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Worm Phenotype (WP): organism physiology variant
(show info)
Phenotype Ontology
Like Gene Ontology (GO), phenotypy ontology classifies and organizes gene-mutant/null phenotypic information from the very general at the top to more specific terms in the directed acyclic graph (DAG) by viewing an individual term as a node and its relations to parental terms (allowing for multiple parents) as directed edges. To navigate this hierarchy, we display all parental phenotypic terms to the current phenotypic term of interest ordered by their shortest distances to the current term. Also, only direct children phenotypic terms of the current phenotypic term are listed. Phenotype ontologies we have incorporated are as follows:
- Disease Ontology (DO) Ontology (DO) DO semantically integrates disease and medical vocabularies through extensive cross mapping of DO terms to MeSH, ICD, NCI thesaurus, SNOMED and OMIM.
- Human Phenotype (HP) Ontology (HP) HP captures phenotypic abnormalities that are described in OMIM, along with the corresponding disease-causing genes. It includes three complementary biological concepts: Mode_of_Inheritance (MI), ONset_and_clinical_course (ON), and Phenotypic_Abnormality (PA).
- Mouse Phenotype (MP) Ontology (MP) MP describes phenotypes of the mouse after a specific gene is genetically disrupted. Using it, Mouse Genome Informatics (MGI) provides high-coverate gene-level phenotypes for the mouse.
- Worm Phenotype (WP) Ontology (WP) WP classifies and organizes phenotype descriptions for C. elegans and other nematodes. Using it, WormBase provides primary resource for phenotype annotations for C. elegans.
- Yeast Phenotype (YP) Ontology (YP) Based on YP which is the major contributor to the Ascomycete phenotype ontology, Saccharomyces Genome Database (SGD) provides single mutant phenotypes for every gene in the yeast genome.
- Fly Phenotype (FP) Ontology (FP) FP refers to FlyBase controlled vocabulary. Specifically, a structured controlled vocabulary is used for the annotation of alleles (for their mutagen etc) in FlyBase.
- Fly Anatomy (FA) Ontology (FA) FA is a structured controlled vocabulary of the anatomy of Drosophila melanogaster, used for the description of phenotypes and where a gene is expressed.
- Zebrafish Anatomy (ZA) Ontology (ZA) ZA displays anatomical terms of the zebrafish using standard anatomical nomenclature, together with affected genes.
- Xenopus Anatomy (XA) Ontology (XA) XA represents the lineage of tissues and the timing of development for frogs (Xenopus laevis and Xenopus tropicalis). It is used to annotate Xenopus gene expression patterns and mutant and morphant phenotypes.
- Arabidopsis Plant Ontology (AP) Ontology (AP) As a major contributor to Plant Ontology which describes plant anatomical and morphological structures (AN) and growth and developmental stages (DE), the Arabidopsis Information Resource (TAIR) provides arabidopsis plant ontology annotations for the model higher plant Arabidopsis thaliana.
- Enzyme Commission (EC) Ontology (EC) Each enzyme is allocated a four-digit EC number, the first three digits of which define the reaction catalysed and the fourth of which is a unique identifier (serial number). Each enzyme is also assigned a systematic name that uniquely defines the reaction catalysed.
- DrugBank ATC (DB) Ontology (DB) In the Anatomical Therapeutic Chemical (ATC) classification system, drugs are classified in groups at five different levels according to the organ or system (1st level, anatomical main group) on which they act and their therapeutic (2nd level, therapeutic subgroup), pharmacological (3rd level, pharmacological subgroup) and chemical properties (4th level, chemical subgroup; 5th level, chemical substance). Only drugs in DrugBank are considered.
- UniProtKB KeyWords (KW) Ontology (KW) Keywords in UniProtKB are controlled vocabulary, providing a summary of the entry content and are used to index UniProtKB/Swiss-Prot entries based on 10 categories (the category "Technical term" being excluded here). Each keyword is attributed manually to UniProtKB/Swiss-Prot entries and automatically to UniProtKB/TrEMBL entries (according to specific annotation rules).
- UniProtKB UniPathway (UP) Ontology (UP) UP is a fully manually curated resource for the representation and annotation of metabolic pathways, being used as controlled vocabulary for pathway annotation in UniProtKB.
Structural Domain Phenotype Ontology and its Annotations
Structural Classification of Proteins (SCOP) classifies evolutionary-related domains into Superfamily level and Family level. Using the phenotype ontologies above, we have generated the domain-centric phenotype annotations, and further identified those phenotype terms which are the most informative to annotate SCOP domains. Promisingly, domain-centric phenotypic annotations can serve as an alternative starting point to explore genotype-phenotype relationships. We provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.
- Structural Domain Disease Ontology (DO) Ontology (SDDO) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DO.txt, and the corresponding ontology:SDDO.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Human Phenotype (HP) Ontology (SDHP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2HP.txt, and the corresponding ontology:SDHP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Mouse Phenotype (MP) Ontology (SDMP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2MP.txt, and the corresponding ontology:SDMP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Worm Phenotype (WP) Ontology (SDWP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2WP.txt, and the corresponding ontology:SDWP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Yeast Phenotype (YP) Ontology (SDYP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2YP.txt, and the corresponding ontology:SDYP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Fly Phenotype (FP) Ontology (SDFP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FP.txt, and the corresponding ontology:SDFP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Fly Anatomy (FA) Ontology (SDFA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FA.txt, and the corresponding ontology:SDFA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Zebrafish Anatomy (ZA) Ontology (SDZA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2ZA.txt, and the corresponding ontology:SDZA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Xenopus Anatomy (XA) Ontology (SDXA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2XA.txt, and the corresponding ontology:SDXA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Arabidopsis Plant Ontology (AP) Ontology (SDAP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2AP.txt, and the corresponding ontology:SDAP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Enzyme Commission (EC) Ontology (SDEC) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2EC.txt, and the corresponding ontology:SDEC.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain DrugBank ATC (DB) Ontology (SDDB) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DB.txt, and the corresponding ontology:SDDB.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain UniProtKB KeyWords (KW) Ontology (SDKW) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2KW.txt, and the corresponding ontology:SDKW.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain UniProtKB UniPathway (UP) Ontology (SDUP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2UP.txt, and the corresponding ontology:SDUP.txt) and mysql tables (Domain2PO.sql.gz).
Supra-domain Phenotype Ontology and its Annotations
Although domain-centric annotations hold great promise in describing phenotypic nature of independent domains, most domains themselves may not just work alone. In multi-domain proteins, they may be combined together to form distinct domain architectures. The recombination of the existing domains is considered as one of major driving forces for phenotypic diversificaation. As an extension, we have also generated supra-domain phenotype ontology and its annotations. Compared to domain-centric phenotype ontology and annotations (SCOP domains at the Superfamily level and Family level), this version focuses on supra-domains and individual SCOP domains ONLY at the Superfamily level. Besides, in terms of individual superfamilies, their annotations from the domain-centric version may be different from those from supra-domains version. Depending on your focus, the former should be used for the consideration of both the Superfamily level and Family level, otherwise the latter should be used if you are interested in domain combinations. Also, we provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.
- Supra-domain Domain Disease Ontology (DO) Ontology (SPDO) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DO.txt, and the corresponding ontology:SPDO.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Human Phenotype (HP) Ontology (SPHO) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2HP.txt, and the corresponding ontology:SPHO.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Mouse Phenotype (MP) Ontology (SPMP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2MP.txt, and the corresponding ontology:SPMP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Worm Phenotype (WP) Ontology (SPWP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2WP.txt, and the corresponding ontology:SPWP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Yeast Phenotype (YP) Ontology (SPYP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2YP.txt, and the corresponding ontology:SPYP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Fly Phenotype (FP) Ontology (SPFP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FP.txt, and the corresponding ontology:SPFP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Fly Anatomy (FA) Ontology (SPFA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FA.txt, and the corresponding ontology:SPFA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Zebrafish Anatomy (ZA) Ontology (SPZA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2ZA.txt, and the corresponding ontology:SPZA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Xenopus Anatomy (XA) Ontology (SPXA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2XA.txt, and the corresponding ontology:SPXA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Arabidopsis Plant Ontology (AP) Ontology (SPAP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2AP.txt, and the corresponding ontology:SPAP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Enzyme Commission (EC) Ontology (SPEC) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2EC.txt, and the corresponding ontology:SPEC.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain DrugBank ATC (DB) Ontology (SPDB) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DB.txt, and the corresponding ontology:SPDB.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain UniProtKB KeyWords (KW) Ontology (SPKW) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2KW.txt, and the corresponding ontology:SPKW.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain UniProtKB UniPathway (UP) Ontology (SPUP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2UP.txt, and the corresponding ontology:SPUP.txt) and mysql tables (SP2PO.sql.gz).
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Superfamily(show details)
Superfamily domains annotated to this WP term (Not in SDWP)
Highlighted in gray are those with FDR_all>0.001
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| Bacterial exopeptidase dimerisation domain | 0 | DIRECT |
| Sec63 N-terminal domain-like | 0 | DIRECT |
| Subtilisin-like | 0 | DIRECT |
| Cadherin-like | 0 | DIRECT |
| Lipovitellin-phosvitin complex, superhelical domain | 0 | DIRECT |
| Insulin-like | 0 | DIRECT |
| MIR domain | 0 | DIRECT |
| Chitinase insertion domain | 0 | DIRECT |
| Succinyl-CoA synthetase domains | 0 | DIRECT |
| HSP90 C-terminal domain | 0 | DIRECT |
| CRAL/TRIO N-terminal domain | 0 | DIRECT |
| PLP-binding barrel | 0 | DIRECT |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
| Citrate synthase | 0 | DIRECT |
| SAICAR synthase-like | 0 | DIRECT |
| DEATH domain | 0 | DIRECT |
| SPOC domain-like | 0 | DIRECT |
| Diaminopimelate epimerase-like | 0 | DIRECT |
| Creatinase/prolidase N-terminal domain | 0 | DIRECT |
| Hedgehog/intein (Hint) domain | 0 | DIRECT |
| Periplasmic binding protein-like II | 0 | DIRECT |
| Small-conductance potassium channel | 0 | DIRECT |
| FAD-dependent thiol oxidase | 0 | DIRECT |
| Fibrinogen C-terminal domain-like | 0 | DIRECT |
| RBP11-like subunits of RNA polymerase | 0 | DIRECT |
| Ribulose-phoshate binding barrel | 0 | DIRECT |
| Surp module (SWAP domain) | 0 | DIRECT |
| Hypothetical protein c14orf129, hspc210 | 0 | DIRECT |
| Smc hinge domain | 0 | DIRECT |
| Carboxypeptidase regulatory domain-like | 0 | DIRECT |
| CO dehydrogenase molybdoprotein N-domain-like | 0 | DIRECT |
| PurM N-terminal domain-like | 0 | DIRECT |
| Families 57/38 glycoside transferase middle domain | 0 | DIRECT |
| TK C-terminal domain-like | 0 | DIRECT |
| MgtE membrane domain-like | 0 | DIRECT |
| PK beta-barrel domain-like | 0 | DIRECT |
| Lamin A/C globular tail domain | 0 | DIRECT |
| Troponin coil-coiled subunits | 0 | DIRECT |
| Ribosomal proteins S24e, L23 and L15e | 0 | DIRECT |
| Tubulin nucleotide-binding domain-like | 0 | DIRECT |
| alpha/beta knot | 0 | DIRECT |
| Elafin-like | 0 | DIRECT |
| Formate/glycerate dehydrogenase catalytic domain-like | 0 | DIRECT |
| Phoshotransferase/anion transport protein | 0 | DIRECT |
| Acid phosphatase/Vanadium-dependent haloperoxidase | 0 | DIRECT |
| 3-carboxy-cis,cis-mucoante lactonizing enzyme | 0 | DIRECT |
| ArfGap/RecO-like zinc finger | 0 | DIRECT |
| Ribosomal protein S10 | 0 | DIRECT |
| Sec1/munc18-like (SM) proteins | 0 | DIRECT |
| Doublecortin (DC) | 0 | DIRECT |
| S-adenosylmethionine synthetase | 0 | DIRECT |
| Tim10-like | 0 | DIRECT |
| Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | DIRECT |
| HSP20-like chaperones | 0 | DIRECT |
| PEP carboxykinase-like | 0 | DIRECT |
| Actin-like ATPase domain | 0 | DIRECT |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
| PurM C-terminal domain-like | 0 | DIRECT |
| GYF domain | 0 | DIRECT |
| GroES-like | 0 | DIRECT |
| Carbon-nitrogen hydrolase | 0 | DIRECT |
| Terpenoid synthases | 0 | DIRECT |
| DNA repair protein MutS, domain III | 0 | DIRECT |
| Clc chloride channel | 0 | DIRECT |
| Tubulin C-terminal domain-like | 0 | DIRECT |
| TGS-like | 0 | DIRECT |
| R3H domain | 0 | DIRECT |
| Nop domain | 0 | DIRECT |
| DNA ligase/mRNA capping enzyme, catalytic domain | 0 | DIRECT |
| Acyl-CoA dehydrogenase NM domain-like | 0 | DIRECT |
| Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
| HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
| Cation efflux protein cytoplasmic domain-like | 0 | DIRECT |
| Phosphoenolpyruvate/pyruvate domain | 0 | DIRECT |
| Polo-box domain | 0 | DIRECT |
| Transducin (heterotrimeric G protein), gamma chain | 0 | DIRECT |
| Thiolase-like | 0 | DIRECT |
| Cullin repeat-like | 0 | DIRECT |
| WGR domain-like | 0 | DIRECT |
| PreATP-grasp domain | 0 | DIRECT |
| Carbonic anhydrase | 0 | DIRECT |
| Activating enzymes of the ubiquitin-like proteins | 0 | DIRECT |
| alpha-catenin/vinculin-like | 0 | DIRECT |
| Purine and uridine phosphorylases | 0 | DIRECT |
| SMAD MH1 domain | 0 | DIRECT |
| Integrin domains | 0 | DIRECT |
| LDH C-terminal domain-like | 0 | DIRECT |
| PABC (PABP) domain | 0 | DIRECT |
| Helical domain of Sec23/24 | 0 | DIRECT |
| ENTH/VHS domain | 0 | DIRECT |
| Chromo domain-like | 0 | DIRECT |
| JAB1/MPN domain | 0 | DIRECT |
| 14-3-3 protein | 0 | DIRECT |
| Cystatin/monellin | 0 | DIRECT |
| Complement control module/SCR domain | 0 | DIRECT |
| FtsH protease domain-like | 0 | DIRECT |
| Proton glutamate symport protein | 0 | DIRECT |
| cAMP-binding domain-like | 0 | DIRECT |
| MFPT repeat-like | 0 | DIRECT |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0 | DIRECT |
| t-snare proteins | 0 | DIRECT |
| Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
| LEM domain | 0 | DIRECT |
| Single hybrid motif | 0 | DIRECT |
| Rap/Ran-GAP | 0 | DIRECT |
| GAT-like domain | 0 | DIRECT |
| Thyroglobulin type-1 domain | 0 | DIRECT |
| AN1-like Zinc finger | 0 | DIRECT |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
| CO dehydrogenase ISP C-domain like | 0 | DIRECT |
| CBD9-like | 0 | DIRECT |
| ADP-ribosylation | 0 | DIRECT |
| dsRNA-binding domain-like | 0 | DIRECT |
| Ran binding protein zinc finger-like | 0 | DIRECT |
| Tubby C-terminal domain-like | 0 | DIRECT |
| PEBP-like | 0 | DIRECT |
| VPS9 domain | 0 | DIRECT |
| Kringle-like | 0 | DIRECT |
| Intermediate filament protein, coiled coil region | 0 | DIRECT |
| Blood coagulation inhibitor (disintegrin) | 0 | DIRECT |
| Tricorn protease domain 2 | 0 | DIRECT |
| Carbohydrate phosphatase | 0 | DIRECT |
| Profilin (actin-binding protein) | 0 | DIRECT |
| Zn-binding ribosomal proteins | 0 | DIRECT |
| L-aspartase-like | 0 | DIRECT |
| Outer arm dynein light chain 1 | 0 | DIRECT |
| Galactose oxidase, central domain | 0 | DIRECT |
| Rudiment single hybrid motif | 0 | DIRECT |
| SCP-like | 0 | DIRECT |
| DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
| ALDH-like | 0 | DIRECT |
| PEP carboxykinase N-terminal domain | 0 | DIRECT |
| Putative DNA-binding domain | 0 | DIRECT |
| Cullin homology domain | 0 | DIRECT |
| Invertebrate chitin-binding proteins | 0 | DIRECT |
| Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0 | DIRECT |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | DIRECT |
| Galactose mutarotase-like | 0 | DIRECT |
| PIN domain-like | 0 | DIRECT |
| Skp1 dimerisation domain-like | 0 | DIRECT |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | DIRECT |
| GAS2 domain-like | 0 | DIRECT |
| Arginase/deacetylase | 0 | DIRECT |
| LysM domain | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
| ThrRS/AlaRS common domain | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Spectrin repeat | 0 | DIRECT |
| Nucleoside diphosphate kinase, NDK | 0 | DIRECT |
| Mitochondrial carrier | 0 | DIRECT |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | DIRECT |
| SIS domain | 0 | DIRECT |
| Protease propeptides/inhibitors | 0 | DIRECT |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
| CAD & PB1 domains | 0 | DIRECT |
| Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | DIRECT |
| eIF4e-like | 0 | DIRECT |
| Annexin | 0 | DIRECT |
| Pentein | 0 | DIRECT |
| Thiamin diphosphate-binding fold (THDP-binding) | 0 | DIRECT |
| Aldolase | 0 | DIRECT |
| Retrovirus zinc finger-like domains | 0 | DIRECT |
| Hormone receptor domain | 0 | DIRECT |
| Chaperone J-domain | 0 | DIRECT |
| HCP-like | 0 | DIRECT |
| Restriction endonuclease-like | 0 | DIRECT |
| Molybdenum cofactor-binding domain | 0 | DIRECT |
| Ribokinase-like | 0 | DIRECT |
| Cytochrome c | 0 | DIRECT |
| PYP-like sensor domain (PAS domain) | 0 | DIRECT |
| WWE domain | 0 | DIRECT |
| Ferritin-like | 0 | DIRECT |
| Heme-dependent peroxidases | 0 | DIRECT |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
| Heme-dependent catalase-like | 0 | DIRECT |
| ARID-like | 0 | DIRECT |
| Terpenoid cyclases/Protein prenyltransferases | 0 | DIRECT |
| SAND domain-like | 0 | DIRECT |
| PGBD-like | 0 | DIRECT |
| Cation efflux protein transmembrane domain-like | 0 | DIRECT |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | DIRECT |
| YWTD domain | 0 | DIRECT |
| PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | DIRECT |
| Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
| FF domain | 0 | DIRECT |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | DIRECT |
| Aquaporin-like | 0 | DIRECT |
| F1F0 ATP synthase subunit C | 0 | DIRECT |
| Clathrin adaptor appendage domain | 0 | DIRECT |
| YbiA-like | 0 | DIRECT |
| Integrin alpha N-terminal domain | 0 | DIRECT |
| ISP domain | 0 | DIRECT |
| L30e-like | 0 | DIRECT |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | DIRECT |
| Cdc48 domain 2-like | 0 | DIRECT |
| MOSC N-terminal domain-like | 0 | DIRECT |
| Class I glutamine amidotransferase-like | 0 | DIRECT |
| Isocitrate/Isopropylmalate dehydrogenase-like | 0 | DIRECT |
| Band 7/SPFH domain | 0 | DIRECT |
| beta-lactamase/transpeptidase-like | 0 | DIRECT |
| Radical SAM enzymes | 0 | DIRECT |
| SWIB/MDM2 domain | 0 | DIRECT |
| Nucleotidyltransferase | 0 | DIRECT |
| ValRS/IleRS/LeuRS editing domain | 0 | DIRECT |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
| Domain of poly(ADP-ribose) polymerase | 0 | DIRECT |
| Pepsin inhibitor-3 | 0 | DIRECT |
| GroEL equatorial domain-like | 0 | DIRECT |
| PUA domain-like | 0 | DIRECT |
| Nucleoporin domain | 0 | DIRECT |
| Subdomain of clathrin and coatomer appendage domain | 0 | DIRECT |
| Class II aaRS ABD-related | 0 | DIRECT |
| Phosphoglucomutase, first 3 domains | 0 | DIRECT |
| Translational machinery components | 0 | DIRECT |
| PAP/OAS1 substrate-binding domain | 0 | DIRECT |
| NagB/RpiA/CoA transferase-like | 0 | DIRECT |
| Oxysterol-binding protein-like | 0 | DIRECT |
| Transducin (alpha subunit), insertion domain | 0 | DIRECT |
| PHM/PNGase F | 0 | DIRECT |
| Sec7 domain | 0 | DIRECT |
| PLC-like phosphodiesterases | 0 | DIRECT |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
| Ribosomal protein L10-like | 0 | DIRECT |
| Glutathione synthetase ATP-binding domain-like | 0 | DIRECT |
| Aminoacid dehydrogenase-like, N-terminal domain | 0 | DIRECT |
| Zn-finger domain of Sec23/24 | 0 | DIRECT |
| GroEL-intermediate domain like | 0 | DIRECT |
| Cu,Zn superoxide dismutase-like | 0 | DIRECT |
| GroEL apical domain-like | 0 | DIRECT |
| Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | DIRECT |
| 2Fe-2S ferredoxin-like | 0 | DIRECT |
| Ribosomal L27 protein-like | 0 | DIRECT |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Second domain of FERM | 0 | DIRECT |
| lambda repressor-like DNA-binding domains | 0 | DIRECT |
| Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | DIRECT |
| BEACH domain | 0 | DIRECT |
| Ribosomal protein L1 | 0 | DIRECT |
| Glycolipid transfer protein, GLTP | 0 | DIRECT |
| P-loop containing nucleoside triphosphate hydrolases | 0.000001088 | DIRECT |
| PH domain-like | 0.00004755 | DIRECT |
| Histone-fold | 0.0001226 | DIRECT |
| Periplasmic binding protein-like I | 0.01902 | INHERITED FROM: AWC odorant chemotaxis variant || chemosensory response variant || diacetyl chemotaxis variant || alkaline pH chemotaxis variant || bromide chemotaxis defective || chemotaxis variant || bromide chemotaxis variant || mechanosensation variant || carbon dioxide avoidance variant || iodide chemotaxis variant || aqueous positive chemotaxis variant || second messenger mediated signaling variant || chemical response variant || benzaldehyde chemotaxis variant || lithium chemotaxis defective || AWC odorant chemotaxis defective || aqueous chemosensory response variant || iodide chemotaxis defective || magnesium chemotaxis defective || organism environmental stimulus response variant || memory retention defective |
| TPR-like | 0.02009 | INHERITED FROM: ivermectin response variant || positive chemotaxis defective || associative learning variant || ivermectin resistant || antihelmintic response variant || light body touch resistant |
| Protein kinase-like (PK-like) | 0.02852 | INHERITED FROM: life span variant || protein phosphorylation reduced || protein expression variant || metal response variant || octanol chemotaxis defective || alkaline pH chemotaxis variant || pathogen induced gene expression variant || chemotaxis variant || mechanosensation variant || conflicting sensory integration variant || mid larval arrest || organism osmostic stress hypersensitive || colchicine resistant || anoxia resistant || second messenger mediated signaling variant || egg laying response to food variant || protein phosphorylation variant || lipid synthesis increased || chemical response variant || kinase activity reduced || protein subcellular localization variant || positive chemotaxis variant || drug induced gene expression variant || metabolic pathway variant || organism environmental stimulus response variant || aldicarb response variant |
| ARM repeat | 0.03811 | INHERITED FROM: RNAi response variant || protein expression variant || organism hypersensitive ionizing radiation || organism metabolism processing variant || sick || gene expression variant |
| PapD-like | 0.03827 | INHERITED FROM: slow growth || fat content variant || larval arrest || lipid metabolism variant || developmental growth variant || larval growth variant |
| Homeodomain-like | 0.0405 | INHERITED FROM: adrenergic receptor antagonist response variant || level of transgene expression variant || egg laying imipramine resistant || organism metabolism processing variant || carbon dioxide avoidance variant || inhibitor of serotonin uptake variant || growth rate variant || imipramine resistant || sexually dimorphic physiology variant || carbon dioxide response variant || ectopic expression transgene || protein degradation variant |
| WD40 repeat-like | 0.0475 | INHERITED FROM: protein aggregation induced behavior variant || late larval arrest || protein protein interaction variant || antimicrobial gene expression variant || organism metabolism processing variant || osmotic avoidance variant || early larval arrest || protein aggregation variant |
| PDZ domain-like | 0.05104 | INHERITED FROM: acetylcholinesterase inhibitor response variant || aldicarb response variant |
| Nucleic acid-binding proteins | 0.06463 | INHERITED FROM: nonsense mRNA accumulation || hypoxia resistant || mRNA surveillance defective || sick || hydroxyurea hypersensitive || hydroxyurea response variant |
| Acetyl-CoA synthetase-like | 0.07474 | INHERITED FROM: lipid metabolism variant |
| Cyclin-like | 0.07474 | INHERITED FROM: protein phosphorylation reduced || protein phosphorylation variant |
| "Winged helix" DNA-binding domain | 0.0779 | INHERITED FROM: paraquat hypersensitive || life span variant || protein aggregation induced behavior variant || protein expression increased || spontaneous mutation rate increased || protein protein interaction variant || chemical hypersensitive || organism metabolism processing variant || anesthetic response variant || germline transgene silencing variant || shortened life span || protein aggregation variant |
| CCCH zinc finger | 0.08284 | INHERITED FROM: RNA metabolism variant || mRNA expression ectopic || transgene expression variant || gene expression variant || ectopic expression transgene |
| Translation proteins | 0.1019 | INHERITED FROM: protein protein interaction variant || proteasome core activity variant || organism metabolism processing variant || protein phosphorylation increased || transgene expression variant || gene expression variant || protein aggregation variant || mRNA levels increased |
| HLH, helix-loop-helix DNA-binding domain | 0.124 | INHERITED FROM: pathogen resistance increased || gene expression level reduced || organism metabolism processing variant || RNA expression variant || aqueous positive chemotaxis defective || lysine chemotaxis defective || ectopic expression transgene || hypoxia response variant || fungal resistance increased |
| Nucleotide cyclase | 0.124 | INHERITED FROM: AWC odorant chemotaxis variant || chemosensory response variant || cation positive chemotaxis defective || diacetyl chemotaxis variant || alkaline pH chemotaxis variant || bromide chemotaxis defective || chemotaxis variant || bromide chemotaxis variant || osmotic avoidance variant || iodide chemotaxis variant || anion positive chemotaxis defective || anion positive chemotaxis variant || second messenger mediated signaling variant || cation positive chemotaxis variant || lithium chemotaxis defective || AWC odorant chemotaxis defective || positive chemotaxis variant || carbon dioxide response variant || iodide chemotaxis defective || magnesium chemotaxis defective || organism environmental stimulus response variant |
| SMAD/FHA domain | 0.125 | INHERITED FROM: fat content reduced || aldicarb response variant |
| Calcium ATPase, transmembrane domain M | 0.1381 | INHERITED FROM: nicotine hypersensitive || lipid composition variant || organism environmental stimulus response variant |
