0 | DIRECT |
GYF domain | 0 | DIRECT |
AMPK-beta glycogen binding domain-like | 0 | DIRECT |
U-box | 0 | DIRECT |
D-aminoacid oxidase-like | 0 | DIRECT |
ALDH-like | 0 | DIRECT |
Proprotein convertase P-domain | 0 | DIRECT |
C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
H-NOX domain | 0 | DIRECT |
NagD-like | 0 | DIRECT |
ValRS/IleRS/LeuRS editing domain | 0 | DIRECT |
Protein kinase cysteine-rich domain (cys2, phorbol-binding domain) | 0 | DIRECT |
Hydantoinase (dihydropyrimidinase), catalytic domain | 0 | DIRECT |
beta-Lactamase/D-ala carboxypeptidase | 0 | DIRECT |
Elongation factors | 0 | DIRECT |
Mob1/phocein | 0 | DIRECT |
Pumilio repeat | 0 | DIRECT |
Caspase catalytic domain | 0 | DIRECT |
alpha-catenin/vinculin | 0 | DIRECT |
Band 7/SPFH domain | 0 | DIRECT |
Serpins | 0 | DIRECT |
Hexokinase | 0 | DIRECT |
Adenylyl and guanylyl cyclase catalytic domain | 0 | DIRECT |
Oxysterol-binding protein | 0 | DIRECT |
DPP6 catalytic domain-like | 0 | DIRECT |
Glutamine synthetase, N-terminal domain | 0 | DIRECT |
5' to 3' exonuclease catalytic domain | 0 | DIRECT |
Cofilin-like | 0 | DIRECT |
Ribonuclease H | 0 | DIRECT |
Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
Hypothetical protein c14orf129, hspc210 | 0 | DIRECT |
CO dehydrogenase flavoprotein N-terminal domain-like | 0 | DIRECT |
Gamma-glutamyltranspeptidase-like | 0 | DIRECT |
LysM domain | 0 | DIRECT |
Ypt/Rab-GAP domain of gyp1p | 0 | DIRECT |
Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain | 0 | DIRECT |
FYVE, a phosphatidylinositol-3-phosphate binding domain | 0 | DIRECT |
Mo25 protein | 0 | DIRECT |
Chitinase insertion domain | 0 | DIRECT |
Leukotriene A4 hydrolase N-terminal domain | 0 | DIRECT |
F-box domain | 0 | DIRECT |
Classic zinc finger, C2H2 | 0 | DIRECT |
Ran binding protein zinc finger-like | 0 | DIRECT |
FAD-linked reductases, N-terminal domain | 0 | DIRECT |
Brix domain | 0 | DIRECT |
Mitochondrial carrier | 0 | DIRECT |
NHL repeat | 0 | DIRECT |
Laminin-type module | 0 | DIRECT |
Proteasome subunits | 0 | DIRECT |
Group II chaperonin (CCT, TRIC), ATPase domain | 0 | DIRECT |
Group II chaperonin (CCT, TRIC), apical domain | 0 | DIRECT |
WW domain | 0 | DIRECT |
E2F dimerization segment | 0 | DIRECT |
Transcriptional factor domain | 0 | DIRECT |
Inositol monophosphatase/fructose-1,6-bisphosphatase-like | 0 | DIRECT |
Ribosomal protein L18 and S11 | 0 | DIRECT |
Dual specificity phosphatase-like | 0 | DIRECT |
SAM (sterile alpha motif) domain | 0 | DIRECT |
Histone lysine methyltransferases | 0 | DIRECT |
Tetramerization domain of potassium channels | 0 | DIRECT |
Bromodomain | 0 | DIRECT |
Catalytic, N-terminal domain of histone methyltransferase Dot1l | 0 | DIRECT |
Thyroglobulin type-1 domain | 0 | DIRECT |
HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
Ricin B-like | 0 | DIRECT |
Ribokinase-like | 0 | DIRECT |
Cysteine-rich DNA binding domain, (DM domain) | 0 | DIRECT |
Poly(ADP-ribose) polymerase, C-terminal domain | 0 | DIRECT |
Actin/HSP70 | 0 | DIRECT |
CBS-domain pair | 0 | DIRECT |
Integrin A (or I) domain | 0 | DIRECT |
Amidase signature (AS) enzymes | 0 | DIRECT |
Fungal lipases | 0 | DIRECT |
HSP90 C-terminal domain | 0 | DIRECT |
Intermediate filament protein, coiled coil region | 0 | DIRECT |
Clathrin coat assembly domain | 0 | DIRECT |
Cytochrome b5 | 0 | DIRECT |
SMAD MH1 domain | 0 | DIRECT |
CalX-beta domain | 0 | DIRECT |
Plexin repeat | 0 | DIRECT |
MIF-related | 0 | DIRECT |
Transcription factor IIA (TFIIA), alpha-helical domain | 0 | DIRECT |
BTB/POZ domain | 0 | DIRECT |
Globins | 0 | DIRECT |
Cdc48 N-terminal domain-like | 0 | DIRECT |
Hsp90 middle domain | 0 | DIRECT |
Class I alpha-1;2-mannosidase, catalytic domain | 0 | DIRECT |
UBX domain | 0 | DIRECT |
GAS2 domain | 0 | DIRECT |
Lactate & malate dehydrogenases, C-terminal domain | 0 | DIRECT |
Gastric lipase | 0 | DIRECT |
Bacterial dinuclear zinc exopeptidases | 0 | DIRECT |
Aldo-keto reductases (NADP) | 0 | DIRECT |
CRAL/TRIO domain | 0 | DIRECT |
Ganglioside M2 (gm2) activator | 0 | DIRECT |
UBC-related | 0 | DIRECT |
Calcium ATPase, transduction domain A | 0 | DIRECT |
Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | DIRECT |
Spectrin repeat | 0 | DIRECT |
PurM C-terminal domain-like | 0 | DIRECT |
Cytidylyltransferase | 0 | DIRECT |
RecA protein-like (ATPase-domain) | 0 | DIRECT |
Second domain of FERM | 0 | DIRECT |
CoA-binding domain | 0 | DIRECT |
Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta | 0 | DIRECT |
NOL1/NOP2/sun | 0 | DIRECT |
PEP carboxykinase N-terminal domain | 0 | DIRECT |
6-phosphogluconate dehydrogenase-like, N-terminal domain | 0 | DIRECT |
Transforming growth factor (TGF)-beta | 0 | DIRECT |
IF2B-like | 0 | DIRECT |
Cytoplasmic domain of inward rectifier potassium channel | 0 | DIRECT |
Spermadhesin, CUB domain | 0 | DIRECT |
Profilin (actin-binding protein) | 0 | DIRECT |
LEM domain | 0 | DIRECT |
Choline kinase | 0 | DIRECT |
ATI-like | 0 | DIRECT |
DEP domain | 0 | DIRECT |
Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain | 0 | DIRECT |
Multidomain sulfurtransferase (rhodanese) | 0 | DIRECT |
Citrate synthase | 0 | DIRECT |
Pancreatic carboxypeptidases | 0 | DIRECT |
Phosphatidylethanolamine binding protein | 0 | DIRECT |
DBL homology domain (DH-domain) | 0 | DIRECT |
Meta-cation ATPase, catalytic domain P | 0 | DIRECT |
BAR domain | 0 | DIRECT |
Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
Histone deacetylase, HDAC | 0 | DIRECT |
Deoxycytidylate deaminase-like | 0 | DIRECT |
RhoGDI-like | 0 | DIRECT |
Cap-Gly domain | 0 | DIRECT |
CoA transferase alpha subunit-like | 0 | DIRECT |
Phosphoribosyltransferases (PRTases) | 0 | DIRECT |
Reductases | 0 | DIRECT |
Retrovirus zinc finger-like domains | 0 | DIRECT |
beta 1,4 galactosyltransferase (b4GalT1) | 0 | DIRECT |
Cystathionine synthase-like | 0 | DIRECT |
Small Kunitz-type inhibitors & BPTI-like toxins | 0 | DIRECT |
Hemocyanin middle domain | 0 | DIRECT |
I set domains | 0 | DIRECT |
Hedgehog C-terminal (Hog) autoprocessing domain | 0 | DIRECT |
beta-sandwich domain of Sec23/24 | 0 | DIRECT |
Clathrin adaptor core protein | 0 | DIRECT |
Vertebrate phospholipase A2 | 0 | DIRECT |
TBP-associated factors, TAFs | 0 | DIRECT |
Alcohol dehydrogenase-like, N-terminal domain | 0 | DIRECT |
CUT domain | 0 | DIRECT |
Ferredoxin domains from multidomain proteins | 0 | DIRECT |
Papain-like | 0 | DIRECT |
Sec63 N-terminal domain | 0 | DIRECT |
DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
NLI interacting factor-like phosphatase | 0 | DIRECT |
Ferredoxin reductase FAD-binding domain-like | 0 | DIRECT |
SH3-domain | 0 | DIRECT |
Nitrogenase iron protein-like | 0 | DIRECT |
SWIRM domain | 0 | DIRECT |
Sema domain | 0 | DIRECT |
Translation initiation factor eIF4e | 0 | DIRECT |
Tetraspanin | 0 | DIRECT |
Calpain large subunit, catalytic domain (domain II) | 0 | DIRECT |
PUA domain | 0 | DIRECT |
YicI catalytic domain-like | 0 | DIRECT |
Nucleotide and nucleoside kinases | 0 | DIRECT |
alpha-Amylases, C-terminal beta-sheet domain | 0 | DIRECT |
TatD Mg-dependent DNase-like | 0 | DIRECT |
DNA replication initiator (cdc21/cdc54) N-terminal domain | 0 | DIRECT |
Doublecortin (DC) | 0 | DIRECT |
Cell cycle transcription factor e2f-dp | 0 | DIRECT |
DNA repair protein MutS, domain III | 0 | DIRECT |
UBA domain | 0 | DIRECT |
Trehalase-like | 0 | DIRECT |
Aquaporin-like | 0 | DIRECT |
RUN domain | 0 | DIRECT |
Pseudouridine synthase I TruA | 0 | DIRECT |
RNA methyltransferase FtsJ | 0 | DIRECT |
Quinoprotein alcohol dehydrogenase-like | 0 | DIRECT |
N-acetylglucosaminyltransferase I | 0 | DIRECT |
PLC-like (P variant) | 0 | DIRECT |
Carboxypeptidase regulatory domain | 0 | DIRECT |
Myotubularin-like phosphatases | 0 | DIRECT |
acyl-CoA oxidase C-terminal domains | 0 | DIRECT |
CRAL/TRIO N-terminal domain | 0 | DIRECT |
4HBT-like | 0 | DIRECT |
Rap/Ran-GAP | 0 | DIRECT |
Polo-box duplicated region | 0 | DIRECT |
Integrin domains | 0 | DIRECT |
PDI-like | 0 | DIRECT |
RNA editing terminal uridyl transferase 2, RET2, domain 2 | 0 | DIRECT |
Cation efflux protein transmembrane domain-like | 0 | DIRECT |
HAT/Suf repeat | 0 | DIRECT |
B-box zinc-binding domain | 0 | DIRECT |
Regulator of chromosome condensation RCC1 | 0 | DIRECT |
Surp module (SWAP domain) | 0 | DIRECT |
GABA-aminotransferase-like | 0 | DIRECT |
Ribosomal protein S18 | 0 | DIRECT |
Phosphate binding protein-like | 0 | DIRECT |
Serine carboxypeptidase-like | 0 | DIRECT |
Tudor domain | 0 | DIRECT |
Linker histone H1/H5 | 0 | DIRECT |
PhzC/PhzF-like | 0 | DIRECT |
Smc hinge domain | 0 | DIRECT |
TAZ domain | 0 | DIRECT |
SAP domain | 0 | DIRECT |
Fibrinogen C-terminal domain-like | 0 | DIRECT |
Arylsulfatase | 0 | DIRECT |
SAND domain | 0 | DIRECT |
p120GAP domain-like | 0 | DIRECT |
Nucleoside diphosphate kinase, NDK | 0 | DIRECT |
HD domain | 0 | DIRECT |
Reprolysin-like | 0 | DIRECT |
SNARE fusion complex | 0 | DIRECT |
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
L-arabinose binding protein-like | 0 | DIRECT |
Phosphotyrosine-binding domain (PTB) | 0 | DIRECT |
WGR domain | 0 | DIRECT |
Pyk2-associated protein beta ARF-GAP domain | 0 | DIRECT |
Calcium ATPase, transmembrane domain M | 0 | DIRECT |
MIF4G domain-like | 0 | DIRECT |
Glycogenin | 0 | DIRECT |
AraD-like aldolase/epimerase | 0 | DIRECT |
Glycolipid transfer protein, GLTP | 0 | DIRECT |
Guanido kinase N-terminal domain | 0 | DIRECT |
SPRY domain | 0 | DIRECT |
Pepsin inhibitor-3 | 0 | DIRECT |
L30e/L7ae ribosomal proteins | 0 | DIRECT |
Eps15 homology domain (EH domain) | 0 | DIRECT |
Osmotin, thaumatin-like protein | 0 | DIRECT |
Cdc48 domain 2-like | 0 | DIRECT |
Heat shock protein 90, HSP90, N-terminal domain | 0 | DIRECT |
Histidine acid phosphatase | 0 | DIRECT |
CAT-like | 0 | DIRECT |
Tubulin, GTPase domain | 0 | DIRECT |
Hydantoinase (dihydropyrimidinase) | 0 | DIRECT |
Eukaryotic type KH-domain (KH-domain type I) | 0 | DIRECT |
EF-hand modules in multidomain proteins | 0 | DIRECT |
Bacterial lipase | 0 | DIRECT |
Transcription factor IIA (TFIIA), beta-barrel domain | 0 | DIRECT |
Ras GEF | 0 | DIRECT |
Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains | 0 | DIRECT |
Fatty acid binding protein-like | 0 | DIRECT |
Growth factor receptor domain | 0 | DIRECT |
Astacin | 0 | DIRECT |
Neurotransmitter-gated ion-channel transmembrane pore | 0 | DIRECT |
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | DIRECT |
Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain | 0 | DIRECT |
FAD-dependent thiol oxidase | 0 | DIRECT |
DEATH domain, DD | 0 | DIRECT |
Annexin | 0 | DIRECT |
Class I aldolase | 0 | DIRECT |
Erythroid transcription factor GATA-1 | 0 | DIRECT |
Polypeptide N-acetylgalactosaminyltransferase 1, N-terminal domain | 0 | DIRECT |
Ankyrin repeat | 0 | DIRECT |
EGF-type module | 0 | DIRECT |
Cadherin | 0 | DIRECT |
Ephrin ectodomain | 0 | DIRECT |
N-type ATP pyrophosphatases | 0 | DIRECT |
Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | DIRECT |
Zn-finger domain of Sec23/24 | 0 | DIRECT |
Sec63 C-terminal domain-like | 0 | DIRECT |
Filamin repeat (rod domain) | 0 | DIRECT |
Ribosomal protein L1 | 0 | DIRECT |
D-aminoacid oxidase, N-terminal domain | 0 | DIRECT |
Peptidylglycine alpha-hydroxylating monooxygenase, PHM | 0 | DIRECT |
Prefoldin | 0 | DIRECT |
F1F0 ATP synthase subunit C | 0 | DIRECT |
MOSC N-terminal domain-like | 0 | DIRECT |
beta-glycanases | 0 | DIRECT |
Kelch motif | 0 | DIRECT |
Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
Class II glutamine amidotransferases | 0 | DIRECT |
Family 19 glycosidase | 0 | DIRECT |
Rhomboid-like | 0 | DIRECT |
HEAT repeat | 0 | DIRECT |
PP2C-like | 0 | DIRECT |
UDPGT-like | 0 | DIRECT |
Metal cation-transporting ATPase, ATP-binding domain N | 0 | DIRECT |
PhyH-like | 0 | DIRECT |
Formin homology 2 domain (FH2 domain) | 0 | DIRECT |
Neurolysin-like | 0 | DIRECT |
Ubiquitin-related | 0 | DIRECT |
NADPH-cytochrome p450 reductase FAD-binding domain-like | 0 | DIRECT |
Nop domain | 0 | DIRECT |
Pyridoxal-dependent decarboxylase | 0 | DIRECT |
Sec1/munc18-like (SM) proteins | 0 | DIRECT |
PaaI/YdiI-like | 0 | DIRECT |
5' to 3' exonuclease, C-terminal subdomain | 0 | DIRECT |
Hect, E3 ligase catalytic domain | 0 | DIRECT |
Tubulin, C-terminal domain | 0 | DIRECT |
Choline/Carnitine O-acyltransferase | 0 | DIRECT |
PABC (PABP) domain | 0 | DIRECT |
Inositol polyphosphate 5-phosphatase (IPP5) | 0 | DIRECT |
FCH domain | 0 | DIRECT |
Bactericidal permeability-increasing protein, BPI | 0 | DIRECT |
RIO1-like kinases | 0 | DIRECT |
PDZ domain | 0 | DIRECT |
alpha-mannosidase, domain 2 | 0 | DIRECT |
Sterol carrier protein, SCP | 0 | DIRECT |
Branched-chain alpha-keto acid dehydrogenase Pyr module | 0 | DIRECT |
Ammonium transporter | 0 | DIRECT |
Elafin-like | 0 | DIRECT |
Biotinyl/lipoyl-carrier proteins and domains | 0 | DIRECT |
14-3-3 protein | 0 | DIRECT |
AN1-like Zinc finger | 0 | DIRECT |
Ngr ectodomain-like | 0 | DIRECT |
Helical domain of Sec23/24 | 0 | DIRECT |
Cold shock DNA-binding domain-like | 0 | DIRECT |
N-acetyl transferase, NAT | 0 | DIRECT |
Aminoacid dehydrogenase-like, C-terminal domain | 0 | DIRECT |
Medium chain acyl-CoA dehydrogenase-like, C-terminal domain | 0 | DIRECT |
Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | DIRECT |
Succinyl-CoA synthetase domains | 0 | DIRECT |
Internalin LRR domain | 0 | DIRECT |
Ubiquitin activating enzymes (UBA) | 0 | DIRECT |
Synaptotagmin-like (S variant) | 0 | DIRECT |
Multidrug efflux transporter AcrB transmembrane domain | 0 | DIRECT |
MIT domain | 0 | DIRECT |
Formate/glycerate dehydrogenases, NAD-domain | 0 | DIRECT |
EB1 dimerisation domain-like | 0 | DIRECT |
GAPDH-like | 0 | DIRECT |
Acyl-CoA binding protein | 0 | DIRECT |
1,3-glucuronyltransferase | 0 | DIRECT |
Chaperone J-domain | 0 | DIRECT |
Diap1 N-terninal region-like | 0 | DIRECT |
Gelsolin-like | 0 | DIRECT |
GHMP Kinase, N-terminal domain | 0 | DIRECT |
Class I glutamine amidotransferases (GAT) | 0 | DIRECT |
Galectin (animal S-lectin) | 0 | DIRECT |
HMG-box | 0 | DIRECT |
Purple acid phosphatase-like | 0 | DIRECT |
Phoshoinositide 3-kinase (PI3K) helical domain | 0 | DIRECT |
Molybdenum cofactor-binding domain | 0 | DIRECT |
AlkB-like | 0 | DIRECT |
eIF1-like | 0 | DIRECT |
PX domain | 0 | DIRECT |
PDEase | 0 | DIRECT |
ATP-dependent protease Lon (La), catalytic domain | 0 | DIRECT |
Trunk domain of Sec23/24 | 0 | DIRECT |
T-box | 0 | DIRECT |
UDP-glucose pyrophosphorylase | 0 | DIRECT |
Biotin dependent carboxylase carboxyltransferase domain | 0 | DIRECT |
Regulator of G-protein signaling, RGS | 0 | DIRECT |
Ras-binding domain, RBD | 0 | DIRECT |
Acyl-CoA thioesterase | 0 | DIRECT |
Myeloperoxidase-like | 0 | DIRECT |
CO dehydrogenase ISP C-domain like | 0 | DIRECT |
Acireductone dioxygenase | 0 | DIRECT |
Alcohol dehydrogenase-like, C-terminal domain | 0 | DIRECT |
Hermes transposase-like | 0 | DIRECT |
LacY-like proton/sugar symporter | 0 | DIRECT |
Lesion bypass DNA polymerase (Y-family), catalytic domain | 0 | DIRECT |
STAR domain | 0 | DIRECT |
ABC transporter transmembrane region | 0 | DIRECT |
Myosin rod fragments | 0 | DIRECT |
Cyclophilin (peptidylprolyl isomerase) | 0 | DIRECT |
Pancreatic carboxypeptidase, activation domain | 0 | DIRECT |
Blood coagulation inhibitor (disintegrin) | 0 | DIRECT |
Carboxylesterase | 0 | DIRECT |
HSP20 | 0 | DIRECT |
alpha-mannosidase, C-terminal domain | 0 | DIRECT |
RNA-polymerase beta | 0 | DIRECT |
Creatinase/aminopeptidase | 0 | DIRECT |
Phoshoinositide 3-kinase (PI3K), catalytic domain | 0 | DIRECT |
LIM domain | 0 | DIRECT |
Tropomyosin | 0 | DIRECT |
Arylamine N-methyltransferase | 0 | DIRECT |
Skp1 dimerisation domain-like | 0 | DIRECT |
PR-1-like | 0 | DIRECT |
Zf-UBP | 0 | DIRECT |
Pleckstrin-homology domain (PH domain) | 0 | DIRECT |
FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | DIRECT |
Purple acid phosphatase, N-terminal domain | 0 | DIRECT |
Sm motif of small nuclear ribonucleoproteins, SNRNP | 0 | DIRECT |
S-adenosylmethionine synthetase | 0 | DIRECT |
Hemopexin-like domain | 0 | DIRECT |
Branched-chain alpha-keto acid dehydrogenase PP module | 0 | DIRECT |
LDL receptor-like module | 0 | DIRECT |
Inhibitor of apoptosis (IAP) repeat | 0 | DIRECT |
Transducin (alpha subunit), insertion domain | 0 | DIRECT |
Aminomethyltransferase beta-barrel domain | 0 | DIRECT |
HCDH C-domain-like | 0 | DIRECT |
28-residue LRR | 0 | DIRECT |
FtsH protease domain-like | 0 | DIRECT |
beta-CASP RNA-metabolising hydrolases | 0 | DIRECT |
SWIB/MDM2 domain | 0 | DIRECT |
MFPT repeat | 0 | DIRECT |
Subtilases | 0 | DIRECT |
BC N-terminal domain-like | 0 | DIRECT |
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
Glycerol-3-phosphate transporter | 0 | DIRECT |
MIR domain | 0 | DIRECT |
Small-conductance potassium channel | 0 | DIRECT |
Cation efflux protein cytoplasmic domain-like | 0 | DIRECT |
Arfaptin, Rac-binding fragment | 0 | DIRECT |
Lipovitellin-phosvitin complex, superhelical domain | 0 | DIRECT |
Myb/SANT domain | 0 | DIRECT |
Third domain of FERM | 0 | DIRECT |
BC C-terminal domain-like | 0 | DIRECT |
Smr domain | 0 | DIRECT |
Supernatant protein factor (SPF), C-terminal domain | 0 | DIRECT |
YbiA-like | 0 | DIRECT |
Glycerol kinase | 0 | DIRECT |
PurM N-terminal domain-like | 0 | DIRECT |
L-aminoacid/polyamine oxidase | 0 | DIRECT |
HLH, helix-loop-helix DNA-binding domain | 0 | DIRECT |
Rv2717c-like | 0 | DIRECT |
BEACH domain | 0 | DIRECT |
BC ATP-binding domain-like | 0 | DIRECT |
DPP6 N-terminal domain-like | 0 | DIRECT |
SMAD domain | 0 | DIRECT |
Acylamino-acid-releasing enzyme, C-terminal donain | 0 | DIRECT |
BolA-like | 0 | DIRECT |
Glycerophosphoryl diester phosphodiesterase | 0 | DIRECT |
BSD domain | 0 | DIRECT |
WWE domain | 0 | DIRECT |
Dimeric isocitrate & isopropylmalate dehydrogenases | 0 | DIRECT |
Methionine aminopeptidase, insert domain | 0 | DIRECT |
Anticodon-binding domain | 0 | DIRECT |
Tim10/DDP | 0 | DIRECT |
Chromo domain | 0 | DIRECT |
FF domain | 0 | DIRECT |
t-snare proteins | 0 | DIRECT |
Glutamine synthetase catalytic domain | 0 | DIRECT |
Anticodon-binding domain of Class II aaRS | 0 | DIRECT |
FHA domain | 0 | DIRECT |
Acyl-carrier protein (ACP) | 0 | DIRECT |
Arginine methyltransferase | 0 | DIRECT |
Amylase, catalytic domain | 0 | DIRECT |
