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Worm Phenotype (WP): organism physiology variant
(show info)
Phenotype Ontology
Like Gene Ontology (GO), phenotypy ontology classifies and organizes gene-mutant/null phenotypic information from the very general at the top to more specific terms in the directed acyclic graph (DAG) by viewing an individual term as a node and its relations to parental terms (allowing for multiple parents) as directed edges. To navigate this hierarchy, we display all parental phenotypic terms to the current phenotypic term of interest ordered by their shortest distances to the current term. Also, only direct children phenotypic terms of the current phenotypic term are listed. Phenotype ontologies we have incorporated are as follows:
- Disease Ontology (DO) Ontology (DO) DO semantically integrates disease and medical vocabularies through extensive cross mapping of DO terms to MeSH, ICD, NCI thesaurus, SNOMED and OMIM.
- Human Phenotype (HP) Ontology (HP) HP captures phenotypic abnormalities that are described in OMIM, along with the corresponding disease-causing genes. It includes three complementary biological concepts: Mode_of_Inheritance (MI), ONset_and_clinical_course (ON), and Phenotypic_Abnormality (PA).
- Mouse Phenotype (MP) Ontology (MP) MP describes phenotypes of the mouse after a specific gene is genetically disrupted. Using it, Mouse Genome Informatics (MGI) provides high-coverate gene-level phenotypes for the mouse.
- Worm Phenotype (WP) Ontology (WP) WP classifies and organizes phenotype descriptions for C. elegans and other nematodes. Using it, WormBase provides primary resource for phenotype annotations for C. elegans.
- Yeast Phenotype (YP) Ontology (YP) Based on YP which is the major contributor to the Ascomycete phenotype ontology, Saccharomyces Genome Database (SGD) provides single mutant phenotypes for every gene in the yeast genome.
- Fly Phenotype (FP) Ontology (FP) FP refers to FlyBase controlled vocabulary. Specifically, a structured controlled vocabulary is used for the annotation of alleles (for their mutagen etc) in FlyBase.
- Fly Anatomy (FA) Ontology (FA) FA is a structured controlled vocabulary of the anatomy of Drosophila melanogaster, used for the description of phenotypes and where a gene is expressed.
- Zebrafish Anatomy (ZA) Ontology (ZA) ZA displays anatomical terms of the zebrafish using standard anatomical nomenclature, together with affected genes.
- Xenopus Anatomy (XA) Ontology (XA) XA represents the lineage of tissues and the timing of development for frogs (Xenopus laevis and Xenopus tropicalis). It is used to annotate Xenopus gene expression patterns and mutant and morphant phenotypes.
- Arabidopsis Plant Ontology (AP) Ontology (AP) As a major contributor to Plant Ontology which describes plant anatomical and morphological structures (AN) and growth and developmental stages (DE), the Arabidopsis Information Resource (TAIR) provides arabidopsis plant ontology annotations for the model higher plant Arabidopsis thaliana.
- Enzyme Commission (EC) Ontology (EC) Each enzyme is allocated a four-digit EC number, the first three digits of which define the reaction catalysed and the fourth of which is a unique identifier (serial number). Each enzyme is also assigned a systematic name that uniquely defines the reaction catalysed.
- DrugBank ATC (DB) Ontology (DB) In the Anatomical Therapeutic Chemical (ATC) classification system, drugs are classified in groups at five different levels according to the organ or system (1st level, anatomical main group) on which they act and their therapeutic (2nd level, therapeutic subgroup), pharmacological (3rd level, pharmacological subgroup) and chemical properties (4th level, chemical subgroup; 5th level, chemical substance). Only drugs in DrugBank are considered.
- UniProtKB KeyWords (KW) Ontology (KW) Keywords in UniProtKB are controlled vocabulary, providing a summary of the entry content and are used to index UniProtKB/Swiss-Prot entries based on 10 categories (the category "Technical term" being excluded here). Each keyword is attributed manually to UniProtKB/Swiss-Prot entries and automatically to UniProtKB/TrEMBL entries (according to specific annotation rules).
- UniProtKB UniPathway (UP) Ontology (UP) UP is a fully manually curated resource for the representation and annotation of metabolic pathways, being used as controlled vocabulary for pathway annotation in UniProtKB.
Structural Domain Phenotype Ontology and its Annotations
Structural Classification of Proteins (SCOP) classifies evolutionary-related domains into Superfamily level and Family level. Using the phenotype ontologies above, we have generated the domain-centric phenotype annotations, and further identified those phenotype terms which are the most informative to annotate SCOP domains. Promisingly, domain-centric phenotypic annotations can serve as an alternative starting point to explore genotype-phenotype relationships. We provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.
- Structural Domain Disease Ontology (DO) Ontology (SDDO) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DO.txt, and the corresponding ontology:SDDO.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Human Phenotype (HP) Ontology (SDHP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2HP.txt, and the corresponding ontology:SDHP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Mouse Phenotype (MP) Ontology (SDMP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2MP.txt, and the corresponding ontology:SDMP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Worm Phenotype (WP) Ontology (SDWP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2WP.txt, and the corresponding ontology:SDWP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Yeast Phenotype (YP) Ontology (SDYP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2YP.txt, and the corresponding ontology:SDYP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Fly Phenotype (FP) Ontology (SDFP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FP.txt, and the corresponding ontology:SDFP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Fly Anatomy (FA) Ontology (SDFA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FA.txt, and the corresponding ontology:SDFA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Zebrafish Anatomy (ZA) Ontology (SDZA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2ZA.txt, and the corresponding ontology:SDZA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Xenopus Anatomy (XA) Ontology (SDXA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2XA.txt, and the corresponding ontology:SDXA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Arabidopsis Plant Ontology (AP) Ontology (SDAP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2AP.txt, and the corresponding ontology:SDAP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Enzyme Commission (EC) Ontology (SDEC) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2EC.txt, and the corresponding ontology:SDEC.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain DrugBank ATC (DB) Ontology (SDDB) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DB.txt, and the corresponding ontology:SDDB.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain UniProtKB KeyWords (KW) Ontology (SDKW) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2KW.txt, and the corresponding ontology:SDKW.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain UniProtKB UniPathway (UP) Ontology (SDUP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2UP.txt, and the corresponding ontology:SDUP.txt) and mysql tables (Domain2PO.sql.gz).
Supra-domain Phenotype Ontology and its Annotations
Although domain-centric annotations hold great promise in describing phenotypic nature of independent domains, most domains themselves may not just work alone. In multi-domain proteins, they may be combined together to form distinct domain architectures. The recombination of the existing domains is considered as one of major driving forces for phenotypic diversificaation. As an extension, we have also generated supra-domain phenotype ontology and its annotations. Compared to domain-centric phenotype ontology and annotations (SCOP domains at the Superfamily level and Family level), this version focuses on supra-domains and individual SCOP domains ONLY at the Superfamily level. Besides, in terms of individual superfamilies, their annotations from the domain-centric version may be different from those from supra-domains version. Depending on your focus, the former should be used for the consideration of both the Superfamily level and Family level, otherwise the latter should be used if you are interested in domain combinations. Also, we provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.
- Supra-domain Domain Disease Ontology (DO) Ontology (SPDO) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DO.txt, and the corresponding ontology:SPDO.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Human Phenotype (HP) Ontology (SPHO) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2HP.txt, and the corresponding ontology:SPHO.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Mouse Phenotype (MP) Ontology (SPMP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2MP.txt, and the corresponding ontology:SPMP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Worm Phenotype (WP) Ontology (SPWP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2WP.txt, and the corresponding ontology:SPWP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Yeast Phenotype (YP) Ontology (SPYP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2YP.txt, and the corresponding ontology:SPYP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Fly Phenotype (FP) Ontology (SPFP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FP.txt, and the corresponding ontology:SPFP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Fly Anatomy (FA) Ontology (SPFA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FA.txt, and the corresponding ontology:SPFA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Zebrafish Anatomy (ZA) Ontology (SPZA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2ZA.txt, and the corresponding ontology:SPZA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Xenopus Anatomy (XA) Ontology (SPXA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2XA.txt, and the corresponding ontology:SPXA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Arabidopsis Plant Ontology (AP) Ontology (SPAP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2AP.txt, and the corresponding ontology:SPAP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Enzyme Commission (EC) Ontology (SPEC) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2EC.txt, and the corresponding ontology:SPEC.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain DrugBank ATC (DB) Ontology (SPDB) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DB.txt, and the corresponding ontology:SPDB.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain UniProtKB KeyWords (KW) Ontology (SPKW) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2KW.txt, and the corresponding ontology:SPKW.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain UniProtKB UniPathway (UP) Ontology (SPUP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2UP.txt, and the corresponding ontology:SPUP.txt) and mysql tables (SP2PO.sql.gz).
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Superfamily(show details)
Superfamily domains annotated to this WP term (Not in SDWP)
Highlighted in gray are those with FDR_all>0.001
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| LDH C-terminal domain-like | 0 | DIRECT |
| Thiolase-like | 0 | DIRECT |
| PurM C-terminal domain-like | 0 | DIRECT |
| Clathrin adaptor appendage domain | 0 | DIRECT |
| Aminoacid dehydrogenase-like, N-terminal domain | 0 | DIRECT |
| Restriction endonuclease-like | 0 | DIRECT |
| Blood coagulation inhibitor (disintegrin) | 0 | DIRECT |
| Thyroglobulin type-1 domain | 0 | DIRECT |
| PEP carboxykinase-like | 0 | DIRECT |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | DIRECT |
| Hedgehog/intein (Hint) domain | 0 | DIRECT |
| Ribokinase-like | 0 | DIRECT |
| Carbon-nitrogen hydrolase | 0 | DIRECT |