| Ankyrin repeat | 0.1397 | INHERITED FROM: chemosensory response variant || octanol chemotaxis defective || chemotaxis variant || mechanosensation variant || organism heat response variant || octanol chemotaxis variant || odorant negative chemotaxis defective |
| Metal cation-transporting ATPase, ATP-binding domain N | 0.1532 | INHERITED FROM: nicotine hypersensitive || lipid composition variant || organism environmental stimulus response variant |
| Regulator of G-protein signaling, RGS | 0.1532 | INHERITED FROM: chemotaxis variant || mechanosensation variant || negative chemotaxis variant |
| Cytochrome P450 | 0.1586 | INHERITED FROM: metal response variant || metabolite content decreased || cadmium response variant |
| SH3-domain | 0.1612 | INHERITED FROM: protein expression variant || protein expression reduced || aldicarb response variant |
| E set domains | 0.1661 | INHERITED FROM: paraquat hypersensitive |
| Calcium ATPase, transduction domain A | 0.1694 | INHERITED FROM: nicotine hypersensitive || organism environmental stimulus response variant |
| Acid proteases | 0.1694 | INHERITED FROM: protein protein interaction variant || organism metabolism processing variant || osmotic integrity variant || transgene subcellular localization variant || transgene expression variant || gene expression variant || protein aggregation variant || hypoosmotic shock hypersensitive || protein interaction variant |
| EGF/Laminin | 0.1798 | INHERITED FROM: octanol chemotaxis defective || negative chemotaxis variant || octanol chemotaxis variant || odorant negative chemotaxis defective |
| Cysteine-rich domain | 0.1862 | INHERITED FROM: antimicrobial gene expression variant || organism metabolism processing variant || bacterially unswollen || odorant positive chemotaxis variant || odorant chemosensory response variant || protein subcellular localization variant || acetylcholinesterase inhibitor response variant || positive chemotaxis variant || drug induced gene expression variant || organism pathogen response variant || aldicarb response variant |
| Quinoprotein alcohol dehydrogenase-like | 0.1874 | INHERITED FROM: drug response variant || mid larval arrest || L2 arrest || hypoxia response variant || protein degradation variant || mRNA levels increased |
| Multidrug efflux transporter AcrB transmembrane domain | 0.2016 | INHERITED FROM: positive chemotaxis defective || embryo osmotic integrity defective early emb || egg integrity defective early emb || odorant chemosensory response variant || odorant positive chemotaxis defective |
| DBL homology domain (DH-domain) | 0.2071 | INHERITED FROM: pathogen resistance increased || bacterially unswollen || organism pathogen response variant || organism environmental stimulus response variant || aldicarb response variant |
| ClpP/crotonase | 0.2071 | INHERITED FROM: level of transgene expression variant || fat content variant || lipid metabolism variant |
| HMG-box | 0.2071 | INHERITED FROM: maintenance of gene silencing variant || transgene expression variant |
| (Trans)glycosidases | 0.25 | INHERITED FROM: pathogen susceptibility increased || pathogen load variant |
| RNA-binding domain, RBD | 0.2573 | INHERITED FROM: antimicrobial gene expression variant || organism metabolism processing variant || RNA expression variant || maintenance of gene silencing variant || alternative splicing variant || RNA processing variant || sick || starvation induced apoptosis variant || innate immune response variant || no induction of antimicrobial peptide expression after infection || mRNA export variant |
| Bromodomain | 0.2783 | INHERITED FROM: acute functional tolerance to alcohol defective || anesthetic response variant || ethanol resistant || organism UV hypersensitive || sick || drug adaptation variant || anesthetic resistant || organism UV response variant |
| 6-phosphogluconate dehydrogenase C-terminal domain-like | 0.2783 | INHERITED FROM: fat content variant || lipid metabolism variant |
| UDP-Glycosyltransferase/glycogen phosphorylase | 0.2842 | INHERITED FROM: organism osmotic stress response variant |
| SNARE-like | 0.3068 | INHERITED FROM: aldicarb resistant || pattern of transgene expression variant || organism metabolism processing variant || protein metabolism variant || sick || transgene subcellular localization variant || transgene expression variant || gene expression variant || acetylcholinesterase inhibitor resistant |
| ABC transporter transmembrane region | 0.3072 | INHERITED FROM: RNAi response variant || metal response variant || cadmium response variant || colchicine hypersensitive || organism environmental stimulus response variant |
| POZ domain | 0.3118 | INHERITED FROM: protein aggregation induced behavior variant || chemical hypersensitive || L1 arrest || early larval arrest || resistant to protein aggregation induced paralysis |
| Cysteine proteinases | 0.3166 | INHERITED FROM: paraquat hypersensitive || protein protein interaction variant || pattern of transgene expression variant || organism metabolism processing variant || osmotic integrity variant || hypoosmotic shock hypersensitive || protein interaction variant |
| Lipocalins | 0.3171 | INHERITED FROM: paraquat hypersensitive || fat content variant || lipid metabolism variant || fat content increased |
| Nicotinic receptor ligand binding domain-like | 0.3449 | INHERITED FROM: nicotine resistant || drug response variant || mechanosensation variant || slowing response on food variant || DMPP response variant || sodium chloride chemotaxis variant || chemical response variant || aqueous chemosensory response variant || antihelmintic response variant || hypoosmotic shock hypersensitive || organism environmental stimulus response variant || cholinergic agonist resistant || selenium response variant |
| Ubiquitin-like | 0.3551 | INHERITED FROM: protein protein interaction variant || organism metabolism processing variant || heteroplasmy || protein aggregation variant || protein interaction variant |
| Translation proteins SH3-like domain | 0.3714 | INHERITED FROM: organism metabolism processing variant || early larval arrest || transgene expression variant || gene expression variant || protein aggregation variant |
| PX domain | 0.3714 | INHERITED FROM: protein expression variant || protein expression reduced || protein subcellular localization variant |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.3733 | INHERITED FROM: nicotine resistant || drug response variant || mechanosensation variant || slowing response on food variant || DMPP response variant || sodium chloride chemotaxis variant || chemical response variant || positive chemotaxis variant || aqueous chemosensory response variant || antihelmintic response variant || hypoosmotic shock hypersensitive || organism environmental stimulus response variant || cholinergic agonist resistant || selenium response variant |
| BRCT domain | 0.3914 | INHERITED FROM: organism ionizing radiation response variant |
| FKBP-like | 0.4056 | INHERITED FROM: protein protein interaction variant || pattern of transgene expression variant || transgene subcellular localization variant || protein aggregation variant || protein interaction variant |
| Galactose-binding domain-like | 0.4692 | INHERITED FROM: protein protein interaction variant || protein aggregation variant || protein interaction variant |
| SH2 domain | 0.4702 | INHERITED FROM: protein expression variant || protein expression reduced || level of protein expression variant |
| Class II aaRS and biotin synthetases | 0.4769 | INHERITED FROM: organism metabolism processing variant || hypoxia resistant || transgene expression variant || gene expression variant || oxygen response variant || hypoxia response variant || organism environmental stimulus response variant |
| RNI-like | 0.4832 | INHERITED FROM: resistant to protein aggregation induced paralysis |
| DHS-like NAD/FAD-binding domain | 0.4905 | INHERITED FROM: protein modification variant || protein acetylation variant |
| Myosin rod fragments | 0.4905 | INHERITED FROM: drug resistant |
| Hect, E3 ligase catalytic domain | 0.4905 | INHERITED FROM: protein aggregation induced behavior variant || protein protein interaction variant || pattern of transgene expression variant || organism metabolism processing variant || transgene subcellular localization variant || transgene expression variant || gene expression variant || protein aggregation variant || protein interaction variant |
| FYVE/PHD zinc finger | 0.4905 | INHERITED FROM: protein methylation variant || protein modification variant || organism UV hypersensitive || ectopic expression transgene || organism UV response variant |
| PRTase-like | 0.4905 | INHERITED FROM: Fluorouracil resistant || drug resistant |
| Voltage-gated potassium channels | 0.4979 | INHERITED FROM: adrenergic receptor antagonist response variant || serotonin resistant || mechanosensation variant || positive chemotaxis defective || serotonin response variant || protein metabolism variant || growth rate variant || protein degradation variant |
| Calpain large subunit, middle domain (domain III) | 0.5391 | INHERITED FROM: protein metabolism variant || metabolic pathway variant || protein degradation variant |
| Ferredoxin reductase-like, C-terminal NADP-linked domain | 0.5391 | INHERITED FROM: pattern protein expression variant |
| Riboflavin synthase domain-like | 0.5391 | INHERITED FROM: pattern protein expression variant |
| Sm-like ribonucleoproteins | 0.5414 | INHERITED FROM: life span variant || organism heat response variant || pattern of transgene expression variant || sick || protein subcellular localization variant || transgene expression variant || gene expression variant || unfolded protein response variant |
| WW domain | 0.5414 | INHERITED FROM: maintenance of gene silencing variant |
| Cystine-knot cytokines | 0.5414 | INHERITED FROM: nicotine response variant || levamisole response variant |
| Ribosomal protein S5 domain 2-like | 0.5543 | INHERITED FROM: early larval arrest || transgene expression variant |
| SET domain | 0.5757 | INHERITED FROM: RNAi response variant || life span variant || protein expression variant || spontaneous mutation rate increased || protein methylation variant || somatic transgene silencing variant || maintenance of gene silencing variant || histone methylation variant || protein metabolism variant || protein modification variant || ectopic expression antibody || shortened life span || dosage compensation variant || metabolic pathway variant |
| Seven-hairpin glycosidases | 0.5886 | INHERITED FROM: protein protein interaction variant || extended life span || protein aggregation variant |
| SAM/Pointed domain | 0.5895 | INHERITED FROM: aldicarb response variant |
| Nucleotidylyl transferase | 0.5895 | INHERITED FROM: organism metabolism processing variant || hypoxia resistant || transgene expression increased || oxygen response variant || hypoxia response variant || paraquat resistant || organism environmental stimulus response variant |
| UBC-like | 0.5991 | INHERITED FROM: late larval arrest || protein protein interaction variant || pattern of transgene expression variant || organism metabolism processing variant || sick || transgene subcellular localization variant || protein aggregation variant || protein interaction variant |
| FAD/NAD(P)-binding domain | 0.6063 | INHERITED FROM: life span variant || ATP levels reduced || ATP levels variant || pesticide response variant |
| FAD-linked reductases, C-terminal domain | 0.6079 | INHERITED FROM: life span variant |
| Multidrug resistance efflux transporter EmrE | 0.6079 | INHERITED FROM: pathogen resistance increased || bacterially unswollen |
| HAD-like | 0.6113 | INHERITED FROM: nicotine hypersensitive |
| Nucleotide-binding domain | 0.6446 | INHERITED FROM: extended life span |
| KA1-like | 0.6446 | INHERITED FROM: RNA expression variant |
| GST C-terminal domain-like | 0.6539 | INHERITED FROM: enzyme activity variant || organism heat hypersensitive || metal response variant || cadmium hypersensitive || enzyme activity reduced || organism electrophilic stress hypersensitive || organism environmental stimulus response variant || organism stress response variant |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0.6706 | INHERITED FROM: aging variant || RNAi response variant || protein expression variant || antimicrobial gene expression variant || chemical response variant || drug resistant || protein subcellular localization variant || growth rate variant || drug induced gene expression variant || metabolic pathway variant || nose touch variant || organism environmental stimulus response variant |
| MFS general substrate transporter | 0.7029 | INHERITED FROM: organism high sodium chloride hypersensitive |
| S15/NS1 RNA-binding domain | 0.7067 | INHERITED FROM: transgene expression increased |
| Frizzled cysteine-rich domain | 0.7067 | INHERITED FROM: transgene expression reduced || antibody staining variant |
| 4Fe-4S ferredoxins | 0.7067 | INHERITED FROM: life span variant || transgene expression increased |
| ADC-like | 0.7738 | INHERITED FROM: transgene expression reduced || protein protein interaction variant || protein metabolism variant || metabolic pathway variant || protein aggregation variant || protein interaction variant |
| MIT domain | 0.7738 | INHERITED FROM: protein protein interaction variant || protein aggregation variant || protein interaction variant |
| Fibronectin type III | 0.8094 | INHERITED FROM: metabolic pathway variant |
| Leucine zipper domain | 0.8401 | INHERITED FROM: pathogen susceptibility increased || transgene expression reduced || mRNA expression variant || level of transgene expression variant || mRNA levels reduced || pore forming toxin response variant |
| GTPase activation domain, GAP | 0.8458 | INHERITED FROM: protein expression variant |
| Clavaminate synthase-like | 0.846 | INHERITED FROM: life span variant || protein methylation variant || histone methylation variant || organism temperature response variant |
| Glucocorticoid receptor-like (DNA-binding domain) | 0.8508 | INHERITED FROM: transgene expression reduced || gene expression level reduced || gene expression level high || level of transgene expression variant || SDS sensitive dauer || dauer resistance to harsh conditions variant || fat content increased |
| EF-hand | 0.8585 | INHERITED FROM: protein aggregation variant || protein interaction variant |
| UBA-like | 0.8696 | INHERITED FROM: protein protein interaction variant || protein aggregation variant |
| alpha/beta-Hydrolases | 0.8732 | INHERITED FROM: acetylcholinesterase activity variant || fat content variant || acetylcholinesterase reduced |
| Thioredoxin-like | 0.9207 | INHERITED FROM: paraquat response variant || enzyme activity variant || organism heat hypersensitive || cadmium hypersensitive || enzyme activity reduced || organism electrophilic stress hypersensitive || organism environmental stimulus response variant || organism stress response variant |
| DNA/RNA polymerases | 0.9306 | INHERITED FROM: DNA metabolism variant || DNA repair variant |
| p53-like transcription factors | 0.9348 | INHERITED FROM: gene expression level reduced || ectopic expression transgene |
| Ribonuclease PH domain 2-like | 0.9463 | INHERITED FROM: early larval arrest |
| Immunoglobulin | 0.9546 | INHERITED FROM: growth rate variant || protein degradation variant || aldicarb response variant |
| Ribonuclease H-like | 0.9696 | INHERITED FROM: RNAi response variant || somatic transgene silencing variant || RNA expression variant || maintenance of gene silencing variant || 21U RNA expression variant || RNAi enhanced || siRNA expression variant |
| PAZ domain | 0.9808 | INHERITED FROM: RNAi response variant || somatic transgene silencing variant || RNA expression variant || maintenance of gene silencing variant || 21U RNA expression variant || RNAi enhanced || siRNA expression variant || mRNA levels increased |
| Eukaryotic type KH-domain (KH-domain type I) | 0.9891 | INHERITED FROM: RNA expression variant |
| Ligand-binding domain in the NO signalling and Golgi transport | 0.9952 | INHERITED FROM: carbon dioxide avoidance variant || carbon dioxide response variant |
| Cyclophilin-like | 0.9966 | INHERITED FROM: protein protein interaction variant || pattern of transgene expression variant || transgene subcellular localization variant || transgene expression variant || gene expression variant || protein aggregation variant || protein interaction variant |
| CoA-dependent acyltransferases | 0.9966 | INHERITED FROM: lipid metabolism variant |
| Snake toxin-like | 1 | INHERITED FROM: fat content reduced |
| beta-beta-alpha zinc fingers | 1 | INHERITED FROM: egg laying imipramine resistant || egg laying serotonin resistant || organism metabolism processing variant || inhibitor of serotonin uptake variant || imipramine resistant |
| Bet v1-like | 1 | INHERITED FROM: growth rate variant |
| Family A G protein-coupled receptor-like | 1 | INHERITED FROM: male tail curling serotonin variant || locomotion rate serotonin variant || serotonin induced fat reduction variant || serotonin induced pumping variant |
| Saposin | 1 | INHERITED FROM: transgene expression reduced || increased pathogen survival || level of transgene expression variant || pathogen load variant |
| B-box zinc-binding domain | 1 | INHERITED FROM: protein protein interaction variant || organism metabolism processing variant || transgene subcellular localization variant || transgene expression variant || gene expression variant || protein aggregation variant || protein interaction variant |
| RING/U-box | 1 | INHERITED FROM: protein protein interaction variant || pattern of transgene expression variant || organism metabolism processing variant || transgene subcellular localization variant || transgene expression variant || gene expression variant || protein aggregation variant || protein interaction variant |
| Nuclear receptor ligand-binding domain | 1 | INHERITED FROM: transgene expression reduced || gene expression level reduced || gene expression level high || level of transgene expression variant || SDS sensitive dauer || dauer resistance to harsh conditions variant || lipid metabolism variant || fat content increased |
| F-box domain | 1 | INHERITED FROM: resistant to protein aggregation induced paralysis |
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| Bacterial exopeptidase dimerisation domain | 0 | Direct |
| Sec63 N-terminal domain-like | 0 | Direct |
| Subtilisin-like | 0 | Direct |
| Cadherin-like | 0 | Direct |
| Lipovitellin-phosvitin complex, superhelical domain | 0 | Direct |
| Insulin-like | 0 | Direct |
| MIR domain | 0 | Direct |
| Chitinase insertion domain | 0 | Direct |
| Succinyl-CoA synthetase domains | 0 | Direct |
| HSP90 C-terminal domain | 0 | Direct |
| CRAL/TRIO N-terminal domain | 0 | Direct |
| PLP-binding barrel | 0 | Direct |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
| Citrate synthase | 0 | Direct |
| SAICAR synthase-like | 0 | Direct |
| DEATH domain | 0 | Direct |
| SPOC domain-like | 0 | Direct |
| Diaminopimelate epimerase-like | 0 | Direct |
| Creatinase/prolidase N-terminal domain | 0 | Direct |
| Hedgehog/intein (Hint) domain | 0 | Direct |
| Periplasmic binding protein-like II | 0 | Direct |
| Small-conductance potassium channel | 0 | Direct |
| FAD-dependent thiol oxidase | 0 | Direct |
| Fibrinogen C-terminal domain-like | 0 | Direct |
| RBP11-like subunits of RNA polymerase | 0 | Direct |
| Ribulose-phoshate binding barrel | 0 | Direct |
| Surp module (SWAP domain) | 0 | Direct |
| Hypothetical protein c14orf129, hspc210 | 0 | Direct |
| Smc hinge domain | 0 | Direct |
| Carboxypeptidase regulatory domain-like | 0 | Direct |
| CO dehydrogenase molybdoprotein N-domain-like | 0 | Direct |
| PurM N-terminal domain-like | 0 | Direct |
| Families 57/38 glycoside transferase middle domain | 0 | Direct |
| TK C-terminal domain-like | 0 | Direct |
| MgtE membrane domain-like | 0 | Direct |
| PK beta-barrel domain-like | 0 | Direct |
| Lamin A/C globular tail domain | 0 | Direct |
| Troponin coil-coiled subunits | 0 | Direct |
| Ribosomal proteins S24e, L23 and L15e | 0 | Direct |
| Tubulin nucleotide-binding domain-like | 0 | Direct |
| alpha/beta knot | 0 | Direct |
| Elafin-like | 0 | Direct |
| Formate/glycerate dehydrogenase catalytic domain-like | 0 | Direct |
| Phoshotransferase/anion transport protein | 0 | Direct |
| Acid phosphatase/Vanadium-dependent haloperoxidase | 0 | Direct |
| 3-carboxy-cis,cis-mucoante lactonizing enzyme | 0 | Direct |
| ArfGap/RecO-like zinc finger | 0 | Direct |
| Ribosomal protein S10 | 0 | Direct |
| Sec1/munc18-like (SM) proteins | 0 | Direct |
| Doublecortin (DC) | 0 | Direct |
| S-adenosylmethionine synthetase | 0 | Direct |
| Tim10-like | 0 | Direct |
| Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | Direct |
| HSP20-like chaperones | 0 | Direct |
| PEP carboxykinase-like | 0 | Direct |
| Actin-like ATPase domain | 0 | Direct |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
| PurM C-terminal domain-like | 0 | Direct |
| GYF domain | 0 | Direct |
| GroES-like | 0 | Direct |
| Carbon-nitrogen hydrolase | 0 | Direct |
| Terpenoid synthases | 0 | Direct |
| DNA repair protein MutS, domain III | 0 | Direct |
| Clc chloride channel | 0 | Direct |
| Tubulin C-terminal domain-like | 0 | Direct |
| TGS-like | 0 | Direct |
| R3H domain | 0 | Direct |
| Nop domain | 0 | Direct |
| DNA ligase/mRNA capping enzyme, catalytic domain | 0 | Direct |
| Acyl-CoA dehydrogenase NM domain-like | 0 | Direct |
| Composite domain of metallo-dependent hydrolases | 0 | Direct |
| HSP40/DnaJ peptide-binding domain | 0 | Direct |
| Cation efflux protein cytoplasmic domain-like | 0 | Direct |
| Phosphoenolpyruvate/pyruvate domain | 0 | Direct |
| Polo-box domain | 0 | Direct |
| Transducin (heterotrimeric G protein), gamma chain | 0 | Direct |
| Thiolase-like | 0 | Direct |
| Cullin repeat-like | 0 | Direct |
| WGR domain-like | 0 | Direct |
| PreATP-grasp domain | 0 | Direct |
| Carbonic anhydrase | 0 | Direct |
| Activating enzymes of the ubiquitin-like proteins | 0 | Direct |
| alpha-catenin/vinculin-like | 0 | Direct |
| Purine and uridine phosphorylases | 0 | Direct |
| SMAD MH1 domain | 0 | Direct |
| Integrin domains | 0 | Direct |
| LDH C-terminal domain-like | 0 | Direct |
| PABC (PABP) domain | 0 | Direct |
| Helical domain of Sec23/24 | 0 | Direct |
| ENTH/VHS domain | 0 | Direct |
| Chromo domain-like | 0 | Direct |
| JAB1/MPN domain | 0 | Direct |
| 14-3-3 protein | 0 | Direct |
| Cystatin/monellin | 0 | Direct |
| Complement control module/SCR domain | 0 | Direct |
| FtsH protease domain-like | 0 | Direct |
| Proton glutamate symport protein | 0 | Direct |
| cAMP-binding domain-like | 0 | Direct |
| MFPT repeat-like | 0 | Direct |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0 | Direct |
| t-snare proteins | 0 | Direct |
| Phosphoglucomutase, C-terminal domain | 0 | Direct |
| LEM domain | 0 | Direct |
| Single hybrid motif | 0 | Direct |
| Rap/Ran-GAP | 0 | Direct |
| GAT-like domain | 0 | Direct |
| Thyroglobulin type-1 domain | 0 | Direct |
| AN1-like Zinc finger | 0 | Direct |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
| CO dehydrogenase ISP C-domain like | 0 | Direct |
| CBD9-like | 0 | Direct |
| ADP-ribosylation | 0 | Direct |
| dsRNA-binding domain-like | 0 | Direct |
| Ran binding protein zinc finger-like | 0 | Direct |
| Tubby C-terminal domain-like | 0 | Direct |
| PEBP-like | 0 | Direct |
| VPS9 domain | 0 | Direct |
| Kringle-like | 0 | Direct |
| Intermediate filament protein, coiled coil region | 0 | Direct |
| Blood coagulation inhibitor (disintegrin) | 0 | Direct |
| Tricorn protease domain 2 | 0 | Direct |
| Carbohydrate phosphatase | 0 | Direct |
| Profilin (actin-binding protein) | 0 | Direct |
| Zn-binding ribosomal proteins | 0 | Direct |
| L-aspartase-like | 0 | Direct |
| Outer arm dynein light chain 1 | 0 | Direct |
| Galactose oxidase, central domain | 0 | Direct |
| Rudiment single hybrid motif | 0 | Direct |
| SCP-like | 0 | Direct |
| DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
| ALDH-like | 0 | Direct |
| PEP carboxykinase N-terminal domain | 0 | Direct |
| Putative DNA-binding domain | 0 | Direct |
| Cullin homology domain | 0 | Direct |
| Invertebrate chitin-binding proteins | 0 | Direct |
| Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0 | Direct |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | Direct |
| Galactose mutarotase-like | 0 | Direct |
| PIN domain-like | 0 | Direct |
| Skp1 dimerisation domain-like | 0 | Direct |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | Direct |
| GAS2 domain-like | 0 | Direct |
| Arginase/deacetylase | 0 | Direct |
| LysM domain | 0 | Direct |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
| ThrRS/AlaRS common domain | 0 | Direct |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Spectrin repeat | 0 | Direct |
| Nucleoside diphosphate kinase, NDK | 0 | Direct |
| Mitochondrial carrier | 0 | Direct |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | Direct |
| SIS domain | 0 | Direct |
| Protease propeptides/inhibitors | 0 | Direct |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
| CAD & PB1 domains | 0 | Direct |
| Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | Direct |
| eIF4e-like | 0 | Direct |
| Annexin | 0 | Direct |
| Pentein | 0 | Direct |
| Thiamin diphosphate-binding fold (THDP-binding) | 0 | Direct |
| Aldolase | 0 | Direct |
| Retrovirus zinc finger-like domains | 0 | Direct |
| Hormone receptor domain | 0 | Direct |
| Chaperone J-domain | 0 | Direct |
| HCP-like | 0 | Direct |
| Restriction endonuclease-like | 0 | Direct |
| Molybdenum cofactor-binding domain | 0 | Direct |
| Ribokinase-like | 0 | Direct |
| Cytochrome c | 0 | Direct |
| PYP-like sensor domain (PAS domain) | 0 | Direct |
| WWE domain | 0 | Direct |
| Ferritin-like | 0 | Direct |
| Heme-dependent peroxidases | 0 | Direct |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | Direct |
| Heme-dependent catalase-like | 0 | Direct |
| ARID-like | 0 | Direct |
| Terpenoid cyclases/Protein prenyltransferases | 0 | Direct |
| SAND domain-like | 0 | Direct |
| PGBD-like | 0 | Direct |
| Cation efflux protein transmembrane domain-like | 0 | Direct |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | Direct |
| YWTD domain | 0 | Direct |
| PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | Direct |
| Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
| FF domain | 0 | Direct |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | Direct |
| Aquaporin-like | 0 | Direct |
| F1F0 ATP synthase subunit C | 0 | Direct |
| Clathrin adaptor appendage domain | 0 | Direct |
| YbiA-like | 0 | Direct |
| Integrin alpha N-terminal domain | 0 | Direct |
| ISP domain | 0 | Direct |
| L30e-like | 0 | Direct |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | Direct |
| Cdc48 domain 2-like | 0 | Direct |
| MOSC N-terminal domain-like | 0 | Direct |
| Class I glutamine amidotransferase-like | 0 | Direct |
| Isocitrate/Isopropylmalate dehydrogenase-like | 0 | Direct |
| Band 7/SPFH domain | 0 | Direct |
| beta-lactamase/transpeptidase-like | 0 | Direct |
| Radical SAM enzymes | 0 | Direct |
| SWIB/MDM2 domain | 0 | Direct |
| Nucleotidyltransferase | 0 | Direct |
| ValRS/IleRS/LeuRS editing domain | 0 | Direct |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
| Domain of poly(ADP-ribose) polymerase | 0 | Direct |
| Pepsin inhibitor-3 | 0 | Direct |
| GroEL equatorial domain-like | 0 | Direct |
| PUA domain-like | 0 | Direct |
| Nucleoporin domain | 0 | Direct |
| Subdomain of clathrin and coatomer appendage domain | 0 | Direct |
| Class II aaRS ABD-related | 0 | Direct |
| Phosphoglucomutase, first 3 domains | 0 | Direct |
| Translational machinery components | 0 | Direct |
| PAP/OAS1 substrate-binding domain | 0 | Direct |
| NagB/RpiA/CoA transferase-like | 0 | Direct |
| Oxysterol-binding protein-like | 0 | Direct |
| Transducin (alpha subunit), insertion domain | 0 | Direct |
| PHM/PNGase F | 0 | Direct |
| Sec7 domain | 0 | Direct |
| PLC-like phosphodiesterases | 0 | Direct |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
| Ribosomal protein L10-like | 0 | Direct |
| Glutathione synthetase ATP-binding domain-like | 0 | Direct |
| Aminoacid dehydrogenase-like, N-terminal domain | 0 | Direct |
| Zn-finger domain of Sec23/24 | 0 | Direct |
| GroEL-intermediate domain like | 0 | Direct |
| Cu,Zn superoxide dismutase-like | 0 | Direct |
| GroEL apical domain-like | 0 | Direct |
| Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | Direct |
| 2Fe-2S ferredoxin-like | 0 | Direct |
| Ribosomal L27 protein-like | 0 | Direct |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Second domain of FERM | 0 | Direct |
| lambda repressor-like DNA-binding domains | 0 | Direct |
| Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | Direct |
| BEACH domain | 0 | Direct |
| Ribosomal protein L1 | 0 | Direct |
| Glycolipid transfer protein, GLTP | 0 | Direct |
| P-loop containing nucleoside triphosphate hydrolases | 0.000001088 | Direct |
| PH domain-like | 0.00004755 | Direct |
| Histone-fold | 0.0001226 | Direct |
| Periplasmic binding protein-like I | 0.01902 | Inherited |
| TPR-like | 0.02009 | Inherited |
| Protein kinase-like (PK-like) | 0.02852 | Inherited |
| ARM repeat | 0.03811 | Inherited |
| PapD-like | 0.03827 | Inherited |
| Homeodomain-like | 0.0405 | Inherited |
| WD40 repeat-like | 0.0475 | Inherited |
| PDZ domain-like | 0.05104 | Inherited |
| Nucleic acid-binding proteins | 0.06463 | Inherited |
| Acetyl-CoA synthetase-like | 0.07474 | Inherited |
| Cyclin-like | 0.07474 | Inherited |
| "Winged helix" DNA-binding domain | 0.0779 | Inherited |
| CCCH zinc finger | 0.08284 | Inherited |
| Translation proteins | 0.1019 | Inherited |
| HLH, helix-loop-helix DNA-binding domain | 0.124 | Inherited |
| Nucleotide cyclase | 0.124 | Inherited |
| SMAD/FHA domain | 0.125 | Inherited |
| Calcium ATPase, transmembrane domain M | 0.1381 | Inherited |
| Ankyrin repeat | 0.1397 | Inherited |
| Metal cation-transporting ATPase, ATP-binding domain N | 0.1532 | Inherited |
| Regulator of G-protein signaling, RGS | 0.1532 | Inherited |
| Cytochrome P450 | 0.1586 | Inherited |
| SH3-domain | 0.1612 | Inherited |
| E set domains | 0.1661 | Inherited |
| Calcium ATPase, transduction domain A | 0.1694 | Inherited |
| Acid proteases | 0.1694 | Inherited |
| EGF/Laminin | 0.1798 | Inherited |
| Cysteine-rich domain | 0.1862 | Inherited |
| Quinoprotein alcohol dehydrogenase-like | 0.1874 | Inherited |
| Multidrug efflux transporter AcrB transmembrane domain | 0.2016 | Inherited |
| DBL homology domain (DH-domain) | 0.2071 | Inherited |
| ClpP/crotonase | 0.2071 | Inherited |
| HMG-box | 0.2071 | Inherited |
| (Trans)glycosidases | 0.25 | Inherited |
| RNA-binding domain, RBD | 0.2573 | Inherited |
| Bromodomain | 0.2783 | Inherited |
| 6-phosphogluconate dehydrogenase C-terminal domain-like | 0.2783 | Inherited |
| UDP-Glycosyltransferase/glycogen phosphorylase | 0.2842 | Inherited |
| SNARE-like | 0.3068 | Inherited |
| ABC transporter transmembrane region | 0.3072 | Inherited |
| POZ domain | 0.3118 | Inherited |
| Cysteine proteinases | 0.3166 | Inherited |
| Lipocalins | 0.3171 | Inherited |
| Nicotinic receptor ligand binding domain-like | 0.3449 | Inherited |
| Ubiquitin-like | 0.3551 | Inherited |
| Translation proteins SH3-like domain | 0.3714 | Inherited |
| PX domain | 0.3714 | Inherited |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.3733 | Inherited |
| BRCT domain | 0.3914 | Inherited |
| FKBP-like | 0.4056 | Inherited |
| Galactose-binding domain-like | 0.4692 | Inherited |
| SH2 domain | 0.4702 | Inherited |
| Class II aaRS and biotin synthetases | 0.4769 | Inherited |
| RNI-like | 0.4832 | Inherited |
| DHS-like NAD/FAD-binding domain | 0.4905 | Inherited |
| Myosin rod fragments | 0.4905 | Inherited |
| Hect, E3 ligase catalytic domain | 0.4905 | Inherited |
| FYVE/PHD zinc finger | 0.4905 | Inherited |
| PRTase-like | 0.4905 | Inherited |
| Voltage-gated potassium channels | 0.4979 | Inherited |
| Calpain large subunit, middle domain (domain III) | 0.5391 | Inherited |
| Ferredoxin reductase-like, C-terminal NADP-linked domain | 0.5391 | Inherited |
| Riboflavin synthase domain-like | 0.5391 | Inherited |
| Sm-like ribonucleoproteins | 0.5414 | Inherited |
| WW domain | 0.5414 | Inherited |
| Cystine-knot cytokines | 0.5414 | Inherited |
| Ribosomal protein S5 domain 2-like | 0.5543 | Inherited |
| SET domain | 0.5757 | Inherited |
| Seven-hairpin glycosidases | 0.5886 | Inherited |
| SAM/Pointed domain | 0.5895 | Inherited |
| Nucleotidylyl transferase | 0.5895 | Inherited |
| UBC-like | 0.5991 | Inherited |
| FAD/NAD(P)-binding domain | 0.6063 | Inherited |
| FAD-linked reductases, C-terminal domain | 0.6079 | Inherited |
| Multidrug resistance efflux transporter EmrE | 0.6079 | Inherited |
| HAD-like | 0.6113 | Inherited |
| Nucleotide-binding domain | 0.6446 | Inherited |
| KA1-like | 0.6446 | Inherited |
| GST C-terminal domain-like | 0.6539 | Inherited |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0.6706 | Inherited |
| MFS general substrate transporter | 0.7029 | Inherited |
| S15/NS1 RNA-binding domain | 0.7067 | Inherited |
| Frizzled cysteine-rich domain | 0.7067 | Inherited |
| 4Fe-4S ferredoxins | 0.7067 | Inherited |
| ADC-like | 0.7738 | Inherited |
| MIT domain | 0.7738 | Inherited |
| Fibronectin type III | 0.8094 | Inherited |
| Leucine zipper domain | 0.8401 | Inherited |
| GTPase activation domain, GAP | 0.8458 | Inherited |
| Clavaminate synthase-like | 0.846 | Inherited |
| Glucocorticoid receptor-like (DNA-binding domain) | 0.8508 | Inherited |
| EF-hand | 0.8585 | Inherited |
| UBA-like | 0.8696 | Inherited |
| alpha/beta-Hydrolases | 0.8732 | Inherited |
| Thioredoxin-like | 0.9207 | Inherited |
| DNA/RNA polymerases | 0.9306 | Inherited |
| p53-like transcription factors | 0.9348 | Inherited |
| Ribonuclease PH domain 2-like | 0.9463 | Inherited |
| Immunoglobulin | 0.9546 | Inherited |
| Ribonuclease H-like | 0.9696 | Inherited |
| PAZ domain | 0.9808 | Inherited |
| Eukaryotic type KH-domain (KH-domain type I) | 0.9891 | Inherited |
| Ligand-binding domain in the NO signalling and Golgi transport | 0.9952 | Inherited |
| Cyclophilin-like | 0.9966 | Inherited |
| CoA-dependent acyltransferases | 0.9966 | Inherited |
| Snake toxin-like | 1 | Inherited |
| beta-beta-alpha zinc fingers | 1 | Inherited |
| Bet v1-like | 1 | Inherited |
| Family A G protein-coupled receptor-like | 1 | Inherited |
| Saposin | 1 | Inherited |
| B-box zinc-binding domain | 1 | Inherited |
| RING/U-box | 1 | Inherited |
| Nuclear receptor ligand-binding domain | 1 | Inherited |
| F-box domain | 1 | Inherited |
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Family(show details)
Family domains annotated to this WP term (Not in SDWP)
Highlighted in gray are those with FDR_all>0.001
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| Carbonic anhydrase | 0 | DIRECT |
| Myeloperoxidase-like | 0 | DIRECT |
| Polo-box duplicated region | 0 | DIRECT |
| Peptidylglycine alpha-hydroxylating monooxygenase, PHM | 0 | DIRECT |
| alpha-mannosidase, domain 2 | 0 | DIRECT |
| alpha-mannosidase, C-terminal domain | 0 | DIRECT |
| Second domain of FERM | 0 | DIRECT |
| Actin/HSP70 | 0 | DIRECT |
| Calcium ATPase, transmembrane domain M | 0 | DIRECT |
| Helical domain of Sec23/24 | 0 | DIRECT |
| YbiA-like | 0 | DIRECT |
| MOSC N-terminal domain-like | 0 | DIRECT |
| L30e/L7ae ribosomal proteins | 0 | DIRECT |
| MIR domain | 0 | DIRECT |
| XPF/Rad1/Mus81 nuclease | 0 | DIRECT |
| Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain | 0 | DIRECT |
| Third domain of FERM | 0 | DIRECT |
| Adenosine/AMP deaminase | 0 | DIRECT |
| LEM domain | 0 | DIRECT |
| Bactericidal permeability-increasing protein, BPI | 0 | DIRECT |
| Sec63 N-terminal domain | 0 | DIRECT |
| t-snare proteins | 0 | DIRECT |
| Pancreatic carboxypeptidases | 0 | DIRECT |
| HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
| Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | DIRECT |
| D-aminoacid oxidase-like | 0 | DIRECT |
| Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | DIRECT |
| CoA transferase alpha subunit-like | 0 | DIRECT |
| Cell cycle control phosphatase, catalytic domain | 0 | DIRECT |
| SCF ubiquitin ligase complex WHB domain | 0 | DIRECT |
| PUA domain | 0 | DIRECT |
| Ubiquitin carboxyl-terminal hydrolase UCH-L | 0 | DIRECT |
| PhzC/PhzF-like | 0 | DIRECT |
| BEACH domain | 0 | DIRECT |
| Transducin (alpha subunit), insertion domain | 0 | DIRECT |
| Cullin homology domain | 0 | DIRECT |
| Adenain-like | 0 | DIRECT |
| Zn-finger domain of Sec23/24 | 0 | DIRECT |
| Arginine methyltransferase | 0 | DIRECT |
| YWTD domain | 0 | DIRECT |
| CO dehydrogenase flavoprotein N-terminal domain-like | 0 | DIRECT |
| YihX-like | 0 | DIRECT |
| Proprotein convertase P-domain | 0 | DIRECT |
| PDI-like | 0 | DIRECT |
| alpha-Amylases, C-terminal beta-sheet domain | 0 | DIRECT |
| Poly(A) polymerase, PAP, middle domain | 0 | DIRECT |
| Phosphatidylethanolamine binding protein | 0 | DIRECT |
| Medium chain acyl-CoA dehydrogenase-like, C-terminal domain | 0 | DIRECT |
| Pleckstrin-homology domain (PH domain) | 0 | DIRECT |
| MFPT repeat | 0 | DIRECT |
| FF domain | 0 | DIRECT |
| Linker histone H1/H5 | 0 | DIRECT |
| Skp1 dimerisation domain-like | 0 | DIRECT |
| Phosphoglucomutase, first 3 domains | 0 | DIRECT |
| Quinoprotein alcohol dehydrogenase-like | 0 | DIRECT |
| Complement control module/SCR domain | 0 | DIRECT |
| Hypothetical protein c14orf129, hspc210 | 0 | DIRECT |
| Smc hinge domain | 0 | DIRECT |
| Choline kinase | 0 | DIRECT |
| Glycolipid transfer protein, GLTP | 0 | DIRECT |
| Acireductone dioxygenase | 0 | DIRECT |
| Formate/glycerate dehydrogenases, NAD-domain | 0 | DIRECT |
| GAS2 domain | 0 | DIRECT |
| Biotinyl/lipoyl-carrier proteins and domains | 0 | DIRECT |
| Trunk domain of Sec23/24 | 0 | DIRECT |
| Thiolase-related | 0 | DIRECT |
| Protein prenyltransferases | 0 | DIRECT |
| Lactate & malate dehydrogenases, C-terminal domain | 0 | DIRECT |
| PABC (PABP) domain | 0 | DIRECT |
| HEAT repeat | 0 | DIRECT |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
| Clathrin coat assembly domain | 0 | DIRECT |
| HSP20 | 0 | DIRECT |
| Group II chaperonin (CCT, TRIC), intermediate domain | 0 | DIRECT |
| Succinyl-CoA synthetase domains | 0 | DIRECT |
| L-aminoacid/polyamine oxidase | 0 | DIRECT |
| Acylamino-acid-releasing enzyme, C-terminal donain | 0 | DIRECT |
| Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain | 0 | DIRECT |
| Rap/Ran-GAP | 0 | DIRECT |
| FHA domain | 0 | DIRECT |
| Glycerophosphoryl diester phosphodiesterase | 0 | DIRECT |
| Purine and uridine phosphorylases | 0 | DIRECT |
| First domain of FERM | 0 | DIRECT |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| AN1-like Zinc finger | 0 | DIRECT |
| Pepsin inhibitor-3 | 0 | DIRECT |
| DNA replication initiator (cdc21/cdc54) N-terminal domain | 0 | DIRECT |
| Transducin (heterotrimeric G protein), gamma chain | 0 | DIRECT |
| Poly(A) polymerase, PAP, C-terminal domain | 0 | DIRECT |
| DNA gyrase/MutL, N-terminal domain | 0 | DIRECT |
| UDP-glucose pyrophosphorylase | 0 | DIRECT |
| Cyclin | 0 | DIRECT |
| ValRS/IleRS/LeuRS editing domain | 0 | DIRECT |
| CUT domain | 0 | DIRECT |
| ets domain | 0 | DIRECT |
| PEP carboxykinase N-terminal domain | 0 | DIRECT |
| Retrovirus zinc finger-like domains | 0 | DIRECT |
| Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta | 0 | DIRECT |
| Methionine aminopeptidase, insert domain | 0 | DIRECT |
| Fibrinogen C-terminal domain-like | 0 | DIRECT |
| Annexin | 0 | DIRECT |
| Hedgehog C-terminal (Hog) autoprocessing domain | 0 | DIRECT |
| RhoGDI-like | 0 | DIRECT |
| VHS domain | 0 | DIRECT |
| 1,3-glucuronyltransferase | 0 | DIRECT |
| Histone deacetylase, HDAC | 0 | DIRECT |
| Alcohol dehydrogenase-like, N-terminal domain | 0 | DIRECT |
| Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | DIRECT |
| Type II chitinase | 0 | DIRECT |
| BC ATP-binding domain-like | 0 | DIRECT |
| Cofilin-like | 0 | DIRECT |
| acyl-CoA oxidase N-terminal domains | 0 | DIRECT |
| SAM (sterile alpha motif) domain | 0 | DIRECT |
| FtsH protease domain-like | 0 | DIRECT |
| Elafin-like | 0 | DIRECT |
| Proton glutamate symport protein | 0 | DIRECT |
| Ribosomal protein L1 | 0 | DIRECT |
| RNA-polymerase beta | 0 | DIRECT |
| Class II glutamine amidotransferases | 0 | DIRECT |
| CoA-binding domain | 0 | DIRECT |
| Pyk2-associated protein beta ARF-GAP domain | 0 | DIRECT |
| BC C-terminal domain-like | 0 | DIRECT |
| Cytoplasmic domain of inward rectifier potassium channel | 0 | DIRECT |
| Amylase, catalytic domain | 0 | DIRECT |
| Mammalian PLC | 0 | DIRECT |
| ARID domain | 0 | DIRECT |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
| GAPDH-like | 0 | DIRECT |
| SMAD domain | 0 | DIRECT |
| PurM C-terminal domain-like | 0 | DIRECT |
| Aminoacid dehydrogenase-like, C-terminal domain | 0 | DIRECT |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
| NHL repeat | 0 | DIRECT |
| Tubulin, GTPase domain | 0 | DIRECT |
| Myotubularin-like phosphatases | 0 | DIRECT |
| Aquaporin-like | 0 | DIRECT |
| Cullin repeat | 0 | DIRECT |
| Proteasome subunits | 0 | DIRECT |
| Profilin (actin-binding protein) | 0 | DIRECT |
| Reductases | 0 | DIRECT |
| PDEase | 0 | DIRECT |
| Intermediate filament protein, coiled coil region | 0 | DIRECT |
| Surp module (SWAP domain) | 0 | DIRECT |
| Spectrin repeat | 0 | DIRECT |
| Calpain large subunit, catalytic domain (domain II) | 0 | DIRECT |
| Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain | 0 | DIRECT |
| Chaperone J-domain | 0 | DIRECT |
| Phoshoinositide 3-kinase (PI3K) helical domain | 0 | DIRECT |
| CAT-like | 0 | DIRECT |
| FAD-dependent thiol oxidase | 0 | DIRECT |
| Anticodon-binding domain | 0 | DIRECT |
| Acyl-CoA thioesterase | 0 | DIRECT |
| Chromo domain | 0 | DIRECT |
| CRAL/TRIO N-terminal domain | 0 | DIRECT |
| SMAD MH1 domain | 0 | DIRECT |
| 14-3-3 protein | 0 | DIRECT |
| Heat shock protein 90, HSP90, N-terminal domain | 0 | DIRECT |
| Epoxide hydrolase | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | DIRECT |
| Lipovitellin-phosvitin complex, superhelical domain | 0 | DIRECT |
| Ribosomal protein L18 and S11 | 0 | DIRECT |
| Ngr ectodomain-like | 0 | DIRECT |
| Insulin-like | 0 | DIRECT |
| cAMP-binding domain | 0 | DIRECT |
| D-aminoacid oxidase, N-terminal domain | 0 | DIRECT |
| COMT-like | 0 | DIRECT |
| Regulator of chromosome condensation RCC1 | 0 | DIRECT |
| Serum paraoxonase/arylesterase 1, PON1 | 0 | DIRECT |
| Acyl-carrier protein (ACP) | 0 | DIRECT |
| Glycerol kinase | 0 | DIRECT |
| Tim10/DDP | 0 | DIRECT |
| Cdc48 domain 2-like | 0 | DIRECT |
| Erythroid transcription factor GATA-1 | 0 | DIRECT |
| WWE domain | 0 | DIRECT |
| alpha-mannosidase | 0 | DIRECT |
| Phoshoinositide 3-kinase (PI3K), catalytic domain | 0 | DIRECT |
| Lamin A/C globular tail domain | 0 | DIRECT |
| Dimeric isocitrate & isopropylmalate dehydrogenases | 0 | DIRECT |
| CO dehydrogenase ISP C-domain like | 0 | DIRECT |
| Sec1/munc18-like (SM) proteins | 0 | DIRECT |
| RecA protein-like (ATPase-domain) | 0 | DIRECT |
| Phosphate binding protein-like | 0 | DIRECT |
| Arfaptin, Rac-binding fragment | 0 | DIRECT |
| Hydantoinase (dihydropyrimidinase) | 0 | DIRECT |
| POU-specific domain | 0 | DIRECT |
| Glycogenin | 0 | DIRECT |
| Paired domain | 0 | DIRECT |
| Branched-chain alpha-keto acid dehydrogenase PP module | 0 | DIRECT |
| S-adenosylmethionine synthetase | 0 | DIRECT |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| ATP-dependent protease Lon (La), catalytic domain | 0 | DIRECT |
| SWIRM domain | 0 | DIRECT |
| Ferredoxin reductase FAD-binding domain-like | 0 | DIRECT |
| Citrate synthase | 0 | DIRECT |
| SWIB/MDM2 domain | 0 | DIRECT |
| PurM N-terminal domain-like | 0 | DIRECT |
| Cu,Zn superoxide dismutase-like | 0 | DIRECT |
| DNA repair protein MutS, domain III | 0 | DIRECT |
| beta 1,4 galactosyltransferase (b4GalT1) | 0 | DIRECT |
| Ran binding protein zinc finger-like | 0 | DIRECT |
| Inositol polyphosphate kinase (IPK) | 0 | DIRECT |
| Laminin G-like module | 0 | DIRECT |
| GYF domain | 0 | DIRECT |
| MutT-like | 0 | DIRECT |
| Sec63 C-terminal domain-like | 0 | DIRECT |
| Heme-dependent catalases | 0 | DIRECT |
| Pancreatic carboxypeptidase, activation domain | 0 | DIRECT |
| PaaI/YdiI-like | 0 | DIRECT |
| DPP6 catalytic domain-like | 0 | DIRECT |
| UBA domain | 0 | DIRECT |
| WGR domain | 0 | DIRECT |
| HD domain | 0 | DIRECT |
| YicI catalytic domain-like | 0 | DIRECT |
| Pumilio repeat | 0 | DIRECT |
| Translation initiation factor eIF4e | 0 | DIRECT |
| Group II chaperonin (CCT, TRIC), apical domain | 0 | DIRECT |
| Nucleoside diphosphate kinase, NDK | 0 | DIRECT |
| DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
| Bacterial exopeptidase dimerisation domain | 0 | DIRECT |
| Hormone receptor domain | 0 | DIRECT |
| Glycosyl transferases group 1 | 0 | DIRECT |
| Arylsulfatase | 0 | DIRECT |
| Single strand DNA-binding domain, SSB | 0 | DIRECT |
| Lesion bypass DNA polymerase (Y-family), catalytic domain | 0 | DIRECT |
| DNA gyrase/MutL, second domain | 0 | DIRECT |
| IF2B-like | 0 | DIRECT |
| Subtilases | 0 | DIRECT |
| Translational machinery components | 0 | DIRECT |
| 5' to 3' exonuclease catalytic domain | 0 | DIRECT |
| Group II chaperonin (CCT, TRIC), ATPase domain | 0 | DIRECT |
| RNA editing terminal uridyl transferase 2, RET2, domain 2 | 0 | DIRECT |
| Reprolysin-like | 0 | DIRECT |
| Blood coagulation inhibitor (disintegrin) | 0 | DIRECT |
| Poly(A) polymerase, PAP, N-terminal domain | 0 | DIRECT |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
| LysM domain | 0 | DIRECT |
| Integrin domains | 0 | DIRECT |
| Nop domain | 0 | DIRECT |
| DEP domain | 0 | DIRECT |
| BAR domain | 0 | DIRECT |
| Ubiquitin activating enzymes (UBA) | 0 | DIRECT |
| HAT/Suf repeat | 0 | DIRECT |
| BC N-terminal domain-like | 0 | DIRECT |
| U-box | 0 | DIRECT |
| Doublecortin (DC) | 0 | DIRECT |
| Ribokinase-like | 0 | DIRECT |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
| Filamin repeat (rod domain) | 0 | DIRECT |
| a tRNA synthase domain | 0 | DIRECT |
| Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains | 0 | DIRECT |
| Small-conductance potassium channel | 0 | DIRECT |
| HSP90 C-terminal domain | 0 | DIRECT |
| Band 7/SPFH domain | 0 | DIRECT |
| beta-Lactamase/D-ala carboxypeptidase | 0 | DIRECT |
| AMPK-beta glycogen binding domain-like | 0 | DIRECT |
| Sec7 domain | 0 | DIRECT |
| Phosphoribosyltransferases (PRTases) | 0 | DIRECT |
| LDH N-terminal domain-like | 0 | DIRECT |
| PEP carboxykinase C-terminal domain | 0 | DIRECT |
| Thyroglobulin type-1 domain | 0 | DIRECT |
| acyl-CoA oxidase C-terminal domains | 0 | DIRECT |
| Gamma-glutamyltranspeptidase-like | 0 | DIRECT |
| La domain | 0 | DIRECT |
| Nucleosome core histones | 0 | DIRECT |
| Sterol carrier protein, SCP | 0 | DIRECT |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | DIRECT |
| Branched-chain alpha-keto acid dehydrogenase Pyr module | 0 | DIRECT |
| LacY-like proton/sugar symporter | 0 | DIRECT |
| MIF4G domain-like | 0 | DIRECT |
| Cation efflux protein transmembrane domain-like | 0 | DIRECT |
| Domain of poly(ADP-ribose) polymerase | 0 | DIRECT |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
| Chitinase insertion domain | 0 | DIRECT |
| RNA-polymerase beta-prime | 0 | DIRECT |
| Cation efflux protein cytoplasmic domain-like | 0 | DIRECT |
| alpha-catenin/vinculin | 0 | DIRECT |
| PLC-like (P variant) | 0 | DIRECT |
| Tubulin, C-terminal domain | 0 | DIRECT |
| Class I glutamine amidotransferases (GAT) | 0 | DIRECT |
| Ras-binding domain, RBD | 0 | DIRECT |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | DIRECT |
| 28-residue LRR | 0 | DIRECT |
| Internalin LRR domain | 0 | DIRECT |
| Anticodon-binding domain of Class II aaRS | 0 | DIRECT |
| Fatty acid binding protein-like | 0 | DIRECT |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | DIRECT |
| beta-sandwich domain of Sec23/24 | 0 | DIRECT |
| Glutaminase | 0 | DIRECT |
| Regulator of G-protein signaling, RGS | 0 | DIRECT |
| Inositol monophosphatase/fructose-1,6-bisphosphatase-like | 0 | DIRECT |
| Troponin I | 0 | DIRECT |
| Brix domain | 0 | DIRECT |
| Cadherin | 0 | DIRECT |
| Poly(ADP-ribose) polymerase, C-terminal domain | 0 | DIRECT |
| p120GAP domain-like | 0 | DIRECT |
| HCDH C-domain-like | 0 | DIRECT |
| Clc chloride channel | 0 | DIRECT |
| Carboxypeptidase regulatory domain | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
| NTF2-like | 0 | DIRECT |
| Clathrin adaptor core protein | 0 | DIRECT |
| Oxysterol-binding protein | 0 | DIRECT |
| Mitochondrial carrier | 0 | DIRECT |
| Alcohol dehydrogenase-like, C-terminal domain | 0 | DIRECT |
| Hsp90 middle domain | 0 | DIRECT |
| ALDH-like | 0 | DIRECT |
| Phosphotyrosine-binding domain (PTB) | 0 | DIRECT |
| Class I aldolase | 0 | DIRECT |
| Hexokinase | 0 | DIRECT |
| Hydantoinase (dihydropyrimidinase), catalytic domain | 0 | DIRECT |
| Ribosomal protein S10 | 0 | DIRECT |
| SAND domain | 0 | DIRECT |
| DPP6 N-terminal domain-like | 0 | DIRECT |
| Tetraspanin | 0 | DIRECT |
| NOL1/NOP2/sun | 0 | DIRECT |
| Biotin dependent carboxylase carboxyltransferase domain | 0 | DIRECT |
| Sir2 family of transcriptional regulators | 0 | DIRECT |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | DIRECT |
| Armadillo repeat | 0 | DIRECT |
| 2Fe-2S ferredoxin domains from multidomain proteins | 0 | DIRECT |
| Matrix metalloproteases, catalytic domain | 0 | DIRECT |
| F1F0 ATP synthase subunit C | 0 | DIRECT |
| CO dehydrogenase molybdoprotein N-domain-like | 0 | DIRECT |
| Molybdenum cofactor-binding domain | 0 | DIRECT |
| Dual specificity phosphatase-like | 0 | DIRECT |
| Double-stranded RNA-binding domain (dsRBD) | 0 | DIRECT |
| DEATH domain, DD | 0 | DIRECT |
| Inositol polyphosphate 5-phosphatase (IPP5) | 0 | DIRECT |
| Tandem AAA-ATPase domain | 0.003253 | INHERITED FROM: RNAi response variant || sick || organism stress response variant || organism UV response variant |
| Homeodomain | 0.02865 | INHERITED FROM: level of transgene expression variant || organism metabolism processing variant || carbon dioxide avoidance variant || sexually dimorphic physiology variant || carbon dioxide response variant || ectopic expression transgene |
| WD40-repeat | 0.03547 | INHERITED FROM: protein aggregation induced behavior variant || ivermectin response variant || antimicrobial gene expression variant || osmotic avoidance variant || ivermectin resistant || dauer defective |
| G proteins | 0.0367 | INHERITED FROM: chemosensory response variant || fat content variant || chemotaxis variant || organism metabolism processing variant || bacterially unswollen || carbon dioxide avoidance variant || osmotic integrity variant || protein subcellular localization variant || drug induced gene expression variant || carbon dioxide response variant || organism environmental stimulus response variant || pathogen release variant || aldicarb response variant |
| Protein kinases, catalytic subunit | 0.05096 | INHERITED FROM: protein phosphorylation reduced || protein expression variant || transgene expression reduced || metal response variant || octanol chemotaxis defective || alkaline pH chemotaxis variant || pathogen induced gene expression variant || chemotaxis variant || mechanosensation variant || conflicting sensory integration variant || colchicine resistant || anoxia resistant || second messenger mediated signaling variant || egg laying response to food variant || protein modification variant || protein phosphorylation variant || lipid synthesis increased || chemical response variant || kinase activity reduced || protein subcellular localization variant || positive chemotaxis variant || drug induced gene expression variant || oxygen response variant || phorbol ester resistant || metabolic pathway variant || aldicarb response variant || copper response variant |
| PDZ domain | 0.0628 | INHERITED FROM: protein expression variant || drug response variant || egg laying serotonin variant || aldicarb response variant |
| L-arabinose binding protein-like | 0.06908 | INHERITED FROM: chemosensory response variant || cation positive chemotaxis defective || alkaline pH chemotaxis variant || bromide chemotaxis defective || chemotaxis variant || bromide chemotaxis variant || iodide chemotaxis variant || anion positive chemotaxis defective || anion positive chemotaxis variant || cation positive chemotaxis variant || lithium chemotaxis defective || iodide chemotaxis defective || magnesium chemotaxis defective || organism environmental stimulus response variant |
| Canonical RBD | 0.07194 | INHERITED FROM: late larval arrest || antimicrobial gene expression variant || RNA expression variant || RNA processing variant || sick || starvation induced apoptosis variant || innate immune response variant || no induction of antimicrobial peptide expression after infection || mRNA export variant |
| MSP-like | 0.08714 | INHERITED FROM: slow growth || fat content variant || larval arrest || lipid metabolism variant || dauer lifespan extended || developmental growth variant || larval growth variant || dauer lifespan variant || dauer metabolism variant |
| Acetyl-CoA synthetase-like | 0.09131 | INHERITED FROM: lipid metabolism variant |
| ABC transporter ATPase domain-like | 0.09144 | INHERITED FROM: RNAi response variant || metal response variant || cadmium response variant || colchicine hypersensitive |
| CCCH zinc finger | 0.1004 | INHERITED FROM: RNA metabolism variant || mRNA expression ectopic || transgene expression variant || gene expression variant || ectopic expression transgene |
| Tetratricopeptide repeat (TPR) | 0.1364 | INHERITED FROM: organism metabolism processing variant |
| Cold shock DNA-binding domain-like | 0.1461 | INHERITED FROM: nonsense mRNA accumulation || mRNA surveillance defective || sick |
| Adenylyl and guanylyl cyclase catalytic domain | 0.1584 | INHERITED FROM: AWC odorant chemotaxis variant || chemosensory response variant || cation positive chemotaxis defective || diacetyl chemotaxis variant || alkaline pH chemotaxis variant || bromide chemotaxis defective || chemotaxis variant || bromide chemotaxis variant || osmotic avoidance variant || iodide chemotaxis variant || anion positive chemotaxis defective || second messenger mediated signaling variant || cation positive chemotaxis variant || lithium chemotaxis defective || AWC odorant chemotaxis defective || positive chemotaxis variant || carbon dioxide response variant || iodide chemotaxis defective || magnesium chemotaxis defective || organism environmental stimulus response variant |
| HLH, helix-loop-helix DNA-binding domain | 0.1584 | INHERITED FROM: pathogen resistance increased || gene expression level reduced || RNA expression variant || aqueous positive chemotaxis defective || lysine chemotaxis defective || ectopic expression transgene || hypoxia response variant || fungal resistance increased |
| Calcium ATPase, transduction domain A | 0.1932 | INHERITED FROM: nicotine hypersensitive || organism environmental stimulus response variant || drug hypersensitive |
| SH3-domain | 0.2223 | INHERITED FROM: protein expression variant || protein expression reduced || aldicarb response variant |
| Ankyrin repeat | 0.2237 | INHERITED FROM: octanol chemotaxis defective || organism heat response variant || octanol chemotaxis variant || odorant negative chemotaxis defective |
| HMG-box | 0.2317 | INHERITED FROM: maintenance of gene silencing variant || transgene expression variant |
| Elongation factors | 0.2317 | INHERITED FROM: protein protein interaction variant || proteasome core activity variant || protein modification variant || mRNA levels reduced || protein phosphorylation increased || protein aggregation variant || mRNA levels increased |
| DBL homology domain (DH-domain) | 0.2317 | INHERITED FROM: pathogen resistance increased || bacterially unswollen || organism pathogen response variant || organism environmental stimulus response variant || aldicarb response variant |
| Class I aminoacyl-tRNA synthetases (RS), catalytic domain | 0.2317 | INHERITED FROM: paraquat response variant || antimicrobial gene expression variant || organism metabolism processing variant || hypoxia resistant || transgene expression increased || gene expression variant || oxygen response variant || innate immune response variant || hypoxia response variant || paraquat resistant || organism environmental stimulus response variant |
| Histone lysine methyltransferases | 0.2317 | INHERITED FROM: RNAi response variant || life span variant || protein expression variant || mRNA expression variant || protein methylation variant || somatic transgene silencing variant || maintenance of gene silencing variant || histone methylation variant || protein metabolism variant || protein modification variant || ectopic expression antibody || shortened life span || metabolic pathway variant |
| Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain | 0.2317 | INHERITED FROM: organism metabolism processing variant || hypoxia resistant || transgene expression increased || transgene expression variant || gene expression variant || oxygen response variant || hypoxia response variant || organism environmental stimulus response variant |
| Cytochrome P450 | 0.235 | INHERITED FROM: metal response variant || metabolite content decreased || cadmium response variant |
| Pepsin-like | 0.254 | INHERITED FROM: protein protein interaction variant || pattern of transgene expression variant || organism metabolism processing variant || osmotic integrity variant || transgene subcellular localization variant || transgene expression variant || gene expression variant || protein aggregation variant || hypoosmotic shock hypersensitive || protein interaction variant |
| Metal cation-transporting ATPase, ATP-binding domain N | 0.2778 | INHERITED FROM: nicotine hypersensitive || organism environmental stimulus response variant || drug hypersensitive |
| Extended AAA-ATPase domain | 0.2974 | INHERITED FROM: life span variant || protein expression increased || spontaneous mutation rate increased || sick |
| Multidrug efflux transporter AcrB transmembrane domain | 0.2995 | INHERITED FROM: positive chemotaxis defective || embryo osmotic integrity defective early emb || egg integrity defective early emb || odorant chemosensory response variant || odorant positive chemotaxis defective |
| Bromodomain | 0.3042 | INHERITED FROM: acute functional tolerance to alcohol defective || anesthetic response variant || ethanol resistant || organism UV hypersensitive || sick || drug adaptation variant || anesthetic resistant || organism stress response variant || organism UV response variant |
| FYVE, a phosphatidylinositol-3-phosphate binding domain | 0.3042 | INHERITED FROM: aldicarb resistant || acetylcholinesterase inhibitor resistant |
| 6-phosphogluconate dehydrogenase-like, N-terminal domain | 0.3042 | INHERITED FROM: fat content variant || lipid metabolism variant |
| FAD/NAD-linked reductases, N-terminal and central domains | 0.3328 | INHERITED FROM: paraquat response variant || organism oxidative stress response variant || pesticide response variant |
| Meta-cation ATPase, catalytic domain P | 0.3648 | INHERITED FROM: nicotine hypersensitive || organism environmental stimulus response variant |
| Sm motif of small nuclear ribonucleoproteins, SNRNP | 0.3648 | INHERITED FROM: life span variant || protein protein interaction variant || pattern of transgene expression variant || sick || protein subcellular localization variant || protein aggregation variant || pattern protein expression variant |
| Crotonase-like | 0.3648 | INHERITED FROM: fat content variant || lipid metabolism variant |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.3912 | INHERITED FROM: nicotine resistant || drug response variant || mechanosensation variant || slowing response on food variant || DMPP response variant || sodium chloride chemotaxis variant || chemical response variant || aqueous chemosensory response variant || antihelmintic response variant || hypoosmotic shock hypersensitive || organism environmental stimulus response variant || cholinergic agonist resistant || selenium response variant |
| PX domain | 0.3959 | INHERITED FROM: protein expression variant || protein subcellular localization variant |
| TBP-associated factors, TAFs | 0.3959 | INHERITED FROM: transgene expression variant |
| FKBP immunophilin/proline isomerase | 0.4302 | INHERITED FROM: protein protein interaction variant || pattern of transgene expression variant || transgene subcellular localization variant || protein aggregation variant || protein interaction variant |
| GABA-aminotransferase-like | 0.4333 | INHERITED FROM: fat content reduced |
| ABC transporter transmembrane region | 0.4531 | INHERITED FROM: RNAi response variant || metal response variant || cadmium response variant || colchicine hypersensitive || organism environmental stimulus response variant |
| Glutathione S-transferase (GST), N-terminal domain | 0.4576 | INHERITED FROM: paraquat response variant || enzyme activity variant || organism heat hypersensitive || cadmium hypersensitive || enzyme activity reduced || organism electrophilic stress hypersensitive || organism environmental stimulus response variant || organism stress response variant |
| Protein kinase cysteine-rich domain (cys2, phorbol-binding domain) | 0.4651 | INHERITED FROM: antimicrobial gene expression variant || odorant positive chemotaxis variant || odorant chemosensory response variant || drug resistant || protein subcellular localization variant || drug induced gene expression variant || nose touch variant || organism pathogen response variant || aldicarb response variant |
| Nicotinic receptor ligand binding domain-like | 0.4695 | INHERITED FROM: nicotine resistant || drug response variant || mechanosensation variant || slowing response on food variant || DMPP response variant || sodium chloride chemotaxis variant || chemical response variant || aqueous chemosensory response variant || antihelmintic response variant || hypoosmotic shock hypersensitive || organism environmental stimulus response variant || cholinergic agonist resistant || selenium response variant |
| Acetylcholinesterase-like | 0.4759 | INHERITED FROM: enzyme activity variant || acetylcholinesterase activity variant || acetylcholinesterase reduced || enzyme activity reduced |
| Pyridoxal-dependent decarboxylase | 0.5141 | INHERITED FROM: carbon dioxide avoidance variant || carbon dioxide response variant || egg laying response to drug variant |
| Hect, E3 ligase catalytic domain | 0.5141 | INHERITED FROM: protein aggregation induced behavior variant || protein protein interaction variant || pattern of transgene expression variant || organism metabolism processing variant || transgene subcellular localization variant || transgene expression variant || gene expression variant || protein aggregation variant || protein interaction variant |
| I set domains | 0.5512 | INHERITED FROM: aldicarb resistant || growth rate variant || organism environmental stimulus response variant || protein degradation variant || aldicarb response variant |
| Calpain large subunit, middle domain (domain III) | 0.5574 | INHERITED FROM: protein metabolism variant || metabolic pathway variant || protein degradation variant |
| Gastric lipase | 0.5574 | INHERITED FROM: fat content variant || lipid metabolism variant |
| Myb/SANT domain | 0.5574 | INHERITED FROM: growth rate variant |
| Papain-like | 0.5702 | INHERITED FROM: protein protein interaction variant || pattern of transgene expression variant || organism metabolism processing variant || osmotic integrity variant || transgene expression variant || gene expression variant || protein aggregation variant || hypoosmotic shock hypersensitive || protein interaction variant |
| SH2 domain | 0.5774 | INHERITED FROM: protein expression variant || protein expression reduced || level of protein expression variant |
| WW domain | 0.5828 | INHERITED FROM: maintenance of gene silencing variant |
| Class I alpha-1;2-mannosidase, catalytic domain | 0.6079 | INHERITED FROM: protein protein interaction variant || extended life span || protein aggregation variant |
| UBC-related | 0.6224 | INHERITED FROM: late larval arrest || protein protein interaction variant || pattern of transgene expression variant || organism metabolism processing variant || transgene subcellular localization variant || transgene expression variant || gene expression variant || protein aggregation variant || protein interaction variant |
| Synaptotagmin-like (S variant) | 0.6492 | INHERITED FROM: drug response variant || drug resistant || protein subcellular localization variant || acetylcholinesterase inhibitor response variant || acetylcholinesterase inhibitor resistant || pattern protein expression variant |
| BTB/POZ domain | 0.686 | INHERITED FROM: protein aggregation induced behavior variant || chemical hypersensitive || L1 arrest || early larval arrest || resistant to protein aggregation induced paralysis |
| Ubiquitin carboxyl-terminal hydrolase, UCH | 0.7017 | INHERITED FROM: protein protein interaction variant || pattern of transgene expression variant || organism metabolism processing variant || maintenance of gene silencing variant || transgene expression variant || gene expression variant || protein aggregation variant || protein interaction variant |
| EF-hand modules in multidomain proteins | 0.7205 | INHERITED FROM: protein expression variant |
| Frizzled cysteine-rich domain | 0.7205 | INHERITED FROM: transgene expression reduced || antibody staining variant |
| Transforming growth factor (TGF)-beta | 0.7205 | INHERITED FROM: transgene expression reduced || level of transgene expression variant || drug response variant || nicotine response variant || levamisole response variant |
| PHD domain | 0.7245 | INHERITED FROM: RNAi response variant || protein methylation variant || RNAi resistant || protein modification variant || organism UV hypersensitive || ectopic expression transgene || organism environmental stimulus response variant || organism UV response variant |
| Voltage-gated potassium channels | 0.7473 | INHERITED FROM: adrenergic receptor antagonist response variant || serotonin resistant || AWA odorant chemotaxis variant || serotonin response variant || growth rate variant || protein degradation variant |
| H-NOX domain | 0.7822 | INHERITED FROM: carbon dioxide avoidance variant || carbon dioxide response variant |
| Cdc48 N-terminal domain-like | 0.7822 | INHERITED FROM: transgene expression reduced || protein protein interaction variant || protein metabolism variant || metabolic pathway variant || protein aggregation variant || protein interaction variant |
| MIT domain | 0.7822 | INHERITED FROM: protein protein interaction variant || protein aggregation variant || protein interaction variant |
| Bacterial lipase | 0.7822 | INHERITED FROM: fat content variant || lipid metabolism variant |
| Ubiquitin-related | 0.7828 | INHERITED FROM: protein protein interaction variant || organism metabolism processing variant || hypersensitive to protein aggregation induced paralysis || transgene expression variant || protein aggregation variant || protein interaction variant |
| LIM domain | 0.8583 | INHERITED FROM: protein expression reduced || level of protein expression variant || protein degradation variant |
| Glutathione S-transferase (GST), C-terminal domain | 0.8606 | INHERITED FROM: enzyme activity variant || organism heat hypersensitive || cadmium hypersensitive || enzyme activity reduced || organism electrophilic stress hypersensitive || organism environmental stimulus response variant || organism stress response variant |
| Leucine zipper domain | 0.88 | INHERITED FROM: pathogen susceptibility increased || transgene expression reduced || level of transgene expression variant || mRNA levels reduced || pore forming toxin response variant |
| Extended PAW domain | 0.895 | INHERITED FROM: protein protein interaction variant || pattern of transgene expression variant || transgene subcellular localization variant || protein aggregation variant || protein interaction variant |
| DnaQ-like 3'-5' exonuclease | 0.9066 | INHERITED FROM: RNAi response variant |
| Calmodulin-like | 0.9452 | INHERITED FROM: protein protein interaction variant || protein aggregation variant || protein interaction variant |
| NagD-like | 0.9576 | INHERITED FROM: dauer constitutive || dauer formation variant |
| Ribonuclease PH domain 1-like | 0.9576 | INHERITED FROM: early larval arrest |
| Ribonuclease PH domain 2-like | 0.9576 | INHERITED FROM: early larval arrest |
| Nuclear receptor ligand-binding domain | 0.9989 | INHERITED FROM: transgene expression reduced || gene expression level reduced || gene expression level high || SDS sensitive dauer || dauer resistance to harsh conditions variant || fat content increased |
| B-box zinc-binding domain | 1 | INHERITED FROM: protein protein interaction variant || transgene subcellular localization variant || transgene expression variant || gene expression variant || protein aggregation variant || protein interaction variant |
| Cyclophilin (peptidylprolyl isomerase) | 1 | INHERITED FROM: protein protein interaction variant || pattern of transgene expression variant || transgene subcellular localization variant || transgene expression variant || protein aggregation variant || protein interaction variant |
| PAZ domain | 1 | INHERITED FROM: RNAi response variant || RNA expression variant || maintenance of gene silencing variant || 21U RNA expression variant || RNAi enhanced || siRNA expression variant || mRNA levels increased |
| Nuclear receptor | 1 | INHERITED FROM: transgene expression reduced || gene expression level reduced || gene expression level high || SDS sensitive dauer || dauer resistance to harsh conditions variant || fat content increased |
| Glutathione peroxidase-like | 1 | INHERITED FROM: paraquat response variant || pesticide response variant |
| F-box domain | 1 | INHERITED FROM: protein aggregation induced behavior variant || resistant to protein aggregation induced paralysis |
| RING finger domain, C3HC4 | 1 | INHERITED FROM: protein protein interaction variant || pattern of transgene expression variant || organism metabolism processing variant || transgene subcellular localization variant || protein aggregation variant || protein interaction variant |
| Rhodopsin-like | 1 | INHERITED FROM: biogenic amine receptor antagonist resistant || serotonin resistant || serotonin hypersensitive || aqueous adaptation defective || drug withdrawal response variant || serotonin response variant || male tail curling serotonin variant || locomotion rate serotonin variant || serotonin induced fat reduction variant || organism pathogen response variant || egg laying response to drug variant || serotonin induced pumping variant |
| Choline/Carnitine O-acyltransferase | 1 | INHERITED FROM: fat content variant || lipid metabolism variant |
| N-acetyl transferase, NAT | 1 | INHERITED FROM: ectopic expression transgene |
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| Carbonic anhydrase | 0 | Direct |
| Myeloperoxidase-like | 0 | Direct |
| Polo-box duplicated region | 0 | Direct |
| Peptidylglycine alpha-hydroxylating monooxygenase, PHM | 0 | Direct |
| alpha-mannosidase, domain 2 | 0 | Direct |
| alpha-mannosidase, C-terminal domain | 0 | Direct |
| Second domain of FERM | 0 | Direct |
| Actin/HSP70 | 0 | Direct |
| Calcium ATPase, transmembrane domain M | 0 | Direct |
| Helical domain of Sec23/24 | 0 | Direct |
| YbiA-like | 0 | Direct |
| MOSC N-terminal domain-like | 0 | Direct |
| L30e/L7ae ribosomal proteins | 0 | Direct |
| MIR domain | 0 | Direct |
| XPF/Rad1/Mus81 nuclease | 0 | Direct |
| Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain | 0 | Direct |
| Third domain of FERM | 0 | Direct |
| Adenosine/AMP deaminase | 0 | Direct |
| LEM domain | 0 | Direct |
| Bactericidal permeability-increasing protein, BPI | 0 | Direct |
| Sec63 N-terminal domain | 0 | Direct |
| t-snare proteins | 0 | Direct |
| Pancreatic carboxypeptidases | 0 | Direct |
| HSP40/DnaJ peptide-binding domain | 0 | Direct |
| Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | Direct |
| D-aminoacid oxidase-like | 0 | Direct |
| Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | Direct |
| CoA transferase alpha subunit-like | 0 | Direct |
| Cell cycle control phosphatase, catalytic domain | 0 | Direct |
| SCF ubiquitin ligase complex WHB domain | 0 | Direct |
| PUA domain | 0 | Direct |
| Ubiquitin carboxyl-terminal hydrolase UCH-L | 0 | Direct |
| PhzC/PhzF-like | 0 | Direct |
| BEACH domain | 0 | Direct |
| Transducin (alpha subunit), insertion domain | 0 | Direct |
| Cullin homology domain | 0 | Direct |
| Adenain-like | 0 | Direct |
| Zn-finger domain of Sec23/24 | 0 | Direct |
| Arginine methyltransferase | 0 | Direct |
| YWTD domain | 0 | Direct |
| CO dehydrogenase flavoprotein N-terminal domain-like | 0 | Direct |
| YihX-like | 0 | Direct |
| Proprotein convertase P-domain | 0 | Direct |
| PDI-like | 0 | Direct |
| alpha-Amylases, C-terminal beta-sheet domain | 0 | Direct |
| Poly(A) polymerase, PAP, middle domain | 0 | Direct |
| Phosphatidylethanolamine binding protein | 0 | Direct |
| Medium chain acyl-CoA dehydrogenase-like, C-terminal domain | 0 | Direct |
| Pleckstrin-homology domain (PH domain) | 0 | Direct |
| MFPT repeat | 0 | Direct |
| FF domain | 0 | Direct |
| Linker histone H1/H5 | 0 | Direct |
| Skp1 dimerisation domain-like | 0 | Direct |
| Phosphoglucomutase, first 3 domains | 0 | Direct |
| Quinoprotein alcohol dehydrogenase-like | 0 | Direct |
| Complement control module/SCR domain | 0 | Direct |
| Hypothetical protein c14orf129, hspc210 | 0 | Direct |
| Smc hinge domain | 0 | Direct |
| Choline kinase | 0 | Direct |
| Glycolipid transfer protein, GLTP | 0 | Direct |
| Acireductone dioxygenase | 0 | Direct |
| Formate/glycerate dehydrogenases, NAD-domain | 0 | Direct |
| GAS2 domain | 0 | Direct |
| Biotinyl/lipoyl-carrier proteins and domains | 0 | Direct |
| Trunk domain of Sec23/24 | 0 | Direct |
| Thiolase-related | 0 | Direct |
| Protein prenyltransferases | 0 | Direct |
| Lactate & malate dehydrogenases, C-terminal domain | 0 | Direct |
| PABC (PABP) domain | 0 | Direct |
| HEAT repeat | 0 | Direct |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
| Clathrin coat assembly domain | 0 | Direct |
| HSP20 | 0 | Direct |
| Group II chaperonin (CCT, TRIC), intermediate domain | 0 | Direct |
| Succinyl-CoA synthetase domains | 0 | Direct |
| L-aminoacid/polyamine oxidase | 0 | Direct |
| Acylamino-acid-releasing enzyme, C-terminal donain | 0 | Direct |
| Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain | 0 | Direct |
| Rap/Ran-GAP | 0 | Direct |
| FHA domain | 0 | Direct |
| Glycerophosphoryl diester phosphodiesterase | 0 | Direct |
| Purine and uridine phosphorylases | 0 | Direct |
| First domain of FERM | 0 | Direct |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| AN1-like Zinc finger | 0 | Direct |
| Pepsin inhibitor-3 | 0 | Direct |
| DNA replication initiator (cdc21/cdc54) N-terminal domain | 0 | Direct |
| Transducin (heterotrimeric G protein), gamma chain | 0 | Direct |
| Poly(A) polymerase, PAP, C-terminal domain | 0 | Direct |
| DNA gyrase/MutL, N-terminal domain | 0 | Direct |
| UDP-glucose pyrophosphorylase | 0 | Direct |
| Cyclin | 0 | Direct |
| ValRS/IleRS/LeuRS editing domain | 0 | Direct |
| CUT domain | 0 | Direct |
| ets domain | 0 | Direct |
| PEP carboxykinase N-terminal domain | 0 | Direct |
| Retrovirus zinc finger-like domains | 0 | Direct |
| Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta | 0 | Direct |
| Methionine aminopeptidase, insert domain | 0 | Direct |
| Fibrinogen C-terminal domain-like | 0 | Direct |
| Annexin | 0 | Direct |
| Hedgehog C-terminal (Hog) autoprocessing domain | 0 | Direct |
| RhoGDI-like | 0 | Direct |
| VHS domain | 0 | Direct |
| 1,3-glucuronyltransferase | 0 | Direct |
| Histone deacetylase, HDAC | 0 | Direct |
| Alcohol dehydrogenase-like, N-terminal domain | 0 | Direct |
| Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | Direct |
| Type II chitinase | 0 | Direct |
| BC ATP-binding domain-like | 0 | Direct |
| Cofilin-like | 0 | Direct |
| acyl-CoA oxidase N-terminal domains | 0 | Direct |
| SAM (sterile alpha motif) domain | 0 | Direct |
| FtsH protease domain-like | 0 | Direct |
| Elafin-like | 0 | Direct |
| Proton glutamate symport protein | 0 | Direct |
| Ribosomal protein L1 | 0 | Direct |
| RNA-polymerase beta | 0 | Direct |
| Class II glutamine amidotransferases | 0 | Direct |
| CoA-binding domain | 0 | Direct |
| Pyk2-associated protein beta ARF-GAP domain | 0 | Direct |
| BC C-terminal domain-like | 0 | Direct |
| Cytoplasmic domain of inward rectifier potassium channel | 0 | Direct |
| Amylase, catalytic domain | 0 | Direct |
| Mammalian PLC | 0 | Direct |
| ARID domain | 0 | Direct |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
| GAPDH-like | 0 | Direct |
| SMAD domain | 0 | Direct |
| PurM C-terminal domain-like | 0 | Direct |
| Aminoacid dehydrogenase-like, C-terminal domain | 0 | Direct |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
| NHL repeat | 0 | Direct |
| Tubulin, GTPase domain | 0 | Direct |
| Myotubularin-like phosphatases | 0 | Direct |
| Aquaporin-like | 0 | Direct |
| Cullin repeat | 0 | Direct |
| Proteasome subunits | 0 | Direct |
| Profilin (actin-binding protein) | 0 | Direct |
| Reductases | 0 | Direct |
| PDEase | 0 | Direct |
| Intermediate filament protein, coiled coil region | 0 | Direct |
| Surp module (SWAP domain) | 0 | Direct |
| Spectrin repeat | 0 | Direct |
| Calpain large subunit, catalytic domain (domain II) | 0 | Direct |
| Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain | 0 | Direct |
| Chaperone J-domain | 0 | Direct |
| Phoshoinositide 3-kinase (PI3K) helical domain | 0 | Direct |
| CAT-like | 0 | Direct |
| FAD-dependent thiol oxidase | 0 | Direct |
| Anticodon-binding domain | 0 | Direct |
| Acyl-CoA thioesterase | 0 | Direct |
| Chromo domain | 0 | Direct |
| CRAL/TRIO N-terminal domain | 0 | Direct |
| SMAD MH1 domain | 0 | Direct |
| 14-3-3 protein | 0 | Direct |
| Heat shock protein 90, HSP90, N-terminal domain | 0 | Direct |
| Epoxide hydrolase | 0 | Direct |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | Direct |
| Lipovitellin-phosvitin complex, superhelical domain | 0 | Direct |
| Ribosomal protein L18 and S11 | 0 | Direct |
| Ngr ectodomain-like | 0 | Direct |
| Insulin-like | 0 | Direct |
| cAMP-binding domain | 0 | Direct |
| D-aminoacid oxidase, N-terminal domain | 0 | Direct |
| COMT-like | 0 | Direct |
| Regulator of chromosome condensation RCC1 | 0 | Direct |
| Serum paraoxonase/arylesterase 1, PON1 | 0 | Direct |
| Acyl-carrier protein (ACP) | 0 | Direct |
| Glycerol kinase | 0 | Direct |
| Tim10/DDP | 0 | Direct |
| Cdc48 domain 2-like | 0 | Direct |
| Erythroid transcription factor GATA-1 | 0 | Direct |
| WWE domain | 0 | Direct |
| alpha-mannosidase | 0 | Direct |
| Phoshoinositide 3-kinase (PI3K), catalytic domain | 0 | Direct |
| Lamin A/C globular tail domain | 0 | Direct |
| Dimeric isocitrate & isopropylmalate dehydrogenases | 0 | Direct |
| CO dehydrogenase ISP C-domain like | 0 | Direct |
| Sec1/munc18-like (SM) proteins | 0 | Direct |
| RecA protein-like (ATPase-domain) | 0 | Direct |
| Phosphate binding protein-like | 0 | Direct |
| Arfaptin, Rac-binding fragment | 0 | Direct |
| Hydantoinase (dihydropyrimidinase) | 0 | Direct |
| POU-specific domain | 0 | Direct |
| Glycogenin | 0 | Direct |
| Paired domain | 0 | Direct |
| Branched-chain alpha-keto acid dehydrogenase PP module | 0 | Direct |
| S-adenosylmethionine synthetase | 0 | Direct |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| ATP-dependent protease Lon (La), catalytic domain | 0 | Direct |
| SWIRM domain | 0 | Direct |
| Ferredoxin reductase FAD-binding domain-like | 0 | Direct |
| Citrate synthase | 0 | Direct |
| SWIB/MDM2 domain | 0 | Direct |
| PurM N-terminal domain-like | 0 | Direct |
| Cu,Zn superoxide dismutase-like | 0 | Direct |
| DNA repair protein MutS, domain III | 0 | Direct |
| beta 1,4 galactosyltransferase (b4GalT1) | 0 | Direct |
| Ran binding protein zinc finger-like | 0 | Direct |
| Inositol polyphosphate kinase (IPK) | 0 | Direct |
| Laminin G-like module | 0 | Direct |
| GYF domain | 0 | Direct |
| MutT-like | 0 | Direct |
| Sec63 C-terminal domain-like | 0 | Direct |
| Heme-dependent catalases | 0 | Direct |
| Pancreatic carboxypeptidase, activation domain | 0 | Direct |
| PaaI/YdiI-like | 0 | Direct |
| DPP6 catalytic domain-like | 0 | Direct |
| UBA domain | 0 | Direct |
| WGR domain | 0 | Direct |
| HD domain | 0 | Direct |
| YicI catalytic domain-like | 0 | Direct |
| Pumilio repeat | 0 | Direct |
| Translation initiation factor eIF4e | 0 | Direct |
| Group II chaperonin (CCT, TRIC), apical domain | 0 | Direct |
| Nucleoside diphosphate kinase, NDK | 0 | Direct |
| DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
| Bacterial exopeptidase dimerisation domain | 0 | Direct |
| Hormone receptor domain | 0 | Direct |
| Glycosyl transferases group 1 | 0 | Direct |
| Arylsulfatase | 0 | Direct |
| Single strand DNA-binding domain, SSB | 0 | Direct |
| Lesion bypass DNA polymerase (Y-family), catalytic domain | 0 | Direct |
| DNA gyrase/MutL, second domain | 0 | Direct |
| IF2B-like | 0 | Direct |
| Subtilases | 0 | Direct |
| Translational machinery components | 0 | Direct |
| 5' to 3' exonuclease catalytic domain | 0 | Direct |
| Group II chaperonin (CCT, TRIC), ATPase domain | 0 | Direct |
| RNA editing terminal uridyl transferase 2, RET2, domain 2 | 0 | Direct |
| Reprolysin-like | 0 | Direct |
| Blood coagulation inhibitor (disintegrin) | 0 | Direct |
| Poly(A) polymerase, PAP, N-terminal domain | 0 | Direct |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
| LysM domain | 0 | Direct |
| Integrin domains | 0 | Direct |
| Nop domain | 0 | Direct |
| DEP domain | 0 | Direct |
| BAR domain | 0 | Direct |
| Ubiquitin activating enzymes (UBA) | 0 | Direct |
| HAT/Suf repeat | 0 | Direct |
| BC N-terminal domain-like | 0 | Direct |
| U-box | 0 | Direct |
| Doublecortin (DC) | 0 | Direct |
| Ribokinase-like | 0 | Direct |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
| Filamin repeat (rod domain) | 0 | Direct |
| a tRNA synthase domain | 0 | Direct |
| Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains | 0 | Direct |
| Small-conductance potassium channel | 0 | Direct |
| HSP90 C-terminal domain | 0 | Direct |
| Band 7/SPFH domain | 0 | Direct |
| beta-Lactamase/D-ala carboxypeptidase | 0 | Direct |
| AMPK-beta glycogen binding domain-like | 0 | Direct |
| Sec7 domain | 0 | Direct |
| Phosphoribosyltransferases (PRTases) | 0 | Direct |
| LDH N-terminal domain-like | 0 | Direct |
| PEP carboxykinase C-terminal domain | 0 | Direct |
| Thyroglobulin type-1 domain | 0 | Direct |
| acyl-CoA oxidase C-terminal domains | 0 | Direct |
| Gamma-glutamyltranspeptidase-like | 0 | Direct |
| La domain | 0 | Direct |
| Nucleosome core histones | 0 | Direct |
| Sterol carrier protein, SCP | 0 | Direct |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | Direct |
| Branched-chain alpha-keto acid dehydrogenase Pyr module | 0 | Direct |
| LacY-like proton/sugar symporter | 0 | Direct |
| MIF4G domain-like | 0 | Direct |
| Cation efflux protein transmembrane domain-like | 0 | Direct |
| Domain of poly(ADP-ribose) polymerase | 0 | Direct |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
| Chitinase insertion domain | 0 | Direct |
| RNA-polymerase beta-prime | 0 | Direct |
| Cation efflux protein cytoplasmic domain-like | 0 | Direct |
| alpha-catenin/vinculin | 0 | Direct |
| PLC-like (P variant) | 0 | Direct |
| Tubulin, C-terminal domain | 0 | Direct |
| Class I glutamine amidotransferases (GAT) | 0 | Direct |
| Ras-binding domain, RBD | 0 | Direct |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | Direct |
| 28-residue LRR | 0 | Direct |
| Internalin LRR domain | 0 | Direct |
| Anticodon-binding domain of Class II aaRS | 0 | Direct |
| Fatty acid binding protein-like | 0 | Direct |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | Direct |
| beta-sandwich domain of Sec23/24 | 0 | Direct |
| Glutaminase | 0 | Direct |
| Regulator of G-protein signaling, RGS | 0 | Direct |
| Inositol monophosphatase/fructose-1,6-bisphosphatase-like | 0 | Direct |
| Troponin I | 0 | Direct |
| Brix domain | 0 | Direct |
| Cadherin | 0 | Direct |
| Poly(ADP-ribose) polymerase, C-terminal domain | 0 | Direct |
| p120GAP domain-like | 0 | Direct |
| HCDH C-domain-like | 0 | Direct |
| Clc chloride channel | 0 | Direct |
| Carboxypeptidase regulatory domain | 0 | Direct |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
| NTF2-like | 0 | Direct |
| Clathrin adaptor core protein | 0 | Direct |
| Oxysterol-binding protein | 0 | Direct |
| Mitochondrial carrier | 0 | Direct |
| Alcohol dehydrogenase-like, C-terminal domain | 0 | Direct |
| Hsp90 middle domain | 0 | Direct |
| ALDH-like | 0 | Direct |
| Phosphotyrosine-binding domain (PTB) | 0 | Direct |
| Class I aldolase | 0 | Direct |
| Hexokinase | 0 | Direct |
| Hydantoinase (dihydropyrimidinase), catalytic domain | 0 | Direct |
| Ribosomal protein S10 | 0 | Direct |
| SAND domain | 0 | Direct |
| DPP6 N-terminal domain-like | 0 | Direct |
| Tetraspanin | 0 | Direct |