PEP carboxykinase C-terminal domain | 0 | DIRECT |
First domain of FERM | 0 | DIRECT |
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | DIRECT |
Hormone receptor domain | 0 | DIRECT |
ARID domain | 0 | DIRECT |
CO dehydrogenase molybdoprotein N-domain-like | 0 | DIRECT |
La domain | 0 | DIRECT |
Adenain-like | 0 | DIRECT |
Heme-dependent catalases | 0 | DIRECT |
Epoxide hydrolase | 0 | DIRECT |
Laminin G-like module | 0 | DIRECT |
Calmodulin-like | 0 | DIRECT |
2Fe-2S ferredoxin domains from multidomain proteins | 0 | DIRECT |
LDH N-terminal domain-like | 0 | DIRECT |
Autophagin-like | 0 | DIRECT |
Inositol polyphosphate kinase (IPK) | 0 | DIRECT |
YWTD domain | 0 | DIRECT |
Leukotriene A4 hydrolase catalytic domain | 0 | DIRECT |
cAMP-binding domain | 0 | DIRECT |
Cu,Zn superoxide dismutase-like | 0 | DIRECT |
Complement control module/SCR domain | 0 | DIRECT |
Cell cycle control phosphatase, catalytic domain | 0 | DIRECT |
ets domain | 0 | DIRECT |
Group II chaperonin (CCT, TRIC), intermediate domain | 0 | DIRECT |
Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
Glutaminase | 0 | DIRECT |
Proton glutamate symport protein | 0 | DIRECT |
Mammalian PLC | 0 | DIRECT |
Kinase associated domain 1, KA1 | 0 | DIRECT |
Crotonase-like | 0 | DIRECT |
Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain | 0 | DIRECT |
Translational machinery components | 0 | DIRECT |
Bacterial exopeptidase dimerisation domain | 0 | DIRECT |
acyl-CoA oxidase N-terminal domains | 0 | DIRECT |
Calponin-homology domain, CH-domain | 0 | DIRECT |
Single strand DNA-binding domain, SSB | 0 | DIRECT |
Canonical RBD | 0.2513 | INHERITED FROM: sterile F1 || brood size variant |
MSP-like | 0.2803 | INHERITED FROM: sterile progeny |
Nicotinic receptor ligand binding domain-like | 0.2803 | INHERITED FROM: synaptic transmission variant || coelomic system physiology variant || coelomocyte uptake defective || transmission of nerve impulse variant || nervous system physiology variant || coelomocyte physiology variant |
Voltage-gated potassium channels | 0.3239 | INHERITED FROM: muscle cell activity variant |
Tandem AAA-ATPase domain | 0.3341 | INHERITED FROM: male fertility reduced || male sterile || male fertility variant |
G proteins | 0.4101 | INHERITED FROM: synaptic transmission variant || postsynaptic region physiology variant || nervous system physiology variant |
Homeodomain | 0.6761 | INHERITED FROM: nervous system physiology variant |
BCR-homology GTPase activation domain (BH-domain) | 0.7908 | INHERITED FROM: muscle cell attachment variant || muscle system physiology variant |
WD40-repeat | 0.8104 | INHERITED FROM: brood size variant || reduced brood size |
Cyclin | 0.8382 | INHERITED FROM: male gonad development variant |
Protein kinases, catalytic subunit | 0.9024 | INHERITED FROM: muscle system physiology variant || body muscle dystrophy || muscle cell physiology variant |
Lamin A/C globular tail domain | 0.9522 | INHERITED FROM: muscle system physiology variant |
Motor proteins | 0.9535 | INHERITED FROM: neuron physiology variant || ciliated neuron physiology variant || nervous system physiology variant |
Class I aminoacyl-tRNA synthetases (RS), catalytic domain | 1 | INHERITED FROM: receptor mediated endocytosis defective |
SH2 domain | 1 | INHERITED FROM: muscle cell attachment variant || muscle system physiology variant || muscle cell physiology variant |
SCOP term | FDR (all) | Annotation (direct or inherited) |
Ribosomal protein S10 | 0 | Direct |
Transducin (heterotrimeric G protein), gamma chain | 0 | Direct |
RNA-polymerase beta-prime | 0 | Direct |
Ubiquitin carboxyl-terminal hydrolase UCH-L | 0 | Direct |
Sec7 domain | 0 | Direct |
Carbonic anhydrase | 0 | Direct |
XPF/Rad1/Mus81 nuclease | 0 | Direct |
ZZ domain | 0 | Direct |
Serum paraoxonase/arylesterase 1, PON1 | 0 | Direct |
Pepsin-like | 0 | Direct |
L domain | 0 | Direct |
RING finger domain, C3HC4 | 0 | Direct |
Armadillo repeat | 0 | Direct |
Clc chloride channel | 0 | Direct |
Troponin I | 0 | Direct |
Phoshatidylinositol transfer protein, PITP | 0 | Direct |
Phosphoglucomutase, first 3 domains | 0 | Direct |
FabD-like | 0 | Direct |
MutT-like | 0 | Direct |
Matrix metalloproteases, catalytic domain | 0 | Direct |
COMT-like | 0 | Direct |
Roadblock/LC7 domain | 0 | Direct |
Thiolase-related | 0 | Direct |
Type II chitinase | 0 | Direct |
Aminomethyltransferase folate-binding domain | 0 | Direct |
FMN-linked oxidoreductases | 0 | Direct |
Ribonuclease PH domain 1-like | 0 | Direct |
N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
Sir2 family of transcriptional regulators | 0 | Direct |
NADPH-cytochrome p450 reductase-like | 0 | Direct |
FAD/NAD-linked reductases, N-terminal and central domains | 0 | Direct |
CCCH zinc finger | 0 | Direct |
POU-specific domain | 0 | Direct |
Calpain large subunit, middle domain (domain III) | 0 | Direct |
Fibronectin type III | 0 | Direct |
Frizzled cysteine-rich domain | 0 | Direct |
Guanido kinase catalytic domain | 0 | Direct |
alpha-mannosidase | 0 | Direct |
EF-G/eEF-2 domains III and V | 0 | Direct |
YihX-like | 0 | Direct |
Ribonuclease PH domain 2-like | 0 | Direct |
Domain of poly(ADP-ribose) polymerase | 0 | Direct |
Patatin | 0 | Direct |
NTF2-like | 0 | Direct |
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
Protein prenyltransferases | 0 | Direct |
Kix domain of CBP (creb binding protein) | 0 | Direct |
C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
Paired domain | 0 | Direct |
VHS domain | 0 | Direct |
GYF domain | 0 | Direct |
AMPK-beta glycogen binding domain-like | 0 | Direct |
U-box | 0 | Direct |
D-aminoacid oxidase-like | 0 | Direct |
ALDH-like | 0 | Direct |
Proprotein convertase P-domain | 0 | Direct |
C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
H-NOX domain | 0 | Direct |
NagD-like | 0 | Direct |
ValRS/IleRS/LeuRS editing domain | 0 | Direct |
Protein kinase cysteine-rich domain (cys2, phorbol-binding domain) | 0 | Direct |
Hydantoinase (dihydropyrimidinase), catalytic domain | 0 | Direct |
beta-Lactamase/D-ala carboxypeptidase | 0 | Direct |
Elongation factors | 0 | Direct |
Mob1/phocein | 0 | Direct |
Pumilio repeat | 0 | Direct |
Caspase catalytic domain | 0 | Direct |
alpha-catenin/vinculin | 0 | Direct |
Band 7/SPFH domain | 0 | Direct |
Serpins | 0 | Direct |
Hexokinase | 0 | Direct |
Adenylyl and guanylyl cyclase catalytic domain | 0 | Direct |
Oxysterol-binding protein | 0 | Direct |
DPP6 catalytic domain-like | 0 | Direct |
Glutamine synthetase, N-terminal domain | 0 | Direct |
5' to 3' exonuclease catalytic domain | 0 | Direct |
Cofilin-like | 0 | Direct |
Ribonuclease H | 0 | Direct |
Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
Hypothetical protein c14orf129, hspc210 | 0 | Direct |
CO dehydrogenase flavoprotein N-terminal domain-like | 0 | Direct |
Gamma-glutamyltranspeptidase-like | 0 | Direct |
LysM domain | 0 | Direct |
Ypt/Rab-GAP domain of gyp1p | 0 | Direct |
Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain | 0 | Direct |
FYVE, a phosphatidylinositol-3-phosphate binding domain | 0 | Direct |
Mo25 protein | 0 | Direct |
Chitinase insertion domain | 0 | Direct |
Leukotriene A4 hydrolase N-terminal domain | 0 | Direct |
F-box domain | 0 | Direct |
Classic zinc finger, C2H2 | 0 | Direct |
Ran binding protein zinc finger-like | 0 | Direct |
FAD-linked reductases, N-terminal domain | 0 | Direct |
Brix domain | 0 | Direct |
Mitochondrial carrier | 0 | Direct |
NHL repeat | 0 | Direct |
Laminin-type module | 0 | Direct |
Proteasome subunits | 0 | Direct |
Group II chaperonin (CCT, TRIC), ATPase domain | 0 | Direct |
Group II chaperonin (CCT, TRIC), apical domain | 0 | Direct |
WW domain | 0 | Direct |
E2F dimerization segment | 0 | Direct |
Transcriptional factor domain | 0 | Direct |
Inositol monophosphatase/fructose-1,6-bisphosphatase-like | 0 | Direct |
Ribosomal protein L18 and S11 | 0 | Direct |
Dual specificity phosphatase-like | 0 | Direct |
SAM (sterile alpha motif) domain | 0 | Direct |
Histone lysine methyltransferases | 0 | Direct |
Tetramerization domain of potassium channels | 0 | Direct |
Bromodomain | 0 | Direct |
Catalytic, N-terminal domain of histone methyltransferase Dot1l | 0 | Direct |
Thyroglobulin type-1 domain | 0 | Direct |
HSP40/DnaJ peptide-binding domain | 0 | Direct |
Ricin B-like | 0 | Direct |
Ribokinase-like | 0 | Direct |
Cysteine-rich DNA binding domain, (DM domain) | 0 | Direct |
Poly(ADP-ribose) polymerase, C-terminal domain | 0 | Direct |
Actin/HSP70 | 0 | Direct |
CBS-domain pair | 0 | Direct |
Integrin A (or I) domain | 0 | Direct |
Amidase signature (AS) enzymes | 0 | Direct |
Fungal lipases | 0 | Direct |
HSP90 C-terminal domain | 0 | Direct |
Intermediate filament protein, coiled coil region | 0 | Direct |
Clathrin coat assembly domain | 0 | Direct |
Cytochrome b5 | 0 | Direct |
SMAD MH1 domain | 0 | Direct |
CalX-beta domain | 0 | Direct |
Plexin repeat | 0 | Direct |
MIF-related | 0 | Direct |
Transcription factor IIA (TFIIA), alpha-helical domain | 0 | Direct |
BTB/POZ domain | 0 | Direct |
Globins | 0 | Direct |
Cdc48 N-terminal domain-like | 0 | Direct |
Hsp90 middle domain | 0 | Direct |
Class I alpha-1;2-mannosidase, catalytic domain | 0 | Direct |
UBX domain | 0 | Direct |
GAS2 domain | 0 | Direct |
Lactate & malate dehydrogenases, C-terminal domain | 0 | Direct |
Gastric lipase | 0 | Direct |
Bacterial dinuclear zinc exopeptidases | 0 | Direct |
Aldo-keto reductases (NADP) | 0 | Direct |
CRAL/TRIO domain | 0 | Direct |
Ganglioside M2 (gm2) activator | 0 | Direct |
UBC-related | 0 | Direct |
Calcium ATPase, transduction domain A | 0 | Direct |
Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | Direct |
Spectrin repeat | 0 | Direct |
PurM C-terminal domain-like | 0 | Direct |
Cytidylyltransferase | 0 | Direct |
RecA protein-like (ATPase-domain) | 0 | Direct |
Second domain of FERM | 0 | Direct |
CoA-binding domain | 0 | Direct |
Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta | 0 | Direct |
NOL1/NOP2/sun | 0 | Direct |
PEP carboxykinase N-terminal domain | 0 | Direct |
6-phosphogluconate dehydrogenase-like, N-terminal domain | 0 | Direct |
Transforming growth factor (TGF)-beta | 0 | Direct |
IF2B-like | 0 | Direct |
Cytoplasmic domain of inward rectifier potassium channel | 0 | Direct |
Spermadhesin, CUB domain | 0 | Direct |
Profilin (actin-binding protein) | 0 | Direct |
LEM domain | 0 | Direct |
Choline kinase | 0 | Direct |
ATI-like | 0 | Direct |
DEP domain | 0 | Direct |
Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain | 0 | Direct |
Multidomain sulfurtransferase (rhodanese) | 0 | Direct |
Citrate synthase | 0 | Direct |
Pancreatic carboxypeptidases | 0 | Direct |
Phosphatidylethanolamine binding protein | 0 | Direct |
DBL homology domain (DH-domain) | 0 | Direct |
Meta-cation ATPase, catalytic domain P | 0 | Direct |
BAR domain | 0 | Direct |
Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
Histone deacetylase, HDAC | 0 | Direct |
Deoxycytidylate deaminase-like | 0 | Direct |
RhoGDI-like | 0 | Direct |
Cap-Gly domain | 0 | Direct |
CoA transferase alpha subunit-like | 0 | Direct |
Phosphoribosyltransferases (PRTases) | 0 | Direct |
Reductases | 0 | Direct |
Retrovirus zinc finger-like domains | 0 | Direct |
beta 1,4 galactosyltransferase (b4GalT1) | 0 | Direct |
Cystathionine synthase-like | 0 | Direct |
Small Kunitz-type inhibitors & BPTI-like toxins | 0 | Direct |
Hemocyanin middle domain | 0 | Direct |
I set domains | 0 | Direct |
Hedgehog C-terminal (Hog) autoprocessing domain | 0 | Direct |
beta-sandwich domain of Sec23/24 | 0 | Direct |
Clathrin adaptor core protein | 0 | Direct |
Vertebrate phospholipase A2 | 0 | Direct |
TBP-associated factors, TAFs | 0 | Direct |
Alcohol dehydrogenase-like, N-terminal domain | 0 | Direct |
CUT domain | 0 | Direct |
Ferredoxin domains from multidomain proteins | 0 | Direct |
Papain-like | 0 | Direct |
Sec63 N-terminal domain | 0 | Direct |
DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
NLI interacting factor-like phosphatase | 0 | Direct |
Ferredoxin reductase FAD-binding domain-like | 0 | Direct |
SH3-domain | 0 | Direct |
Nitrogenase iron protein-like | 0 | Direct |
SWIRM domain | 0 | Direct |
Sema domain | 0 | Direct |
Translation initiation factor eIF4e | 0 | Direct |
Tetraspanin | 0 | Direct |
Calpain large subunit, catalytic domain (domain II) | 0 | Direct |
PUA domain | 0 | Direct |
YicI catalytic domain-like | 0 | Direct |
Nucleotide and nucleoside kinases | 0 | Direct |
alpha-Amylases, C-terminal beta-sheet domain | 0 | Direct |
TatD Mg-dependent DNase-like | 0 | Direct |
DNA replication initiator (cdc21/cdc54) N-terminal domain | 0 | Direct |
Doublecortin (DC) | 0 | Direct |
Cell cycle transcription factor e2f-dp | 0 | Direct |
DNA repair protein MutS, domain III | 0 | Direct |
UBA domain | 0 | Direct |
Trehalase-like | 0 | Direct |
Aquaporin-like | 0 | Direct |
RUN domain | 0 | Direct |
Pseudouridine synthase I TruA | 0 | Direct |
RNA methyltransferase FtsJ | 0 | Direct |
Quinoprotein alcohol dehydrogenase-like | 0 | Direct |
N-acetylglucosaminyltransferase I | 0 | Direct |
PLC-like (P variant) | 0 | Direct |
Carboxypeptidase regulatory domain | 0 | Direct |
Myotubularin-like phosphatases | 0 | Direct |
acyl-CoA oxidase C-terminal domains | 0 | Direct |
CRAL/TRIO N-terminal domain | 0 | Direct |
4HBT-like | 0 | Direct |
Rap/Ran-GAP | 0 | Direct |
Polo-box duplicated region | 0 | Direct |
Integrin domains | 0 | Direct |
PDI-like | 0 | Direct |
RNA editing terminal uridyl transferase 2, RET2, domain 2 | 0 | Direct |
Cation efflux protein transmembrane domain-like | 0 | Direct |
HAT/Suf repeat | 0 | Direct |
B-box zinc-binding domain | 0 | Direct |
Regulator of chromosome condensation RCC1 | 0 | Direct |
Surp module (SWAP domain) | 0 | Direct |
GABA-aminotransferase-like | 0 | Direct |
Ribosomal protein S18 | 0 | Direct |
Phosphate binding protein-like | 0 | Direct |
Serine carboxypeptidase-like | 0 | Direct |
Tudor domain | 0 | Direct |
Linker histone H1/H5 | 0 | Direct |
PhzC/PhzF-like | 0 | Direct |
Smc hinge domain | 0 | Direct |
TAZ domain | 0 | Direct |
SAP domain | 0 | Direct |
Fibrinogen C-terminal domain-like | 0 | Direct |
Arylsulfatase | 0 | Direct |
SAND domain | 0 | Direct |
p120GAP domain-like | 0 | Direct |
Nucleoside diphosphate kinase, NDK | 0 | Direct |
HD domain | 0 | Direct |
Reprolysin-like | 0 | Direct |
SNARE fusion complex | 0 | Direct |
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
L-arabinose binding protein-like | 0 | Direct |
Phosphotyrosine-binding domain (PTB) | 0 | Direct |
WGR domain | 0 | Direct |
Pyk2-associated protein beta ARF-GAP domain | 0 | Direct |
Calcium ATPase, transmembrane domain M | 0 | Direct |
MIF4G domain-like | 0 | Direct |
Glycogenin | 0 | Direct |
AraD-like aldolase/epimerase | 0 | Direct |
Glycolipid transfer protein, GLTP | 0 | Direct |
Guanido kinase N-terminal domain | 0 | Direct |
SPRY domain | 0 | Direct |
Pepsin inhibitor-3 | 0 | Direct |
L30e/L7ae ribosomal proteins | 0 | Direct |
Eps15 homology domain (EH domain) | 0 | Direct |
Osmotin, thaumatin-like protein | 0 | Direct |
Cdc48 domain 2-like | 0 | Direct |
Heat shock protein 90, HSP90, N-terminal domain | 0 | Direct |
Histidine acid phosphatase | 0 | Direct |
CAT-like | 0 | Direct |
Tubulin, GTPase domain | 0 | Direct |
Hydantoinase (dihydropyrimidinase) | 0 | Direct |
Eukaryotic type KH-domain (KH-domain type I) | 0 | Direct |
EF-hand modules in multidomain proteins | 0 | Direct |
Bacterial lipase | 0 | Direct |
Transcription factor IIA (TFIIA), beta-barrel domain | 0 | Direct |
Ras GEF | 0 | Direct |
Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains | 0 | Direct |
Fatty acid binding protein-like | 0 | Direct |
Growth factor receptor domain | 0 | Direct |
Astacin | 0 | Direct |
Neurotransmitter-gated ion-channel transmembrane pore | 0 | Direct |
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | Direct |
Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain | 0 | Direct |
FAD-dependent thiol oxidase | 0 | Direct |
DEATH domain, DD | 0 | Direct |
Annexin | 0 | Direct |
Class I aldolase | 0 | Direct |
Erythroid transcription factor GATA-1 | 0 | Direct |
Polypeptide N-acetylgalactosaminyltransferase 1, N-terminal domain | 0 | Direct |
Ankyrin repeat | 0 | Direct |
EGF-type module | 0 | Direct |
Cadherin | 0 | Direct |
Ephrin ectodomain | 0 | Direct |
N-type ATP pyrophosphatases | 0 | Direct |
Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | Direct |
Zn-finger domain of Sec23/24 | 0 | Direct |
Sec63 C-terminal domain-like | 0 | Direct |
Filamin repeat (rod domain) | 0 | Direct |
Ribosomal protein L1 | 0 | Direct |
D-aminoacid oxidase, N-terminal domain | 0 | Direct |
Peptidylglycine alpha-hydroxylating monooxygenase, PHM | 0 | Direct |
Prefoldin | 0 | Direct |
F1F0 ATP synthase subunit C | 0 | Direct |
MOSC N-terminal domain-like | 0 | Direct |
beta-glycanases | 0 | Direct |
Kelch motif | 0 | Direct |
Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
Class II glutamine amidotransferases | 0 | Direct |
Family 19 glycosidase | 0 | Direct |
Rhomboid-like | 0 | Direct |
HEAT repeat | 0 | Direct |
PP2C-like | 0 | Direct |
UDPGT-like | 0 | Direct |
Metal cation-transporting ATPase, ATP-binding domain N | 0 | Direct |
PhyH-like | 0 | Direct |
Formin homology 2 domain (FH2 domain) | 0 | Direct |
Neurolysin-like | 0 | Direct |
Ubiquitin-related | 0 | Direct |
NADPH-cytochrome p450 reductase FAD-binding domain-like | 0 | Direct |
Nop domain | 0 | Direct |
Pyridoxal-dependent decarboxylase | 0 | Direct |
Sec1/munc18-like (SM) proteins | 0 | Direct |
PaaI/YdiI-like | 0 | Direct |
5' to 3' exonuclease, C-terminal subdomain | 0 | Direct |
Hect, E3 ligase catalytic domain | 0 | Direct |
Tubulin, C-terminal domain | 0 | Direct |
Choline/Carnitine O-acyltransferase | 0 | Direct |
PABC (PABP) domain | 0 | Direct |
Inositol polyphosphate 5-phosphatase (IPP5) | 0 | Direct |
FCH domain | 0 | Direct |
Bactericidal permeability-increasing protein, BPI | 0 | Direct |
RIO1-like kinases | 0 | Direct |
PDZ domain | 0 | Direct |
alpha-mannosidase, domain 2 | 0 | Direct |
Sterol carrier protein, SCP | 0 | Direct |
Branched-chain alpha-keto acid dehydrogenase Pyr module | 0 | Direct |
Ammonium transporter | 0 | Direct |