| DNA ligase/mRNA capping enzyme, catalytic domain | 0 | DIRECT |
| Intermediate filament protein, coiled coil region | 0 | DIRECT |
| Ribosomal proteins S24e, L23 and L15e | 0 | DIRECT |
| Carbonic anhydrase | 0 | DIRECT |
| Ferritin-like | 0 | DIRECT |
| Class I glutamine amidotransferase-like | 0 | DIRECT |
| TK C-terminal domain-like | 0 | DIRECT |
| Periplasmic binding protein-like II | 0 | DIRECT |
| eIF4e-like | 0 | DIRECT |
| PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | DIRECT |
| GINS helical bundle-like | 0 | DIRECT |
| SMAD/FHA domain | 0 | DIRECT |
| CO dehydrogenase molybdoprotein N-domain-like | 0 | DIRECT |
| Bacterial exopeptidase dimerisation domain | 0 | DIRECT |
| Aquaporin-like | 0 | DIRECT |
| GroEL-intermediate domain like | 0 | DIRECT |
| Chromo domain-like | 0 | DIRECT |
| PIN domain-like | 0 | DIRECT |
| ADP-ribosylation | 0 | DIRECT |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | DIRECT |
| Tubulin nucleotide-binding domain-like | 0 | DIRECT |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| F1F0 ATP synthase subunit C | 0 | DIRECT |
| Doublecortin (DC) | 0 | DIRECT |
| Ribosomal protein L1 | 0 | DIRECT |
| PYP-like sensor domain (PAS domain) | 0 | DIRECT |
| Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | DIRECT |
| PK beta-barrel domain-like | 0 | DIRECT |
| ISP domain | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
| alpha/beta knot | 0 | DIRECT |
| Cdc48 domain 2-like | 0 | DIRECT |
| LysM domain | 0 | DIRECT |
| 3-carboxy-cis,cis-mucoante lactonizing enzyme | 0 | DIRECT |
| PAP/OAS1 substrate-binding domain | 0 | DIRECT |
| Rudiment single hybrid motif | 0 | DIRECT |
| Pepsin inhibitor-3 | 0 | DIRECT |
| Glutathione synthetase ATP-binding domain-like | 0 | DIRECT |
| 2Fe-2S ferredoxin-like | 0 | DIRECT |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0 | DIRECT |
| PurM N-terminal domain-like | 0 | DIRECT |
| CRAL/TRIO N-terminal domain | 0 | DIRECT |
| BEACH domain | 0 | DIRECT |
| HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
| PHM/PNGase F | 0 | DIRECT |
| Subtilisin-like | 0 | DIRECT |
| Calcium-dependent phosphotriesterase | 0 | DIRECT |
| GYF domain | 0 | DIRECT |
| YWTD domain | 0 | DIRECT |
| ENTH/VHS domain | 0 | DIRECT |
| MFPT repeat-like | 0 | DIRECT |
| MIR domain | 0 | DIRECT |
| Subdomain of clathrin and coatomer appendage domain | 0 | DIRECT |
| TGS-like | 0 | DIRECT |
| Cullin homology domain | 0 | DIRECT |
| beta-lactamase/transpeptidase-like | 0 | DIRECT |
| Formate/glycerate dehydrogenase catalytic domain-like | 0 | DIRECT |
| Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | DIRECT |
| Integrin alpha N-terminal domain | 0 | DIRECT |
| Outer arm dynein light chain 1 | 0 | DIRECT |
| Integrin domains | 0 | DIRECT |
| FF domain | 0 | DIRECT |
| Domain of poly(ADP-ribose) polymerase | 0 | DIRECT |
| SMAD MH1 domain | 0 | DIRECT |
| Zn-finger domain of Sec23/24 | 0 | DIRECT |
| SAND domain-like | 0 | DIRECT |
| Actin-like ATPase domain | 0 | DIRECT |
| Activating enzymes of the ubiquitin-like proteins | 0 | DIRECT |
| L-aspartase-like | 0 | DIRECT |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
| LEM domain | 0 | DIRECT |
| Cystatin/monellin | 0 | DIRECT |
| Nucleotidyltransferase | 0 | DIRECT |
| Hormone receptor domain | 0 | DIRECT |
| Annexin | 0 | DIRECT |
| SAICAR synthase-like | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
| t-snare proteins | 0 | DIRECT |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
| GHMP Kinase, C-terminal domain | 0 | DIRECT |
| Phosphoenolpyruvate/pyruvate domain | 0 | DIRECT |
| PreATP-grasp domain | 0 | DIRECT |
| Transducin (heterotrimeric G protein), gamma chain | 0 | DIRECT |
| Thiamin diphosphate-binding fold (THDP-binding) | 0 | DIRECT |
| Terpenoid cyclases/Protein prenyltransferases | 0 | DIRECT |
| Isocitrate/Isopropylmalate dehydrogenase-like | 0 | DIRECT |
| JAB1/MPN domain | 0 | DIRECT |
| PEP carboxykinase N-terminal domain | 0 | DIRECT |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
| PP2C-like | 0 | DIRECT |
| Fibrinogen C-terminal domain-like | 0 | DIRECT |
| WWE domain | 0 | DIRECT |
| Carbohydrate phosphatase | 0 | DIRECT |
| Citrate synthase | 0 | DIRECT |
| Tricorn protease domain 2 | 0 | DIRECT |
| L30e-like | 0 | DIRECT |
| Polo-box domain | 0 | DIRECT |
| Ran binding protein zinc finger-like | 0 | DIRECT |
| Creatinase/prolidase N-terminal domain | 0 | DIRECT |
| Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0 | DIRECT |
| Glycolipid transfer protein, GLTP | 0 | DIRECT |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
| Tubby C-terminal domain-like | 0 | DIRECT |
| Oxysterol-binding protein-like | 0 | DIRECT |
| cAMP-binding domain-like | 0 | DIRECT |
| Cadherin-like | 0 | DIRECT |
| Invertebrate chitin-binding proteins | 0 | DIRECT |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | DIRECT |
| HSP90 C-terminal domain | 0 | DIRECT |
| GAS2 domain-like | 0 | DIRECT |
| Molybdenum cofactor-binding domain | 0 | DIRECT |
| Troponin coil-coiled subunits | 0 | DIRECT |
| DNA repair protein MutS, domain III | 0 | DIRECT |
| Elafin-like | 0 | DIRECT |
| SCP-like | 0 | DIRECT |
| Galactose mutarotase-like | 0 | DIRECT |
| alpha-catenin/vinculin-like | 0 | DIRECT |
| Sec7 domain | 0 | DIRECT |
| Single hybrid motif | 0 | DIRECT |
| MgtE membrane domain-like | 0 | DIRECT |
| Heme-dependent catalase-like | 0 | DIRECT |
| YbiA-like | 0 | DIRECT |
| Class II aaRS ABD-related | 0 | DIRECT |
| Band 7/SPFH domain | 0 | DIRECT |
| dsRNA-binding domain-like | 0 | DIRECT |
| Nucleoside diphosphate kinase, NDK | 0 | DIRECT |
| Profilin (actin-binding protein) | 0 | DIRECT |
| Purine and uridine phosphorylases | 0 | DIRECT |
| FAD-dependent thiol oxidase | 0 | DIRECT |
| HMG-box | 0 | DIRECT |
| Alpha-L RNA-binding motif | 0 | DIRECT |
| CBD9-like | 0 | DIRECT |
| S-adenosylmethionine synthetase | 0 | DIRECT |
| Spectrin repeat | 0 | DIRECT |
| HCP-like | 0 | DIRECT |
| MOSC N-terminal domain-like | 0 | DIRECT |
| Sec1/munc18-like (SM) proteins | 0 | DIRECT |
| Cation efflux protein cytoplasmic domain-like | 0 | DIRECT |
| Ribosomal L27 protein-like | 0 | DIRECT |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | DIRECT |
| Radical SAM enzymes | 0 | DIRECT |
| Families 57/38 glycoside transferase middle domain | 0 | DIRECT |
| Proton glutamate symport protein | 0 | DIRECT |
| Skp1 dimerisation domain-like | 0 | DIRECT |
| FtsH protease domain-like | 0 | DIRECT |
| Type II DNA topoisomerase | 0 | DIRECT |
| Second domain of FERM | 0 | DIRECT |
| Acid phosphatase/Vanadium-dependent haloperoxidase | 0 | DIRECT |
| Cytochrome c | 0 | DIRECT |
| Rap/Ran-GAP | 0 | DIRECT |
| VPS9 domain | 0 | DIRECT |
| Tubulin C-terminal domain-like | 0 | DIRECT |
| Cu,Zn superoxide dismutase-like | 0 | DIRECT |
| Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | DIRECT |
| ThrRS/AlaRS common domain | 0 | DIRECT |
| Arginase/deacetylase | 0 | DIRECT |
| SPOC domain-like | 0 | DIRECT |
| Insulin-like | 0 | DIRECT |
| SIS domain | 0 | DIRECT |
| GroES-like | 0 | DIRECT |
| lambda repressor-like DNA-binding domains | 0 | DIRECT |
| Sec63 N-terminal domain-like | 0 | DIRECT |
| Nop domain | 0 | DIRECT |
| Transducin (alpha subunit), insertion domain | 0 | DIRECT |
| PUA domain-like | 0 | DIRECT |
| DEATH domain | 0 | DIRECT |
| Putative DNA-binding domain | 0 | DIRECT |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | DIRECT |
| Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
| Heme-dependent peroxidases | 0 | DIRECT |
| PLC-like phosphodiesterases | 0 | DIRECT |
| Lamin A/C globular tail domain | 0 | DIRECT |
| Acyl-CoA dehydrogenase NM domain-like | 0 | DIRECT |
| Clc chloride channel | 0 | DIRECT |
| ValRS/IleRS/LeuRS editing domain | 0 | DIRECT |
| Ribulose-phoshate binding barrel | 0 | DIRECT |
| Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
| RBP11-like subunits of RNA polymerase | 0 | DIRECT |
| Nucleoporin domain | 0 | DIRECT |
| WGR domain-like | 0 | DIRECT |
| Kringle-like | 0 | DIRECT |
| ARID-like | 0 | DIRECT |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
| ClpP/crotonase | 0 | DIRECT |
| AN1-like Zinc finger | 0 | DIRECT |
| Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | DIRECT |
| Zn-binding ribosomal proteins | 0 | DIRECT |
| Complement control module/SCR domain | 0 | DIRECT |
| Phosphoglucomutase, first 3 domains | 0 | DIRECT |
| Protease propeptides/inhibitors | 0 | DIRECT |
| Ribosomal protein L10-like | 0 | DIRECT |
| GAT-like domain | 0 | DIRECT |
| ArfGap/RecO-like zinc finger | 0 | DIRECT |
| Diaminopimelate epimerase-like | 0 | DIRECT |
| Translational machinery components | 0 | DIRECT |
| ALDH-like | 0 | DIRECT |
| Aldolase | 0 | DIRECT |
| Hect, E3 ligase catalytic domain | 0 | DIRECT |
| Carboxypeptidase regulatory domain-like | 0 | DIRECT |
| Mitochondrial carrier | 0 | DIRECT |
| R3H domain | 0 | DIRECT |
| 14-3-3 protein | 0 | DIRECT |
| HSP20-like chaperones | 0 | DIRECT |
| GroEL apical domain-like | 0 | DIRECT |
| CAD & PB1 domains | 0 | DIRECT |
| Surp module (SWAP domain) | 0 | DIRECT |
| PEBP-like | 0 | DIRECT |
| Galactose oxidase, central domain | 0 | DIRECT |
| Smc hinge domain | 0 | DIRECT |
| Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
| Succinyl-CoA synthetase domains | 0 | DIRECT |
| Pentein | 0 | DIRECT |
| Helical domain of Sec23/24 | 0 | DIRECT |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Terpenoid synthases | 0 | DIRECT |
| Chitinase insertion domain | 0 | DIRECT |
| GroEL equatorial domain-like | 0 | DIRECT |
| SWIB/MDM2 domain | 0 | DIRECT |
| Small-conductance potassium channel | 0 | DIRECT |
| DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
| CO dehydrogenase ISP C-domain like | 0 | DIRECT |
| Hypothetical protein c14orf129, hspc210 | 0 | DIRECT |
| Chaperone J-domain | 0 | DIRECT |
| PABC (PABP) domain | 0 | DIRECT |
| PGBD-like | 0 | DIRECT |
| Tim10-like | 0 | DIRECT |
| Cullin repeat-like | 0 | DIRECT |
| PLP-binding barrel | 0 | DIRECT |
| P-loop containing nucleoside triphosphate hydrolases | 0.0000002719 | DIRECT |
| PH domain-like | 0.00009596 | DIRECT |
| Histone-fold | 0.0001964 | DIRECT |
| Protein kinase-like (PK-like) | 0.009874 | INHERITED FROM: second messenger mediated signaling variant || protein phosphorylation variant || kinase activity reduced || organism osmostic stress hypersensitive || conflicting sensory integration variant || pathogen induced gene expression variant || aldicarb response variant || metal response variant || life span variant || protein expression variant || organism environmental stimulus response variant || positive chemotaxis variant || transgene expression reduced || egg laying response to food variant || alkaline pH chemotaxis variant || protein phosphorylation reduced || chemical response variant || protein subcellular localization variant || colchicine resistant || drug induced gene expression variant || lipid synthesis increased || anoxia resistant |
| PDZ domain-like | 0.01497 | INHERITED FROM: drug resistant || acetylcholinesterase inhibitor response variant || aldicarb response variant |
| Nucleic acid-binding proteins | 0.02331 | INHERITED FROM: sick || hypoxia resistant || hydroxyurea hypersensitive || hydroxyurea response variant || mRNA surveillance defective || nonsense mRNA accumulation |
| Periplasmic binding protein-like I | 0.02384 | INHERITED FROM: lithium chemotaxis defective || second messenger mediated signaling variant || chemotaxis variant || magnesium chemotaxis defective || AWC odorant chemotaxis defective || AWC odorant chemotaxis variant || organism environmental stimulus response variant || benzaldehyde chemotaxis variant || iodide chemotaxis variant || alkaline pH chemotaxis variant || bromide chemotaxis defective || response to food variant || diacetyl chemotaxis variant || bromide chemotaxis variant || chemical response variant || aqueous chemosensory response variant || aqueous positive chemotaxis variant || memory retention defective || chemosensory response variant || iodide chemotaxis defective || carbon dioxide avoidance variant |
| TPR-like | 0.0263 | INHERITED FROM: light body touch resistant || chemotaxis variant || associative learning variant || dauer defective || positive chemotaxis defective |