| NOL1/NOP2/sun | 0 | Direct |
| Biotin dependent carboxylase carboxyltransferase domain | 0 | Direct |
| Sir2 family of transcriptional regulators | 0 | Direct |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | Direct |
| Armadillo repeat | 0 | Direct |
| 2Fe-2S ferredoxin domains from multidomain proteins | 0 | Direct |
| Matrix metalloproteases, catalytic domain | 0 | Direct |
| F1F0 ATP synthase subunit C | 0 | Direct |
| CO dehydrogenase molybdoprotein N-domain-like | 0 | Direct |
| Molybdenum cofactor-binding domain | 0 | Direct |
| Dual specificity phosphatase-like | 0 | Direct |
| Double-stranded RNA-binding domain (dsRBD) | 0 | Direct |
| DEATH domain, DD | 0 | Direct |
| Inositol polyphosphate 5-phosphatase (IPP5) | 0 | Direct |
| Tandem AAA-ATPase domain | 0.003253 | Inherited |
| Homeodomain | 0.02865 | Inherited |
| WD40-repeat | 0.03547 | Inherited |
| G proteins | 0.0367 | Inherited |
| Protein kinases, catalytic subunit | 0.05096 | Inherited |
| PDZ domain | 0.0628 | Inherited |
| L-arabinose binding protein-like | 0.06908 | Inherited |
| Canonical RBD | 0.07194 | Inherited |
| MSP-like | 0.08714 | Inherited |
| Acetyl-CoA synthetase-like | 0.09131 | Inherited |
| ABC transporter ATPase domain-like | 0.09144 | Inherited |
| CCCH zinc finger | 0.1004 | Inherited |
| Tetratricopeptide repeat (TPR) | 0.1364 | Inherited |
| Cold shock DNA-binding domain-like | 0.1461 | Inherited |
| Adenylyl and guanylyl cyclase catalytic domain | 0.1584 | Inherited |
| HLH, helix-loop-helix DNA-binding domain | 0.1584 | Inherited |
| Calcium ATPase, transduction domain A | 0.1932 | Inherited |
| SH3-domain | 0.2223 | Inherited |
| Ankyrin repeat | 0.2237 | Inherited |
| HMG-box | 0.2317 | Inherited |
| Elongation factors | 0.2317 | Inherited |
| DBL homology domain (DH-domain) | 0.2317 | Inherited |
| Class I aminoacyl-tRNA synthetases (RS), catalytic domain | 0.2317 | Inherited |
| Histone lysine methyltransferases | 0.2317 | Inherited |
| Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain | 0.2317 | Inherited |
| Cytochrome P450 | 0.235 | Inherited |
| Pepsin-like | 0.254 | Inherited |
| Metal cation-transporting ATPase, ATP-binding domain N | 0.2778 | Inherited |
| Extended AAA-ATPase domain | 0.2974 | Inherited |
| Multidrug efflux transporter AcrB transmembrane domain | 0.2995 | Inherited |
| Bromodomain | 0.3042 | Inherited |
| FYVE, a phosphatidylinositol-3-phosphate binding domain | 0.3042 | Inherited |
| 6-phosphogluconate dehydrogenase-like, N-terminal domain | 0.3042 | Inherited |
| FAD/NAD-linked reductases, N-terminal and central domains | 0.3328 | Inherited |
| Meta-cation ATPase, catalytic domain P | 0.3648 | Inherited |
| Sm motif of small nuclear ribonucleoproteins, SNRNP | 0.3648 | Inherited |
| Crotonase-like | 0.3648 | Inherited |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.3912 | Inherited |
| PX domain | 0.3959 | Inherited |
| TBP-associated factors, TAFs | 0.3959 | Inherited |
| FKBP immunophilin/proline isomerase | 0.4302 | Inherited |
| GABA-aminotransferase-like | 0.4333 | Inherited |
| ABC transporter transmembrane region | 0.4531 | Inherited |
| Glutathione S-transferase (GST), N-terminal domain | 0.4576 | Inherited |
| Protein kinase cysteine-rich domain (cys2, phorbol-binding domain) | 0.4651 | Inherited |
| Nicotinic receptor ligand binding domain-like | 0.4695 | Inherited |
| Acetylcholinesterase-like | 0.4759 | Inherited |
| Pyridoxal-dependent decarboxylase | 0.5141 | Inherited |
| Hect, E3 ligase catalytic domain | 0.5141 | Inherited |
| I set domains | 0.5512 | Inherited |
| Calpain large subunit, middle domain (domain III) | 0.5574 | Inherited |
| Gastric lipase | 0.5574 | Inherited |
| Myb/SANT domain | 0.5574 | Inherited |
| Papain-like | 0.5702 | Inherited |
| SH2 domain | 0.5774 | Inherited |
| WW domain | 0.5828 | Inherited |
| Class I alpha-1;2-mannosidase, catalytic domain | 0.6079 | Inherited |
| UBC-related | 0.6224 | Inherited |
| Synaptotagmin-like (S variant) | 0.6492 | Inherited |
| BTB/POZ domain | 0.686 | Inherited |
| Ubiquitin carboxyl-terminal hydrolase, UCH | 0.7017 | Inherited |
| EF-hand modules in multidomain proteins | 0.7205 | Inherited |
| Frizzled cysteine-rich domain | 0.7205 | Inherited |
| Transforming growth factor (TGF)-beta | 0.7205 | Inherited |
| PHD domain | 0.7245 | Inherited |
| Voltage-gated potassium channels | 0.7473 | Inherited |
| H-NOX domain | 0.7822 | Inherited |
| Cdc48 N-terminal domain-like | 0.7822 | Inherited |
| MIT domain | 0.7822 | Inherited |
| Bacterial lipase | 0.7822 | Inherited |
| Ubiquitin-related | 0.7828 | Inherited |
| LIM domain | 0.8583 | Inherited |
| Glutathione S-transferase (GST), C-terminal domain | 0.8606 | Inherited |
| Leucine zipper domain | 0.88 | Inherited |
| Extended PAW domain | 0.895 | Inherited |
| DnaQ-like 3'-5' exonuclease | 0.9066 | Inherited |
| Calmodulin-like | 0.9452 | Inherited |
| NagD-like | 0.9576 | Inherited |
| Ribonuclease PH domain 1-like | 0.9576 | Inherited |
| Ribonuclease PH domain 2-like | 0.9576 | Inherited |
| Nuclear receptor ligand-binding domain | 0.9989 | Inherited |
| B-box zinc-binding domain | 1 | Inherited |
| Cyclophilin (peptidylprolyl isomerase) | 1 | Inherited |
| PAZ domain | 1 | Inherited |
| Nuclear receptor | 1 | Inherited |
| Glutathione peroxidase-like | 1 | Inherited |
| F-box domain | 1 | Inherited |
| RING finger domain, C3HC4 | 1 | Inherited |
| Rhodopsin-like | 1 | Inherited |
| Choline/Carnitine O-acyltransferase | 1 | Inherited |
| N-acetyl transferase, NAT | 1 | Inherited |
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A presence/absence matrix is generated using protein domain
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Supra-domain (including individual superfamily)
(show details)
Supra-domains annotated to this WP term (Not in SPWP)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
| Second domain of FERM | 0 | DIRECT |
| Thyroglobulin type-1 domain | 0 | DIRECT |
| Smc hinge domain | 0 | DIRECT |
| S-adenosylmethionine synthetase | 0 | DIRECT |
| Troponin coil-coiled subunits | 0 | DIRECT |
| Tubby C-terminal domain-like | 0 | DIRECT |
| Transducin (alpha subunit), insertion domain | 0 | DIRECT |
| Zn-finger domain of Sec23/24 | 0 | DIRECT |
| Cdc48 domain 2-like | 0 | DIRECT |
| Invertebrate chitin-binding proteins | 0 | DIRECT |
| Elafin-like | 0 | DIRECT |
| Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | DIRECT |
| dsRNA-binding domain-like | 0 | DIRECT |
| BEACH domain | 0 | DIRECT |
| R3H domain | 0 | DIRECT |
| Kringle-like | 0 | DIRECT |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
| Actin-like ATPase domain | 0 | DIRECT |
| Ribosomal protein L10-like | 0 | DIRECT |
| Insulin-like | 0 | DIRECT |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | DIRECT |
| 2Fe-2S ferredoxin-like | 0 | DIRECT |
| Protease propeptides/inhibitors | 0 | DIRECT |
| PK beta-barrel domain-like | 0 | DIRECT |
| ArfGap/RecO-like zinc finger | 0 | DIRECT |
| DEATH domain | 0 | DIRECT |
| Restriction endonuclease-like | 0 | DIRECT |
| YWTD domain | 0 | DIRECT |
| YbiA-like | 0 | DIRECT |
| Carbohydrate phosphatase | 0 | DIRECT |
| Class II aaRS ABD-related | 0 | DIRECT |
| PABC (PABP) domain | 0 | DIRECT |
| Retrovirus zinc finger-like domains | 0 | DIRECT |
| Galactose oxidase, central domain | 0 | DIRECT |
| Rudiment single hybrid motif | 0 | DIRECT |
| Succinyl-CoA synthetase domains | 0 | DIRECT |
| Mitochondrial carrier | 0 | DIRECT |
| Fibrinogen C-terminal domain-like | 0 | DIRECT |
| PEP carboxykinase-like | 0 | DIRECT |
| Cadherin-like | 0 | DIRECT |
| cAMP-binding domain-like | 0 | DIRECT |
| HSP90 C-terminal domain | 0 | DIRECT |
| Cu,Zn superoxide dismutase-like | 0 | DIRECT |
| Arginase/deacetylase | 0 | DIRECT |
| Phoshotransferase/anion transport protein | 0 | DIRECT |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Profilin (actin-binding protein) | 0 | DIRECT |
| Translational machinery components | 0 | DIRECT |
| Complement control module/SCR domain | 0 | DIRECT |
| Ferritin-like | 0 | DIRECT |
| AN1-like Zinc finger | 0 | DIRECT |
| CAD & PB1 domains | 0 | DIRECT |
| Class I glutamine amidotransferase-like | 0 | DIRECT |
| SPOC domain-like | 0 | DIRECT |
| MgtE membrane domain-like | 0 | DIRECT |
| Citrate synthase | 0 | DIRECT |
| Isocitrate/Isopropylmalate dehydrogenase-like | 0 | DIRECT |
| ValRS/IleRS/LeuRS editing domain | 0 | DIRECT |
| Galactose mutarotase-like | 0 | DIRECT |
| Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
| lambda repressor-like DNA-binding domains | 0 | DIRECT |
| LDH C-terminal domain-like | 0 | DIRECT |
| RBP11-like subunits of RNA polymerase | 0 | DIRECT |
| Subdomain of clathrin and coatomer appendage domain | 0 | DIRECT |
| Band 7/SPFH domain | 0 | DIRECT |
| Ribulose-phoshate binding barrel | 0 | DIRECT |
| LysM domain | 0 | DIRECT |
| Acyl-CoA dehydrogenase NM domain-like | 0 | DIRECT |
| PreATP-grasp domain | 0 | DIRECT |
| Thiolase-like | 0 | DIRECT |
| FF domain | 0 | DIRECT |
| Terpenoid synthases | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
| Subtilisin-like | 0 | DIRECT |
| GroEL apical domain-like | 0 | DIRECT |
| ALDH-like | 0 | DIRECT |
| Tubulin nucleotide-binding domain-like | 0 | DIRECT |
| PAP/OAS1 substrate-binding domain | 0 | DIRECT |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | DIRECT |
| Phosphoglucomutase, first 3 domains | 0 | DIRECT |
| Hedgehog/intein (Hint) domain | 0 | DIRECT |
| F1F0 ATP synthase subunit C | 0 | DIRECT |
| PHM/PNGase F | 0 | DIRECT |
| Ribosomal L27 protein-like | 0 | DIRECT |
| ENTH/VHS domain | 0 | DIRECT |
| CBD9-like | 0 | DIRECT |
| Chitinase insertion domain | 0 | DIRECT |
| Creatinase/prolidase N-terminal domain | 0 | DIRECT |
| SAICAR synthase-like | 0 | DIRECT |
| FtsH protease domain-like | 0 | DIRECT |
| Doublecortin (DC) | 0 | DIRECT |
| Sec1/munc18-like (SM) proteins | 0 | DIRECT |
| Glutathione synthetase ATP-binding domain-like | 0 | DIRECT |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
| Formate/glycerate dehydrogenase catalytic domain-like | 0 | DIRECT |
| SCP-like | 0 | DIRECT |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | DIRECT |
| Pepsin inhibitor-3 | 0 | DIRECT |
| Glycolipid transfer protein, GLTP | 0 | DIRECT |
| GroEL equatorial domain-like | 0 | DIRECT |
| Blood coagulation inhibitor (disintegrin) | 0 | DIRECT |
| Tricorn protease domain 2 | 0 | DIRECT |
| 14-3-3 protein | 0 | DIRECT |
| Zn-binding ribosomal proteins | 0 | DIRECT |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | DIRECT |
| Pentein | 0 | DIRECT |
| Periplasmic binding protein-like II | 0 | DIRECT |
| Sec63 N-terminal domain-like | 0 | DIRECT |
| Bacterial exopeptidase dimerisation domain | 0 | DIRECT |
| Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0 | DIRECT |
| GYF domain | 0 | DIRECT |
| Polo-box domain | 0 | DIRECT |
| Purine and uridine phosphorylases | 0 | DIRECT |
| t-snare proteins | 0 | DIRECT |
| Chromo domain-like | 0 | DIRECT |
| Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
| Cation efflux protein cytoplasmic domain-like | 0 | DIRECT |
| Spectrin repeat | 0 | DIRECT |
| ARID-like | 0 | DIRECT |
| Single hybrid motif | 0 | DIRECT |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
| SWIB/MDM2 domain | 0 | DIRECT |
| 3-carboxy-cis,cis-mucoante lactonizing enzyme | 0 | DIRECT |
| Helical domain of Sec23/24 | 0 | DIRECT |
| Phosphoenolpyruvate/pyruvate domain | 0 | DIRECT |
| CO dehydrogenase molybdoprotein N-domain-like | 0 | DIRECT |
| Carboxypeptidase regulatory domain-like | 0 | DIRECT |
| PLC-like phosphodiesterases | 0 | DIRECT |
| Clathrin adaptor appendage domain | 0 | DIRECT |
| Outer arm dynein light chain 1 | 0 | DIRECT |
| Carbon-nitrogen hydrolase | 0 | DIRECT |
| alpha/beta knot | 0 | DIRECT |
| Hypothetical protein c14orf129, hspc210 | 0 | DIRECT |
| Proton glutamate symport protein | 0 | DIRECT |
| Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | DIRECT |
| PEBP-like | 0 | DIRECT |
| MIR domain | 0 | DIRECT |
| HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
| Carbonic anhydrase | 0 | DIRECT |
| Ribosomal protein S10 | 0 | DIRECT |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
| Nop domain | 0 | DIRECT |
| MOSC N-terminal domain-like | 0 | DIRECT |
| CRAL/TRIO N-terminal domain | 0 | DIRECT |
| Heme-dependent peroxidases | 0 | DIRECT |
| Lamin A/C globular tail domain | 0 | DIRECT |
| DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
| LEM domain | 0 | DIRECT |
| SIS domain | 0 | DIRECT |
| Integrin domains | 0 | DIRECT |
| Thiamin diphosphate-binding fold (THDP-binding) | 0 | DIRECT |
| Putative DNA-binding domain | 0 | DIRECT |
| TK C-terminal domain-like | 0 | DIRECT |
| Terpenoid cyclases/Protein prenyltransferases | 0 | DIRECT |
| Molybdenum cofactor-binding domain | 0 | DIRECT |
| WGR domain-like | 0 | DIRECT |
| Cytochrome c | 0 | DIRECT |
| VPS9 domain | 0 | DIRECT |
| Cullin homology domain | 0 | DIRECT |
| Cation efflux protein transmembrane domain-like | 0 | DIRECT |
| Domain of poly(ADP-ribose) polymerase | 0 | DIRECT |
| PLP-binding barrel | 0 | DIRECT |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| beta-lactamase/transpeptidase-like | 0 | DIRECT |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0 | DIRECT |
| Cullin repeat-like | 0 | DIRECT |
| Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | DIRECT |
| eIF4e-like | 0 | DIRECT |
| GAS2 domain-like | 0 | DIRECT |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | DIRECT |
| Tim10-like | 0 | DIRECT |
| ThrRS/AlaRS common domain | 0 | DIRECT |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | DIRECT |
| Activating enzymes of the ubiquitin-like proteins | 0 | DIRECT |
| PUA domain-like | 0 | DIRECT |
| Annexin | 0 | DIRECT |
| Small-conductance potassium channel | 0 | DIRECT |
| PurM N-terminal domain-like | 0 | DIRECT |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
| GroES-like | 0 | DIRECT |
| MFPT repeat-like | 0 | DIRECT |
| Acid phosphatase/Vanadium-dependent haloperoxidase | 0 | DIRECT |
| HSP20-like chaperones | 0 | DIRECT |
| Rap/Ran-GAP | 0 | DIRECT |
| HCP-like | 0 | DIRECT |
| L30e-like | 0 | DIRECT |
| DNA repair protein MutS, domain III | 0 | DIRECT |
| Chaperone J-domain | 0 | DIRECT |
| GAT-like domain | 0 | DIRECT |
| Radical SAM enzymes | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
| Nucleoside diphosphate kinase, NDK | 0 | DIRECT |
| Integrin alpha N-terminal domain | 0 | DIRECT |
| Aminoacid dehydrogenase-like, N-terminal domain | 0 | DIRECT |
| Lipovitellin-phosvitin complex, superhelical domain | 0 | DIRECT |
| Cystatin/monellin | 0 | DIRECT |
| SAND domain-like | 0 | DIRECT |
| Intermediate filament protein, coiled coil region | 0 | DIRECT |
| Diaminopimelate epimerase-like | 0 | DIRECT |
| PEP carboxykinase N-terminal domain | 0 | DIRECT |
| Tubulin C-terminal domain-like | 0 | DIRECT |
| Ribosomal protein L1 | 0 | DIRECT |
| L-aspartase-like | 0 | DIRECT |
| Aldolase | 0 | DIRECT |
| Aquaporin-like | 0 | DIRECT |
| Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | DIRECT |
| Skp1 dimerisation domain-like | 0 | DIRECT |
| alpha-catenin/vinculin-like | 0 | DIRECT |
| CO dehydrogenase ISP C-domain like | 0 | DIRECT |
| ADP-ribosylation | 0 | DIRECT |
| Nucleotidyltransferase | 0 | DIRECT |
| NagB/RpiA/CoA transferase-like | 0 | DIRECT |
| TGS-like | 0 | DIRECT |
| PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | DIRECT |
| Families 57/38 glycoside transferase middle domain | 0 | DIRECT |
| PYP-like sensor domain (PAS domain) | 0 | DIRECT |
| Surp module (SWAP domain) | 0 | DIRECT |
| Ran binding protein zinc finger-like | 0 | DIRECT |
| PIN domain-like | 0 | DIRECT |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
| Sec7 domain | 0 | DIRECT |
| GroEL-intermediate domain like | 0 | DIRECT |
| Hormone receptor domain | 0 | DIRECT |
| Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
| Nucleoporin domain | 0 | DIRECT |
| Clc chloride channel | 0 | DIRECT |
| Ribokinase-like | 0 | DIRECT |
| ISP domain | 0 | DIRECT |
| Ribosomal proteins S24e, L23 and L15e | 0 | DIRECT |
| FAD-dependent thiol oxidase | 0 | DIRECT |
| PurM C-terminal domain-like | 0 | DIRECT |
| Heme-dependent catalase-like | 0 | DIRECT |
| WWE domain | 0 | DIRECT |
| Transducin (heterotrimeric G protein), gamma chain | 0 | DIRECT |
| Oxysterol-binding protein-like | 0 | DIRECT |
| DNA ligase/mRNA capping enzyme, catalytic domain | 0 | DIRECT |
| JAB1/MPN domain | 0 | DIRECT |
| PGBD-like | 0 | DIRECT |
| SMAD MH1 domain | 0 | DIRECT |
| P-loop containing nucleoside triphosphate hydrolases | 0.0000008853 | DIRECT |
| PH domain-like | 0.00003915 | DIRECT |
| Histone-fold | 0.0001013 | DIRECT |
| Periplasmic binding protein-like I | 0.01652 | INHERITED FROM: iodide chemotaxis variant || AWC odorant chemotaxis variant || benzaldehyde chemotaxis variant || aqueous chemosensory response variant || diacetyl chemotaxis variant || chemotaxis variant || AWC odorant chemotaxis defective || lithium chemotaxis defective || alkaline pH chemotaxis variant || mechanosensation variant || bromide chemotaxis variant || organism environmental stimulus response variant || chemosensory response variant || iodide chemotaxis defective || aqueous positive chemotaxis variant || positive chemotaxis variant || magnesium chemotaxis defective || memory retention defective || carbon dioxide avoidance variant || chemical response variant || bromide chemotaxis defective || second messenger mediated signaling variant |
| TPR-like | 0.01748 | INHERITED FROM: associative learning variant || ivermectin resistant || ivermectin response variant || antihelmintic response variant || dauer defective || light body touch resistant || positive chemotaxis defective |
| Protein kinase-like (PK-like) | 0.025 | INHERITED FROM: pathogen induced gene expression variant || mid larval arrest || protein phosphorylation variant || conflicting sensory integration variant || lipid synthesis increased || metal response variant || kinase activity reduced || drug induced gene expression variant || chemotaxis variant || octanol chemotaxis defective || metabolic pathway variant || egg laying response to food variant || anoxia resistant || protein phosphorylation reduced || alkaline pH chemotaxis variant || mechanosensation variant || colchicine resistant || organism environmental stimulus response variant || positive chemotaxis variant || protein subcellular localization variant || life span variant || organism osmostic stress hypersensitive || aldicarb response variant || chemical response variant || protein expression variant || copper response variant || second messenger mediated signaling variant |
| ARM repeat | 0.03364 | INHERITED FROM: RNAi response variant || sick || organism metabolism processing variant || organism hypersensitive ionizing radiation || protein expression variant || gene expression variant |
| PapD-like | 0.03378 | INHERITED FROM: slow growth || larval arrest || lipid metabolism variant || fat content variant || developmental growth variant || larval growth variant |
| Homeodomain-like | 0.03578 | INHERITED FROM: inhibitor of serotonin uptake variant || adrenergic receptor antagonist response variant || imipramine resistant || ectopic expression transgene || carbon dioxide response variant || egg laying imipramine resistant || level of transgene expression variant || protein degradation variant || organism metabolism processing variant || sexually dimorphic physiology variant || carbon dioxide avoidance variant || growth rate variant |
| WD40 repeat-like | 0.0421 | INHERITED FROM: antimicrobial gene expression variant || protein aggregation variant || osmotic avoidance variant || protein protein interaction variant || organism metabolism processing variant || protein aggregation induced behavior variant || early larval arrest || late larval arrest |
| PDZ domain-like | 0.04527 | INHERITED FROM: acetylcholinesterase inhibitor response variant || aldicarb response variant || drug resistant || protein expression variant |
| Nucleic acid-binding proteins | 0.05767 | INHERITED FROM: hypoxia resistant || hydroxyurea hypersensitive || mRNA surveillance defective || sick || nonsense mRNA accumulation || hydroxyurea response variant |
| Calponin-homology domain, CH-domain | 0.06018 | INHERITED FROM: protein expression variant |
| Acetyl-CoA synthetase-like | 0.06698 | INHERITED FROM: lipid metabolism variant |
| Cyclin-like | 0.06698 | INHERITED FROM: protein phosphorylation variant || protein phosphorylation reduced |
| "Winged helix" DNA-binding domain | 0.06992 | INHERITED FROM: shortened life span || protein aggregation variant || chemical hypersensitive || anesthetic response variant || protein expression increased || protein protein interaction variant || life span variant || organism metabolism processing variant || germline transgene silencing variant || protein aggregation induced behavior variant || paraquat hypersensitive || spontaneous mutation rate increased || growth rate variant |
| CCCH zinc finger | 0.07443 | INHERITED FROM: RNA metabolism variant || transgene expression variant || ectopic expression transgene || mRNA expression ectopic || gene expression variant |
| Translation proteins | 0.09202 | INHERITED FROM: proteasome core activity variant || protein aggregation variant || mRNA levels increased || protein phosphorylation increased || transgene expression variant || sick || protein protein interaction variant || organism metabolism processing variant || gene expression variant |
| Nucleotide cyclase | 0.1127 | INHERITED FROM: iodide chemotaxis variant || AWC odorant chemotaxis variant || diacetyl chemotaxis variant || chemotaxis variant || AWC odorant chemotaxis defective || lithium chemotaxis defective || alkaline pH chemotaxis variant || bromide chemotaxis variant || osmotic avoidance variant || anion positive chemotaxis variant || organism environmental stimulus response variant || chemosensory response variant || anion positive chemotaxis defective || carbon dioxide response variant || iodide chemotaxis defective || positive chemotaxis variant || magnesium chemotaxis defective || cation positive chemotaxis variant || cation positive chemotaxis defective || bromide chemotaxis defective || second messenger mediated signaling variant |
| HLH, helix-loop-helix DNA-binding domain | 0.1127 | INHERITED FROM: hypoxia response variant || RNA expression variant || pathogen resistance increased || ectopic expression transgene || gene expression level reduced || lysine chemotaxis defective || fungal resistance increased || organism metabolism processing variant || aqueous positive chemotaxis defective |
| SMAD/FHA domain | 0.1136 | INHERITED FROM: fat content reduced || aldicarb response variant |
| Calcium ATPase, transmembrane domain M | 0.1261 | INHERITED FROM: organism environmental stimulus response variant || drug hypersensitive || nicotine hypersensitive || lipid composition variant |
| Ankyrin repeat | 0.1275 | INHERITED FROM: octanol chemotaxis variant || organism heat response variant || chemotaxis variant || octanol chemotaxis defective || odorant negative chemotaxis defective || mechanosensation variant || chemosensory response variant |
| Regulator of G-protein signaling, RGS | 0.1401 | INHERITED FROM: chemotaxis variant || mechanosensation variant || negative chemotaxis variant |
| Metal cation-transporting ATPase, ATP-binding domain N | 0.1401 | INHERITED FROM: organism environmental stimulus response variant || drug hypersensitive || nicotine hypersensitive || lipid composition variant |
| Cytochrome P450 | 0.1452 | INHERITED FROM: metabolite content decreased || metal response variant || cadmium response variant |
| SH3-domain | 0.1477 | INHERITED FROM: protein expression reduced || aldicarb response variant || protein expression variant |
| E set domains | 0.1522 | INHERITED FROM: paraquat hypersensitive |
| Calcium ATPase, transduction domain A | 0.1554 | INHERITED FROM: organism environmental stimulus response variant || drug hypersensitive || nicotine hypersensitive |
| Acid proteases | 0.1554 | INHERITED FROM: osmotic integrity variant || protein aggregation variant || transgene subcellular localization variant || hypoosmotic shock hypersensitive || transgene expression variant || protein protein interaction variant || organism metabolism processing variant || gene expression variant || protein interaction variant |
| EGF/Laminin | 0.1652 | INHERITED FROM: octanol chemotaxis variant || octanol chemotaxis defective || odorant negative chemotaxis defective || negative chemotaxis variant |
| Cysteine-rich domain | 0.1712 | INHERITED FROM: antimicrobial gene expression variant || odorant positive chemotaxis variant || organism pathogen response variant || drug induced gene expression variant || acetylcholinesterase inhibitor response variant || odorant chemosensory response variant || positive chemotaxis variant || protein subcellular localization variant || bacterially unswollen || organism metabolism processing variant || aldicarb response variant |
| Quinoprotein alcohol dehydrogenase-like | 0.1723 | INHERITED FROM: mid larval arrest || hypoxia response variant || mRNA levels increased || L2 arrest || protein degradation variant || drug response variant |
| Multidrug efflux transporter AcrB transmembrane domain | 0.1858 | INHERITED FROM: embryo osmotic integrity defective early emb || odorant chemosensory response variant || odorant positive chemotaxis defective || egg integrity defective early emb || positive chemotaxis defective |
| ClpP/crotonase | 0.191 | INHERITED FROM: lipid metabolism variant || level of transgene expression variant || organism metabolism processing variant || fat content variant |
| HMG-box | 0.191 | INHERITED FROM: maintenance of gene silencing variant || transgene expression variant || organism metabolism processing variant |
| DBL homology domain (DH-domain) | 0.191 | INHERITED FROM: organism pathogen response variant || pathogen resistance increased || organism environmental stimulus response variant || bacterially unswollen || aldicarb response variant |
| (Trans)glycosidases | 0.2323 | INHERITED FROM: pathogen load variant || pathogen susceptibility increased |
| RNA-binding domain, RBD | 0.2394 | INHERITED FROM: maintenance of gene silencing variant || mRNA export variant || antimicrobial gene expression variant || RNA expression variant || no induction of antimicrobial peptide expression after infection || innate immune response variant || starvation induced apoptosis variant || RNA processing variant || alternative splicing variant || sick || organism metabolism processing variant |
| 6-phosphogluconate dehydrogenase C-terminal domain-like | 0.2596 | INHERITED FROM: lipid metabolism variant || fat content variant |
| Bromodomain | 0.2596 | INHERITED FROM: drug adaptation variant || organism UV hypersensitive || anesthetic resistant || ethanol resistant || acute functional tolerance to alcohol defective || sick || anesthetic response variant || organism UV response variant |
| UDP-Glycosyltransferase/glycogen phosphorylase | 0.2654 | INHERITED FROM: organism osmotic stress response variant |
| SNARE-like | 0.2873 | INHERITED FROM: transgene subcellular localization variant || acetylcholinesterase inhibitor response variant || transgene expression variant || pattern of transgene expression variant || protein metabolism variant || sick || aldicarb resistant || organism metabolism processing variant || aldicarb response variant || acetylcholinesterase inhibitor resistant || gene expression variant |
| ABC transporter transmembrane region | 0.2877 | INHERITED FROM: colchicine hypersensitive || metal response variant || organism environmental stimulus response variant || RNAi response variant || cadmium response variant |
| POZ domain | 0.2923 | INHERITED FROM: L1 arrest || chemical hypersensitive || resistant to protein aggregation induced paralysis || protein aggregation induced behavior variant || early larval arrest |
| Cysteine proteinases | 0.297 | INHERITED FROM: osmotic integrity variant || hypoosmotic shock hypersensitive || pattern of transgene expression variant || protein protein interaction variant || organism metabolism processing variant || paraquat hypersensitive || protein interaction variant |
| Lipocalins | 0.2974 | INHERITED FROM: lipid metabolism variant || fat content increased || fat content variant || paraquat hypersensitive |