Elafin-like | 0 | Direct |
Biotinyl/lipoyl-carrier proteins and domains | 0 | Direct |
14-3-3 protein | 0 | Direct |
AN1-like Zinc finger | 0 | Direct |
Ngr ectodomain-like | 0 | Direct |
Helical domain of Sec23/24 | 0 | Direct |
Cold shock DNA-binding domain-like | 0 | Direct |
N-acetyl transferase, NAT | 0 | Direct |
Aminoacid dehydrogenase-like, C-terminal domain | 0 | Direct |
Medium chain acyl-CoA dehydrogenase-like, C-terminal domain | 0 | Direct |
Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | Direct |
Succinyl-CoA synthetase domains | 0 | Direct |
Internalin LRR domain | 0 | Direct |
Ubiquitin activating enzymes (UBA) | 0 | Direct |
Synaptotagmin-like (S variant) | 0 | Direct |
Multidrug efflux transporter AcrB transmembrane domain | 0 | Direct |
MIT domain | 0 | Direct |
Formate/glycerate dehydrogenases, NAD-domain | 0 | Direct |
EB1 dimerisation domain-like | 0 | Direct |
GAPDH-like | 0 | Direct |
Acyl-CoA binding protein | 0 | Direct |
1,3-glucuronyltransferase | 0 | Direct |
Chaperone J-domain | 0 | Direct |
Diap1 N-terninal region-like | 0 | Direct |
Gelsolin-like | 0 | Direct |
GHMP Kinase, N-terminal domain | 0 | Direct |
Class I glutamine amidotransferases (GAT) | 0 | Direct |
Galectin (animal S-lectin) | 0 | Direct |
HMG-box | 0 | Direct |
Purple acid phosphatase-like | 0 | Direct |
Phoshoinositide 3-kinase (PI3K) helical domain | 0 | Direct |
Molybdenum cofactor-binding domain | 0 | Direct |
AlkB-like | 0 | Direct |
eIF1-like | 0 | Direct |
PX domain | 0 | Direct |
PDEase | 0 | Direct |
ATP-dependent protease Lon (La), catalytic domain | 0 | Direct |
Trunk domain of Sec23/24 | 0 | Direct |
T-box | 0 | Direct |
UDP-glucose pyrophosphorylase | 0 | Direct |
Biotin dependent carboxylase carboxyltransferase domain | 0 | Direct |
Regulator of G-protein signaling, RGS | 0 | Direct |
Ras-binding domain, RBD | 0 | Direct |
Acyl-CoA thioesterase | 0 | Direct |
Myeloperoxidase-like | 0 | Direct |
CO dehydrogenase ISP C-domain like | 0 | Direct |
Acireductone dioxygenase | 0 | Direct |
Alcohol dehydrogenase-like, C-terminal domain | 0 | Direct |
Hermes transposase-like | 0 | Direct |
LacY-like proton/sugar symporter | 0 | Direct |
Lesion bypass DNA polymerase (Y-family), catalytic domain | 0 | Direct |
STAR domain | 0 | Direct |
ABC transporter transmembrane region | 0 | Direct |
Myosin rod fragments | 0 | Direct |
Cyclophilin (peptidylprolyl isomerase) | 0 | Direct |
Pancreatic carboxypeptidase, activation domain | 0 | Direct |
Blood coagulation inhibitor (disintegrin) | 0 | Direct |
Carboxylesterase | 0 | Direct |
HSP20 | 0 | Direct |
alpha-mannosidase, C-terminal domain | 0 | Direct |
RNA-polymerase beta | 0 | Direct |
Creatinase/aminopeptidase | 0 | Direct |
Phoshoinositide 3-kinase (PI3K), catalytic domain | 0 | Direct |
LIM domain | 0 | Direct |
Tropomyosin | 0 | Direct |
Arylamine N-methyltransferase | 0 | Direct |
Skp1 dimerisation domain-like | 0 | Direct |
PR-1-like | 0 | Direct |
Zf-UBP | 0 | Direct |
Pleckstrin-homology domain (PH domain) | 0 | Direct |
FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | Direct |
Purple acid phosphatase, N-terminal domain | 0 | Direct |
Sm motif of small nuclear ribonucleoproteins, SNRNP | 0 | Direct |
S-adenosylmethionine synthetase | 0 | Direct |
Hemopexin-like domain | 0 | Direct |
Branched-chain alpha-keto acid dehydrogenase PP module | 0 | Direct |
LDL receptor-like module | 0 | Direct |
Inhibitor of apoptosis (IAP) repeat | 0 | Direct |
Transducin (alpha subunit), insertion domain | 0 | Direct |
Aminomethyltransferase beta-barrel domain | 0 | Direct |
HCDH C-domain-like | 0 | Direct |
28-residue LRR | 0 | Direct |
FtsH protease domain-like | 0 | Direct |
beta-CASP RNA-metabolising hydrolases | 0 | Direct |
SWIB/MDM2 domain | 0 | Direct |
MFPT repeat | 0 | Direct |
Subtilases | 0 | Direct |
BC N-terminal domain-like | 0 | Direct |
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
Glycerol-3-phosphate transporter | 0 | Direct |
MIR domain | 0 | Direct |
Small-conductance potassium channel | 0 | Direct |
Cation efflux protein cytoplasmic domain-like | 0 | Direct |
Arfaptin, Rac-binding fragment | 0 | Direct |
Lipovitellin-phosvitin complex, superhelical domain | 0 | Direct |
Myb/SANT domain | 0 | Direct |
Third domain of FERM | 0 | Direct |
BC C-terminal domain-like | 0 | Direct |
Smr domain | 0 | Direct |
Supernatant protein factor (SPF), C-terminal domain | 0 | Direct |
YbiA-like | 0 | Direct |
Glycerol kinase | 0 | Direct |
PurM N-terminal domain-like | 0 | Direct |
L-aminoacid/polyamine oxidase | 0 | Direct |
HLH, helix-loop-helix DNA-binding domain | 0 | Direct |
Rv2717c-like | 0 | Direct |
BEACH domain | 0 | Direct |
BC ATP-binding domain-like | 0 | Direct |
DPP6 N-terminal domain-like | 0 | Direct |
SMAD domain | 0 | Direct |
Acylamino-acid-releasing enzyme, C-terminal donain | 0 | Direct |
BolA-like | 0 | Direct |
Glycerophosphoryl diester phosphodiesterase | 0 | Direct |
BSD domain | 0 | Direct |
WWE domain | 0 | Direct |
Dimeric isocitrate & isopropylmalate dehydrogenases | 0 | Direct |
Methionine aminopeptidase, insert domain | 0 | Direct |
Anticodon-binding domain | 0 | Direct |
Tim10/DDP | 0 | Direct |
Chromo domain | 0 | Direct |
FF domain | 0 | Direct |
t-snare proteins | 0 | Direct |
Glutamine synthetase catalytic domain | 0 | Direct |
Anticodon-binding domain of Class II aaRS | 0 | Direct |
FHA domain | 0 | Direct |
Acyl-carrier protein (ACP) | 0 | Direct |
Arginine methyltransferase | 0 | Direct |
Amylase, catalytic domain | 0 | Direct |
PEP carboxykinase C-terminal domain | 0 | Direct |
First domain of FERM | 0 | Direct |
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | Direct |
Hormone receptor domain | 0 | Direct |
ARID domain | 0 | Direct |
CO dehydrogenase molybdoprotein N-domain-like | 0 | Direct |
La domain | 0 | Direct |
Adenain-like | 0 | Direct |
Heme-dependent catalases | 0 | Direct |
Epoxide hydrolase | 0 | Direct |
Laminin G-like module | 0 | Direct |
Calmodulin-like | 0 | Direct |
2Fe-2S ferredoxin domains from multidomain proteins | 0 | Direct |
LDH N-terminal domain-like | 0 | Direct |
Autophagin-like | 0 | Direct |
Inositol polyphosphate kinase (IPK) | 0 | Direct |
YWTD domain | 0 | Direct |
Leukotriene A4 hydrolase catalytic domain | 0 | Direct |
cAMP-binding domain | 0 | Direct |
Cu,Zn superoxide dismutase-like | 0 | Direct |
Complement control module/SCR domain | 0 | Direct |
Cell cycle control phosphatase, catalytic domain | 0 | Direct |
ets domain | 0 | Direct |
Group II chaperonin (CCT, TRIC), intermediate domain | 0 | Direct |
Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
Glutaminase | 0 | Direct |
Proton glutamate symport protein | 0 | Direct |
Mammalian PLC | 0 | Direct |
Kinase associated domain 1, KA1 | 0 | Direct |
Crotonase-like | 0 | Direct |
Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain | 0 | Direct |
Translational machinery components | 0 | Direct |
Bacterial exopeptidase dimerisation domain | 0 | Direct |
acyl-CoA oxidase N-terminal domains | 0 | Direct |
Calponin-homology domain, CH-domain | 0 | Direct |
Single strand DNA-binding domain, SSB | 0 | Direct |
Canonical RBD | 0.2513 | Inherited |
MSP-like | 0.2803 | Inherited |
Nicotinic receptor ligand binding domain-like | 0.2803 | Inherited |
Voltage-gated potassium channels | 0.3239 | Inherited |
Tandem AAA-ATPase domain | 0.3341 | Inherited |
G proteins | 0.4101 | Inherited |
Homeodomain | 0.6761 | Inherited |
BCR-homology GTPase activation domain (BH-domain) | 0.7908 | Inherited |
WD40-repeat | 0.8104 | Inherited |
Cyclin | 0.8382 | Inherited |
Protein kinases, catalytic subunit | 0.9024 | Inherited |
Lamin A/C globular tail domain | 0.9522 | Inherited |
Motor proteins | 0.9535 | Inherited |
Class I aminoacyl-tRNA synthetases (RS), catalytic domain | 1 | Inherited |
SH2 domain | 1 | Inherited |
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A presence/absence matrix is generated using protein domain
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Supra-domain (including individual superfamily)
(show details)
Supra-domains annotated to this WP term (Not in SPWP)
Highlighted in gray are those with FDR>0.001
Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
Radical SAM enzymes | 0 | DIRECT |
Nop domain | 0 | DIRECT |
Cadherin-like | 0 | DIRECT |
5' to 3' exonuclease, C-terminal subdomain | 0 | DIRECT |
FAD/NAD(P)-binding domain | 0 | DIRECT |
Acyl-CoA dehydrogenase NM domain-like | 0 | DIRECT |
SMAD MH1 domain | 0 | DIRECT |
Bromodomain | 0 | DIRECT |
AN1-like Zinc finger | 0 | DIRECT |
Spectrin repeat | 0 | DIRECT |
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | DIRECT |
DBL homology domain (DH-domain) | 0 | DIRECT |
Hormone receptor domain | 0 | DIRECT |
ACP-like | 0 | DIRECT |
PEP carboxykinase N-terminal domain | 0 | DIRECT |
FF domain | 0 | DIRECT |
HCP-like | 0 | DIRECT |
Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | DIRECT |
EGF/Laminin | 0 | DIRECT |
Ganglioside M2 (gm2) activator | 0 | DIRECT |
C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
WWE domain | 0 | DIRECT |
Transcription factor IIA (TFIIA), beta-barrel domain | 0 | DIRECT |
SET domain | 0 | DIRECT |
Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
Flavoproteins | 0 | DIRECT |
alpha-catenin/vinculin-like | 0 | DIRECT |
NAD kinase/diacylglycerol kinase-like | 0 | DIRECT |
Ricin B-like lectins | 0 | DIRECT |
Nucleoside diphosphate kinase, NDK | 0 | DIRECT |
Helical domain of Sec23/24 | 0 | DIRECT |
Tricorn protease domain 2 | 0 | DIRECT |
DEATH domain | 0 | DIRECT |
Mitochondrial cytochrome c oxidase subunit VIc | 0 | DIRECT |
Subdomain of clathrin and coatomer appendage domain | 0 | DIRECT |
Galactose mutarotase-like | 0 | DIRECT |
Tetraspanin | 0 | DIRECT |
Bet v1-like | 0 | DIRECT |
Quinoprotein alcohol dehydrogenase-like | 0 | DIRECT |
EB1 dimerisation domain-like | 0 | DIRECT |
DHS-like NAD/FAD-binding domain | 0 | DIRECT |
WW domain | 0 | DIRECT |
PUA domain-like | 0 | DIRECT |
Phosphoenolpyruvate/pyruvate domain | 0 | DIRECT |
Ribokinase-like | 0 | DIRECT |
Band 7/SPFH domain | 0 | DIRECT |
Metallo-dependent hydrolases | 0 | DIRECT |
GroEL apical domain-like | 0 | DIRECT |
Surp module (SWAP domain) | 0 | DIRECT |
Cdc48 domain 2-like | 0 | DIRECT |
Ribulose-phoshate binding barrel | 0 | DIRECT |
CoA-dependent acyltransferases | 0 | DIRECT |
ArfGap/RecO-like zinc finger | 0 | DIRECT |
MIR domain | 0 | DIRECT |
Calcium-dependent phosphotriesterase | 0 | DIRECT |
Glutamine synthetase/guanido kinase | 0 | DIRECT |
CAD & PB1 domains | 0 | DIRECT |
Hedgehog/intein (Hint) domain | 0 | DIRECT |
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
RUN domain-like | 0 | DIRECT |
Glutathione synthetase ATP-binding domain-like | 0 | DIRECT |
TK C-terminal domain-like | 0 | DIRECT |
FAD-dependent thiol oxidase | 0 | DIRECT |
Caspase-like | 0 | DIRECT |
Hemopexin-like domain | 0 | DIRECT |
PDZ domain-like | 0 | DIRECT |
NTF2-like | 0 | DIRECT |
ADP-ribosylation | 0 | DIRECT |
LDH C-terminal domain-like | 0 | DIRECT |
LDL receptor-like module | 0 | DIRECT |
Hairpin loop containing domain-like | 0 | DIRECT |
Formin homology 2 domain (FH2 domain) | 0 | DIRECT |
Single hybrid motif | 0 | DIRECT |
Galactose oxidase, central domain | 0 | DIRECT |
Supernatant protein factor (SPF), C-terminal domain | 0 | DIRECT |
Ribosomal protein L1 | 0 | DIRECT |
FAD-linked reductases, C-terminal domain | 0 | DIRECT |
PGBD-like | 0 | DIRECT |
Second domain of FERM | 0 | DIRECT |
MgtE membrane domain-like | 0 | DIRECT |
Tautomerase/MIF | 0 | DIRECT |
Ribosomal protein S10 | 0 | DIRECT |
Phosphoglucomutase, first 3 domains | 0 | DIRECT |
RCC1/BLIP-II | 0 | DIRECT |
Ferritin-like | 0 | DIRECT |
Tubby C-terminal domain-like | 0 | DIRECT |
Restriction endonuclease-like | 0 | DIRECT |
SWIB/MDM2 domain | 0 | DIRECT |
Chromo domain-like | 0 | DIRECT |
Cu,Zn superoxide dismutase-like | 0 | DIRECT |
Chitinase insertion domain | 0 | DIRECT |
Prefoldin | 0 | DIRECT |
Sema domain | 0 | DIRECT |
Zn-finger domain of Sec23/24 | 0 | DIRECT |
Oxysterol-binding protein-like | 0 | DIRECT |
PYP-like sensor domain (PAS domain) | 0 | DIRECT |
Myosin rod fragments | 0 | DIRECT |
t-snare proteins | 0 | DIRECT |
N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
Nudix | 0 | DIRECT |
DNA ligase/mRNA capping enzyme, catalytic domain | 0 | DIRECT |
MOSC N-terminal domain-like | 0 | DIRECT |
Cytidine deaminase-like | 0 | DIRECT |
Bactericidal permeability-increasing protein, BPI | 0 | DIRECT |
ABC transporter transmembrane region | 0 | DIRECT |
BolA-like | 0 | DIRECT |
PHM/PNGase F | 0 | DIRECT |
Cysteine-rich DNA binding domain, (DM domain) | 0 | DIRECT |
PABC (PABP) domain | 0 | DIRECT |
Clc chloride channel | 0 | DIRECT |
Phoshotransferase/anion transport protein | 0 | DIRECT |
FMN-linked oxidoreductases | 0 | DIRECT |
Kelch motif | 0 | DIRECT |
SAND domain-like | 0 | DIRECT |
GroES-like | 0 | DIRECT |
Creatinase/aminopeptidase | 0 | DIRECT |
Families 57/38 glycoside transferase middle domain | 0 | DIRECT |
Periplasmic binding protein-like I | 0 | DIRECT |
Ran binding protein zinc finger-like | 0 | DIRECT |
Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | DIRECT |
Calcium ATPase, transduction domain A | 0 | DIRECT |
Clathrin adaptor appendage domain | 0 | DIRECT |
FabD/lysophospholipase-like | 0 | DIRECT |
PRTase-like | 0 | DIRECT |
ENTH/VHS domain | 0 | DIRECT |
Spermadhesin, CUB domain | 0 | DIRECT |
FtsH protease domain-like | 0 | DIRECT |
SNARE-like | 0 | DIRECT |
ALDH-like | 0 | DIRECT |
B-box zinc-binding domain | 0 | DIRECT |
Phosphoglycerate mutase-like | 0 | DIRECT |
Alpha-L RNA-binding motif | 0 | DIRECT |
PurM N-terminal domain-like | 0 | DIRECT |
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | DIRECT |
Cysteine-rich domain | 0 | DIRECT |
HSP90 C-terminal domain | 0 | DIRECT |
CalX-like | 0 | DIRECT |
Glycoside hydrolase/deacetylase | 0 | DIRECT |
Translation proteins SH3-like domain | 0 | DIRECT |
Mob1/phocein | 0 | DIRECT |
DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
LysM domain | 0 | DIRECT |
Acyl-CoA N-acyltransferases (Nat) | 0 | DIRECT |
PreATP-grasp domain | 0 | DIRECT |
EF-G C-terminal domain-like | 0 | DIRECT |
Class II aaRS and biotin synthetases | 0 | DIRECT |
p53-like transcription factors | 0 | DIRECT |
HSP20-like chaperones | 0 | DIRECT |
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
Seven-hairpin glycosidases | 0 | DIRECT |
Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
Plexin repeat | 0 | DIRECT |
Thyroglobulin type-1 domain | 0 | DIRECT |
Domain of poly(ADP-ribose) polymerase | 0 | DIRECT |
Integrin alpha N-terminal domain | 0 | DIRECT |
Ypt/Rab-GAP domain of gyp1p | 0 | DIRECT |
ThrRS/AlaRS common domain | 0 | DIRECT |
DNA repair protein MutS, domain III | 0 | DIRECT |
SpoIIaa-like | 0 | DIRECT |
Amidase signature (AS) enzymes | 0 | DIRECT |
alpha-helical ferredoxin | 0 | DIRECT |
beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | DIRECT |
Polo-box domain | 0 | DIRECT |
Class I glutamine amidotransferase-like | 0 | DIRECT |
C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
MFPT repeat-like | 0 | DIRECT |
Tubulin C-terminal domain-like | 0 | DIRECT |
Regulator of G-protein signaling, RGS | 0 | DIRECT |
Cupredoxins | 0 | DIRECT |
CRAL/TRIO domain | 0 | DIRECT |
Phospholipase D/nuclease | 0 | DIRECT |
Troponin coil-coiled subunits | 0 | DIRECT |
Sec7 domain | 0 | DIRECT |
Inhibitor of apoptosis (IAP) repeat | 0 | DIRECT |
NagB/RpiA/CoA transferase-like | 0 | DIRECT |
Clavaminate synthase-like | 0 | DIRECT |
Molybdenum cofactor biosynthesis proteins | 0 | DIRECT |
Pepsin inhibitor-3 | 0 | DIRECT |
cAMP-binding domain-like | 0 | DIRECT |
PK beta-barrel domain-like | 0 | DIRECT |
ValRS/IleRS/LeuRS editing domain | 0 | DIRECT |
Cystatin/monellin | 0 | DIRECT |
Glutamine synthetase, N-terminal domain | 0 | DIRECT |
Molybdenum cofactor-binding domain | 0 | DIRECT |
GAT-like domain | 0 | DIRECT |
Multidrug resistance efflux transporter EmrE | 0 | DIRECT |
BSD domain-like | 0 | DIRECT |
SMAD/FHA domain | 0 | DIRECT |
Purple acid phosphatase, N-terminal domain | 0 | DIRECT |
GHMP Kinase, C-terminal domain | 0 | DIRECT |
F1F0 ATP synthase subunit C | 0 | DIRECT |
Concanavalin A-like lectins/glucanases | 0 | DIRECT |
R3H domain | 0 | DIRECT |
eIF4e-like | 0 | DIRECT |
Thiolase-like | 0 | DIRECT |
Ribosomal L27 protein-like | 0 | DIRECT |
Rhodanese/Cell cycle control phosphatase | 0 | DIRECT |
S-adenosylmethionine synthetase | 0 | DIRECT |
TIMP-like | 0 | DIRECT |
Ribosomal protein L10-like | 0 | DIRECT |
C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
Ribosomal proteins S24e, L23 and L15e | 0 | DIRECT |
Hect, E3 ligase catalytic domain | 0 | DIRECT |
Smc hinge domain | 0 | DIRECT |
Kringle-like | 0 | DIRECT |
HMG-box | 0 | DIRECT |
beta-sandwich domain of Sec23/24 | 0 | DIRECT |
Six-hairpin glycosidases | 0 | DIRECT |
CCCH zinc finger | 0 | DIRECT |
Leukotriene A4 hydrolase N-terminal domain | 0 | DIRECT |
L30e-like | 0 | DIRECT |
Adenine nucleotide alpha hydrolases-like | 0 | DIRECT |
Skp1 dimerisation domain-like | 0 | DIRECT |
NHL repeat | 0 | DIRECT |
3-carboxy-cis,cis-mucoante lactonizing enzyme | 0 | DIRECT |
Zinc beta-ribbon | 0 | DIRECT |
SH3-domain | 0 | DIRECT |
Ribosomal protein S18 | 0 | DIRECT |
Doublecortin (DC) | 0 | DIRECT |
Profilin (actin-binding protein) | 0 | DIRECT |
Pectin lyase-like | 0 | DIRECT |
UBA-like | 0 | DIRECT |
Rap/Ran-GAP | 0 | DIRECT |
Osmotin, thaumatin-like protein | 0 | DIRECT |
Heme-dependent peroxidases | 0 | DIRECT |
Serine protease inhibitors | 0 | DIRECT |
Invertebrate chitin-binding proteins | 0 | DIRECT |
Aminomethyltransferase beta-barrel domain | 0 | DIRECT |
Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
CBD9-like | 0 | DIRECT |
GYF domain | 0 | DIRECT |
Calponin-homology domain, CH-domain | 0 | DIRECT |
Actin-like ATPase domain | 0 | DIRECT |
Transducin (heterotrimeric G protein), gamma chain | 0 | DIRECT |
Diaminopimelate epimerase-like | 0 | DIRECT |
Transducin (alpha subunit), insertion domain | 0 | DIRECT |
SAICAR synthase-like | 0 | DIRECT |
Cyclophilin-like | 0 | DIRECT |
Nucleoporin domain | 0 | DIRECT |
Terpenoid cyclases/Protein prenyltransferases | 0 | DIRECT |
PEP carboxykinase-like | 0 | DIRECT |
Metallo-hydrolase/oxidoreductase | 0 | DIRECT |
Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
L domain-like | 0 | DIRECT |
HIT-like | 0 | DIRECT |
Alkaline phosphatase-like | 0 | DIRECT |
E2F-DP heterodimerization region | 0 | DIRECT |
Pseudouridine synthase | 0 | DIRECT |
Hypothetical protein c14orf129, hspc210 | 0 | DIRECT |
Multidrug efflux transporter AcrB transmembrane domain | 0 | DIRECT |
Nucleic acid-binding proteins | 0 | DIRECT |
N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0 | DIRECT |
Aldolase | 0 | DIRECT |
Immunoglobulin | 0 | DIRECT |
Isocitrate/Isopropylmalate dehydrogenase-like | 0 | DIRECT |
Mitochondrial carrier | 0 | DIRECT |
Cytochrome b5-like heme/steroid binding domain | 0 | DIRECT |
Cap-Gly domain | 0 | DIRECT |
Rudiment single hybrid motif | 0 | DIRECT |
Frizzled cysteine-rich domain | 0 | DIRECT |
YWTD domain | 0 | DIRECT |
RBP11-like subunits of RNA polymerase | 0 | DIRECT |
Protease propeptides/inhibitors | 0 | DIRECT |
SCP-like | 0 | DIRECT |
Ammonium transporter | 0 | DIRECT |
YbiA-like | 0 | DIRECT |
Citrate synthase | 0 | DIRECT |
GroEL equatorial domain-like | 0 | DIRECT |
DNase I-like | 0 | DIRECT |
eIF1-like | 0 | DIRECT |
KA1-like | 0 | DIRECT |
HD-domain/PDEase-like | 0 | DIRECT |
Actin depolymerizing proteins | 0 | DIRECT |
UBC-like | 0 | DIRECT |
CO dehydrogenase molybdoprotein N-domain-like | 0 | DIRECT |
Intermediate filament protein, coiled coil region | 0 | DIRECT |
Thioesterase/thiol ester dehydrase-isomerase | 0 | DIRECT |
Nucleotide-binding domain | 0 | DIRECT |
ADC-like | 0 | DIRECT |
PIN domain-like | 0 | DIRECT |
PurM C-terminal domain-like | 0 | DIRECT |
Lipocalins | 0 | DIRECT |
Glycerol-3-phosphate (1)-acyltransferase | 0 | DIRECT |
AraD/HMP-PK domain-like | 0 | DIRECT |
SPOC domain-like | 0 | DIRECT |
HLH, helix-loop-helix DNA-binding domain | 0 | DIRECT |
The spindle assembly checkpoint protein mad2 | 0 | DIRECT |
Activating enzymes of the ubiquitin-like proteins | 0 | DIRECT |
Blood coagulation inhibitor (disintegrin) | 0 | DIRECT |
Tropomyosin | 0 | DIRECT |
CRAL/TRIO N-terminal domain | 0 | DIRECT |
L-aspartase-like | 0 | DIRECT |
ARID-like | 0 | DIRECT |
HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
Kix domain of CBP (creb binding protein) | 0 | DIRECT |
Glycosyl hydrolase domain | 0 | DIRECT |
Aquaporin-like | 0 | DIRECT |
Calpain large subunit, middle domain (domain III) | 0 | DIRECT |
Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
Sm-like ribonucleoproteins | 0 | DIRECT |
VPS9 domain | 0 | DIRECT |
Periplasmic binding protein-like II | 0 | DIRECT |
LEM domain | 0 | DIRECT |
Proton glutamate symport protein | 0 | DIRECT |
Class II aaRS ABD-related | 0 | DIRECT |
Complement control module/SCR domain | 0 | DIRECT |
Fibronectin type III | 0 | DIRECT |
Fibrinogen C-terminal domain-like | 0 | DIRECT |
Cation efflux protein cytoplasmic domain-like | 0 | DIRECT |
Carbon-nitrogen hydrolase | 0 | DIRECT |
TAZ domain | 0 | DIRECT |
FAD-binding/transporter-associated domain-like | 0 | DIRECT |
lambda repressor-like DNA-binding domains | 0 | DIRECT |
Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
Growth factor receptor domain | 0 | DIRECT |
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0 | DIRECT |
Thiamin diphosphate-binding fold (THDP-binding) | 0 | DIRECT |
Small-conductance potassium channel | 0 | DIRECT |
Guanido kinase N-terminal domain | 0 | DIRECT |
HIT/MYND zinc finger-like | 0 | DIRECT |
Creatinase/prolidase N-terminal domain | 0 | DIRECT |
GroEL-intermediate domain like | 0 | DIRECT |
PH domain-like | 0 | DIRECT |
Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | DIRECT |
SAP domain | 0 | DIRECT |
Folate-binding domain | 0 | DIRECT |
HRDC-like | 0 | DIRECT |
GAS2 domain-like | 0 | DIRECT |
Acid phosphatase/Vanadium-dependent haloperoxidase | 0 | DIRECT |
BEACH domain | 0 | DIRECT |
Ribonuclease PH domain 2-like | 0 | DIRECT |
Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | DIRECT |
PEBP-like | 0 | DIRECT |
6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | DIRECT |
PAP/OAS1 substrate-binding domain | 0 | DIRECT |
Outer arm dynein light chain 1 | 0 | DIRECT |
2Fe-2S ferredoxin-like | 0 | DIRECT |
ISP domain | 0 | DIRECT |
Bacterial exopeptidase dimerisation domain | 0 | DIRECT |
PLC-like phosphodiesterases | 0 | DIRECT |
Rhomboid-like | 0 | DIRECT |
Cation efflux protein transmembrane domain-like | 0 | DIRECT |
SNARE fusion complex | 0 | DIRECT |
RmlC-like cupins | 0 | DIRECT |
beta-lactamase/transpeptidase-like | 0 | DIRECT |
Aminoacid dehydrogenase-like, N-terminal domain | 0 | DIRECT |
ClpP/crotonase | 0 | DIRECT |
Ankyrin repeat | 0 | DIRECT |
Elafin-like | 0 | DIRECT |
Chaperone J-domain | 0 | DIRECT |
Putative DNA-binding domain | 0 | DIRECT |
SAM/Pointed domain | 0 | DIRECT |
Formate/glycerate dehydrogenase catalytic domain-like | 0 | DIRECT |
BPTI-like | 0 | DIRECT |
WGR domain-like | 0 | DIRECT |
Translation proteins | 0 | DIRECT |
Lysozyme-like | 0 | DIRECT |
NAD(P)-linked oxidoreductase | 0 | DIRECT |
Acid proteases | 0 | DIRECT |
Di-copper centre-containing domain | 0 | DIRECT |
alpha/beta knot | 0 | DIRECT |
vWA-like | 0 | DIRECT |
Transcription factor IIA (TFIIA), alpha-helical domain | 0 | DIRECT |
4Fe-4S ferredoxins | 0 | DIRECT |
Tubulin nucleotide-binding domain-like | 0 | DIRECT |
BAR/IMD domain-like | 0 | DIRECT |
Roadblock/LC7 domain | 0 | DIRECT |
Arginase/deacetylase | 0 | DIRECT |
Pentein | 0 | DIRECT |
Mss4-like | 0 | DIRECT |
Eukaryotic type KH-domain (KH-domain type I) | 0 | DIRECT |
PP2C-like | 0 | DIRECT |
Riboflavin synthase domain-like | 0 | DIRECT |
Nucleotidyltransferase | 0 | DIRECT |
Retrovirus zinc finger-like domains | 0 | DIRECT |
Integrin domains | 0 | DIRECT |
SGNH hydrolase | 0 | DIRECT |
Tudor/PWWP/MBT | 0 | DIRECT |
Ras GEF | 0 | DIRECT |
BRCT domain | 0 | DIRECT |
FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | DIRECT |
SIS domain | 0 | DIRECT |
MIT domain | 0 | DIRECT |
RuvA domain 2-like | 0 | DIRECT |
CO dehydrogenase ISP C-domain like | 0 | DIRECT |
Metal cation-transporting ATPase, ATP-binding domain N | 0 | DIRECT |
Carbonic anhydrase | 0 | DIRECT |
Cystine-knot cytokines | 0 | DIRECT |
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | DIRECT |
Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
TGS-like | 0 | DIRECT |
Sec1/munc18-like (SM) proteins | 0 | DIRECT |
Annexin | 0 | DIRECT |
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
Terpenoid synthases | 0 | DIRECT |
14-3-3 protein | 0 | DIRECT |
Carbohydrate phosphatase | 0 | DIRECT |
S-adenosyl-L-methionine-dependent methyltransferases | 0 | DIRECT |
Lipovitellin-phosvitin complex, superhelical domain | 0 | DIRECT |
Tim10-like | 0 | DIRECT |
DNA clamp | 0 | DIRECT |
HAD-like | 0 | DIRECT |
DPP6 N-terminal domain-like | 0 | DIRECT |
PLP-binding barrel | 0 | DIRECT |
PX domain | 0 | DIRECT |
Acyl-CoA binding protein | 0 | DIRECT |
Carboxypeptidase regulatory domain-like | 0 | DIRECT |
Actin-crosslinking proteins | 0 | DIRECT |
Phospholipase A2, PLA2 | 0 | DIRECT |
CBS-domain pair | 0 | DIRECT |
Nucleotide-diphospho-sugar transferases | 0 | DIRECT |
Translational machinery components | 0 | DIRECT |
Nucleotide cyclase | 0 | DIRECT |
Sec63 N-terminal domain-like | 0 | DIRECT |
Calcium ATPase, transmembrane domain M | 0 | DIRECT |
Subtilisin-like | 0 | DIRECT |
Glycolipid transfer protein, GLTP | 0 | DIRECT |
PR-1-like | 0 | DIRECT |
Succinyl-CoA synthetase domains | 0 | DIRECT |
Cytochrome c | 0 | DIRECT |
Heme-dependent catalase-like | 0 | DIRECT |
SMR domain-like | 0 | DIRECT |
FAD-linked oxidases, C-terminal domain | 0 | DIRECT |
ARM repeat | 0.0719 | INHERITED FROM: brood size variant || germ cell physiology variant || epithelial system physiology variant |
RNA-binding domain, RBD | 0.195 | INHERITED FROM: sterile F1 || brood size variant |
PapD-like | 0.231 | INHERITED FROM: sterile progeny |
Nicotinic receptor ligand binding domain-like | 0.2577 | INHERITED FROM: coelomic system physiology variant || coelomocyte uptake defective || coelomocyte physiology variant || transmission of nerve impulse variant || nervous system physiology variant || synaptic transmission variant |
Voltage-gated potassium channels | 0.3048 | INHERITED FROM: muscle cell activity variant |
Neurotransmitter-gated ion-channel transmembrane pore | 0.3094 | INHERITED FROM: coelomic system physiology variant || coelomocyte uptake defective || coelomocyte physiology variant || transmission of nerve impulse variant || nervous system physiology variant || synaptic transmission variant |
Ubiquitin-like | 0.3495 | INHERITED FROM: muscle cell physiology variant || muscle system physiology variant || body muscle dystrophy |
Metallo-dependent phosphatases | 0.4155 | INHERITED FROM: germ cell resistant ionizing radiation || radiation induced germ cell apoptosis resistant |
FYVE/PHD zinc finger | 0.5098 | INHERITED FROM: coelomic system physiology variant || coelomocyte uptake defective || coelomocyte physiology variant || transgenerational loss of fertility |
EF-hand | 0.6033 | INHERITED FROM: muscle cell physiology variant || gonad sheath contractions variant || muscle system physiology variant || somatic gonad physiology variant || somatic sheath physiology variant |
WD40 repeat-like | 0.6454 | INHERITED FROM: brood size variant || germ cell physiology variant || reduced brood size |
TPR-like | 0.6671 | INHERITED FROM: male gonad development variant |
GTPase activation domain, GAP | 0.7197 | INHERITED FROM: muscle cell attachment variant || muscle cell physiology variant || muscle system physiology variant |
P-loop containing nucleoside triphosphate hydrolases | 0.7215 | INHERITED FROM: postsynaptic region physiology variant || brood size variant || germ cell physiology variant || nervous system physiology variant || male gonad development variant |
Saposin | 0.7714 | INHERITED FROM: germ cell resistant ionizing radiation || germ cell ionizing radiation response variant || radiation induced germ cell apoptosis resistant |
(Phosphotyrosine protein) phosphatases II | 0.8038 | INHERITED FROM: muscle cell attachment variant |
"Winged helix" DNA-binding domain | 0.8739 | INHERITED FROM: germline mortal || brood size variant || muscle dystrophy || male gonad development variant || body muscle dystrophy |
RING/U-box | 0.895 | INHERITED FROM: germ cell ionizing radiation response variant || germ cell hypersensitive ionizing radiation |
Lamin A/C globular tail domain | 0.9336 | INHERITED FROM: muscle system physiology variant |
PLP-dependent transferases | 0.9409 | INHERITED FROM: germ cell resistant ionizing radiation || radiation induced germ cell apoptosis resistant |
SH2 domain | 1 | INHERITED FROM: muscle cell attachment variant || muscle cell physiology variant || muscle system physiology variant |
Protein kinase-like (PK-like) | 1 | INHERITED FROM: muscle cell physiology variant || muscle system physiology variant || body muscle dystrophy |
Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
Radical SAM enzymes | 0 | Direct |
Nop domain | 0 | Direct |
Cadherin-like | 0 | Direct |
5' to 3' exonuclease, C-terminal subdomain | 0 | Direct |
FAD/NAD(P)-binding domain | 0 | Direct |
Acyl-CoA dehydrogenase NM domain-like | 0 | Direct |
SMAD MH1 domain | 0 | Direct |
Bromodomain | 0 | Direct |
AN1-like Zinc finger | 0 | Direct |
Spectrin repeat | 0 | Direct |
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | Direct |
DBL homology domain (DH-domain) | 0 | Direct |
Hormone receptor domain | 0 | Direct |
ACP-like | 0 | Direct |
PEP carboxykinase N-terminal domain | 0 | Direct |
FF domain | 0 | Direct |
HCP-like | 0 | Direct |
Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | Direct |
EGF/Laminin | 0 | Direct |
Ganglioside M2 (gm2) activator | 0 | Direct |
C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
WWE domain | 0 | Direct |
Transcription factor IIA (TFIIA), beta-barrel domain | 0 | Direct |
SET domain | 0 | Direct |
Phosphoglucomutase, C-terminal domain | 0 | Direct |
Flavoproteins | 0 | Direct |
alpha-catenin/vinculin-like | 0 | Direct |
NAD kinase/diacylglycerol kinase-like | 0 | Direct |
Ricin B-like lectins | 0 | Direct |
Nucleoside diphosphate kinase, NDK | 0 | Direct |
Helical domain of Sec23/24 | 0 | Direct |
Tricorn protease domain 2 | 0 | Direct |
DEATH domain | 0 | Direct |
Mitochondrial cytochrome c oxidase subunit VIc | 0 | Direct |
Subdomain of clathrin and coatomer appendage domain | 0 | Direct |
Galactose mutarotase-like | 0 | Direct |
Tetraspanin | 0 | Direct |
Bet v1-like | 0 | Direct |
Quinoprotein alcohol dehydrogenase-like | 0 | Direct |
EB1 dimerisation domain-like | 0 | Direct |
DHS-like NAD/FAD-binding domain | 0 | Direct |
WW domain | 0 | Direct |
PUA domain-like | 0 | Direct |
Phosphoenolpyruvate/pyruvate domain | 0 | Direct |
Ribokinase-like | 0 | Direct |
Band 7/SPFH domain | 0 | Direct |
Metallo-dependent hydrolases | 0 | Direct |
GroEL apical domain-like | 0 | Direct |
Surp module (SWAP domain) | 0 | Direct |
Cdc48 domain 2-like | 0 | Direct |
Ribulose-phoshate binding barrel | 0 | Direct |
CoA-dependent acyltransferases | 0 | Direct |
ArfGap/RecO-like zinc finger | 0 | Direct |
MIR domain | 0 | Direct |
Calcium-dependent phosphotriesterase | 0 | Direct |
Glutamine synthetase/guanido kinase | 0 | Direct |
CAD & PB1 domains | 0 | Direct |
Hedgehog/intein (Hint) domain | 0 | Direct |
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
RUN domain-like | 0 | Direct |
Glutathione synthetase ATP-binding domain-like | 0 | Direct |
TK C-terminal domain-like | 0 | Direct |
FAD-dependent thiol oxidase | 0 | Direct |
Caspase-like | 0 | Direct |
Hemopexin-like domain | 0 | Direct |
PDZ domain-like | 0 | Direct |
NTF2-like | 0 | Direct |
ADP-ribosylation | 0 | Direct |
LDH C-terminal domain-like | 0 | Direct |
LDL receptor-like module | 0 | Direct |
Hairpin loop containing domain-like | 0 | Direct |
Formin homology 2 domain (FH2 domain) | 0 | Direct |
Single hybrid motif | 0 | Direct |
Galactose oxidase, central domain | 0 | Direct |
Supernatant protein factor (SPF), C-terminal domain | 0 | Direct |
Ribosomal protein L1 | 0 | Direct |
FAD-linked reductases, C-terminal domain | 0 | Direct |
PGBD-like | 0 | Direct |
Second domain of FERM | 0 | Direct |
MgtE membrane domain-like | 0 | Direct |
Tautomerase/MIF | 0 | Direct |
Ribosomal protein S10 | 0 | Direct |
Phosphoglucomutase, first 3 domains | 0 | Direct |
RCC1/BLIP-II | 0 | Direct |
Ferritin-like | 0 | Direct |
Tubby C-terminal domain-like | 0 | Direct |
Restriction endonuclease-like | 0 | Direct |
SWIB/MDM2 domain | 0 | Direct |
Chromo domain-like | 0 | Direct |
Cu,Zn superoxide dismutase-like | 0 | Direct |
Chitinase insertion domain | 0 | Direct |
Prefoldin | 0 | Direct |
Sema domain | 0 | Direct |
Zn-finger domain of Sec23/24 | 0 | Direct |
Oxysterol-binding protein-like | 0 | Direct |
PYP-like sensor domain (PAS domain) | 0 | Direct |
Myosin rod fragments | 0 | Direct |
t-snare proteins | 0 | Direct |
N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
Nudix | 0 | Direct |
DNA ligase/mRNA capping enzyme, catalytic domain | 0 | Direct |
MOSC N-terminal domain-like | 0 | Direct |
Cytidine deaminase-like | 0 | Direct |
Bactericidal permeability-increasing protein, BPI | 0 | Direct |
ABC transporter transmembrane region | 0 | Direct |
BolA-like | 0 | Direct |
PHM/PNGase F | 0 | Direct |
Cysteine-rich DNA binding domain, (DM domain) | 0 | Direct |
PABC (PABP) domain | 0 | Direct |
Clc chloride channel | 0 | Direct |
Phoshotransferase/anion transport protein | 0 | Direct |
FMN-linked oxidoreductases | 0 | Direct |
Kelch motif | 0 | Direct |
SAND domain-like | 0 | Direct |
GroES-like | 0 | Direct |
Creatinase/aminopeptidase | 0 | Direct |
Families 57/38 glycoside transferase middle domain | 0 | Direct |
Periplasmic binding protein-like I | 0 | Direct |
Ran binding protein zinc finger-like | 0 | Direct |
Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | Direct |
Calcium ATPase, transduction domain A | 0 | Direct |
Clathrin adaptor appendage domain | 0 | Direct |
FabD/lysophospholipase-like | 0 | Direct |
PRTase-like | 0 | Direct |
ENTH/VHS domain | 0 | Direct |
Spermadhesin, CUB domain | 0 | Direct |
FtsH protease domain-like | 0 | Direct |
SNARE-like | 0 | Direct |
ALDH-like | 0 | Direct |
B-box zinc-binding domain | 0 | Direct |
Phosphoglycerate mutase-like | 0 | Direct |
Alpha-L RNA-binding motif | 0 | Direct |
PurM N-terminal domain-like | 0 | Direct |
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | Direct |
Cysteine-rich domain | 0 | Direct |
HSP90 C-terminal domain | 0 | Direct |
CalX-like | 0 | Direct |
Glycoside hydrolase/deacetylase | 0 | Direct |
Translation proteins SH3-like domain | 0 | Direct |
Mob1/phocein | 0 | Direct |
DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
LysM domain | 0 | Direct |
Acyl-CoA N-acyltransferases (Nat) | 0 | Direct |
PreATP-grasp domain | 0 | Direct |
EF-G C-terminal domain-like | 0 | Direct |
Class II aaRS and biotin synthetases | 0 | Direct |
p53-like transcription factors | 0 | Direct |
HSP20-like chaperones | 0 | Direct |
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
Seven-hairpin glycosidases | 0 | Direct |
Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
Plexin repeat | 0 | Direct |
Thyroglobulin type-1 domain | 0 | Direct |
Domain of poly(ADP-ribose) polymerase | 0 | Direct |
Integrin alpha N-terminal domain | 0 | Direct |
Ypt/Rab-GAP domain of gyp1p | 0 | Direct |
ThrRS/AlaRS common domain | 0 | Direct |
DNA repair protein MutS, domain III | 0 | Direct |
SpoIIaa-like | 0 | Direct |
Amidase signature (AS) enzymes | 0 | Direct |
alpha-helical ferredoxin | 0 | Direct |
beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | Direct |
Polo-box domain | 0 | Direct |
Class I glutamine amidotransferase-like | 0 | Direct |
C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
MFPT repeat-like | 0 | Direct |
Tubulin C-terminal domain-like | 0 | Direct |
Regulator of G-protein signaling, RGS | 0 | Direct |
Cupredoxins | 0 | Direct |
CRAL/TRIO domain | 0 | Direct |
Phospholipase D/nuclease | 0 | Direct |
Troponin coil-coiled subunits | 0 | Direct |
Sec7 domain | 0 | Direct |
Inhibitor of apoptosis (IAP) repeat | 0 | Direct |
NagB/RpiA/CoA transferase-like | 0 | Direct |
Clavaminate synthase-like | 0 | Direct |