| "Winged helix" DNA-binding domain | 0.03247 | INHERITED FROM: protein expression increased || chemical hypersensitive || paraquat hypersensitive || anesthetic response variant || life span variant || protein aggregation induced behavior variant || spontaneous mutation rate increased || organism metabolism processing variant || germline transgene silencing variant || protein protein interaction variant || protein aggregation variant || growth rate variant |
| PapD-like | 0.03972 | INHERITED FROM: dauer metabolism variant || dauer lifespan extended || developmental growth variant || larval arrest || dauer lifespan variant || lipid metabolism variant || fat content variant || slow growth || larval growth variant |
| WD40 repeat-like | 0.05101 | INHERITED FROM: late larval arrest || antimicrobial gene expression variant || early larval arrest || osmotic avoidance variant || protein aggregation induced behavior variant || organism metabolism processing variant || protein protein interaction variant || protein aggregation variant |
| ARM repeat | 0.05182 | INHERITED FROM: sick || gene expression variant || protein expression variant || RNAi response variant || organism metabolism processing variant || organism hypersensitive ionizing radiation |
| SH2 domain | 0.05673 | INHERITED FROM: protein expression variant || level of protein expression variant || protein expression reduced || aldicarb resistant || acetylcholinesterase inhibitor resistant |
| Homeodomain-like | 0.07731 | INHERITED FROM: protein degradation variant || carbon dioxide response variant || ectopic expression transgene || level of transgene expression variant || imipramine resistant || organism metabolism processing variant || inhibitor of serotonin uptake variant || sexually dimorphic physiology variant || egg laying imipramine resistant || adrenergic receptor antagonist response variant || carbon dioxide avoidance variant || growth rate variant |
| Acetyl-CoA synthetase-like | 0.07972 | INHERITED FROM: lipid metabolism variant |
| Calponin-homology domain, CH-domain | 0.07972 | INHERITED FROM: protein degradation variant |
| Cyclin-like | 0.088 | INHERITED FROM: protein phosphorylation variant || protein phosphorylation reduced |
| CCCH zinc finger | 0.09702 | INHERITED FROM: transgene expression variant || gene expression variant || ectopic expression transgene || mRNA expression ectopic |
| EGF/Laminin | 0.1062 | INHERITED FROM: odorant negative chemotaxis defective || octanol chemotaxis defective || octanol chemotaxis variant || negative chemotaxis variant |
| Translation proteins | 0.1182 | INHERITED FROM: proteasome core activity variant || sick || protein phosphorylation variant || transgene expression variant || gene expression variant || protein phosphorylation increased || mRNA levels increased || organism metabolism processing variant || protein protein interaction variant || protein aggregation variant |
| Galactose-binding domain-like | 0.126 | INHERITED FROM: protein interaction variant || protein protein interaction variant || protein aggregation variant |
| Ankyrin repeat | 0.13 | INHERITED FROM: chemotaxis variant || organism heat response variant || odorant negative chemotaxis defective || octanol chemotaxis defective || octanol chemotaxis variant || chemosensory response variant |
| HLH, helix-loop-helix DNA-binding domain | 0.1473 | INHERITED FROM: hypoxia response variant || ectopic expression transgene || aqueous positive chemotaxis defective || lysine chemotaxis defective || organism metabolism processing variant || gene expression level reduced || RNA expression variant |
| Nucleotide cyclase | 0.1473 | INHERITED FROM: lithium chemotaxis defective || second messenger mediated signaling variant || anion positive chemotaxis defective || carbon dioxide response variant || chemotaxis variant || magnesium chemotaxis defective || AWC odorant chemotaxis defective || cation positive chemotaxis defective || AWC odorant chemotaxis variant || organism environmental stimulus response variant || osmotic avoidance variant || positive chemotaxis variant || iodide chemotaxis variant || alkaline pH chemotaxis variant || bromide chemotaxis defective || diacetyl chemotaxis variant || bromide chemotaxis variant || chemosensory response variant || iodide chemotaxis defective |
| ABC transporter transmembrane region | 0.1473 | INHERITED FROM: metal response variant || organism environmental stimulus response variant || colchicine hypersensitive || RNAi response variant || cadmium response variant |
| RNI-like | 0.1553 | INHERITED FROM: resistant to protein aggregation induced paralysis |
| Calcium ATPase, transmembrane domain M | 0.1577 | INHERITED FROM: lipid composition variant || organism environmental stimulus response variant || nicotine hypersensitive |
| Metal cation-transporting ATPase, ATP-binding domain N | 0.174 | INHERITED FROM: lipid composition variant || organism environmental stimulus response variant || nicotine hypersensitive |
| Regulator of G-protein signaling, RGS | 0.174 | INHERITED FROM: chemotaxis variant || mechanosensation variant || negative chemotaxis variant |
| Calcium ATPase, transduction domain A | 0.1913 | INHERITED FROM: organism environmental stimulus response variant || nicotine hypersensitive |
| Class II aaRS and biotin synthetases | 0.1913 | INHERITED FROM: oxygen response variant || transgene expression variant || hypoxia resistant || gene expression variant || hypoxia response variant || organism environmental stimulus response variant || organism metabolism processing variant |
| SH3-domain | 0.1972 | INHERITED FROM: protein phosphorylation variant || aldicarb response variant || protein expression variant || protein expression reduced |
| E set domains | 0.2001 | INHERITED FROM: paraquat hypersensitive |
| Quinoprotein alcohol dehydrogenase-like | 0.2104 | INHERITED FROM: protein degradation variant || hypoxia response variant || mid larval arrest || fat content increased || mRNA levels increased || L2 arrest |
| DBL homology domain (DH-domain) | 0.2314 | INHERITED FROM: protein degradation variant || bacterially unswollen || aldicarb response variant || organism pathogen response variant || organism environmental stimulus response variant || pathogen resistance increased |
| Multidrug efflux transporter AcrB transmembrane domain | 0.2325 | INHERITED FROM: egg integrity defective early emb || chemotaxis variant || embryo osmotic integrity defective early emb || odorant chemosensory response variant || odorant positive chemotaxis defective || positive chemotaxis defective |
| (Trans)glycosidases | 0.277 | INHERITED FROM: pathogen susceptibility increased || pathogen load variant |
| Cytochrome P450 | 0.277 | INHERITED FROM: metal response variant || cadmium response variant |
| Multidrug resistance efflux transporter EmrE | 0.2789 | INHERITED FROM: bacterially unswollen || pathogen resistance increased |
| BRCT domain | 0.2882 | INHERITED FROM: organism ionizing radiation response variant |
| 6-phosphogluconate dehydrogenase C-terminal domain-like | 0.3063 | INHERITED FROM: lipid metabolism variant || fat content variant |
| Bromodomain | 0.3063 | INHERITED FROM: organism UV hypersensitive || sick || anesthetic response variant || organism UV response variant || acute functional tolerance to alcohol defective || drug adaptation variant || ethanol resistant || anesthetic resistant |
| Nucleotidylyl transferase | 0.3309 | INHERITED FROM: oxygen response variant || hypoxia resistant || hypoxia response variant || transgene expression increased || organism environmental stimulus response variant || organism metabolism processing variant || paraquat resistant |
| POZ domain | 0.3327 | INHERITED FROM: chemical hypersensitive || L1 arrest || early larval arrest || protein aggregation induced behavior variant || resistant to protein aggregation induced paralysis |
| SNARE-like | 0.335 | INHERITED FROM: sick || transgene expression variant || pattern of transgene expression variant || gene expression variant || transgene subcellular localization variant || protein metabolism variant || organism metabolism processing variant || aldicarb resistant || acetylcholinesterase inhibitor resistant |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0.3403 | INHERITED FROM: aging variant || drug resistant || antimicrobial gene expression variant || nose touch variant || protein expression variant || organism environmental stimulus response variant || RNAi response variant || metabolic pathway variant || chemical response variant || protein subcellular localization variant || drug induced gene expression variant || growth rate variant |
| Cysteine proteinases | 0.3417 | INHERITED FROM: pattern of transgene expression variant || osmotic integrity variant || protein interaction variant || paraquat hypersensitive || organism metabolism processing variant || hypoosmotic shock hypersensitive || protein protein interaction variant |
| RNA-binding domain, RBD | 0.3451 | INHERITED FROM: sick || antimicrobial gene expression variant || alternative splicing variant || mRNA export variant || organism metabolism processing variant || no induction of antimicrobial peptide expression after infection || maintenance of gene silencing variant || innate immune response variant || RNA expression variant || RNA processing variant || starvation induced apoptosis variant |
| Ribosomal protein S5 domain 2-like | 0.3504 | INHERITED FROM: transgene expression variant || early larval arrest |
| SAM/Pointed domain | 0.3542 | INHERITED FROM: aldicarb response variant |
| Lipocalins | 0.3542 | INHERITED FROM: lipid metabolism variant || paraquat hypersensitive || fat content variant || fat content increased |
| Growth factor receptor domain | 0.3788 | INHERITED FROM: protein degradation variant |
| Translation proteins SH3-like domain | 0.4029 | INHERITED FROM: transgene expression variant || gene expression variant || early larval arrest || organism metabolism processing variant |
| Cation efflux protein transmembrane domain-like | 0.4029 | INHERITED FROM: metal response variant || cadmium hypersensitive || manganese response variant || manganese toxicity resistant |
| Acid proteases | 0.4327 | INHERITED FROM: transgene expression variant || pattern of transgene expression variant || osmotic integrity variant || gene expression variant || transgene subcellular localization variant || protein interaction variant || organism metabolism processing variant || hypoosmotic shock hypersensitive || protein protein interaction variant || protein aggregation variant |
| Nicotinic receptor ligand binding domain-like | 0.4544 | INHERITED FROM: cholinergic agonist resistant || mechanosensation variant || selenium response variant || organism environmental stimulus response variant || nicotine resistant || drug response variant || hypoosmotic shock hypersensitive || DMPP response variant || chemical response variant || aqueous chemosensory response variant || sodium chloride chemotaxis variant || antihelmintic response variant |
| Ubiquitin-like | 0.4649 | INHERITED FROM: protein interaction variant || heteroplasmy || organism metabolism processing variant || protein protein interaction variant || protein aggregation variant |
| FYVE/PHD zinc finger | 0.4661 | INHERITED FROM: organism UV hypersensitive || organism UV response variant || ectopic expression transgene || protein modification variant || protein methylation variant |
| Cysteine-rich domain | 0.4838 | INHERITED FROM: organism oxidative stress resistant || bacterially unswollen || antimicrobial gene expression variant || odorant positive chemotaxis variant || aldicarb response variant || organism pathogen response variant || odorant chemosensory response variant || positive chemotaxis variant || organism metabolism processing variant || protein subcellular localization variant || drug induced gene expression variant |
| HAD-like | 0.4852 | INHERITED FROM: nicotine hypersensitive |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.4908 | INHERITED FROM: cholinergic agonist resistant || protein degradation variant || mechanosensation variant || selenium response variant || organism environmental stimulus response variant || nicotine resistant || positive chemotaxis variant || drug response variant || hypoosmotic shock hypersensitive || DMPP response variant || chemical response variant || aqueous chemosensory response variant || sodium chloride chemotaxis variant || antihelmintic response variant |