| Nicotinic receptor ligand binding domain-like | 0.3248 | INHERITED FROM: nicotine resistant || aqueous chemosensory response variant || hypoosmotic shock hypersensitive || mechanosensation variant || antihelmintic response variant || slowing response on food variant || organism environmental stimulus response variant || cholinergic agonist resistant || DMPP response variant || sodium chloride chemotaxis variant || selenium response variant || chemical response variant || drug response variant |
| Ubiquitin-like | 0.3348 | INHERITED FROM: protein aggregation variant || protein protein interaction variant || organism metabolism processing variant || heteroplasmy || protein interaction variant |
| PX domain | 0.3509 | INHERITED FROM: protein expression reduced || protein subcellular localization variant || protein expression variant |
| Translation proteins SH3-like domain | 0.3509 | INHERITED FROM: protein aggregation variant || transgene expression variant || protein protein interaction variant || organism metabolism processing variant || early larval arrest || gene expression variant |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.3528 | INHERITED FROM: nicotine resistant || aqueous chemosensory response variant || hypoosmotic shock hypersensitive || mechanosensation variant || antihelmintic response variant || slowing response on food variant || organism environmental stimulus response variant || cholinergic agonist resistant || positive chemotaxis variant || DMPP response variant || sodium chloride chemotaxis variant || selenium response variant || chemical response variant || drug response variant |
| BRCT domain | 0.3708 | INHERITED FROM: organism ionizing radiation response variant |
| FKBP-like | 0.3844 | INHERITED FROM: protein aggregation variant || transgene subcellular localization variant || pattern of transgene expression variant || protein protein interaction variant || protein interaction variant |
| Galactose-binding domain-like | 0.4478 | INHERITED FROM: protein aggregation variant || protein protein interaction variant || protein interaction variant |
| SH2 domain | 0.4486 | INHERITED FROM: protein expression reduced || level of protein expression variant || protein expression variant |
| Class II aaRS and biotin synthetases | 0.4551 | INHERITED FROM: hypoxia response variant || oxygen response variant || hypoxia resistant || transgene expression variant || organism environmental stimulus response variant || organism metabolism processing variant || gene expression variant |
| RNI-like | 0.4615 | INHERITED FROM: resistant to protein aggregation induced paralysis |
| FYVE/PHD zinc finger | 0.4685 | INHERITED FROM: protein modification variant || organism UV hypersensitive || protein methylation variant || ectopic expression transgene || organism UV response variant |
| DHS-like NAD/FAD-binding domain | 0.4686 | INHERITED FROM: protein acetylation variant || protein modification variant |
| PRTase-like | 0.4686 | INHERITED FROM: Fluorouracil resistant || drug resistant |
| Hect, E3 ligase catalytic domain | 0.4686 | INHERITED FROM: protein aggregation variant || transgene subcellular localization variant || transgene expression variant || organism environmental stimulus response variant || pattern of transgene expression variant || protein protein interaction variant || organism metabolism processing variant || protein aggregation induced behavior variant || gene expression variant || protein interaction variant |
| Myosin rod fragments | 0.4686 | INHERITED FROM: drug resistant |
| Voltage-gated potassium channels | 0.4757 | INHERITED FROM: adrenergic receptor antagonist response variant || serotonin resistant || mechanosensation variant || protein metabolism variant || protein degradation variant || serotonin response variant || growth rate variant || positive chemotaxis defective |
| Calpain large subunit, middle domain (domain III) | 0.517 | INHERITED FROM: metabolic pathway variant || protein metabolism variant || protein degradation variant |
| Ferredoxin reductase-like, C-terminal NADP-linked domain | 0.517 | INHERITED FROM: pattern protein expression variant |
| Riboflavin synthase domain-like | 0.517 | INHERITED FROM: pattern protein expression variant |
| Sm-like ribonucleoproteins | 0.5192 | INHERITED FROM: organism heat response variant || transgene expression variant || pattern of transgene expression variant || sick || protein subcellular localization variant || life span variant || unfolded protein response variant || gene expression variant |
| WW domain | 0.5192 | INHERITED FROM: maintenance of gene silencing variant || aldicarb resistant || acetylcholinesterase inhibitor resistant |
| Cystine-knot cytokines | 0.5192 | INHERITED FROM: nicotine response variant || levamisole response variant |
| Ribosomal protein S5 domain 2-like | 0.5324 | INHERITED FROM: transgene expression variant || early larval arrest |
| SET domain | 0.5533 | INHERITED FROM: maintenance of gene silencing variant || shortened life span || protein modification variant || metabolic pathway variant || protein methylation variant || RNAi response variant || histone methylation variant || protein metabolism variant || life span variant || spontaneous mutation rate increased || somatic transgene silencing variant || ectopic expression antibody || protein expression variant || dosage compensation variant |
| Seven-hairpin glycosidases | 0.5662 | INHERITED FROM: extended life span || protein aggregation variant || protein protein interaction variant |
| Nucleotidylyl transferase | 0.5672 | INHERITED FROM: hypoxia response variant || antimicrobial gene expression variant || oxygen response variant || hypoxia resistant || innate immune response variant || organism environmental stimulus response variant || paraquat resistant || transgene expression increased || organism metabolism processing variant |
| SAM/Pointed domain | 0.5672 | INHERITED FROM: aldicarb response variant |
| UBC-like | 0.5769 | INHERITED FROM: protein aggregation variant || transgene subcellular localization variant || pattern of transgene expression variant || sick || protein protein interaction variant || organism metabolism processing variant || late larval arrest || protein interaction variant |
| FAD/NAD(P)-binding domain | 0.584 | INHERITED FROM: ATP levels variant || pesticide response variant || ATP levels reduced || life span variant |
| FAD-linked reductases, C-terminal domain | 0.5857 | INHERITED FROM: life span variant |
| Multidrug resistance efflux transporter EmrE | 0.5857 | INHERITED FROM: pathogen resistance increased || bacterially unswollen |
| HAD-like | 0.5892 | INHERITED FROM: nicotine hypersensitive |
| Nucleotide-binding domain | 0.623 | INHERITED FROM: extended life span || life span variant |
| KA1-like | 0.623 | INHERITED FROM: RNA expression variant |
| GST C-terminal domain-like | 0.6324 | INHERITED FROM: enzyme activity variant || metal response variant || enzyme activity reduced || organism electrophilic stress hypersensitive || organism environmental stimulus response variant || cadmium hypersensitive || organism heat hypersensitive || organism stress response variant |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0.6495 | INHERITED FROM: antimicrobial gene expression variant || drug induced gene expression variant || metabolic pathway variant || egg laying serotonin variant || aging variant || organism environmental stimulus response variant || RNAi response variant || nose touch variant || protein subcellular localization variant || drug resistant || chemical response variant || protein expression variant || growth rate variant |
| MFS general substrate transporter | 0.6824 | INHERITED FROM: organism high sodium chloride hypersensitive |
| S15/NS1 RNA-binding domain | 0.6862 | INHERITED FROM: transgene expression increased |
| Frizzled cysteine-rich domain | 0.6862 | INHERITED FROM: transgene expression reduced || antibody staining variant |
| 4Fe-4S ferredoxins | 0.6862 | INHERITED FROM: transgene expression increased || life span variant |
| ADC-like | 0.7544 | INHERITED FROM: protein aggregation variant || metabolic pathway variant || protein metabolism variant || protein protein interaction variant || transgene expression reduced || protein interaction variant |
| MIT domain | 0.7544 | INHERITED FROM: protein aggregation variant || protein protein interaction variant || protein interaction variant |
| Fibronectin type III | 0.7907 | INHERITED FROM: metabolic pathway variant || growth rate variant |
| Leucine zipper domain | 0.8223 | INHERITED FROM: mRNA expression variant || pore forming toxin response variant || level of transgene expression variant || transgene expression reduced || pathogen susceptibility increased || mRNA levels reduced |
| GTPase activation domain, GAP | 0.8283 | INHERITED FROM: protein expression variant |
| Clavaminate synthase-like | 0.8286 | INHERITED FROM: organism temperature response variant || protein methylation variant || histone methylation variant || life span variant |
| Glucocorticoid receptor-like (DNA-binding domain) | 0.8338 | INHERITED FROM: gene expression level high || fat content increased || SDS sensitive dauer || gene expression level reduced || level of transgene expression variant || transgene expression reduced || dauer resistance to harsh conditions variant |
| EF-hand | 0.8417 | INHERITED FROM: protein aggregation variant || protein interaction variant |
| UBA-like | 0.8532 | INHERITED FROM: protein aggregation variant || protein protein interaction variant |
| alpha/beta-Hydrolases | 0.8569 | INHERITED FROM: acetylcholinesterase activity variant || fat content variant || acetylcholinesterase reduced |
| Thioredoxin-like | 0.9063 | INHERITED FROM: enzyme activity variant || enzyme activity reduced || organism electrophilic stress hypersensitive || paraquat response variant || organism environmental stimulus response variant || cadmium hypersensitive || organism heat hypersensitive || organism stress response variant |
| DNA/RNA polymerases | 0.9167 | INHERITED FROM: DNA metabolism variant || DNA repair variant |
| p53-like transcription factors | 0.9211 | INHERITED FROM: ectopic expression transgene || gene expression level reduced |
| Ribonuclease PH domain 2-like | 0.933 | INHERITED FROM: early larval arrest |
| Immunoglobulin | 0.9414 | INHERITED FROM: protein degradation variant || aldicarb response variant || growth rate variant |
| Ribonuclease H-like | 0.9573 | INHERITED FROM: maintenance of gene silencing variant || siRNA expression variant || RNA expression variant || RNAi response variant || RNAi enhanced || 21U RNA expression variant || somatic transgene silencing variant |
| PAZ domain | 0.9695 | INHERITED FROM: maintenance of gene silencing variant || siRNA expression variant || RNA expression variant || mRNA levels increased || RNAi response variant || RNAi enhanced || 21U RNA expression variant || somatic transgene silencing variant |
| Eukaryotic type KH-domain (KH-domain type I) | 0.9782 | INHERITED FROM: RNA expression variant |
| Ligand-binding domain in the NO signalling and Golgi transport | 0.9847 | INHERITED FROM: carbon dioxide response variant || carbon dioxide avoidance variant |
| Cyclophilin-like | 0.9862 | INHERITED FROM: protein aggregation variant || transgene subcellular localization variant || transgene expression variant || pattern of transgene expression variant || protein protein interaction variant || gene expression variant || protein interaction variant |
| CoA-dependent acyltransferases | 0.9862 | INHERITED FROM: lipid metabolism variant |
| F-box domain | 1 | INHERITED FROM: resistant to protein aggregation induced paralysis |
| B-box zinc-binding domain | 1 | INHERITED FROM: protein aggregation variant || transgene subcellular localization variant || transgene expression variant || protein protein interaction variant || organism metabolism processing variant || gene expression variant || protein interaction variant |
| Nuclear receptor ligand-binding domain | 1 | INHERITED FROM: lipid metabolism variant || gene expression level high || fat content increased || SDS sensitive dauer || gene expression level reduced || level of transgene expression variant || transgene expression reduced || dauer resistance to harsh conditions variant |
| Bet v1-like | 1 | INHERITED FROM: growth rate variant |
| Saposin | 1 | INHERITED FROM: pathogen load variant || increased pathogen survival || level of transgene expression variant || transgene expression reduced |
| Snake toxin-like | 1 | INHERITED FROM: fat content reduced |
| Family A G protein-coupled receptor-like | 1 | INHERITED FROM: locomotion rate serotonin variant || serotonin induced pumping variant || male tail curling serotonin variant || serotonin induced fat reduction variant |
| RING/U-box | 1 | INHERITED FROM: protein aggregation variant || transgene subcellular localization variant || transgene expression variant || pattern of transgene expression variant || protein protein interaction variant || organism metabolism processing variant || gene expression variant || protein interaction variant |
| beta-beta-alpha zinc fingers | 1 | INHERITED FROM: inhibitor of serotonin uptake variant || egg laying serotonin resistant || imipramine resistant || egg laying imipramine resistant || organism metabolism processing variant |
| Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
| Second domain of FERM | 0 | Direct |
| Thyroglobulin type-1 domain | 0 | Direct |
| Smc hinge domain | 0 | Direct |
| S-adenosylmethionine synthetase | 0 | Direct |
| Troponin coil-coiled subunits | 0 | Direct |
| Tubby C-terminal domain-like | 0 | Direct |
| Transducin (alpha subunit), insertion domain | 0 | Direct |
| Zn-finger domain of Sec23/24 | 0 | Direct |
| Cdc48 domain 2-like | 0 | Direct |
| Invertebrate chitin-binding proteins | 0 | Direct |
| Elafin-like | 0 | Direct |
| Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | Direct |
| dsRNA-binding domain-like | 0 | Direct |
| BEACH domain | 0 | Direct |
| R3H domain | 0 | Direct |
| Kringle-like | 0 | Direct |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
| Actin-like ATPase domain | 0 | Direct |
| Ribosomal protein L10-like | 0 | Direct |
| Insulin-like | 0 | Direct |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | Direct |
| 2Fe-2S ferredoxin-like | 0 | Direct |
| Protease propeptides/inhibitors | 0 | Direct |
| PK beta-barrel domain-like | 0 | Direct |
| ArfGap/RecO-like zinc finger | 0 | Direct |
| DEATH domain | 0 | Direct |
| Restriction endonuclease-like | 0 | Direct |
| YWTD domain | 0 | Direct |
| YbiA-like | 0 | Direct |
| Carbohydrate phosphatase | 0 | Direct |
| Class II aaRS ABD-related | 0 | Direct |
| PABC (PABP) domain | 0 | Direct |
| Retrovirus zinc finger-like domains | 0 | Direct |
| Galactose oxidase, central domain | 0 | Direct |
| Rudiment single hybrid motif | 0 | Direct |
| Succinyl-CoA synthetase domains | 0 | Direct |
| Mitochondrial carrier | 0 | Direct |
| Fibrinogen C-terminal domain-like | 0 | Direct |
| PEP carboxykinase-like | 0 | Direct |
| Cadherin-like | 0 | Direct |
| cAMP-binding domain-like | 0 | Direct |
| HSP90 C-terminal domain | 0 | Direct |
| Cu,Zn superoxide dismutase-like | 0 | Direct |
| Arginase/deacetylase | 0 | Direct |
| Phoshotransferase/anion transport protein | 0 | Direct |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Profilin (actin-binding protein) | 0 | Direct |
| Translational machinery components | 0 | Direct |
| Complement control module/SCR domain | 0 | Direct |
| Ferritin-like | 0 | Direct |
| AN1-like Zinc finger | 0 | Direct |
| CAD & PB1 domains | 0 | Direct |
| Class I glutamine amidotransferase-like | 0 | Direct |
| SPOC domain-like | 0 | Direct |
| MgtE membrane domain-like | 0 | Direct |
| Citrate synthase | 0 | Direct |
| Isocitrate/Isopropylmalate dehydrogenase-like | 0 | Direct |
| ValRS/IleRS/LeuRS editing domain | 0 | Direct |
| Galactose mutarotase-like | 0 | Direct |
| Phosphoglucomutase, C-terminal domain | 0 | Direct |
| lambda repressor-like DNA-binding domains | 0 | Direct |
| LDH C-terminal domain-like | 0 | Direct |
| RBP11-like subunits of RNA polymerase | 0 | Direct |
| Subdomain of clathrin and coatomer appendage domain | 0 | Direct |
| Band 7/SPFH domain | 0 | Direct |
| Ribulose-phoshate binding barrel | 0 | Direct |
| LysM domain | 0 | Direct |
| Acyl-CoA dehydrogenase NM domain-like | 0 | Direct |
| PreATP-grasp domain | 0 | Direct |
| Thiolase-like | 0 | Direct |
| FF domain | 0 | Direct |
| Terpenoid synthases | 0 | Direct |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
| Subtilisin-like | 0 | Direct |
| GroEL apical domain-like | 0 | Direct |
| ALDH-like | 0 | Direct |
| Tubulin nucleotide-binding domain-like | 0 | Direct |
| PAP/OAS1 substrate-binding domain | 0 | Direct |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | Direct |
| Phosphoglucomutase, first 3 domains | 0 | Direct |
| Hedgehog/intein (Hint) domain | 0 | Direct |
| F1F0 ATP synthase subunit C | 0 | Direct |
| PHM/PNGase F | 0 | Direct |
| Ribosomal L27 protein-like | 0 | Direct |
| ENTH/VHS domain | 0 | Direct |
| CBD9-like | 0 | Direct |
| Chitinase insertion domain | 0 | Direct |
| Creatinase/prolidase N-terminal domain | 0 | Direct |
| SAICAR synthase-like | 0 | Direct |
| FtsH protease domain-like | 0 | Direct |
| Doublecortin (DC) | 0 | Direct |
| Sec1/munc18-like (SM) proteins | 0 | Direct |
| Glutathione synthetase ATP-binding domain-like | 0 | Direct |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
| Formate/glycerate dehydrogenase catalytic domain-like | 0 | Direct |
| SCP-like | 0 | Direct |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | Direct |
| Pepsin inhibitor-3 | 0 | Direct |
| Glycolipid transfer protein, GLTP | 0 | Direct |
| GroEL equatorial domain-like | 0 | Direct |
| Blood coagulation inhibitor (disintegrin) | 0 | Direct |
| Tricorn protease domain 2 | 0 | Direct |
| 14-3-3 protein | 0 | Direct |
| Zn-binding ribosomal proteins | 0 | Direct |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | Direct |
| Pentein | 0 | Direct |
| Periplasmic binding protein-like II | 0 | Direct |
| Sec63 N-terminal domain-like | 0 | Direct |
| Bacterial exopeptidase dimerisation domain | 0 | Direct |
| Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0 | Direct |
| GYF domain | 0 | Direct |
| Polo-box domain | 0 | Direct |
| Purine and uridine phosphorylases | 0 | Direct |
| t-snare proteins | 0 | Direct |
| Chromo domain-like | 0 | Direct |
| Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
| Cation efflux protein cytoplasmic domain-like | 0 | Direct |
| Spectrin repeat | 0 | Direct |
| ARID-like | 0 | Direct |
| Single hybrid motif | 0 | Direct |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | Direct |
| SWIB/MDM2 domain | 0 | Direct |
| 3-carboxy-cis,cis-mucoante lactonizing enzyme | 0 | Direct |
| Helical domain of Sec23/24 | 0 | Direct |
| Phosphoenolpyruvate/pyruvate domain | 0 | Direct |
| CO dehydrogenase molybdoprotein N-domain-like | 0 | Direct |
| Carboxypeptidase regulatory domain-like | 0 | Direct |
| PLC-like phosphodiesterases | 0 | Direct |
| Clathrin adaptor appendage domain | 0 | Direct |
| Outer arm dynein light chain 1 | 0 | Direct |
| Carbon-nitrogen hydrolase | 0 | Direct |
| alpha/beta knot | 0 | Direct |
| Hypothetical protein c14orf129, hspc210 | 0 | Direct |
| Proton glutamate symport protein | 0 | Direct |
| Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | Direct |
| PEBP-like | 0 | Direct |
| MIR domain | 0 | Direct |
| HSP40/DnaJ peptide-binding domain | 0 | Direct |
| Carbonic anhydrase | 0 | Direct |
| Ribosomal protein S10 | 0 | Direct |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
| Nop domain | 0 | Direct |
| MOSC N-terminal domain-like | 0 | Direct |
| CRAL/TRIO N-terminal domain | 0 | Direct |
| Heme-dependent peroxidases | 0 | Direct |
| Lamin A/C globular tail domain | 0 | Direct |
| DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
| LEM domain | 0 | Direct |
| SIS domain | 0 | Direct |
| Integrin domains | 0 | Direct |
| Thiamin diphosphate-binding fold (THDP-binding) | 0 | Direct |
| Putative DNA-binding domain | 0 | Direct |
| TK C-terminal domain-like | 0 | Direct |
| Terpenoid cyclases/Protein prenyltransferases | 0 | Direct |
| Molybdenum cofactor-binding domain | 0 | Direct |
| WGR domain-like | 0 | Direct |
| Cytochrome c | 0 | Direct |
| VPS9 domain | 0 | Direct |
| Cullin homology domain | 0 | Direct |
| Cation efflux protein transmembrane domain-like | 0 | Direct |
| Domain of poly(ADP-ribose) polymerase | 0 | Direct |
| PLP-binding barrel | 0 | Direct |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| beta-lactamase/transpeptidase-like | 0 | Direct |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0 | Direct |
| Cullin repeat-like | 0 | Direct |
| Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | Direct |
| eIF4e-like | 0 | Direct |
| GAS2 domain-like | 0 | Direct |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | Direct |
| Tim10-like | 0 | Direct |
| ThrRS/AlaRS common domain | 0 | Direct |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | Direct |
| Activating enzymes of the ubiquitin-like proteins | 0 | Direct |
| PUA domain-like | 0 | Direct |
| Annexin | 0 | Direct |
| Small-conductance potassium channel | 0 | Direct |
| PurM N-terminal domain-like | 0 | Direct |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
| GroES-like | 0 | Direct |
| MFPT repeat-like | 0 | Direct |
| Acid phosphatase/Vanadium-dependent haloperoxidase | 0 | Direct |
| HSP20-like chaperones | 0 | Direct |
| Rap/Ran-GAP | 0 | Direct |
| HCP-like | 0 | Direct |
| L30e-like | 0 | Direct |
| DNA repair protein MutS, domain III | 0 | Direct |
| Chaperone J-domain | 0 | Direct |
| GAT-like domain | 0 | Direct |
| Radical SAM enzymes | 0 | Direct |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
| Nucleoside diphosphate kinase, NDK | 0 | Direct |
| Integrin alpha N-terminal domain | 0 | Direct |
| Aminoacid dehydrogenase-like, N-terminal domain | 0 | Direct |
| Lipovitellin-phosvitin complex, superhelical domain | 0 | Direct |
| Cystatin/monellin | 0 | Direct |
| SAND domain-like | 0 | Direct |
| Intermediate filament protein, coiled coil region | 0 | Direct |
| Diaminopimelate epimerase-like | 0 | Direct |
| PEP carboxykinase N-terminal domain | 0 | Direct |
| Tubulin C-terminal domain-like | 0 | Direct |
| Ribosomal protein L1 | 0 | Direct |
| L-aspartase-like | 0 | Direct |
| Aldolase | 0 | Direct |
| Aquaporin-like | 0 | Direct |
| Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | Direct |
| Skp1 dimerisation domain-like | 0 | Direct |
| alpha-catenin/vinculin-like | 0 | Direct |
| CO dehydrogenase ISP C-domain like | 0 | Direct |
| ADP-ribosylation | 0 | Direct |
| Nucleotidyltransferase | 0 | Direct |
| NagB/RpiA/CoA transferase-like | 0 | Direct |
| TGS-like | 0 | Direct |
| PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | Direct |
| Families 57/38 glycoside transferase middle domain | 0 | Direct |
| PYP-like sensor domain (PAS domain) | 0 | Direct |
| Surp module (SWAP domain) | 0 | Direct |
| Ran binding protein zinc finger-like | 0 | Direct |
| PIN domain-like | 0 | Direct |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
| Sec7 domain | 0 | Direct |
| GroEL-intermediate domain like | 0 | Direct |
| Hormone receptor domain | 0 | Direct |
| Composite domain of metallo-dependent hydrolases | 0 | Direct |
| Nucleoporin domain | 0 | Direct |
| Clc chloride channel | 0 | Direct |
| Ribokinase-like | 0 | Direct |
| ISP domain | 0 | Direct |
| Ribosomal proteins S24e, L23 and L15e | 0 | Direct |
| FAD-dependent thiol oxidase | 0 | Direct |
| PurM C-terminal domain-like | 0 | Direct |
| Heme-dependent catalase-like | 0 | Direct |
| WWE domain | 0 | Direct |
| Transducin (heterotrimeric G protein), gamma chain | 0 | Direct |
| Oxysterol-binding protein-like | 0 | Direct |
| DNA ligase/mRNA capping enzyme, catalytic domain | 0 | Direct |
| JAB1/MPN domain | 0 | Direct |
| PGBD-like | 0 | Direct |
| SMAD MH1 domain | 0 | Direct |
| P-loop containing nucleoside triphosphate hydrolases | 0.0000008853 | Direct |
| PH domain-like | 0.00003915 | Direct |
| Histone-fold | 0.0001013 | Direct |
| Periplasmic binding protein-like I | 0.01652 | Inherited |
| TPR-like | 0.01748 | Inherited |
| Protein kinase-like (PK-like) | 0.025 | Inherited |
| ARM repeat | 0.03364 | Inherited |
| PapD-like | 0.03378 | Inherited |
| Homeodomain-like | 0.03578 | Inherited |
| WD40 repeat-like | 0.0421 | Inherited |
| PDZ domain-like | 0.04527 | Inherited |
| Nucleic acid-binding proteins | 0.05767 | Inherited |
| Calponin-homology domain, CH-domain | 0.06018 | Inherited |
| Acetyl-CoA synthetase-like | 0.06698 | Inherited |
| Cyclin-like | 0.06698 | Inherited |
| "Winged helix" DNA-binding domain | 0.06992 | Inherited |
| CCCH zinc finger | 0.07443 | Inherited |
| Translation proteins | 0.09202 | Inherited |
| Nucleotide cyclase | 0.1127 | Inherited |
| HLH, helix-loop-helix DNA-binding domain | 0.1127 | Inherited |
| SMAD/FHA domain | 0.1136 | Inherited |
| Calcium ATPase, transmembrane domain M | 0.1261 | Inherited |
| Ankyrin repeat | 0.1275 | Inherited |
| Regulator of G-protein signaling, RGS | 0.1401 | Inherited |
| Metal cation-transporting ATPase, ATP-binding domain N | 0.1401 | Inherited |
| Cytochrome P450 | 0.1452 | Inherited |
| SH3-domain | 0.1477 | Inherited |
| E set domains | 0.1522 | Inherited |
| Calcium ATPase, transduction domain A | 0.1554 | Inherited |
| Acid proteases | 0.1554 | Inherited |
| EGF/Laminin | 0.1652 | Inherited |
| Cysteine-rich domain | 0.1712 | Inherited |
| Quinoprotein alcohol dehydrogenase-like | 0.1723 | Inherited |
| Multidrug efflux transporter AcrB transmembrane domain | 0.1858 | Inherited |
| ClpP/crotonase | 0.191 | Inherited |
| HMG-box | 0.191 | Inherited |
| DBL homology domain (DH-domain) | 0.191 | Inherited |
| (Trans)glycosidases | 0.2323 | Inherited |
| RNA-binding domain, RBD | 0.2394 | Inherited |
| 6-phosphogluconate dehydrogenase C-terminal domain-like | 0.2596 | Inherited |
| Bromodomain | 0.2596 | Inherited |
| UDP-Glycosyltransferase/glycogen phosphorylase | 0.2654 | Inherited |
| SNARE-like | 0.2873 | Inherited |
| ABC transporter transmembrane region | 0.2877 | Inherited |
| POZ domain | 0.2923 | Inherited |
| Cysteine proteinases | 0.297 | Inherited |
| Lipocalins | 0.2974 | Inherited |
| Nicotinic receptor ligand binding domain-like | 0.3248 | Inherited |
| Ubiquitin-like | 0.3348 | Inherited |
| PX domain | 0.3509 | Inherited |
| Translation proteins SH3-like domain | 0.3509 | Inherited |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.3528 | Inherited |
| BRCT domain | 0.3708 | Inherited |
| FKBP-like | 0.3844 | Inherited |
| Galactose-binding domain-like | 0.4478 | Inherited |
| SH2 domain | 0.4486 | Inherited |
| Class II aaRS and biotin synthetases | 0.4551 | Inherited |
| RNI-like | 0.4615 | Inherited |
| FYVE/PHD zinc finger | 0.4685 | Inherited |
| DHS-like NAD/FAD-binding domain | 0.4686 | Inherited |
| PRTase-like | 0.4686 | Inherited |
| Hect, E3 ligase catalytic domain | 0.4686 | Inherited |
| Myosin rod fragments | 0.4686 | Inherited |
| Voltage-gated potassium channels | 0.4757 | Inherited |
| Calpain large subunit, middle domain (domain III) | 0.517 | Inherited |
| Ferredoxin reductase-like, C-terminal NADP-linked domain | 0.517 | Inherited |
| Riboflavin synthase domain-like | 0.517 | Inherited |
| Sm-like ribonucleoproteins | 0.5192 | Inherited |
| WW domain | 0.5192 | Inherited |
| Cystine-knot cytokines | 0.5192 | Inherited |
| Ribosomal protein S5 domain 2-like | 0.5324 | Inherited |
| SET domain | 0.5533 | Inherited |
| Seven-hairpin glycosidases | 0.5662 | Inherited |
| Nucleotidylyl transferase | 0.5672 | Inherited |
| SAM/Pointed domain | 0.5672 | Inherited |
| UBC-like | 0.5769 | Inherited |
| FAD/NAD(P)-binding domain | 0.584 | Inherited |
| FAD-linked reductases, C-terminal domain | 0.5857 | Inherited |
| Multidrug resistance efflux transporter EmrE | 0.5857 | Inherited |
| HAD-like | 0.5892 | Inherited |
| Nucleotide-binding domain | 0.623 | Inherited |
| KA1-like | 0.623 | Inherited |
| GST C-terminal domain-like | 0.6324 | Inherited |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0.6495 | Inherited |
| MFS general substrate transporter | 0.6824 | Inherited |
| S15/NS1 RNA-binding domain | 0.6862 | Inherited |
| Frizzled cysteine-rich domain | 0.6862 | Inherited |
| 4Fe-4S ferredoxins | 0.6862 | Inherited |
| ADC-like | 0.7544 | Inherited |
| MIT domain | 0.7544 | Inherited |
| Fibronectin type III | 0.7907 | Inherited |
