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Worm Phenotype (WP): organism physiology variant
(show info)
Phenotype Ontology
Like Gene Ontology (GO), phenotypy ontology classifies and organizes gene-mutant/null phenotypic information from the very general at the top to more specific terms in the directed acyclic graph (DAG) by viewing an individual term as a node and its relations to parental terms (allowing for multiple parents) as directed edges. To navigate this hierarchy, we display all parental phenotypic terms to the current phenotypic term of interest ordered by their shortest distances to the current term. Also, only direct children phenotypic terms of the current phenotypic term are listed. Phenotype ontologies we have incorporated are as follows:
- Disease Ontology (DO) Ontology (DO) DO semantically integrates disease and medical vocabularies through extensive cross mapping of DO terms to MeSH, ICD, NCI thesaurus, SNOMED and OMIM.
- Human Phenotype (HP) Ontology (HP) HP captures phenotypic abnormalities that are described in OMIM, along with the corresponding disease-causing genes. It includes three complementary biological concepts: Mode_of_Inheritance (MI), ONset_and_clinical_course (ON), and Phenotypic_Abnormality (PA).
- Mouse Phenotype (MP) Ontology (MP) MP describes phenotypes of the mouse after a specific gene is genetically disrupted. Using it, Mouse Genome Informatics (MGI) provides high-coverate gene-level phenotypes for the mouse.
- Worm Phenotype (WP) Ontology (WP) WP classifies and organizes phenotype descriptions for C. elegans and other nematodes. Using it, WormBase provides primary resource for phenotype annotations for C. elegans.
- Yeast Phenotype (YP) Ontology (YP) Based on YP which is the major contributor to the Ascomycete phenotype ontology, Saccharomyces Genome Database (SGD) provides single mutant phenotypes for every gene in the yeast genome.
- Fly Phenotype (FP) Ontology (FP) FP refers to FlyBase controlled vocabulary. Specifically, a structured controlled vocabulary is used for the annotation of alleles (for their mutagen etc) in FlyBase.
- Fly Anatomy (FA) Ontology (FA) FA is a structured controlled vocabulary of the anatomy of Drosophila melanogaster, used for the description of phenotypes and where a gene is expressed.
- Zebrafish Anatomy (ZA) Ontology (ZA) ZA displays anatomical terms of the zebrafish using standard anatomical nomenclature, together with affected genes.
- Xenopus Anatomy (XA) Ontology (XA) XA represents the lineage of tissues and the timing of development for frogs (Xenopus laevis and Xenopus tropicalis). It is used to annotate Xenopus gene expression patterns and mutant and morphant phenotypes.
- Arabidopsis Plant Ontology (AP) Ontology (AP) As a major contributor to Plant Ontology which describes plant anatomical and morphological structures (AN) and growth and developmental stages (DE), the Arabidopsis Information Resource (TAIR) provides arabidopsis plant ontology annotations for the model higher plant Arabidopsis thaliana.
- Enzyme Commission (EC) Ontology (EC) Each enzyme is allocated a four-digit EC number, the first three digits of which define the reaction catalysed and the fourth of which is a unique identifier (serial number). Each enzyme is also assigned a systematic name that uniquely defines the reaction catalysed.
- DrugBank ATC (DB) Ontology (DB) In the Anatomical Therapeutic Chemical (ATC) classification system, drugs are classified in groups at five different levels according to the organ or system (1st level, anatomical main group) on which they act and their therapeutic (2nd level, therapeutic subgroup), pharmacological (3rd level, pharmacological subgroup) and chemical properties (4th level, chemical subgroup; 5th level, chemical substance). Only drugs in DrugBank are considered.
- UniProtKB KeyWords (KW) Ontology (KW) Keywords in UniProtKB are controlled vocabulary, providing a summary of the entry content and are used to index UniProtKB/Swiss-Prot entries based on 10 categories (the category "Technical term" being excluded here). Each keyword is attributed manually to UniProtKB/Swiss-Prot entries and automatically to UniProtKB/TrEMBL entries (according to specific annotation rules).
- UniProtKB UniPathway (UP) Ontology (UP) UP is a fully manually curated resource for the representation and annotation of metabolic pathways, being used as controlled vocabulary for pathway annotation in UniProtKB.
Structural Domain Phenotype Ontology and its Annotations
Structural Classification of Proteins (SCOP) classifies evolutionary-related domains into Superfamily level and Family level. Using the phenotype ontologies above, we have generated the domain-centric phenotype annotations, and further identified those phenotype terms which are the most informative to annotate SCOP domains. Promisingly, domain-centric phenotypic annotations can serve as an alternative starting point to explore genotype-phenotype relationships. We provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.
- Structural Domain Disease Ontology (DO) Ontology (SDDO) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DO.txt, and the corresponding ontology:SDDO.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Human Phenotype (HP) Ontology (SDHP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2HP.txt, and the corresponding ontology:SDHP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Mouse Phenotype (MP) Ontology (SDMP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2MP.txt, and the corresponding ontology:SDMP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Worm Phenotype (WP) Ontology (SDWP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2WP.txt, and the corresponding ontology:SDWP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Yeast Phenotype (YP) Ontology (SDYP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2YP.txt, and the corresponding ontology:SDYP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Fly Phenotype (FP) Ontology (SDFP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FP.txt, and the corresponding ontology:SDFP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Fly Anatomy (FA) Ontology (SDFA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FA.txt, and the corresponding ontology:SDFA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Zebrafish Anatomy (ZA) Ontology (SDZA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2ZA.txt, and the corresponding ontology:SDZA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Xenopus Anatomy (XA) Ontology (SDXA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2XA.txt, and the corresponding ontology:SDXA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Arabidopsis Plant Ontology (AP) Ontology (SDAP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2AP.txt, and the corresponding ontology:SDAP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Enzyme Commission (EC) Ontology (SDEC) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2EC.txt, and the corresponding ontology:SDEC.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain DrugBank ATC (DB) Ontology (SDDB) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DB.txt, and the corresponding ontology:SDDB.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain UniProtKB KeyWords (KW) Ontology (SDKW) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2KW.txt, and the corresponding ontology:SDKW.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain UniProtKB UniPathway (UP) Ontology (SDUP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2UP.txt, and the corresponding ontology:SDUP.txt) and mysql tables (Domain2PO.sql.gz).
Supra-domain Phenotype Ontology and its Annotations
Although domain-centric annotations hold great promise in describing phenotypic nature of independent domains, most domains themselves may not just work alone. In multi-domain proteins, they may be combined together to form distinct domain architectures. The recombination of the existing domains is considered as one of major driving forces for phenotypic diversificaation. As an extension, we have also generated supra-domain phenotype ontology and its annotations. Compared to domain-centric phenotype ontology and annotations (SCOP domains at the Superfamily level and Family level), this version focuses on supra-domains and individual SCOP domains ONLY at the Superfamily level. Besides, in terms of individual superfamilies, their annotations from the domain-centric version may be different from those from supra-domains version. Depending on your focus, the former should be used for the consideration of both the Superfamily level and Family level, otherwise the latter should be used if you are interested in domain combinations. Also, we provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.
- Supra-domain Domain Disease Ontology (DO) Ontology (SPDO) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DO.txt, and the corresponding ontology:SPDO.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Human Phenotype (HP) Ontology (SPHO) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2HP.txt, and the corresponding ontology:SPHO.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Mouse Phenotype (MP) Ontology (SPMP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2MP.txt, and the corresponding ontology:SPMP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Worm Phenotype (WP) Ontology (SPWP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2WP.txt, and the corresponding ontology:SPWP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Yeast Phenotype (YP) Ontology (SPYP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2YP.txt, and the corresponding ontology:SPYP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Fly Phenotype (FP) Ontology (SPFP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FP.txt, and the corresponding ontology:SPFP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Fly Anatomy (FA) Ontology (SPFA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FA.txt, and the corresponding ontology:SPFA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Zebrafish Anatomy (ZA) Ontology (SPZA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2ZA.txt, and the corresponding ontology:SPZA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Xenopus Anatomy (XA) Ontology (SPXA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2XA.txt, and the corresponding ontology:SPXA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Arabidopsis Plant Ontology (AP) Ontology (SPAP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2AP.txt, and the corresponding ontology:SPAP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Enzyme Commission (EC) Ontology (SPEC) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2EC.txt, and the corresponding ontology:SPEC.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain DrugBank ATC (DB) Ontology (SPDB) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DB.txt, and the corresponding ontology:SPDB.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain UniProtKB KeyWords (KW) Ontology (SPKW) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2KW.txt, and the corresponding ontology:SPKW.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain UniProtKB UniPathway (UP) Ontology (SPUP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2UP.txt, and the corresponding ontology:SPUP.txt) and mysql tables (SP2PO.sql.gz).
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Superfamily(show details)
Superfamily domains annotated to this WP term (Not in SDWP)
Highlighted in gray are those with FDR_all>0.001
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| Chromo domain-like | 0 | DIRECT |
| DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
| Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
| Mitochondrial carrier | 0 | DIRECT |
| Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
| ADP-ribosylation | 0 | DIRECT |
| ENTH/VHS domain | 0 | DIRECT |
| R3H domain | 0 | DIRECT |
| HSP20-like chaperones | 0 | DIRECT |
| Succinyl-CoA synthetase domains | 0 | DIRECT |
| Small-conductance potassium channel | 0 | DIRECT |
| Smc hinge domain | 0 | DIRECT |
| PEP carboxykinase-like | 0 | DIRECT |
| Aminoacid dehydrogenase-like, N-terminal domain | 0 | DIRECT |
| PUA domain-like | 0 | DIRECT |
| SWIB/MDM2 domain | 0 | DIRECT |
| Carboxypeptidase regulatory domain-like | 0 | DIRECT |
| Cullin homology domain | 0 | DIRECT |
| Invertebrate chitin-binding proteins | 0 | DIRECT |
| Restriction endonuclease-like | 0 | DIRECT |
| Integrin domains | 0 | DIRECT |
| Tubulin nucleotide-binding domain-like | 0 | DIRECT |
| alpha-catenin/vinculin-like | 0 | DIRECT |
| PABC (PABP) domain | 0 | DIRECT |
| Ferritin-like | 0 | DIRECT |
| Arginase/deacetylase | 0 | DIRECT |
| Tubby C-terminal domain-like | 0 | DIRECT |
| PurM N-terminal domain-like | 0 | DIRECT |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | DIRECT |
| ALDH-like | 0 | DIRECT |
| VPS9 domain | 0 | DIRECT |
| Ran binding protein zinc finger-like | 0 | DIRECT |
| Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | DIRECT |
| JAB1/MPN domain | 0 | DIRECT |
| Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | DIRECT |
| PHM/PNGase F | 0 | DIRECT |
| Complement control module/SCR domain | 0 | DIRECT |
| dsRNA-binding domain-like | 0 | DIRECT |
| FtsH protease domain-like | 0 | DIRECT |
| ThrRS/AlaRS common domain | 0 | DIRECT |
| eIF4e-like | 0 | DIRECT |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
| Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
| Aquaporin-like | 0 | DIRECT |
| FF domain | 0 | DIRECT |
| Subdomain of clathrin and coatomer appendage domain | 0 | DIRECT |
| Ribosomal proteins S24e, L23 and L15e | 0 | DIRECT |
| Transducin (alpha subunit), insertion domain | 0 | DIRECT |
| L-aspartase-like | 0 | DIRECT |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
| PLP-binding barrel | 0 | DIRECT |
| Nucleoporin domain | 0 | DIRECT |
| PK beta-barrel domain-like | 0 | DIRECT |
| Second domain of FERM | 0 | DIRECT |
| Terpenoid cyclases/Protein prenyltransferases | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
| Carbonic anhydrase | 0 | DIRECT |
| Hect, E3 ligase catalytic domain | 0 | DIRECT |
| TGS-like | 0 | DIRECT |
| LDH C-terminal domain-like | 0 | DIRECT |
| Heme-dependent peroxidases | 0 | DIRECT |
| RBP11-like subunits of RNA polymerase | 0 | DIRECT |
| Single hybrid motif | 0 | DIRECT |
| LysM domain | 0 | DIRECT |
| Calcium-dependent phosphotriesterase | 0 | DIRECT |
| PGBD-like | 0 | DIRECT |
| Cadherin-like | 0 | DIRECT |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | DIRECT |
| Class II aaRS ABD-related | 0 | DIRECT |
| Polo-box domain | 0 | DIRECT |
| Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | DIRECT |
| Troponin coil-coiled subunits | 0 | DIRECT |
| PreATP-grasp domain | 0 | DIRECT |
| Purine and uridine phosphorylases | 0 | DIRECT |
| Surp module (SWAP domain) | 0 | DIRECT |
| BEACH domain | 0 | DIRECT |
| WGR domain-like | 0 | DIRECT |
| Domain of poly(ADP-ribose) polymerase | 0 | DIRECT |
| L30e-like | 0 | DIRECT |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
| Fibrinogen C-terminal domain-like | 0 | DIRECT |
| Intermediate filament protein, coiled coil region | 0 | DIRECT |
| Band 7/SPFH domain | 0 | DIRECT |
| Hedgehog/intein (Hint) domain | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0 | DIRECT |
| Chitinase insertion domain | 0 | DIRECT |
| Putative DNA-binding domain | 0 | DIRECT |
| Diaminopimelate epimerase-like | 0 | DIRECT |
| 3-carboxy-cis,cis-mucoante lactonizing enzyme | 0 | DIRECT |
| GroEL equatorial domain-like | 0 | DIRECT |
| Carbohydrate phosphatase | 0 | DIRECT |
| HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
| DEATH domain | 0 | DIRECT |
| Lamin A/C globular tail domain | 0 | DIRECT |
| Aldolase | 0 | DIRECT |
| DNA ligase/mRNA capping enzyme, catalytic domain | 0 | DIRECT |
| GINS helical bundle-like | 0 | DIRECT |
| F1F0 ATP synthase subunit C | 0 | DIRECT |
| Heme-dependent catalase-like | 0 | DIRECT |
| Carbon-nitrogen hydrolase | 0 | DIRECT |
| Cullin repeat-like | 0 | DIRECT |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | DIRECT |
| Galactose oxidase, central domain | 0 | DIRECT |
| Thiamin diphosphate-binding fold (THDP-binding) | 0 | DIRECT |
| Nucleotidyltransferase | 0 | DIRECT |
| SIS domain | 0 | DIRECT |
| Rudiment single hybrid motif | 0 | DIRECT |
| Bacterial exopeptidase dimerisation domain | 0 | DIRECT |
| Citrate synthase | 0 | DIRECT |
| Protease propeptides/inhibitors | 0 | DIRECT |
| Clathrin adaptor appendage domain | 0 | DIRECT |
| Subtilisin-like | 0 | DIRECT |
| Skp1 dimerisation domain-like | 0 | DIRECT |
| AN1-like Zinc finger | 0 | DIRECT |
| GroEL-intermediate domain like | 0 | DIRECT |
| Tim10-like | 0 | DIRECT |
| Radical SAM enzymes | 0 | DIRECT |
| GroES-like | 0 | DIRECT |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
| WWE domain | 0 | DIRECT |
| HSP90 C-terminal domain | 0 | DIRECT |
| YWTD domain | 0 | DIRECT |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | DIRECT |
| MIR domain | 0 | DIRECT |
| PLC-like phosphodiesterases | 0 | DIRECT |
| Oxysterol-binding protein-like | 0 | DIRECT |
| 14-3-3 protein | 0 | DIRECT |
| Sec63 N-terminal domain-like | 0 | DIRECT |
| ARID-like | 0 | DIRECT |
| HCP-like | 0 | DIRECT |
| Translational machinery components | 0 | DIRECT |
| Isocitrate/Isopropylmalate dehydrogenase-like | 0 | DIRECT |
| CBD9-like | 0 | DIRECT |
| Pentein | 0 | DIRECT |
| SPOC domain-like | 0 | DIRECT |
| Glycolipid transfer protein, GLTP | 0 | DIRECT |
| MOSC N-terminal domain-like | 0 | DIRECT |
| Ribosomal protein L10-like | 0 | DIRECT |
| PEBP-like | 0 | DIRECT |
| Molybdenum cofactor-binding domain | 0 | DIRECT |
| SMAD/FHA domain | 0 | DIRECT |
| Periplasmic binding protein-like II | 0 | DIRECT |
| Pepsin inhibitor-3 | 0 | DIRECT |
| Elafin-like | 0 | DIRECT |
| alpha/beta knot | 0 | DIRECT |
| SCP-like | 0 | DIRECT |
| PAP/OAS1 substrate-binding domain | 0 | DIRECT |
| Clc chloride channel | 0 | DIRECT |
| Terpenoid synthases | 0 | DIRECT |
| Hypothetical protein c14orf129, hspc210 | 0 | DIRECT |
| SAICAR synthase-like | 0 | DIRECT |
| Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0 | DIRECT |
| GHMP Kinase, C-terminal domain | 0 | DIRECT |
| GAT-like domain | 0 | DIRECT |
| Formate/glycerate dehydrogenase catalytic domain-like | 0 | DIRECT |
| CO dehydrogenase molybdoprotein N-domain-like | 0 | DIRECT |
| Ribokinase-like | 0 | DIRECT |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
| YbiA-like | 0 | DIRECT |
| Helical domain of Sec23/24 | 0 | DIRECT |
| Spectrin repeat | 0 | DIRECT |
| Type II DNA topoisomerase | 0 | DIRECT |
| GroEL apical domain-like | 0 | DIRECT |
| Sec7 domain | 0 | DIRECT |
| Insulin-like | 0 | DIRECT |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | DIRECT |
| PurM C-terminal domain-like | 0 | DIRECT |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
| Sec1/munc18-like (SM) proteins | 0 | DIRECT |
| CAD & PB1 domains | 0 | DIRECT |
| 2Fe-2S ferredoxin-like | 0 | DIRECT |
| MgtE membrane domain-like | 0 | DIRECT |
| MFPT repeat-like | 0 | DIRECT |
| Nucleoside diphosphate kinase, NDK | 0 | DIRECT |
| GAS2 domain-like | 0 | DIRECT |
| Proton glutamate symport protein | 0 | DIRECT |
| FAD-dependent thiol oxidase | 0 | DIRECT |
| Zn-binding ribosomal proteins | 0 | DIRECT |
| LEM domain | 0 | DIRECT |
| beta-lactamase/transpeptidase-like | 0 | DIRECT |
| Kringle-like | 0 | DIRECT |
| lambda repressor-like DNA-binding domains | 0 | DIRECT |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
| SMAD MH1 domain | 0 | DIRECT |
| Actin-like ATPase domain | 0 | DIRECT |
| Cytochrome c | 0 | DIRECT |
| DNA repair protein MutS, domain III | 0 | DIRECT |
| CO dehydrogenase ISP C-domain like | 0 | DIRECT |
| Hormone receptor domain | 0 | DIRECT |
| Glutathione synthetase ATP-binding domain-like | 0 | DIRECT |
| Zn-finger domain of Sec23/24 | 0 | DIRECT |
| Activating enzymes of the ubiquitin-like proteins | 0 | DIRECT |
| Transducin (heterotrimeric G protein), gamma chain | 0 | DIRECT |
| CRAL/TRIO N-terminal domain | 0 | DIRECT |
| Thyroglobulin type-1 domain | 0 | DIRECT |
| Chaperone J-domain | 0 | DIRECT |
| Tricorn protease domain 2 | 0 | DIRECT |
| S-adenosylmethionine synthetase | 0 | DIRECT |
| Phosphoglucomutase, first 3 domains | 0 | DIRECT |
| Thiolase-like | 0 | DIRECT |
| Doublecortin (DC) | 0 | DIRECT |
| Phosphoenolpyruvate/pyruvate domain | 0 | DIRECT |
| Cation efflux protein cytoplasmic domain-like | 0 | DIRECT |
| PIN domain-like | 0 | DIRECT |
| cAMP-binding domain-like | 0 | DIRECT |
| Lipase/lipooxygenase domain (PLAT/LH2 domain) | 0 | DIRECT |
| Blood coagulation inhibitor (disintegrin) | 0 | DIRECT |
| PEP carboxykinase N-terminal domain | 0 | DIRECT |
| Cdc48 domain 2-like | 0 | DIRECT |
| Rap/Ran-GAP | 0 | DIRECT |
| Creatinase/prolidase N-terminal domain | 0 | DIRECT |
| ISP domain | 0 | DIRECT |
| Profilin (actin-binding protein) | 0 | DIRECT |
| PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | DIRECT |
| ArfGap/RecO-like zinc finger | 0 | DIRECT |
| Ribosomal L27 protein-like | 0 | DIRECT |
| SAND domain-like | 0 | DIRECT |
| Class I glutamine amidotransferase-like | 0 | DIRECT |
| PYP-like sensor domain (PAS domain) | 0 | DIRECT |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | DIRECT |
| Nop domain | 0 | DIRECT |
| TK C-terminal domain-like | 0 | DIRECT |
| Tubulin C-terminal domain-like | 0 | DIRECT |
| Acid phosphatase/Vanadium-dependent haloperoxidase | 0 | DIRECT |
| Ribosomal protein L1 | 0 | DIRECT |
| Cu,Zn superoxide dismutase-like | 0 | DIRECT |
| Integrin alpha N-terminal domain | 0 | DIRECT |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Ribosomal protein S10 | 0 | DIRECT |
| Alpha-L RNA-binding motif | 0 | DIRECT |
| Annexin | 0 | DIRECT |
| HMG-box | 0 | DIRECT |
| ValRS/IleRS/LeuRS editing domain | 0 | DIRECT |
| ClpP/crotonase | 0 | DIRECT |
| Cystatin/monellin | 0 | DIRECT |
| GYF domain | 0 | DIRECT |
| Outer arm dynein light chain 1 | 0 | DIRECT |
| Acyl-CoA dehydrogenase NM domain-like | 0 | DIRECT |
| P-loop containing nucleoside triphosphate hydrolases | 0.0000003705 | DIRECT |
| PH domain-like | 0.00006837 | DIRECT |
| Histone-fold | 0.000162 | DIRECT |
| Protein kinase-like (PK-like) | 0.007505 | INHERITED FROM: life span variant || alkaline pH chemotaxis variant || kinase activity reduced || aldicarb response variant || protein subcellular localization variant || protein phosphorylation reduced || transgene expression reduced || conflicting sensory integration variant || protein phosphorylation variant || colchicine resistant || egg laying response to food variant || pathogen induced gene expression variant || octanol chemotaxis defective || organism environmental stimulus response variant || positive chemotaxis variant || chemotaxis variant || metal response variant || anoxia resistant || protein expression variant || drug induced gene expression variant || chemical response variant || lipid synthesis increased || antimicrobial gene expression variant || organism osmostic stress hypersensitive |
| PDZ domain-like | 0.01455 | INHERITED FROM: aldicarb response variant || acetylcholinesterase inhibitor response variant || drug resistant |
| Nucleic acid-binding proteins | 0.0209 | INHERITED FROM: mRNA surveillance defective || hydroxyurea hypersensitive || sick || nonsense mRNA accumulation || hydroxyurea response variant || hypoxia resistant |
| Periplasmic binding protein-like I | 0.02184 | INHERITED FROM: second messenger mediated signaling variant || alkaline pH chemotaxis variant || magnesium chemotaxis defective || metabolic pathway variant || aqueous chemosensory response variant || diacetyl chemotaxis variant || aqueous positive chemotaxis variant || bromide chemotaxis variant || memory retention defective || chemosensory response variant || benzaldehyde chemotaxis variant || organism environmental stimulus response variant || AWC odorant chemotaxis defective || iodide chemotaxis defective || bromide chemotaxis defective || chemotaxis variant || carbon dioxide avoidance variant || AWC odorant chemotaxis variant || lithium chemotaxis defective || iodide chemotaxis variant || chemical response variant |
| TPR-like | 0.02306 | INHERITED FROM: positive chemotaxis defective || dauer defective || associative learning variant || light body touch resistant || chemotaxis variant || osmotic avoidance defective |
| "Winged helix" DNA-binding domain | 0.02918 | INHERITED FROM: life span variant || organism metabolism processing variant || growth rate variant || gene expression variant || germline transgene silencing variant || spontaneous mutation rate increased || chemical hypersensitive || anesthetic response variant || paraquat hypersensitive || protein aggregation induced behavior variant || protein expression increased || shortened life span || protein aggregation variant || protein protein interaction variant |
| WD40 repeat-like | 0.03405 | INHERITED FROM: osmotic avoidance variant || organism metabolism processing variant || late larval arrest || early larval arrest || protein aggregation induced behavior variant || protein aggregation variant || protein protein interaction variant |
| PapD-like | 0.03453 | INHERITED FROM: dauer lifespan variant || larval growth variant || lipid metabolism variant || dauer metabolism variant || slow growth || dauer lifespan extended || larval arrest || fat content variant || developmental growth variant |
| SH2 domain | 0.05132 | INHERITED FROM: protein expression reduced || level of protein expression variant || protein expression variant || acetylcholinesterase inhibitor resistant || aldicarb resistant |
| ARM repeat | 0.0737 | INHERITED FROM: organism hypersensitive ionizing radiation || organism metabolism processing variant || RNAi response variant || gene expression variant || sick || protein expression variant |
| Acetyl-CoA synthetase-like | 0.07501 | INHERITED FROM: lipid metabolism variant |
| Homeodomain-like | 0.08046 | INHERITED FROM: organism metabolism processing variant || growth rate variant || carbon dioxide response variant || adrenergic receptor antagonist response variant || sexually dimorphic physiology variant || inhibitor of serotonin uptake variant || carbon dioxide avoidance variant || level of transgene expression variant || imipramine resistant || ectopic expression transgene || egg laying imipramine resistant |
| Cyclin-like | 0.08292 | INHERITED FROM: protein phosphorylation reduced || protein phosphorylation variant |
| EGF/Laminin | 0.0908 | INHERITED FROM: octanol chemotaxis variant || odorant negative chemotaxis defective || octanol chemotaxis defective || negative chemotaxis variant |
| CCCH zinc finger | 0.1014 | INHERITED FROM: mRNA expression ectopic || gene expression variant || transgene expression variant || ectopic expression transgene |
| Translation proteins | 0.1121 | INHERITED FROM: organism metabolism processing variant || protein phosphorylation increased || gene expression variant || protein phosphorylation variant || transgene expression variant || mRNA levels increased || sick || protein aggregation variant || protein protein interaction variant |
| Ankyrin repeat | 0.118 | INHERITED FROM: octanol chemotaxis variant || odorant negative chemotaxis defective || chemosensory response variant || octanol chemotaxis defective || organism heat response variant || chemotaxis variant |
| Galactose-binding domain-like | 0.128 | INHERITED FROM: protein interaction variant || protein aggregation variant || protein protein interaction variant |
| Nucleotide cyclase | 0.1386 | INHERITED FROM: osmotic avoidance variant || second messenger mediated signaling variant || alkaline pH chemotaxis variant || magnesium chemotaxis defective || metabolic pathway variant || diacetyl chemotaxis variant || carbon dioxide response variant || bromide chemotaxis variant || chemosensory response variant || anion positive chemotaxis defective || organism environmental stimulus response variant || AWC odorant chemotaxis defective || positive chemotaxis variant || iodide chemotaxis defective || bromide chemotaxis defective || cation positive chemotaxis defective || chemotaxis variant || AWC odorant chemotaxis variant || lithium chemotaxis defective || iodide chemotaxis variant || cation positive chemotaxis variant |