| Myosin rod fragments | 0.5252 | INHERITED FROM: drug resistant |
| DHS-like NAD/FAD-binding domain | 0.5252 | INHERITED FROM: life span variant || protein modification variant || protein acetylation variant |
| PRTase-like | 0.5252 | INHERITED FROM: drug resistant || Fluorouracil resistant |
| Calpain large subunit, middle domain (domain III) | 0.573 | INHERITED FROM: protein degradation variant || protein metabolism variant || metabolic pathway variant |
| Ferredoxin reductase-like, C-terminal NADP-linked domain | 0.573 | INHERITED FROM: pattern protein expression variant |
| Riboflavin synthase domain-like | 0.573 | INHERITED FROM: pattern protein expression variant |
| WW domain | 0.5851 | INHERITED FROM: maintenance of gene silencing variant |
| Cystine-knot cytokines | 0.5851 | INHERITED FROM: nicotine response variant || levamisole response variant |
| Sm-like ribonucleoproteins | 0.5851 | INHERITED FROM: sick || transgene expression variant || pattern of transgene expression variant || gene expression variant || unfolded protein response variant || organism heat response variant || life span variant || protein subcellular localization variant |
| FAD-linked reductases, C-terminal domain | 0.5851 | INHERITED FROM: life span variant |
| GTPase activation domain, GAP | 0.5873 | INHERITED FROM: protein expression variant |
| Voltage-gated potassium channels | 0.619 | INHERITED FROM: protein degradation variant || serotonin response variant || mechanosensation variant || protein metabolism variant || metabolic pathway variant || adrenergic receptor antagonist response variant || positive chemotaxis defective || growth rate variant |
| Seven-hairpin glycosidases | 0.6221 | INHERITED FROM: extended life span || protein protein interaction variant || protein aggregation variant |
| FAD/NAD(P)-binding domain | 0.624 | INHERITED FROM: ATP levels reduced || life span variant || pesticide response variant || ATP levels variant |
| SET domain | 0.6304 | INHERITED FROM: histone methylation variant || somatic transgene silencing variant || life span variant || protein expression variant || protein modification variant || ectopic expression antibody || RNAi response variant || spontaneous mutation rate increased || shortened life span || protein methylation variant || maintenance of gene silencing variant || dosage compensation variant |
| UBC-like | 0.6542 | INHERITED FROM: sick || pattern of transgene expression variant || gene expression variant || transgene subcellular localization variant || protein interaction variant || late larval arrest || organism metabolism processing variant || protein protein interaction variant || protein aggregation variant |
| Lipovitellin-phosvitin complex, superhelical domain | 0.6786 | INHERITED FROM: organism pathogen response variant || life span variant || organism environmental stimulus response variant || pathogen susceptibility increased |
| Nucleotide-binding domain | 0.6786 | INHERITED FROM: extended life span || life span variant |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0.6786 | INHERITED FROM: organism pathogen response variant || life span variant || organism environmental stimulus response variant || pathogen susceptibility increased |
| KA1-like | 0.6786 | INHERITED FROM: RNA expression variant |
| Osmotin, thaumatin-like protein | 0.6786 | INHERITED FROM: metal response variant || cadmium hypersensitive || cadmium response variant |
| MFS general substrate transporter | 0.6868 | INHERITED FROM: organism high sodium chloride hypersensitive |
| Clavaminate synthase-like | 0.7247 | INHERITED FROM: life span variant || organism temperature response variant |
| S15/NS1 RNA-binding domain | 0.7382 | INHERITED FROM: transgene expression increased |
| Frizzled cysteine-rich domain | 0.7382 | INHERITED FROM: antibody staining variant || transgene expression reduced |
| 4Fe-4S ferredoxins | 0.7382 | INHERITED FROM: extended life span |
| GST C-terminal domain-like | 0.7652 | INHERITED FROM: enzyme activity reduced || enzyme activity variant || organism electrophilic stress hypersensitive || organism stress response variant || cadmium hypersensitive || organism heat hypersensitive || organism environmental stimulus response variant || cadmium response variant |
| PAZ domain | 0.7984 | INHERITED FROM: 21U RNA expression variant || somatic transgene silencing variant || RNAi enhanced || mRNA levels increased || RNAi response variant || siRNA expression variant || maintenance of gene silencing variant || RNA expression variant |
| Ribonuclease H-like | 0.8027 | INHERITED FROM: 21U RNA expression variant || somatic transgene silencing variant || RNAi enhanced || RNAi response variant || siRNA expression variant || maintenance of gene silencing variant || RNA expression variant |
| MIT domain | 0.8032 | INHERITED FROM: protein interaction variant || protein protein interaction variant || protein aggregation variant |
| Glucocorticoid receptor-like (DNA-binding domain) | 0.8032 | INHERITED FROM: dauer resistance to harsh conditions variant || gene expression level high || SDS sensitive dauer || fat content increased || transgene expression reduced || level of transgene expression variant || gene expression level reduced |
| ADC-like | 0.8032 | INHERITED FROM: protein interaction variant || protein metabolism variant || level of transgene expression variant || metabolic pathway variant || protein protein interaction variant || protein aggregation variant |
| alpha/beta-Hydrolases | 0.813 | INHERITED FROM: acetylcholinesterase activity variant || acetylcholinesterase reduced |
| Fibronectin type III | 0.8604 | INHERITED FROM: protein degradation variant |
| Leucine zipper domain | 0.9001 | INHERITED FROM: pore forming toxin response variant || mRNA levels reduced || mRNA expression variant || transgene expression reduced || level of transgene expression variant || pathogen susceptibility increased |
| UBA-like | 0.9108 | INHERITED FROM: protein protein interaction variant || protein aggregation variant |
| EF-hand | 0.9227 | INHERITED FROM: protein interaction variant || protein aggregation variant |
| beta-beta-alpha zinc fingers | 0.9494 | INHERITED FROM: imipramine resistant || egg laying serotonin resistant || organism metabolism processing variant || inhibitor of serotonin uptake variant || egg laying imipramine resistant |
| DNA/RNA polymerases | 0.9647 | INHERITED FROM: DNA metabolism variant || DNA repair variant |
| p53-like transcription factors | 0.9736 | INHERITED FROM: ectopic expression transgene || level of transgene expression variant || gene expression level reduced |
| Ribonuclease PH domain 2-like | 0.9749 | INHERITED FROM: early larval arrest |
| Immunoglobulin | 0.9992 | INHERITED FROM: protein degradation variant || aldicarb response variant || growth rate variant |
| CoA-dependent acyltransferases | 1 | INHERITED FROM: fat content variant |
| Cyclophilin-like | 1 | INHERITED FROM: transgene expression variant || pattern of transgene expression variant || gene expression variant || transgene subcellular localization variant || protein interaction variant || protein protein interaction variant || protein aggregation variant |
| Family A G protein-coupled receptor-like | 1 | INHERITED FROM: locomotion rate serotonin variant || serotonin induced pumping variant || male tail curling serotonin variant || serotonin induced fat reduction variant |
| B-box zinc-binding domain | 1 | INHERITED FROM: transgene expression variant || gene expression variant || transgene subcellular localization variant || protein interaction variant || organism metabolism processing variant || protein protein interaction variant || protein aggregation variant |
| Eukaryotic type KH-domain (KH-domain type I) | 1 | INHERITED FROM: RNA expression variant |
| FKBP-like | 1 | INHERITED FROM: pattern of transgene expression variant || transgene subcellular localization variant || protein interaction variant || protein protein interaction variant || protein aggregation variant |
| F-box domain | 1 | INHERITED FROM: resistant to protein aggregation induced paralysis |
| Ligand-binding domain in the NO signalling and Golgi transport | 1 | INHERITED FROM: carbon dioxide response variant || carbon dioxide avoidance variant |
| RING/U-box | 1 | INHERITED FROM: transgene expression variant || pattern of transgene expression variant || gene expression variant || transgene subcellular localization variant || protein interaction variant || organism metabolism processing variant || protein protein interaction variant || protein aggregation variant |
| Saposin | 1 | INHERITED FROM: transgene expression variant || increased pathogen survival || transgene expression reduced || level of transgene expression variant || pathogen load variant |
| Nuclear receptor ligand-binding domain | 1 | INHERITED FROM: dauer resistance to harsh conditions variant || lipid metabolism variant || gene expression level high || SDS sensitive dauer || fat content increased || transgene expression reduced || level of transgene expression variant || gene expression level reduced |
| Bet v1-like | 1 | INHERITED FROM: growth rate variant |
| Thioredoxin-like | 1 | INHERITED FROM: enzyme activity reduced || enzyme activity variant || organism electrophilic stress hypersensitive || organism stress response variant || cadmium hypersensitive || organism heat hypersensitive || paraquat response variant || organism environmental stimulus response variant |
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| LDH C-terminal domain-like | 0 | Direct |
| Thiolase-like | 0 | Direct |
| PurM C-terminal domain-like | 0 | Direct |
| Clathrin adaptor appendage domain | 0 | Direct |
| Aminoacid dehydrogenase-like, N-terminal domain | 0 | Direct |
| Restriction endonuclease-like | 0 | Direct |
| Blood coagulation inhibitor (disintegrin) | 0 | Direct |
| Thyroglobulin type-1 domain | 0 | Direct |
| PEP carboxykinase-like | 0 | Direct |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | Direct |
| Hedgehog/intein (Hint) domain | 0 | Direct |
| Ribokinase-like | 0 | Direct |
| Carbon-nitrogen hydrolase | 0 | Direct |
| DNA ligase/mRNA capping enzyme, catalytic domain | 0 | Direct |
| Intermediate filament protein, coiled coil region | 0 | Direct |
| Ribosomal proteins S24e, L23 and L15e | 0 | Direct |
| Carbonic anhydrase | 0 | Direct |
| Ferritin-like | 0 | Direct |
| Class I glutamine amidotransferase-like | 0 | Direct |
| TK C-terminal domain-like | 0 | Direct |
| Periplasmic binding protein-like II | 0 | Direct |
| eIF4e-like | 0 | Direct |
| PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | Direct |
| GINS helical bundle-like | 0 | Direct |
| SMAD/FHA domain | 0 | Direct |
| CO dehydrogenase molybdoprotein N-domain-like | 0 | Direct |
| Bacterial exopeptidase dimerisation domain | 0 | Direct |
| Aquaporin-like | 0 | Direct |
| GroEL-intermediate domain like | 0 | Direct |
| Chromo domain-like | 0 | Direct |
| PIN domain-like | 0 | Direct |
| ADP-ribosylation | 0 | Direct |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | Direct |
| Tubulin nucleotide-binding domain-like | 0 | Direct |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| F1F0 ATP synthase subunit C | 0 | Direct |
| Doublecortin (DC) | 0 | Direct |
| Ribosomal protein L1 | 0 | Direct |
| PYP-like sensor domain (PAS domain) | 0 | Direct |
| Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | Direct |
| PK beta-barrel domain-like | 0 | Direct |
| ISP domain | 0 | Direct |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
| alpha/beta knot | 0 | Direct |
| Cdc48 domain 2-like | 0 | Direct |
| LysM domain | 0 | Direct |
| 3-carboxy-cis,cis-mucoante lactonizing enzyme | 0 | Direct |
| PAP/OAS1 substrate-binding domain | 0 | Direct |
| Rudiment single hybrid motif | 0 | Direct |
| Pepsin inhibitor-3 | 0 | Direct |
| Glutathione synthetase ATP-binding domain-like | 0 | Direct |
| 2Fe-2S ferredoxin-like | 0 | Direct |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0 | Direct |
| PurM N-terminal domain-like | 0 | Direct |
| CRAL/TRIO N-terminal domain | 0 | Direct |
| BEACH domain | 0 | Direct |
| HSP40/DnaJ peptide-binding domain | 0 | Direct |