| Leucine zipper domain | 0.8223 | Inherited |
| GTPase activation domain, GAP | 0.8283 | Inherited |
| Clavaminate synthase-like | 0.8286 | Inherited |
| Glucocorticoid receptor-like (DNA-binding domain) | 0.8338 | Inherited |
| EF-hand | 0.8417 | Inherited |
| UBA-like | 0.8532 | Inherited |
| alpha/beta-Hydrolases | 0.8569 | Inherited |
| Thioredoxin-like | 0.9063 | Inherited |
| DNA/RNA polymerases | 0.9167 | Inherited |
| p53-like transcription factors | 0.9211 | Inherited |
| Ribonuclease PH domain 2-like | 0.933 | Inherited |
| Immunoglobulin | 0.9414 | Inherited |
| Ribonuclease H-like | 0.9573 | Inherited |
| PAZ domain | 0.9695 | Inherited |
| Eukaryotic type KH-domain (KH-domain type I) | 0.9782 | Inherited |
| Ligand-binding domain in the NO signalling and Golgi transport | 0.9847 | Inherited |
| Cyclophilin-like | 0.9862 | Inherited |
| CoA-dependent acyltransferases | 0.9862 | Inherited |
| F-box domain | 1 | Inherited |
| B-box zinc-binding domain | 1 | Inherited |
| Nuclear receptor ligand-binding domain | 1 | Inherited |
| Bet v1-like | 1 | Inherited |
| Saposin | 1 | Inherited |
| Snake toxin-like | 1 | Inherited |
| Family A G protein-coupled receptor-like | 1 | Inherited |
| RING/U-box | 1 | Inherited |
| beta-beta-alpha zinc fingers | 1 | Inherited |
(show details)
Supra-domains annotated to this WP term (Not in SPWP)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
53067,100920
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
47220,47220
47220 - alpha-catenin/vinculin-like
47220 - alpha-catenin/vinculin-like | 0 | DIRECT |
55394,55394
55394 - Bactericidal permeability-increasing protein, BPI
55394 - Bactericidal permeability-increasing protein, BPI | 0 | DIRECT |
57196,63825
57196 - EGF/Laminin
63825 - YWTD domain | 0 | DIRECT |
52743,49785
52743 - Subtilisin-like
49785 - Galactose-binding domain-like | 0 | DIRECT |
55326,56042
55326 - PurM N-terminal domain-like
56042 - PurM C-terminal domain-like | 0 | DIRECT |
56112,82615
56112 - Protein kinase-like (PK-like)
82615 - Polo-box domain | 0 | DIRECT |
53738,53738
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains | 0 | DIRECT |
100920,100934
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
52283,51735
52283 - Formate/glycerate dehydrogenase catalytic domain-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
50156,50044
50156 - PDZ domain-like
50044 - SH3-domain | 0 | DIRECT |
54236,54236
54236 - Ubiquitin-like
54236 - Ubiquitin-like | 0 | DIRECT |
56091,50249
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
51905,56425
51905 - FAD/NAD(P)-binding domain
56425 - Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | DIRECT |
53901,53901
53901 - Thiolase-like
53901 - Thiolase-like | 0 | DIRECT |
50447,50465
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
56968,48431
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
48431 - Lipovitellin-phosvitin complex, superhelical domain | 0 | DIRECT |
55973,55973
55973 - S-adenosylmethionine synthetase
55973 - S-adenosylmethionine synthetase | 0 | DIRECT |
52113,52113
52113 - BRCT domain
52113 - BRCT domain | 0 | DIRECT |
161093,161093
161093 - MgtE membrane domain-like
161093 - MgtE membrane domain-like | 0 | DIRECT |
54849,52029
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0 | DIRECT |
56601,48403
56601 - beta-lactamase/transpeptidase-like
48403 - Ankyrin repeat | 0 | DIRECT |
52440,56059
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like | 0 | DIRECT |
64593,74853
64593 - Intermediate filament protein, coiled coil region
74853 - Lamin A/C globular tail domain | 0 | DIRECT |
52540,46785
52540 - P-loop containing nucleoside triphosphate hydrolases
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
48371,56112
48371 - ARM repeat
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
50044,52540
50044 - SH3-domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
56059,51246
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 0 | DIRECT |
75632,46785
75632 - Cullin homology domain
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
47587,56399
47587 - Domain of poly(ADP-ribose) polymerase
56399 - ADP-ribosylation | 0 | DIRECT |
57889,50729
57889 - Cysteine-rich domain
50729 - PH domain-like | 0 | DIRECT |
48065,50729
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like | 0 | DIRECT |
52490,55307
52490 - Tubulin nucleotide-binding domain-like
55307 - Tubulin C-terminal domain-like | 0 | DIRECT |
51971,54373
51971 - Nucleotide-binding domain
54373 - FAD-linked reductases, C-terminal domain | 0 | DIRECT |
55729,55729
55729 - Acyl-CoA N-acyltransferases (Nat)
55729 - Acyl-CoA N-acyltransferases (Nat) | 0 | DIRECT |
57889,48350
57889 - Cysteine-rich domain
48350 - GTPase activation domain, GAP | 0 | DIRECT |
54292,47741
54292 - 2Fe-2S ferredoxin-like
47741 - CO dehydrogenase ISP C-domain like | 0 | DIRECT |
50129,51735
50129 - GroES-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
55681,52954
55681 - Class II aaRS and biotin synthetases
52954 - Class II aaRS ABD-related | 0 | DIRECT |
57625,57625
57625 - Invertebrate chitin-binding proteins
57625 - Invertebrate chitin-binding proteins | 0 | DIRECT |
49348,55711
49348 - Clathrin adaptor appendage domain
55711 - Subdomain of clathrin and coatomer appendage domain | 0 | DIRECT |
50044,50044
50044 - SH3-domain
50044 - SH3-domain | 0 | DIRECT |
46938,52087
46938 - CRAL/TRIO N-terminal domain
52087 - CRAL/TRIO domain | 0 | DIRECT |
54897,52743
54897 - Protease propeptides/inhibitors
52743 - Subtilisin-like | 0 | DIRECT |
82895,82895
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat | 0 | DIRECT |
50692,54585
50692 - ADC-like
54585 - Cdc48 domain 2-like | 0 | DIRECT |
47090,55486
47090 - PGBD-like
55486 - Metalloproteases ("zincins"), catalytic domain | 0 | DIRECT |
57196,57184
57196 - EGF/Laminin
57184 - Growth factor receptor domain | 0 | DIRECT |
81811,82754
81811 - Helical domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
57889,57889
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0 | DIRECT |
52047,52047
52047 - RNI-like
52047 - RNI-like | 0 | DIRECT |
52540,140990
52540 - P-loop containing nucleoside triphosphate hydrolases
140990 - FtsH protease domain-like | 0 | DIRECT |
57184,57196
57184 - Growth factor receptor domain
57196 - EGF/Laminin | 0 | DIRECT |
49562,48371
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat | 0 | DIRECT |
81333,81333
81333 - F1F0 ATP synthase subunit C
81333 - F1F0 ATP synthase subunit C | 0 | DIRECT |
55785,55785
55785 - PYP-like sensor domain (PAS domain)
55785 - PYP-like sensor domain (PAS domain) | 0 | DIRECT |
49742,49742
49742 - PHM/PNGase F
49742 - PHM/PNGase F | 0 | DIRECT |
56645,47203
56645 - Acyl-CoA dehydrogenase NM domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
82919,53300
82919 - Zn-finger domain of Sec23/24
53300 - vWA-like | 0 | DIRECT |
48371,48371
48371 - ARM repeat
48371 - ARM repeat | 0 | DIRECT |
54585,52540
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
48403,52151
48403 - Ankyrin repeat
52151 - FabD/lysophospholipase-like | 0 | DIRECT |
51445,54556
51445 - (Trans)glycosidases
54556 - Chitinase insertion domain | 0 | DIRECT |
51735,56327
51735 - NAD(P)-binding Rossmann-fold domains
56327 - LDH C-terminal domain-like | 0 | DIRECT |
48179,48179
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | DIRECT |
46966,46966
46966 - Spectrin repeat
46966 - Spectrin repeat | 0 | DIRECT |
47203,47203
47203 - Acyl-CoA dehydrogenase C-terminal domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
88713,88688
88713 - Glycoside hydrolase/deacetylase
88688 - Families 57/38 glycoside transferase middle domain | 0 | DIRECT |
57196,49899
57196 - EGF/Laminin
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
54897,53187
54897 - Protease propeptides/inhibitors
53187 - Zn-dependent exopeptidases | 0 | DIRECT |
57903,82199
57903 - FYVE/PHD zinc finger
82199 - SET domain | 0 | DIRECT |
51735,55347
51735 - NAD(P)-binding Rossmann-fold domains
55347 - Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | DIRECT |
51556,51338
51556 - Metallo-dependent hydrolases
51338 - Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
52540,90123
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region | 0 | DIRECT |
47576,47576
47576 - Calponin-homology domain, CH-domain
47576 - Calponin-homology domain, CH-domain | 0 | DIRECT |
144232,82199
144232 - HIT/MYND zinc finger-like
82199 - SET domain | 0 | DIRECT |
54495,46934
54495 - UBC-like
46934 - UBA-like | 0 | DIRECT |
54001,49758
54001 - Cysteine proteinases
49758 - Calpain large subunit, middle domain (domain III) | 0 | DIRECT |
50729,56112
50729 - PH domain-like
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
68923,53795
68923 - PEP carboxykinase N-terminal domain
53795 - PEP carboxykinase-like | 0 | DIRECT |
54534,54534
54534 - FKBP-like
54534 - FKBP-like | 0 | DIRECT |
54768,54768
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like | 0 | DIRECT |
51338,51556
51338 - Composite domain of metallo-dependent hydrolases
51556 - Metallo-dependent hydrolases | 0 | DIRECT |
57756,57756
57756 - Retrovirus zinc finger-like domains
57756 - Retrovirus zinc finger-like domains | 0 | DIRECT |
53738,55957
53738 - Phosphoglucomutase, first 3 domains
55957 - Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
47954,47954
47954 - Cyclin-like
47954 - Cyclin-like | 0 | DIRECT |
81698,81698
81698 - FF domain
81698 - FF domain | 0 | DIRECT |
81631,55003
81631 - PAP/OAS1 substrate-binding domain
55003 - PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | DIRECT |
48464,89009
48464 - ENTH/VHS domain
89009 - GAT-like domain | 0 | DIRECT |
52518,52922
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52922 - TK C-terminal domain-like | 0 | DIRECT |
47895,52540
47895 - Transducin (alpha subunit), insertion domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
50677,52374
50677 - ValRS/IleRS/LeuRS editing domain
52374 - Nucleotidylyl transferase | 0 | DIRECT |
57362,57362
57362 - BPTI-like
57362 - BPTI-like | 0 | DIRECT |
74650,51445
74650 - Galactose mutarotase-like
51445 - (Trans)glycosidases | 0 | DIRECT |
141673,50800
141673 - MOSC N-terminal domain-like
50800 - PK beta-barrel domain-like | 0 | DIRECT |
51905,55424
51905 - FAD/NAD(P)-binding domain
55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | DIRECT |
51695,49562
51695 - PLC-like phosphodiesterases
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
56059,52210
56059 - Glutathione synthetase ATP-binding domain-like
52210 - Succinyl-CoA synthetase domains | 0 | DIRECT |
47741,56176
47741 - CO dehydrogenase ISP C-domain like
56176 - FAD-binding/transporter-associated domain-like | 0 | DIRECT |
55486,57552
55486 - Metalloproteases ("zincins"), catalytic domain
57552 - Blood coagulation inhibitor (disintegrin) | 0 | DIRECT |
54236,47031
54236 - Ubiquitin-like
47031 - Second domain of FERM | 0 | DIRECT |
57184,57184
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | DIRECT |
57850,117839
57850 - RING/U-box
117839 - WWE domain | 0 | DIRECT |
100950,100950
100950 - NagB/RpiA/CoA transferase-like
100950 - NagB/RpiA/CoA transferase-like | 0 | DIRECT |
82615,82615
82615 - Polo-box domain
82615 - Polo-box domain | 0 | DIRECT |
57535,57535
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | DIRECT |
48425,50729
48425 - Sec7 domain
50729 - PH domain-like | 0 | DIRECT |
81301,81631
81301 - Nucleotidyltransferase
81631 - PAP/OAS1 substrate-binding domain | 0 | DIRECT |
54211,55060
54211 - Ribosomal protein S5 domain 2-like
55060 - GHMP Kinase, C-terminal domain | 0 | DIRECT |
53187,49464
53187 - Zn-dependent exopeptidases
49464 - Carboxypeptidase regulatory domain-like | 0 | DIRECT |
46785,46785
46785 - "Winged helix" DNA-binding domain
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
161111,160240
161111 - Cation efflux protein transmembrane domain-like
160240 - Cation efflux protein cytoplasmic domain-like | 0 | DIRECT |
55874,54211
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
54211 - Ribosomal protein S5 domain 2-like | 0 | DIRECT |
57903,51197
57903 - FYVE/PHD zinc finger
51197 - Clavaminate synthase-like | 0 | DIRECT |
50249,50249
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
52540,47917
52540 - P-loop containing nucleoside triphosphate hydrolases
47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
55486,50923
55486 - Metalloproteases ("zincins"), catalytic domain
50923 - Hemopexin-like domain | 0 | DIRECT |
81324,53850
81324 - Voltage-gated potassium channels
53850 - Periplasmic binding protein-like II | 0 | DIRECT |
47769,47769
47769 - SAM/Pointed domain
47769 - SAM/Pointed domain | 0 | DIRECT |
54665,56003
54665 - CO dehydrogenase molybdoprotein N-domain-like
56003 - Molybdenum cofactor-binding domain | 0 | DIRECT |
50978,50998
50978 - WD40 repeat-like
50998 - Quinoprotein alcohol dehydrogenase-like | 0 | DIRECT |
48334,52540
48334 - DNA repair protein MutS, domain III
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
81383,50978
81383 - F-box domain
50978 - WD40 repeat-like | 0 | DIRECT |
57863,48403
57863 - ArfGap/RecO-like zinc finger
48403 - Ankyrin repeat | 0 | DIRECT |
55920,46785
55920 - Creatinase/aminopeptidase
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
53067,53067
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 0 | DIRECT |
54160,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
54695,81382
54695 - POZ domain
81382 - Skp1 dimerisation domain-like | 0 | DIRECT |
49493,49493
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
48431,56968
48431 - Lipovitellin-phosvitin complex, superhelical domain
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | DIRECT |
57938,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
50729,47473
50729 - PH domain-like
47473 - EF-hand | 0 | DIRECT |
81324,81296
81324 - Voltage-gated potassium channels
81296 - E set domains | 0 | DIRECT |
64356,49447
64356 - SNARE-like
49447 - Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
56672,100879
56672 - DNA/RNA polymerases
100879 - Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
81324,81327
81324 - Voltage-gated potassium channels
81327 - Small-conductance potassium channel | 0 | DIRECT |
52540,81271
52540 - P-loop containing nucleoside triphosphate hydrolases
81271 - TGS-like | 0 | DIRECT |
51206,51206
51206 - cAMP-binding domain-like
51206 - cAMP-binding domain-like | 0 | DIRECT |
57414,57414
57414 - Hairpin loop containing domain-like
57414 - Hairpin loop containing domain-like | 0 | DIRECT |
90229,90229
90229 - CCCH zinc finger
90229 - CCCH zinc finger | 0 | DIRECT |
51445,51011
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain | 0 | DIRECT |
141739,141739
141739 - MFPT repeat-like
141739 - MFPT repeat-like | 0 | DIRECT |
47473,51695
47473 - EF-hand
51695 - PLC-like phosphodiesterases | 0 | DIRECT |
52374,47323
52374 - Nucleotidylyl transferase
47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
81383,52047
81383 - F-box domain
52047 - RNI-like | 0 | DIRECT |
74788,75632
74788 - Cullin repeat-like
75632 - Cullin homology domain | 0 | DIRECT |
47031,50729
47031 - Second domain of FERM
50729 - PH domain-like | 0 | DIRECT |
47473,103506
47473 - EF-hand
103506 - Mitochondrial carrier | 0 | DIRECT |
52518,52518
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52518 - Thiamin diphosphate-binding fold (THDP-binding) | 0 | DIRECT |
49265,48726
49265 - Fibronectin type III
48726 - Immunoglobulin | 0 | DIRECT |
49313,49313
49313 - Cadherin-like
49313 - Cadherin-like | 0 | DIRECT |
53187,55031
53187 - Zn-dependent exopeptidases
55031 - Bacterial exopeptidase dimerisation domain | 0 | DIRECT |
48592,54849
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like | 0 | DIRECT |
47413,46689
47413 - lambda repressor-like DNA-binding domains
46689 - Homeodomain-like | 0 | DIRECT |
54160,54160
54160 - Chromo domain-like
54160 - Chromo domain-like | 0 | DIRECT |
52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.07747 | INHERITED FROM: organism UV hypersensitive || sick || dauer arrest variant || dauer lifespan variant || dauer lifespan extended || organism hypersensitive ionizing radiation || organism UV response variant || organism stress response variant |
48452,48452
48452 - TPR-like
48452 - TPR-like | 0.1136 | INHERITED FROM: ivermectin resistant || ivermectin response variant || aqueous chemosensory response variant || antihelmintic response variant || dauer defective || organism environmental stimulus response variant || pattern of transgene expression variant || chemical response variant || gene expression variant || positive chemotaxis defective |
56112,55073
56112 - Protein kinase-like (PK-like)
55073 - Nucleotide cyclase | 0.1401 | INHERITED FROM: iodide chemotaxis variant || AWC odorant chemotaxis variant || benzaldehyde chemotaxis variant || aqueous chemosensory response variant || chemotaxis variant || AWC odorant chemotaxis defective || lithium chemotaxis defective || alkaline pH chemotaxis variant || bromide chemotaxis variant || anion positive chemotaxis variant || organism environmental stimulus response variant || chemosensory response variant || anion positive chemotaxis defective || iodide chemotaxis defective || positive chemotaxis variant || magnesium chemotaxis defective || cation positive chemotaxis variant || cation positive chemotaxis defective || chemical response variant || bromide chemotaxis defective |
81660,56784
81660 - Metal cation-transporting ATPase, ATP-binding domain N
56784 - HAD-like | 0.1401 | INHERITED FROM: organism environmental stimulus response variant || drug hypersensitive || nicotine hypersensitive || lipid composition variant |
52540,50447
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins | 0.2115 | INHERITED FROM: proteasome core activity variant || protein aggregation variant || protein modification variant || mRNA levels increased || protein phosphorylation increased || transgene expression variant || protein protein interaction variant || mRNA levels reduced |
56436,56436
56436 - C-type lectin-like
56436 - C-type lectin-like | 0.2336 | INHERITED FROM: cadmium hypersensitive |
56436,49854
56436 - C-type lectin-like
49854 - Spermadhesin, CUB domain | 0.2554 | INHERITED FROM: cadmium response variant || cadmium hypersensitive |
51735,48179
51735 - NAD(P)-binding Rossmann-fold domains
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0.2596 | INHERITED FROM: lipid metabolism variant || fat content variant |
56784,81665
56784 - HAD-like
81665 - Calcium ATPase, transmembrane domain M | 0.2596 | INHERITED FROM: organism environmental stimulus response variant || drug hypersensitive || nicotine hypersensitive |
90123,52540
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.2877 | INHERITED FROM: colchicine hypersensitive || metal response variant || organism environmental stimulus response variant || RNAi response variant || cadmium response variant |
52833,52833
52833 - Thioredoxin-like
52833 - Thioredoxin-like | 0.3173 | INHERITED FROM: protein aggregation variant || pattern of transgene expression variant || protein protein interaction variant || protein interaction variant |
50978,50978
50978 - WD40 repeat-like
50978 - WD40 repeat-like | 0.3173 | INHERITED FROM: ivermectin resistant || ivermectin response variant || aqueous chemosensory response variant || chemotaxis variant || pesticide response variant || mechanosensation variant || odorant chemosensory response variant || negative chemotaxis variant || dauer defective || osmotic avoidance variant || aqueous positive chemotaxis variant || positive chemotaxis variant || drug resistant || positive chemotaxis defective || aqueous positive chemotaxis defective |
47473,47473
47473 - EF-hand
47473 - EF-hand | 0.3509 | INHERITED FROM: acetylcholinesterase inhibitor response variant || acetylcholinesterase inhibitor hypersensitive || aldicarb response variant |
63712,90112
63712 - Nicotinic receptor ligand binding domain-like
90112 - Neurotransmitter-gated ion-channel transmembrane pore | 0.3528 | INHERITED FROM: nicotine resistant || aqueous chemosensory response variant || hypoosmotic shock hypersensitive || mechanosensation variant || antihelmintic response variant || slowing response on food variant || organism environmental stimulus response variant || cholinergic agonist resistant || positive chemotaxis variant || DMPP response variant || sodium chloride chemotaxis variant || selenium response variant || chemical response variant || drug response variant |
54928,54928
54928 - RNA-binding domain, RBD
54928 - RNA-binding domain, RBD | 0.3708 | INHERITED FROM: starvation induced apoptosis variant || late larval arrest || gene expression variant || organism starvation response variant |
52833,47616
52833 - Thioredoxin-like
47616 - GST C-terminal domain-like | 0.4664 | INHERITED FROM: enzyme activity variant || metal response variant || enzyme activity reduced || organism electrophilic stress hypersensitive || paraquat response variant || organism environmental stimulus response variant || cadmium hypersensitive || organism heat hypersensitive || organism stress response variant |
48403,48403
48403 - Ankyrin repeat
48403 - Ankyrin repeat | 0.4686 | INHERITED FROM: organism environmental stimulus response variant |
57716,57716
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0.4851 | INHERITED FROM: protein expression reduced || organism metabolism processing variant || protein expression variant |
50044,55550
50044 - SH3-domain
55550 - SH2 domain | 0.5662 | INHERITED FROM: protein expression reduced |
101690,53098
101690 - PAZ domain
53098 - Ribonuclease H-like | 0.5662 | INHERITED FROM: maintenance of gene silencing variant || RNA expression variant || RNAi response variant || 21U RNA expression variant || gene expression variant |
51045,51045
51045 - WW domain
51045 - WW domain | 0.623 | INHERITED FROM: transgene expression variant |
63380,52343
63380 - Riboflavin synthase domain-like
52343 - Ferredoxin reductase-like, C-terminal NADP-linked domain | 0.623 | INHERITED FROM: transgene subcellular localization variant |
57424,57424
57424 - LDL receptor-like module
57424 - LDL receptor-like module | 0.661 | INHERITED FROM: protein expression reduced |
57903,57903
57903 - FYVE/PHD zinc finger
57903 - FYVE/PHD zinc finger | 0.6862 | INHERITED FROM: organism UV hypersensitive || organism environmental stimulus response variant || organism UV response variant |
50249,55681
50249 - Nucleic acid-binding proteins
55681 - Class II aaRS and biotin synthetases | 0.6862 | INHERITED FROM: transgene expression increased |
57716,48508
57716 - Glucocorticoid receptor-like (DNA-binding domain)
48508 - Nuclear receptor ligand-binding domain | 0.7214 | INHERITED FROM: SDS sensitive dauer || chemical hypersensitive || dauer resistance to harsh conditions variant |
57196,57196
57196 - EGF/Laminin
57196 - EGF/Laminin | 0.7291 | INHERITED FROM: protein expression reduced |
51905,54373
51905 - FAD/NAD(P)-binding domain
54373 - FAD-linked reductases, C-terminal domain | 0.7403 | INHERITED FROM: shortened life span || life span variant |
55550,50044
55550 - SH2 domain
50044 - SH3-domain | 0.7544 | INHERITED FROM: protein expression reduced || level of protein expression variant || protein expression variant |
48726,49265
48726 - Immunoglobulin
49265 - Fibronectin type III | 0.8362 | INHERITED FROM: aldicarb resistant || protein degradation variant || chemical response variant || growth rate variant |
48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin | 0.8801 | INHERITED FROM: protein degradation variant || growth rate variant |
54211,55666
54211 - Ribosomal protein S5 domain 2-like
55666 - Ribonuclease PH domain 2-like | 0.933 | INHERITED FROM: early larval arrest |
49785,49785
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like | 0.9376 | INHERITED FROM: protein aggregation variant || protein protein interaction variant || protein interaction variant |
49562,49562
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0.9409 | INHERITED FROM: drug resistant |
57850,57850
57850 - RING/U-box
57850 - RING/U-box | 1 | INHERITED FROM: protein aggregation variant || transgene subcellular localization variant || protein protein interaction variant || protein interaction variant |
53300,56436
53300 - vWA-like
56436 - C-type lectin-like | 1 | INHERITED FROM: pathogen induced death increased || pathogen susceptibility increased |
52777,52777
52777 - CoA-dependent acyltransferases
52777 - CoA-dependent acyltransferases | 1 | INHERITED FROM: lipid metabolism variant || fat content variant |
57850,57845
57850 - RING/U-box
57845 - B-box zinc-binding domain | 1 | INHERITED FROM: protein aggregation variant || transgene subcellular localization variant || protein protein interaction variant || protein interaction variant |
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
53067,100920
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
47220,47220
47220 - alpha-catenin/vinculin-like
47220 - alpha-catenin/vinculin-like | 0 | Direct |
55394,55394
55394 - Bactericidal permeability-increasing protein, BPI
55394 - Bactericidal permeability-increasing protein, BPI | 0 | Direct |
57196,63825
57196 - EGF/Laminin
63825 - YWTD domain | 0 | Direct |
52743,49785
52743 - Subtilisin-like
49785 - Galactose-binding domain-like | 0 | Direct |
55326,56042
55326 - PurM N-terminal domain-like
56042 - PurM C-terminal domain-like | 0 | Direct |
56112,82615
56112 - Protein kinase-like (PK-like)
82615 - Polo-box domain | 0 | Direct |
53738,53738
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains | 0 | Direct |
100920,100934
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
52283,51735
52283 - Formate/glycerate dehydrogenase catalytic domain-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | Direct |
50156,50044
50156 - PDZ domain-like
50044 - SH3-domain | 0 | Direct |
54236,54236
54236 - Ubiquitin-like
54236 - Ubiquitin-like | 0 | Direct |
56091,50249
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins | 0 | Direct |
51905,56425
51905 - FAD/NAD(P)-binding domain
56425 - Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | Direct |
53901,53901
53901 - Thiolase-like
53901 - Thiolase-like | 0 | Direct |
50447,50465
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
56968,48431
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
48431 - Lipovitellin-phosvitin complex, superhelical domain | 0 | Direct |
55973,55973
55973 - S-adenosylmethionine synthetase
55973 - S-adenosylmethionine synthetase | 0 | Direct |
52113,52113
52113 - BRCT domain
52113 - BRCT domain | 0 | Direct |
161093,161093
161093 - MgtE membrane domain-like
161093 - MgtE membrane domain-like | 0 | Direct |
54849,52029
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0 | Direct |
56601,48403
56601 - beta-lactamase/transpeptidase-like
48403 - Ankyrin repeat | 0 | Direct |
52440,56059
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like | 0 | Direct |
64593,74853
64593 - Intermediate filament protein, coiled coil region
74853 - Lamin A/C globular tail domain | 0 | Direct |
52540,46785
52540 - P-loop containing nucleoside triphosphate hydrolases
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
48371,56112
48371 - ARM repeat
56112 - Protein kinase-like (PK-like) | 0 | Direct |
50044,52540
50044 - SH3-domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
56059,51246
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 0 | Direct |
75632,46785
75632 - Cullin homology domain
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
47587,56399
47587 - Domain of poly(ADP-ribose) polymerase
56399 - ADP-ribosylation | 0 | Direct |
57889,50729
57889 - Cysteine-rich domain
50729 - PH domain-like | 0 | Direct |
48065,50729
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like | 0 | Direct |
52490,55307
52490 - Tubulin nucleotide-binding domain-like
55307 - Tubulin C-terminal domain-like | 0 | Direct |
51971,54373
51971 - Nucleotide-binding domain
54373 - FAD-linked reductases, C-terminal domain | 0 | Direct |
55729,55729
55729 - Acyl-CoA N-acyltransferases (Nat)
55729 - Acyl-CoA N-acyltransferases (Nat) | 0 | Direct |
57889,48350
57889 - Cysteine-rich domain
48350 - GTPase activation domain, GAP | 0 | Direct |
54292,47741
54292 - 2Fe-2S ferredoxin-like
47741 - CO dehydrogenase ISP C-domain like | 0 | Direct |
50129,51735
50129 - GroES-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | Direct |
55681,52954
55681 - Class II aaRS and biotin synthetases
52954 - Class II aaRS ABD-related | 0 | Direct |
57625,57625
57625 - Invertebrate chitin-binding proteins