| ABC transporter transmembrane region | 0.1386 | INHERITED FROM: cadmium response variant || RNAi response variant || organism environmental stimulus response variant || metal response variant || colchicine hypersensitive |
| HLH, helix-loop-helix DNA-binding domain | 0.1386 | INHERITED FROM: organism metabolism processing variant || gene expression level reduced || hypoxia response variant || lysine chemotaxis defective || RNA expression variant || ectopic expression transgene || aqueous positive chemotaxis defective |
| Calcium ATPase, transmembrane domain M | 0.1507 | INHERITED FROM: organism environmental stimulus response variant || nicotine hypersensitive || lipid composition variant |
| RNI-like | 0.1553 | INHERITED FROM: resistant to protein aggregation induced paralysis |
| Regulator of G-protein signaling, RGS | 0.1663 | INHERITED FROM: mechanosensation variant || negative chemotaxis variant || chemotaxis variant |
| Metal cation-transporting ATPase, ATP-binding domain N | 0.1663 | INHERITED FROM: organism environmental stimulus response variant || nicotine hypersensitive || lipid composition variant |
| Calcium ATPase, transduction domain A | 0.1834 | INHERITED FROM: organism environmental stimulus response variant || nicotine hypersensitive |
| Class II aaRS and biotin synthetases | 0.1834 | INHERITED FROM: organism metabolism processing variant || gene expression variant || transgene expression variant || hypoxia response variant || organism environmental stimulus response variant || oxygen response variant || hypoxia resistant |
| SH3-domain | 0.1951 | INHERITED FROM: aldicarb response variant || protein phosphorylation variant || protein expression reduced || protein expression variant |
| Quinoprotein alcohol dehydrogenase-like | 0.2024 | INHERITED FROM: mid larval arrest || mRNA levels increased || hypoxia response variant || fat content increased || L2 arrest |
| Multidrug efflux transporter AcrB transmembrane domain | 0.2216 | INHERITED FROM: odorant positive chemotaxis defective || positive chemotaxis defective || embryo osmotic integrity defective early emb || odorant chemosensory response variant || egg integrity defective early emb || chemotaxis variant |
| DBL homology domain (DH-domain) | 0.2232 | INHERITED FROM: aldicarb response variant || organism pathogen response variant || organism environmental stimulus response variant || bacterially unswollen || pathogen resistance increased |
| E set domains | 0.2469 | INHERITED FROM: paraquat hypersensitive |
| Cytochrome P450 | 0.259 | INHERITED FROM: cadmium response variant || metal response variant |
| Multidrug resistance efflux transporter EmrE | 0.2704 | INHERITED FROM: organism pathogen response variant || bacterially unswollen || pathogen resistance increased |
| BRCT domain | 0.2769 | INHERITED FROM: organism ionizing radiation response variant |
| Bromodomain | 0.2967 | INHERITED FROM: drug adaptation variant || acute functional tolerance to alcohol defective || anesthetic resistant || anesthetic response variant || organism UV hypersensitive || sick || organism UV response variant || ethanol resistant |
| 6-phosphogluconate dehydrogenase C-terminal domain-like | 0.2967 | INHERITED FROM: lipid metabolism variant || fat content variant |
| Nucleotidylyl transferase | 0.3189 | INHERITED FROM: organism metabolism processing variant || mRNA surveillance defective || transgene expression increased || hypoxia response variant || organism environmental stimulus response variant || paraquat resistant || oxygen response variant || hypoxia resistant |
| Cysteine proteinases | 0.3196 | INHERITED FROM: hypoosmotic shock hypersensitive || osmotic integrity variant || organism metabolism processing variant || protein interaction variant || pattern of transgene expression variant || paraquat hypersensitive || protein protein interaction variant |
| SNARE-like | 0.3263 | INHERITED FROM: organism metabolism processing variant || gene expression variant || transgene subcellular localization variant || transgene expression variant || pattern of transgene expression variant || sick || acetylcholinesterase inhibitor resistant || aldicarb resistant |
| POZ domain | 0.3279 | INHERITED FROM: early larval arrest || resistant to protein aggregation induced paralysis || chemical hypersensitive || protein aggregation induced behavior variant || L1 arrest |
| Ribosomal protein S5 domain 2-like | 0.3356 | INHERITED FROM: transgene expression variant || early larval arrest |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0.3414 | INHERITED FROM: RNAi response variant || growth rate variant || protein subcellular localization variant || organism pathogen response variant || innate immune response variant || nose touch variant || organism environmental stimulus response variant || aging variant || protein expression variant || drug induced gene expression variant || chemical response variant || antimicrobial gene expression variant || drug resistant |
| SAM/Pointed domain | 0.3415 | INHERITED FROM: aldicarb response variant |
| Lipocalins | 0.3417 | INHERITED FROM: life span variant || lipid metabolism variant || paraquat hypersensitive || fat content variant || fat content increased |
| UDP-Glycosyltransferase/glycogen phosphorylase | 0.3518 | INHERITED FROM: organism osmotic stress response variant |
| Nicotinic receptor ligand binding domain-like | 0.3914 | INHERITED FROM: hypoosmotic shock hypersensitive || sodium chloride chemotaxis variant || mechanosensation variant || aqueous chemosensory response variant || selenium response variant || nicotine resistant || organism environmental stimulus response variant || drug response variant || antihelmintic response variant || DMPP response variant || cholinergic agonist resistant || chemical response variant |
| Translation proteins SH3-like domain | 0.3929 | INHERITED FROM: organism metabolism processing variant || gene expression variant || transgene expression variant || early larval arrest || protein aggregation variant |
| Cation efflux protein transmembrane domain-like | 0.3929 | INHERITED FROM: cadmium response variant || cadmium hypersensitive || metal response variant |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.415 | INHERITED FROM: hypoosmotic shock hypersensitive || sodium chloride chemotaxis variant || mechanosensation variant || aqueous chemosensory response variant || selenium response variant || nicotine resistant || organism environmental stimulus response variant || drug response variant || positive chemotaxis variant || antihelmintic response variant || DMPP response variant || cholinergic agonist resistant || chemical response variant |
| Acid proteases | 0.419 | INHERITED FROM: hypoosmotic shock hypersensitive || osmotic integrity variant || organism metabolism processing variant || gene expression variant || transgene subcellular localization variant || transgene expression variant || protein interaction variant || pattern of transgene expression variant || protein aggregation variant || protein protein interaction variant |
| Cysteine-rich domain | 0.4435 | INHERITED FROM: odorant positive chemotaxis variant || organism metabolism processing variant || aldicarb response variant || protein subcellular localization variant || organism pathogen response variant || innate immune response variant || organism oxidative stress resistant || odorant chemosensory response variant || bacterially unswollen || positive chemotaxis variant || drug induced gene expression variant || antimicrobial gene expression variant |
| FYVE/PHD zinc finger | 0.446 | INHERITED FROM: protein methylation variant || organism UV hypersensitive || organism UV response variant || protein modification variant || ectopic expression transgene |
| Ubiquitin-like | 0.4719 | INHERITED FROM: organism metabolism processing variant || protein interaction variant || protein aggregation variant || protein protein interaction variant |
| RNA-binding domain, RBD | 0.4786 | INHERITED FROM: starvation induced apoptosis variant || organism metabolism processing variant || maintenance of gene silencing variant || RNA processing variant || sick || RNA expression variant || mRNA export variant |
| HAD-like | 0.5055 | INHERITED FROM: transgene subcellular localization variant || nicotine hypersensitive || lipid composition variant |
| PRTase-like | 0.5166 | INHERITED FROM: Fluorouracil resistant || drug resistant |
| DHS-like NAD/FAD-binding domain | 0.5166 | INHERITED FROM: life span variant || protein acetylation variant || protein modification variant |
| Myosin rod fragments | 0.5166 | INHERITED FROM: drug resistant |
| t-snare proteins | 0.5166 | INHERITED FROM: drug hypersensitive |
| Voltage-gated potassium channels | 0.5505 | INHERITED FROM: mechanosensation variant || growth rate variant || positive chemotaxis defective || adrenergic receptor antagonist response variant || serotonin response variant |
| Ferredoxin reductase-like, C-terminal NADP-linked domain | 0.5638 | INHERITED FROM: pattern protein expression variant |
| Riboflavin synthase domain-like | 0.5638 | INHERITED FROM: pattern protein expression variant |
| Cystine-knot cytokines | 0.572 | INHERITED FROM: nicotine response variant || levamisole response variant |
| WW domain | 0.572 | INHERITED FROM: maintenance of gene silencing variant || aldicarb resistant |
| Sm-like ribonucleoproteins | 0.572 | INHERITED FROM: protein subcellular localization variant || gene expression variant || transgene expression variant || pattern of transgene expression variant || sick || organism heat response variant || shortened life span |
| FAD-linked reductases, C-terminal domain | 0.572 | INHERITED FROM: life span variant |
| FAD/NAD(P)-binding domain | 0.6087 | INHERITED FROM: life span variant || pesticide response variant |
| Seven-hairpin glycosidases | 0.615 | INHERITED FROM: extended life span || protein aggregation variant || protein protein interaction variant |
| SET domain | 0.6155 | INHERITED FROM: life span variant || RNAi response variant || dosage compensation variant || protein methylation variant || spontaneous mutation rate increased || maintenance of gene silencing variant || histone methylation variant || protein expression variant || protein modification variant || shortened life span || ectopic expression antibody || somatic transgene silencing variant |
| UBC-like | 0.6387 | INHERITED FROM: organism metabolism processing variant || late larval arrest || gene expression variant || transgene subcellular localization variant || protein interaction variant || pattern of transgene expression variant || sick || protein aggregation variant || protein protein interaction variant |
| MFS general substrate transporter | 0.6496 | INHERITED FROM: organism high sodium chloride hypersensitive |
| Clavaminate synthase-like | 0.6536 | INHERITED FROM: life span variant || organism temperature response variant |
| Nucleotide-binding domain | 0.6706 | INHERITED FROM: life span variant || extended life span |
| Lipovitellin-phosvitin complex, superhelical domain | 0.6706 | INHERITED FROM: life span variant || organism pathogen response variant || pathogen susceptibility increased || organism environmental stimulus response variant |
| KA1-like | 0.6706 | INHERITED FROM: RNA expression variant |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0.6706 | INHERITED FROM: life span variant || organism pathogen response variant || pathogen susceptibility increased || organism environmental stimulus response variant |
| Osmotin, thaumatin-like protein | 0.6706 | INHERITED FROM: cadmium response variant || cadmium hypersensitive || metal response variant |
| Rhodanese/Cell cycle control phosphatase | 0.6764 | INHERITED FROM: pathogen susceptibility increased |
| S15/NS1 RNA-binding domain | 0.732 | INHERITED FROM: transgene expression increased |
| Glucocorticoid receptor-like (DNA-binding domain) | 0.769 | INHERITED FROM: transgene expression reduced || dauer resistance to harsh conditions variant || gene expression level reduced || gene expression level high || level of transgene expression variant || SDS sensitive dauer || fat content increased |
| GST C-terminal domain-like | 0.772 | INHERITED FROM: enzyme activity reduced || cadmium response variant || organism stress response variant || organism heat hypersensitive || cadmium hypersensitive || organism environmental stimulus response variant || organism electrophilic stress hypersensitive || enzyme activity variant |
| Ribonuclease H-like | 0.7826 | INHERITED FROM: RNAi enhanced || RNAi response variant || siRNA expression variant || maintenance of gene silencing variant || RNA expression variant || somatic transgene silencing variant || 21U RNA expression variant |
| alpha/beta-Hydrolases | 0.7829 | INHERITED FROM: acetylcholinesterase reduced || acetylcholinesterase activity variant |
| PAZ domain | 0.7862 | INHERITED FROM: RNAi enhanced || RNAi response variant || siRNA expression variant || mRNA levels increased || maintenance of gene silencing variant || RNA expression variant || somatic transgene silencing variant || 21U RNA expression variant |
| ADC-like | 0.7982 | INHERITED FROM: protein interaction variant || level of transgene expression variant || protein aggregation variant || protein protein interaction variant |
| MIT domain | 0.7982 | INHERITED FROM: protein interaction variant || protein aggregation variant || protein protein interaction variant |
| Fibronectin type III | 0.848 | INHERITED FROM: growth rate variant |
| UBA-like | 0.9001 | INHERITED FROM: protein aggregation variant || protein protein interaction variant |
| Leucine zipper domain | 0.9025 | INHERITED FROM: transgene expression reduced || organism pathogen response variant || pore forming toxin response variant || mRNA levels reduced || organism environmental stimulus response variant || mRNA expression variant || level of transgene expression variant |
| GTPase activation domain, GAP | 0.9142 | INHERITED FROM: protein expression variant |
| EF-hand | 0.9198 | INHERITED FROM: protein interaction variant || protein aggregation variant |
| p53-like transcription factors | 0.9665 | INHERITED FROM: gene expression level reduced || level of transgene expression variant || ectopic expression transgene |
| Ribonuclease PH domain 2-like | 0.9724 | INHERITED FROM: early larval arrest |
| Immunoglobulin | 0.9976 | INHERITED FROM: growth rate variant || aldicarb response variant |
| Family A G protein-coupled receptor-like | 1 | INHERITED FROM: locomotion rate serotonin variant || serotonin induced fat reduction variant || male tail curling serotonin variant || serotonin induced pumping variant |
| Ligand-binding domain in the NO signalling and Golgi transport | 1 | INHERITED FROM: carbon dioxide response variant || carbon dioxide avoidance variant |
| Saposin | 1 | INHERITED FROM: pathogen load variant || transgene expression reduced || organism pathogen response variant || transgene expression variant || increased pathogen survival || level of transgene expression variant |
| Cyclophilin-like | 1 | INHERITED FROM: gene expression variant || transgene subcellular localization variant || transgene expression variant || protein interaction variant || pattern of transgene expression variant || protein aggregation variant || protein protein interaction variant |
| beta-beta-alpha zinc fingers | 1 | INHERITED FROM: organism metabolism processing variant || inhibitor of serotonin uptake variant || egg laying serotonin resistant || imipramine resistant || egg laying imipramine resistant |
| Nuclear receptor ligand-binding domain | 1 | INHERITED FROM: lipid metabolism variant || transgene expression reduced || dauer resistance to harsh conditions variant || gene expression level reduced || gene expression level high || level of transgene expression variant || SDS sensitive dauer || fat content increased |
| F-box domain | 1 | INHERITED FROM: resistant to protein aggregation induced paralysis |
| Bet v1-like | 1 | INHERITED FROM: growth rate variant |
| FKBP-like | 1 | INHERITED FROM: transgene subcellular localization variant || protein interaction variant || pattern of transgene expression variant || protein aggregation variant || protein protein interaction variant |
| B-box zinc-binding domain | 1 | INHERITED FROM: organism metabolism processing variant || gene expression variant || transgene subcellular localization variant || transgene expression variant || protein interaction variant || protein aggregation variant || protein protein interaction variant |
| Eukaryotic type KH-domain (KH-domain type I) | 1 | INHERITED FROM: RNA expression variant |
| Thioredoxin-like | 1 | INHERITED FROM: enzyme activity reduced || organism stress response variant || organism heat hypersensitive || cadmium hypersensitive || pesticide response variant || organism environmental stimulus response variant || organism electrophilic stress hypersensitive || paraquat response variant || enzyme activity variant |
| RING/U-box | 1 | INHERITED FROM: organism metabolism processing variant || gene expression variant || transgene subcellular localization variant || transgene expression variant || protein interaction variant || pattern of transgene expression variant || protein aggregation variant || protein protein interaction variant |
| CoA-dependent acyltransferases | 1 | INHERITED FROM: fat content variant |
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| Chromo domain-like | 0 | Direct |
| DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
| Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
| Mitochondrial carrier | 0 | Direct |
| Composite domain of metallo-dependent hydrolases | 0 | Direct |
| ADP-ribosylation | 0 | Direct |
| ENTH/VHS domain | 0 | Direct |
| R3H domain | 0 | Direct |
| HSP20-like chaperones | 0 | Direct |
| Succinyl-CoA synthetase domains | 0 | Direct |
| Small-conductance potassium channel | 0 | Direct |
| Smc hinge domain | 0 | Direct |
| PEP carboxykinase-like | 0 | Direct |
| Aminoacid dehydrogenase-like, N-terminal domain | 0 | Direct |
| PUA domain-like | 0 | Direct |
| SWIB/MDM2 domain | 0 | Direct |
| Carboxypeptidase regulatory domain-like | 0 | Direct |
| Cullin homology domain | 0 | Direct |
| Invertebrate chitin-binding proteins | 0 | Direct |
| Restriction endonuclease-like | 0 | Direct |
| Integrin domains | 0 | Direct |
| Tubulin nucleotide-binding domain-like | 0 | Direct |
| alpha-catenin/vinculin-like | 0 | Direct |
| PABC (PABP) domain | 0 | Direct |
| Ferritin-like | 0 | Direct |
| Arginase/deacetylase | 0 | Direct |
| Tubby C-terminal domain-like | 0 | Direct |
| PurM N-terminal domain-like | 0 | Direct |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | Direct |
| ALDH-like | 0 | Direct |
| VPS9 domain | 0 | Direct |
| Ran binding protein zinc finger-like | 0 | Direct |
| Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | Direct |
| JAB1/MPN domain | 0 | Direct |
| Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | Direct |
| PHM/PNGase F | 0 | Direct |
| Complement control module/SCR domain | 0 | Direct |
| dsRNA-binding domain-like | 0 | Direct |
| FtsH protease domain-like | 0 | Direct |
| ThrRS/AlaRS common domain | 0 | Direct |
| eIF4e-like | 0 | Direct |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | Direct |
| Phosphoglucomutase, C-terminal domain | 0 | Direct |
| Aquaporin-like | 0 | Direct |
| FF domain | 0 | Direct |
| Subdomain of clathrin and coatomer appendage domain | 0 | Direct |
| Ribosomal proteins S24e, L23 and L15e | 0 | Direct |
| Transducin (alpha subunit), insertion domain | 0 | Direct |
| L-aspartase-like | 0 | Direct |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
| PLP-binding barrel | 0 | Direct |
| Nucleoporin domain | 0 | Direct |
| PK beta-barrel domain-like | 0 | Direct |
| Second domain of FERM | 0 | Direct |
| Terpenoid cyclases/Protein prenyltransferases | 0 | Direct |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
| Carbonic anhydrase | 0 | Direct |
| Hect, E3 ligase catalytic domain | 0 | Direct |
| TGS-like | 0 | Direct |
| LDH C-terminal domain-like | 0 | Direct |
| Heme-dependent peroxidases | 0 | Direct |
| RBP11-like subunits of RNA polymerase | 0 | Direct |
| Single hybrid motif | 0 | Direct |
| LysM domain | 0 | Direct |
| Calcium-dependent phosphotriesterase | 0 | Direct |
| PGBD-like | 0 | Direct |
| Cadherin-like | 0 | Direct |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | Direct |
| Class II aaRS ABD-related | 0 | Direct |
| Polo-box domain | 0 | Direct |
| Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | Direct |
| Troponin coil-coiled subunits | 0 | Direct |
| PreATP-grasp domain | 0 | Direct |
| Purine and uridine phosphorylases | 0 | Direct |
| Surp module (SWAP domain) | 0 | Direct |
| BEACH domain | 0 | Direct |
| WGR domain-like | 0 | Direct |
| Domain of poly(ADP-ribose) polymerase | 0 | Direct |
| L30e-like | 0 | Direct |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
| Fibrinogen C-terminal domain-like | 0 | Direct |
| Intermediate filament protein, coiled coil region | 0 | Direct |
| Band 7/SPFH domain | 0 | Direct |
| Hedgehog/intein (Hint) domain | 0 | Direct |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0 | Direct |
| Chitinase insertion domain | 0 | Direct |
| Putative DNA-binding domain | 0 | Direct |
| Diaminopimelate epimerase-like | 0 | Direct |
| 3-carboxy-cis,cis-mucoante lactonizing enzyme | 0 | Direct |
| GroEL equatorial domain-like | 0 | Direct |
| Carbohydrate phosphatase | 0 | Direct |
| HSP40/DnaJ peptide-binding domain | 0 | Direct |
| DEATH domain | 0 | Direct |
| Lamin A/C globular tail domain | 0 | Direct |
| Aldolase | 0 | Direct |
| DNA ligase/mRNA capping enzyme, catalytic domain | 0 | Direct |
| GINS helical bundle-like | 0 | Direct |
| F1F0 ATP synthase subunit C | 0 | Direct |
| Heme-dependent catalase-like | 0 | Direct |
| Carbon-nitrogen hydrolase | 0 | Direct |
| Cullin repeat-like | 0 | Direct |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | Direct |
| Galactose oxidase, central domain | 0 | Direct |
| Thiamin diphosphate-binding fold (THDP-binding) | 0 | Direct |
| Nucleotidyltransferase | 0 | Direct |
| SIS domain | 0 | Direct |
| Rudiment single hybrid motif | 0 | Direct |
| Bacterial exopeptidase dimerisation domain | 0 | Direct |
| Citrate synthase | 0 | Direct |
| Protease propeptides/inhibitors | 0 | Direct |
| Clathrin adaptor appendage domain | 0 | Direct |
| Subtilisin-like | 0 | Direct |
| Skp1 dimerisation domain-like | 0 | Direct |
| AN1-like Zinc finger | 0 | Direct |
| GroEL-intermediate domain like | 0 | Direct |
| Tim10-like | 0 | Direct |
| Radical SAM enzymes | 0 | Direct |
| GroES-like | 0 | Direct |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
| WWE domain | 0 | Direct |
| HSP90 C-terminal domain | 0 | Direct |
| YWTD domain | 0 | Direct |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | Direct |
| MIR domain | 0 | Direct |
| PLC-like phosphodiesterases | 0 | Direct |
| Oxysterol-binding protein-like | 0 | Direct |
| 14-3-3 protein | 0 | Direct |
| Sec63 N-terminal domain-like | 0 | Direct |
| ARID-like | 0 | Direct |
| HCP-like | 0 | Direct |
| Translational machinery components | 0 | Direct |
| Isocitrate/Isopropylmalate dehydrogenase-like | 0 | Direct |
| CBD9-like | 0 | Direct |
| Pentein | 0 | Direct |
| SPOC domain-like | 0 | Direct |
| Glycolipid transfer protein, GLTP | 0 | Direct |
| MOSC N-terminal domain-like | 0 | Direct |
| Ribosomal protein L10-like | 0 | Direct |
| PEBP-like | 0 | Direct |
| Molybdenum cofactor-binding domain | 0 | Direct |
| SMAD/FHA domain | 0 | Direct |
| Periplasmic binding protein-like II | 0 | Direct |
| Pepsin inhibitor-3 | 0 | Direct |
| Elafin-like | 0 | Direct |
| alpha/beta knot | 0 | Direct |
| SCP-like | 0 | Direct |
| PAP/OAS1 substrate-binding domain | 0 | Direct |
| Clc chloride channel | 0 | Direct |
| Terpenoid synthases | 0 | Direct |
| Hypothetical protein c14orf129, hspc210 | 0 | Direct |
| SAICAR synthase-like | 0 | Direct |
| Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0 | Direct |
| GHMP Kinase, C-terminal domain | 0 | Direct |
| GAT-like domain | 0 | Direct |
| Formate/glycerate dehydrogenase catalytic domain-like | 0 | Direct |
| CO dehydrogenase molybdoprotein N-domain-like | 0 | Direct |
| Ribokinase-like | 0 | Direct |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
| YbiA-like | 0 | Direct |
| Helical domain of Sec23/24 | 0 | Direct |
| Spectrin repeat | 0 | Direct |
| Type II DNA topoisomerase | 0 | Direct |
| GroEL apical domain-like | 0 | Direct |
| Sec7 domain | 0 | Direct |
| Insulin-like | 0 | Direct |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | Direct |
| PurM C-terminal domain-like | 0 | Direct |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
| Sec1/munc18-like (SM) proteins | 0 | Direct |
| CAD & PB1 domains | 0 | Direct |
| 2Fe-2S ferredoxin-like | 0 | Direct |
| MgtE membrane domain-like | 0 | Direct |
| MFPT repeat-like | 0 | Direct |
| Nucleoside diphosphate kinase, NDK | 0 | Direct |
| GAS2 domain-like | 0 | Direct |
| Proton glutamate symport protein | 0 | Direct |
| FAD-dependent thiol oxidase | 0 | Direct |
| Zn-binding ribosomal proteins | 0 | Direct |
| LEM domain | 0 | Direct |
| beta-lactamase/transpeptidase-like | 0 | Direct |
| Kringle-like | 0 | Direct |
| lambda repressor-like DNA-binding domains | 0 | Direct |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
| SMAD MH1 domain | 0 | Direct |
| Actin-like ATPase domain | 0 | Direct |
| Cytochrome c | 0 | Direct |
| DNA repair protein MutS, domain III | 0 | Direct |
| CO dehydrogenase ISP C-domain like | 0 | Direct |
| Hormone receptor domain | 0 | Direct |
| Glutathione synthetase ATP-binding domain-like | 0 | Direct |
| Zn-finger domain of Sec23/24 | 0 | Direct |
| Activating enzymes of the ubiquitin-like proteins | 0 | Direct |
| Transducin (heterotrimeric G protein), gamma chain | 0 | Direct |
| CRAL/TRIO N-terminal domain | 0 | Direct |
| Thyroglobulin type-1 domain | 0 | Direct |
| Chaperone J-domain | 0 | Direct |
| Tricorn protease domain 2 | 0 | Direct |
| S-adenosylmethionine synthetase | 0 | Direct |
| Phosphoglucomutase, first 3 domains | 0 | Direct |
| Thiolase-like | 0 | Direct |
| Doublecortin (DC) | 0 | Direct |
| Phosphoenolpyruvate/pyruvate domain | 0 | Direct |
| Cation efflux protein cytoplasmic domain-like | 0 | Direct |
| PIN domain-like | 0 | Direct |
| cAMP-binding domain-like | 0 | Direct |
| Lipase/lipooxygenase domain (PLAT/LH2 domain) | 0 | Direct |
| Blood coagulation inhibitor (disintegrin) | 0 | Direct |
| PEP carboxykinase N-terminal domain | 0 | Direct |
| Cdc48 domain 2-like | 0 | Direct |
| Rap/Ran-GAP | 0 | Direct |
| Creatinase/prolidase N-terminal domain | 0 | Direct |
| ISP domain | 0 | Direct |
| Profilin (actin-binding protein) | 0 | Direct |
| PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | Direct |
| ArfGap/RecO-like zinc finger | 0 | Direct |
| Ribosomal L27 protein-like | 0 | Direct |
| SAND domain-like | 0 | Direct |
| Class I glutamine amidotransferase-like | 0 | Direct |
| PYP-like sensor domain (PAS domain) | 0 | Direct |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | Direct |
| Nop domain | 0 | Direct |
| TK C-terminal domain-like | 0 | Direct |
| Tubulin C-terminal domain-like | 0 | Direct |
| Acid phosphatase/Vanadium-dependent haloperoxidase | 0 | Direct |
| Ribosomal protein L1 | 0 | Direct |
| Cu,Zn superoxide dismutase-like | 0 | Direct |
| Integrin alpha N-terminal domain | 0 | Direct |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Ribosomal protein S10 | 0 | Direct |
| Alpha-L RNA-binding motif | 0 | Direct |
| Annexin | 0 | Direct |
| HMG-box | 0 | Direct |
| ValRS/IleRS/LeuRS editing domain | 0 | Direct |
| ClpP/crotonase | 0 | Direct |
| Cystatin/monellin | 0 | Direct |
| GYF domain | 0 | Direct |
| Outer arm dynein light chain 1 | 0 | Direct |
| Acyl-CoA dehydrogenase NM domain-like | 0 | Direct |
| P-loop containing nucleoside triphosphate hydrolases | 0.0000003705 | Direct |