Molybdenum cofactor biosynthesis proteins | 0 | Direct |
Pepsin inhibitor-3 | 0 | Direct |
cAMP-binding domain-like | 0 | Direct |
PK beta-barrel domain-like | 0 | Direct |
ValRS/IleRS/LeuRS editing domain | 0 | Direct |
Cystatin/monellin | 0 | Direct |
Glutamine synthetase, N-terminal domain | 0 | Direct |
Molybdenum cofactor-binding domain | 0 | Direct |
GAT-like domain | 0 | Direct |
Multidrug resistance efflux transporter EmrE | 0 | Direct |
BSD domain-like | 0 | Direct |
SMAD/FHA domain | 0 | Direct |
Purple acid phosphatase, N-terminal domain | 0 | Direct |
GHMP Kinase, C-terminal domain | 0 | Direct |
F1F0 ATP synthase subunit C | 0 | Direct |
Concanavalin A-like lectins/glucanases | 0 | Direct |
R3H domain | 0 | Direct |
eIF4e-like | 0 | Direct |
Thiolase-like | 0 | Direct |
Ribosomal L27 protein-like | 0 | Direct |
Rhodanese/Cell cycle control phosphatase | 0 | Direct |
S-adenosylmethionine synthetase | 0 | Direct |
TIMP-like | 0 | Direct |
Ribosomal protein L10-like | 0 | Direct |
C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
Ribosomal proteins S24e, L23 and L15e | 0 | Direct |
Hect, E3 ligase catalytic domain | 0 | Direct |
Smc hinge domain | 0 | Direct |
Kringle-like | 0 | Direct |
HMG-box | 0 | Direct |
beta-sandwich domain of Sec23/24 | 0 | Direct |
Six-hairpin glycosidases | 0 | Direct |
CCCH zinc finger | 0 | Direct |
Leukotriene A4 hydrolase N-terminal domain | 0 | Direct |
L30e-like | 0 | Direct |
Adenine nucleotide alpha hydrolases-like | 0 | Direct |
Skp1 dimerisation domain-like | 0 | Direct |
NHL repeat | 0 | Direct |
3-carboxy-cis,cis-mucoante lactonizing enzyme | 0 | Direct |
Zinc beta-ribbon | 0 | Direct |
SH3-domain | 0 | Direct |
Ribosomal protein S18 | 0 | Direct |
Doublecortin (DC) | 0 | Direct |
Profilin (actin-binding protein) | 0 | Direct |
Pectin lyase-like | 0 | Direct |
UBA-like | 0 | Direct |
Rap/Ran-GAP | 0 | Direct |
Osmotin, thaumatin-like protein | 0 | Direct |
Heme-dependent peroxidases | 0 | Direct |
Serine protease inhibitors | 0 | Direct |
Invertebrate chitin-binding proteins | 0 | Direct |
Aminomethyltransferase beta-barrel domain | 0 | Direct |
Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
CBD9-like | 0 | Direct |
GYF domain | 0 | Direct |
Calponin-homology domain, CH-domain | 0 | Direct |
Actin-like ATPase domain | 0 | Direct |
Transducin (heterotrimeric G protein), gamma chain | 0 | Direct |
Diaminopimelate epimerase-like | 0 | Direct |
Transducin (alpha subunit), insertion domain | 0 | Direct |
SAICAR synthase-like | 0 | Direct |
Cyclophilin-like | 0 | Direct |
Nucleoporin domain | 0 | Direct |
Terpenoid cyclases/Protein prenyltransferases | 0 | Direct |
PEP carboxykinase-like | 0 | Direct |
Metallo-hydrolase/oxidoreductase | 0 | Direct |
Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
L domain-like | 0 | Direct |
HIT-like | 0 | Direct |
Alkaline phosphatase-like | 0 | Direct |
E2F-DP heterodimerization region | 0 | Direct |
Pseudouridine synthase | 0 | Direct |
Hypothetical protein c14orf129, hspc210 | 0 | Direct |
Multidrug efflux transporter AcrB transmembrane domain | 0 | Direct |
Nucleic acid-binding proteins | 0 | Direct |
N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0 | Direct |
Aldolase | 0 | Direct |
Immunoglobulin | 0 | Direct |
Isocitrate/Isopropylmalate dehydrogenase-like | 0 | Direct |
Mitochondrial carrier | 0 | Direct |
Cytochrome b5-like heme/steroid binding domain | 0 | Direct |
Cap-Gly domain | 0 | Direct |
Rudiment single hybrid motif | 0 | Direct |
Frizzled cysteine-rich domain | 0 | Direct |
YWTD domain | 0 | Direct |
RBP11-like subunits of RNA polymerase | 0 | Direct |
Protease propeptides/inhibitors | 0 | Direct |
SCP-like | 0 | Direct |
Ammonium transporter | 0 | Direct |
YbiA-like | 0 | Direct |
Citrate synthase | 0 | Direct |
GroEL equatorial domain-like | 0 | Direct |
DNase I-like | 0 | Direct |
eIF1-like | 0 | Direct |
KA1-like | 0 | Direct |
HD-domain/PDEase-like | 0 | Direct |
Actin depolymerizing proteins | 0 | Direct |
UBC-like | 0 | Direct |
CO dehydrogenase molybdoprotein N-domain-like | 0 | Direct |
Intermediate filament protein, coiled coil region | 0 | Direct |
Thioesterase/thiol ester dehydrase-isomerase | 0 | Direct |
Nucleotide-binding domain | 0 | Direct |
ADC-like | 0 | Direct |
PIN domain-like | 0 | Direct |
PurM C-terminal domain-like | 0 | Direct |
Lipocalins | 0 | Direct |
Glycerol-3-phosphate (1)-acyltransferase | 0 | Direct |
AraD/HMP-PK domain-like | 0 | Direct |
SPOC domain-like | 0 | Direct |
HLH, helix-loop-helix DNA-binding domain | 0 | Direct |
The spindle assembly checkpoint protein mad2 | 0 | Direct |
Activating enzymes of the ubiquitin-like proteins | 0 | Direct |
Blood coagulation inhibitor (disintegrin) | 0 | Direct |
Tropomyosin | 0 | Direct |
CRAL/TRIO N-terminal domain | 0 | Direct |
L-aspartase-like | 0 | Direct |
ARID-like | 0 | Direct |
HSP40/DnaJ peptide-binding domain | 0 | Direct |
Kix domain of CBP (creb binding protein) | 0 | Direct |
Glycosyl hydrolase domain | 0 | Direct |
Aquaporin-like | 0 | Direct |
Calpain large subunit, middle domain (domain III) | 0 | Direct |
Composite domain of metallo-dependent hydrolases | 0 | Direct |
Sm-like ribonucleoproteins | 0 | Direct |
VPS9 domain | 0 | Direct |
Periplasmic binding protein-like II | 0 | Direct |
LEM domain | 0 | Direct |
Proton glutamate symport protein | 0 | Direct |
Class II aaRS ABD-related | 0 | Direct |
Complement control module/SCR domain | 0 | Direct |
Fibronectin type III | 0 | Direct |
Fibrinogen C-terminal domain-like | 0 | Direct |
Cation efflux protein cytoplasmic domain-like | 0 | Direct |
Carbon-nitrogen hydrolase | 0 | Direct |
TAZ domain | 0 | Direct |
FAD-binding/transporter-associated domain-like | 0 | Direct |
lambda repressor-like DNA-binding domains | 0 | Direct |
Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
Growth factor receptor domain | 0 | Direct |
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0 | Direct |
Thiamin diphosphate-binding fold (THDP-binding) | 0 | Direct |
Small-conductance potassium channel | 0 | Direct |
Guanido kinase N-terminal domain | 0 | Direct |
HIT/MYND zinc finger-like | 0 | Direct |
Creatinase/prolidase N-terminal domain | 0 | Direct |
GroEL-intermediate domain like | 0 | Direct |
PH domain-like | 0 | Direct |
Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | Direct |
SAP domain | 0 | Direct |
Folate-binding domain | 0 | Direct |
HRDC-like | 0 | Direct |
GAS2 domain-like | 0 | Direct |
Acid phosphatase/Vanadium-dependent haloperoxidase | 0 | Direct |
BEACH domain | 0 | Direct |
Ribonuclease PH domain 2-like | 0 | Direct |
Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | Direct |
PEBP-like | 0 | Direct |
6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | Direct |
PAP/OAS1 substrate-binding domain | 0 | Direct |
Outer arm dynein light chain 1 | 0 | Direct |
2Fe-2S ferredoxin-like | 0 | Direct |
ISP domain | 0 | Direct |
Bacterial exopeptidase dimerisation domain | 0 | Direct |
PLC-like phosphodiesterases | 0 | Direct |
Rhomboid-like | 0 | Direct |
Cation efflux protein transmembrane domain-like | 0 | Direct |
SNARE fusion complex | 0 | Direct |
RmlC-like cupins | 0 | Direct |
beta-lactamase/transpeptidase-like | 0 | Direct |
Aminoacid dehydrogenase-like, N-terminal domain | 0 | Direct |
ClpP/crotonase | 0 | Direct |
Ankyrin repeat | 0 | Direct |
Elafin-like | 0 | Direct |
Chaperone J-domain | 0 | Direct |
Putative DNA-binding domain | 0 | Direct |
SAM/Pointed domain | 0 | Direct |
Formate/glycerate dehydrogenase catalytic domain-like | 0 | Direct |
BPTI-like | 0 | Direct |
WGR domain-like | 0 | Direct |
Translation proteins | 0 | Direct |
Lysozyme-like | 0 | Direct |
NAD(P)-linked oxidoreductase | 0 | Direct |
Acid proteases | 0 | Direct |
Di-copper centre-containing domain | 0 | Direct |
alpha/beta knot | 0 | Direct |
vWA-like | 0 | Direct |
Transcription factor IIA (TFIIA), alpha-helical domain | 0 | Direct |
4Fe-4S ferredoxins | 0 | Direct |
Tubulin nucleotide-binding domain-like | 0 | Direct |
BAR/IMD domain-like | 0 | Direct |
Roadblock/LC7 domain | 0 | Direct |
Arginase/deacetylase | 0 | Direct |
Pentein | 0 | Direct |
Mss4-like | 0 | Direct |
Eukaryotic type KH-domain (KH-domain type I) | 0 | Direct |
PP2C-like | 0 | Direct |
Riboflavin synthase domain-like | 0 | Direct |
Nucleotidyltransferase | 0 | Direct |
Retrovirus zinc finger-like domains | 0 | Direct |
Integrin domains | 0 | Direct |
SGNH hydrolase | 0 | Direct |
Tudor/PWWP/MBT | 0 | Direct |
Ras GEF | 0 | Direct |
BRCT domain | 0 | Direct |
FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | Direct |
SIS domain | 0 | Direct |
MIT domain | 0 | Direct |
RuvA domain 2-like | 0 | Direct |
CO dehydrogenase ISP C-domain like | 0 | Direct |
Metal cation-transporting ATPase, ATP-binding domain N | 0 | Direct |
Carbonic anhydrase | 0 | Direct |
Cystine-knot cytokines | 0 | Direct |
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | Direct |
Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
TGS-like | 0 | Direct |
Sec1/munc18-like (SM) proteins | 0 | Direct |
Annexin | 0 | Direct |
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
Terpenoid synthases | 0 | Direct |
14-3-3 protein | 0 | Direct |
Carbohydrate phosphatase | 0 | Direct |
S-adenosyl-L-methionine-dependent methyltransferases | 0 | Direct |
Lipovitellin-phosvitin complex, superhelical domain | 0 | Direct |
Tim10-like | 0 | Direct |
DNA clamp | 0 | Direct |
HAD-like | 0 | Direct |
DPP6 N-terminal domain-like | 0 | Direct |
PLP-binding barrel | 0 | Direct |
PX domain | 0 | Direct |
Acyl-CoA binding protein | 0 | Direct |
Carboxypeptidase regulatory domain-like | 0 | Direct |
Actin-crosslinking proteins | 0 | Direct |
Phospholipase A2, PLA2 | 0 | Direct |
CBS-domain pair | 0 | Direct |
Nucleotide-diphospho-sugar transferases | 0 | Direct |
Translational machinery components | 0 | Direct |
Nucleotide cyclase | 0 | Direct |
Sec63 N-terminal domain-like | 0 | Direct |
Calcium ATPase, transmembrane domain M | 0 | Direct |
Subtilisin-like | 0 | Direct |
Glycolipid transfer protein, GLTP | 0 | Direct |
PR-1-like | 0 | Direct |
Succinyl-CoA synthetase domains | 0 | Direct |
Cytochrome c | 0 | Direct |
Heme-dependent catalase-like | 0 | Direct |
SMR domain-like | 0 | Direct |
FAD-linked oxidases, C-terminal domain | 0 | Direct |
ARM repeat | 0.0719 | Inherited |
RNA-binding domain, RBD | 0.195 | Inherited |
PapD-like | 0.231 | Inherited |
Nicotinic receptor ligand binding domain-like | 0.2577 | Inherited |
Voltage-gated potassium channels | 0.3048 | Inherited |
Neurotransmitter-gated ion-channel transmembrane pore | 0.3094 | Inherited |
Ubiquitin-like | 0.3495 | Inherited |
Metallo-dependent phosphatases | 0.4155 | Inherited |
FYVE/PHD zinc finger | 0.5098 | Inherited |
EF-hand | 0.6033 | Inherited |
WD40 repeat-like | 0.6454 | Inherited |
TPR-like | 0.6671 | Inherited |
GTPase activation domain, GAP | 0.7197 | Inherited |
P-loop containing nucleoside triphosphate hydrolases | 0.7215 | Inherited |
Saposin | 0.7714 | Inherited |
(Phosphotyrosine protein) phosphatases II | 0.8038 | Inherited |
"Winged helix" DNA-binding domain | 0.8739 | Inherited |
RING/U-box | 0.895 | Inherited |
Lamin A/C globular tail domain | 0.9336 | Inherited |
PLP-dependent transferases | 0.9409 | Inherited |
SH2 domain | 1 | Inherited |
Protein kinase-like (PK-like) | 1 | Inherited |
(show details)
Supra-domains annotated to this WP term (Not in SPWP)
Highlighted in gray are those with FDR>0.001
Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
56112,82615 56112 - Protein kinase-like (PK-like) 82615 - Polo-box domain | 0 | DIRECT |
82919,53300 82919 - Zn-finger domain of Sec23/24 53300 - vWA-like | 0 | DIRECT |
50156,50044 50156 - PDZ domain-like 50044 - SH3-domain | 0 | DIRECT |
81324,81296 81324 - Voltage-gated potassium channels 81296 - E set domains | 0 | DIRECT |
54236,47031 54236 - Ubiquitin-like 47031 - Second domain of FERM | 0 | DIRECT |
48179,48179 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | DIRECT |
56024,56024 56024 - Phospholipase D/nuclease 56024 - Phospholipase D/nuclease | 0 | DIRECT |
56176,55103 56176 - FAD-binding/transporter-associated domain-like 55103 - FAD-linked oxidases, C-terminal domain | 0 | DIRECT |
51905,56425 51905 - FAD/NAD(P)-binding domain 56425 - Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | DIRECT |
161093,161093 161093 - MgtE membrane domain-like 161093 - MgtE membrane domain-like | 0 | DIRECT |
52540,90123 52540 - P-loop containing nucleoside triphosphate hydrolases 90123 - ABC transporter transmembrane region | 0 | DIRECT |
101690,53098 101690 - PAZ domain 53098 - Ribonuclease H-like | 0 | DIRECT |
51445,51011 51445 - (Trans)glycosidases 51011 - Glycosyl hydrolase domain | 0 | DIRECT |
50249,50249 50249 - Nucleic acid-binding proteins 50249 - Nucleic acid-binding proteins | 0 | DIRECT |
48334,52540 48334 - DNA repair protein MutS, domain III 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
46785,144074 46785 - "Winged helix" DNA-binding domain 144074 - E2F-DP heterodimerization region | 0 | DIRECT |
141739,141739 141739 - MFPT repeat-like 141739 - MFPT repeat-like | 0 | DIRECT |
55753,55753 55753 - Actin depolymerizing proteins 55753 - Actin depolymerizing proteins | 0 | DIRECT |
54495,46934 54495 - UBC-like 46934 - UBA-like | 0 | DIRECT |
46966,46966 46966 - Spectrin repeat 46966 - Spectrin repeat | 0 | DIRECT |
50156,50156 50156 - PDZ domain-like 50156 - PDZ domain-like | 0 | DIRECT |
54695,81382 54695 - POZ domain 81382 - Skp1 dimerisation domain-like | 0 | DIRECT |
141072,141072 141072 - CalX-like 141072 - CalX-like | 0 | DIRECT |
48371,56112 48371 - ARM repeat 56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
57196,63825 57196 - EGF/Laminin 63825 - YWTD domain | 0 | DIRECT |
51735,56327 51735 - NAD(P)-binding Rossmann-fold domains 56327 - LDH C-terminal domain-like | 0 | DIRECT |
51735,48179 51735 - NAD(P)-binding Rossmann-fold domains 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | DIRECT |
52490,55307 52490 - Tubulin nucleotide-binding domain-like 55307 - Tubulin C-terminal domain-like | 0 | DIRECT |
64356,49447 64356 - SNARE-like 49447 - Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
46938,52087 46938 - CRAL/TRIO N-terminal domain 52087 - CRAL/TRIO domain | 0 | DIRECT |
53738,55957 53738 - Phosphoglucomutase, first 3 domains 55957 - Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
48065,50729 48065 - DBL homology domain (DH-domain) 50729 - PH domain-like | 0 | DIRECT |
57567,57567 57567 - Serine protease inhibitors 57567 - Serine protease inhibitors | 0 | DIRECT |
48403,48403 48403 - Ankyrin repeat 48403 - Ankyrin repeat | 0 | DIRECT |
90257,90257 90257 - Myosin rod fragments 90257 - Myosin rod fragments | 0 | DIRECT |
53448,50370 53448 - Nucleotide-diphospho-sugar transferases 50370 - Ricin B-like lectins | 0 | DIRECT |
56091,50249 56091 - DNA ligase/mRNA capping enzyme, catalytic domain 50249 - Nucleic acid-binding proteins | 0 | DIRECT |
49854,49854 49854 - Spermadhesin, CUB domain 49854 - Spermadhesin, CUB domain | 0 | DIRECT |
56112,48371 56112 - Protein kinase-like (PK-like) 48371 - ARM repeat | 0 | DIRECT |
51126,51126 51126 - Pectin lyase-like 51126 - Pectin lyase-like | 0 | DIRECT |
52540,81271 52540 - P-loop containing nucleoside triphosphate hydrolases 81271 - TGS-like | 0 | DIRECT |
64593,74853 64593 - Intermediate filament protein, coiled coil region 74853 - Lamin A/C globular tail domain | 0 | DIRECT |
101912,103575 101912 - Sema domain 103575 - Plexin repeat | 0 | DIRECT |
52833,52833 52833 - Thioredoxin-like 52833 - Thioredoxin-like | 0 | DIRECT |
52113,52113 52113 - BRCT domain 52113 - BRCT domain | 0 | DIRECT |
52374,47323 52374 - Nucleotidylyl transferase 47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
50729,47473 50729 - PH domain-like 47473 - EF-hand | 0 | DIRECT |
57889,50729 57889 - Cysteine-rich domain 50729 - PH domain-like | 0 | DIRECT |
57903,82199 57903 - FYVE/PHD zinc finger 82199 - SET domain | 0 | DIRECT |
51206,51206 51206 - cAMP-binding domain-like 51206 - cAMP-binding domain-like | 0 | DIRECT |
55486,49854 55486 - Metalloproteases ("zincins"), catalytic domain 49854 - Spermadhesin, CUB domain | 0 | DIRECT |
57716,57716 57716 - Glucocorticoid receptor-like (DNA-binding domain) 57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0 | DIRECT |
50978,50978 50978 - WD40 repeat-like 50978 - WD40 repeat-like | 0 | DIRECT |
47031,50729 47031 - Second domain of FERM 50729 - PH domain-like | 0 | DIRECT |
47473,51695 47473 - EF-hand 51695 - PLC-like phosphodiesterases | 0 | DIRECT |
47741,56176 47741 - CO dehydrogenase ISP C-domain like 56176 - FAD-binding/transporter-associated domain-like | 0 | DIRECT |
57903,57903 57903 - FYVE/PHD zinc finger 57903 - FYVE/PHD zinc finger | 0 | DIRECT |
55486,57552 55486 - Metalloproteases ("zincins"), catalytic domain 57552 - Blood coagulation inhibitor (disintegrin) | 0 | DIRECT |
56112,56112 56112 - Protein kinase-like (PK-like) 56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
52374,52374 52374 - Nucleotidylyl transferase 52374 - Nucleotidylyl transferase | 0 | DIRECT |
52743,49785 52743 - Subtilisin-like 49785 - Galactose-binding domain-like | 0 | DIRECT |
54211,55060 54211 - Ribosomal protein S5 domain 2-like 55060 - GHMP Kinase, C-terminal domain | 0 | DIRECT |
56112,55073 56112 - Protein kinase-like (PK-like) 55073 - Nucleotide cyclase | 0 | DIRECT |
49742,49742 49742 - PHM/PNGase F 49742 - PHM/PNGase F | 0 | DIRECT |
47954,47954 47954 - Cyclin-like 47954 - Cyclin-like | 0 | DIRECT |
52518,52922 52518 - Thiamin diphosphate-binding fold (THDP-binding) 52922 - TK C-terminal domain-like | 0 | DIRECT |
48371,48371 48371 - ARM repeat 48371 - ARM repeat | 0 | DIRECT |
47576,47576 47576 - Calponin-homology domain, CH-domain 47576 - Calponin-homology domain, CH-domain | 0 | DIRECT |
54928,54928 54928 - RNA-binding domain, RBD 54928 - RNA-binding domain, RBD | 0 | DIRECT |
57196,57196 57196 - EGF/Laminin 57196 - EGF/Laminin | 0 | DIRECT |
82615,82615 82615 - Polo-box domain 82615 - Polo-box domain | 0 | DIRECT |
55973,55973 55973 - S-adenosylmethionine synthetase 55973 - S-adenosylmethionine synthetase | 0 | DIRECT |
55785,55785 55785 - PYP-like sensor domain (PAS domain) 55785 - PYP-like sensor domain (PAS domain) | 0 | DIRECT |