57625 - Invertebrate chitin-binding proteins | 0 | Direct |
49348,55711
49348 - Clathrin adaptor appendage domain
55711 - Subdomain of clathrin and coatomer appendage domain | 0 | Direct |
50044,50044
50044 - SH3-domain
50044 - SH3-domain | 0 | Direct |
46938,52087
46938 - CRAL/TRIO N-terminal domain
52087 - CRAL/TRIO domain | 0 | Direct |
54897,52743
54897 - Protease propeptides/inhibitors
52743 - Subtilisin-like | 0 | Direct |
82895,82895
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat | 0 | Direct |
50692,54585
50692 - ADC-like
54585 - Cdc48 domain 2-like | 0 | Direct |
47090,55486
47090 - PGBD-like
55486 - Metalloproteases ("zincins"), catalytic domain | 0 | Direct |
57196,57184
57196 - EGF/Laminin
57184 - Growth factor receptor domain | 0 | Direct |
81811,82754
81811 - Helical domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
57889,57889
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0 | Direct |
52047,52047
52047 - RNI-like
52047 - RNI-like | 0 | Direct |
52540,140990
52540 - P-loop containing nucleoside triphosphate hydrolases
140990 - FtsH protease domain-like | 0 | Direct |
57184,57196
57184 - Growth factor receptor domain
57196 - EGF/Laminin | 0 | Direct |
49562,48371
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat | 0 | Direct |
81333,81333
81333 - F1F0 ATP synthase subunit C
81333 - F1F0 ATP synthase subunit C | 0 | Direct |
55785,55785
55785 - PYP-like sensor domain (PAS domain)
55785 - PYP-like sensor domain (PAS domain) | 0 | Direct |
49742,49742
49742 - PHM/PNGase F
49742 - PHM/PNGase F | 0 | Direct |
56645,47203
56645 - Acyl-CoA dehydrogenase NM domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
82919,53300
82919 - Zn-finger domain of Sec23/24
53300 - vWA-like | 0 | Direct |
48371,48371
48371 - ARM repeat
48371 - ARM repeat | 0 | Direct |
54585,52540
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
48403,52151
48403 - Ankyrin repeat
52151 - FabD/lysophospholipase-like | 0 | Direct |
51445,54556
51445 - (Trans)glycosidases
54556 - Chitinase insertion domain | 0 | Direct |
51735,56327
51735 - NAD(P)-binding Rossmann-fold domains
56327 - LDH C-terminal domain-like | 0 | Direct |
48179,48179
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | Direct |
46966,46966
46966 - Spectrin repeat
46966 - Spectrin repeat | 0 | Direct |
47203,47203
47203 - Acyl-CoA dehydrogenase C-terminal domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
88713,88688
88713 - Glycoside hydrolase/deacetylase
88688 - Families 57/38 glycoside transferase middle domain | 0 | Direct |
57196,49899
57196 - EGF/Laminin
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
54897,53187
54897 - Protease propeptides/inhibitors
53187 - Zn-dependent exopeptidases | 0 | Direct |
57903,82199
57903 - FYVE/PHD zinc finger
82199 - SET domain | 0 | Direct |
51735,55347
51735 - NAD(P)-binding Rossmann-fold domains
55347 - Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | Direct |
51556,51338
51556 - Metallo-dependent hydrolases
51338 - Composite domain of metallo-dependent hydrolases | 0 | Direct |
52540,90123
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region | 0 | Direct |
47576,47576
47576 - Calponin-homology domain, CH-domain
47576 - Calponin-homology domain, CH-domain | 0 | Direct |
144232,82199
144232 - HIT/MYND zinc finger-like
82199 - SET domain | 0 | Direct |
54495,46934
54495 - UBC-like
46934 - UBA-like | 0 | Direct |
54001,49758
54001 - Cysteine proteinases
49758 - Calpain large subunit, middle domain (domain III) | 0 | Direct |
50729,56112
50729 - PH domain-like
56112 - Protein kinase-like (PK-like) | 0 | Direct |
68923,53795
68923 - PEP carboxykinase N-terminal domain
53795 - PEP carboxykinase-like | 0 | Direct |
54534,54534
54534 - FKBP-like
54534 - FKBP-like | 0 | Direct |
54768,54768
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like | 0 | Direct |
51338,51556
51338 - Composite domain of metallo-dependent hydrolases
51556 - Metallo-dependent hydrolases | 0 | Direct |
57756,57756
57756 - Retrovirus zinc finger-like domains
57756 - Retrovirus zinc finger-like domains | 0 | Direct |
53738,55957
53738 - Phosphoglucomutase, first 3 domains
55957 - Phosphoglucomutase, C-terminal domain | 0 | Direct |
47954,47954
47954 - Cyclin-like
47954 - Cyclin-like | 0 | Direct |
81698,81698
81698 - FF domain
81698 - FF domain | 0 | Direct |
81631,55003
81631 - PAP/OAS1 substrate-binding domain
55003 - PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | Direct |
48464,89009
48464 - ENTH/VHS domain
89009 - GAT-like domain | 0 | Direct |
52518,52922
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52922 - TK C-terminal domain-like | 0 | Direct |
47895,52540
47895 - Transducin (alpha subunit), insertion domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
50677,52374
50677 - ValRS/IleRS/LeuRS editing domain
52374 - Nucleotidylyl transferase | 0 | Direct |
57362,57362
57362 - BPTI-like
57362 - BPTI-like | 0 | Direct |
74650,51445
74650 - Galactose mutarotase-like
51445 - (Trans)glycosidases | 0 | Direct |
141673,50800
141673 - MOSC N-terminal domain-like
50800 - PK beta-barrel domain-like | 0 | Direct |
51905,55424
51905 - FAD/NAD(P)-binding domain
55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | Direct |
51695,49562
51695 - PLC-like phosphodiesterases
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
56059,52210
56059 - Glutathione synthetase ATP-binding domain-like
52210 - Succinyl-CoA synthetase domains | 0 | Direct |
47741,56176
47741 - CO dehydrogenase ISP C-domain like
56176 - FAD-binding/transporter-associated domain-like | 0 | Direct |
55486,57552
55486 - Metalloproteases ("zincins"), catalytic domain
57552 - Blood coagulation inhibitor (disintegrin) | 0 | Direct |
54236,47031
54236 - Ubiquitin-like
47031 - Second domain of FERM | 0 | Direct |
57184,57184
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | Direct |
57850,117839
57850 - RING/U-box
117839 - WWE domain | 0 | Direct |
100950,100950
100950 - NagB/RpiA/CoA transferase-like
100950 - NagB/RpiA/CoA transferase-like | 0 | Direct |
82615,82615
82615 - Polo-box domain
82615 - Polo-box domain | 0 | Direct |
57535,57535
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | Direct |
48425,50729
48425 - Sec7 domain
50729 - PH domain-like | 0 | Direct |
81301,81631
81301 - Nucleotidyltransferase
81631 - PAP/OAS1 substrate-binding domain | 0 | Direct |
54211,55060
54211 - Ribosomal protein S5 domain 2-like
55060 - GHMP Kinase, C-terminal domain | 0 | Direct |
53187,49464
53187 - Zn-dependent exopeptidases
49464 - Carboxypeptidase regulatory domain-like | 0 | Direct |
46785,46785
46785 - "Winged helix" DNA-binding domain
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
161111,160240
161111 - Cation efflux protein transmembrane domain-like
160240 - Cation efflux protein cytoplasmic domain-like | 0 | Direct |
55874,54211
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
54211 - Ribosomal protein S5 domain 2-like | 0 | Direct |
57903,51197
57903 - FYVE/PHD zinc finger
51197 - Clavaminate synthase-like | 0 | Direct |
50249,50249
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins | 0 | Direct |
52540,47917
52540 - P-loop containing nucleoside triphosphate hydrolases
47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
55486,50923
55486 - Metalloproteases ("zincins"), catalytic domain
50923 - Hemopexin-like domain | 0 | Direct |
81324,53850
81324 - Voltage-gated potassium channels
53850 - Periplasmic binding protein-like II | 0 | Direct |
47769,47769
47769 - SAM/Pointed domain
47769 - SAM/Pointed domain | 0 | Direct |
54665,56003
54665 - CO dehydrogenase molybdoprotein N-domain-like
56003 - Molybdenum cofactor-binding domain | 0 | Direct |
50978,50998
50978 - WD40 repeat-like
50998 - Quinoprotein alcohol dehydrogenase-like | 0 | Direct |
48334,52540
48334 - DNA repair protein MutS, domain III
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
81383,50978
81383 - F-box domain
50978 - WD40 repeat-like | 0 | Direct |
57863,48403
57863 - ArfGap/RecO-like zinc finger
48403 - Ankyrin repeat | 0 | Direct |
55920,46785
55920 - Creatinase/aminopeptidase
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
53067,53067
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 0 | Direct |
54160,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
54695,81382
54695 - POZ domain
81382 - Skp1 dimerisation domain-like | 0 | Direct |
49493,49493
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
48431,56968
48431 - Lipovitellin-phosvitin complex, superhelical domain
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | Direct |
57938,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
50729,47473
50729 - PH domain-like
47473 - EF-hand | 0 | Direct |
81324,81296
81324 - Voltage-gated potassium channels
81296 - E set domains | 0 | Direct |
64356,49447
64356 - SNARE-like
49447 - Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
56672,100879
56672 - DNA/RNA polymerases
100879 - Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
81324,81327
81324 - Voltage-gated potassium channels
81327 - Small-conductance potassium channel | 0 | Direct |
52540,81271
52540 - P-loop containing nucleoside triphosphate hydrolases
81271 - TGS-like | 0 | Direct |
51206,51206
51206 - cAMP-binding domain-like
51206 - cAMP-binding domain-like | 0 | Direct |
57414,57414
57414 - Hairpin loop containing domain-like
57414 - Hairpin loop containing domain-like | 0 | Direct |
90229,90229
90229 - CCCH zinc finger
90229 - CCCH zinc finger | 0 | Direct |
51445,51011
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain | 0 | Direct |
141739,141739
141739 - MFPT repeat-like
141739 - MFPT repeat-like | 0 | Direct |
47473,51695
47473 - EF-hand
51695 - PLC-like phosphodiesterases | 0 | Direct |
52374,47323
52374 - Nucleotidylyl transferase
47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
81383,52047
81383 - F-box domain
52047 - RNI-like | 0 | Direct |
74788,75632
74788 - Cullin repeat-like
75632 - Cullin homology domain | 0 | Direct |
47031,50729
47031 - Second domain of FERM
50729 - PH domain-like | 0 | Direct |
47473,103506
47473 - EF-hand
103506 - Mitochondrial carrier | 0 | Direct |
52518,52518
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52518 - Thiamin diphosphate-binding fold (THDP-binding) | 0 | Direct |
49265,48726
49265 - Fibronectin type III
48726 - Immunoglobulin | 0 | Direct |
49313,49313
49313 - Cadherin-like
49313 - Cadherin-like | 0 | Direct |
53187,55031
53187 - Zn-dependent exopeptidases
55031 - Bacterial exopeptidase dimerisation domain | 0 | Direct |
48592,54849
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like | 0 | Direct |
47413,46689
47413 - lambda repressor-like DNA-binding domains
46689 - Homeodomain-like | 0 | Direct |
54160,54160
54160 - Chromo domain-like
54160 - Chromo domain-like | 0 | Direct |
52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.07747 | Inherited |
48452,48452
48452 - TPR-like
48452 - TPR-like | 0.1136 | Inherited |
56112,55073
56112 - Protein kinase-like (PK-like)
55073 - Nucleotide cyclase | 0.1401 | Inherited |
81660,56784
81660 - Metal cation-transporting ATPase, ATP-binding domain N
56784 - HAD-like | 0.1401 | Inherited |
52540,50447
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins | 0.2115 | Inherited |
56436,56436
56436 - C-type lectin-like
56436 - C-type lectin-like | 0.2336 | Inherited |
56436,49854
56436 - C-type lectin-like
49854 - Spermadhesin, CUB domain | 0.2554 | Inherited |
51735,48179
51735 - NAD(P)-binding Rossmann-fold domains
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0.2596 | Inherited |
56784,81665
56784 - HAD-like
81665 - Calcium ATPase, transmembrane domain M | 0.2596 | Inherited |
90123,52540
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.2877 | Inherited |
52833,52833
52833 - Thioredoxin-like
52833 - Thioredoxin-like | 0.3173 | Inherited |
50978,50978
50978 - WD40 repeat-like
50978 - WD40 repeat-like | 0.3173 | Inherited |
47473,47473
47473 - EF-hand
47473 - EF-hand | 0.3509 | Inherited |
63712,90112
63712 - Nicotinic receptor ligand binding domain-like
90112 - Neurotransmitter-gated ion-channel transmembrane pore | 0.3528 | Inherited |
54928,54928
54928 - RNA-binding domain, RBD
54928 - RNA-binding domain, RBD | 0.3708 | Inherited |
52833,47616
52833 - Thioredoxin-like
47616 - GST C-terminal domain-like | 0.4664 | Inherited |
48403,48403
48403 - Ankyrin repeat
48403 - Ankyrin repeat | 0.4686 | Inherited |
57716,57716
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0.4851 | Inherited |
50044,55550
50044 - SH3-domain
55550 - SH2 domain | 0.5662 | Inherited |
101690,53098
101690 - PAZ domain
53098 - Ribonuclease H-like | 0.5662 | Inherited |
51045,51045
51045 - WW domain
51045 - WW domain | 0.623 | Inherited |
63380,52343
63380 - Riboflavin synthase domain-like
52343 - Ferredoxin reductase-like, C-terminal NADP-linked domain | 0.623 | Inherited |
57424,57424
57424 - LDL receptor-like module
57424 - LDL receptor-like module | 0.661 | Inherited |
57903,57903
57903 - FYVE/PHD zinc finger
57903 - FYVE/PHD zinc finger | 0.6862 | Inherited |
50249,55681
50249 - Nucleic acid-binding proteins
55681 - Class II aaRS and biotin synthetases | 0.6862 | Inherited |
57716,48508
57716 - Glucocorticoid receptor-like (DNA-binding domain)
48508 - Nuclear receptor ligand-binding domain | 0.7214 | Inherited |
57196,57196
57196 - EGF/Laminin
57196 - EGF/Laminin | 0.7291 | Inherited |
51905,54373
51905 - FAD/NAD(P)-binding domain
54373 - FAD-linked reductases, C-terminal domain | 0.7403 | Inherited |
55550,50044
55550 - SH2 domain
50044 - SH3-domain | 0.7544 | Inherited |
48726,49265
48726 - Immunoglobulin
49265 - Fibronectin type III | 0.8362 | Inherited |
48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin | 0.8801 | Inherited |
54211,55666
54211 - Ribosomal protein S5 domain 2-like
55666 - Ribonuclease PH domain 2-like | 0.933 | Inherited |
49785,49785
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like | 0.9376 | Inherited |
49562,49562
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0.9409 | Inherited |
57850,57850
57850 - RING/U-box
57850 - RING/U-box | 1 | Inherited |
53300,56436
53300 - vWA-like
56436 - C-type lectin-like | 1 | Inherited |
52777,52777
52777 - CoA-dependent acyltransferases
52777 - CoA-dependent acyltransferases | 1 | Inherited |
57850,57845
57850 - RING/U-box
57845 - B-box zinc-binding domain | 1 | Inherited |
(show details)
Supra-domains annotated to this WP term (Not in SPWP)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
50044,50044,50044
50044 - SH3-domain
50044 - SH3-domain
50044 - SH3-domain | 0 | DIRECT |
57535,57535,57535
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | DIRECT |
52540,50447,50465
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
50249,50249,50249
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
48592,54849,52029
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0 | DIRECT |
82895,82895,82895
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat | 0 | DIRECT |
56968,48431,56968
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
48431 - Lipovitellin-phosvitin complex, superhelical domain
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | DIRECT |
49899,49899,49899
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
81301,81631,55003
81301 - Nucleotidyltransferase
81631 - PAP/OAS1 substrate-binding domain
55003 - PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | DIRECT |
47090,55486,50923
47090 - PGBD-like
55486 - Metalloproteases ("zincins"), catalytic domain
50923 - Hemopexin-like domain | 0 | DIRECT |
52440,56059,51246
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 0 | DIRECT |
54585,52540,52540
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
49562,48371,56112
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
52540,52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
74650,51445,51011
74650 - Galactose mutarotase-like
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain | 0 | DIRECT |
57625,57625,57625
57625 - Invertebrate chitin-binding proteins
57625 - Invertebrate chitin-binding proteins
57625 - Invertebrate chitin-binding proteins | 0 | DIRECT |
46938,52087,101576
46938 - CRAL/TRIO N-terminal domain
52087 - CRAL/TRIO domain
101576 - Supernatant protein factor (SPF), C-terminal domain | 0 | DIRECT |
54928,54928,54928
54928 - RNA-binding domain, RBD
54928 - RNA-binding domain, RBD
54928 - RNA-binding domain, RBD | 0 | DIRECT |
48726,49265,48726
48726 - Immunoglobulin
49265 - Fibronectin type III
48726 - Immunoglobulin | 0 | DIRECT |
53067,53067,100920
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
90123,52540,90123
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region | 0 | DIRECT |
56436,49854,49854
56436 - C-type lectin-like
49854 - Spermadhesin, CUB domain
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
54160,54160,52540
54160 - Chromo domain-like
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
46966,46966,46966
46966 - Spectrin repeat
46966 - Spectrin repeat
46966 - Spectrin repeat | 0 | DIRECT |
74788,75632,46785
74788 - Cullin repeat-like
75632 - Cullin homology domain
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
48452,48452,48452
48452 - TPR-like
48452 - TPR-like
48452 - TPR-like | 0 | DIRECT |
55973,55973,55973
55973 - S-adenosylmethionine synthetase
55973 - S-adenosylmethionine synthetase
55973 - S-adenosylmethionine synthetase | 0 | DIRECT |
57414,57414,57414
57414 - Hairpin loop containing domain-like
57414 - Hairpin loop containing domain-like
57414 - Hairpin loop containing domain-like | 0 | DIRECT |
50692,54585,52540
50692 - ADC-like
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
53738,53738,53738
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains | 0 | DIRECT |
54897,52743,49785
54897 - Protease propeptides/inhibitors
52743 - Subtilisin-like
49785 - Galactose-binding domain-like | 0 | DIRECT |
49313,49313,49313
49313 - Cadherin-like
49313 - Cadherin-like
49313 - Cadherin-like | 0 | DIRECT |
53738,53738,55957
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains
55957 - Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
57567,57567,57567
57567 - Serine protease inhibitors
57567 - Serine protease inhibitors
57567 - Serine protease inhibitors | 0 | DIRECT |
56112,82615,82615
56112 - Protein kinase-like (PK-like)
82615 - Polo-box domain
82615 - Polo-box domain | 0 | DIRECT |
54160,52540,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
81296,81296,81296
81296 - E set domains
81296 - E set domains
81296 - E set domains | 0 | DIRECT |
54292,47741,56176
54292 - 2Fe-2S ferredoxin-like
47741 - CO dehydrogenase ISP C-domain like
56176 - FAD-binding/transporter-associated domain-like | 0 | DIRECT |
54236,47031,50729
54236 - Ubiquitin-like
47031 - Second domain of FERM
50729 - PH domain-like | 0 | DIRECT |
53067,100920,100934
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
52540,90123,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
57362,57362,57362
57362 - BPTI-like
57362 - BPTI-like
57362 - BPTI-like | 0 | DIRECT |
57938,49493,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
50156,50044,52540
50156 - PDZ domain-like
50044 - SH3-domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
56645,47203,47203
56645 - Acyl-CoA dehydrogenase NM domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
50044,55550,56112
50044 - SH3-domain
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
50729,47473,51695
50729 - PH domain-like
47473 - EF-hand
51695 - PLC-like phosphodiesterases | 0 | DIRECT |
51735,48179,48179
51735 - NAD(P)-binding Rossmann-fold domains
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | DIRECT |
48371,48371,48371
48371 - ARM repeat
48371 - ARM repeat
48371 - ARM repeat | 0 | DIRECT |
81660,56784,81665
81660 - Metal cation-transporting ATPase, ATP-binding domain N
56784 - HAD-like
81665 - Calcium ATPase, transmembrane domain M | 0.1554 | INHERITED FROM: organism environmental stimulus response variant || drug hypersensitive || nicotine hypersensitive || lipid composition variant |
57424,57424,57424
57424 - LDL receptor-like module
57424 - LDL receptor-like module
57424 - LDL receptor-like module | 0.3866 | INHERITED FROM: protein expression reduced || level of protein expression variant |
52833,52833,52833
52833 - Thioredoxin-like
52833 - Thioredoxin-like
52833 - Thioredoxin-like | 0.3866 | INHERITED FROM: protein aggregation variant || pattern of transgene expression variant || protein protein interaction variant || protein interaction variant |
56436,56436,49854
56436 - C-type lectin-like
56436 - C-type lectin-like
49854 - Spermadhesin, CUB domain | 0.3962 | INHERITED FROM: cadmium response variant || cadmium hypersensitive |
57716,57716,57716
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0.4686 | INHERITED FROM: protein expression reduced || level of protein expression variant || protein degradation variant || organism metabolism processing variant || protein expression variant |
57850,57850,57850
57850 - RING/U-box
57850 - RING/U-box
57850 - RING/U-box | 0.8607 | INHERITED FROM: protein aggregation variant || transgene subcellular localization variant || pattern of transgene expression variant || protein protein interaction variant || protein interaction variant |
48726,48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin
48726 - Immunoglobulin | 0.9672 | INHERITED FROM: protein degradation variant || growth rate variant |
48726,48726,49265
48726 - Immunoglobulin
48726 - Immunoglobulin
49265 - Fibronectin type III | 1 | INHERITED FROM: protein degradation variant || growth rate variant |
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
50044,50044,50044
50044 - SH3-domain
50044 - SH3-domain
50044 - SH3-domain | 0 | Direct |
57535,57535,57535
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | Direct |
52540,50447,50465
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
50249,50249,50249
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins | 0 | Direct |
48592,54849,52029
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0 | Direct |
82895,82895,82895
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat | 0 | Direct |
56968,48431,56968
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
48431 - Lipovitellin-phosvitin complex, superhelical domain
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | Direct |
49899,49899,49899
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
81301,81631,55003
81301 - Nucleotidyltransferase
81631 - PAP/OAS1 substrate-binding domain
55003 - PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | Direct |
47090,55486,50923
47090 - PGBD-like
55486 - Metalloproteases ("zincins"), catalytic domain
50923 - Hemopexin-like domain | 0 | Direct |
52440,56059,51246
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 0 | Direct |
54585,52540,52540
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
49562,48371,56112
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat
56112 - Protein kinase-like (PK-like) | 0 | Direct |
52540,52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
74650,51445,51011
74650 - Galactose mutarotase-like
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain | 0 | Direct |
57625,57625,57625
57625 - Invertebrate chitin-binding proteins
57625 - Invertebrate chitin-binding proteins
57625 - Invertebrate chitin-binding proteins | 0 | Direct |
46938,52087,101576
46938 - CRAL/TRIO N-terminal domain
52087 - CRAL/TRIO domain
101576 - Supernatant protein factor (SPF), C-terminal domain | 0 | Direct |
54928,54928,54928
54928 - RNA-binding domain, RBD
54928 - RNA-binding domain, RBD
54928 - RNA-binding domain, RBD | 0 | Direct |
48726,49265,48726
48726 - Immunoglobulin
49265 - Fibronectin type III
48726 - Immunoglobulin | 0 | Direct |
53067,53067,100920
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
90123,52540,90123
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region | 0 | Direct |
56436,49854,49854
56436 - C-type lectin-like
49854 - Spermadhesin, CUB domain
49854 - Spermadhesin, CUB domain | 0 | Direct |
54160,54160,52540
54160 - Chromo domain-like
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
46966,46966,46966
46966 - Spectrin repeat
46966 - Spectrin repeat
46966 - Spectrin repeat | 0 | Direct |
74788,75632,46785
74788 - Cullin repeat-like
75632 - Cullin homology domain
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
48452,48452,48452
48452 - TPR-like
48452 - TPR-like
48452 - TPR-like | 0 | Direct |
55973,55973,55973
55973 - S-adenosylmethionine synthetase
55973 - S-adenosylmethionine synthetase
55973 - S-adenosylmethionine synthetase | 0 | Direct |
57414,57414,57414
57414 - Hairpin loop containing domain-like
57414 - Hairpin loop containing domain-like
57414 - Hairpin loop containing domain-like | 0 | Direct |
50692,54585,52540
50692 - ADC-like
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
53738,53738,53738
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains | 0 | Direct |
54897,52743,49785
54897 - Protease propeptides/inhibitors
52743 - Subtilisin-like
49785 - Galactose-binding domain-like | 0 | Direct |
49313,49313,49313
49313 - Cadherin-like
49313 - Cadherin-like
49313 - Cadherin-like | 0 | Direct |
53738,53738,55957
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains
55957 - Phosphoglucomutase, C-terminal domain | 0 | Direct |
57567,57567,57567
57567 - Serine protease inhibitors
57567 - Serine protease inhibitors
57567 - Serine protease inhibitors | 0 | Direct |
56112,82615,82615
56112 - Protein kinase-like (PK-like)
82615 - Polo-box domain
82615 - Polo-box domain | 0 | Direct |
54160,52540,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
81296,81296,81296
81296 - E set domains
81296 - E set domains
81296 - E set domains | 0 | Direct |
54292,47741,56176
54292 - 2Fe-2S ferredoxin-like
47741 - CO dehydrogenase ISP C-domain like
56176 - FAD-binding/transporter-associated domain-like | 0 | Direct |
54236,47031,50729
54236 - Ubiquitin-like
47031 - Second domain of FERM
50729 - PH domain-like | 0 | Direct |
53067,100920,100934
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
52540,90123,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
57362,57362,57362
57362 - BPTI-like
57362 - BPTI-like
57362 - BPTI-like | 0 | Direct |
57938,49493,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
50156,50044,52540
50156 - PDZ domain-like
50044 - SH3-domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
56645,47203,47203
56645 - Acyl-CoA dehydrogenase NM domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
50044,55550,56112
50044 - SH3-domain
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0 | Direct |
50729,47473,51695
50729 - PH domain-like
47473 - EF-hand
51695 - PLC-like phosphodiesterases | 0 | Direct |
51735,48179,48179
51735 - NAD(P)-binding Rossmann-fold domains
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | Direct |
48371,48371,48371
48371 - ARM repeat
48371 - ARM repeat
48371 - ARM repeat | 0 | Direct |
81660,56784,81665
81660 - Metal cation-transporting ATPase, ATP-binding domain N
56784 - HAD-like
81665 - Calcium ATPase, transmembrane domain M | 0.1554 | Inherited |
57424,57424,57424
57424 - LDL receptor-like module
57424 - LDL receptor-like module
57424 - LDL receptor-like module | 0.3866 | Inherited |
52833,52833,52833
52833 - Thioredoxin-like
52833 - Thioredoxin-like
52833 - Thioredoxin-like | 0.3866 | Inherited |
56436,56436,49854
56436 - C-type lectin-like
56436 - C-type lectin-like
49854 - Spermadhesin, CUB domain | 0.3962 | Inherited |
57716,57716,57716
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0.4686 | Inherited |
57850,57850,57850
57850 - RING/U-box
57850 - RING/U-box
57850 - RING/U-box | 0.8607 | Inherited |
48726,48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin
48726 - Immunoglobulin | 0.9672 | Inherited |
48726,48726,49265
48726 - Immunoglobulin
48726 - Immunoglobulin
49265 - Fibronectin type III | 1 | Inherited |
Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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Trees by TreeVector
A presence/absence matrix is generated using protein domains and supradomains
for all genomes in SUPERFAMILY. The RAxML
software is used to produce a single, large tree topology using
heuristic parsimony methods. Genome combinations, or specific clades, can be displayed as
if individual trees had been produced. However, this data is extracted from the single
large tree. This produces a higher quality topology than if the trees had been produced
on their own, and allows the trees to be displayed instantly.
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