| PHM/PNGase F | 0 | Direct |
| Subtilisin-like | 0 | Direct |
| Calcium-dependent phosphotriesterase | 0 | Direct |
| GYF domain | 0 | Direct |
| YWTD domain | 0 | Direct |
| ENTH/VHS domain | 0 | Direct |
| MFPT repeat-like | 0 | Direct |
| MIR domain | 0 | Direct |
| Subdomain of clathrin and coatomer appendage domain | 0 | Direct |
| TGS-like | 0 | Direct |
| Cullin homology domain | 0 | Direct |
| beta-lactamase/transpeptidase-like | 0 | Direct |
| Formate/glycerate dehydrogenase catalytic domain-like | 0 | Direct |
| Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | Direct |
| Integrin alpha N-terminal domain | 0 | Direct |
| Outer arm dynein light chain 1 | 0 | Direct |
| Integrin domains | 0 | Direct |
| FF domain | 0 | Direct |
| Domain of poly(ADP-ribose) polymerase | 0 | Direct |
| SMAD MH1 domain | 0 | Direct |
| Zn-finger domain of Sec23/24 | 0 | Direct |
| SAND domain-like | 0 | Direct |
| Actin-like ATPase domain | 0 | Direct |
| Activating enzymes of the ubiquitin-like proteins | 0 | Direct |
| L-aspartase-like | 0 | Direct |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
| LEM domain | 0 | Direct |
| Cystatin/monellin | 0 | Direct |
| Nucleotidyltransferase | 0 | Direct |
| Hormone receptor domain | 0 | Direct |
| Annexin | 0 | Direct |
| SAICAR synthase-like | 0 | Direct |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
| t-snare proteins | 0 | Direct |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
| GHMP Kinase, C-terminal domain | 0 | Direct |
| Phosphoenolpyruvate/pyruvate domain | 0 | Direct |
| PreATP-grasp domain | 0 | Direct |
| Transducin (heterotrimeric G protein), gamma chain | 0 | Direct |
| Thiamin diphosphate-binding fold (THDP-binding) | 0 | Direct |
| Terpenoid cyclases/Protein prenyltransferases | 0 | Direct |
| Isocitrate/Isopropylmalate dehydrogenase-like | 0 | Direct |
| JAB1/MPN domain | 0 | Direct |
| PEP carboxykinase N-terminal domain | 0 | Direct |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | Direct |
| PP2C-like | 0 | Direct |
| Fibrinogen C-terminal domain-like | 0 | Direct |
| WWE domain | 0 | Direct |
| Carbohydrate phosphatase | 0 | Direct |
| Citrate synthase | 0 | Direct |
| Tricorn protease domain 2 | 0 | Direct |
| L30e-like | 0 | Direct |
| Polo-box domain | 0 | Direct |
| Ran binding protein zinc finger-like | 0 | Direct |
| Creatinase/prolidase N-terminal domain | 0 | Direct |
| Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0 | Direct |
| Glycolipid transfer protein, GLTP | 0 | Direct |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
| Tubby C-terminal domain-like | 0 | Direct |
| Oxysterol-binding protein-like | 0 | Direct |
| cAMP-binding domain-like | 0 | Direct |
| Cadherin-like | 0 | Direct |
| Invertebrate chitin-binding proteins | 0 | Direct |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | Direct |
| HSP90 C-terminal domain | 0 | Direct |
| GAS2 domain-like | 0 | Direct |
| Molybdenum cofactor-binding domain | 0 | Direct |
| Troponin coil-coiled subunits | 0 | Direct |
| DNA repair protein MutS, domain III | 0 | Direct |
| Elafin-like | 0 | Direct |
| SCP-like | 0 | Direct |
| Galactose mutarotase-like | 0 | Direct |
| alpha-catenin/vinculin-like | 0 | Direct |
| Sec7 domain | 0 | Direct |
| Single hybrid motif | 0 | Direct |
| MgtE membrane domain-like | 0 | Direct |
| Heme-dependent catalase-like | 0 | Direct |
| YbiA-like | 0 | Direct |
| Class II aaRS ABD-related | 0 | Direct |
| Band 7/SPFH domain | 0 | Direct |
| dsRNA-binding domain-like | 0 | Direct |
| Nucleoside diphosphate kinase, NDK | 0 | Direct |
| Profilin (actin-binding protein) | 0 | Direct |
| Purine and uridine phosphorylases | 0 | Direct |
| FAD-dependent thiol oxidase | 0 | Direct |
| HMG-box | 0 | Direct |
| Alpha-L RNA-binding motif | 0 | Direct |
| CBD9-like | 0 | Direct |
| S-adenosylmethionine synthetase | 0 | Direct |
| Spectrin repeat | 0 | Direct |
| HCP-like | 0 | Direct |
| MOSC N-terminal domain-like | 0 | Direct |
| Sec1/munc18-like (SM) proteins | 0 | Direct |
| Cation efflux protein cytoplasmic domain-like | 0 | Direct |
| Ribosomal L27 protein-like | 0 | Direct |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | Direct |
| Radical SAM enzymes | 0 | Direct |
| Families 57/38 glycoside transferase middle domain | 0 | Direct |
| Proton glutamate symport protein | 0 | Direct |
| Skp1 dimerisation domain-like | 0 | Direct |
| FtsH protease domain-like | 0 | Direct |
| Type II DNA topoisomerase | 0 | Direct |
| Second domain of FERM | 0 | Direct |
| Acid phosphatase/Vanadium-dependent haloperoxidase | 0 | Direct |
| Cytochrome c | 0 | Direct |
| Rap/Ran-GAP | 0 | Direct |
| VPS9 domain | 0 | Direct |
| Tubulin C-terminal domain-like | 0 | Direct |
| Cu,Zn superoxide dismutase-like | 0 | Direct |
| Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | Direct |
| ThrRS/AlaRS common domain | 0 | Direct |
| Arginase/deacetylase | 0 | Direct |
| SPOC domain-like | 0 | Direct |
| Insulin-like | 0 | Direct |
| SIS domain | 0 | Direct |
| GroES-like | 0 | Direct |
| lambda repressor-like DNA-binding domains | 0 | Direct |
| Sec63 N-terminal domain-like | 0 | Direct |
| Nop domain | 0 | Direct |
| Transducin (alpha subunit), insertion domain | 0 | Direct |
| PUA domain-like | 0 | Direct |
| DEATH domain | 0 | Direct |
| Putative DNA-binding domain | 0 | Direct |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | Direct |
| Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
| Heme-dependent peroxidases | 0 | Direct |
| PLC-like phosphodiesterases | 0 | Direct |
| Lamin A/C globular tail domain | 0 | Direct |
| Acyl-CoA dehydrogenase NM domain-like | 0 | Direct |
| Clc chloride channel | 0 | Direct |
| ValRS/IleRS/LeuRS editing domain | 0 | Direct |
| Ribulose-phoshate binding barrel | 0 | Direct |
| Composite domain of metallo-dependent hydrolases | 0 | Direct |
| RBP11-like subunits of RNA polymerase | 0 | Direct |
| Nucleoporin domain | 0 | Direct |
| WGR domain-like | 0 | Direct |
| Kringle-like | 0 | Direct |
| ARID-like | 0 | Direct |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
| ClpP/crotonase | 0 | Direct |
| AN1-like Zinc finger | 0 | Direct |
| Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | Direct |
| Zn-binding ribosomal proteins | 0 | Direct |
| Complement control module/SCR domain | 0 | Direct |
| Phosphoglucomutase, first 3 domains | 0 | Direct |
| Protease propeptides/inhibitors | 0 | Direct |
| Ribosomal protein L10-like | 0 | Direct |
| GAT-like domain | 0 | Direct |
| ArfGap/RecO-like zinc finger | 0 | Direct |
| Diaminopimelate epimerase-like | 0 | Direct |
| Translational machinery components | 0 | Direct |
| ALDH-like | 0 | Direct |
| Aldolase | 0 | Direct |
| Hect, E3 ligase catalytic domain | 0 | Direct |
| Carboxypeptidase regulatory domain-like | 0 | Direct |
| Mitochondrial carrier | 0 | Direct |
| R3H domain | 0 | Direct |
| 14-3-3 protein | 0 | Direct |
| HSP20-like chaperones | 0 | Direct |
| GroEL apical domain-like | 0 | Direct |
| CAD & PB1 domains | 0 | Direct |
| Surp module (SWAP domain) | 0 | Direct |
| PEBP-like | 0 | Direct |
| Galactose oxidase, central domain | 0 | Direct |
| Smc hinge domain | 0 | Direct |
| Phosphoglucomutase, C-terminal domain | 0 | Direct |
| Succinyl-CoA synthetase domains | 0 | Direct |
| Pentein | 0 | Direct |
| Helical domain of Sec23/24 | 0 | Direct |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Terpenoid synthases | 0 | Direct |
| Chitinase insertion domain | 0 | Direct |
| GroEL equatorial domain-like | 0 | Direct |
| SWIB/MDM2 domain | 0 | Direct |
| Small-conductance potassium channel | 0 | Direct |
| DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
| CO dehydrogenase ISP C-domain like | 0 | Direct |
| Hypothetical protein c14orf129, hspc210 | 0 | Direct |
| Chaperone J-domain | 0 | Direct |
| PABC (PABP) domain | 0 | Direct |
| PGBD-like | 0 | Direct |
| Tim10-like | 0 | Direct |
| Cullin repeat-like | 0 | Direct |
| PLP-binding barrel | 0 | Direct |
| P-loop containing nucleoside triphosphate hydrolases | 0.0000002719 | Direct |
| PH domain-like | 0.00009596 | Direct |
| Histone-fold | 0.0001964 | Direct |
| Protein kinase-like (PK-like) | 0.009874 | Inherited |
| PDZ domain-like | 0.01497 | Inherited |
| Nucleic acid-binding proteins | 0.02331 | Inherited |
| Periplasmic binding protein-like I | 0.02384 | Inherited |
| TPR-like | 0.0263 | Inherited |
| "Winged helix" DNA-binding domain | 0.03247 | Inherited |
| PapD-like | 0.03972 | Inherited |
| WD40 repeat-like | 0.05101 | Inherited |
| ARM repeat | 0.05182 | Inherited |
| SH2 domain | 0.05673 | Inherited |
| Homeodomain-like | 0.07731 | Inherited |
| Acetyl-CoA synthetase-like | 0.07972 | Inherited |
| Calponin-homology domain, CH-domain | 0.07972 | Inherited |
| Cyclin-like | 0.088 | Inherited |
| CCCH zinc finger | 0.09702 | Inherited |
| EGF/Laminin | 0.1062 | Inherited |
| Translation proteins | 0.1182 | Inherited |
| Galactose-binding domain-like | 0.126 | Inherited |
| Ankyrin repeat | 0.13 | Inherited |
| HLH, helix-loop-helix DNA-binding domain | 0.1473 | Inherited |
| Nucleotide cyclase | 0.1473 | Inherited |
| ABC transporter transmembrane region | 0.1473 | Inherited |
| RNI-like | 0.1553 | Inherited |
| Calcium ATPase, transmembrane domain M | 0.1577 | Inherited |
| Metal cation-transporting ATPase, ATP-binding domain N | 0.174 | Inherited |
| Regulator of G-protein signaling, RGS | 0.174 | Inherited |
| Calcium ATPase, transduction domain A | 0.1913 | Inherited |
| Class II aaRS and biotin synthetases | 0.1913 | Inherited |
| SH3-domain | 0.1972 | Inherited |
| E set domains | 0.2001 | Inherited |
| Quinoprotein alcohol dehydrogenase-like | 0.2104 | Inherited |
| DBL homology domain (DH-domain) | 0.2314 | Inherited |
| Multidrug efflux transporter AcrB transmembrane domain | 0.2325 | Inherited |
| (Trans)glycosidases | 0.277 | Inherited |
| Cytochrome P450 | 0.277 | Inherited |
| Multidrug resistance efflux transporter EmrE | 0.2789 | Inherited |
| BRCT domain | 0.2882 | Inherited |
| 6-phosphogluconate dehydrogenase C-terminal domain-like | 0.3063 | Inherited |
| Bromodomain | 0.3063 | Inherited |
| Nucleotidylyl transferase | 0.3309 | Inherited |
| POZ domain | 0.3327 | Inherited |
| SNARE-like | 0.335 | Inherited |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0.3403 | Inherited |
| Cysteine proteinases | 0.3417 | Inherited |
| RNA-binding domain, RBD | 0.3451 | Inherited |
| Ribosomal protein S5 domain 2-like | 0.3504 | Inherited |
| SAM/Pointed domain | 0.3542 | Inherited |
| Lipocalins | 0.3542 | Inherited |
| Growth factor receptor domain | 0.3788 | Inherited |
| Translation proteins SH3-like domain | 0.4029 | Inherited |
| Cation efflux protein transmembrane domain-like | 0.4029 | Inherited |
| Acid proteases | 0.4327 | Inherited |
| Nicotinic receptor ligand binding domain-like | 0.4544 | Inherited |
| Ubiquitin-like | 0.4649 | Inherited |
| FYVE/PHD zinc finger | 0.4661 | Inherited |
| Cysteine-rich domain | 0.4838 | Inherited |
| HAD-like | 0.4852 | Inherited |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.4908 | Inherited |
| Myosin rod fragments | 0.5252 | Inherited |
| DHS-like NAD/FAD-binding domain | 0.5252 | Inherited |
| PRTase-like | 0.5252 | Inherited |
| Calpain large subunit, middle domain (domain III) | 0.573 | Inherited |
| Ferredoxin reductase-like, C-terminal NADP-linked domain | 0.573 | Inherited |
| Riboflavin synthase domain-like | 0.573 | Inherited |
| WW domain | 0.5851 | Inherited |
| Cystine-knot cytokines | 0.5851 | Inherited |
| Sm-like ribonucleoproteins | 0.5851 | Inherited |
| FAD-linked reductases, C-terminal domain | 0.5851 | Inherited |
| GTPase activation domain, GAP | 0.5873 | Inherited |
| Voltage-gated potassium channels | 0.619 | Inherited |
| Seven-hairpin glycosidases | 0.6221 | Inherited |
| FAD/NAD(P)-binding domain | 0.624 | Inherited |
| SET domain | 0.6304 | Inherited |
| UBC-like | 0.6542 | Inherited |
| Lipovitellin-phosvitin complex, superhelical domain | 0.6786 | Inherited |
| Nucleotide-binding domain | 0.6786 | Inherited |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0.6786 | Inherited |
| KA1-like | 0.6786 | Inherited |
| Osmotin, thaumatin-like protein | 0.6786 | Inherited |
| MFS general substrate transporter | 0.6868 | Inherited |