48726,48726 48726 - Immunoglobulin 48726 - Immunoglobulin | 0 | DIRECT |
46689,46689 46689 - Homeodomain-like 46689 - Homeodomain-like | 0 | DIRECT |
54495,57850 54495 - UBC-like 57850 - RING/U-box | 0 | DIRECT |
53901,53901 53901 - Thiolase-like 53901 - Thiolase-like | 0 | DIRECT |
57362,57362 57362 - BPTI-like 57362 - BPTI-like | 0 | DIRECT |
56968,48431 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions 48431 - Lipovitellin-phosvitin complex, superhelical domain | 0 | DIRECT |
56059,52210 56059 - Glutathione synthetase ATP-binding domain-like 52210 - Succinyl-CoA synthetase domains | 0 | DIRECT |
49363,56300 49363 - Purple acid phosphatase, N-terminal domain 56300 - Metallo-dependent phosphatases | 0 | DIRECT |
63380,52343 63380 - Riboflavin synthase domain-like 52343 - Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | DIRECT |
68923,53795 68923 - PEP carboxykinase N-terminal domain 53795 - PEP carboxykinase-like | 0 | DIRECT |
52047,52047 52047 - RNI-like 52047 - RNI-like | 0 | DIRECT |
52440,56059 52440 - PreATP-grasp domain 56059 - Glutathione synthetase ATP-binding domain-like | 0 | DIRECT |
50677,52374 50677 - ValRS/IleRS/LeuRS editing domain 52374 - Nucleotidylyl transferase | 0 | DIRECT |
57196,49899 57196 - EGF/Laminin 49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
52540,46785 52540 - P-loop containing nucleoside triphosphate hydrolases 46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
82895,82895 82895 - TSP-1 type 1 repeat 82895 - TSP-1 type 1 repeat | 0 | DIRECT |
81301,81631 81301 - Nucleotidyltransferase 81631 - PAP/OAS1 substrate-binding domain | 0 | DIRECT |
50692,54585 50692 - ADC-like 54585 - Cdc48 domain 2-like | 0 | DIRECT |
54001,49758 54001 - Cysteine proteinases 49758 - Calpain large subunit, middle domain (domain III) | 0 | DIRECT |
52799,52799 52799 - (Phosphotyrosine protein) phosphatases II 52799 - (Phosphotyrosine protein) phosphatases II | 0 | DIRECT |
57535,57535 57535 - Complement control module/SCR domain 57535 - Complement control module/SCR domain | 0 | DIRECT |
50447,54980 50447 - Translation proteins 54980 - EF-G C-terminal domain-like | 0 | DIRECT |
81660,56784 81660 - Metal cation-transporting ATPase, ATP-binding domain N 56784 - HAD-like | 0 | DIRECT |
55550,50044 55550 - SH2 domain 50044 - SH3-domain | 0 | DIRECT |
57863,48403 57863 - ArfGap/RecO-like zinc finger 48403 - Ankyrin repeat | 0 | DIRECT |
51971,54373 51971 - Nucleotide-binding domain 54373 - FAD-linked reductases, C-terminal domain | 0 | DIRECT |
47769,47769 47769 - SAM/Pointed domain 47769 - SAM/Pointed domain | 0 | DIRECT |
49562,49562 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
81383,52047 81383 - F-box domain 52047 - RNI-like | 0 | DIRECT |
54211,54980 54211 - Ribosomal protein S5 domain 2-like 54980 - EF-G C-terminal domain-like | 0 | DIRECT |
49899,49899 49899 - Concanavalin A-like lectins/glucanases 49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
81698,81698 81698 - FF domain 81698 - FF domain | 0 | DIRECT |
63737,55486 63737 - Leukotriene A4 hydrolase N-terminal domain 55486 - Metalloproteases ("zincins"), catalytic domain | 0 | DIRECT |
117281,117281 117281 - Kelch motif 117281 - Kelch motif | 0 | DIRECT |
48726,49265 48726 - Immunoglobulin 49265 - Fibronectin type III | 0 | DIRECT |
53067,100920 53067 - Actin-like ATPase domain 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
48592,54849 48592 - GroEL equatorial domain-like 54849 - GroEL-intermediate domain like | 0 | DIRECT |
57184,57196 57184 - Growth factor receptor domain 57196 - EGF/Laminin | 0 | DIRECT |
51338,51556 51338 - Composite domain of metallo-dependent hydrolases 51556 - Metallo-dependent hydrolases | 0 | DIRECT |
47413,46689 47413 - lambda repressor-like DNA-binding domains 46689 - Homeodomain-like | 0 | DIRECT |
50044,50044 50044 - SH3-domain 50044 - SH3-domain | 0 | DIRECT |
57414,57414 57414 - Hairpin loop containing domain-like 57414 - Hairpin loop containing domain-like | 0 | DIRECT |
55729,55729 55729 - Acyl-CoA N-acyltransferases (Nat) 55729 - Acyl-CoA N-acyltransferases (Nat) | 0 | DIRECT |
54368,55931 54368 - Glutamine synthetase, N-terminal domain 55931 - Glutamine synthetase/guanido kinase | 0 | DIRECT |
55486,50923 55486 - Metalloproteases ("zincins"), catalytic domain 50923 - Hemopexin-like domain | 0 | DIRECT |
51445,54556 51445 - (Trans)glycosidases 54556 - Chitinase insertion domain | 0 | DIRECT |
51905,55424 51905 - FAD/NAD(P)-binding domain 55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | DIRECT |
50729,56112 50729 - PH domain-like 56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
49493,49493 49493 - HSP40/DnaJ peptide-binding domain 49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
47895,52540 47895 - Transducin (alpha subunit), insertion domain 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
103025,101790 103025 - Folate-binding domain 101790 - Aminomethyltransferase beta-barrel domain | 0 | DIRECT |
51905,54373 51905 - FAD/NAD(P)-binding domain 54373 - FAD-linked reductases, C-terminal domain | 0 | DIRECT |
88713,88688 88713 - Glycoside hydrolase/deacetylase 88688 - Families 57/38 glycoside transferase middle domain | 0 | DIRECT |
56645,47203 56645 - Acyl-CoA dehydrogenase NM domain-like 47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
100950,100950 100950 - NagB/RpiA/CoA transferase-like 100950 - NagB/RpiA/CoA transferase-like | 0 | DIRECT |
48431,56968 48431 - Lipovitellin-phosvitin complex, superhelical domain 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | DIRECT |
52540,47917 52540 - P-loop containing nucleoside triphosphate hydrolases 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
54160,52540 54160 - Chromo domain-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
51695,49562 51695 - PLC-like phosphodiesterases 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
90123,52540 90123 - ABC transporter transmembrane region 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
51905,51905 51905 - FAD/NAD(P)-binding domain 51905 - FAD/NAD(P)-binding domain | 0 | DIRECT |
90229,90229 90229 - CCCH zinc finger 90229 - CCCH zinc finger | 0 | DIRECT |
57850,57845 57850 - RING/U-box 57845 - B-box zinc-binding domain | 0 | DIRECT |
48425,50729 48425 - Sec7 domain 50729 - PH domain-like | 0 | DIRECT |
49313,49313 49313 - Cadherin-like 49313 - Cadherin-like | 0 | DIRECT |
46785,46785 46785 - "Winged helix" DNA-binding domain 46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
57889,48350 57889 - Cysteine-rich domain 48350 - GTPase activation domain, GAP | 0 | DIRECT |
49599,54695 49599 - TRAF domain-like 54695 - POZ domain | 0 | DIRECT |
55326,56042 55326 - PurM N-terminal domain-like 56042 - PurM C-terminal domain-like | 0 | DIRECT |
49265,48726 49265 - Fibronectin type III 48726 - Immunoglobulin | 0 | DIRECT |
54211,55666 54211 - Ribosomal protein S5 domain 2-like 55666 - Ribonuclease PH domain 2-like | 0 | DIRECT |
49562,48371 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) 48371 - ARM repeat | 0 | DIRECT |
47203,47203 47203 - Acyl-CoA dehydrogenase C-terminal domain-like 47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
50044,55550 50044 - SH3-domain 55550 - SH2 domain | 0 | DIRECT |
53738,53738 53738 - Phosphoglucomutase, first 3 domains 53738 - Phosphoglucomutase, first 3 domains | 0 | DIRECT |
53187,49464 53187 - Zn-dependent exopeptidases 49464 - Carboxypeptidase regulatory domain-like | 0 | DIRECT |
51735,55347 51735 - NAD(P)-binding Rossmann-fold domains 55347 - Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | DIRECT |
81383,50978 81383 - F-box domain 50978 - WD40 repeat-like | 0 | DIRECT |
57850,57850 57850 - RING/U-box 57850 - RING/U-box | 0 | DIRECT |
52518,52518 52518 - Thiamin diphosphate-binding fold (THDP-binding) 52518 - Thiamin diphosphate-binding fold (THDP-binding) | 0 | DIRECT |
51045,51045 51045 - WW domain 51045 - WW domain | 0 | DIRECT |
54897,53187 54897 - Protease propeptides/inhibitors 53187 - Zn-dependent exopeptidases | 0 | DIRECT |
52058,52058 52058 - L domain-like 52058 - L domain-like | 0 | DIRECT |
57196,57184 57196 - EGF/Laminin 57184 - Growth factor receptor domain | 0 | DIRECT |
47587,56399 47587 - Domain of poly(ADP-ribose) polymerase 56399 - ADP-ribosylation | 0 | DIRECT |
54534,54534 54534 - FKBP-like 54534 - FKBP-like | 0 | DIRECT |
144232,82199 144232 - HIT/MYND zinc finger-like 82199 - SET domain | 0 | DIRECT |
50129,51735 50129 - GroES-like 51735 - NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
54160,54160 54160 - Chromo domain-like 54160 - Chromo domain-like | 0 | DIRECT |
48403,52151 48403 - Ankyrin repeat 52151 - FabD/lysophospholipase-like | 0 | DIRECT |
81324,53850 81324 - Voltage-gated potassium channels 53850 - Periplasmic binding protein-like II | 0 | DIRECT |
48464,89009 48464 - ENTH/VHS domain 89009 - GAT-like domain | 0 | DIRECT |
74650,51445 74650 - Galactose mutarotase-like 51445 - (Trans)glycosidases | 0 | DIRECT |
53187,55031 53187 - Zn-dependent exopeptidases 55031 - Bacterial exopeptidase dimerisation domain | 0 | DIRECT |
54637,54637 54637 - Thioesterase/thiol ester dehydrase-isomerase 54637 - Thioesterase/thiol ester dehydrase-isomerase | 0 | DIRECT |
47473,103506 47473 - EF-hand 103506 - Mitochondrial carrier | 0 | DIRECT |
54236,54236 54236 - Ubiquitin-like 54236 - Ubiquitin-like | 0 | DIRECT |
81333,81333 81333 - F1F0 ATP synthase subunit C 81333 - F1F0 ATP synthase subunit C | 0 | DIRECT |
57756,57756 57756 - Retrovirus zinc finger-like domains 57756 - Retrovirus zinc finger-like domains | 0 | DIRECT |
52087,101576 52087 - CRAL/TRIO domain 101576 - Supernatant protein factor (SPF), C-terminal domain | 0 | DIRECT |
56601,48403 56601 - beta-lactamase/transpeptidase-like 48403 - Ankyrin repeat | 0 | DIRECT |
54665,56003 54665 - CO dehydrogenase molybdoprotein N-domain-like 56003 - Molybdenum cofactor-binding domain | 0 | DIRECT |
54897,52743 54897 - Protease propeptides/inhibitors 52743 - Subtilisin-like | 0 | DIRECT |
54849,52029 54849 - GroEL-intermediate domain like 52029 - GroEL apical domain-like | 0 | DIRECT |
54980,54211 54980 - EF-G C-terminal domain-like 54211 - Ribosomal protein S5 domain 2-like | 0 | DIRECT |
53067,53067 53067 - Actin-like ATPase domain 53067 - Actin-like ATPase domain | 0 | DIRECT |
52283,51735 52283 - Formate/glycerate dehydrogenase catalytic domain-like 51735 - NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
49265,49265 49265 - Fibronectin type III 49265 - Fibronectin type III | 0 | DIRECT |
100920,100934 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
50249,55681 50249 - Nucleic acid-binding proteins 55681 - Class II aaRS and biotin synthetases | 0 | DIRECT |
56436,49854 56436 - C-type lectin-like 49854 - Spermadhesin, CUB domain | 0 | DIRECT |
48403,52113 48403 - Ankyrin repeat 52113 - BRCT domain | 0 | DIRECT |
161111,160240 161111 - Cation efflux protein transmembrane domain-like 160240 - Cation efflux protein cytoplasmic domain-like | 0 | DIRECT |
141673,50800 141673 - MOSC N-terminal domain-like 50800 - PK beta-barrel domain-like | 0 | DIRECT |
47220,47220 47220 - alpha-catenin/vinculin-like 47220 - alpha-catenin/vinculin-like | 0 | DIRECT |
81296,81296 81296 - E set domains 81296 - E set domains | 0 | DIRECT |
54631,54631 54631 - CBS-domain pair 54631 - CBS-domain pair | 0 | DIRECT |
82171,53474 82171 - DPP6 N-terminal domain-like 53474 - alpha/beta-Hydrolases | 0 | DIRECT |
50447,50465 50447 - Translation proteins 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
52821,52821 52821 - Rhodanese/Cell cycle control phosphatase 52821 - Rhodanese/Cell cycle control phosphatase | 0 | DIRECT |
57938,49493 57938 - DnaJ/Hsp40 cysteine-rich domain 49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
55681,52954 55681 - Class II aaRS and biotin synthetases 52954 - Class II aaRS ABD-related | 0 | DIRECT |
52540,140990 52540 - P-loop containing nucleoside triphosphate hydrolases 140990 - FtsH protease domain-like | 0 | DIRECT |
49348,55711 49348 - Clathrin adaptor appendage domain 55711 - Subdomain of clathrin and coatomer appendage domain | 0 | DIRECT |
54791,54791 54791 - Eukaryotic type KH-domain (KH-domain type I) 54791 - Eukaryotic type KH-domain (KH-domain type I) | 0 | DIRECT |
47923,47923 47923 - Ypt/Rab-GAP domain of gyp1p 47923 - Ypt/Rab-GAP domain of gyp1p | 0 | DIRECT |
52540,50447 52540 - P-loop containing nucleoside triphosphate hydrolases 50447 - Translation proteins | 0 | DIRECT |
54292,47741 54292 - 2Fe-2S ferredoxin-like 47741 - CO dehydrogenase ISP C-domain like | 0 | DIRECT |
57184,57184 57184 - Growth factor receptor domain 57184 - Growth factor receptor domain | 0 | DIRECT |
51556,51338 51556 - Metallo-dependent hydrolases 51338 - Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
57889,57889 57889 - Cysteine-rich domain 57889 - Cysteine-rich domain | 0 | DIRECT |
50044,52540 50044 - SH3-domain 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
47090,55486 47090 - PGBD-like 55486 - Metalloproteases ("zincins"), catalytic domain | 0 | DIRECT |
57424,57424 57424 - LDL receptor-like module 57424 - LDL receptor-like module | 0 | DIRECT |
56784,81665 56784 - HAD-like 81665 - Calcium ATPase, transmembrane domain M | 0 | DIRECT |
57903,51197 57903 - FYVE/PHD zinc finger 51197 - Clavaminate synthase-like | 0 | DIRECT |
103473,100895 103473 - MFS general substrate transporter 100895 - Kazal-type serine protease inhibitors | 0 | DIRECT |
54585,52540 54585 - Cdc48 domain 2-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
49599,49599 49599 - TRAF domain-like 49599 - TRAF domain-like | 0 | DIRECT |
81811,82754 81811 - Helical domain of Sec23/24 82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
55920,46785 55920 - Creatinase/aminopeptidase 46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
81324,81327 81324 - Voltage-gated potassium channels 81327 - Small-conductance potassium channel | 0 | DIRECT |
52777,52777 52777 - CoA-dependent acyltransferases 52777 - CoA-dependent acyltransferases | 0 | DIRECT |
53300,53300 53300 - vWA-like 53300 - vWA-like | 0 | DIRECT |
48034,55931 48034 - Guanido kinase N-terminal domain 55931 - Glutamine synthetase/guanido kinase | 0 | DIRECT |
50978,50998 50978 - WD40 repeat-like 50998 - Quinoprotein alcohol dehydrogenase-like | 0 | DIRECT |
57850,117839 57850 - RING/U-box 117839 - WWE domain | 0 | DIRECT |
56672,100879 56672 - DNA/RNA polymerases 100879 - Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
55394,55394 55394 - Bactericidal permeability-increasing protein, BPI 55394 - Bactericidal permeability-increasing protein, BPI | 0 | DIRECT |
56059,51246 56059 - Glutathione synthetase ATP-binding domain-like 51246 - Rudiment single hybrid motif | 0 | DIRECT |
57625,57625 57625 - Invertebrate chitin-binding proteins 57625 - Invertebrate chitin-binding proteins | 0 | DIRECT |
53300,56436 53300 - vWA-like 56436 - C-type lectin-like | 0 | DIRECT |
63712,90112 63712 - Nicotinic receptor ligand binding domain-like 90112 - Neurotransmitter-gated ion-channel transmembrane pore | 0.3094 | INHERITED FROM: coelomic system physiology variant || coelomocyte uptake defective || coelomocyte physiology variant || transmission of nerve impulse variant || nervous system physiology variant || synaptic transmission variant |
57667,57667 57667 - beta-beta-alpha zinc fingers 57667 - beta-beta-alpha zinc fingers | 0.9039 | INHERITED FROM: alae secretion variant |
55550,56112 55550 - SH2 domain 56112 - Protein kinase-like (PK-like) | 1 | INHERITED FROM: muscle cell attachment variant |
Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
56112,82615 56112 - Protein kinase-like (PK-like) 82615 - Polo-box domain | 0 | Direct |
82919,53300 82919 - Zn-finger domain of Sec23/24 53300 - vWA-like | 0 | Direct |
50156,50044 50156 - PDZ domain-like 50044 - SH3-domain | 0 | Direct |
81324,81296 81324 - Voltage-gated potassium channels 81296 - E set domains | 0 | Direct |
54236,47031 54236 - Ubiquitin-like 47031 - Second domain of FERM | 0 | Direct |
48179,48179 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | Direct |
56024,56024 56024 - Phospholipase D/nuclease 56024 - Phospholipase D/nuclease | 0 | Direct |
56176,55103 56176 - FAD-binding/transporter-associated domain-like 55103 - FAD-linked oxidases, C-terminal domain | 0 | Direct |
51905,56425 51905 - FAD/NAD(P)-binding domain 56425 - Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | Direct |
161093,161093 161093 - MgtE membrane domain-like 161093 - MgtE membrane domain-like | 0 | Direct |
52540,90123 52540 - P-loop containing nucleoside triphosphate hydrolases 90123 - ABC transporter transmembrane region | 0 | Direct |
101690,53098 101690 - PAZ domain 53098 - Ribonuclease H-like | 0 | Direct |
51445,51011 51445 - (Trans)glycosidases 51011 - Glycosyl hydrolase domain | 0 | Direct |
50249,50249 50249 - Nucleic acid-binding proteins 50249 - Nucleic acid-binding proteins | 0 | Direct |
48334,52540 48334 - DNA repair protein MutS, domain III 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
46785,144074 46785 - "Winged helix" DNA-binding domain 144074 - E2F-DP heterodimerization region | 0 | Direct |
141739,141739 141739 - MFPT repeat-like 141739 - MFPT repeat-like | 0 | Direct |
55753,55753 55753 - Actin depolymerizing proteins 55753 - Actin depolymerizing proteins | 0 | Direct |
54495,46934 54495 - UBC-like 46934 - UBA-like | 0 | Direct |
46966,46966 46966 - Spectrin repeat 46966 - Spectrin repeat | 0 | Direct |
50156,50156 50156 - PDZ domain-like 50156 - PDZ domain-like | 0 | Direct |
54695,81382 54695 - POZ domain 81382 - Skp1 dimerisation domain-like | 0 | Direct |
141072,141072 141072 - CalX-like 141072 - CalX-like | 0 | Direct |
48371,56112 48371 - ARM repeat 56112 - Protein kinase-like (PK-like) | 0 | Direct |
57196,63825 57196 - EGF/Laminin 63825 - YWTD domain | 0 | Direct |
51735,56327 51735 - NAD(P)-binding Rossmann-fold domains 56327 - LDH C-terminal domain-like | 0 | Direct |
51735,48179 51735 - NAD(P)-binding Rossmann-fold domains 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | Direct |
52490,55307 52490 - Tubulin nucleotide-binding domain-like 55307 - Tubulin C-terminal domain-like | 0 | Direct |
64356,49447 64356 - SNARE-like 49447 - Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