| PH domain-like | 0.00006837 | Direct |
| Histone-fold | 0.000162 | Direct |
| Protein kinase-like (PK-like) | 0.007505 | Inherited |
| PDZ domain-like | 0.01455 | Inherited |
| Nucleic acid-binding proteins | 0.0209 | Inherited |
| Periplasmic binding protein-like I | 0.02184 | Inherited |
| TPR-like | 0.02306 | Inherited |
| "Winged helix" DNA-binding domain | 0.02918 | Inherited |
| WD40 repeat-like | 0.03405 | Inherited |
| PapD-like | 0.03453 | Inherited |
| SH2 domain | 0.05132 | Inherited |
| ARM repeat | 0.0737 | Inherited |
| Acetyl-CoA synthetase-like | 0.07501 | Inherited |
| Homeodomain-like | 0.08046 | Inherited |
| Cyclin-like | 0.08292 | Inherited |
| EGF/Laminin | 0.0908 | Inherited |
| CCCH zinc finger | 0.1014 | Inherited |
| Translation proteins | 0.1121 | Inherited |
| Ankyrin repeat | 0.118 | Inherited |
| Galactose-binding domain-like | 0.128 | Inherited |
| Nucleotide cyclase | 0.1386 | Inherited |
| ABC transporter transmembrane region | 0.1386 | Inherited |
| HLH, helix-loop-helix DNA-binding domain | 0.1386 | Inherited |
| Calcium ATPase, transmembrane domain M | 0.1507 | Inherited |
| RNI-like | 0.1553 | Inherited |
| Regulator of G-protein signaling, RGS | 0.1663 | Inherited |
| Metal cation-transporting ATPase, ATP-binding domain N | 0.1663 | Inherited |
| Calcium ATPase, transduction domain A | 0.1834 | Inherited |
| Class II aaRS and biotin synthetases | 0.1834 | Inherited |
| SH3-domain | 0.1951 | Inherited |
| Quinoprotein alcohol dehydrogenase-like | 0.2024 | Inherited |
| Multidrug efflux transporter AcrB transmembrane domain | 0.2216 | Inherited |
| DBL homology domain (DH-domain) | 0.2232 | Inherited |
| E set domains | 0.2469 | Inherited |
| Cytochrome P450 | 0.259 | Inherited |
| Multidrug resistance efflux transporter EmrE | 0.2704 | Inherited |
| BRCT domain | 0.2769 | Inherited |
| Bromodomain | 0.2967 | Inherited |
| 6-phosphogluconate dehydrogenase C-terminal domain-like | 0.2967 | Inherited |
| Nucleotidylyl transferase | 0.3189 | Inherited |
| Cysteine proteinases | 0.3196 | Inherited |
| SNARE-like | 0.3263 | Inherited |
| POZ domain | 0.3279 | Inherited |
| Ribosomal protein S5 domain 2-like | 0.3356 | Inherited |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0.3414 | Inherited |
| SAM/Pointed domain | 0.3415 | Inherited |
| Lipocalins | 0.3417 | Inherited |
| UDP-Glycosyltransferase/glycogen phosphorylase | 0.3518 | Inherited |
| Nicotinic receptor ligand binding domain-like | 0.3914 | Inherited |
| Translation proteins SH3-like domain | 0.3929 | Inherited |
| Cation efflux protein transmembrane domain-like | 0.3929 | Inherited |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.415 | Inherited |
| Acid proteases | 0.419 | Inherited |
| Cysteine-rich domain | 0.4435 | Inherited |
| FYVE/PHD zinc finger | 0.446 | Inherited |
| Ubiquitin-like | 0.4719 | Inherited |
| RNA-binding domain, RBD | 0.4786 | Inherited |
| HAD-like | 0.5055 | Inherited |
| PRTase-like | 0.5166 | Inherited |
| DHS-like NAD/FAD-binding domain | 0.5166 | Inherited |
| Myosin rod fragments | 0.5166 | Inherited |
| t-snare proteins | 0.5166 | Inherited |
| Voltage-gated potassium channels | 0.5505 | Inherited |
| Ferredoxin reductase-like, C-terminal NADP-linked domain | 0.5638 | Inherited |
| Riboflavin synthase domain-like | 0.5638 | Inherited |
| Cystine-knot cytokines | 0.572 | Inherited |
| WW domain | 0.572 | Inherited |
| Sm-like ribonucleoproteins | 0.572 | Inherited |
| FAD-linked reductases, C-terminal domain | 0.572 | Inherited |
| FAD/NAD(P)-binding domain | 0.6087 | Inherited |
| Seven-hairpin glycosidases | 0.615 | Inherited |
| SET domain | 0.6155 | Inherited |
| UBC-like | 0.6387 | Inherited |
| MFS general substrate transporter | 0.6496 | Inherited |
| Clavaminate synthase-like | 0.6536 | Inherited |
| Nucleotide-binding domain | 0.6706 | Inherited |
| Lipovitellin-phosvitin complex, superhelical domain | 0.6706 | Inherited |
| KA1-like | 0.6706 | Inherited |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0.6706 | Inherited |
| Osmotin, thaumatin-like protein | 0.6706 | Inherited |
| Rhodanese/Cell cycle control phosphatase | 0.6764 | Inherited |
| S15/NS1 RNA-binding domain | 0.732 | Inherited |
| Glucocorticoid receptor-like (DNA-binding domain) | 0.769 | Inherited |
| GST C-terminal domain-like | 0.772 | Inherited |
| Ribonuclease H-like | 0.7826 | Inherited |
| alpha/beta-Hydrolases | 0.7829 | Inherited |
| PAZ domain | 0.7862 | Inherited |
| ADC-like | 0.7982 | Inherited |
| MIT domain | 0.7982 | Inherited |
| Fibronectin type III | 0.848 | Inherited |
| UBA-like | 0.9001 | Inherited |
| Leucine zipper domain | 0.9025 | Inherited |
| GTPase activation domain, GAP | 0.9142 | Inherited |
| EF-hand | 0.9198 | Inherited |
| p53-like transcription factors | 0.9665 | Inherited |
| Ribonuclease PH domain 2-like | 0.9724 | Inherited |
| Immunoglobulin | 0.9976 | Inherited |
| Family A G protein-coupled receptor-like | 1 | Inherited |
| Ligand-binding domain in the NO signalling and Golgi transport | 1 | Inherited |
| Saposin | 1 | Inherited |
| Cyclophilin-like | 1 | Inherited |
| beta-beta-alpha zinc fingers | 1 | Inherited |
| Nuclear receptor ligand-binding domain | 1 | Inherited |
| F-box domain | 1 | Inherited |
| Bet v1-like | 1 | Inherited |
| FKBP-like | 1 | Inherited |
| B-box zinc-binding domain | 1 | Inherited |
| Eukaryotic type KH-domain (KH-domain type I) | 1 | Inherited |
| Thioredoxin-like | 1 | Inherited |
| RING/U-box | 1 | Inherited |
| CoA-dependent acyltransferases | 1 | Inherited |
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Family(show details)
Family domains annotated to this WP term (Not in SDWP)
Highlighted in gray are those with FDR_all>0.001
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| PhzC/PhzF-like | 0 | DIRECT |
| Poly(A) polymerase, PAP, middle domain | 0 | DIRECT |
| Acylamino-acid-releasing enzyme, C-terminal donain | 0 | DIRECT |
| Phosphoribosyltransferases (PRTases) | 0 | DIRECT |
| Aminoacid dehydrogenase-like, C-terminal domain | 0 | DIRECT |
| Phoshoinositide 3-kinase (PI3K) helical domain | 0 | DIRECT |
| Rap/Ran-GAP | 0 | DIRECT |
| PUA domain | 0 | DIRECT |
| Tandem AAA-ATPase domain | 0 | DIRECT |
| YbiA-like | 0 | DIRECT |
| Epoxide hydrolase | 0 | DIRECT |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | DIRECT |
| DPP6 N-terminal domain-like | 0 | DIRECT |
| Ribonucleotide reductase-like | 0 | DIRECT |
| Spectrin repeat | 0 | DIRECT |
| Choline kinase | 0 | DIRECT |
| Laminin G-like module | 0 | DIRECT |
| CO dehydrogenase flavoprotein N-terminal domain-like | 0 | DIRECT |
| YicI catalytic domain-like | 0 | DIRECT |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Nucleoside diphosphate kinase, NDK | 0 | DIRECT |
| 2Fe-2S ferredoxin domains from multidomain proteins | 0 | DIRECT |
| Band 7/SPFH domain | 0 | DIRECT |
| FF domain | 0 | DIRECT |
| Reprolysin-like | 0 | DIRECT |
| HSP20 | 0 | DIRECT |
| Second domain of FERM | 0 | DIRECT |
| EGF-type module | 0 | DIRECT |
| CO dehydrogenase molybdoprotein N-domain-like | 0 | DIRECT |
| Branched-chain alpha-keto acid dehydrogenase PP module | 0 | DIRECT |
| Glutaminase | 0 | DIRECT |
| Heme-dependent catalases | 0 | DIRECT |
| Adenain-like | 0 | DIRECT |
| Helical domain of Sec23/24 | 0 | DIRECT |
| Insulin-like | 0 | DIRECT |
| beta-sandwich domain of Sec23/24 | 0 | DIRECT |
| Cation efflux protein cytoplasmic domain-like | 0 | DIRECT |
| NTF2-like | 0 | DIRECT |
| Third domain of FERM | 0 | DIRECT |
| SCF ubiquitin ligase complex WHB domain | 0 | DIRECT |
| Histone deacetylase, HDAC | 0 | DIRECT |
| Fibrinogen C-terminal domain-like | 0 | DIRECT |
| Arfaptin, Rac-binding fragment | 0 | DIRECT |
| CoA-binding domain | 0 | DIRECT |
| Alcohol dehydrogenase-like, N-terminal domain | 0 | DIRECT |
| Molybdenum cofactor-binding domain | 0 | DIRECT |
| DNA replication initiator (cdc21/cdc54) N-terminal domain | 0 | DIRECT |
| Chaperone J-domain | 0 | DIRECT |
| DNA gyrase/MutL, N-terminal domain | 0 | DIRECT |
| Ran binding protein zinc finger-like | 0 | DIRECT |
| Sec1/munc18-like (SM) proteins | 0 | DIRECT |
| Acireductone dioxygenase | 0 | DIRECT |
| SAND domain | 0 | DIRECT |
| Profilin (actin-binding protein) | 0 | DIRECT |
| Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain | 0 | DIRECT |
| Myotubularin-like phosphatases | 0 | DIRECT |
| RecA protein-like (ATPase-domain) | 0 | DIRECT |
| HAT/Suf repeat | 0 | DIRECT |
| UDP-glucose pyrophosphorylase | 0 | DIRECT |
| Serum paraoxonase/arylesterase 1, PON1 | 0 | DIRECT |
| Hypothetical protein c14orf129, hspc210 | 0 | DIRECT |
| CRAL/TRIO N-terminal domain | 0 | DIRECT |
| MutT-like | 0 | DIRECT |
| Hsp90 middle domain | 0 | DIRECT |
| AAT-like | 0 | DIRECT |
| Purine and uridine phosphorylases | 0 | DIRECT |
| HEAT repeat | 0 | DIRECT |
| Inositol polyphosphate 5-phosphatase (IPP5) | 0 | DIRECT |
| GAS2 domain | 0 | DIRECT |
| Methionine aminopeptidase, insert domain | 0 | DIRECT |
| Acyl-CoA thioesterase | 0 | DIRECT |
| Hect, E3 ligase catalytic domain | 0 | DIRECT |
| Brix domain | 0 | DIRECT |
| Carbonic anhydrase | 0 | DIRECT |
| Trunk domain of Sec23/24 | 0 | DIRECT |
| Matrix metalloproteases, catalytic domain | 0 | DIRECT |
| Sec7 domain | 0 | DIRECT |
| Lesion bypass DNA polymerase (Y-family), catalytic domain | 0 | DIRECT |
| Annexin | 0 | DIRECT |
| Chitinase insertion domain | 0 | DIRECT |
| HSP90 C-terminal domain | 0 | DIRECT |
| Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain | 0 | DIRECT |
| Carboxypeptidase regulatory domain | 0 | DIRECT |
| Inositol monophosphatase/fructose-1,6-bisphosphatase-like | 0 | DIRECT |
| BC N-terminal domain-like | 0 | DIRECT |
| Succinyl-CoA synthetase domains | 0 | DIRECT |
| HMG-box | 0 | DIRECT |
| alpha-Amylases, C-terminal beta-sheet domain | 0 | DIRECT |
| Tetraspanin | 0 | DIRECT |
| POU-specific domain | 0 | DIRECT |
| Doublecortin (DC) | 0 | DIRECT |
| DEP domain | 0 | DIRECT |
| Group II chaperonin (CCT, TRIC), apical domain | 0 | DIRECT |
| Formate/glycerate dehydrogenases, NAD-domain | 0 | DIRECT |
| Sterol carrier protein, SCP | 0 | DIRECT |
| Lamin A/C globular tail domain | 0 | DIRECT |
| cAMP-binding domain | 0 | DIRECT |
| Pepsin inhibitor-3 | 0 | DIRECT |
| ALDH-like | 0 | DIRECT |
| Anticodon-binding domain of Class II aaRS | 0 | DIRECT |
| Biotin dependent carboxylase carboxyltransferase domain | 0 | DIRECT |
| Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | DIRECT |
| Bacterial exopeptidase dimerisation domain | 0 | DIRECT |
| Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | DIRECT |
| Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta | 0 | DIRECT |
| Pleckstrin-homology domain (PH domain) | 0 | DIRECT |
| Peptidylglycine alpha-hydroxylating monooxygenase, PHM | 0 | DIRECT |
| Ribosomal protein S10 | 0 | DIRECT |
| Cdc48 domain 2-like | 0 | DIRECT |
| RNA editing terminal uridyl transferase 2, RET2, domain 2 | 0 | DIRECT |
| PEP carboxykinase C-terminal domain | 0 | DIRECT |
| Regulator of G-protein signaling, RGS | 0 | DIRECT |
| DNA repair protein MutS, domain III | 0 | DIRECT |
| Calcium ATPase, transmembrane domain M | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
| VHS domain | 0 | DIRECT |
| Quinoprotein alcohol dehydrogenase-like | 0 | DIRECT |
| AN1-like Zinc finger | 0 | DIRECT |
| BC C-terminal domain-like | 0 | DIRECT |
| Inositol polyphosphate kinase (IPK) | 0 | DIRECT |
| PDEase | 0 | DIRECT |
| beta-Lactamase/D-ala carboxypeptidase | 0 | DIRECT |
| Amylase, catalytic domain | 0 | DIRECT |
| Adenosine/AMP deaminase | 0 | DIRECT |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Troponin I | 0 | DIRECT |
| Anticodon-binding domain | 0 | DIRECT |
| LDH N-terminal domain-like | 0 | DIRECT |
| Tim10/DDP | 0 | DIRECT |
| Cullin repeat | 0 | DIRECT |
| LacY-like proton/sugar symporter | 0 | DIRECT |
| PDI-like | 0 | DIRECT |
| Alcohol dehydrogenase-like, C-terminal domain | 0 | DIRECT |
| Sec63 C-terminal domain-like | 0 | DIRECT |
| WWE domain | 0 | DIRECT |
| Aquaporin-like | 0 | DIRECT |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | DIRECT |
| Sec63 N-terminal domain | 0 | DIRECT |
| Ngr ectodomain-like | 0 | DIRECT |
| SMAD domain | 0 | DIRECT |
| Translational machinery components | 0 | DIRECT |
| HD domain | 0 | DIRECT |
| Protein prenyltransferases | 0 | DIRECT |
| GAPDH-like | 0 | DIRECT |
| Internalin LRR domain | 0 | DIRECT |
| Hydantoinase (dihydropyrimidinase) | 0 | DIRECT |
| Glycosyl transferases group 1 | 0 | DIRECT |
| ets domain | 0 | DIRECT |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
| Double-stranded RNA-binding domain (dsRBD) | 0 | DIRECT |
| DNA gyrase/MutL, second domain | 0 | DIRECT |
| ValRS/IleRS/LeuRS editing domain | 0 | DIRECT |
| alpha-catenin/vinculin | 0 | DIRECT |
| Dimeric isocitrate & isopropylmalate dehydrogenases | 0 | DIRECT |
| Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains | 0 | DIRECT |
| Ribokinase-like | 0 | DIRECT |
| Heat shock protein 90, HSP90, N-terminal domain | 0 | DIRECT |
| Ubiquitin carboxyl-terminal hydrolase UCH-L | 0 | DIRECT |
| Small-conductance potassium channel | 0 | DIRECT |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
| Proteasome subunits | 0 | DIRECT |
| 5' to 3' exonuclease catalytic domain | 0 | DIRECT |
| Arylsulfatase | 0 | DIRECT |
| Clathrin adaptor core protein | 0 | DIRECT |
| Chromo domain | 0 | DIRECT |
| Group II chaperonin (CCT, TRIC), ATPase domain | 0 | DIRECT |
| NHL repeat | 0 | DIRECT |
| FHA domain | 0 | DIRECT |
| Calpain large subunit, catalytic domain (domain II) | 0 | DIRECT |
| Ribosomal protein L18 and S11 | 0 | DIRECT |
| Intermediate filament protein, coiled coil region | 0 | DIRECT |
| DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
| L30e/L7ae ribosomal proteins | 0 | DIRECT |
| Class I glutamine amidotransferases (GAT) | 0 | DIRECT |
| Ovomucoid domain III-like | 0 | DIRECT |
| Mitochondrial carrier | 0 | DIRECT |
| Blood coagulation inhibitor (disintegrin) | 0 | DIRECT |
| Glycerophosphoryl diester phosphodiesterase | 0 | DIRECT |
| Hormone receptor domain | 0 | DIRECT |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | DIRECT |
| FtsH protease domain-like | 0 | DIRECT |
| SAM (sterile alpha motif) domain | 0 | DIRECT |
| SMAD MH1 domain | 0 | DIRECT |
| XPF/Rad1/Mus81 nuclease | 0 | DIRECT |
| Actin/HSP70 | 0 | DIRECT |
| Sir2 family of transcriptional regulators | 0 | DIRECT |
| Pancreatic carboxypeptidase, activation domain | 0 | DIRECT |
| Poly(A) polymerase, PAP, C-terminal domain | 0 | DIRECT |
| CUT domain | 0 | DIRECT |
| Glycerol kinase | 0 | DIRECT |
| Armadillo repeat | 0 | DIRECT |
| Cadherin | 0 | DIRECT |
| Nucleosome core histones | 0 | DIRECT |
| Cyclin | 0 | DIRECT |
| Thyroglobulin type-1 domain | 0 | DIRECT |
| Skp1 dimerisation domain-like | 0 | DIRECT |
| L-aminoacid/polyamine oxidase | 0 | DIRECT |
| Arginine methyltransferase | 0 | DIRECT |
| Cofilin-like | 0 | DIRECT |
| WGR domain | 0 | DIRECT |
| Regulator of chromosome condensation RCC1 | 0 | DIRECT |
| MIF4G domain-like | 0 | DIRECT |
| Nop domain | 0 | DIRECT |
| Branched-chain alpha-keto acid dehydrogenase Pyr module | 0 | DIRECT |
| Polo-box duplicated region | 0 | DIRECT |
| acyl-CoA oxidase N-terminal domains | 0 | DIRECT |
| Single strand DNA-binding domain, SSB | 0 | DIRECT |
| MFPT repeat | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
| AMPK-beta glycogen binding domain-like | 0 | DIRECT |
| D-aminoacid oxidase-like | 0 | DIRECT |
| Clc chloride channel | 0 | DIRECT |
| PEP carboxykinase N-terminal domain | 0 | DIRECT |
| Subtilases | 0 | DIRECT |
| Cytoplasmic domain of inward rectifier potassium channel | 0 | DIRECT |
| Proton glutamate symport protein | 0 | DIRECT |
| IF2B-like | 0 | DIRECT |
| Clathrin coat assembly domain | 0 | DIRECT |
| beta 1,4 galactosyltransferase (b4GalT1) | 0 | DIRECT |
| 28-residue LRR | 0 | DIRECT |
| Transducin (heterotrimeric G protein), gamma chain | 0 | DIRECT |
| BEACH domain | 0 | DIRECT |
| Hedgehog C-terminal (Hog) autoprocessing domain | 0 | DIRECT |
| Mammalian PLC | 0 | DIRECT |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
| CAT-like | 0 | DIRECT |
| Ribosomal protein L1 | 0 | DIRECT |
| Fatty acid binding protein-like | 0 | DIRECT |
| NOL1/NOP2/sun | 0 | DIRECT |
| Proprotein convertase P-domain | 0 | DIRECT |
| F1F0 ATP synthase subunit C | 0 | DIRECT |
| Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain | 0 | DIRECT |
| MIR domain | 0 | DIRECT |
| Phosphate binding protein-like | 0 | DIRECT |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | DIRECT |
| RNA-polymerase beta-prime | 0 | DIRECT |
| Oxysterol-binding protein | 0 | DIRECT |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
| PABC (PABP) domain | 0 | DIRECT |
| BAR domain | 0 | DIRECT |
| Tubulin, GTPase domain | 0 | DIRECT |
| Pancreatic carboxypeptidases | 0 | DIRECT |
| Integrin domains | 0 | DIRECT |
| PLC-like (P variant) | 0 | DIRECT |
| Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | DIRECT |
| D-aminoacid oxidase, N-terminal domain | 0 | DIRECT |
| YWTD domain | 0 | DIRECT |
| Lactate & malate dehydrogenases, C-terminal domain | 0 | DIRECT |
| Phoshoinositide 3-kinase (PI3K), catalytic domain | 0 | DIRECT |
| GHMP Kinase, N-terminal domain | 0 | DIRECT |
| Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain | 0 | DIRECT |
| ARID domain | 0 | DIRECT |
| Cullin homology domain | 0 | DIRECT |
| Translation initiation factor eIF4e | 0 | DIRECT |
| Hexokinase | 0 | DIRECT |
| RNA-polymerase beta | 0 | DIRECT |
| Smc hinge domain | 0 | DIRECT |
| Crotonase-like | 0 | DIRECT |
| BC ATP-binding domain-like | 0 | DIRECT |
| Phosphatidylethanolamine binding protein | 0 | DIRECT |
| HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
| MOSC N-terminal domain-like | 0 | DIRECT |
| Cu,Zn superoxide dismutase-like | 0 | DIRECT |
| Paired domain | 0 | DIRECT |
| Pyk2-associated protein beta ARF-GAP domain | 0 | DIRECT |
| RhoGDI-like | 0 | DIRECT |
| SWIB/MDM2 domain | 0 | DIRECT |
| PurM C-terminal domain-like | 0 | DIRECT |
| Myeloperoxidase-like | 0 | DIRECT |
| Citrate synthase | 0 | DIRECT |
| Erythroid transcription factor GATA-1 | 0 | DIRECT |
| Class I aldolase | 0 | DIRECT |
| U-box | 0 | DIRECT |
| Complement control module/SCR domain | 0 | DIRECT |
| DPP6 catalytic domain-like | 0 | DIRECT |
| Phosphoglucomutase, first 3 domains | 0 | DIRECT |
| Zn-finger domain of Sec23/24 | 0 | DIRECT |
| Ras-binding domain, RBD | 0 | DIRECT |
| Gamma-glutamyltranspeptidase-like | 0 | DIRECT |
| COMT-like | 0 | DIRECT |
| Transducin (alpha subunit), insertion domain | 0 | DIRECT |
| La domain | 0 | DIRECT |
| Bactericidal permeability-increasing protein, BPI | 0 | DIRECT |
| LysM domain | 0 | DIRECT |
| SWIRM domain | 0 | DIRECT |
| FAD-dependent thiol oxidase | 0 | DIRECT |
| Domain of poly(ADP-ribose) polymerase | 0 | DIRECT |
| ATP-dependent protease Lon (La), catalytic domain | 0 | DIRECT |
| 14-3-3 protein | 0 | DIRECT |
| AlkB-like | 0 | DIRECT |
| Cell cycle control phosphatase, catalytic domain | 0 | DIRECT |
| Glycogenin | 0 | DIRECT |
| UBA domain | 0 | DIRECT |
| Glycolipid transfer protein, GLTP | 0 | DIRECT |
| p120GAP domain-like | 0 | DIRECT |
| Medium chain acyl-CoA dehydrogenase-like, C-terminal domain | 0 | DIRECT |
| Type II chitinase | 0 | DIRECT |
| Poly(ADP-ribose) polymerase, C-terminal domain | 0 | DIRECT |
| Type II DNA topoisomerase | 0 | DIRECT |
| Group II chaperonin (CCT, TRIC), intermediate domain | 0 | DIRECT |
| GYF domain | 0 | DIRECT |
| Surp module (SWAP domain) | 0 | DIRECT |
| acyl-CoA oxidase C-terminal domains | 0 | DIRECT |
| Elafin-like | 0 | DIRECT |
| CO dehydrogenase ISP C-domain like | 0 | DIRECT |
| Poly(A) polymerase, PAP, N-terminal domain | 0 | DIRECT |
| DEATH domain, DD | 0 | DIRECT |
| Linker histone H1/H5 | 0 | DIRECT |
| Acyl-carrier protein (ACP) | 0 | DIRECT |
| a tRNA synthase domain | 0 | DIRECT |
| Ferredoxin reductase FAD-binding domain-like | 0 | DIRECT |
| Hydantoinase (dihydropyrimidinase), catalytic domain | 0 | DIRECT |
| First domain of FERM | 0 | DIRECT |
| Phosphotyrosine-binding domain (PTB) | 0 | DIRECT |
| 1,3-glucuronyltransferase | 0 | DIRECT |
| LEM domain | 0 | DIRECT |
| Class II glutamine amidotransferases | 0 | DIRECT |
| PDZ domain | 0 | DIRECT |
| PurM N-terminal domain-like | 0 | DIRECT |
| Tubulin, C-terminal domain | 0 | DIRECT |
| HCDH C-domain-like | 0 | DIRECT |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
| Biotinyl/lipoyl-carrier proteins and domains | 0 | DIRECT |
| S-adenosylmethionine synthetase | 0 | DIRECT |
| Thiolase-related | 0 | DIRECT |
| Ubiquitin activating enzymes (UBA) | 0 | DIRECT |
| Reductases | 0 | DIRECT |
| PaaI/YdiI-like | 0 | DIRECT |
| Protein kinases, catalytic subunit | 0.01525 | INHERITED FROM: copper response variant || alkaline pH chemotaxis variant || kinase activity reduced || aldicarb response variant || protein subcellular localization variant || protein phosphorylation reduced || conflicting sensory integration variant || protein phosphorylation variant || dauer induction variant || egg laying response to food variant || pathogen induced gene expression variant || octanol chemotaxis defective || organism environmental stimulus response variant || positive chemotaxis variant || chemotaxis variant || anoxia resistant || protein expression variant || protein modification variant || drug induced gene expression variant || chemical response variant || lipid synthesis increased || antimicrobial gene expression variant |
| WD40-repeat | 0.03027 | INHERITED FROM: organism metabolism processing variant || late larval arrest || dauer defective || protein aggregation induced behavior variant |
| G proteins | 0.0401 | INHERITED FROM: osmotic integrity variant || organism metabolism processing variant || aldicarb response variant || protein phosphorylation variant || carbon dioxide response variant || organism environmental stimulus response variant || bacterially unswollen || carbon dioxide avoidance variant || drug induced gene expression variant || fat content variant |
| ABC transporter ATPase domain-like | 0.04592 | INHERITED FROM: cadmium response variant || RNAi response variant || metal response variant || colchicine hypersensitive |
| Homeodomain | 0.04622 | INHERITED FROM: organism metabolism processing variant || carbon dioxide response variant || sexually dimorphic physiology variant || carbon dioxide avoidance variant || level of transgene expression variant |
| MSP-like | 0.07283 | INHERITED FROM: dauer lifespan variant || larval growth variant || lipid metabolism variant || dauer metabolism variant || slow growth || dauer lifespan extended || larval arrest || fat content variant || developmental growth variant |
| L-arabinose binding protein-like | 0.07372 | INHERITED FROM: anion positive chemotaxis variant || alkaline pH chemotaxis variant || magnesium chemotaxis defective || bromide chemotaxis variant || chemosensory response variant || anion positive chemotaxis defective || organism environmental stimulus response variant || iodide chemotaxis defective || bromide chemotaxis defective || cation positive chemotaxis defective || chemotaxis variant || lithium chemotaxis defective || iodide chemotaxis variant || cation positive chemotaxis variant |
| SH2 domain | 0.07455 | INHERITED FROM: protein expression reduced || level of protein expression variant || protein expression variant |
| Acetyl-CoA synthetase-like | 0.08884 | INHERITED FROM: lipid metabolism variant |
| CCCH zinc finger | 0.1175 | INHERITED FROM: mRNA expression ectopic || gene expression variant || transgene expression variant || ectopic expression transgene |
| Tetratricopeptide repeat (TPR) | 0.1363 | INHERITED FROM: organism metabolism processing variant || antibody subcellular localization variant |
| Cold shock DNA-binding domain-like | 0.1549 | INHERITED FROM: mRNA surveillance defective || sick || nonsense mRNA accumulation |
| HLH, helix-loop-helix DNA-binding domain | 0.17 | INHERITED FROM: gene expression level reduced || hypoxia response variant || lysine chemotaxis defective || RNA expression variant || ectopic expression transgene || aqueous positive chemotaxis defective |
| Adenylyl and guanylyl cyclase catalytic domain | 0.17 | INHERITED FROM: osmotic avoidance variant || second messenger mediated signaling variant || alkaline pH chemotaxis variant || magnesium chemotaxis defective || metabolic pathway variant || diacetyl chemotaxis variant || carbon dioxide response variant || bromide chemotaxis variant || chemosensory response variant || anion positive chemotaxis defective || organism environmental stimulus response variant || AWC odorant chemotaxis defective || positive chemotaxis variant || iodide chemotaxis defective || bromide chemotaxis defective || cation positive chemotaxis defective || chemotaxis variant || AWC odorant chemotaxis variant || lithium chemotaxis defective || iodide chemotaxis variant |
| Ankyrin repeat | 0.1858 | INHERITED FROM: octanol chemotaxis variant || odorant negative chemotaxis defective || octanol chemotaxis defective || organism heat response variant || chemotaxis variant |
| Calcium ATPase, transduction domain A | 0.2038 | INHERITED FROM: drug hypersensitive || organism environmental stimulus response variant || nicotine hypersensitive |
| Canonical RBD | 0.2092 | INHERITED FROM: starvation induced apoptosis variant || late larval arrest || RNA processing variant || sick || RNA expression variant || mRNA export variant |
| ABC transporter transmembrane region | 0.2256 | INHERITED FROM: cadmium response variant || RNAi response variant || organism environmental stimulus response variant || metal response variant || colchicine hypersensitive |
| Histone lysine methyltransferases | 0.2437 | INHERITED FROM: life span variant || RNAi response variant || protein methylation variant || maintenance of gene silencing variant || histone methylation variant || mRNA expression variant || protein expression variant || protein modification variant || ectopic expression antibody || somatic transgene silencing variant || ectopic expression transgene |
| Pepsin-like | 0.2437 | INHERITED FROM: hypoosmotic shock hypersensitive || osmotic integrity variant || organism metabolism processing variant || gene expression variant || transgene subcellular localization variant || transgene expression variant || protein interaction variant || pattern of transgene expression variant || protein aggregation variant || protein protein interaction variant |
| Class I aminoacyl-tRNA synthetases (RS), catalytic domain | 0.2437 | INHERITED FROM: organism metabolism processing variant || gene expression variant || mRNA surveillance defective || transgene expression increased || hypoxia response variant || RNA processing variant || organism environmental stimulus response variant || nonsense mRNA accumulation || paraquat resistant || oxygen response variant || paraquat response variant || hypoxia resistant |
| DBL homology domain (DH-domain) | 0.2437 | INHERITED FROM: aldicarb response variant || organism pathogen response variant || organism environmental stimulus response variant || bacterially unswollen || pathogen resistance increased |
| Extended PAW domain | 0.2437 | INHERITED FROM: transgene subcellular localization variant || protein interaction variant || pattern of transgene expression variant || protein aggregation variant || protein protein interaction variant |
| Elongation factors | 0.2437 | INHERITED FROM: protein phosphorylation increased || protein phosphorylation variant || mRNA levels increased || mRNA levels reduced || protein modification variant || protein aggregation variant || protein protein interaction variant |
| SH3-domain | 0.2533 | INHERITED FROM: protein expression reduced || protein expression variant |
| Dual specificity phosphatase-like | 0.2667 | INHERITED FROM: organism metabolism processing variant || transgene expression reduced || gene expression variant || level of transgene expression variant |
| Acetylcholinesterase-like | 0.2672 | INHERITED FROM: enzyme activity reduced || acetylcholinesterase reduced || acetylcholinesterase activity variant || enzyme activity variant |