| Clavaminate synthase-like | 0.7247 | Inherited |
| S15/NS1 RNA-binding domain | 0.7382 | Inherited |
| Frizzled cysteine-rich domain | 0.7382 | Inherited |
| 4Fe-4S ferredoxins | 0.7382 | Inherited |
| GST C-terminal domain-like | 0.7652 | Inherited |
| PAZ domain | 0.7984 | Inherited |
| Ribonuclease H-like | 0.8027 | Inherited |
| MIT domain | 0.8032 | Inherited |
| Glucocorticoid receptor-like (DNA-binding domain) | 0.8032 | Inherited |
| ADC-like | 0.8032 | Inherited |
| alpha/beta-Hydrolases | 0.813 | Inherited |
| Fibronectin type III | 0.8604 | Inherited |
| Leucine zipper domain | 0.9001 | Inherited |
| UBA-like | 0.9108 | Inherited |
| EF-hand | 0.9227 | Inherited |
| beta-beta-alpha zinc fingers | 0.9494 | Inherited |
| DNA/RNA polymerases | 0.9647 | Inherited |
| p53-like transcription factors | 0.9736 | Inherited |
| Ribonuclease PH domain 2-like | 0.9749 | Inherited |
| Immunoglobulin | 0.9992 | Inherited |
| CoA-dependent acyltransferases | 1 | Inherited |
| Cyclophilin-like | 1 | Inherited |
| Family A G protein-coupled receptor-like | 1 | Inherited |
| B-box zinc-binding domain | 1 | Inherited |
| Eukaryotic type KH-domain (KH-domain type I) | 1 | Inherited |
| FKBP-like | 1 | Inherited |
| F-box domain | 1 | Inherited |
| Ligand-binding domain in the NO signalling and Golgi transport | 1 | Inherited |
| RING/U-box | 1 | Inherited |
| Saposin | 1 | Inherited |
| Nuclear receptor ligand-binding domain | 1 | Inherited |
| Bet v1-like | 1 | Inherited |
| Thioredoxin-like | 1 | Inherited |
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Family(show details)
Family domains annotated to this WP term (Not in SDWP)
Highlighted in gray are those with FDR_all>0.001
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| Mammalian PLC | 0 | DIRECT |
| Armadillo repeat | 0 | DIRECT |
| CO dehydrogenase flavoprotein N-terminal domain-like | 0 | DIRECT |
| Filamin repeat (rod domain) | 0 | DIRECT |
| Poly(A) polymerase, PAP, C-terminal domain | 0 | DIRECT |
| Pancreatic carboxypeptidases | 0 | DIRECT |
| Pancreatic carboxypeptidase, activation domain | 0 | DIRECT |
| UBA domain | 0 | DIRECT |
| PhzC/PhzF-like | 0 | DIRECT |
| FHA domain | 0 | DIRECT |
| Type II DNA topoisomerase | 0 | DIRECT |
| Reprolysin-like | 0 | DIRECT |
| Chitinase insertion domain | 0 | DIRECT |
| NTF2-like | 0 | DIRECT |
| Hydantoinase (dihydropyrimidinase) | 0 | DIRECT |
| La domain | 0 | DIRECT |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| VHS domain | 0 | DIRECT |
| Anticodon-binding domain of Class II aaRS | 0 | DIRECT |
| Medium chain acyl-CoA dehydrogenase-like, C-terminal domain | 0 | DIRECT |
| Trunk domain of Sec23/24 | 0 | DIRECT |
| Cullin repeat | 0 | DIRECT |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | DIRECT |
| SWIRM domain | 0 | DIRECT |
| Actin/HSP70 | 0 | DIRECT |
| Polo-box duplicated region | 0 | DIRECT |
| Ngr ectodomain-like | 0 | DIRECT |
| MFPT repeat | 0 | DIRECT |
| Sec1/munc18-like (SM) proteins | 0 | DIRECT |
| PDZ domain | 0 | DIRECT |
| Cadherin | 0 | DIRECT |
| Nucleoside diphosphate kinase, NDK | 0 | DIRECT |
| Acyl-carrier protein (ACP) | 0 | DIRECT |
| Acylamino-acid-releasing enzyme, C-terminal donain | 0 | DIRECT |
| Succinyl-CoA synthetase domains | 0 | DIRECT |
| Branched-chain alpha-keto acid dehydrogenase Pyr module | 0 | DIRECT |
| Zn-finger domain of Sec23/24 | 0 | DIRECT |
| Glycolipid transfer protein, GLTP | 0 | DIRECT |
| Pleckstrin-homology domain (PH domain) | 0 | DIRECT |
| S-adenosylmethionine synthetase | 0 | DIRECT |
| Proprotein convertase P-domain | 0 | DIRECT |
| PABC (PABP) domain | 0 | DIRECT |
| Translational machinery components | 0 | DIRECT |
| Transducin (heterotrimeric G protein), gamma chain | 0 | DIRECT |
| Subtilases | 0 | DIRECT |
| BAR domain | 0 | DIRECT |
| Phoshoinositide 3-kinase (PI3K), catalytic domain | 0 | DIRECT |
| 14-3-3 protein | 0 | DIRECT |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
| beta-Lactamase/D-ala carboxypeptidase | 0 | DIRECT |
| GAS2 domain | 0 | DIRECT |
| Ran binding protein zinc finger-like | 0 | DIRECT |
| First domain of FERM | 0 | DIRECT |
| DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
| Aminoacid dehydrogenase-like, C-terminal domain | 0 | DIRECT |
| PP2C-like | 0 | DIRECT |
| Group II chaperonin (CCT, TRIC), ATPase domain | 0 | DIRECT |
| Bacterial exopeptidase dimerisation domain | 0 | DIRECT |
| Internalin LRR domain | 0 | DIRECT |
| Elafin-like | 0 | DIRECT |
| Hedgehog C-terminal (Hog) autoprocessing domain | 0 | DIRECT |
| Ribosomal protein L18 and S11 | 0 | DIRECT |
| Fibrinogen C-terminal domain-like | 0 | DIRECT |
| Biotinyl/lipoyl-carrier proteins and domains | 0 | DIRECT |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | DIRECT |
| Matrix metalloproteases, catalytic domain | 0 | DIRECT |
| Nop domain | 0 | DIRECT |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | DIRECT |
| MIR domain | 0 | DIRECT |
| Cdc48 domain 2-like | 0 | DIRECT |
| Third domain of FERM | 0 | DIRECT |
| DNA replication initiator (cdc21/cdc54) N-terminal domain | 0 | DIRECT |
| SMAD domain | 0 | DIRECT |
| Troponin I | 0 | DIRECT |
| Proton glutamate symport protein | 0 | DIRECT |
| Peptidylglycine alpha-hydroxylating monooxygenase, PHM | 0 | DIRECT |
| RecA protein-like (ATPase-domain) | 0 | DIRECT |
| WWE domain | 0 | DIRECT |
| XPF/Rad1/Mus81 nuclease | 0 | DIRECT |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Purine and uridine phosphorylases | 0 | DIRECT |
| Bactericidal permeability-increasing protein, BPI | 0 | DIRECT |
| alpha-catenin/vinculin | 0 | DIRECT |
| Thiolase-related | 0 | DIRECT |
| Oxysterol-binding protein | 0 | DIRECT |
| ARID domain | 0 | DIRECT |
| Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | DIRECT |
| Protein prenyltransferases | 0 | DIRECT |
| D-aminoacid oxidase-like | 0 | DIRECT |
| UDP-glucose pyrophosphorylase | 0 | DIRECT |
| Hsp90 middle domain | 0 | DIRECT |
| Phosphatidylethanolamine binding protein | 0 | DIRECT |
| Blood coagulation inhibitor (disintegrin) | 0 | DIRECT |
| Hormone receptor domain | 0 | DIRECT |
| Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta | 0 | DIRECT |
| Sterol carrier protein, SCP | 0 | DIRECT |
| Phoshoinositide 3-kinase (PI3K) helical domain | 0 | DIRECT |
| Reductases | 0 | DIRECT |
| Acyl-CoA thioesterase | 0 | DIRECT |
| LEM domain | 0 | DIRECT |
| POU-specific domain | 0 | DIRECT |
| Glycerophosphoryl diester phosphodiesterase | 0 | DIRECT |
| Nucleosome core histones | 0 | DIRECT |
| Arginine methyltransferase | 0 | DIRECT |
| PEP carboxykinase C-terminal domain | 0 | DIRECT |
| Cyclin | 0 | DIRECT |
| Insulin-like | 0 | DIRECT |
| Citrate synthase | 0 | DIRECT |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
| RNA-polymerase beta | 0 | DIRECT |
| Integrin domains | 0 | DIRECT |
| Sec63 C-terminal domain-like | 0 | DIRECT |
| BC ATP-binding domain-like | 0 | DIRECT |
| Carbonic anhydrase | 0 | DIRECT |
| Sir2 family of transcriptional regulators | 0 | DIRECT |
| alpha-mannosidase | 0 | DIRECT |
| SAM (sterile alpha motif) domain | 0 | DIRECT |
| Inositol monophosphatase/fructose-1,6-bisphosphatase-like | 0 | DIRECT |
| Heat shock protein 90, HSP90, N-terminal domain | 0 | DIRECT |
| FF domain | 0 | DIRECT |
| Ribonucleotide reductase-like | 0 | DIRECT |
| DEATH domain, DD | 0 | DIRECT |
| Doublecortin (DC) | 0 | DIRECT |
| beta 1,4 galactosyltransferase (b4GalT1) | 0 | DIRECT |
| HEAT repeat | 0 | DIRECT |
| Phosphoribosyltransferases (PRTases) | 0 | DIRECT |
| Linker histone H1/H5 | 0 | DIRECT |
| Phosphotyrosine-binding domain (PTB) | 0 | DIRECT |
| GHMP Kinase, N-terminal domain | 0 | DIRECT |
| Group II chaperonin (CCT, TRIC), apical domain | 0 | DIRECT |
| CoA-binding domain | 0 | DIRECT |
| Clathrin adaptor core protein | 0 | DIRECT |
| PLC-like (P variant) | 0 | DIRECT |
| Domain of poly(ADP-ribose) polymerase | 0 | DIRECT |
| Proteasome subunits | 0 | DIRECT |
| AAT-like | 0 | DIRECT |
| acyl-CoA oxidase C-terminal domains | 0 | DIRECT |
| DNA repair protein MutS, domain III | 0 | DIRECT |
| Spectrin repeat | 0 | DIRECT |
| Acireductone dioxygenase | 0 | DIRECT |
| PUA domain | 0 | DIRECT |
| Arfaptin, Rac-binding fragment | 0 | DIRECT |
| Glycerol kinase | 0 | DIRECT |
| PurM N-terminal domain-like | 0 | DIRECT |
| Cell cycle control phosphatase, catalytic domain | 0 | DIRECT |
| Glycogenin | 0 | DIRECT |
| Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain | 0 | DIRECT |
| Surp module (SWAP domain) | 0 | DIRECT |
| Ras-binding domain, RBD | 0 | DIRECT |
| cAMP-binding domain | 0 | DIRECT |
| GYF domain | 0 | DIRECT |
| Adenain-like | 0 | DIRECT |
| BC C-terminal domain-like | 0 | DIRECT |
| FtsH protease domain-like | 0 | DIRECT |
| RhoGDI-like | 0 | DIRECT |
| SCF ubiquitin ligase complex WHB domain | 0 | DIRECT |
| Myotubularin-like phosphatases | 0 | DIRECT |
| Inositol polyphosphate kinase (IPK) | 0 | DIRECT |
| ALDH-like | 0 | DIRECT |
| Intermediate filament protein, coiled coil region | 0 | DIRECT |
| Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain | 0 | DIRECT |
| alpha-Amylases, C-terminal beta-sheet domain | 0 | DIRECT |
| Cytoplasmic domain of inward rectifier potassium channel | 0 | DIRECT |
| 5' to 3' exonuclease catalytic domain | 0 | DIRECT |
| Class I glutamine amidotransferases (GAT) | 0 | DIRECT |
| Phosphoglucomutase, first 3 domains | 0 | DIRECT |
| Cullin homology domain | 0 | DIRECT |
| Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | DIRECT |
| p120GAP domain-like | 0 | DIRECT |
| Chromo domain | 0 | DIRECT |
| Type II chitinase | 0 | DIRECT |
| Anticodon-binding domain | 0 | DIRECT |
| CO dehydrogenase ISP C-domain like | 0 | DIRECT |
| LDH N-terminal domain-like | 0 | DIRECT |
| LysM domain | 0 | DIRECT |
| Calpain large subunit, catalytic domain (domain II) | 0 | DIRECT |
| BC N-terminal domain-like | 0 | DIRECT |
| HSP20 | 0 | DIRECT |
| AN1-like Zinc finger | 0 | DIRECT |
| CO dehydrogenase molybdoprotein N-domain-like | 0 | DIRECT |
| Fatty acid binding protein-like | 0 | DIRECT |
| MOSC N-terminal domain-like | 0 | DIRECT |
| Second domain of FERM | 0 | DIRECT |
| SAND domain | 0 | DIRECT |
| Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains | 0 | DIRECT |
| PDEase | 0 | DIRECT |
| NOL1/NOP2/sun | 0 | DIRECT |
| Histone deacetylase, HDAC | 0 | DIRECT |
| Biotin dependent carboxylase carboxyltransferase domain | 0 | DIRECT |
| Brix domain | 0 | DIRECT |
| Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | DIRECT |
| RNA-polymerase beta-prime | 0 | DIRECT |
| Regulator of chromosome condensation RCC1 | 0 | DIRECT |
| DPP6 N-terminal domain-like | 0 | DIRECT |
| Lamin A/C globular tail domain | 0 | DIRECT |
| Annexin | 0 | DIRECT |
| PurM C-terminal domain-like | 0 | DIRECT |
| Gamma-glutamyltranspeptidase-like | 0 | DIRECT |
| Skp1 dimerisation domain-like | 0 | DIRECT |
| Carboxypeptidase regulatory domain | 0 | DIRECT |
| Molybdenum cofactor-binding domain | 0 | DIRECT |
| Quinoprotein alcohol dehydrogenase-like | 0 | DIRECT |
| Group II chaperonin (CCT, TRIC), intermediate domain | 0 | DIRECT |
| SWIB/MDM2 domain | 0 | DIRECT |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | DIRECT |
| Class I aldolase | 0 | DIRECT |
| Phosphate binding protein-like | 0 | DIRECT |
| GAPDH-like | 0 | DIRECT |
| EGF-type module | 0 | DIRECT |
| Ubiquitin activating enzymes (UBA) | 0 | DIRECT |
| Poly(ADP-ribose) polymerase, C-terminal domain | 0 | DIRECT |
| Regulator of G-protein signaling, RGS | 0 | DIRECT |
| DEP domain | 0 | DIRECT |
| Profilin (actin-binding protein) | 0 | DIRECT |
| Pyk2-associated protein beta ARF-GAP domain | 0 | DIRECT |
| Band 7/SPFH domain | 0 | DIRECT |
| CUT domain | 0 | DIRECT |
| F1F0 ATP synthase subunit C | 0 | DIRECT |
| Mitochondrial carrier | 0 | DIRECT |
| Pepsin inhibitor-3 | 0 | DIRECT |
| U-box | 0 | DIRECT |
| Lactate & malate dehydrogenases, C-terminal domain | 0 | DIRECT |
| ets domain | 0 | DIRECT |
| DNA gyrase/MutL, N-terminal domain | 0 | DIRECT |
| Complement control module/SCR domain | 0 | DIRECT |
| Smc hinge domain | 0 | DIRECT |
| ATP-dependent protease Lon (La), catalytic domain | 0 | DIRECT |
| Lesion bypass DNA polymerase (Y-family), catalytic domain | 0 | DIRECT |
| YihX-like | 0 | DIRECT |
| CRAL/TRIO N-terminal domain | 0 | DIRECT |
| Hect, E3 ligase catalytic domain | 0 | DIRECT |
| acyl-CoA oxidase N-terminal domains | 0 | DIRECT |