46938,52087 46938 - CRAL/TRIO N-terminal domain 52087 - CRAL/TRIO domain | 0 | Direct |
53738,55957 53738 - Phosphoglucomutase, first 3 domains 55957 - Phosphoglucomutase, C-terminal domain | 0 | Direct |
48065,50729 48065 - DBL homology domain (DH-domain) 50729 - PH domain-like | 0 | Direct |
57567,57567 57567 - Serine protease inhibitors 57567 - Serine protease inhibitors | 0 | Direct |
48403,48403 48403 - Ankyrin repeat 48403 - Ankyrin repeat | 0 | Direct |
90257,90257 90257 - Myosin rod fragments 90257 - Myosin rod fragments | 0 | Direct |
53448,50370 53448 - Nucleotide-diphospho-sugar transferases 50370 - Ricin B-like lectins | 0 | Direct |
56091,50249 56091 - DNA ligase/mRNA capping enzyme, catalytic domain 50249 - Nucleic acid-binding proteins | 0 | Direct |
49854,49854 49854 - Spermadhesin, CUB domain 49854 - Spermadhesin, CUB domain | 0 | Direct |
56112,48371 56112 - Protein kinase-like (PK-like) 48371 - ARM repeat | 0 | Direct |
51126,51126 51126 - Pectin lyase-like 51126 - Pectin lyase-like | 0 | Direct |
52540,81271 52540 - P-loop containing nucleoside triphosphate hydrolases 81271 - TGS-like | 0 | Direct |
64593,74853 64593 - Intermediate filament protein, coiled coil region 74853 - Lamin A/C globular tail domain | 0 | Direct |
101912,103575 101912 - Sema domain 103575 - Plexin repeat | 0 | Direct |
52833,52833 52833 - Thioredoxin-like 52833 - Thioredoxin-like | 0 | Direct |
52113,52113 52113 - BRCT domain 52113 - BRCT domain | 0 | Direct |
52374,47323 52374 - Nucleotidylyl transferase 47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
50729,47473 50729 - PH domain-like 47473 - EF-hand | 0 | Direct |
57889,50729 57889 - Cysteine-rich domain 50729 - PH domain-like | 0 | Direct |
57903,82199 57903 - FYVE/PHD zinc finger 82199 - SET domain | 0 | Direct |
51206,51206 51206 - cAMP-binding domain-like 51206 - cAMP-binding domain-like | 0 | Direct |
55486,49854 55486 - Metalloproteases ("zincins"), catalytic domain 49854 - Spermadhesin, CUB domain | 0 | Direct |
57716,57716 57716 - Glucocorticoid receptor-like (DNA-binding domain) 57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0 | Direct |
50978,50978 50978 - WD40 repeat-like 50978 - WD40 repeat-like | 0 | Direct |
47031,50729 47031 - Second domain of FERM 50729 - PH domain-like | 0 | Direct |
47473,51695 47473 - EF-hand 51695 - PLC-like phosphodiesterases | 0 | Direct |
47741,56176 47741 - CO dehydrogenase ISP C-domain like 56176 - FAD-binding/transporter-associated domain-like | 0 | Direct |
57903,57903 57903 - FYVE/PHD zinc finger 57903 - FYVE/PHD zinc finger | 0 | Direct |
55486,57552 55486 - Metalloproteases ("zincins"), catalytic domain 57552 - Blood coagulation inhibitor (disintegrin) | 0 | Direct |
56112,56112 56112 - Protein kinase-like (PK-like) 56112 - Protein kinase-like (PK-like) | 0 | Direct |
52374,52374 52374 - Nucleotidylyl transferase 52374 - Nucleotidylyl transferase | 0 | Direct |
52743,49785 52743 - Subtilisin-like 49785 - Galactose-binding domain-like | 0 | Direct |
54211,55060 54211 - Ribosomal protein S5 domain 2-like 55060 - GHMP Kinase, C-terminal domain | 0 | Direct |
56112,55073 56112 - Protein kinase-like (PK-like) 55073 - Nucleotide cyclase | 0 | Direct |
49742,49742 49742 - PHM/PNGase F 49742 - PHM/PNGase F | 0 | Direct |
47954,47954 47954 - Cyclin-like 47954 - Cyclin-like | 0 | Direct |
52518,52922 52518 - Thiamin diphosphate-binding fold (THDP-binding) 52922 - TK C-terminal domain-like | 0 | Direct |
48371,48371 48371 - ARM repeat 48371 - ARM repeat | 0 | Direct |
47576,47576 47576 - Calponin-homology domain, CH-domain 47576 - Calponin-homology domain, CH-domain | 0 | Direct |
54928,54928 54928 - RNA-binding domain, RBD 54928 - RNA-binding domain, RBD | 0 | Direct |
57196,57196 57196 - EGF/Laminin 57196 - EGF/Laminin | 0 | Direct |
82615,82615 82615 - Polo-box domain 82615 - Polo-box domain | 0 | Direct |
55973,55973 55973 - S-adenosylmethionine synthetase 55973 - S-adenosylmethionine synthetase | 0 | Direct |
55785,55785 55785 - PYP-like sensor domain (PAS domain) 55785 - PYP-like sensor domain (PAS domain) | 0 | Direct |
48726,48726 48726 - Immunoglobulin 48726 - Immunoglobulin | 0 | Direct |
46689,46689 46689 - Homeodomain-like 46689 - Homeodomain-like | 0 | Direct |
54495,57850 54495 - UBC-like 57850 - RING/U-box | 0 | Direct |
53901,53901 53901 - Thiolase-like 53901 - Thiolase-like | 0 | Direct |
57362,57362 57362 - BPTI-like 57362 - BPTI-like | 0 | Direct |
56968,48431 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions 48431 - Lipovitellin-phosvitin complex, superhelical domain | 0 | Direct |
56059,52210 56059 - Glutathione synthetase ATP-binding domain-like 52210 - Succinyl-CoA synthetase domains | 0 | Direct |
49363,56300 49363 - Purple acid phosphatase, N-terminal domain 56300 - Metallo-dependent phosphatases | 0 | Direct |
63380,52343 63380 - Riboflavin synthase domain-like 52343 - Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | Direct |
68923,53795 68923 - PEP carboxykinase N-terminal domain 53795 - PEP carboxykinase-like | 0 | Direct |
52047,52047 52047 - RNI-like 52047 - RNI-like | 0 | Direct |
52440,56059 52440 - PreATP-grasp domain 56059 - Glutathione synthetase ATP-binding domain-like | 0 | Direct |
50677,52374 50677 - ValRS/IleRS/LeuRS editing domain 52374 - Nucleotidylyl transferase | 0 | Direct |
57196,49899 57196 - EGF/Laminin 49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
52540,46785 52540 - P-loop containing nucleoside triphosphate hydrolases 46785 - "Winged helix" DNA-binding domain | 0 | Direct |
82895,82895 82895 - TSP-1 type 1 repeat 82895 - TSP-1 type 1 repeat | 0 | Direct |
81301,81631 81301 - Nucleotidyltransferase 81631 - PAP/OAS1 substrate-binding domain | 0 | Direct |
50692,54585 50692 - ADC-like 54585 - Cdc48 domain 2-like | 0 | Direct |
54001,49758 54001 - Cysteine proteinases 49758 - Calpain large subunit, middle domain (domain III) | 0 | Direct |
52799,52799 52799 - (Phosphotyrosine protein) phosphatases II 52799 - (Phosphotyrosine protein) phosphatases II | 0 | Direct |
57535,57535 57535 - Complement control module/SCR domain 57535 - Complement control module/SCR domain | 0 | Direct |
50447,54980 50447 - Translation proteins 54980 - EF-G C-terminal domain-like | 0 | Direct |
81660,56784 81660 - Metal cation-transporting ATPase, ATP-binding domain N 56784 - HAD-like | 0 | Direct |
55550,50044 55550 - SH2 domain 50044 - SH3-domain | 0 | Direct |
57863,48403 57863 - ArfGap/RecO-like zinc finger 48403 - Ankyrin repeat | 0 | Direct |
51971,54373 51971 - Nucleotide-binding domain 54373 - FAD-linked reductases, C-terminal domain | 0 | Direct |
47769,47769 47769 - SAM/Pointed domain 47769 - SAM/Pointed domain | 0 | Direct |
49562,49562 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
81383,52047 81383 - F-box domain 52047 - RNI-like | 0 | Direct |
54211,54980 54211 - Ribosomal protein S5 domain 2-like 54980 - EF-G C-terminal domain-like | 0 | Direct |
49899,49899 49899 - Concanavalin A-like lectins/glucanases 49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
81698,81698 81698 - FF domain 81698 - FF domain | 0 | Direct |
63737,55486 63737 - Leukotriene A4 hydrolase N-terminal domain 55486 - Metalloproteases ("zincins"), catalytic domain | 0 | Direct |
117281,117281 117281 - Kelch motif 117281 - Kelch motif | 0 | Direct |
48726,49265 48726 - Immunoglobulin 49265 - Fibronectin type III | 0 | Direct |
53067,100920 53067 - Actin-like ATPase domain 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
48592,54849 48592 - GroEL equatorial domain-like 54849 - GroEL-intermediate domain like | 0 | Direct |
57184,57196 57184 - Growth factor receptor domain 57196 - EGF/Laminin | 0 | Direct |
51338,51556 51338 - Composite domain of metallo-dependent hydrolases 51556 - Metallo-dependent hydrolases | 0 | Direct |
47413,46689 47413 - lambda repressor-like DNA-binding domains 46689 - Homeodomain-like | 0 | Direct |
50044,50044 50044 - SH3-domain 50044 - SH3-domain | 0 | Direct |
57414,57414 57414 - Hairpin loop containing domain-like 57414 - Hairpin loop containing domain-like | 0 | Direct |
55729,55729 55729 - Acyl-CoA N-acyltransferases (Nat) 55729 - Acyl-CoA N-acyltransferases (Nat) | 0 | Direct |
54368,55931 54368 - Glutamine synthetase, N-terminal domain 55931 - Glutamine synthetase/guanido kinase | 0 | Direct |
55486,50923 55486 - Metalloproteases ("zincins"), catalytic domain 50923 - Hemopexin-like domain | 0 | Direct |
51445,54556 51445 - (Trans)glycosidases 54556 - Chitinase insertion domain | 0 | Direct |
51905,55424 51905 - FAD/NAD(P)-binding domain 55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | Direct |
50729,56112 50729 - PH domain-like 56112 - Protein kinase-like (PK-like) | 0 | Direct |
49493,49493 49493 - HSP40/DnaJ peptide-binding domain 49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
47895,52540 47895 - Transducin (alpha subunit), insertion domain 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
103025,101790 103025 - Folate-binding domain 101790 - Aminomethyltransferase beta-barrel domain | 0 | Direct |
51905,54373 51905 - FAD/NAD(P)-binding domain 54373 - FAD-linked reductases, C-terminal domain | 0 | Direct |
88713,88688 88713 - Glycoside hydrolase/deacetylase 88688 - Families 57/38 glycoside transferase middle domain | 0 | Direct |
56645,47203 56645 - Acyl-CoA dehydrogenase NM domain-like 47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
100950,100950 100950 - NagB/RpiA/CoA transferase-like 100950 - NagB/RpiA/CoA transferase-like | 0 | Direct |
48431,56968 48431 - Lipovitellin-phosvitin complex, superhelical domain 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | Direct |
52540,47917 52540 - P-loop containing nucleoside triphosphate hydrolases 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
54160,52540 54160 - Chromo domain-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
51695,49562 51695 - PLC-like phosphodiesterases 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
90123,52540 90123 - ABC transporter transmembrane region 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
51905,51905 51905 - FAD/NAD(P)-binding domain 51905 - FAD/NAD(P)-binding domain | 0 | Direct |
90229,90229 90229 - CCCH zinc finger 90229 - CCCH zinc finger | 0 | Direct |
57850,57845 57850 - RING/U-box 57845 - B-box zinc-binding domain | 0 | Direct |
48425,50729 48425 - Sec7 domain 50729 - PH domain-like | 0 | Direct |
49313,49313 49313 - Cadherin-like 49313 - Cadherin-like | 0 | Direct |
46785,46785 46785 - "Winged helix" DNA-binding domain 46785 - "Winged helix" DNA-binding domain | 0 | Direct |
57889,48350 57889 - Cysteine-rich domain 48350 - GTPase activation domain, GAP | 0 | Direct |
49599,54695 49599 - TRAF domain-like 54695 - POZ domain | 0 | Direct |
55326,56042 55326 - PurM N-terminal domain-like 56042 - PurM C-terminal domain-like | 0 | Direct |
49265,48726 49265 - Fibronectin type III 48726 - Immunoglobulin | 0 | Direct |
54211,55666 54211 - Ribosomal protein S5 domain 2-like 55666 - Ribonuclease PH domain 2-like | 0 | Direct |
49562,48371 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) 48371 - ARM repeat | 0 | Direct |
47203,47203 47203 - Acyl-CoA dehydrogenase C-terminal domain-like 47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
50044,55550 50044 - SH3-domain 55550 - SH2 domain | 0 | Direct |
53738,53738 53738 - Phosphoglucomutase, first 3 domains 53738 - Phosphoglucomutase, first 3 domains | 0 | Direct |
53187,49464 53187 - Zn-dependent exopeptidases 49464 - Carboxypeptidase regulatory domain-like | 0 | Direct |
51735,55347 51735 - NAD(P)-binding Rossmann-fold domains 55347 - Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | Direct |
81383,50978 81383 - F-box domain 50978 - WD40 repeat-like | 0 | Direct |
57850,57850 57850 - RING/U-box 57850 - RING/U-box | 0 | Direct |
52518,52518 52518 - Thiamin diphosphate-binding fold (THDP-binding) 52518 - Thiamin diphosphate-binding fold (THDP-binding) | 0 | Direct |
51045,51045 51045 - WW domain 51045 - WW domain | 0 | Direct |
54897,53187 54897 - Protease propeptides/inhibitors 53187 - Zn-dependent exopeptidases | 0 | Direct |
52058,52058 52058 - L domain-like 52058 - L domain-like | 0 | Direct |
57196,57184 57196 - EGF/Laminin 57184 - Growth factor receptor domain | 0 | Direct |
47587,56399 47587 - Domain of poly(ADP-ribose) polymerase 56399 - ADP-ribosylation | 0 | Direct |
54534,54534 54534 - FKBP-like 54534 - FKBP-like | 0 | Direct |
144232,82199 144232 - HIT/MYND zinc finger-like 82199 - SET domain | 0 | Direct |
50129,51735 50129 - GroES-like 51735 - NAD(P)-binding Rossmann-fold domains | 0 | Direct |
54160,54160 54160 - Chromo domain-like 54160 - Chromo domain-like | 0 | Direct |
48403,52151 48403 - Ankyrin repeat 52151 - FabD/lysophospholipase-like | 0 | Direct |
81324,53850 81324 - Voltage-gated potassium channels 53850 - Periplasmic binding protein-like II | 0 | Direct |
48464,89009 48464 - ENTH/VHS domain 89009 - GAT-like domain | 0 | Direct |
74650,51445 74650 - Galactose mutarotase-like 51445 - (Trans)glycosidases | 0 | Direct |
53187,55031 53187 - Zn-dependent exopeptidases 55031 - Bacterial exopeptidase dimerisation domain | 0 | Direct |
54637,54637 54637 - Thioesterase/thiol ester dehydrase-isomerase 54637 - Thioesterase/thiol ester dehydrase-isomerase | 0 | Direct |
47473,103506 47473 - EF-hand 103506 - Mitochondrial carrier | 0 | Direct |
54236,54236 54236 - Ubiquitin-like 54236 - Ubiquitin-like | 0 | Direct |
81333,81333 81333 - F1F0 ATP synthase subunit C 81333 - F1F0 ATP synthase subunit C | 0 | Direct |
57756,57756 57756 - Retrovirus zinc finger-like domains 57756 - Retrovirus zinc finger-like domains | 0 | Direct |
52087,101576 52087 - CRAL/TRIO domain 101576 - Supernatant protein factor (SPF), C-terminal domain | 0 | Direct |
56601,48403 56601 - beta-lactamase/transpeptidase-like 48403 - Ankyrin repeat | 0 | Direct |
54665,56003 54665 - CO dehydrogenase molybdoprotein N-domain-like 56003 - Molybdenum cofactor-binding domain | 0 | Direct |
54897,52743 54897 - Protease propeptides/inhibitors 52743 - Subtilisin-like | 0 | Direct |
54849,52029 54849 - GroEL-intermediate domain like 52029 - GroEL apical domain-like | 0 | Direct |
54980,54211 54980 - EF-G C-terminal domain-like 54211 - Ribosomal protein S5 domain 2-like | 0 | Direct |
53067,53067 53067 - Actin-like ATPase domain 53067 - Actin-like ATPase domain | 0 | Direct |
52283,51735 52283 - Formate/glycerate dehydrogenase catalytic domain-like 51735 - NAD(P)-binding Rossmann-fold domains | 0 | Direct |
49265,49265 49265 - Fibronectin type III 49265 - Fibronectin type III | 0 | Direct |
100920,100934 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
50249,55681 50249 - Nucleic acid-binding proteins 55681 - Class II aaRS and biotin synthetases | 0 | Direct |
56436,49854 56436 - C-type lectin-like 49854 - Spermadhesin, CUB domain | 0 | Direct |
48403,52113 48403 - Ankyrin repeat 52113 - BRCT domain | 0 | Direct |
161111,160240 161111 - Cation efflux protein transmembrane domain-like 160240 - Cation efflux protein cytoplasmic domain-like | 0 | Direct |
141673,50800 141673 - MOSC N-terminal domain-like 50800 - PK beta-barrel domain-like | 0 | Direct |
47220,47220 47220 - alpha-catenin/vinculin-like 47220 - alpha-catenin/vinculin-like | 0 | Direct |
81296,81296 81296 - E set domains 81296 - E set domains | 0 | Direct |
54631,54631 54631 - CBS-domain pair 54631 - CBS-domain pair | 0 | Direct |
82171,53474 82171 - DPP6 N-terminal domain-like 53474 - alpha/beta-Hydrolases | 0 | Direct |
50447,50465 50447 - Translation proteins 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
52821,52821 52821 - Rhodanese/Cell cycle control phosphatase 52821 - Rhodanese/Cell cycle control phosphatase | 0 | Direct |
57938,49493 57938 - DnaJ/Hsp40 cysteine-rich domain 49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
55681,52954 55681 - Class II aaRS and biotin synthetases 52954 - Class II aaRS ABD-related | 0 | Direct |
52540,140990 52540 - P-loop containing nucleoside triphosphate hydrolases 140990 - FtsH protease domain-like | 0 | Direct |
49348,55711 49348 - Clathrin adaptor appendage domain 55711 - Subdomain of clathrin and coatomer appendage domain | 0 | Direct |
54791,54791 54791 - Eukaryotic type KH-domain (KH-domain type I) 54791 - Eukaryotic type KH-domain (KH-domain type I) | 0 | Direct |
47923,47923 47923 - Ypt/Rab-GAP domain of gyp1p 47923 - Ypt/Rab-GAP domain of gyp1p | 0 | Direct |
52540,50447 52540 - P-loop containing nucleoside triphosphate hydrolases 50447 - Translation proteins | 0 | Direct |
54292,47741 54292 - 2Fe-2S ferredoxin-like 47741 - CO dehydrogenase ISP C-domain like | 0 | Direct |
57184,57184 57184 - Growth factor receptor domain 57184 - Growth factor receptor domain | 0 | Direct |
51556,51338 51556 - Metallo-dependent hydrolases 51338 - Composite domain of metallo-dependent hydrolases | 0 | Direct |
57889,57889 57889 - Cysteine-rich domain 57889 - Cysteine-rich domain | 0 | Direct |
50044,52540 50044 - SH3-domain 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
47090,55486 47090 - PGBD-like 55486 - Metalloproteases ("zincins"), catalytic domain | 0 | Direct |
57424,57424 57424 - LDL receptor-like module 57424 - LDL receptor-like module | 0 | Direct |
56784,81665 56784 - HAD-like 81665 - Calcium ATPase, transmembrane domain M | 0 | Direct |
57903,51197 57903 - FYVE/PHD zinc finger 51197 - Clavaminate synthase-like | 0 | Direct |
103473,100895 103473 - MFS general substrate transporter 100895 - Kazal-type serine protease inhibitors | 0 | Direct |
54585,52540 54585 - Cdc48 domain 2-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
49599,49599 49599 - TRAF domain-like 49599 - TRAF domain-like | 0 | Direct |
81811,82754 81811 - Helical domain of Sec23/24 82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
55920,46785 55920 - Creatinase/aminopeptidase 46785 - "Winged helix" DNA-binding domain | 0 | Direct |
81324,81327 81324 - Voltage-gated potassium channels 81327 - Small-conductance potassium channel | 0 | Direct |
52777,52777 52777 - CoA-dependent acyltransferases 52777 - CoA-dependent acyltransferases | 0 | Direct |
53300,53300 53300 - vWA-like 53300 - vWA-like | 0 | Direct |
48034,55931 48034 - Guanido kinase N-terminal domain 55931 - Glutamine synthetase/guanido kinase | 0 | Direct |