| Metal cation-transporting ATPase, ATP-binding domain N | 0.2912 | INHERITED FROM: drug hypersensitive || organism environmental stimulus response variant || nicotine hypersensitive |
| Multidrug efflux transporter AcrB transmembrane domain | 0.3162 | INHERITED FROM: odorant positive chemotaxis defective || positive chemotaxis defective || embryo osmotic integrity defective early emb || odorant chemosensory response variant || egg integrity defective early emb || chemotaxis variant |
| 6-phosphogluconate dehydrogenase-like, N-terminal domain | 0.3182 | INHERITED FROM: lipid metabolism variant || fat content variant |
| FYVE, a phosphatidylinositol-3-phosphate binding domain | 0.3182 | INHERITED FROM: acetylcholinesterase inhibitor resistant || aldicarb resistant |
| Bromodomain | 0.3182 | INHERITED FROM: drug adaptation variant || acute functional tolerance to alcohol defective || anesthetic resistant || anesthetic response variant || organism UV hypersensitive || sick || organism UV response variant || ethanol resistant |
| Extended AAA-ATPase domain | 0.3346 | INHERITED FROM: sick || protein expression increased || shortened life span |
| Cytochrome P450 | 0.3427 | INHERITED FROM: cadmium response variant || metal response variant |
| FAD/NAD-linked reductases, N-terminal and central domains | 0.3476 | INHERITED FROM: pesticide response variant || organism oxidative stress response variant || paraquat response variant |
| Meta-cation ATPase, catalytic domain P | 0.3795 | INHERITED FROM: organism environmental stimulus response variant || nicotine hypersensitive |
| Sm motif of small nuclear ribonucleoproteins, SNRNP | 0.3795 | INHERITED FROM: pattern protein expression variant || protein subcellular localization variant || pattern of transgene expression variant || sick || shortened life span || protein aggregation variant || protein protein interaction variant |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.4205 | INHERITED FROM: hypoosmotic shock hypersensitive || sodium chloride chemotaxis variant || mechanosensation variant || aqueous chemosensory response variant || selenium response variant || nicotine resistant || organism environmental stimulus response variant || drug response variant || antihelmintic response variant || DMPP response variant || cholinergic agonist resistant || chemical response variant |
| Pumilio repeat | 0.4499 | INHERITED FROM: protein expression ectopic |
| GABA-aminotransferase-like | 0.4499 | INHERITED FROM: fat content reduced |
| Protein kinase cysteine-rich domain (cys2, phorbol-binding domain) | 0.488 | INHERITED FROM: odorant positive chemotaxis variant || organism metabolism processing variant || protein subcellular localization variant || organism pathogen response variant || innate immune response variant || odorant chemosensory response variant || nose touch variant || drug induced gene expression variant || antimicrobial gene expression variant || drug resistant |
| Cation efflux protein transmembrane domain-like | 0.4906 | INHERITED FROM: cadmium response variant || cadmium hypersensitive || metal response variant |
| Nicotinic receptor ligand binding domain-like | 0.4951 | INHERITED FROM: hypoosmotic shock hypersensitive || sodium chloride chemotaxis variant || mechanosensation variant || aqueous chemosensory response variant || selenium response variant || nicotine resistant || organism environmental stimulus response variant || drug response variant || antihelmintic response variant || DMPP response variant || cholinergic agonist resistant || chemical response variant |
| Glutathione S-transferase (GST), N-terminal domain | 0.506 | INHERITED FROM: enzyme activity reduced || cadmium response variant || organism stress response variant || organism heat hypersensitive || cadmium hypersensitive || organism environmental stimulus response variant || organism electrophilic stress hypersensitive || paraquat response variant || enzyme activity variant |
| PHD domain | 0.5158 | INHERITED FROM: RNAi response variant || protein methylation variant || organism UV hypersensitive || RNAi resistant || organism UV response variant || ectopic expression transgene |
| t-snare proteins | 0.5344 | INHERITED FROM: drug hypersensitive |
| Pyridoxal-dependent decarboxylase | 0.5344 | INHERITED FROM: egg laying response to drug variant || carbon dioxide response variant || drug response variant || carbon dioxide avoidance variant |
| Myosin rod fragments | 0.5344 | INHERITED FROM: drug resistant |
| I set domains | 0.5776 | INHERITED FROM: growth rate variant || aldicarb response variant || organism environmental stimulus response variant || aldicarb resistant |
| Gastric lipase | 0.58 | INHERITED FROM: lipid metabolism variant || fat content variant |
| Myb/SANT domain | 0.58 | INHERITED FROM: growth rate variant |
| Papain-like | 0.5978 | INHERITED FROM: hypoosmotic shock hypersensitive || osmotic integrity variant || organism metabolism processing variant || gene expression variant || transgene expression variant || protein interaction variant || pattern of transgene expression variant || protein aggregation variant || protein protein interaction variant |
| WW domain | 0.608 | INHERITED FROM: maintenance of gene silencing variant |
| Class I alpha-1;2-mannosidase, catalytic domain | 0.6302 | INHERITED FROM: extended life span || protein aggregation variant || protein protein interaction variant |
| UBC-related | 0.6509 | INHERITED FROM: organism metabolism processing variant || late larval arrest || gene expression variant || transgene subcellular localization variant || transgene expression variant || protein interaction variant || pattern of transgene expression variant || protein aggregation variant || protein protein interaction variant |
| Osmotin, thaumatin-like protein | 0.6854 | INHERITED FROM: cadmium response variant || cadmium hypersensitive || metal response variant |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0.6854 | INHERITED FROM: life span variant || organism pathogen response variant || pathogen susceptibility increased || organism environmental stimulus response variant |
| Lipovitellin-phosvitin complex, superhelical domain | 0.6854 | INHERITED FROM: life span variant || organism pathogen response variant || pathogen susceptibility increased || organism environmental stimulus response variant |
| Ubiquitin carboxyl-terminal hydrolase, UCH | 0.7037 | INHERITED FROM: organism metabolism processing variant || gene expression variant || transgene expression variant || protein interaction variant || pattern of transgene expression variant || protein aggregation variant || protein protein interaction variant |
| Synaptotagmin-like (S variant) | 0.7106 | INHERITED FROM: pattern protein expression variant || protein subcellular localization variant || acetylcholinesterase inhibitor response variant || acetylcholinesterase inhibitor resistant || drug resistant |
| Growth factor receptor domain | 0.7106 | INHERITED FROM: chemotaxis variant |
| BTB/POZ domain | 0.7211 | INHERITED FROM: early larval arrest || resistant to protein aggregation induced paralysis || chemical hypersensitive || protein aggregation induced behavior variant || L1 arrest || chemical response variant |
| EF-hand modules in multidomain proteins | 0.744 | INHERITED FROM: protein expression variant |
| Transforming growth factor (TGF)-beta | 0.744 | INHERITED FROM: transgene expression reduced || nicotine response variant || drug response variant || level of transgene expression variant || levamisole response variant |
| Voltage-gated potassium channels | 0.779 | INHERITED FROM: AWA odorant chemotaxis variant || growth rate variant || adrenergic receptor antagonist response variant || serotonin response variant |
| H-NOX domain | 0.806 | INHERITED FROM: carbon dioxide response variant || carbon dioxide avoidance variant |
| Bacterial lipase | 0.806 | INHERITED FROM: lipid metabolism variant || fat content variant |
| MIT domain | 0.806 | INHERITED FROM: protein interaction variant || protein aggregation variant || protein protein interaction variant |
| Cdc48 N-terminal domain-like | 0.806 | INHERITED FROM: protein interaction variant || protein aggregation variant || protein protein interaction variant |
| Ubiquitin-related | 0.8131 | INHERITED FROM: organism metabolism processing variant || transgene expression variant || protein interaction variant || hypersensitive to protein aggregation induced paralysis || protein aggregation variant || protein protein interaction variant |
| FAD-linked reductases, N-terminal domain | 0.8501 | INHERITED FROM: shortened life span |
| PAZ domain | 0.8768 | INHERITED FROM: RNAi enhanced || RNAi response variant || siRNA expression variant || mRNA levels increased || maintenance of gene silencing variant || RNA expression variant || 21U RNA expression variant |
| LIM domain | 0.8855 | INHERITED FROM: protein expression reduced || level of protein expression variant |
| Glutathione S-transferase (GST), C-terminal domain | 0.9107 | INHERITED FROM: enzyme activity reduced || cadmium response variant || organism stress response variant || cadmium hypersensitive || organism environmental stimulus response variant || organism electrophilic stress hypersensitive || enzyme activity variant |
| Leucine zipper domain | 0.9356 | INHERITED FROM: transgene expression reduced || organism pathogen response variant || pore forming toxin response variant || mRNA levels reduced || level of transgene expression variant |
| Nuclear receptor ligand-binding domain | 0.9483 | INHERITED FROM: lipid metabolism variant || transgene expression reduced || dauer resistance to harsh conditions variant || gene expression level reduced || chemical hypersensitive || gene expression level high || SDS sensitive dauer || fat content increased |
| Calmodulin-like | 0.9527 | INHERITED FROM: transgene subcellular localization variant || protein interaction variant || protein aggregation variant || protein protein interaction variant |
| DnaQ-like 3'-5' exonuclease | 0.9569 | INHERITED FROM: RNAi response variant |
| NagD-like | 0.9817 | INHERITED FROM: dauer formation variant || dauer constitutive |
| Ribonuclease PH domain 2-like | 0.9817 | INHERITED FROM: early larval arrest |
| Ribonuclease PH domain 1-like | 0.9817 | INHERITED FROM: early larval arrest |
| F-box domain | 1 | INHERITED FROM: resistant to protein aggregation induced paralysis || protein aggregation induced behavior variant |
| RING finger domain, C3HC4 | 1 | INHERITED FROM: organism metabolism processing variant || transgene subcellular localization variant || protein interaction variant || pattern of transgene expression variant || protein aggregation variant || protein protein interaction variant |
| FKBP immunophilin/proline isomerase | 1 | INHERITED FROM: transgene subcellular localization variant || protein interaction variant || pattern of transgene expression variant || protein aggregation variant || protein protein interaction variant |
| N-acetyl transferase, NAT | 1 | INHERITED FROM: ectopic expression transgene |
| Cyclophilin (peptidylprolyl isomerase) | 1 | INHERITED FROM: transgene subcellular localization variant || transgene expression variant || protein interaction variant || pattern of transgene expression variant || protein aggregation variant || protein protein interaction variant |
| Nuclear receptor | 1 | INHERITED FROM: transgene expression reduced || dauer resistance to harsh conditions variant || SDS sensitive dauer || fat content increased |
| B-box zinc-binding domain | 1 | INHERITED FROM: gene expression variant || transgene subcellular localization variant || transgene expression variant || protein interaction variant || protein aggregation variant || protein protein interaction variant |
| Choline/Carnitine O-acyltransferase | 1 | INHERITED FROM: lipid metabolism variant || fat content variant |
| Rhodopsin-like | 1 | INHERITED FROM: aqueous adaptation defective || egg laying response to drug variant || organism pathogen response variant || locomotion rate serotonin variant || serotonin induced fat reduction variant || serotonin hypersensitive || male tail curling serotonin variant || drug withdrawal response variant || serotonin response variant || serotonin induced pumping variant || serotonin resistant || biogenic amine receptor antagonist resistant |
| Glutathione peroxidase-like | 1 | INHERITED FROM: pesticide response variant || paraquat response variant |
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| PhzC/PhzF-like | 0 | Direct |
| Poly(A) polymerase, PAP, middle domain | 0 | Direct |
| Acylamino-acid-releasing enzyme, C-terminal donain | 0 | Direct |
| Phosphoribosyltransferases (PRTases) | 0 | Direct |
| Aminoacid dehydrogenase-like, C-terminal domain | 0 | Direct |
| Phoshoinositide 3-kinase (PI3K) helical domain | 0 | Direct |
| Rap/Ran-GAP | 0 | Direct |
| PUA domain | 0 | Direct |
| Tandem AAA-ATPase domain | 0 | Direct |
| YbiA-like | 0 | Direct |
| Epoxide hydrolase | 0 | Direct |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | Direct |
| DPP6 N-terminal domain-like | 0 | Direct |
| Ribonucleotide reductase-like | 0 | Direct |
| Spectrin repeat | 0 | Direct |
| Choline kinase | 0 | Direct |
| Laminin G-like module | 0 | Direct |
| CO dehydrogenase flavoprotein N-terminal domain-like | 0 | Direct |
| YicI catalytic domain-like | 0 | Direct |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Nucleoside diphosphate kinase, NDK | 0 | Direct |
| 2Fe-2S ferredoxin domains from multidomain proteins | 0 | Direct |
| Band 7/SPFH domain | 0 | Direct |
| FF domain | 0 | Direct |
| Reprolysin-like | 0 | Direct |
| HSP20 | 0 | Direct |
| Second domain of FERM | 0 | Direct |
| EGF-type module | 0 | Direct |
| CO dehydrogenase molybdoprotein N-domain-like | 0 | Direct |
| Branched-chain alpha-keto acid dehydrogenase PP module | 0 | Direct |
| Glutaminase | 0 | Direct |
| Heme-dependent catalases | 0 | Direct |
| Adenain-like | 0 | Direct |
| Helical domain of Sec23/24 | 0 | Direct |
| Insulin-like | 0 | Direct |
| beta-sandwich domain of Sec23/24 | 0 | Direct |
| Cation efflux protein cytoplasmic domain-like | 0 | Direct |
| NTF2-like | 0 | Direct |
| Third domain of FERM | 0 | Direct |
| SCF ubiquitin ligase complex WHB domain | 0 | Direct |
| Histone deacetylase, HDAC | 0 | Direct |
| Fibrinogen C-terminal domain-like | 0 | Direct |
| Arfaptin, Rac-binding fragment | 0 | Direct |
| CoA-binding domain | 0 | Direct |
| Alcohol dehydrogenase-like, N-terminal domain | 0 | Direct |
| Molybdenum cofactor-binding domain | 0 | Direct |
| DNA replication initiator (cdc21/cdc54) N-terminal domain | 0 | Direct |
| Chaperone J-domain | 0 | Direct |
| DNA gyrase/MutL, N-terminal domain | 0 | Direct |
| Ran binding protein zinc finger-like | 0 | Direct |
| Sec1/munc18-like (SM) proteins | 0 | Direct |
| Acireductone dioxygenase | 0 | Direct |
| SAND domain | 0 | Direct |
| Profilin (actin-binding protein) | 0 | Direct |
| Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain | 0 | Direct |
| Myotubularin-like phosphatases | 0 | Direct |
| RecA protein-like (ATPase-domain) | 0 | Direct |
| HAT/Suf repeat | 0 | Direct |
| UDP-glucose pyrophosphorylase | 0 | Direct |
| Serum paraoxonase/arylesterase 1, PON1 | 0 | Direct |
| Hypothetical protein c14orf129, hspc210 | 0 | Direct |
| CRAL/TRIO N-terminal domain | 0 | Direct |
| MutT-like | 0 | Direct |
| Hsp90 middle domain | 0 | Direct |
| AAT-like | 0 | Direct |
| Purine and uridine phosphorylases | 0 | Direct |
| HEAT repeat | 0 | Direct |
| Inositol polyphosphate 5-phosphatase (IPP5) | 0 | Direct |
| GAS2 domain | 0 | Direct |
| Methionine aminopeptidase, insert domain | 0 | Direct |
| Acyl-CoA thioesterase | 0 | Direct |
| Hect, E3 ligase catalytic domain | 0 | Direct |
| Brix domain | 0 | Direct |
| Carbonic anhydrase | 0 | Direct |
| Trunk domain of Sec23/24 | 0 | Direct |
| Matrix metalloproteases, catalytic domain | 0 | Direct |
| Sec7 domain | 0 | Direct |
| Lesion bypass DNA polymerase (Y-family), catalytic domain | 0 | Direct |
| Annexin | 0 | Direct |
| Chitinase insertion domain | 0 | Direct |
| HSP90 C-terminal domain | 0 | Direct |
| Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain | 0 | Direct |
| Carboxypeptidase regulatory domain | 0 | Direct |
| Inositol monophosphatase/fructose-1,6-bisphosphatase-like | 0 | Direct |
| BC N-terminal domain-like | 0 | Direct |
| Succinyl-CoA synthetase domains | 0 | Direct |
| HMG-box | 0 | Direct |
| alpha-Amylases, C-terminal beta-sheet domain | 0 | Direct |
| Tetraspanin | 0 | Direct |
| POU-specific domain | 0 | Direct |
| Doublecortin (DC) | 0 | Direct |
| DEP domain | 0 | Direct |
| Group II chaperonin (CCT, TRIC), apical domain | 0 | Direct |
| Formate/glycerate dehydrogenases, NAD-domain | 0 | Direct |
| Sterol carrier protein, SCP | 0 | Direct |
| Lamin A/C globular tail domain | 0 | Direct |
| cAMP-binding domain | 0 | Direct |
| Pepsin inhibitor-3 | 0 | Direct |
| ALDH-like | 0 | Direct |
| Anticodon-binding domain of Class II aaRS | 0 | Direct |
| Biotin dependent carboxylase carboxyltransferase domain | 0 | Direct |
| Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | Direct |
| Bacterial exopeptidase dimerisation domain | 0 | Direct |
| Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | Direct |
| Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta | 0 | Direct |
| Pleckstrin-homology domain (PH domain) | 0 | Direct |
| Peptidylglycine alpha-hydroxylating monooxygenase, PHM | 0 | Direct |
| Ribosomal protein S10 | 0 | Direct |
| Cdc48 domain 2-like | 0 | Direct |
| RNA editing terminal uridyl transferase 2, RET2, domain 2 | 0 | Direct |
| PEP carboxykinase C-terminal domain | 0 | Direct |
| Regulator of G-protein signaling, RGS | 0 | Direct |
| DNA repair protein MutS, domain III | 0 | Direct |
| Calcium ATPase, transmembrane domain M | 0 | Direct |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
| VHS domain | 0 | Direct |
| Quinoprotein alcohol dehydrogenase-like | 0 | Direct |
| AN1-like Zinc finger | 0 | Direct |
| BC C-terminal domain-like | 0 | Direct |
| Inositol polyphosphate kinase (IPK) | 0 | Direct |
| PDEase | 0 | Direct |
| beta-Lactamase/D-ala carboxypeptidase | 0 | Direct |
| Amylase, catalytic domain | 0 | Direct |
| Adenosine/AMP deaminase | 0 | Direct |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Troponin I | 0 | Direct |
| Anticodon-binding domain | 0 | Direct |
| LDH N-terminal domain-like | 0 | Direct |
| Tim10/DDP | 0 | Direct |
| Cullin repeat | 0 | Direct |
| LacY-like proton/sugar symporter | 0 | Direct |
| PDI-like | 0 | Direct |
| Alcohol dehydrogenase-like, C-terminal domain | 0 | Direct |
| Sec63 C-terminal domain-like | 0 | Direct |
| WWE domain | 0 | Direct |
| Aquaporin-like | 0 | Direct |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | Direct |
| Sec63 N-terminal domain | 0 | Direct |
| Ngr ectodomain-like | 0 | Direct |
| SMAD domain | 0 | Direct |
| Translational machinery components | 0 | Direct |
| HD domain | 0 | Direct |
| Protein prenyltransferases | 0 | Direct |
| GAPDH-like | 0 | Direct |
| Internalin LRR domain | 0 | Direct |
| Hydantoinase (dihydropyrimidinase) | 0 | Direct |
| Glycosyl transferases group 1 | 0 | Direct |
| ets domain | 0 | Direct |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
| Double-stranded RNA-binding domain (dsRBD) | 0 | Direct |
| DNA gyrase/MutL, second domain | 0 | Direct |
| ValRS/IleRS/LeuRS editing domain | 0 | Direct |
| alpha-catenin/vinculin | 0 | Direct |
| Dimeric isocitrate & isopropylmalate dehydrogenases | 0 | Direct |
| Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains | 0 | Direct |
| Ribokinase-like | 0 | Direct |
| Heat shock protein 90, HSP90, N-terminal domain | 0 | Direct |
| Ubiquitin carboxyl-terminal hydrolase UCH-L | 0 | Direct |
| Small-conductance potassium channel | 0 | Direct |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
| Proteasome subunits | 0 | Direct |
| 5' to 3' exonuclease catalytic domain | 0 | Direct |
| Arylsulfatase | 0 | Direct |
| Clathrin adaptor core protein | 0 | Direct |
| Chromo domain | 0 | Direct |
| Group II chaperonin (CCT, TRIC), ATPase domain | 0 | Direct |
| NHL repeat | 0 | Direct |
| FHA domain | 0 | Direct |
| Calpain large subunit, catalytic domain (domain II) | 0 | Direct |
| Ribosomal protein L18 and S11 | 0 | Direct |
| Intermediate filament protein, coiled coil region | 0 | Direct |
| DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
| L30e/L7ae ribosomal proteins | 0 | Direct |
| Class I glutamine amidotransferases (GAT) | 0 | Direct |
| Ovomucoid domain III-like | 0 | Direct |
| Mitochondrial carrier | 0 | Direct |
| Blood coagulation inhibitor (disintegrin) | 0 | Direct |
| Glycerophosphoryl diester phosphodiesterase | 0 | Direct |
| Hormone receptor domain | 0 | Direct |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | Direct |
| FtsH protease domain-like | 0 | Direct |
| SAM (sterile alpha motif) domain | 0 | Direct |
| SMAD MH1 domain | 0 | Direct |
| XPF/Rad1/Mus81 nuclease | 0 | Direct |
| Actin/HSP70 | 0 | Direct |
| Sir2 family of transcriptional regulators | 0 | Direct |
| Pancreatic carboxypeptidase, activation domain | 0 | Direct |
| Poly(A) polymerase, PAP, C-terminal domain | 0 | Direct |
| CUT domain | 0 | Direct |
| Glycerol kinase | 0 | Direct |
| Armadillo repeat | 0 | Direct |
| Cadherin | 0 | Direct |
| Nucleosome core histones | 0 | Direct |
| Cyclin | 0 | Direct |
| Thyroglobulin type-1 domain | 0 | Direct |
| Skp1 dimerisation domain-like | 0 | Direct |
| L-aminoacid/polyamine oxidase | 0 | Direct |
| Arginine methyltransferase | 0 | Direct |
| Cofilin-like | 0 | Direct |
| WGR domain | 0 | Direct |
| Regulator of chromosome condensation RCC1 | 0 | Direct |
| MIF4G domain-like | 0 | Direct |
| Nop domain | 0 | Direct |
| Branched-chain alpha-keto acid dehydrogenase Pyr module | 0 | Direct |
| Polo-box duplicated region | 0 | Direct |
| acyl-CoA oxidase N-terminal domains | 0 | Direct |
| Single strand DNA-binding domain, SSB | 0 | Direct |
| MFPT repeat | 0 | Direct |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
| AMPK-beta glycogen binding domain-like | 0 | Direct |
| D-aminoacid oxidase-like | 0 | Direct |
| Clc chloride channel | 0 | Direct |
| PEP carboxykinase N-terminal domain | 0 | Direct |
| Subtilases | 0 | Direct |
| Cytoplasmic domain of inward rectifier potassium channel | 0 | Direct |
| Proton glutamate symport protein | 0 | Direct |
| IF2B-like | 0 | Direct |
| Clathrin coat assembly domain | 0 | Direct |
| beta 1,4 galactosyltransferase (b4GalT1) | 0 | Direct |
| 28-residue LRR | 0 | Direct |
| Transducin (heterotrimeric G protein), gamma chain | 0 | Direct |
| BEACH domain | 0 | Direct |
| Hedgehog C-terminal (Hog) autoprocessing domain | 0 | Direct |
| Mammalian PLC | 0 | Direct |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
| CAT-like | 0 | Direct |
| Ribosomal protein L1 | 0 | Direct |
| Fatty acid binding protein-like | 0 | Direct |
| NOL1/NOP2/sun | 0 | Direct |
| Proprotein convertase P-domain | 0 | Direct |
| F1F0 ATP synthase subunit C | 0 | Direct |
| Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain | 0 | Direct |
| MIR domain | 0 | Direct |
| Phosphate binding protein-like | 0 | Direct |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | Direct |
| RNA-polymerase beta-prime | 0 | Direct |
| Oxysterol-binding protein | 0 | Direct |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
| PABC (PABP) domain | 0 | Direct |
| BAR domain | 0 | Direct |
| Tubulin, GTPase domain | 0 | Direct |
| Pancreatic carboxypeptidases | 0 | Direct |
| Integrin domains | 0 | Direct |
| PLC-like (P variant) | 0 | Direct |
| Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | Direct |
| D-aminoacid oxidase, N-terminal domain | 0 | Direct |
| YWTD domain | 0 | Direct |
| Lactate & malate dehydrogenases, C-terminal domain | 0 | Direct |
| Phoshoinositide 3-kinase (PI3K), catalytic domain | 0 | Direct |
| GHMP Kinase, N-terminal domain | 0 | Direct |
| Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain | 0 | Direct |
| ARID domain | 0 | Direct |
| Cullin homology domain | 0 | Direct |
| Translation initiation factor eIF4e | 0 | Direct |
| Hexokinase | 0 | Direct |
| RNA-polymerase beta | 0 | Direct |
| Smc hinge domain | 0 | Direct |
| Crotonase-like | 0 | Direct |
| BC ATP-binding domain-like | 0 | Direct |
| Phosphatidylethanolamine binding protein | 0 | Direct |
| HSP40/DnaJ peptide-binding domain | 0 | Direct |
| MOSC N-terminal domain-like | 0 | Direct |
| Cu,Zn superoxide dismutase-like | 0 | Direct |
| Paired domain | 0 | Direct |
| Pyk2-associated protein beta ARF-GAP domain | 0 | Direct |
| RhoGDI-like | 0 | Direct |
| SWIB/MDM2 domain | 0 | Direct |
| PurM C-terminal domain-like | 0 | Direct |
| Myeloperoxidase-like | 0 | Direct |
| Citrate synthase | 0 | Direct |
| Erythroid transcription factor GATA-1 | 0 | Direct |
| Class I aldolase | 0 | Direct |
| U-box | 0 | Direct |
| Complement control module/SCR domain | 0 | Direct |
| DPP6 catalytic domain-like | 0 | Direct |
| Phosphoglucomutase, first 3 domains | 0 | Direct |
| Zn-finger domain of Sec23/24 | 0 | Direct |
| Ras-binding domain, RBD | 0 | Direct |
| Gamma-glutamyltranspeptidase-like | 0 | Direct |
| COMT-like | 0 | Direct |
| Transducin (alpha subunit), insertion domain | 0 | Direct |
| La domain | 0 | Direct |
| Bactericidal permeability-increasing protein, BPI | 0 | Direct |
| LysM domain | 0 | Direct |
| SWIRM domain | 0 | Direct |
| FAD-dependent thiol oxidase | 0 | Direct |
| Domain of poly(ADP-ribose) polymerase | 0 | Direct |
| ATP-dependent protease Lon (La), catalytic domain | 0 | Direct |
| 14-3-3 protein | 0 | Direct |
| AlkB-like | 0 | Direct |
| Cell cycle control phosphatase, catalytic domain | 0 | Direct |
| Glycogenin | 0 | Direct |
| UBA domain | 0 | Direct |
| Glycolipid transfer protein, GLTP | 0 | Direct |
| p120GAP domain-like | 0 | Direct |
| Medium chain acyl-CoA dehydrogenase-like, C-terminal domain | 0 | Direct |
| Type II chitinase | 0 | Direct |
| Poly(ADP-ribose) polymerase, C-terminal domain | 0 | Direct |
| Type II DNA topoisomerase | 0 | Direct |
| Group II chaperonin (CCT, TRIC), intermediate domain | 0 | Direct |
| GYF domain | 0 | Direct |
| Surp module (SWAP domain) | 0 | Direct |
| acyl-CoA oxidase C-terminal domains | 0 | Direct |
| Elafin-like | 0 | Direct |
| CO dehydrogenase ISP C-domain like | 0 | Direct |
| Poly(A) polymerase, PAP, N-terminal domain | 0 | Direct |
| DEATH domain, DD | 0 | Direct |
| Linker histone H1/H5 | 0 | Direct |
| Acyl-carrier protein (ACP) | 0 | Direct |
| a tRNA synthase domain | 0 | Direct |
| Ferredoxin reductase FAD-binding domain-like | 0 | Direct |
| Hydantoinase (dihydropyrimidinase), catalytic domain | 0 | Direct |
| First domain of FERM | 0 | Direct |
| Phosphotyrosine-binding domain (PTB) | 0 | Direct |
| 1,3-glucuronyltransferase | 0 | Direct |
| LEM domain | 0 | Direct |
| Class II glutamine amidotransferases | 0 | Direct |
| PDZ domain | 0 | Direct |
| PurM N-terminal domain-like | 0 | Direct |
| Tubulin, C-terminal domain | 0 | Direct |
| HCDH C-domain-like | 0 | Direct |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
| Biotinyl/lipoyl-carrier proteins and domains | 0 | Direct |
| S-adenosylmethionine synthetase | 0 | Direct |
| Thiolase-related | 0 | Direct |
| Ubiquitin activating enzymes (UBA) | 0 | Direct |
| Reductases | 0 | Direct |
| PaaI/YdiI-like | 0 | Direct |
| Protein kinases, catalytic subunit | 0.01525 | Inherited |
| WD40-repeat | 0.03027 | Inherited |
| G proteins | 0.0401 | Inherited |
| ABC transporter ATPase domain-like | 0.04592 | Inherited |
| Homeodomain | 0.04622 | Inherited |
| MSP-like | 0.07283 | Inherited |
| L-arabinose binding protein-like | 0.07372 | Inherited |
| SH2 domain | 0.07455 | Inherited |
| Acetyl-CoA synthetase-like | 0.08884 | Inherited |
| CCCH zinc finger | 0.1175 | Inherited |
| Tetratricopeptide repeat (TPR) | 0.1363 | Inherited |
| Cold shock DNA-binding domain-like | 0.1549 | Inherited |
| HLH, helix-loop-helix DNA-binding domain | 0.17 | Inherited |
| Adenylyl and guanylyl cyclase catalytic domain | 0.17 | Inherited |
| Ankyrin repeat | 0.1858 | Inherited |