| Crotonase-like | 0 | DIRECT |
| YbiA-like | 0 | DIRECT |
| DPP6 catalytic domain-like | 0 | DIRECT |
| PaaI/YdiI-like | 0 | DIRECT |
| YicI catalytic domain-like | 0 | DIRECT |
| Translation initiation factor eIF4e | 0 | DIRECT |
| Tetraspanin | 0 | DIRECT |
| Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain | 0 | DIRECT |
| Cofilin-like | 0 | DIRECT |
| Ferredoxin reductase FAD-binding domain-like | 0 | DIRECT |
| Hypothetical protein c14orf129, hspc210 | 0 | DIRECT |
| Ribosomal protein L1 | 0 | DIRECT |
| DNA gyrase/MutL, second domain | 0 | DIRECT |
| Alcohol dehydrogenase-like, N-terminal domain | 0 | DIRECT |
| Alcohol dehydrogenase-like, C-terminal domain | 0 | DIRECT |
| Ribokinase-like | 0 | DIRECT |
| HAT/Suf repeat | 0 | DIRECT |
| L30e/L7ae ribosomal proteins | 0 | DIRECT |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
| PEP carboxykinase N-terminal domain | 0 | DIRECT |
| Clc chloride channel | 0 | DIRECT |
| Double-stranded RNA-binding domain (dsRBD) | 0 | DIRECT |
| Class II glutamine amidotransferases | 0 | DIRECT |
| COMT-like | 0 | DIRECT |
| Myeloperoxidase-like | 0 | DIRECT |
| Glutaminase | 0 | DIRECT |
| Hydantoinase (dihydropyrimidinase), catalytic domain | 0 | DIRECT |
| MutT-like | 0 | DIRECT |
| HCDH C-domain-like | 0 | DIRECT |
| MIF4G domain-like | 0 | DIRECT |
| HSP90 C-terminal domain | 0 | DIRECT |
| 28-residue LRR | 0 | DIRECT |
| HMG-box | 0 | DIRECT |
| Tim10/DDP | 0 | DIRECT |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
| Rap/Ran-GAP | 0 | DIRECT |
| Helical domain of Sec23/24 | 0 | DIRECT |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
| Arylsulfatase | 0 | DIRECT |
| CAT-like | 0 | DIRECT |
| HD domain | 0 | DIRECT |
| HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
| Paired domain | 0 | DIRECT |
| LacY-like proton/sugar symporter | 0 | DIRECT |
| beta-sandwich domain of Sec23/24 | 0 | DIRECT |
| a tRNA synthase domain | 0 | DIRECT |
| Heme-dependent catalases | 0 | DIRECT |
| Erythroid transcription factor GATA-1 | 0 | DIRECT |
| Ubiquitin carboxyl-terminal hydrolase UCH-L | 0 | DIRECT |
| Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain | 0 | DIRECT |
| Amylase, catalytic domain | 0 | DIRECT |
| RNA editing terminal uridyl transferase 2, RET2, domain 2 | 0 | DIRECT |
| Inositol polyphosphate 5-phosphatase (IPP5) | 0 | DIRECT |
| Aquaporin-like | 0 | DIRECT |
| Thyroglobulin type-1 domain | 0 | DIRECT |
| Sec63 N-terminal domain | 0 | DIRECT |
| Epoxide hydrolase | 0 | DIRECT |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
| alpha-mannosidase, domain 2 | 0 | DIRECT |
| ValRS/IleRS/LeuRS editing domain | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
| BEACH domain | 0 | DIRECT |
| Calcium ATPase, transmembrane domain M | 0 | DIRECT |
| Branched-chain alpha-keto acid dehydrogenase PP module | 0 | DIRECT |
| Transducin (alpha subunit), insertion domain | 0 | DIRECT |
| Chaperone J-domain | 0 | DIRECT |
| Dimeric isocitrate & isopropylmalate dehydrogenases | 0 | DIRECT |
| Formate/glycerate dehydrogenases, NAD-domain | 0 | DIRECT |
| Tubulin, GTPase domain | 0 | DIRECT |
| Choline kinase | 0 | DIRECT |
| Single strand DNA-binding domain, SSB | 0 | DIRECT |
| Methionine aminopeptidase, insert domain | 0 | DIRECT |
| YWTD domain | 0 | DIRECT |
| Poly(A) polymerase, PAP, middle domain | 0 | DIRECT |
| L-aminoacid/polyamine oxidase | 0 | DIRECT |
| Serum paraoxonase/arylesterase 1, PON1 | 0 | DIRECT |
| SMAD MH1 domain | 0 | DIRECT |
| 1,3-glucuronyltransferase | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
| Sec7 domain | 0 | DIRECT |
| IF2B-like | 0 | DIRECT |
| Cu,Zn superoxide dismutase-like | 0 | DIRECT |
| D-aminoacid oxidase, N-terminal domain | 0 | DIRECT |
| Glycosyl transferases group 1 | 0 | DIRECT |
| WGR domain | 0 | DIRECT |
| AMPK-beta glycogen binding domain-like | 0 | DIRECT |
| Tubulin, C-terminal domain | 0 | DIRECT |
| Laminin G-like module | 0 | DIRECT |
| PDI-like | 0 | DIRECT |
| 2Fe-2S ferredoxin domains from multidomain proteins | 0 | DIRECT |
| NHL repeat | 0 | DIRECT |
| Small-conductance potassium channel | 0 | DIRECT |
| t-snare proteins | 0 | DIRECT |
| alpha-mannosidase, C-terminal domain | 0 | DIRECT |
| Adenosine/AMP deaminase | 0 | DIRECT |
| FAD-dependent thiol oxidase | 0 | DIRECT |
| Poly(A) polymerase, PAP, N-terminal domain | 0 | DIRECT |
| Hexokinase | 0 | DIRECT |
| Cation efflux protein cytoplasmic domain-like | 0 | DIRECT |
| Clathrin coat assembly domain | 0 | DIRECT |
| Tandem AAA-ATPase domain | 0.000458 | DIRECT |
| Protein kinases, catalytic subunit | 0.02148 | INHERITED FROM: second messenger mediated signaling variant || oxygen response variant || protein phosphorylation variant || kinase activity reduced || conflicting sensory integration variant || pathogen induced gene expression variant || aldicarb response variant || metal response variant || protein expression variant || protein modification variant || positive chemotaxis variant || egg laying response to food variant || alkaline pH chemotaxis variant || protein phosphorylation reduced || chemical response variant || copper response variant || protein subcellular localization variant || drug induced gene expression variant || lipid synthesis increased || anoxia resistant |
| ABC transporter ATPase domain-like | 0.04734 | INHERITED FROM: metal response variant || colchicine hypersensitive || RNAi response variant || cadmium response variant |
| Homeodomain | 0.04778 | INHERITED FROM: carbon dioxide response variant || ectopic expression transgene || level of transgene expression variant || organism metabolism processing variant || sexually dimorphic physiology variant || carbon dioxide avoidance variant |
| G proteins | 0.04824 | INHERITED FROM: protein phosphorylation variant || osmotic integrity variant || carbon dioxide response variant || bacterially unswollen || aldicarb response variant || protein metabolism variant || fat content variant || organism environmental stimulus response variant || organism metabolism processing variant || protein subcellular localization variant || drug induced gene expression variant || carbon dioxide avoidance variant |
| WD40-repeat | 0.06241 | INHERITED FROM: late larval arrest || antimicrobial gene expression variant || dauer defective || osmotic avoidance variant || protein aggregation induced behavior variant || organism metabolism processing variant |
| L-arabinose binding protein-like | 0.07971 | INHERITED FROM: lithium chemotaxis defective || anion positive chemotaxis defective || cation positive chemotaxis variant || chemotaxis variant || magnesium chemotaxis defective || cation positive chemotaxis defective || organism environmental stimulus response variant || iodide chemotaxis variant || alkaline pH chemotaxis variant || bromide chemotaxis defective || bromide chemotaxis variant || chemical response variant || chemosensory response variant || iodide chemotaxis defective || anion positive chemotaxis variant |
| SH2 domain | 0.08363 | INHERITED FROM: protein expression variant || level of protein expression variant || protein expression reduced |
| MSP-like | 0.08378 | INHERITED FROM: dauer metabolism variant || dauer lifespan extended || developmental growth variant || larval arrest || dauer lifespan variant || lipid metabolism variant || fat content variant || slow growth || larval growth variant |
| Acetyl-CoA synthetase-like | 0.09548 | INHERITED FROM: lipid metabolism variant |
| Calponin-homology domain, CH-domain | 0.09548 | INHERITED FROM: protein degradation variant |
| CCCH zinc finger | 0.1145 | INHERITED FROM: transgene expression variant || gene expression variant || ectopic expression transgene || mRNA expression ectopic |
| Canonical RBD | 0.1155 | INHERITED FROM: sick || late larval arrest || antimicrobial gene expression variant || mRNA export variant || organism metabolism processing variant || no induction of antimicrobial peptide expression after infection || innate immune response variant || RNA expression variant || RNA processing variant || starvation induced apoptosis variant |
| Tetratricopeptide repeat (TPR) | 0.1475 | INHERITED FROM: antibody subcellular localization variant || organism metabolism processing variant |
| Cold shock DNA-binding domain-like | 0.164 | INHERITED FROM: sick || mRNA surveillance defective || nonsense mRNA accumulation |
| HLH, helix-loop-helix DNA-binding domain | 0.1828 | INHERITED FROM: hypoxia response variant || ectopic expression transgene || aqueous positive chemotaxis defective || lysine chemotaxis defective || gene expression level reduced || RNA expression variant |
| Adenylyl and guanylyl cyclase catalytic domain | 0.1828 | INHERITED FROM: lithium chemotaxis defective || second messenger mediated signaling variant || anion positive chemotaxis defective || carbon dioxide response variant || chemotaxis variant || magnesium chemotaxis defective || AWC odorant chemotaxis defective || cation positive chemotaxis defective || AWC odorant chemotaxis variant || organism environmental stimulus response variant || osmotic avoidance variant || positive chemotaxis variant || iodide chemotaxis variant || alkaline pH chemotaxis variant || bromide chemotaxis defective || diacetyl chemotaxis variant || bromide chemotaxis variant || chemosensory response variant || iodide chemotaxis defective |
| Ankyrin repeat | 0.2064 | INHERITED FROM: organism heat response variant || odorant negative chemotaxis defective || octanol chemotaxis defective || octanol chemotaxis variant |
| Calcium ATPase, transduction domain A | 0.2139 | INHERITED FROM: organism environmental stimulus response variant || drug hypersensitive || nicotine hypersensitive |
| ABC transporter transmembrane region | 0.2399 | INHERITED FROM: metal response variant || organism environmental stimulus response variant || colchicine hypersensitive || RNAi response variant || cadmium response variant |
| Histone lysine methyltransferases | 0.2551 | INHERITED FROM: histone methylation variant || somatic transgene silencing variant || ectopic expression transgene || life span variant || protein expression variant || mRNA expression variant || protein modification variant || ectopic expression antibody || RNAi response variant || protein methylation variant || maintenance of gene silencing variant |
| DBL homology domain (DH-domain) | 0.2551 | INHERITED FROM: bacterially unswollen || aldicarb response variant || organism pathogen response variant || organism environmental stimulus response variant || pathogen resistance increased |
| Elongation factors | 0.2551 | INHERITED FROM: proteasome core activity variant || protein phosphorylation variant || mRNA levels reduced || protein phosphorylation increased || protein modification variant || mRNA levels increased || protein protein interaction variant || protein aggregation variant |
| Class I aminoacyl-tRNA synthetases (RS), catalytic domain | 0.2551 | INHERITED FROM: oxygen response variant || hypoxia resistant || gene expression variant || hypoxia response variant || transgene expression increased || antimicrobial gene expression variant || paraquat response variant || organism environmental stimulus response variant || organism metabolism processing variant || paraquat resistant || innate immune response variant |
| Extended PAW domain | 0.2551 | INHERITED FROM: pattern of transgene expression variant || transgene subcellular localization variant || protein interaction variant || protein protein interaction variant || protein aggregation variant |
| Pepsin-like | 0.2551 | INHERITED FROM: transgene expression variant || pattern of transgene expression variant || osmotic integrity variant || gene expression variant || transgene subcellular localization variant || protein interaction variant || organism metabolism processing variant || hypoosmotic shock hypersensitive || protein protein interaction variant || protein aggregation variant |
| SH3-domain | 0.26 | INHERITED FROM: aldicarb response variant || protein expression variant || protein expression reduced |
| Dual specificity phosphatase-like | 0.2774 | INHERITED FROM: gene expression variant || transgene expression reduced || level of transgene expression variant || organism metabolism processing variant |