50978,50998 50978 - WD40 repeat-like 50998 - Quinoprotein alcohol dehydrogenase-like | 0 | Direct |
57850,117839 57850 - RING/U-box 117839 - WWE domain | 0 | Direct |
56672,100879 56672 - DNA/RNA polymerases 100879 - Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
55394,55394 55394 - Bactericidal permeability-increasing protein, BPI 55394 - Bactericidal permeability-increasing protein, BPI | 0 | Direct |
56059,51246 56059 - Glutathione synthetase ATP-binding domain-like 51246 - Rudiment single hybrid motif | 0 | Direct |
57625,57625 57625 - Invertebrate chitin-binding proteins 57625 - Invertebrate chitin-binding proteins | 0 | Direct |
53300,56436 53300 - vWA-like 56436 - C-type lectin-like | 0 | Direct |
63712,90112 63712 - Nicotinic receptor ligand binding domain-like 90112 - Neurotransmitter-gated ion-channel transmembrane pore | 0.3094 | Inherited |
57667,57667 57667 - beta-beta-alpha zinc fingers 57667 - beta-beta-alpha zinc fingers | 0.9039 | Inherited |
55550,56112 55550 - SH2 domain 56112 - Protein kinase-like (PK-like) | 1 | Inherited |
(show details)
Supra-domains annotated to this WP term (Not in SPWP)
Highlighted in gray are those with FDR>0.001
Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
56645,47203,47203 56645 - Acyl-CoA dehydrogenase NM domain-like 47203 - Acyl-CoA dehydrogenase C-terminal domain-like 47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
46938,52087,101576 46938 - CRAL/TRIO N-terminal domain 52087 - CRAL/TRIO domain 101576 - Supernatant protein factor (SPF), C-terminal domain | 0 | DIRECT |
57424,57424,57424 57424 - LDL receptor-like module 57424 - LDL receptor-like module 57424 - LDL receptor-like module | 0 | DIRECT |
54292,47741,56176 54292 - 2Fe-2S ferredoxin-like 47741 - CO dehydrogenase ISP C-domain like 56176 - FAD-binding/transporter-associated domain-like | 0 | DIRECT |
57938,49493,49493 57938 - DnaJ/Hsp40 cysteine-rich domain 49493 - HSP40/DnaJ peptide-binding domain 49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
46966,46966,46966 46966 - Spectrin repeat 46966 - Spectrin repeat 46966 - Spectrin repeat | 0 | DIRECT |
81660,56784,81665 81660 - Metal cation-transporting ATPase, ATP-binding domain N 56784 - HAD-like 81665 - Calcium ATPase, transmembrane domain M | 0 | DIRECT |
50729,47473,51695 50729 - PH domain-like 47473 - EF-hand 51695 - PLC-like phosphodiesterases | 0 | DIRECT |
90123,52540,90123 90123 - ABC transporter transmembrane region 52540 - P-loop containing nucleoside triphosphate hydrolases 90123 - ABC transporter transmembrane region | 0 | DIRECT |
54791,54791,54791 54791 - Eukaryotic type KH-domain (KH-domain type I) 54791 - Eukaryotic type KH-domain (KH-domain type I) 54791 - Eukaryotic type KH-domain (KH-domain type I) | 0 | DIRECT |
50249,50249,50249 50249 - Nucleic acid-binding proteins 50249 - Nucleic acid-binding proteins 50249 - Nucleic acid-binding proteins | 0 | DIRECT |
54928,54928,54928 54928 - RNA-binding domain, RBD 54928 - RNA-binding domain, RBD 54928 - RNA-binding domain, RBD | 0 | DIRECT |
81296,81296,81296 81296 - E set domains 81296 - E set domains 81296 - E set domains | 0 | DIRECT |
50447,54980,54211 50447 - Translation proteins 54980 - EF-G C-terminal domain-like 54211 - Ribosomal protein S5 domain 2-like | 0 | DIRECT |
56436,49854,49854 56436 - C-type lectin-like 49854 - Spermadhesin, CUB domain 49854 - Spermadhesin, CUB domain | 0 | DIRECT |
50156,50044,52540 50156 - PDZ domain-like 50044 - SH3-domain 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
48371,48371,48371 48371 - ARM repeat 48371 - ARM repeat 48371 - ARM repeat | 0 | DIRECT |
56436,56436,49854 56436 - C-type lectin-like 56436 - C-type lectin-like 49854 - Spermadhesin, CUB domain | 0 | DIRECT |
54897,52743,49785 54897 - Protease propeptides/inhibitors 52743 - Subtilisin-like 49785 - Galactose-binding domain-like | 0 | DIRECT |
57196,57196,57196 57196 - EGF/Laminin 57196 - EGF/Laminin 57196 - EGF/Laminin | 0 | DIRECT |
53738,53738,55957 53738 - Phosphoglucomutase, first 3 domains 53738 - Phosphoglucomutase, first 3 domains 55957 - Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
47090,55486,50923 47090 - PGBD-like 55486 - Metalloproteases ("zincins"), catalytic domain 50923 - Hemopexin-like domain | 0 | DIRECT |
54236,47031,50729 54236 - Ubiquitin-like 47031 - Second domain of FERM 50729 - PH domain-like | 0 | DIRECT |
49313,49313,49313 49313 - Cadherin-like 49313 - Cadherin-like 49313 - Cadherin-like | 0 | DIRECT |
55973,55973,55973 55973 - S-adenosylmethionine synthetase 55973 - S-adenosylmethionine synthetase 55973 - S-adenosylmethionine synthetase | 0 | DIRECT |
49599,49599,49599 49599 - TRAF domain-like 49599 - TRAF domain-like 49599 - TRAF domain-like | 0 | DIRECT |
50044,55550,56112 50044 - SH3-domain 55550 - SH2 domain 56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
56968,48431,56968 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions 48431 - Lipovitellin-phosvitin complex, superhelical domain 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | DIRECT |
56112,82615,82615 56112 - Protein kinase-like (PK-like) 82615 - Polo-box domain 82615 - Polo-box domain | 0 | DIRECT |
52540,50447,54980 52540 - P-loop containing nucleoside triphosphate hydrolases 50447 - Translation proteins 54980 - EF-G C-terminal domain-like | 0 | DIRECT |
54160,52540,52540 54160 - Chromo domain-like 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
53738,53738,53738 53738 - Phosphoglucomutase, first 3 domains 53738 - Phosphoglucomutase, first 3 domains 53738 - Phosphoglucomutase, first 3 domains | 0 | DIRECT |
48592,54849,52029 48592 - GroEL equatorial domain-like 54849 - GroEL-intermediate domain like 52029 - GroEL apical domain-like | 0 | DIRECT |
50692,54585,52540 50692 - ADC-like 54585 - Cdc48 domain 2-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
57362,57362,57362 57362 - BPTI-like 57362 - BPTI-like 57362 - BPTI-like | 0 | DIRECT |
82895,82895,82895 82895 - TSP-1 type 1 repeat 82895 - TSP-1 type 1 repeat 82895 - TSP-1 type 1 repeat | 0 | DIRECT |
57414,57414,57414 57414 - Hairpin loop containing domain-like 57414 - Hairpin loop containing domain-like 57414 - Hairpin loop containing domain-like | 0 | DIRECT |
52540,90123,52540 52540 - P-loop containing nucleoside triphosphate hydrolases 90123 - ABC transporter transmembrane region 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
57625,57625,57625 57625 - Invertebrate chitin-binding proteins 57625 - Invertebrate chitin-binding proteins 57625 - Invertebrate chitin-binding proteins | 0 | DIRECT |
52058,52058,52058 52058 - L domain-like 52058 - L domain-like 52058 - L domain-like | 0 | DIRECT |
52440,56059,51246 52440 - PreATP-grasp domain 56059 - Glutathione synthetase ATP-binding domain-like 51246 - Rudiment single hybrid motif | 0 | DIRECT |
48726,48726,49265 48726 - Immunoglobulin 48726 - Immunoglobulin 49265 - Fibronectin type III | 0 | DIRECT |
52540,50447,50465 52540 - P-loop containing nucleoside triphosphate hydrolases 50447 - Translation proteins 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
52833,52833,52833 52833 - Thioredoxin-like 52833 - Thioredoxin-like 52833 - Thioredoxin-like | 0 | DIRECT |
49899,49899,49899 49899 - Concanavalin A-like lectins/glucanases 49899 - Concanavalin A-like lectins/glucanases 49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
57535,57535,57535 57535 - Complement control module/SCR domain 57535 - Complement control module/SCR domain 57535 - Complement control module/SCR domain | 0 | DIRECT |
90257,90257,90257 90257 - Myosin rod fragments 90257 - Myosin rod fragments 90257 - Myosin rod fragments | 0 | DIRECT |
50044,50044,50044 50044 - SH3-domain 50044 - SH3-domain 50044 - SH3-domain | 0 | DIRECT |
57567,57567,57567 57567 - Serine protease inhibitors 57567 - Serine protease inhibitors 57567 - Serine protease inhibitors | 0 | DIRECT |
54585,52540,52540 54585 - Cdc48 domain 2-like 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
51735,48179,48179 51735 - NAD(P)-binding Rossmann-fold domains 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | DIRECT |
54980,54211,54980 54980 - EF-G C-terminal domain-like 54211 - Ribosomal protein S5 domain 2-like 54980 - EF-G C-terminal domain-like | 0 | DIRECT |
52540,52540,52540 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
74650,51445,51011 74650 - Galactose mutarotase-like 51445 - (Trans)glycosidases 51011 - Glycosyl hydrolase domain | 0 | DIRECT |
48726,48726,48726 48726 - Immunoglobulin 48726 - Immunoglobulin 48726 - Immunoglobulin | 0 | DIRECT |
48452,48452,48452 48452 - TPR-like 48452 - TPR-like 48452 - TPR-like | 0 | DIRECT |
53067,53067,100920 53067 - Actin-like ATPase domain 53067 - Actin-like ATPase domain 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
54160,54160,52540 54160 - Chromo domain-like 54160 - Chromo domain-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
48726,49265,48726 48726 - Immunoglobulin 49265 - Fibronectin type III 48726 - Immunoglobulin | 0 | DIRECT |
57850,57850,57850 57850 - RING/U-box 57850 - RING/U-box 57850 - RING/U-box | 0 | DIRECT |
57716,57716,57716 57716 - Glucocorticoid receptor-like (DNA-binding domain) 57716 - Glucocorticoid receptor-like (DNA-binding domain) 57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0 | DIRECT |
49562,48371,56112 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) 48371 - ARM repeat 56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
53067,100920,100934 53067 - Actin-like ATPase domain 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
56645,47203,47203 56645 - Acyl-CoA dehydrogenase NM domain-like 47203 - Acyl-CoA dehydrogenase C-terminal domain-like 47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
46938,52087,101576 46938 - CRAL/TRIO N-terminal domain 52087 - CRAL/TRIO domain 101576 - Supernatant protein factor (SPF), C-terminal domain | 0 | Direct |
57424,57424,57424 57424 - LDL receptor-like module 57424 - LDL receptor-like module 57424 - LDL receptor-like module | 0 | Direct |
54292,47741,56176 54292 - 2Fe-2S ferredoxin-like 47741 - CO dehydrogenase ISP C-domain like 56176 - FAD-binding/transporter-associated domain-like | 0 | Direct |
57938,49493,49493 57938 - DnaJ/Hsp40 cysteine-rich domain 49493 - HSP40/DnaJ peptide-binding domain 49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
46966,46966,46966 46966 - Spectrin repeat 46966 - Spectrin repeat 46966 - Spectrin repeat | 0 | Direct |
81660,56784,81665 81660 - Metal cation-transporting ATPase, ATP-binding domain N 56784 - HAD-like 81665 - Calcium ATPase, transmembrane domain M | 0 | Direct |
50729,47473,51695 50729 - PH domain-like 47473 - EF-hand 51695 - PLC-like phosphodiesterases | 0 | Direct |
90123,52540,90123 90123 - ABC transporter transmembrane region 52540 - P-loop containing nucleoside triphosphate hydrolases 90123 - ABC transporter transmembrane region | 0 | Direct |
54791,54791,54791 54791 - Eukaryotic type KH-domain (KH-domain type I) 54791 - Eukaryotic type KH-domain (KH-domain type I) 54791 - Eukaryotic type KH-domain (KH-domain type I) | 0 | Direct |
50249,50249,50249 50249 - Nucleic acid-binding proteins 50249 - Nucleic acid-binding proteins 50249 - Nucleic acid-binding proteins | 0 | Direct |
54928,54928,54928 54928 - RNA-binding domain, RBD 54928 - RNA-binding domain, RBD 54928 - RNA-binding domain, RBD | 0 | Direct |
81296,81296,81296 81296 - E set domains 81296 - E set domains 81296 - E set domains | 0 | Direct |
50447,54980,54211 50447 - Translation proteins 54980 - EF-G C-terminal domain-like 54211 - Ribosomal protein S5 domain 2-like | 0 | Direct |
56436,49854,49854 56436 - C-type lectin-like 49854 - Spermadhesin, CUB domain 49854 - Spermadhesin, CUB domain | 0 | Direct |
50156,50044,52540 50156 - PDZ domain-like 50044 - SH3-domain 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
48371,48371,48371 48371 - ARM repeat 48371 - ARM repeat 48371 - ARM repeat | 0 | Direct |
56436,56436,49854 56436 - C-type lectin-like 56436 - C-type lectin-like 49854 - Spermadhesin, CUB domain | 0 | Direct |
54897,52743,49785 54897 - Protease propeptides/inhibitors 52743 - Subtilisin-like 49785 - Galactose-binding domain-like | 0 | Direct |
57196,57196,57196 57196 - EGF/Laminin 57196 - EGF/Laminin 57196 - EGF/Laminin | 0 | Direct |
53738,53738,55957 53738 - Phosphoglucomutase, first 3 domains 53738 - Phosphoglucomutase, first 3 domains 55957 - Phosphoglucomutase, C-terminal domain | 0 | Direct |
47090,55486,50923 47090 - PGBD-like 55486 - Metalloproteases ("zincins"), catalytic domain 50923 - Hemopexin-like domain | 0 | Direct |
54236,47031,50729 54236 - Ubiquitin-like 47031 - Second domain of FERM 50729 - PH domain-like | 0 | Direct |
49313,49313,49313 49313 - Cadherin-like 49313 - Cadherin-like 49313 - Cadherin-like | 0 | Direct |
55973,55973,55973 55973 - S-adenosylmethionine synthetase 55973 - S-adenosylmethionine synthetase 55973 - S-adenosylmethionine synthetase | 0 | Direct |
49599,49599,49599 49599 - TRAF domain-like 49599 - TRAF domain-like 49599 - TRAF domain-like | 0 | Direct |
50044,55550,56112 50044 - SH3-domain 55550 - SH2 domain 56112 - Protein kinase-like (PK-like) | 0 | Direct |
56968,48431,56968 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions 48431 - Lipovitellin-phosvitin complex, superhelical domain 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | Direct |
56112,82615,82615 56112 - Protein kinase-like (PK-like) 82615 - Polo-box domain 82615 - Polo-box domain | 0 | Direct |
52540,50447,54980 52540 - P-loop containing nucleoside triphosphate hydrolases 50447 - Translation proteins 54980 - EF-G C-terminal domain-like | 0 | Direct |
54160,52540,52540 54160 - Chromo domain-like 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
53738,53738,53738 53738 - Phosphoglucomutase, first 3 domains 53738 - Phosphoglucomutase, first 3 domains 53738 - Phosphoglucomutase, first 3 domains | 0 | Direct |
48592,54849,52029 48592 - GroEL equatorial domain-like 54849 - GroEL-intermediate domain like 52029 - GroEL apical domain-like | 0 | Direct |
50692,54585,52540 50692 - ADC-like 54585 - Cdc48 domain 2-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
57362,57362,57362 57362 - BPTI-like 57362 - BPTI-like 57362 - BPTI-like | 0 | Direct |
82895,82895,82895 82895 - TSP-1 type 1 repeat 82895 - TSP-1 type 1 repeat 82895 - TSP-1 type 1 repeat | 0 | Direct |
57414,57414,57414 57414 - Hairpin loop containing domain-like 57414 - Hairpin loop containing domain-like 57414 - Hairpin loop containing domain-like | 0 | Direct |
52540,90123,52540 52540 - P-loop containing nucleoside triphosphate hydrolases 90123 - ABC transporter transmembrane region 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
57625,57625,57625 57625 - Invertebrate chitin-binding proteins 57625 - Invertebrate chitin-binding proteins 57625 - Invertebrate chitin-binding proteins | 0 | Direct |
52058,52058,52058 52058 - L domain-like 52058 - L domain-like 52058 - L domain-like | 0 | Direct |
52440,56059,51246 52440 - PreATP-grasp domain 56059 - Glutathione synthetase ATP-binding domain-like 51246 - Rudiment single hybrid motif | 0 | Direct |
48726,48726,49265 48726 - Immunoglobulin 48726 - Immunoglobulin 49265 - Fibronectin type III | 0 | Direct |
52540,50447,50465 52540 - P-loop containing nucleoside triphosphate hydrolases 50447 - Translation proteins 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
52833,52833,52833 52833 - Thioredoxin-like 52833 - Thioredoxin-like 52833 - Thioredoxin-like | 0 | Direct |
49899,49899,49899 49899 - Concanavalin A-like lectins/glucanases 49899 - Concanavalin A-like lectins/glucanases 49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
57535,57535,57535 57535 - Complement control module/SCR domain 57535 - Complement control module/SCR domain 57535 - Complement control module/SCR domain | 0 | Direct |
90257,90257,90257 90257 - Myosin rod fragments 90257 - Myosin rod fragments 90257 - Myosin rod fragments | 0 | Direct |
50044,50044,50044 50044 - SH3-domain 50044 - SH3-domain 50044 - SH3-domain | 0 | Direct |
57567,57567,57567 57567 - Serine protease inhibitors 57567 - Serine protease inhibitors 57567 - Serine protease inhibitors | 0 | Direct |
54585,52540,52540 54585 - Cdc48 domain 2-like 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
51735,48179,48179 51735 - NAD(P)-binding Rossmann-fold domains 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | Direct |
54980,54211,54980 54980 - EF-G C-terminal domain-like 54211 - Ribosomal protein S5 domain 2-like 54980 - EF-G C-terminal domain-like | 0 | Direct |
52540,52540,52540 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
74650,51445,51011 74650 - Galactose mutarotase-like 51445 - (Trans)glycosidases 51011 - Glycosyl hydrolase domain | 0 | Direct |
48726,48726,48726 48726 - Immunoglobulin 48726 - Immunoglobulin 48726 - Immunoglobulin | 0 | Direct |
48452,48452,48452 48452 - TPR-like 48452 - TPR-like 48452 - TPR-like | 0 | Direct |
53067,53067,100920 53067 - Actin-like ATPase domain 53067 - Actin-like ATPase domain 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
54160,54160,52540 54160 - Chromo domain-like 54160 - Chromo domain-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
48726,49265,48726 48726 - Immunoglobulin 49265 - Fibronectin type III 48726 - Immunoglobulin | 0 | Direct |
57850,57850,57850 57850 - RING/U-box 57850 - RING/U-box 57850 - RING/U-box | 0 | Direct |
57716,57716,57716 57716 - Glucocorticoid receptor-like (DNA-binding domain) 57716 - Glucocorticoid receptor-like (DNA-binding domain) 57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0 | Direct |
49562,48371,56112 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) 48371 - ARM repeat 56112 - Protein kinase-like (PK-like) | 0 | Direct |
53067,100920,100934 53067 - Actin-like ATPase domain 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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A presence/absence matrix is generated using protein domains and supradomains
for all genomes in SUPERFAMILY. The RAxML
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heuristic parsimony methods. Genome combinations, or specific clades, can be displayed as
if individual trees had been produced. However, this data is extracted from the single
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