| Calcium ATPase, transduction domain A | 0.2038 | Inherited |
| Canonical RBD | 0.2092 | Inherited |
| ABC transporter transmembrane region | 0.2256 | Inherited |
| Histone lysine methyltransferases | 0.2437 | Inherited |
| Pepsin-like | 0.2437 | Inherited |
| Class I aminoacyl-tRNA synthetases (RS), catalytic domain | 0.2437 | Inherited |
| DBL homology domain (DH-domain) | 0.2437 | Inherited |
| Extended PAW domain | 0.2437 | Inherited |
| Elongation factors | 0.2437 | Inherited |
| SH3-domain | 0.2533 | Inherited |
| Dual specificity phosphatase-like | 0.2667 | Inherited |
| Acetylcholinesterase-like | 0.2672 | Inherited |
| Metal cation-transporting ATPase, ATP-binding domain N | 0.2912 | Inherited |
| Multidrug efflux transporter AcrB transmembrane domain | 0.3162 | Inherited |
| 6-phosphogluconate dehydrogenase-like, N-terminal domain | 0.3182 | Inherited |
| FYVE, a phosphatidylinositol-3-phosphate binding domain | 0.3182 | Inherited |
| Bromodomain | 0.3182 | Inherited |
| Extended AAA-ATPase domain | 0.3346 | Inherited |
| Cytochrome P450 | 0.3427 | Inherited |
| FAD/NAD-linked reductases, N-terminal and central domains | 0.3476 | Inherited |
| Meta-cation ATPase, catalytic domain P | 0.3795 | Inherited |
| Sm motif of small nuclear ribonucleoproteins, SNRNP | 0.3795 | Inherited |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.4205 | Inherited |
| Pumilio repeat | 0.4499 | Inherited |
| GABA-aminotransferase-like | 0.4499 | Inherited |
| Protein kinase cysteine-rich domain (cys2, phorbol-binding domain) | 0.488 | Inherited |
| Cation efflux protein transmembrane domain-like | 0.4906 | Inherited |
| Nicotinic receptor ligand binding domain-like | 0.4951 | Inherited |
| Glutathione S-transferase (GST), N-terminal domain | 0.506 | Inherited |
| PHD domain | 0.5158 | Inherited |
| t-snare proteins | 0.5344 | Inherited |
| Pyridoxal-dependent decarboxylase | 0.5344 | Inherited |
| Myosin rod fragments | 0.5344 | Inherited |
| I set domains | 0.5776 | Inherited |
| Gastric lipase | 0.58 | Inherited |
| Myb/SANT domain | 0.58 | Inherited |
| Papain-like | 0.5978 | Inherited |
| WW domain | 0.608 | Inherited |
| Class I alpha-1;2-mannosidase, catalytic domain | 0.6302 | Inherited |
| UBC-related | 0.6509 | Inherited |
| Osmotin, thaumatin-like protein | 0.6854 | Inherited |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0.6854 | Inherited |
| Lipovitellin-phosvitin complex, superhelical domain | 0.6854 | Inherited |
| Ubiquitin carboxyl-terminal hydrolase, UCH | 0.7037 | Inherited |
| Synaptotagmin-like (S variant) | 0.7106 | Inherited |
| Growth factor receptor domain | 0.7106 | Inherited |
| BTB/POZ domain | 0.7211 | Inherited |
| EF-hand modules in multidomain proteins | 0.744 | Inherited |
| Transforming growth factor (TGF)-beta | 0.744 | Inherited |
| Voltage-gated potassium channels | 0.779 | Inherited |
| H-NOX domain | 0.806 | Inherited |
| Bacterial lipase | 0.806 | Inherited |
| MIT domain | 0.806 | Inherited |
| Cdc48 N-terminal domain-like | 0.806 | Inherited |
| Ubiquitin-related | 0.8131 | Inherited |
| FAD-linked reductases, N-terminal domain | 0.8501 | Inherited |
| PAZ domain | 0.8768 | Inherited |
| LIM domain | 0.8855 | Inherited |
| Glutathione S-transferase (GST), C-terminal domain | 0.9107 | Inherited |
| Leucine zipper domain | 0.9356 | Inherited |
| Nuclear receptor ligand-binding domain | 0.9483 | Inherited |
| Calmodulin-like | 0.9527 | Inherited |
| DnaQ-like 3'-5' exonuclease | 0.9569 | Inherited |
| NagD-like | 0.9817 | Inherited |
| Ribonuclease PH domain 2-like | 0.9817 | Inherited |
| Ribonuclease PH domain 1-like | 0.9817 | Inherited |
| F-box domain | 1 | Inherited |
| RING finger domain, C3HC4 | 1 | Inherited |
| FKBP immunophilin/proline isomerase | 1 | Inherited |
| N-acetyl transferase, NAT | 1 | Inherited |
| Cyclophilin (peptidylprolyl isomerase) | 1 | Inherited |
| Nuclear receptor | 1 | Inherited |
| B-box zinc-binding domain | 1 | Inherited |
| Choline/Carnitine O-acyltransferase | 1 | Inherited |
| Rhodopsin-like | 1 | Inherited |
| Glutathione peroxidase-like | 1 | Inherited |
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A presence/absence matrix is generated using protein domain
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Supra-domain (including individual superfamily)
(show details)
Supra-domains annotated to this WP term (Not in SPWP)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
| PEP carboxykinase N-terminal domain | 0 | DIRECT |
| Doublecortin (DC) | 0 | DIRECT |
| R3H domain | 0 | DIRECT |
| Calcium-dependent phosphotriesterase | 0 | DIRECT |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | DIRECT |
| eIF4e-like | 0 | DIRECT |
| Integrin domains | 0 | DIRECT |
| Tubby C-terminal domain-like | 0 | DIRECT |
| SAICAR synthase-like | 0 | DIRECT |
| Molybdenum cofactor-binding domain | 0 | DIRECT |
| Nucleotidyltransferase | 0 | DIRECT |
| Ribosomal protein L1 | 0 | DIRECT |
| alpha-catenin/vinculin-like | 0 | DIRECT |
| SIS domain | 0 | DIRECT |
| cAMP-binding domain-like | 0 | DIRECT |
| HSP90 C-terminal domain | 0 | DIRECT |
| VPS9 domain | 0 | DIRECT |
| Phosphoglucomutase, first 3 domains | 0 | DIRECT |
| SCP-like | 0 | DIRECT |
| PreATP-grasp domain | 0 | DIRECT |
| Polo-box domain | 0 | DIRECT |
| Cation efflux protein cytoplasmic domain-like | 0 | DIRECT |
| ALDH-like | 0 | DIRECT |
| Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | DIRECT |
| TK C-terminal domain-like | 0 | DIRECT |
| Profilin (actin-binding protein) | 0 | DIRECT |
| Troponin coil-coiled subunits | 0 | DIRECT |
| CO dehydrogenase ISP C-domain like | 0 | DIRECT |
| PAP/OAS1 substrate-binding domain | 0 | DIRECT |
| ThrRS/AlaRS common domain | 0 | DIRECT |
| Formate/glycerate dehydrogenase catalytic domain-like | 0 | DIRECT |
| Nucleoporin domain | 0 | DIRECT |
| Creatinase/prolidase N-terminal domain | 0 | DIRECT |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
| Band 7/SPFH domain | 0 | DIRECT |
| Kringle-like | 0 | DIRECT |
| CRAL/TRIO N-terminal domain | 0 | DIRECT |
| DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
| L-aspartase-like | 0 | DIRECT |
| Glutathione synthetase ATP-binding domain-like | 0 | DIRECT |
| Ribosomal L27 protein-like | 0 | DIRECT |
| LysM domain | 0 | DIRECT |
| Second domain of FERM | 0 | DIRECT |
| PEBP-like | 0 | DIRECT |
| Surp module (SWAP domain) | 0 | DIRECT |
| Cu,Zn superoxide dismutase-like | 0 | DIRECT |
| Heme-dependent catalase-like | 0 | DIRECT |
| MIR domain | 0 | DIRECT |
| ArfGap/RecO-like zinc finger | 0 | DIRECT |
| Restriction endonuclease-like | 0 | DIRECT |
| S-adenosylmethionine synthetase | 0 | DIRECT |
| TGS-like | 0 | DIRECT |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | DIRECT |
| Outer arm dynein light chain 1 | 0 | DIRECT |
| Phosphoenolpyruvate/pyruvate domain | 0 | DIRECT |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0 | DIRECT |
| Aquaporin-like | 0 | DIRECT |
| Chitinase insertion domain | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
| Invertebrate chitin-binding proteins | 0 | DIRECT |
| Helical domain of Sec23/24 | 0 | DIRECT |
| Sec1/munc18-like (SM) proteins | 0 | DIRECT |
| SWIB/MDM2 domain | 0 | DIRECT |
| DNA repair protein MutS, domain III | 0 | DIRECT |
| Cullin homology domain | 0 | DIRECT |
| Hedgehog/intein (Hint) domain | 0 | DIRECT |
| Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0 | DIRECT |
| Purine and uridine phosphorylases | 0 | DIRECT |
| SPOC domain-like | 0 | DIRECT |
| Sec63 N-terminal domain-like | 0 | DIRECT |
| Transducin (heterotrimeric G protein), gamma chain | 0 | DIRECT |
| Spectrin repeat | 0 | DIRECT |
| CO dehydrogenase molybdoprotein N-domain-like | 0 | DIRECT |
| Acyl-CoA dehydrogenase NM domain-like | 0 | DIRECT |
| PGBD-like | 0 | DIRECT |
| Ran binding protein zinc finger-like | 0 | DIRECT |
| HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
| Pentein | 0 | DIRECT |
| Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
| Ferritin-like | 0 | DIRECT |
| beta-lactamase/transpeptidase-like | 0 | DIRECT |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
| Citrate synthase | 0 | DIRECT |
| Succinyl-CoA synthetase domains | 0 | DIRECT |
| ADP-ribosylation | 0 | DIRECT |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
| Actin-like ATPase domain | 0 | DIRECT |
| Tubulin nucleotide-binding domain-like | 0 | DIRECT |
| GAT-like domain | 0 | DIRECT |
| GroEL apical domain-like | 0 | DIRECT |
| MFPT repeat-like | 0 | DIRECT |
| DNA ligase/mRNA capping enzyme, catalytic domain | 0 | DIRECT |
| Glycolipid transfer protein, GLTP | 0 | DIRECT |
| FtsH protease domain-like | 0 | DIRECT |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | DIRECT |
| Type II DNA topoisomerase | 0 | DIRECT |
| Alpha-L RNA-binding motif | 0 | DIRECT |
| Cdc48 domain 2-like | 0 | DIRECT |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Protease propeptides/inhibitors | 0 | DIRECT |
| PUA domain-like | 0 | DIRECT |
| Thiamin diphosphate-binding fold (THDP-binding) | 0 | DIRECT |
| Heme-dependent peroxidases | 0 | DIRECT |
| Aldolase | 0 | DIRECT |
| RBP11-like subunits of RNA polymerase | 0 | DIRECT |
| Zn-finger domain of Sec23/24 | 0 | DIRECT |
| Skp1 dimerisation domain-like | 0 | DIRECT |
| Terpenoid cyclases/Protein prenyltransferases | 0 | DIRECT |
| Mitochondrial carrier | 0 | DIRECT |
| GroES-like | 0 | DIRECT |
| Single hybrid motif | 0 | DIRECT |
| ValRS/IleRS/LeuRS editing domain | 0 | DIRECT |
| HMG-box | 0 | DIRECT |
| Elafin-like | 0 | DIRECT |
| SMAD MH1 domain | 0 | DIRECT |
| PLC-like phosphodiesterases | 0 | DIRECT |
| FF domain | 0 | DIRECT |
| 3-carboxy-cis,cis-mucoante lactonizing enzyme | 0 | DIRECT |
| WGR domain-like | 0 | DIRECT |
| LEM domain | 0 | DIRECT |
| Tim10-like | 0 | DIRECT |
| Complement control module/SCR domain | 0 | DIRECT |
| Ribosomal protein S10 | 0 | DIRECT |
| L30e-like | 0 | DIRECT |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | DIRECT |
| MgtE membrane domain-like | 0 | DIRECT |
| Subdomain of clathrin and coatomer appendage domain | 0 | DIRECT |
| Proton glutamate symport protein | 0 | DIRECT |
| Domain of poly(ADP-ribose) polymerase | 0 | DIRECT |
| LDH C-terminal domain-like | 0 | DIRECT |
| Oxysterol-binding protein-like | 0 | DIRECT |
| Rap/Ran-GAP | 0 | DIRECT |
| Clc chloride channel | 0 | DIRECT |
| PYP-like sensor domain (PAS domain) | 0 | DIRECT |
| Translational machinery components | 0 | DIRECT |
| Lamin A/C globular tail domain | 0 | DIRECT |
| ISP domain | 0 | DIRECT |
| Diaminopimelate epimerase-like | 0 | DIRECT |
| Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
| Terpenoid synthases | 0 | DIRECT |
| Class I glutamine amidotransferase-like | 0 | DIRECT |
| BEACH domain | 0 | DIRECT |
| Sec7 domain | 0 | DIRECT |
| Activating enzymes of the ubiquitin-like proteins | 0 | DIRECT |
| GYF domain | 0 | DIRECT |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
| Clathrin adaptor appendage domain | 0 | DIRECT |
| Cullin repeat-like | 0 | DIRECT |
| Carbon-nitrogen hydrolase | 0 | DIRECT |
| HCP-like | 0 | DIRECT |
| Hormone receptor domain | 0 | DIRECT |
| ENTH/VHS domain | 0 | DIRECT |
| PurM N-terminal domain-like | 0 | DIRECT |
| Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
| Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | DIRECT |
| PABC (PABP) domain | 0 | DIRECT |
| 2Fe-2S ferredoxin-like | 0 | DIRECT |
| PK beta-barrel domain-like | 0 | DIRECT |
| Bacterial exopeptidase dimerisation domain | 0 | DIRECT |
| FAD-dependent thiol oxidase | 0 | DIRECT |
| PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | DIRECT |
| Nop domain | 0 | DIRECT |
| Ribosomal proteins S24e, L23 and L15e | 0 | DIRECT |
| Insulin-like | 0 | DIRECT |
| PHM/PNGase F | 0 | DIRECT |
| lambda repressor-like DNA-binding domains | 0 | DIRECT |
| Blood coagulation inhibitor (disintegrin) | 0 | DIRECT |
| Carbonic anhydrase | 0 | DIRECT |
| Cystatin/monellin | 0 | DIRECT |
| AN1-like Zinc finger | 0 | DIRECT |
| Carboxypeptidase regulatory domain-like | 0 | DIRECT |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | DIRECT |
| SMAD/FHA domain | 0 | DIRECT |
| Radical SAM enzymes | 0 | DIRECT |
| WWE domain | 0 | DIRECT |
| Acid phosphatase/Vanadium-dependent haloperoxidase | 0 | DIRECT |
| Cytochrome c | 0 | DIRECT |
| Arginase/deacetylase | 0 | DIRECT |
| SAND domain-like | 0 | DIRECT |
| ClpP/crotonase | 0 | DIRECT |
| DEATH domain | 0 | DIRECT |
| Hypothetical protein c14orf129, hspc210 | 0 | DIRECT |
| Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | DIRECT |
| GHMP Kinase, C-terminal domain | 0 | DIRECT |
| Pepsin inhibitor-3 | 0 | DIRECT |
| YWTD domain | 0 | DIRECT |
| Putative DNA-binding domain | 0 | DIRECT |
| HSP20-like chaperones | 0 | DIRECT |
| Smc hinge domain | 0 | DIRECT |
| Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | DIRECT |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
| MOSC N-terminal domain-like | 0 | DIRECT |
| Annexin | 0 | DIRECT |
| Small-conductance potassium channel | 0 | DIRECT |
| CBD9-like | 0 | DIRECT |
| F1F0 ATP synthase subunit C | 0 | DIRECT |
| alpha/beta knot | 0 | DIRECT |
| GroEL equatorial domain-like | 0 | DIRECT |
| Tubulin C-terminal domain-like | 0 | DIRECT |
| GINS helical bundle-like | 0 | DIRECT |
| Isocitrate/Isopropylmalate dehydrogenase-like | 0 | DIRECT |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
| 14-3-3 protein | 0 | DIRECT |
| Thyroglobulin type-1 domain | 0 | DIRECT |
| Transducin (alpha subunit), insertion domain | 0 | DIRECT |
| Ribokinase-like | 0 | DIRECT |
| dsRNA-binding domain-like | 0 | DIRECT |
| Fibrinogen C-terminal domain-like | 0 | DIRECT |
| Chaperone J-domain | 0 | DIRECT |
| GroEL-intermediate domain like | 0 | DIRECT |
| Carbohydrate phosphatase | 0 | DIRECT |
| Zn-binding ribosomal proteins | 0 | DIRECT |
| Intermediate filament protein, coiled coil region | 0 | DIRECT |
| Galactose oxidase, central domain | 0 | DIRECT |
| Nucleoside diphosphate kinase, NDK | 0 | DIRECT |
| ARID-like | 0 | DIRECT |
| JAB1/MPN domain | 0 | DIRECT |
| Lipase/lipooxygenase domain (PLAT/LH2 domain) | 0 | DIRECT |
| GAS2 domain-like | 0 | DIRECT |
| CAD & PB1 domains | 0 | DIRECT |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Subtilisin-like | 0 | DIRECT |
| Chromo domain-like | 0 | DIRECT |
| Aminoacid dehydrogenase-like, N-terminal domain | 0 | DIRECT |
| Ribosomal protein L10-like | 0 | DIRECT |
| Cadherin-like | 0 | DIRECT |
| Hect, E3 ligase catalytic domain | 0 | DIRECT |
| Thiolase-like | 0 | DIRECT |
| YbiA-like | 0 | DIRECT |
| Tricorn protease domain 2 | 0 | DIRECT |
| Rudiment single hybrid motif | 0 | DIRECT |
| Periplasmic binding protein-like II | 0 | DIRECT |
| PurM C-terminal domain-like | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
| PLP-binding barrel | 0 | DIRECT |
| Class II aaRS ABD-related | 0 | DIRECT |
| Integrin alpha N-terminal domain | 0 | DIRECT |
| PEP carboxykinase-like | 0 | DIRECT |
| PIN domain-like | 0 | DIRECT |
| P-loop containing nucleoside triphosphate hydrolases | 0.0000002983 | DIRECT |
| PH domain-like | 0.00005591 | DIRECT |
| Histone-fold | 0.000133 | DIRECT |
| Protein kinase-like (PK-like) | 0.006413 | INHERITED FROM: protein expression variant || organism osmostic stress hypersensitive || anoxia resistant || life span variant || pathogen induced gene expression variant || lipid synthesis increased || protein phosphorylation variant || octanol chemotaxis defective || drug induced gene expression variant || organism environmental stimulus response variant || colchicine resistant || conflicting sensory integration variant || kinase activity reduced || chemotaxis variant || chemical response variant || metal response variant || transgene expression reduced || antimicrobial gene expression variant || dauer induction variant || aldicarb response variant || protein phosphorylation reduced || egg laying response to food variant || alkaline pH chemotaxis variant || protein subcellular localization variant || positive chemotaxis variant |
| PDZ domain-like | 0.01257 | INHERITED FROM: drug response variant || drug resistant || aldicarb response variant || acetylcholinesterase inhibitor response variant |
| Nucleic acid-binding proteins | 0.01819 | INHERITED FROM: mRNA surveillance defective || nonsense mRNA accumulation || sick || hydroxyurea hypersensitive || hydroxyurea response variant || hypoxia resistant |
| Periplasmic binding protein-like I | 0.01902 | INHERITED FROM: memory retention defective || AWC odorant chemotaxis defective || lithium chemotaxis defective || magnesium chemotaxis defective || carbon dioxide avoidance variant || benzaldehyde chemotaxis variant || AWC odorant chemotaxis variant || iodide chemotaxis defective || diacetyl chemotaxis variant || organism environmental stimulus response variant || metabolic pathway variant || second messenger mediated signaling variant || bromide chemotaxis defective || chemotaxis variant || chemical response variant || response to food variant || iodide chemotaxis variant || chemosensory response variant || aqueous positive chemotaxis variant || bromide chemotaxis variant || alkaline pH chemotaxis variant || aqueous chemosensory response variant |
| TPR-like | 0.0201 | INHERITED FROM: light body touch resistant || associative learning variant || dauer defective || chemotaxis variant || osmotic avoidance defective || positive chemotaxis defective |
| "Winged helix" DNA-binding domain | 0.02555 | INHERITED FROM: shortened life span || life span variant || chemical hypersensitive || gene expression variant || organism metabolism processing variant || growth rate variant || spontaneous mutation rate increased || protein aggregation induced behavior variant || protein aggregation variant || protein expression increased || paraquat hypersensitive || anesthetic response variant || germline transgene silencing variant || protein protein interaction variant |
| WD40 repeat-like | 0.02988 | INHERITED FROM: late larval arrest || early larval arrest || organism metabolism processing variant || embryo osmotic integrity defective early emb || osmotic avoidance variant || protein aggregation induced behavior variant || protein aggregation variant || protein protein interaction variant |
| PapD-like | 0.03031 | INHERITED FROM: slow growth || lipid metabolism variant || developmental growth variant || fat content variant || larval arrest || dauer metabolism variant || dauer lifespan extended || larval growth variant || dauer lifespan variant |
| SH2 domain | 0.04544 | INHERITED FROM: protein expression variant || level of protein expression variant || aldicarb resistant || protein expression reduced || acetylcholinesterase inhibitor resistant |
| ARM repeat | 0.06578 | INHERITED FROM: protein expression variant || sick || organism hypersensitive ionizing radiation || gene expression variant || organism metabolism processing variant || RNAi response variant |
| Acetyl-CoA synthetase-like | 0.06697 | INHERITED FROM: lipid metabolism variant |
| Homeodomain-like | 0.072 | INHERITED FROM: carbon dioxide avoidance variant || egg laying imipramine resistant || organism metabolism processing variant || growth rate variant || inhibitor of serotonin uptake variant || carbon dioxide response variant || ectopic expression transgene || adrenergic receptor antagonist response variant || sexually dimorphic physiology variant || imipramine resistant || level of transgene expression variant |
| Cyclin-like | 0.07427 | INHERITED FROM: protein phosphorylation variant || protein phosphorylation reduced |
| EGF/Laminin | 0.08148 | INHERITED FROM: octanol chemotaxis defective || negative chemotaxis variant || odorant negative chemotaxis defective || octanol chemotaxis variant |
| CCCH zinc finger | 0.09138 | INHERITED FROM: transgene expression variant || gene expression variant || mRNA expression ectopic || ectopic expression transgene |
| Translation proteins | 0.1013 | INHERITED FROM: transgene expression variant || sick || gene expression variant || protein phosphorylation variant || organism metabolism processing variant || protein phosphorylation increased || protein aggregation variant || protein protein interaction variant || mRNA levels increased |
| Ankyrin repeat | 0.1068 | INHERITED FROM: octanol chemotaxis defective || organism heat response variant || odorant negative chemotaxis defective || chemotaxis variant || chemosensory response variant || octanol chemotaxis variant |
| Galactose-binding domain-like | 0.1162 | INHERITED FROM: protein interaction variant || protein aggregation variant || protein protein interaction variant |
| Nucleotide cyclase | 0.1261 | INHERITED FROM: AWC odorant chemotaxis defective || lithium chemotaxis defective || magnesium chemotaxis defective || AWC odorant chemotaxis variant || cation positive chemotaxis defective || iodide chemotaxis defective || diacetyl chemotaxis variant || anion positive chemotaxis defective || organism environmental stimulus response variant || metabolic pathway variant || cation positive chemotaxis variant || osmotic avoidance variant || second messenger mediated signaling variant || bromide chemotaxis defective || chemotaxis variant || carbon dioxide response variant || iodide chemotaxis variant || chemosensory response variant || bromide chemotaxis variant || alkaline pH chemotaxis variant || positive chemotaxis variant |
| ABC transporter transmembrane region | 0.1261 | INHERITED FROM: colchicine hypersensitive || organism environmental stimulus response variant || cadmium response variant || metal response variant || RNAi response variant |
| HLH, helix-loop-helix DNA-binding domain | 0.1261 | INHERITED FROM: gene expression level reduced || hypoxia response variant || aqueous positive chemotaxis defective || organism metabolism processing variant || ectopic expression transgene || lysine chemotaxis defective || aqueous positive chemotaxis variant || RNA expression variant |
| Calcium ATPase, transmembrane domain M | 0.1374 | INHERITED FROM: nicotine hypersensitive || drug hypersensitive || organism environmental stimulus response variant || lipid composition variant |
| RNI-like | 0.1417 | INHERITED FROM: resistant to protein aggregation induced paralysis || protein aggregation induced behavior variant |
| Metal cation-transporting ATPase, ATP-binding domain N | 0.1521 | INHERITED FROM: nicotine hypersensitive || drug hypersensitive || organism environmental stimulus response variant || lipid composition variant |
| Regulator of G-protein signaling, RGS | 0.1521 | INHERITED FROM: mechanosensation variant || negative chemotaxis variant || chemotaxis variant |
| Class II aaRS and biotin synthetases | 0.1683 | INHERITED FROM: transgene expression variant || hypoxia response variant || gene expression variant || organism metabolism processing variant || organism environmental stimulus response variant || oxygen response variant || hypoxia resistant |
| Calcium ATPase, transduction domain A | 0.1683 | INHERITED FROM: nicotine hypersensitive || drug hypersensitive || organism environmental stimulus response variant |
| SH3-domain | 0.1794 | INHERITED FROM: protein expression variant || protein phosphorylation variant || protein expression reduced || aldicarb response variant |
| Quinoprotein alcohol dehydrogenase-like | 0.1863 | INHERITED FROM: L2 arrest || hypoxia response variant || mid larval arrest || fat content increased || mRNA levels increased |
| Multidrug efflux transporter AcrB transmembrane domain | 0.2047 | INHERITED FROM: embryo osmotic integrity defective early emb || chemotaxis variant || odorant chemosensory response variant || odorant positive chemotaxis defective || egg integrity defective early emb || positive chemotaxis defective |
| DBL homology domain (DH-domain) | 0.2063 | INHERITED FROM: organism environmental stimulus response variant || pathogen resistance increased || aldicarb response variant || bacterially unswollen || organism pathogen response variant |
| E set domains | 0.2289 | INHERITED FROM: paraquat hypersensitive |
| Cytochrome P450 | 0.2406 | INHERITED FROM: cadmium response variant || metal response variant |
| Multidrug resistance efflux transporter EmrE | 0.2516 | INHERITED FROM: pathogen resistance increased || bacterially unswollen || organism pathogen response variant |
| BRCT domain | 0.2578 | INHERITED FROM: organism ionizing radiation response variant |
| Bromodomain | 0.2775 | INHERITED FROM: sick || ethanol resistant || organism UV hypersensitive || acute functional tolerance to alcohol defective || drug adaptation variant || organism UV response variant || anesthetic response variant || anesthetic resistant |
| 6-phosphogluconate dehydrogenase C-terminal domain-like | 0.2775 | INHERITED FROM: lipid metabolism variant || fat content variant |
| Nucleotidylyl transferase | 0.2989 | INHERITED FROM: mRNA surveillance defective || transgene expression increased || paraquat resistant || hypoxia response variant || organism metabolism processing variant || organism environmental stimulus response variant || oxygen response variant || hypoxia resistant |
| Cysteine proteinases | 0.2997 | INHERITED FROM: protein interaction variant || organism metabolism processing variant || pattern of transgene expression variant || osmotic integrity variant || paraquat hypersensitive || hypoosmotic shock hypersensitive || protein protein interaction variant |
| SNARE-like | 0.3062 | INHERITED FROM: transgene expression variant || aldicarb resistant || sick || gene expression variant || organism metabolism processing variant || transgene subcellular localization variant || pattern of transgene expression variant || aldicarb response variant || acetylcholinesterase inhibitor resistant || acetylcholinesterase inhibitor response variant |
| POZ domain | 0.3077 | INHERITED FROM: L1 arrest || early larval arrest || resistant to protein aggregation induced paralysis || chemical hypersensitive || protein aggregation induced behavior variant |
| Ribosomal protein S5 domain 2-like | 0.3154 | INHERITED FROM: transgene expression variant || early larval arrest |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0.3211 | INHERITED FROM: protein expression variant || nose touch variant || drug induced gene expression variant || organism environmental stimulus response variant || growth rate variant || drug resistant || chemical response variant || antimicrobial gene expression variant || aging variant || innate immune response variant || RNAi response variant || protein subcellular localization variant || organism pathogen response variant |
| SAM/Pointed domain | 0.3212 | INHERITED FROM: hypoxia response variant || aldicarb response variant |
| Lipocalins | 0.3215 | INHERITED FROM: lipid metabolism variant || life span variant || fat content variant || paraquat response variant || fat content increased || paraquat hypersensitive |
| UDP-Glycosyltransferase/glycogen phosphorylase | 0.3313 | INHERITED FROM: organism osmotic stress response variant |
| Nicotinic receptor ligand binding domain-like | 0.3703 | INHERITED FROM: antihelmintic response variant || drug response variant || mechanosensation variant || nicotine resistant || organism environmental stimulus response variant || cholinergic agonist resistant || sodium chloride chemotaxis variant || chemical response variant || DMPP response variant || hypoosmotic shock hypersensitive || selenium response variant || aqueous chemosensory response variant |
| Translation proteins SH3-like domain | 0.3718 | INHERITED FROM: transgene expression variant || early larval arrest || gene expression variant || organism metabolism processing variant || protein aggregation variant || protein protein interaction variant |
| Cation efflux protein transmembrane domain-like | 0.3718 | INHERITED FROM: cadmium hypersensitive || cadmium response variant || metal response variant |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.3935 | INHERITED FROM: antihelmintic response variant || drug response variant || mechanosensation variant || nicotine resistant || organism environmental stimulus response variant || cholinergic agonist resistant || sodium chloride chemotaxis variant || chemical response variant || DMPP response variant || hypoosmotic shock hypersensitive || selenium response variant || positive chemotaxis variant || aqueous chemosensory response variant |
| Acid proteases | 0.3975 | INHERITED FROM: protein interaction variant || transgene expression variant || gene expression variant || organism metabolism processing variant || transgene subcellular localization variant || protein aggregation variant || pattern of transgene expression variant || osmotic integrity variant || hypoosmotic shock hypersensitive || protein protein interaction variant |
| Tropomyosin | 0.4092 | INHERITED FROM: drug resistant |
| Cysteine-rich domain | 0.4217 | INHERITED FROM: protein expression variant || organism oxidative stress resistant || organism metabolism processing variant || drug induced gene expression variant || odorant chemosensory response variant || antimicrobial gene expression variant || odorant positive chemotaxis variant || aldicarb response variant || bacterially unswollen || innate immune response variant || protein subcellular localization variant || positive chemotaxis variant || organism pathogen response variant |
| FYVE/PHD zinc finger | 0.4242 | INHERITED FROM: protein methylation variant || organism UV hypersensitive || protein modification variant || ectopic expression transgene || organism UV response variant |
| Ubiquitin-like | 0.4497 | INHERITED FROM: protein interaction variant || organism metabolism processing variant || protein aggregation variant || protein protein interaction variant |
| RNA-binding domain, RBD | 0.4565 | INHERITED FROM: maintenance of gene silencing variant || sick || RNA processing variant || organism metabolism processing variant || starvation induced apoptosis variant || mRNA export variant || RNA expression variant |
| HAD-like | 0.4836 | INHERITED FROM: nicotine hypersensitive || transgene subcellular localization variant || lipid composition variant |
| PRTase-like | 0.4947 | INHERITED FROM: Fluorouracil resistant || drug resistant |
| Myosin rod fragments | 0.4947 | INHERITED FROM: drug resistant |
| DHS-like NAD/FAD-binding domain | 0.4947 | INHERITED FROM: protein expression variant || life span variant || protein modification variant || protein acetylation variant |
| t-snare proteins | 0.4947 | INHERITED FROM: drug hypersensitive |
| Voltage-gated potassium channels | 0.5284 | INHERITED FROM: mechanosensation variant || growth rate variant || adrenergic receptor antagonist response variant || serotonin response variant || positive chemotaxis defective |
| Ferredoxin reductase-like, C-terminal NADP-linked domain | 0.5416 | INHERITED FROM: pattern protein expression variant |
| Riboflavin synthase domain-like | 0.5416 | INHERITED FROM: pattern protein expression variant |
| Sm-like ribonucleoproteins | 0.5501 | INHERITED FROM: shortened life span || transgene expression variant || sick || gene expression variant || organism heat response variant || pattern of transgene expression variant || protein subcellular localization variant |
| FAD-linked reductases, C-terminal domain | 0.5501 | INHERITED FROM: life span variant |
| WW domain | 0.5501 | INHERITED FROM: maintenance of gene silencing variant || aldicarb resistant || acetylcholinesterase inhibitor resistant |
| Cystine-knot cytokines | 0.5501 | INHERITED FROM: nicotine response variant || levamisole response variant |
| FAD/NAD(P)-binding domain | 0.5868 | INHERITED FROM: life span variant || pesticide response variant |
| Seven-hairpin glycosidases | 0.5931 | INHERITED FROM: extended life span || protein aggregation variant || protein protein interaction variant |
| SET domain | 0.5936 | INHERITED FROM: protein expression variant || protein methylation variant || maintenance of gene silencing variant || shortened life span || histone methylation variant || life span variant || ectopic expression antibody || somatic transgene silencing variant || spontaneous mutation rate increased || protein modification variant || ectopic expression transgene || RNAi response variant || dosage compensation variant |
| UBC-like | 0.6175 | INHERITED FROM: protein interaction variant || late larval arrest || sick || gene expression variant || organism metabolism processing variant || transgene subcellular localization variant || protein aggregation variant || pattern of transgene expression variant || protein protein interaction variant |
| MFS general substrate transporter | 0.6287 | INHERITED FROM: organism high sodium chloride hypersensitive |
| Clavaminate synthase-like | 0.6327 | INHERITED FROM: life span variant || organism temperature response variant |
| Osmotin, thaumatin-like protein | 0.65 | INHERITED FROM: cadmium hypersensitive || cadmium response variant || metal response variant || transgene expression reduced |
| Nucleotide-binding domain | 0.65 | INHERITED FROM: life span variant || extended life span |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0.65 | INHERITED FROM: life span variant || transgene subcellular localization variant || organism environmental stimulus response variant || pathogen susceptibility increased || organism pathogen response variant |
| Lipovitellin-phosvitin complex, superhelical domain | 0.65 | INHERITED FROM: life span variant || transgene subcellular localization variant || organism environmental stimulus response variant || pathogen susceptibility increased || organism pathogen response variant |
| KA1-like | 0.65 | INHERITED FROM: RNA expression variant |
| Rhodanese/Cell cycle control phosphatase | 0.6558 | INHERITED FROM: pathogen susceptibility increased |
| S15/NS1 RNA-binding domain | 0.7131 | INHERITED FROM: transgene expression increased |
| Glucocorticoid receptor-like (DNA-binding domain) | 0.7512 | INHERITED FROM: gene expression level reduced || dauer resistance to harsh conditions variant || SDS sensitive dauer || fat content increased || transgene expression reduced || gene expression level high || level of transgene expression variant |
| GST C-terminal domain-like | 0.7544 | INHERITED FROM: organism electrophilic stress hypersensitive || organism stress response variant || enzyme activity variant || organism environmental stimulus response variant || organism heat hypersensitive || cadmium hypersensitive || cadmium response variant || enzyme activity reduced |
| Ribonuclease H-like | 0.7653 | INHERITED FROM: maintenance of gene silencing variant || siRNA expression variant || somatic transgene silencing variant || RNAi enhanced || 21U RNA expression variant || RNAi response variant || RNA expression variant |
| alpha/beta-Hydrolases | 0.7656 | INHERITED FROM: enzyme activity reduced || acetylcholinesterase activity variant || acetylcholinesterase reduced |
| PAZ domain | 0.7689 | INHERITED FROM: maintenance of gene silencing variant || siRNA expression variant || somatic transgene silencing variant || RNAi enhanced || 21U RNA expression variant || RNAi response variant || mRNA levels increased || RNA expression variant |
| MIT domain | 0.7811 | INHERITED FROM: protein interaction variant || protein aggregation variant || protein protein interaction variant |
| ADC-like | 0.7811 | INHERITED FROM: protein interaction variant || protein aggregation variant || level of transgene expression variant || protein protein interaction variant |
| Fibronectin type III | 0.8334 | INHERITED FROM: growth rate variant || organism temperature response variant |
| UBA-like | 0.8879 | INHERITED FROM: protein aggregation variant || protein protein interaction variant |
| Leucine zipper domain | 0.8905 | INHERITED FROM: organism environmental stimulus response variant || mRNA expression variant || transgene expression reduced || pore forming toxin response variant || mRNA levels reduced || organism pathogen response variant || level of transgene expression variant |
| GTPase activation domain, GAP | 0.9026 | INHERITED FROM: protein expression variant |
| EF-hand | 0.9085 | INHERITED FROM: protein interaction variant || protein aggregation variant |
| p53-like transcription factors | 0.9566 | INHERITED FROM: gene expression level reduced || ectopic expression transgene || level of transgene expression variant |
| Ribonuclease PH domain 2-like | 0.9627 | INHERITED FROM: early larval arrest |
| Immunoglobulin | 0.9889 | INHERITED FROM: growth rate variant || aldicarb response variant |
| beta-beta-alpha zinc fingers | 0.9935 | INHERITED FROM: egg laying serotonin resistant || egg laying imipramine resistant || organism metabolism processing variant || inhibitor of serotonin uptake variant || imipramine resistant |
| Family A G protein-coupled receptor-like | 1 | INHERITED FROM: locomotion rate serotonin variant || serotonin induced fat reduction variant || male tail curling serotonin variant || serotonin induced pumping variant |
| Bet v1-like | 1 | INHERITED FROM: growth rate variant |
| Eukaryotic type KH-domain (KH-domain type I) | 1 | INHERITED FROM: RNA expression variant |
| FKBP-like | 1 | INHERITED FROM: protein interaction variant || transgene subcellular localization variant || protein aggregation variant || pattern of transgene expression variant || protein protein interaction variant |
| Cyclophilin-like | 1 | INHERITED FROM: protein interaction variant || transgene expression variant || gene expression variant || organism metabolism processing variant || transgene subcellular localization variant || protein aggregation variant || pattern of transgene expression variant || protein protein interaction variant |
| Nuclear receptor ligand-binding domain | 1 | INHERITED FROM: gene expression level reduced || lipid metabolism variant || chemical hypersensitive || dauer resistance to harsh conditions variant || SDS sensitive dauer || fat content increased || transgene expression reduced || gene expression level high || level of transgene expression variant |
| RING/U-box | 1 | INHERITED FROM: protein interaction variant || transgene expression variant || gene expression variant || organism metabolism processing variant || transgene subcellular localization variant || protein aggregation variant || pattern of transgene expression variant || protein protein interaction variant |
| Saposin | 1 | INHERITED FROM: transgene expression variant || increased pathogen survival || transgene expression reduced || pathogen load variant || organism pathogen response variant || level of transgene expression variant |
| CoA-dependent acyltransferases | 1 | INHERITED FROM: fat content variant |
| F-box domain | 1 | INHERITED FROM: resistant to protein aggregation induced paralysis |
| Ligand-binding domain in the NO signalling and Golgi transport | 1 | INHERITED FROM: carbon dioxide avoidance variant || carbon dioxide response variant |
| Thioredoxin-like | 1 | INHERITED FROM: organism electrophilic stress hypersensitive || organism stress response variant || enzyme activity variant || paraquat response variant || organism environmental stimulus response variant || organism heat hypersensitive || cadmium hypersensitive || enzyme activity reduced || pesticide response variant |
| B-box zinc-binding domain | 1 | INHERITED FROM: protein interaction variant || transgene expression variant || gene expression variant || organism metabolism processing variant || transgene subcellular localization variant || protein aggregation variant || protein protein interaction variant |
| Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
| PEP carboxykinase N-terminal domain | 0 | Direct |
| Doublecortin (DC) | 0 | Direct |
| R3H domain | 0 | Direct |
| Calcium-dependent phosphotriesterase | 0 | Direct |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | Direct |
| eIF4e-like | 0 | Direct |
| Integrin domains | 0 | Direct |
| Tubby C-terminal domain-like | 0 | Direct |
| SAICAR synthase-like | 0 | Direct |
| Molybdenum cofactor-binding domain | 0 | Direct |
| Nucleotidyltransferase | 0 | Direct |
| Ribosomal protein L1 | 0 | Direct |
| alpha-catenin/vinculin-like | 0 | Direct |
| SIS domain | 0 | Direct |
| cAMP-binding domain-like | 0 | Direct |
| HSP90 C-terminal domain | 0 | Direct |
| VPS9 domain | 0 | Direct |
| Phosphoglucomutase, first 3 domains | 0 | Direct |
| SCP-like | 0 | Direct |
| PreATP-grasp domain | 0 | Direct |
| Polo-box domain | 0 | Direct |
| Cation efflux protein cytoplasmic domain-like | 0 | Direct |
| ALDH-like | 0 | Direct |
| Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | Direct |
| TK C-terminal domain-like | 0 | Direct |
| Profilin (actin-binding protein) | 0 | Direct |
| Troponin coil-coiled subunits | 0 | Direct |
| CO dehydrogenase ISP C-domain like | 0 | Direct |
| PAP/OAS1 substrate-binding domain | 0 | Direct |
| ThrRS/AlaRS common domain | 0 | Direct |
| Formate/glycerate dehydrogenase catalytic domain-like | 0 | Direct |
| Nucleoporin domain | 0 | Direct |
| Creatinase/prolidase N-terminal domain | 0 | Direct |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
| Band 7/SPFH domain | 0 | Direct |
| Kringle-like | 0 | Direct |
| CRAL/TRIO N-terminal domain | 0 | Direct |
| DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
| L-aspartase-like | 0 | Direct |
| Glutathione synthetase ATP-binding domain-like | 0 | Direct |
| Ribosomal L27 protein-like | 0 | Direct |
| LysM domain | 0 | Direct |
| Second domain of FERM | 0 | Direct |
| PEBP-like | 0 | Direct |
| Surp module (SWAP domain) | 0 | Direct |
| Cu,Zn superoxide dismutase-like | 0 | Direct |
| Heme-dependent catalase-like | 0 | Direct |
| MIR domain | 0 | Direct |
| ArfGap/RecO-like zinc finger | 0 | Direct |
| Restriction endonuclease-like | 0 | Direct |
| S-adenosylmethionine synthetase | 0 | Direct |
| TGS-like | 0 | Direct |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | Direct |
| Outer arm dynein light chain 1 | 0 | Direct |
| Phosphoenolpyruvate/pyruvate domain | 0 | Direct |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0 | Direct |
| Aquaporin-like | 0 | Direct |
| Chitinase insertion domain | 0 | Direct |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
| Invertebrate chitin-binding proteins | 0 | Direct |
| Helical domain of Sec23/24 | 0 | Direct |
| Sec1/munc18-like (SM) proteins | 0 | Direct |
| SWIB/MDM2 domain | 0 | Direct |
| DNA repair protein MutS, domain III | 0 | Direct |
| Cullin homology domain | 0 | Direct |
| Hedgehog/intein (Hint) domain | 0 | Direct |
| Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0 | Direct |
| Purine and uridine phosphorylases | 0 | Direct |
| SPOC domain-like | 0 | Direct |
| Sec63 N-terminal domain-like | 0 | Direct |
| Transducin (heterotrimeric G protein), gamma chain | 0 | Direct |
| Spectrin repeat | 0 | Direct |
| CO dehydrogenase molybdoprotein N-domain-like | 0 | Direct |
| Acyl-CoA dehydrogenase NM domain-like | 0 | Direct |
| PGBD-like | 0 | Direct |
| Ran binding protein zinc finger-like | 0 | Direct |
| HSP40/DnaJ peptide-binding domain | 0 | Direct |
| Pentein | 0 | Direct |
| Composite domain of metallo-dependent hydrolases | 0 | Direct |
| Ferritin-like | 0 | Direct |
| beta-lactamase/transpeptidase-like | 0 | Direct |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
| Citrate synthase | 0 | Direct |
| Succinyl-CoA synthetase domains | 0 | Direct |
| ADP-ribosylation | 0 | Direct |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
| Actin-like ATPase domain | 0 | Direct |
| Tubulin nucleotide-binding domain-like | 0 | Direct |
| GAT-like domain | 0 | Direct |
| GroEL apical domain-like | 0 | Direct |
| MFPT repeat-like | 0 | Direct |
| DNA ligase/mRNA capping enzyme, catalytic domain | 0 | Direct |
| Glycolipid transfer protein, GLTP | 0 | Direct |
| FtsH protease domain-like | 0 | Direct |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | Direct |
| Type II DNA topoisomerase | 0 | Direct |
| Alpha-L RNA-binding motif | 0 | Direct |
| Cdc48 domain 2-like | 0 | Direct |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Protease propeptides/inhibitors | 0 | Direct |
| PUA domain-like | 0 | Direct |
| Thiamin diphosphate-binding fold (THDP-binding) | 0 | Direct |
| Heme-dependent peroxidases | 0 | Direct |
| Aldolase | 0 | Direct |
| RBP11-like subunits of RNA polymerase | 0 | Direct |
| Zn-finger domain of Sec23/24 | 0 | Direct |
| Skp1 dimerisation domain-like | 0 | Direct |
| Terpenoid cyclases/Protein prenyltransferases | 0 | Direct |
| Mitochondrial carrier | 0 | Direct |
| GroES-like | 0 | Direct |
| Single hybrid motif | 0 | Direct |
| ValRS/IleRS/LeuRS editing domain | 0 | Direct |
| HMG-box | 0 | Direct |
| Elafin-like | 0 | Direct |
| SMAD MH1 domain | 0 | Direct |
| PLC-like phosphodiesterases | 0 | Direct |
| FF domain | 0 | Direct |
| 3-carboxy-cis,cis-mucoante lactonizing enzyme | 0 | Direct |
| WGR domain-like | 0 | Direct |
| LEM domain | 0 | Direct |
| Tim10-like | 0 | Direct |
| Complement control module/SCR domain | 0 | Direct |
| Ribosomal protein S10 | 0 | Direct |
| L30e-like | 0 | Direct |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | Direct |
| MgtE membrane domain-like | 0 | Direct |
| Subdomain of clathrin and coatomer appendage domain | 0 | Direct |
| Proton glutamate symport protein | 0 | Direct |
| Domain of poly(ADP-ribose) polymerase | 0 | Direct |
| LDH C-terminal domain-like | 0 | Direct |
| Oxysterol-binding protein-like | 0 | Direct |
| Rap/Ran-GAP | 0 | Direct |
| Clc chloride channel | 0 | Direct |
| PYP-like sensor domain (PAS domain) | 0 | Direct |
| Translational machinery components | 0 | Direct |
| Lamin A/C globular tail domain | 0 | Direct |
| ISP domain | 0 | Direct |
| Diaminopimelate epimerase-like | 0 | Direct |
| Phosphoglucomutase, C-terminal domain | 0 | Direct |
| Terpenoid synthases | 0 | Direct |
| Class I glutamine amidotransferase-like | 0 | Direct |
| BEACH domain | 0 | Direct |
| Sec7 domain | 0 | Direct |
| Activating enzymes of the ubiquitin-like proteins | 0 | Direct |
| GYF domain | 0 | Direct |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
| Clathrin adaptor appendage domain | 0 | Direct |
| Cullin repeat-like | 0 | Direct |
| Carbon-nitrogen hydrolase | 0 | Direct |
| HCP-like | 0 | Direct |
| Hormone receptor domain | 0 | Direct |
| ENTH/VHS domain | 0 | Direct |
| PurM N-terminal domain-like | 0 | Direct |
| Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
| Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | Direct |
| PABC (PABP) domain | 0 | Direct |
| 2Fe-2S ferredoxin-like | 0 | Direct |
| PK beta-barrel domain-like | 0 | Direct |
| Bacterial exopeptidase dimerisation domain | 0 | Direct |
| FAD-dependent thiol oxidase | 0 | Direct |
| PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | Direct |
| Nop domain | 0 | Direct |
| Ribosomal proteins S24e, L23 and L15e | 0 | Direct |
| Insulin-like | 0 | Direct |
| PHM/PNGase F | 0 | Direct |
| lambda repressor-like DNA-binding domains | 0 | Direct |
| Blood coagulation inhibitor (disintegrin) | 0 | Direct |
| Carbonic anhydrase | 0 | Direct |
| Cystatin/monellin | 0 | Direct |
| AN1-like Zinc finger | 0 | Direct |
| Carboxypeptidase regulatory domain-like | 0 | Direct |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | Direct |
| SMAD/FHA domain | 0 | Direct |
| Radical SAM enzymes | 0 | Direct |
| WWE domain | 0 | Direct |
| Acid phosphatase/Vanadium-dependent haloperoxidase | 0 | Direct |
| Cytochrome c | 0 | Direct |
| Arginase/deacetylase | 0 | Direct |
| SAND domain-like | 0 | Direct |
| ClpP/crotonase | 0 | Direct |
| DEATH domain | 0 | Direct |
| Hypothetical protein c14orf129, hspc210 | 0 | Direct |
| Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | Direct |
| GHMP Kinase, C-terminal domain | 0 | Direct |
| Pepsin inhibitor-3 | 0 | Direct |
| YWTD domain | 0 | Direct |
| Putative DNA-binding domain | 0 | Direct |
| HSP20-like chaperones | 0 | Direct |
| Smc hinge domain | 0 | Direct |
| Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | Direct |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
| MOSC N-terminal domain-like | 0 | Direct |
| Annexin | 0 | Direct |
| Small-conductance potassium channel | 0 | Direct |
| CBD9-like | 0 | Direct |
| F1F0 ATP synthase subunit C | 0 | Direct |
| alpha/beta knot | 0 | Direct |
| GroEL equatorial domain-like | 0 | Direct |
| Tubulin C-terminal domain-like | 0 | Direct |
| GINS helical bundle-like | 0 | Direct |
| Isocitrate/Isopropylmalate dehydrogenase-like | 0 | Direct |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | Direct |
| 14-3-3 protein | 0 | Direct |
| Thyroglobulin type-1 domain | 0 | Direct |
| Transducin (alpha subunit), insertion domain | 0 | Direct |
| Ribokinase-like | 0 | Direct |
| dsRNA-binding domain-like | 0 | Direct |
| Fibrinogen C-terminal domain-like | 0 | Direct |
| Chaperone J-domain | 0 | Direct |
| GroEL-intermediate domain like | 0 | Direct |
| Carbohydrate phosphatase | 0 | Direct |
| Zn-binding ribosomal proteins | 0 | Direct |
| Intermediate filament protein, coiled coil region | 0 | Direct |
| Galactose oxidase, central domain | 0 | Direct |
| Nucleoside diphosphate kinase, NDK | 0 | Direct |
| ARID-like | 0 | Direct |
| JAB1/MPN domain | 0 | Direct |
| Lipase/lipooxygenase domain (PLAT/LH2 domain) | 0 | Direct |
| GAS2 domain-like | 0 | Direct |
| CAD & PB1 domains | 0 | Direct |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Subtilisin-like | 0 | Direct |
| Chromo domain-like | 0 | Direct |
| Aminoacid dehydrogenase-like, N-terminal domain | 0 | Direct |
| Ribosomal protein L10-like | 0 | Direct |
| Cadherin-like | 0 | Direct |
| Hect, E3 ligase catalytic domain | 0 | Direct |
| Thiolase-like | 0 | Direct |
| YbiA-like | 0 | Direct |
| Tricorn protease domain 2 | 0 | Direct |
| Rudiment single hybrid motif | 0 | Direct |
| Periplasmic binding protein-like II | 0 | Direct |
| PurM C-terminal domain-like | 0 | Direct |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
| PLP-binding barrel | 0 | Direct |
| Class II aaRS ABD-related | 0 | Direct |
| Integrin alpha N-terminal domain | 0 | Direct |
| PEP carboxykinase-like | 0 | Direct |
| PIN domain-like | 0 | Direct |
| P-loop containing nucleoside triphosphate hydrolases | 0.0000002983 | Direct |
| PH domain-like | 0.00005591 | Direct |
| Histone-fold | 0.000133 | Direct |
| Protein kinase-like (PK-like) | 0.006413 | Inherited |
| PDZ domain-like | 0.01257 | Inherited |
| Nucleic acid-binding proteins | 0.01819 | Inherited |
| Periplasmic binding protein-like I | 0.01902 | Inherited |
| TPR-like | 0.0201 | Inherited |
| "Winged helix" DNA-binding domain | 0.02555 | Inherited |
| WD40 repeat-like | 0.02988 | Inherited |
| PapD-like | 0.03031 | Inherited |
| SH2 domain | 0.04544 | Inherited |
| ARM repeat | 0.06578 | Inherited |
| Acetyl-CoA synthetase-like | 0.06697 | Inherited |
| Homeodomain-like | 0.072 | Inherited |
| Cyclin-like | 0.07427 | Inherited |
| EGF/Laminin | 0.08148 | Inherited |
| CCCH zinc finger | 0.09138 | Inherited |
| Translation proteins | 0.1013 | Inherited |
| Ankyrin repeat | 0.1068 | Inherited |
| Galactose-binding domain-like | 0.1162 | Inherited |
| Nucleotide cyclase | 0.1261 | Inherited |
| ABC transporter transmembrane region | 0.1261 | Inherited |
| HLH, helix-loop-helix DNA-binding domain | 0.1261 | Inherited |
| Calcium ATPase, transmembrane domain M | 0.1374 | Inherited |
| RNI-like | 0.1417 | Inherited |
| Metal cation-transporting ATPase, ATP-binding domain N | 0.1521 | Inherited |
| Regulator of G-protein signaling, RGS | 0.1521 | Inherited |
| Class II aaRS and biotin synthetases | 0.1683 | Inherited |
| Calcium ATPase, transduction domain A | 0.1683 | Inherited |
| SH3-domain | 0.1794 | Inherited |
| Quinoprotein alcohol dehydrogenase-like | 0.1863 | Inherited |
| Multidrug efflux transporter AcrB transmembrane domain | 0.2047 | Inherited |
| DBL homology domain (DH-domain) | 0.2063 | Inherited |
| E set domains | 0.2289 | Inherited |
| Cytochrome P450 | 0.2406 | Inherited |
| Multidrug resistance efflux transporter EmrE | 0.2516 | Inherited |
| BRCT domain | 0.2578 | Inherited |
| Bromodomain | 0.2775 | Inherited |
| 6-phosphogluconate dehydrogenase C-terminal domain-like | 0.2775 | Inherited |
| Nucleotidylyl transferase | 0.2989 | Inherited |
| Cysteine proteinases | 0.2997 | Inherited |
| SNARE-like | 0.3062 | Inherited |
| POZ domain | 0.3077 | Inherited |
| Ribosomal protein S5 domain 2-like | 0.3154 | Inherited |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0.3211 | Inherited |
| SAM/Pointed domain | 0.3212 | Inherited |
| Lipocalins | 0.3215 | Inherited |
| UDP-Glycosyltransferase/glycogen phosphorylase | 0.3313 | Inherited |
| Nicotinic receptor ligand binding domain-like | 0.3703 | Inherited |
| Translation proteins SH3-like domain | 0.3718 | Inherited |
| Cation efflux protein transmembrane domain-like | 0.3718 | Inherited |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.3935 | Inherited |
| Acid proteases | 0.3975 | Inherited |
| Tropomyosin | 0.4092 | Inherited |
| Cysteine-rich domain | 0.4217 | Inherited |
| FYVE/PHD zinc finger | 0.4242 | Inherited |
| Ubiquitin-like | 0.4497 | Inherited |
| RNA-binding domain, RBD | 0.4565 | Inherited |
| HAD-like | 0.4836 | Inherited |
| PRTase-like | 0.4947 | Inherited |
| Myosin rod fragments | 0.4947 | Inherited |
| DHS-like NAD/FAD-binding domain | 0.4947 | Inherited |
| t-snare proteins | 0.4947 | Inherited |
| Voltage-gated potassium channels | 0.5284 | Inherited |
| Ferredoxin reductase-like, C-terminal NADP-linked domain | 0.5416 | Inherited |
| Riboflavin synthase domain-like | 0.5416 | Inherited |
| Sm-like ribonucleoproteins | 0.5501 | Inherited |
| FAD-linked reductases, C-terminal domain | 0.5501 | Inherited |
| WW domain | 0.5501 | Inherited |
| Cystine-knot cytokines | 0.5501 | Inherited |
| FAD/NAD(P)-binding domain | 0.5868 | Inherited |
| Seven-hairpin glycosidases | 0.5931 | Inherited |
| SET domain | 0.5936 | Inherited |
| UBC-like | 0.6175 | Inherited |
| MFS general substrate transporter | 0.6287 | Inherited |
| Clavaminate synthase-like | 0.6327 | Inherited |
| Osmotin, thaumatin-like protein | 0.65 | Inherited |
| Nucleotide-binding domain | 0.65 | Inherited |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0.65 | Inherited |
| Lipovitellin-phosvitin complex, superhelical domain | 0.65 | Inherited |
| KA1-like | 0.65 | Inherited |
| Rhodanese/Cell cycle control phosphatase | 0.6558 | Inherited |
| S15/NS1 RNA-binding domain | 0.7131 | Inherited |
| Glucocorticoid receptor-like (DNA-binding domain) | 0.7512 | Inherited |
| GST C-terminal domain-like | 0.7544 | Inherited |
| Ribonuclease H-like | 0.7653 | Inherited |
| alpha/beta-Hydrolases | 0.7656 | Inherited |
| PAZ domain | 0.7689 | Inherited |
| MIT domain | 0.7811 | Inherited |
| ADC-like | 0.7811 | Inherited |
| Fibronectin type III | 0.8334 | Inherited |
| UBA-like | 0.8879 | Inherited |
| Leucine zipper domain | 0.8905 | Inherited |
| GTPase activation domain, GAP | 0.9026 | Inherited |
| EF-hand | 0.9085 | Inherited |
| p53-like transcription factors | 0.9566 | Inherited |
| Ribonuclease PH domain 2-like | 0.9627 | Inherited |
| Immunoglobulin | 0.9889 | Inherited |
| beta-beta-alpha zinc fingers | 0.9935 | Inherited |
| Family A G protein-coupled receptor-like | 1 | Inherited |
| Bet v1-like | 1 | Inherited |
| Eukaryotic type KH-domain (KH-domain type I) | 1 | Inherited |
| FKBP-like | 1 | Inherited |
| Cyclophilin-like | 1 | Inherited |
| Nuclear receptor ligand-binding domain | 1 | Inherited |
| RING/U-box | 1 | Inherited |
| Saposin | 1 | Inherited |
| CoA-dependent acyltransferases | 1 | Inherited |
| F-box domain | 1 | Inherited |
| Ligand-binding domain in the NO signalling and Golgi transport | 1 | Inherited |
| Thioredoxin-like | 1 | Inherited |
| B-box zinc-binding domain | 1 | Inherited |
(show details)
Supra-domains annotated to this WP term (Not in SPWP)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
51338,51556
51338 - Composite domain of metallo-dependent hydrolases
51556 - Metallo-dependent hydrolases | 0 | DIRECT |
57362,57362
57362 - BPTI-like
57362 - BPTI-like | 0 | DIRECT |
52113,52113
52113 - BRCT domain
52113 - BRCT domain | 0 | DIRECT |
47473,51695
47473 - EF-hand
51695 - PLC-like phosphodiesterases | 0 | DIRECT |
48464,89009
48464 - ENTH/VHS domain
89009 - GAT-like domain | 0 | DIRECT |
55729,55729
55729 - Acyl-CoA N-acyltransferases (Nat)
55729 - Acyl-CoA N-acyltransferases (Nat) | 0 | DIRECT |
51695,49562
51695 - PLC-like phosphodiesterases
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
49265,48726
49265 - Fibronectin type III
48726 - Immunoglobulin | 0 | DIRECT |
47954,47954
47954 - Cyclin-like
47954 - Cyclin-like | 0 | DIRECT |
51045,51045
51045 - WW domain
51045 - WW domain | 0 | DIRECT |
57756,50630
57756 - Retrovirus zinc finger-like domains
50630 - Acid proteases | 0 | DIRECT |
47413,46689
47413 - lambda repressor-like DNA-binding domains
46689 - Homeodomain-like | 0 | DIRECT |
52283,51735
52283 - Formate/glycerate dehydrogenase catalytic domain-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
64593,74853
64593 - Intermediate filament protein, coiled coil region
74853 - Lamin A/C globular tail domain | 0 | DIRECT |
52540,81271
52540 - P-loop containing nucleoside triphosphate hydrolases
81271 - TGS-like | 0 | DIRECT |
55920,46785
55920 - Creatinase/aminopeptidase
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
55486,57552
55486 - Metalloproteases ("zincins"), catalytic domain
57552 - Blood coagulation inhibitor (disintegrin) | 0 | DIRECT |
50249,55681
50249 - Nucleic acid-binding proteins
55681 - Class II aaRS and biotin synthetases | 0 | DIRECT |
56645,47203
56645 - Acyl-CoA dehydrogenase NM domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
47576,47576
47576 - Calponin-homology domain, CH-domain
47576 - Calponin-homology domain, CH-domain | 0 | DIRECT |
55973,55973
55973 - S-adenosylmethionine synthetase
55973 - S-adenosylmethionine synthetase | 0 | DIRECT |
81324,81296
81324 - Voltage-gated potassium channels
81296 - E set domains | 0 | DIRECT |
54849,52029
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0 | DIRECT |
56672,100879
56672 - DNA/RNA polymerases
100879 - Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
52540,140990
52540 - P-loop containing nucleoside triphosphate hydrolases
140990 - FtsH protease domain-like | 0 | DIRECT |
57889,48350
57889 - Cysteine-rich domain
48350 - GTPase activation domain, GAP | 0 | DIRECT |
56091,50249
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
49348,55711
49348 - Clathrin adaptor appendage domain
55711 - Subdomain of clathrin and coatomer appendage domain | 0 | DIRECT |
48179,48179
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | DIRECT |
51445,51011
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain | 0 | DIRECT |
55486,50923
55486 - Metalloproteases ("zincins"), catalytic domain
50923 - Hemopexin-like domain | 0 | DIRECT |
53738,53738
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains | 0 | DIRECT |
103473,103473
103473 - MFS general substrate transporter
103473 - MFS general substrate transporter | 0 | DIRECT |
48425,50729
48425 - Sec7 domain
50729 - PH domain-like | 0 | DIRECT |
144232,82199
144232 - HIT/MYND zinc finger-like
82199 - SET domain | 0 | DIRECT |
57889,50729
57889 - Cysteine-rich domain
50729 - PH domain-like | 0 | DIRECT |
57756,57756
57756 - Retrovirus zinc finger-like domains
57756 - Retrovirus zinc finger-like domains | 0 | DIRECT |
52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
47220,47220
47220 - alpha-catenin/vinculin-like
47220 - alpha-catenin/vinculin-like | 0 | DIRECT |
57850,117839
57850 - RING/U-box
117839 - WWE domain | 0 | DIRECT |
55394,55394
55394 - Bactericidal permeability-increasing protein, BPI
55394 - Bactericidal permeability-increasing protein, BPI | 0 | DIRECT |
48592,54849
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like | 0 | DIRECT |
141739,141739
141739 - MFPT repeat-like
141739 - MFPT repeat-like | 0 | DIRECT |
57184,57184
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | DIRECT |
68923,53795
68923 - PEP carboxykinase N-terminal domain
53795 - PEP carboxykinase-like | 0 | DIRECT |
47473,103506
47473 - EF-hand
103506 - Mitochondrial carrier | 0 | DIRECT |
50978,50998
50978 - WD40 repeat-like
50998 - Quinoprotein alcohol dehydrogenase-like | 0 | DIRECT |
141673,50800
141673 - MOSC N-terminal domain-like
50800 - PK beta-barrel domain-like | 0 | DIRECT |
51735,55347
51735 - NAD(P)-binding Rossmann-fold domains
55347 - Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | DIRECT |
75632,46785
75632 - Cullin homology domain
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
82895,82895
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat | 0 | DIRECT |
54768,54768
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like | 0 | DIRECT |
81324,53850
81324 - Voltage-gated potassium channels
53850 - Periplasmic binding protein-like II | 0 | DIRECT |
53187,55031
53187 - Zn-dependent exopeptidases
55031 - Bacterial exopeptidase dimerisation domain | 0 | DIRECT |
54695,81382
54695 - POZ domain
81382 - Skp1 dimerisation domain-like | 0 | DIRECT |
54160,54160
54160 - Chromo domain-like
54160 - Chromo domain-like | 0 | DIRECT |
47895,52540
47895 - Transducin (alpha subunit), insertion domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
52743,49785
52743 - Subtilisin-like
49785 - Galactose-binding domain-like | 0 | DIRECT |
51735,56327
51735 - NAD(P)-binding Rossmann-fold domains
56327 - LDH C-terminal domain-like | 0 | DIRECT |
81324,81327
81324 - Voltage-gated potassium channels
81327 - Small-conductance potassium channel | 0 | DIRECT |
81698,81698
81698 - FF domain
81698 - FF domain | 0 | DIRECT |
53067,100920
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
48371,56112
48371 - ARM repeat
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
50156,50044
50156 - PDZ domain-like
50044 - SH3-domain | 0 | DIRECT |
57903,51197
57903 - FYVE/PHD zinc finger
51197 - Clavaminate synthase-like | 0 | DIRECT |
50447,50465
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
82919,53300
82919 - Zn-finger domain of Sec23/24
53300 - vWA-like | 0 | DIRECT |
52540,90123
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region | 0 | DIRECT |
57196,57184
57196 - EGF/Laminin
57184 - Growth factor receptor domain | 0 | DIRECT |
47203,47203
47203 - Acyl-CoA dehydrogenase C-terminal domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
81383,52047
81383 - F-box domain
52047 - RNI-like | 0 | DIRECT |
52518,52518
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52518 - Thiamin diphosphate-binding fold (THDP-binding) | 0 | DIRECT |
54534,54534
54534 - FKBP-like
54534 - FKBP-like | 0 | DIRECT |
56059,52210
56059 - Glutathione synthetase ATP-binding domain-like
52210 - Succinyl-CoA synthetase domains | 0 | DIRECT |
57903,82199
57903 - FYVE/PHD zinc finger
82199 - SET domain | 0 | DIRECT |
57863,48403
57863 - ArfGap/RecO-like zinc finger
48403 - Ankyrin repeat | 0 | DIRECT |
52440,56059
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like | 0 | DIRECT |
52047,52047
52047 - RNI-like
52047 - RNI-like | 0 | DIRECT |
47741,56176
47741 - CO dehydrogenase ISP C-domain like
56176 - FAD-binding/transporter-associated domain-like | 0 | DIRECT |
49742,49742
49742 - PHM/PNGase F
49742 - PHM/PNGase F | 0 | DIRECT |
50692,54585
50692 - ADC-like
54585 - Cdc48 domain 2-like | 0 | DIRECT |
55681,52954
55681 - Class II aaRS and biotin synthetases
52954 - Class II aaRS ABD-related | 0 | DIRECT |
53901,53901
53901 - Thiolase-like
53901 - Thiolase-like | 0 | DIRECT |
57184,57196
57184 - Growth factor receptor domain
57196 - EGF/Laminin | 0 | DIRECT |
46938,52087
46938 - CRAL/TRIO N-terminal domain
52087 - CRAL/TRIO domain | 0 | DIRECT |
48065,50729
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like | 0 | DIRECT |
47587,56399
47587 - Domain of poly(ADP-ribose) polymerase
56399 - ADP-ribosylation | 0 | DIRECT |
54665,56003
54665 - CO dehydrogenase molybdoprotein N-domain-like
56003 - Molybdenum cofactor-binding domain | 0 | DIRECT |
57196,49899
57196 - EGF/Laminin
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
54211,55060
54211 - Ribosomal protein S5 domain 2-like
55060 - GHMP Kinase, C-terminal domain | 0 | DIRECT |
52374,47323
52374 - Nucleotidylyl transferase
47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
100920,100934
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
101690,53098
101690 - PAZ domain
53098 - Ribonuclease H-like | 0 | DIRECT |
56112,48371
56112 - Protein kinase-like (PK-like)
48371 - ARM repeat | 0 | DIRECT |
54236,54236
54236 - Ubiquitin-like
54236 - Ubiquitin-like | 0 | DIRECT |
49493,49493
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
52047,48371
52047 - RNI-like
48371 - ARM repeat | 0 | DIRECT |
74650,51445
74650 - Galactose mutarotase-like
51445 - (Trans)glycosidases | 0 | DIRECT |
48371,48371
48371 - ARM repeat
48371 - ARM repeat | 0 | DIRECT |
161111,160240
161111 - Cation efflux protein transmembrane domain-like
160240 - Cation efflux protein cytoplasmic domain-like | 0 | DIRECT |
52540,47917
52540 - P-loop containing nucleoside triphosphate hydrolases
47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
55785,55785
55785 - PYP-like sensor domain (PAS domain)
55785 - PYP-like sensor domain (PAS domain) | 0 | DIRECT |
48334,52540
48334 - DNA repair protein MutS, domain III
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
54897,52743
54897 - Protease propeptides/inhibitors
52743 - Subtilisin-like | 0 | DIRECT |
51905,56425
51905 - FAD/NAD(P)-binding domain
56425 - Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | DIRECT |
48403,52151
48403 - Ankyrin repeat
52151 - FabD/lysophospholipase-like | 0 | DIRECT |
64356,49447
64356 - SNARE-like
49447 - Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
55326,56042
55326 - PurM N-terminal domain-like
56042 - PurM C-terminal domain-like | 0 | DIRECT |
54495,46934
54495 - UBC-like
46934 - UBA-like | 0 | DIRECT |
50729,47473
50729 - PH domain-like
47473 - EF-hand | 0 | DIRECT |
53738,55957
53738 - Phosphoglucomutase, first 3 domains
55957 - Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
56112,82615
56112 - Protein kinase-like (PK-like)
82615 - Polo-box domain | 0 | DIRECT |
54292,47741
54292 - 2Fe-2S ferredoxin-like
47741 - CO dehydrogenase ISP C-domain like | 0 | DIRECT |
53187,49464
53187 - Zn-dependent exopeptidases
49464 - Carboxypeptidase regulatory domain-like | 0 | DIRECT |
56059,51246
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 0 | DIRECT |
49313,49313
49313 - Cadherin-like
49313 - Cadherin-like | 0 | DIRECT |
51556,51338
51556 - Metallo-dependent hydrolases
51338 - Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
50044,50044
50044 - SH3-domain
50044 - SH3-domain | 0 | DIRECT |
81383,50978
81383 - F-box domain
50978 - WD40 repeat-like | 0 | DIRECT |
46785,46785
46785 - "Winged helix" DNA-binding domain
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
81333,81333
81333 - F1F0 ATP synthase subunit C
81333 - F1F0 ATP synthase subunit C | 0 | DIRECT |
50677,52374
50677 - ValRS/IleRS/LeuRS editing domain
52374 - Nucleotidylyl transferase | 0 | DIRECT |
50729,56112
50729 - PH domain-like
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
50044,52540
50044 - SH3-domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
56601,48403
56601 - beta-lactamase/transpeptidase-like
48403 - Ankyrin repeat | 0 | DIRECT |
57535,57535
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | DIRECT |
53474,53474
53474 - alpha/beta-Hydrolases
53474 - alpha/beta-Hydrolases | 0 | DIRECT |
51905,55424
51905 - FAD/NAD(P)-binding domain
55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | DIRECT |
51206,51206
51206 - cAMP-binding domain-like
51206 - cAMP-binding domain-like | 0 | DIRECT |
82615,82615
82615 - Polo-box domain
82615 - Polo-box domain | 0 | DIRECT |
51445,51445
51445 - (Trans)glycosidases
51445 - (Trans)glycosidases | 0 | DIRECT |
50129,51735
50129 - GroES-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
54585,52540
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
53067,53067
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 0 | DIRECT |
55874,54211
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
54211 - Ribosomal protein S5 domain 2-like | 0 | DIRECT |
52518,52922
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52922 - TK C-terminal domain-like | 0 | DIRECT |
51735,50129
51735 - NAD(P)-binding Rossmann-fold domains
50129 - GroES-like | 0 | DIRECT |
81811,82754
81811 - Helical domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
51971,54373
51971 - Nucleotide-binding domain
54373 - FAD-linked reductases, C-terminal domain | 0 | DIRECT |
54001,49758
54001 - Cysteine proteinases
49758 - Calpain large subunit, middle domain (domain III) | 0 | DIRECT |
52490,55307
52490 - Tubulin nucleotide-binding domain-like
55307 - Tubulin C-terminal domain-like | 0 | DIRECT |
54236,47031
54236 - Ubiquitin-like
47031 - Second domain of FERM | 0 | DIRECT |
47769,47769
47769 - SAM/Pointed domain
47769 - SAM/Pointed domain | 0 | DIRECT |
81631,55003
81631 - PAP/OAS1 substrate-binding domain
55003 - PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | DIRECT |
81301,81631
81301 - Nucleotidyltransferase
81631 - PAP/OAS1 substrate-binding domain | 0 | DIRECT |
74788,75632
74788 - Cullin repeat-like
75632 - Cullin homology domain | 0 | DIRECT |
57196,63825
57196 - EGF/Laminin
63825 - YWTD domain | 0 | DIRECT |
50249,50249
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
161093,161093
161093 - MgtE membrane domain-like
161093 - MgtE membrane domain-like | 0 | DIRECT |
57889,57889
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0 | DIRECT |
47090,55486
47090 - PGBD-like
55486 - Metalloproteases ("zincins"), catalytic domain | 0 | DIRECT |
52540,46785
52540 - P-loop containing nucleoside triphosphate hydrolases
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
57938,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
51445,54556
51445 - (Trans)glycosidases
54556 - Chitinase insertion domain | 0 | DIRECT |
54160,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
47031,50729
47031 - Second domain of FERM
50729 - PH domain-like | 0 | DIRECT |
57414,57414
57414 - Hairpin loop containing domain-like
57414 - Hairpin loop containing domain-like | 0 | DIRECT |
90229,90229
90229 - CCCH zinc finger
90229 - CCCH zinc finger | 0 | DIRECT |
46966,46966
46966 - Spectrin repeat
46966 - Spectrin repeat | 0 | DIRECT |
57625,57625
57625 - Invertebrate chitin-binding proteins
57625 - Invertebrate chitin-binding proteins | 0 | DIRECT |
49562,48371
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat | 0 | DIRECT |
54897,53187
54897 - Protease propeptides/inhibitors
53187 - Zn-dependent exopeptidases | 0 | DIRECT |
55550,56112
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0.01709 | INHERITED FROM: slow growth || aldicarb resistant || acetylcholinesterase inhibitor resistant |
90123,52540
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.1261 | INHERITED FROM: colchicine hypersensitive || organism environmental stimulus response variant || cadmium response variant || metal response variant || RNAi response variant |
48452,48452
48452 - TPR-like
48452 - TPR-like | 0.1374 | INHERITED FROM: gene expression variant || organism environmental stimulus response variant || dauer defective || chemotaxis variant || pattern of transgene expression variant || aldicarb response variant || aqueous chemosensory response variant || positive chemotaxis defective |
56112,55073
56112 - Protein kinase-like (PK-like)
55073 - Nucleotide cyclase | 0.1521 | INHERITED FROM: AWC odorant chemotaxis defective || lithium chemotaxis defective || magnesium chemotaxis defective || benzaldehyde chemotaxis variant || AWC odorant chemotaxis variant || cation positive chemotaxis defective || iodide chemotaxis defective || anion positive chemotaxis defective || organism environmental stimulus response variant || cation positive chemotaxis variant || bromide chemotaxis defective || chemotaxis variant || chemical response variant || iodide chemotaxis variant || anion positive chemotaxis variant || chemosensory response variant || bromide chemotaxis variant || alkaline pH chemotaxis variant || positive chemotaxis variant || aqueous chemosensory response variant |
81660,56784
81660 - Metal cation-transporting ATPase, ATP-binding domain N
56784 - HAD-like | 0.1521 | INHERITED FROM: nicotine hypersensitive || drug hypersensitive || organism environmental stimulus response variant || lipid composition variant |
56436,56436
56436 - C-type lectin-like
56436 - C-type lectin-like | 0.1909 | INHERITED FROM: cadmium hypersensitive |
52540,50447
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins | 0.2279 | INHERITED FROM: transgene expression variant || protein phosphorylation variant || protein phosphorylation increased || extended life span || protein modification variant || protein aggregation variant || mRNA levels reduced || protein protein interaction variant || mRNA levels increased |
51735,48179
51735 - NAD(P)-binding Rossmann-fold domains
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0.2775 | INHERITED FROM: lipid metabolism variant || fat content variant |
56436,49854
56436 - C-type lectin-like
49854 - Spermadhesin, CUB domain | 0.2775 | INHERITED FROM: cadmium hypersensitive || cadmium response variant |
56784,81665
56784 - HAD-like
81665 - Calcium ATPase, transmembrane domain M | 0.2775 | INHERITED FROM: nicotine hypersensitive || drug hypersensitive || organism environmental stimulus response variant |
49785,49785
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like | 0.3062 | INHERITED FROM: protein interaction variant || protein aggregation variant || protein protein interaction variant |
50978,50978
50978 - WD40 repeat-like
50978 - WD40 repeat-like | 0.3375 | INHERITED FROM: mechanosensation variant || aqueous positive chemotaxis defective || dauer defective || chemotaxis variant || aqueous positive chemotaxis variant || positive chemotaxis variant || aqueous chemosensory response variant || positive chemotaxis defective |
50156,50156
50156 - PDZ domain-like
50156 - PDZ domain-like | 0.3718 | INHERITED FROM: protein subcellular localization variant |
47473,47473
47473 - EF-hand
47473 - EF-hand | 0.3718 | INHERITED FROM: acetylcholinesterase inhibitor hypersensitive || aldicarb response variant || acetylcholinesterase inhibitor response variant |
63712,90112
63712 - Nicotinic receptor ligand binding domain-like
90112 - Neurotransmitter-gated ion-channel transmembrane pore | 0.3935 | INHERITED FROM: antihelmintic response variant || drug response variant || mechanosensation variant || nicotine resistant || organism environmental stimulus response variant || cholinergic agonist resistant || sodium chloride chemotaxis variant || chemical response variant || DMPP response variant || hypoosmotic shock hypersensitive || selenium response variant || positive chemotaxis variant || aqueous chemosensory response variant |
54928,54928
54928 - RNA-binding domain, RBD
54928 - RNA-binding domain, RBD | 0.3975 | INHERITED FROM: late larval arrest || organism starvation response variant || gene expression variant || starvation induced apoptosis variant |
52833,52833
52833 - Thioredoxin-like
52833 - Thioredoxin-like | 0.4092 | INHERITED FROM: protein interaction variant || transgene subcellular localization variant || protein aggregation variant || pattern of transgene expression variant || protein protein interaction variant |
48403,48403
48403 - Ankyrin repeat
48403 - Ankyrin repeat | 0.4947 | INHERITED FROM: organism environmental stimulus response variant |
57716,57716
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0.5164 | INHERITED FROM: protein expression variant || gene expression variant || organism metabolism processing variant || protein expression reduced |
57196,57196
57196 - EGF/Laminin
57196 - EGF/Laminin | 0.522 | INHERITED FROM: growth rate variant || protein expression reduced |
57716,48508
57716 - Glucocorticoid receptor-like (DNA-binding domain)
48508 - Nuclear receptor ligand-binding domain | 0.5243 | INHERITED FROM: chemical hypersensitive || dauer resistance to harsh conditions variant || SDS sensitive dauer || transgene expression reduced |
52833,47616
52833 - Thioredoxin-like
47616 - GST C-terminal domain-like | 0.5827 | INHERITED FROM: organism electrophilic stress hypersensitive || organism stress response variant || enzyme activity variant || paraquat response variant || organism environmental stimulus response variant || organism heat hypersensitive || cadmium hypersensitive || cadmium response variant || enzyme activity reduced |
50044,55550
50044 - SH3-domain
55550 - SH2 domain | 0.5931 | INHERITED FROM: protein expression reduced |
63380,52343
63380 - Riboflavin synthase domain-like
52343 - Ferredoxin reductase-like, C-terminal NADP-linked domain | 0.65 | INHERITED FROM: transgene subcellular localization variant |
48431,56968
48431 - Lipovitellin-phosvitin complex, superhelical domain
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions | 0.65 | INHERITED FROM: life span variant || transgene subcellular localization variant || organism environmental stimulus response variant || pathogen susceptibility increased || organism pathogen response variant |
56968,48431
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
48431 - Lipovitellin-phosvitin complex, superhelical domain | 0.65 | INHERITED FROM: life span variant || transgene subcellular localization variant || organism environmental stimulus response variant || pathogen susceptibility increased || organism pathogen response variant |
57424,57424
57424 - LDL receptor-like module
57424 - LDL receptor-like module | 0.694 | INHERITED FROM: protein expression reduced |
51905,54373
51905 - FAD/NAD(P)-binding domain
54373 - FAD-linked reductases, C-terminal domain | 0.694 | INHERITED FROM: shortened life span || life span variant |
57903,57903
57903 - FYVE/PHD zinc finger
57903 - FYVE/PHD zinc finger | 0.7131 | INHERITED FROM: organism UV hypersensitive || organism environmental stimulus response variant || organism UV response variant |
55550,50044
55550 - SH2 domain
50044 - SH3-domain | 0.7811 | INHERITED FROM: protein expression variant || level of protein expression variant || protein expression reduced |
48726,49265
48726 - Immunoglobulin
49265 - Fibronectin type III | 0.8682 | INHERITED FROM: aldicarb resistant || growth rate variant || chemical response variant |
48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin | 0.9193 | INHERITED FROM: growth rate variant |
54211,55666
54211 - Ribosomal protein S5 domain 2-like
55666 - Ribonuclease PH domain 2-like | 0.9627 | INHERITED FROM: early larval arrest |
49562,49562
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0.9719 | INHERITED FROM: drug resistant |
57850,57850
57850 - RING/U-box
57850 - RING/U-box | 1 | INHERITED FROM: protein interaction variant || transgene subcellular localization variant || protein aggregation variant || pattern of transgene expression variant || protein protein interaction variant |
57850,57845
57850 - RING/U-box
57845 - B-box zinc-binding domain | 1 | INHERITED FROM: protein interaction variant || transgene subcellular localization variant || protein aggregation variant || protein protein interaction variant |
52777,52777
52777 - CoA-dependent acyltransferases
52777 - CoA-dependent acyltransferases | 1 | INHERITED FROM: lipid metabolism variant || fat content variant |
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
51338,51556
51338 - Composite domain of metallo-dependent hydrolases
51556 - Metallo-dependent hydrolases | 0 | Direct |
57362,57362
57362 - BPTI-like
57362 - BPTI-like | 0 | Direct |
52113,52113
52113 - BRCT domain
52113 - BRCT domain | 0 | Direct |
47473,51695
47473 - EF-hand
51695 - PLC-like phosphodiesterases | 0 | Direct |
48464,89009
48464 - ENTH/VHS domain
89009 - GAT-like domain | 0 | Direct |
55729,55729
55729 - Acyl-CoA N-acyltransferases (Nat)
55729 - Acyl-CoA N-acyltransferases (Nat) | 0 | Direct |
51695,49562
51695 - PLC-like phosphodiesterases
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
49265,48726
49265 - Fibronectin type III
48726 - Immunoglobulin | 0 | Direct |
47954,47954
47954 - Cyclin-like
47954 - Cyclin-like | 0 | Direct |
51045,51045
51045 - WW domain
51045 - WW domain | 0 | Direct |
57756,50630
57756 - Retrovirus zinc finger-like domains
50630 - Acid proteases | 0 | Direct |
47413,46689
47413 - lambda repressor-like DNA-binding domains
46689 - Homeodomain-like | 0 | Direct |
52283,51735
52283 - Formate/glycerate dehydrogenase catalytic domain-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | Direct |
64593,74853
64593 - Intermediate filament protein, coiled coil region
74853 - Lamin A/C globular tail domain | 0 | Direct |
52540,81271
52540 - P-loop containing nucleoside triphosphate hydrolases
81271 - TGS-like | 0 | Direct |
55920,46785
55920 - Creatinase/aminopeptidase
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
55486,57552
55486 - Metalloproteases ("zincins"), catalytic domain
57552 - Blood coagulation inhibitor (disintegrin) | 0 | Direct |
50249,55681
50249 - Nucleic acid-binding proteins
55681 - Class II aaRS and biotin synthetases | 0 | Direct |
56645,47203
56645 - Acyl-CoA dehydrogenase NM domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
47576,47576
47576 - Calponin-homology domain, CH-domain
47576 - Calponin-homology domain, CH-domain | 0 | Direct |
55973,55973
55973 - S-adenosylmethionine synthetase
55973 - S-adenosylmethionine synthetase | 0 | Direct |
81324,81296
81324 - Voltage-gated potassium channels
81296 - E set domains | 0 | Direct |
54849,52029
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0 | Direct |
56672,100879
56672 - DNA/RNA polymerases
100879 - Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
52540,140990
52540 - P-loop containing nucleoside triphosphate hydrolases
140990 - FtsH protease domain-like | 0 | Direct |
57889,48350
57889 - Cysteine-rich domain
48350 - GTPase activation domain, GAP | 0 | Direct |
56091,50249
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins | 0 | Direct |
49348,55711
49348 - Clathrin adaptor appendage domain
55711 - Subdomain of clathrin and coatomer appendage domain | 0 | Direct |
48179,48179
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | Direct |
51445,51011
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain | 0 | Direct |
55486,50923
55486 - Metalloproteases ("zincins"), catalytic domain
50923 - Hemopexin-like domain | 0 | Direct |
53738,53738
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains | 0 | Direct |
103473,103473
103473 - MFS general substrate transporter
103473 - MFS general substrate transporter | 0 | Direct |
48425,50729
48425 - Sec7 domain
50729 - PH domain-like | 0 | Direct |
144232,82199
144232 - HIT/MYND zinc finger-like
82199 - SET domain | 0 | Direct |
57889,50729
57889 - Cysteine-rich domain
50729 - PH domain-like | 0 | Direct |
57756,57756
57756 - Retrovirus zinc finger-like domains
57756 - Retrovirus zinc finger-like domains | 0 | Direct |
52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
47220,47220
47220 - alpha-catenin/vinculin-like
47220 - alpha-catenin/vinculin-like | 0 | Direct |
57850,117839
57850 - RING/U-box
117839 - WWE domain | 0 | Direct |
55394,55394
55394 - Bactericidal permeability-increasing protein, BPI
55394 - Bactericidal permeability-increasing protein, BPI | 0 | Direct |
48592,54849
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like | 0 | Direct |
141739,141739
141739 - MFPT repeat-like
141739 - MFPT repeat-like | 0 | Direct |
57184,57184
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | Direct |
68923,53795
68923 - PEP carboxykinase N-terminal domain
53795 - PEP carboxykinase-like | 0 | Direct |
47473,103506
47473 - EF-hand
103506 - Mitochondrial carrier | 0 | Direct |
50978,50998
50978 - WD40 repeat-like
50998 - Quinoprotein alcohol dehydrogenase-like | 0 | Direct |
141673,50800
141673 - MOSC N-terminal domain-like
50800 - PK beta-barrel domain-like | 0 | Direct |
51735,55347
51735 - NAD(P)-binding Rossmann-fold domains
55347 - Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | Direct |
75632,46785
75632 - Cullin homology domain
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
82895,82895
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat | 0 | Direct |
54768,54768
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like | 0 | Direct |
81324,53850
81324 - Voltage-gated potassium channels
53850 - Periplasmic binding protein-like II | 0 | Direct |
53187,55031
53187 - Zn-dependent exopeptidases
55031 - Bacterial exopeptidase dimerisation domain | 0 | Direct |
54695,81382
54695 - POZ domain
81382 - Skp1 dimerisation domain-like | 0 | Direct |
54160,54160
54160 - Chromo domain-like
54160 - Chromo domain-like | 0 | Direct |
47895,52540
47895 - Transducin (alpha subunit), insertion domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
52743,49785
52743 - Subtilisin-like
49785 - Galactose-binding domain-like | 0 | Direct |
51735,56327
51735 - NAD(P)-binding Rossmann-fold domains
56327 - LDH C-terminal domain-like | 0 | Direct |
81324,81327
81324 - Voltage-gated potassium channels
81327 - Small-conductance potassium channel | 0 | Direct |
81698,81698
81698 - FF domain
81698 - FF domain | 0 | Direct |
53067,100920
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
48371,56112
48371 - ARM repeat
56112 - Protein kinase-like (PK-like) | 0 | Direct |
50156,50044
50156 - PDZ domain-like
50044 - SH3-domain | 0 | Direct |
57903,51197
57903 - FYVE/PHD zinc finger
51197 - Clavaminate synthase-like | 0 | Direct |
50447,50465
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
82919,53300
82919 - Zn-finger domain of Sec23/24
53300 - vWA-like | 0 | Direct |
52540,90123
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region | 0 | Direct |
57196,57184
57196 - EGF/Laminin
57184 - Growth factor receptor domain | 0 | Direct |
47203,47203
47203 - Acyl-CoA dehydrogenase C-terminal domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
81383,52047
81383 - F-box domain
52047 - RNI-like | 0 | Direct |
52518,52518
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52518 - Thiamin diphosphate-binding fold (THDP-binding) | 0 | Direct |
54534,54534
54534 - FKBP-like
54534 - FKBP-like | 0 | Direct |
56059,52210
56059 - Glutathione synthetase ATP-binding domain-like
52210 - Succinyl-CoA synthetase domains | 0 | Direct |
57903,82199
57903 - FYVE/PHD zinc finger
82199 - SET domain | 0 | Direct |
57863,48403
57863 - ArfGap/RecO-like zinc finger
48403 - Ankyrin repeat | 0 | Direct |
52440,56059
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like | 0 | Direct |
52047,52047
52047 - RNI-like
52047 - RNI-like | 0 | Direct |
47741,56176
47741 - CO dehydrogenase ISP C-domain like
56176 - FAD-binding/transporter-associated domain-like | 0 | Direct |
49742,49742
49742 - PHM/PNGase F
49742 - PHM/PNGase F | 0 | Direct |
50692,54585
50692 - ADC-like
54585 - Cdc48 domain 2-like | 0 | Direct |
55681,52954
55681 - Class II aaRS and biotin synthetases
52954 - Class II aaRS ABD-related | 0 | Direct |
53901,53901
53901 - Thiolase-like
53901 - Thiolase-like | 0 | Direct |
57184,57196
57184 - Growth factor receptor domain
57196 - EGF/Laminin | 0 | Direct |
46938,52087
46938 - CRAL/TRIO N-terminal domain
52087 - CRAL/TRIO domain | 0 | Direct |
48065,50729
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like | 0 | Direct |
47587,56399
47587 - Domain of poly(ADP-ribose) polymerase
56399 - ADP-ribosylation | 0 | Direct |
54665,56003
54665 - CO dehydrogenase molybdoprotein N-domain-like
56003 - Molybdenum cofactor-binding domain | 0 | Direct |
57196,49899
57196 - EGF/Laminin
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
54211,55060
54211 - Ribosomal protein S5 domain 2-like
55060 - GHMP Kinase, C-terminal domain | 0 | Direct |
52374,47323
52374 - Nucleotidylyl transferase
47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
100920,100934
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
101690,53098
101690 - PAZ domain
53098 - Ribonuclease H-like | 0 | Direct |
56112,48371
56112 - Protein kinase-like (PK-like)
48371 - ARM repeat | 0 | Direct |
54236,54236
54236 - Ubiquitin-like
54236 - Ubiquitin-like | 0 | Direct |
49493,49493
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
52047,48371
52047 - RNI-like
48371 - ARM repeat | 0 | Direct |
74650,51445
74650 - Galactose mutarotase-like
51445 - (Trans)glycosidases | 0 | Direct |
48371,48371
48371 - ARM repeat
48371 - ARM repeat | 0 | Direct |
161111,160240
161111 - Cation efflux protein transmembrane domain-like
160240 - Cation efflux protein cytoplasmic domain-like | 0 | Direct |
52540,47917
52540 - P-loop containing nucleoside triphosphate hydrolases
47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
55785,55785
55785 - PYP-like sensor domain (PAS domain)
55785 - PYP-like sensor domain (PAS domain) | 0 | Direct |
48334,52540
48334 - DNA repair protein MutS, domain III
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
54897,52743
54897 - Protease propeptides/inhibitors
52743 - Subtilisin-like | 0 | Direct |
51905,56425
51905 - FAD/NAD(P)-binding domain
56425 - Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | Direct |
48403,52151
48403 - Ankyrin repeat
52151 - FabD/lysophospholipase-like | 0 | Direct |
64356,49447
64356 - SNARE-like
49447 - Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
55326,56042
55326 - PurM N-terminal domain-like
56042 - PurM C-terminal domain-like | 0 | Direct |
54495,46934
54495 - UBC-like
46934 - UBA-like | 0 | Direct |
50729,47473
50729 - PH domain-like
47473 - EF-hand | 0 | Direct |
53738,55957
53738 - Phosphoglucomutase, first 3 domains
55957 - Phosphoglucomutase, C-terminal domain | 0 | Direct |
56112,82615
56112 - Protein kinase-like (PK-like)
82615 - Polo-box domain | 0 | Direct |
54292,47741
54292 - 2Fe-2S ferredoxin-like
47741 - CO dehydrogenase ISP C-domain like | 0 | Direct |
53187,49464
53187 - Zn-dependent exopeptidases
49464 - Carboxypeptidase regulatory domain-like | 0 | Direct |
56059,51246
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 0 | Direct |
49313,49313
49313 - Cadherin-like
49313 - Cadherin-like | 0 | Direct |
51556,51338
51556 - Metallo-dependent hydrolases
51338 - Composite domain of metallo-dependent hydrolases | 0 | Direct |
50044,50044
50044 - SH3-domain
50044 - SH3-domain | 0 | Direct |
81383,50978
81383 - F-box domain
50978 - WD40 repeat-like | 0 | Direct |
46785,46785
46785 - "Winged helix" DNA-binding domain
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
81333,81333
81333 - F1F0 ATP synthase subunit C
81333 - F1F0 ATP synthase subunit C | 0 | Direct |
50677,52374
50677 - ValRS/IleRS/LeuRS editing domain
52374 - Nucleotidylyl transferase | 0 | Direct |
50729,56112
50729 - PH domain-like
56112 - Protein kinase-like (PK-like) | 0 | Direct |
50044,52540
50044 - SH3-domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
56601,48403
56601 - beta-lactamase/transpeptidase-like
48403 - Ankyrin repeat | 0 | Direct |
57535,57535
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | Direct |
53474,53474
53474 - alpha/beta-Hydrolases
53474 - alpha/beta-Hydrolases | 0 | Direct |
51905,55424
51905 - FAD/NAD(P)-binding domain
55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | Direct |
51206,51206
51206 - cAMP-binding domain-like
51206 - cAMP-binding domain-like | 0 | Direct |
82615,82615
82615 - Polo-box domain
82615 - Polo-box domain | 0 | Direct |
51445,51445
51445 - (Trans)glycosidases
51445 - (Trans)glycosidases | 0 | Direct |
50129,51735
50129 - GroES-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | Direct |
54585,52540
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
53067,53067
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 0 | Direct |
55874,54211
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
54211 - Ribosomal protein S5 domain 2-like | 0 | Direct |
52518,52922
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52922 - TK C-terminal domain-like | 0 | Direct |
51735,50129
51735 - NAD(P)-binding Rossmann-fold domains
50129 - GroES-like | 0 | Direct |
81811,82754
81811 - Helical domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
51971,54373
51971 - Nucleotide-binding domain
54373 - FAD-linked reductases, C-terminal domain | 0 | Direct |
54001,49758
54001 - Cysteine proteinases
49758 - Calpain large subunit, middle domain (domain III) | 0 | Direct |
52490,55307
52490 - Tubulin nucleotide-binding domain-like
55307 - Tubulin C-terminal domain-like | 0 | Direct |
54236,47031
54236 - Ubiquitin-like
47031 - Second domain of FERM | 0 | Direct |
47769,47769
47769 - SAM/Pointed domain
47769 - SAM/Pointed domain | 0 | Direct |
81631,55003
81631 - PAP/OAS1 substrate-binding domain
55003 - PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | Direct |
81301,81631
81301 - Nucleotidyltransferase
81631 - PAP/OAS1 substrate-binding domain | 0 | Direct |
74788,75632
74788 - Cullin repeat-like
75632 - Cullin homology domain | 0 | Direct |
57196,63825
57196 - EGF/Laminin
63825 - YWTD domain | 0 | Direct |
50249,50249
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins | 0 | Direct |
161093,161093
161093 - MgtE membrane domain-like
161093 - MgtE membrane domain-like | 0 | Direct |
57889,57889
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0 | Direct |
47090,55486
47090 - PGBD-like
55486 - Metalloproteases ("zincins"), catalytic domain | 0 | Direct |
52540,46785
52540 - P-loop containing nucleoside triphosphate hydrolases
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
57938,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
51445,54556
51445 - (Trans)glycosidases
54556 - Chitinase insertion domain | 0 | Direct |
54160,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
47031,50729
47031 - Second domain of FERM
50729 - PH domain-like | 0 | Direct |
57414,57414
57414 - Hairpin loop containing domain-like
57414 - Hairpin loop containing domain-like | 0 | Direct |
90229,90229
90229 - CCCH zinc finger
90229 - CCCH zinc finger | 0 | Direct |
46966,46966
46966 - Spectrin repeat
46966 - Spectrin repeat | 0 | Direct |
57625,57625
57625 - Invertebrate chitin-binding proteins
57625 - Invertebrate chitin-binding proteins | 0 | Direct |
49562,48371
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat | 0 | Direct |
54897,53187
54897 - Protease propeptides/inhibitors
53187 - Zn-dependent exopeptidases | 0 | Direct |
55550,56112
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0.01709 | Inherited |
90123,52540
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.1261 | Inherited |
48452,48452
48452 - TPR-like
48452 - TPR-like | 0.1374 | Inherited |
56112,55073
56112 - Protein kinase-like (PK-like)
55073 - Nucleotide cyclase | 0.1521 | Inherited |
81660,56784
81660 - Metal cation-transporting ATPase, ATP-binding domain N
56784 - HAD-like | 0.1521 | Inherited |
56436,56436
56436 - C-type lectin-like
56436 - C-type lectin-like | 0.1909 | Inherited |
52540,50447
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins | 0.2279 | Inherited |
51735,48179
51735 - NAD(P)-binding Rossmann-fold domains
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0.2775 | Inherited |
56436,49854
56436 - C-type lectin-like
49854 - Spermadhesin, CUB domain | 0.2775 | Inherited |
56784,81665
56784 - HAD-like
81665 - Calcium ATPase, transmembrane domain M | 0.2775 | Inherited |
49785,49785
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like | 0.3062 | Inherited |
50978,50978
50978 - WD40 repeat-like
50978 - WD40 repeat-like | 0.3375 | Inherited |
50156,50156
50156 - PDZ domain-like
50156 - PDZ domain-like | 0.3718 | Inherited |
47473,47473
47473 - EF-hand
47473 - EF-hand | 0.3718 | Inherited |
63712,90112
63712 - Nicotinic receptor ligand binding domain-like
90112 - Neurotransmitter-gated ion-channel transmembrane pore | 0.3935 | Inherited |
54928,54928
54928 - RNA-binding domain, RBD
54928 - RNA-binding domain, RBD | 0.3975 | Inherited |
52833,52833
52833 - Thioredoxin-like
52833 - Thioredoxin-like | 0.4092 | Inherited |
48403,48403
48403 - Ankyrin repeat
48403 - Ankyrin repeat | 0.4947 | Inherited |
57716,57716
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0.5164 | Inherited |
57196,57196
57196 - EGF/Laminin
57196 - EGF/Laminin | 0.522 | Inherited |
57716,48508
57716 - Glucocorticoid receptor-like (DNA-binding domain)
48508 - Nuclear receptor ligand-binding domain | 0.5243 | Inherited |
52833,47616
52833 - Thioredoxin-like
47616 - GST C-terminal domain-like | 0.5827 | Inherited |
50044,55550
50044 - SH3-domain
55550 - SH2 domain | 0.5931 | Inherited |
63380,52343
63380 - Riboflavin synthase domain-like
52343 - Ferredoxin reductase-like, C-terminal NADP-linked domain | 0.65 | Inherited |
48431,56968
48431 - Lipovitellin-phosvitin complex, superhelical domain
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions | 0.65 | Inherited |
56968,48431
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
48431 - Lipovitellin-phosvitin complex, superhelical domain | 0.65 | Inherited |
57424,57424
57424 - LDL receptor-like module
57424 - LDL receptor-like module | 0.694 | Inherited |
51905,54373
51905 - FAD/NAD(P)-binding domain
54373 - FAD-linked reductases, C-terminal domain | 0.694 | Inherited |
57903,57903
57903 - FYVE/PHD zinc finger
57903 - FYVE/PHD zinc finger | 0.7131 | Inherited |
55550,50044
55550 - SH2 domain
50044 - SH3-domain | 0.7811 | Inherited |
48726,49265
48726 - Immunoglobulin
49265 - Fibronectin type III | 0.8682 | Inherited |
48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin | 0.9193 | Inherited |
54211,55666
54211 - Ribosomal protein S5 domain 2-like
55666 - Ribonuclease PH domain 2-like | 0.9627 | Inherited |
49562,49562
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0.9719 | Inherited |
57850,57850
57850 - RING/U-box
57850 - RING/U-box | 1 | Inherited |
57850,57845
57850 - RING/U-box
57845 - B-box zinc-binding domain | 1 | Inherited |
52777,52777
52777 - CoA-dependent acyltransferases
52777 - CoA-dependent acyltransferases | 1 | Inherited |
(show details)
Supra-domains annotated to this WP term (Not in SPWP)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
53738,53738,53738
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains | 0 | DIRECT |
49313,49313,49313
49313 - Cadherin-like
49313 - Cadherin-like
49313 - Cadherin-like | 0 | DIRECT |
48592,54849,52029
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0 | DIRECT |
50156,50044,52540
50156 - PDZ domain-like
50044 - SH3-domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
47090,55486,50923
47090 - PGBD-like
55486 - Metalloproteases ("zincins"), catalytic domain
50923 - Hemopexin-like domain | 0 | DIRECT |
52540,90123,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
54160,54160,52540
54160 - Chromo domain-like
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
48371,48371,48371
48371 - ARM repeat
48371 - ARM repeat
48371 - ARM repeat | 0 | DIRECT |
49785,49785,49785
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like | 0 | DIRECT |
53067,100920,100934
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
81301,81631,55003
81301 - Nucleotidyltransferase
81631 - PAP/OAS1 substrate-binding domain
55003 - PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | DIRECT |
57567,57567,57567
57567 - Serine protease inhibitors
57567 - Serine protease inhibitors
57567 - Serine protease inhibitors | 0 | DIRECT |
54928,54928,54928
54928 - RNA-binding domain, RBD
54928 - RNA-binding domain, RBD
54928 - RNA-binding domain, RBD | 0 | DIRECT |
52540,52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
48452,48452,48452
48452 - TPR-like
48452 - TPR-like
48452 - TPR-like | 0 | DIRECT |
63411,63411,63411
63411 - LuxS/MPP-like metallohydrolase
63411 - LuxS/MPP-like metallohydrolase
63411 - LuxS/MPP-like metallohydrolase | 0 | DIRECT |
54292,47741,56176
54292 - 2Fe-2S ferredoxin-like
47741 - CO dehydrogenase ISP C-domain like
56176 - FAD-binding/transporter-associated domain-like | 0 | DIRECT |
54160,52540,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
74788,75632,46785
74788 - Cullin repeat-like
75632 - Cullin homology domain
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
50249,50249,50249
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
51735,48179,48179
51735 - NAD(P)-binding Rossmann-fold domains
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | DIRECT |
52540,50447,50465
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
54585,52540,52540
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
57362,57362,57362
57362 - BPTI-like
57362 - BPTI-like
57362 - BPTI-like | 0 | DIRECT |
57535,57535,57535
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | DIRECT |
50729,47473,51695
50729 - PH domain-like
47473 - EF-hand
51695 - PLC-like phosphodiesterases | 0 | DIRECT |
55973,55973,55973
55973 - S-adenosylmethionine synthetase
55973 - S-adenosylmethionine synthetase
55973 - S-adenosylmethionine synthetase | 0 | DIRECT |
82895,82895,82895
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat | 0 | DIRECT |
74650,51445,51011
74650 - Galactose mutarotase-like
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain | 0 | DIRECT |
54236,47031,50729
54236 - Ubiquitin-like
47031 - Second domain of FERM
50729 - PH domain-like | 0 | DIRECT |
50692,54585,52540
50692 - ADC-like
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
56645,47203,47203
56645 - Acyl-CoA dehydrogenase NM domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
48726,49265,48726
48726 - Immunoglobulin
49265 - Fibronectin type III
48726 - Immunoglobulin | 0 | DIRECT |
49562,48371,56112
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
56436,49854,49854
56436 - C-type lectin-like
49854 - Spermadhesin, CUB domain
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
56112,82615,82615
56112 - Protein kinase-like (PK-like)
82615 - Polo-box domain
82615 - Polo-box domain | 0 | DIRECT |
50044,55550,56112
50044 - SH3-domain
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
46966,46966,46966
46966 - Spectrin repeat
46966 - Spectrin repeat
46966 - Spectrin repeat | 0 | DIRECT |
49899,49899,49899
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
53067,53067,100920
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
57938,49493,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
46938,52087,101576
46938 - CRAL/TRIO N-terminal domain
52087 - CRAL/TRIO domain
101576 - Supernatant protein factor (SPF), C-terminal domain | 0 | DIRECT |
50129,51735,50129
50129 - GroES-like
51735 - NAD(P)-binding Rossmann-fold domains
50129 - GroES-like | 0 | DIRECT |
53738,53738,55957
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains
55957 - Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
54897,52743,49785
54897 - Protease propeptides/inhibitors
52743 - Subtilisin-like
49785 - Galactose-binding domain-like | 0 | DIRECT |
50044,50044,50044
50044 - SH3-domain
50044 - SH3-domain
50044 - SH3-domain | 0 | DIRECT |
52440,56059,51246
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 0 | DIRECT |
57625,57625,57625
57625 - Invertebrate chitin-binding proteins
57625 - Invertebrate chitin-binding proteins
57625 - Invertebrate chitin-binding proteins | 0 | DIRECT |
90123,52540,90123
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region | 0 | DIRECT |
57414,57414,57414
57414 - Hairpin loop containing domain-like
57414 - Hairpin loop containing domain-like
57414 - Hairpin loop containing domain-like | 0 | DIRECT |
81660,56784,81665
81660 - Metal cation-transporting ATPase, ATP-binding domain N
56784 - HAD-like
81665 - Calcium ATPase, transmembrane domain M | 0.1683 | INHERITED FROM: nicotine hypersensitive || drug hypersensitive || organism environmental stimulus response variant || lipid composition variant |
57424,57424,57424
57424 - LDL receptor-like module
57424 - LDL receptor-like module
57424 - LDL receptor-like module | 0.4092 | INHERITED FROM: level of protein expression variant || protein expression reduced |
56436,56436,49854
56436 - C-type lectin-like
56436 - C-type lectin-like
49854 - Spermadhesin, CUB domain | 0.4242 | INHERITED FROM: cadmium hypersensitive || cadmium response variant || metal response variant |
52833,52833,52833
52833 - Thioredoxin-like
52833 - Thioredoxin-like
52833 - Thioredoxin-like | 0.4947 | INHERITED FROM: protein interaction variant || transgene expression increased || transgene subcellular localization variant || protein aggregation variant || pattern of transgene expression variant || protein protein interaction variant |
57716,57716,57716
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0.4947 | INHERITED FROM: protein expression variant || level of protein expression variant || gene expression variant || protein expression reduced |
56968,48431,56968
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
48431 - Lipovitellin-phosvitin complex, superhelical domain
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions | 0.65 | INHERITED FROM: life span variant || transgene subcellular localization variant || organism environmental stimulus response variant || pathogen susceptibility increased || organism pathogen response variant |
57850,57850,57850
57850 - RING/U-box
57850 - RING/U-box
57850 - RING/U-box | 0.8896 | INHERITED FROM: protein interaction variant || transgene expression variant || gene expression variant || transgene subcellular localization variant || protein aggregation variant || pattern of transgene expression variant || protein protein interaction variant |
48726,48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin
48726 - Immunoglobulin | 0.9988 | INHERITED FROM: growth rate variant |
48726,48726,49265
48726 - Immunoglobulin
48726 - Immunoglobulin
49265 - Fibronectin type III | 1 | INHERITED FROM: growth rate variant |
57667,57667,57667
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers | 1 | INHERITED FROM: level of transgene expression variant |
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
53738,53738,53738
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains | 0 | Direct |
49313,49313,49313
49313 - Cadherin-like
49313 - Cadherin-like
49313 - Cadherin-like | 0 | Direct |
48592,54849,52029
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0 | Direct |
50156,50044,52540
50156 - PDZ domain-like
50044 - SH3-domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
47090,55486,50923
47090 - PGBD-like
55486 - Metalloproteases ("zincins"), catalytic domain
50923 - Hemopexin-like domain | 0 | Direct |
52540,90123,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
54160,54160,52540
54160 - Chromo domain-like
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
48371,48371,48371
48371 - ARM repeat
48371 - ARM repeat
48371 - ARM repeat | 0 | Direct |
49785,49785,49785
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like | 0 | Direct |
53067,100920,100934
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
81301,81631,55003
81301 - Nucleotidyltransferase
81631 - PAP/OAS1 substrate-binding domain
55003 - PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | Direct |
57567,57567,57567
57567 - Serine protease inhibitors
57567 - Serine protease inhibitors
57567 - Serine protease inhibitors | 0 | Direct |
54928,54928,54928
54928 - RNA-binding domain, RBD
54928 - RNA-binding domain, RBD
54928 - RNA-binding domain, RBD | 0 | Direct |
52540,52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
48452,48452,48452
48452 - TPR-like
48452 - TPR-like
48452 - TPR-like | 0 | Direct |
63411,63411,63411
63411 - LuxS/MPP-like metallohydrolase
63411 - LuxS/MPP-like metallohydrolase
63411 - LuxS/MPP-like metallohydrolase | 0 | Direct |
54292,47741,56176
54292 - 2Fe-2S ferredoxin-like
47741 - CO dehydrogenase ISP C-domain like
56176 - FAD-binding/transporter-associated domain-like | 0 | Direct |
54160,52540,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
74788,75632,46785
74788 - Cullin repeat-like
75632 - Cullin homology domain
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
50249,50249,50249
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins | 0 | Direct |
51735,48179,48179
51735 - NAD(P)-binding Rossmann-fold domains
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | Direct |
52540,50447,50465
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
54585,52540,52540
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
57362,57362,57362
57362 - BPTI-like
57362 - BPTI-like
57362 - BPTI-like | 0 | Direct |
57535,57535,57535
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | Direct |
50729,47473,51695
50729 - PH domain-like
47473 - EF-hand
51695 - PLC-like phosphodiesterases | 0 | Direct |
55973,55973,55973
55973 - S-adenosylmethionine synthetase
55973 - S-adenosylmethionine synthetase
55973 - S-adenosylmethionine synthetase | 0 | Direct |
82895,82895,82895
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat | 0 | Direct |
74650,51445,51011
74650 - Galactose mutarotase-like
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain | 0 | Direct |
54236,47031,50729
54236 - Ubiquitin-like
47031 - Second domain of FERM
50729 - PH domain-like | 0 | Direct |
50692,54585,52540
50692 - ADC-like
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
56645,47203,47203
56645 - Acyl-CoA dehydrogenase NM domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
48726,49265,48726
48726 - Immunoglobulin
49265 - Fibronectin type III
48726 - Immunoglobulin | 0 | Direct |
49562,48371,56112
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat
56112 - Protein kinase-like (PK-like) | 0 | Direct |
56436,49854,49854
56436 - C-type lectin-like
49854 - Spermadhesin, CUB domain
49854 - Spermadhesin, CUB domain | 0 | Direct |
56112,82615,82615
56112 - Protein kinase-like (PK-like)
82615 - Polo-box domain
82615 - Polo-box domain | 0 | Direct |
50044,55550,56112
50044 - SH3-domain
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0 | Direct |
46966,46966,46966
46966 - Spectrin repeat
46966 - Spectrin repeat
46966 - Spectrin repeat | 0 | Direct |
49899,49899,49899
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
53067,53067,100920
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
57938,49493,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
46938,52087,101576
46938 - CRAL/TRIO N-terminal domain
52087 - CRAL/TRIO domain
101576 - Supernatant protein factor (SPF), C-terminal domain | 0 | Direct |
50129,51735,50129
50129 - GroES-like
51735 - NAD(P)-binding Rossmann-fold domains
50129 - GroES-like | 0 | Direct |
53738,53738,55957
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains
55957 - Phosphoglucomutase, C-terminal domain | 0 | Direct |
54897,52743,49785
54897 - Protease propeptides/inhibitors
52743 - Subtilisin-like
49785 - Galactose-binding domain-like | 0 | Direct |
50044,50044,50044
50044 - SH3-domain
50044 - SH3-domain
50044 - SH3-domain | 0 | Direct |
52440,56059,51246
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 0 | Direct |
57625,57625,57625
57625 - Invertebrate chitin-binding proteins
57625 - Invertebrate chitin-binding proteins
57625 - Invertebrate chitin-binding proteins | 0 | Direct |
90123,52540,90123
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region | 0 | Direct |
57414,57414,57414
57414 - Hairpin loop containing domain-like
57414 - Hairpin loop containing domain-like
57414 - Hairpin loop containing domain-like | 0 | Direct |
81660,56784,81665
81660 - Metal cation-transporting ATPase, ATP-binding domain N
56784 - HAD-like
81665 - Calcium ATPase, transmembrane domain M | 0.1683 | Inherited |
57424,57424,57424
57424 - LDL receptor-like module
57424 - LDL receptor-like module
57424 - LDL receptor-like module | 0.4092 | Inherited |
56436,56436,49854
56436 - C-type lectin-like
56436 - C-type lectin-like
49854 - Spermadhesin, CUB domain | 0.4242 | Inherited |
52833,52833,52833
52833 - Thioredoxin-like
52833 - Thioredoxin-like
52833 - Thioredoxin-like | 0.4947 | Inherited |
57716,57716,57716
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0.4947 | Inherited |
56968,48431,56968
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
48431 - Lipovitellin-phosvitin complex, superhelical domain
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions | 0.65 | Inherited |
57850,57850,57850
57850 - RING/U-box
57850 - RING/U-box
57850 - RING/U-box | 0.8896 | Inherited |
48726,48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin
48726 - Immunoglobulin | 0.9988 | Inherited |
48726,48726,49265
48726 - Immunoglobulin
48726 - Immunoglobulin
49265 - Fibronectin type III | 1 | Inherited |
57667,57667,57667
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers | 1 | Inherited |
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A presence/absence matrix is generated using protein domains and supradomains
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