| Acetylcholinesterase-like | 0.285 | INHERITED FROM: enzyme activity reduced || enzyme activity variant || acetylcholinesterase activity variant || acetylcholinesterase reduced |
| Metal cation-transporting ATPase, ATP-binding domain N | 0.3021 | INHERITED FROM: organism environmental stimulus response variant || drug hypersensitive || nicotine hypersensitive |
| FYVE, a phosphatidylinositol-3-phosphate binding domain | 0.3303 | INHERITED FROM: aldicarb resistant || acetylcholinesterase inhibitor resistant |
| Bromodomain | 0.3303 | INHERITED FROM: organism UV hypersensitive || sick || anesthetic response variant || organism UV response variant || organism stress response variant || acute functional tolerance to alcohol defective || drug adaptation variant || ethanol resistant || anesthetic resistant |
| 6-phosphogluconate dehydrogenase-like, N-terminal domain | 0.3303 | INHERITED FROM: lipid metabolism variant || fat content variant |
| Multidrug efflux transporter AcrB transmembrane domain | 0.3325 | INHERITED FROM: egg integrity defective early emb || chemotaxis variant || embryo osmotic integrity defective early emb || odorant chemosensory response variant || odorant positive chemotaxis defective || positive chemotaxis defective |
| Extended AAA-ATPase domain | 0.336 | INHERITED FROM: sick || protein expression increased || life span variant || spontaneous mutation rate increased |
| Growth factor receptor domain | 0.3596 | INHERITED FROM: chemotaxis variant |
| FAD/NAD-linked reductases, N-terminal and central domains | 0.3596 | INHERITED FROM: paraquat response variant || organism oxidative stress response variant || pesticide response variant |
| Cytochrome P450 | 0.3698 | INHERITED FROM: metal response variant || cadmium response variant |
| Meta-cation ATPase, catalytic domain P | 0.3917 | INHERITED FROM: organism environmental stimulus response variant || nicotine hypersensitive |
| Sm motif of small nuclear ribonucleoproteins, SNRNP | 0.3917 | INHERITED FROM: sick || pattern of transgene expression variant || life span variant || pattern protein expression variant || protein subcellular localization variant || protein protein interaction variant || protein aggregation variant |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.4509 | INHERITED FROM: cholinergic agonist resistant || mechanosensation variant || selenium response variant || organism environmental stimulus response variant || nicotine resistant || drug response variant || hypoosmotic shock hypersensitive || DMPP response variant || chemical response variant || aqueous chemosensory response variant || sodium chloride chemotaxis variant || antihelmintic response variant |
| Pumilio repeat | 0.4626 | INHERITED FROM: protein expression ectopic |
| GABA-aminotransferase-like | 0.4626 | INHERITED FROM: fat content reduced |
| Cation efflux protein transmembrane domain-like | 0.5015 | INHERITED FROM: metal response variant || cadmium hypersensitive || manganese response variant || cadmium response variant || manganese toxicity resistant |
| Protein kinase cysteine-rich domain (cys2, phorbol-binding domain) | 0.5036 | INHERITED FROM: drug resistant || antimicrobial gene expression variant || odorant positive chemotaxis variant || nose touch variant || organism pathogen response variant || odorant chemosensory response variant || protein subcellular localization variant || drug induced gene expression variant |
| Glutathione S-transferase (GST), N-terminal domain | 0.5118 | INHERITED FROM: enzyme activity reduced || enzyme activity variant || organism electrophilic stress hypersensitive || organism stress response variant || cadmium hypersensitive || organism heat hypersensitive || paraquat response variant || organism environmental stimulus response variant || cadmium response variant |
| PHD domain | 0.5333 | INHERITED FROM: organism UV hypersensitive || organism UV response variant || ectopic expression transgene || RNAi response variant || protein methylation variant || RNAi resistant |
| Myosin rod fragments | 0.5461 | INHERITED FROM: drug resistant |
| BCR-homology GTPase activation domain (BH-domain) | 0.5637 | INHERITED FROM: protein expression reduced |
| Nicotinic receptor ligand binding domain-like | 0.5895 | INHERITED FROM: cholinergic agonist resistant || mechanosensation variant || selenium response variant || organism environmental stimulus response variant || nicotine resistant || drug response variant || hypoosmotic shock hypersensitive || DMPP response variant || chemical response variant || aqueous chemosensory response variant || sodium chloride chemotaxis variant || antihelmintic response variant |
| Myb/SANT domain | 0.5902 | INHERITED FROM: growth rate variant |
| Gastric lipase | 0.5902 | INHERITED FROM: lipid metabolism variant || fat content variant |
| Calpain large subunit, middle domain (domain III) | 0.5902 | INHERITED FROM: protein degradation variant || protein metabolism variant || metabolic pathway variant |
| I set domains | 0.5919 | INHERITED FROM: protein degradation variant || aldicarb response variant || organism environmental stimulus response variant || metabolic pathway variant || aldicarb resistant || growth rate variant |
| Papain-like | 0.6171 | INHERITED FROM: transgene expression variant || pattern of transgene expression variant || osmotic integrity variant || gene expression variant || protein interaction variant || organism metabolism processing variant || hypoosmotic shock hypersensitive || protein protein interaction variant || protein aggregation variant |
| WW domain | 0.6241 | INHERITED FROM: maintenance of gene silencing variant |
| Pyridoxal-dependent decarboxylase | 0.6402 | INHERITED FROM: carbon dioxide response variant || drug response variant || egg laying response to drug variant || carbon dioxide avoidance variant |
| Class I alpha-1;2-mannosidase, catalytic domain | 0.6402 | INHERITED FROM: extended life span || protein protein interaction variant || protein aggregation variant |
| UBC-related | 0.6689 | INHERITED FROM: transgene expression variant || pattern of transgene expression variant || gene expression variant || transgene subcellular localization variant || protein interaction variant || late larval arrest || organism metabolism processing variant || protein protein interaction variant || protein aggregation variant |
| Synaptotagmin-like (S variant) | 0.6899 | INHERITED FROM: drug resistant || acetylcholinesterase inhibitor response variant || pattern protein expression variant || protein subcellular localization variant || acetylcholinesterase inhibitor resistant |
| Osmotin, thaumatin-like protein | 0.6939 | INHERITED FROM: metal response variant || cadmium hypersensitive || cadmium response variant |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0.6939 | INHERITED FROM: organism pathogen response variant || life span variant || organism environmental stimulus response variant || pathogen susceptibility increased |
| Lipovitellin-phosvitin complex, superhelical domain | 0.6939 | INHERITED FROM: organism pathogen response variant || life span variant || organism environmental stimulus response variant || pathogen susceptibility increased |
| Ubiquitin carboxyl-terminal hydrolase, UCH | 0.7199 | INHERITED FROM: transgene expression variant || pattern of transgene expression variant || gene expression variant || protein interaction variant || organism metabolism processing variant || protein protein interaction variant || protein aggregation variant |
| BTB/POZ domain | 0.7465 | INHERITED FROM: chemical hypersensitive || L1 arrest || early larval arrest || protein aggregation induced behavior variant || resistant to protein aggregation induced paralysis || chemical response variant |
| EF-hand modules in multidomain proteins | 0.7514 | INHERITED FROM: protein expression variant |
| Frizzled cysteine-rich domain | 0.7514 | INHERITED FROM: antibody staining variant || transgene expression reduced |
| Transforming growth factor (TGF)-beta | 0.7514 | INHERITED FROM: nicotine response variant || transgene expression reduced || level of transgene expression variant || drug response variant || levamisole response variant |
| MIT domain | 0.8122 | INHERITED FROM: protein interaction variant || protein protein interaction variant || protein aggregation variant |
| Bacterial lipase | 0.8122 | INHERITED FROM: lipid metabolism variant || fat content variant |
| Cdc48 N-terminal domain-like | 0.8122 | INHERITED FROM: protein interaction variant || protein metabolism variant || metabolic pathway variant || protein protein interaction variant || protein aggregation variant |
| H-NOX domain | 0.8122 | INHERITED FROM: carbon dioxide response variant || carbon dioxide avoidance variant |
| Ubiquitin-related | 0.8278 | INHERITED FROM: transgene expression variant || hypersensitive to protein aggregation induced paralysis || protein interaction variant || organism metabolism processing variant || protein protein interaction variant || protein aggregation variant |
| Voltage-gated potassium channels | 0.8507 | INHERITED FROM: protein degradation variant || serotonin response variant || protein metabolism variant || AWA odorant chemotaxis variant || adrenergic receptor antagonist response variant || growth rate variant |
| FAD-linked reductases, N-terminal domain | 0.8587 | INHERITED FROM: shortened life span |
| PAZ domain | 0.8904 | INHERITED FROM: 21U RNA expression variant || RNAi enhanced || mRNA levels increased || RNAi response variant || siRNA expression variant || maintenance of gene silencing variant || RNA expression variant |
| LIM domain | 0.8944 | INHERITED FROM: protein degradation variant || level of protein expression variant || protein expression reduced |
| Glutathione S-transferase (GST), C-terminal domain | 0.9146 | INHERITED FROM: enzyme activity reduced || enzyme activity variant || organism electrophilic stress hypersensitive || organism stress response variant || cadmium hypersensitive || organism environmental stimulus response variant || cadmium response variant |
| Fibronectin type III | 0.918 | INHERITED FROM: protein degradation variant |
| Leucine zipper domain | 0.9376 | INHERITED FROM: pore forming toxin response variant || mRNA levels reduced || transgene expression reduced || level of transgene expression variant || pathogen susceptibility increased |
| DnaQ-like 3'-5' exonuclease | 0.9425 | INHERITED FROM: RNAi response variant |
| Calmodulin-like | 0.9641 | INHERITED FROM: transgene subcellular localization variant || protein interaction variant || protein protein interaction variant || protein aggregation variant |
| RING finger domain, C3HC4 | 0.9688 | INHERITED FROM: pattern of transgene expression variant || transgene subcellular localization variant || protein interaction variant || organism metabolism processing variant || protein protein interaction variant || protein aggregation variant |
| Nuclear receptor ligand-binding domain | 0.9854 | INHERITED FROM: dauer resistance to harsh conditions variant || lipid metabolism variant || gene expression level high || SDS sensitive dauer || fat content increased || transgene expression reduced || gene expression level reduced |
| NagD-like | 0.9854 | INHERITED FROM: dauer formation variant || dauer constitutive |
| Ribonuclease PH domain 2-like | 0.9854 | INHERITED FROM: early larval arrest |
| Ribonuclease PH domain 1-like | 0.9854 | INHERITED FROM: early larval arrest |
| F-box domain | 1 | INHERITED FROM: protein aggregation induced behavior variant || resistant to protein aggregation induced paralysis |
| FKBP immunophilin/proline isomerase | 1 | INHERITED FROM: pattern of transgene expression variant || transgene subcellular localization variant || protein interaction variant || protein protein interaction variant || protein aggregation variant |
| Glutathione peroxidase-like | 1 | INHERITED FROM: paraquat response variant || pesticide response variant |
| B-box zinc-binding domain | 1 | INHERITED FROM: transgene expression variant || gene expression variant || transgene subcellular localization variant || protein interaction variant || protein protein interaction variant || protein aggregation variant |
| Rhodopsin-like | 1 | INHERITED FROM: aqueous adaptation defective || locomotion rate serotonin variant || biogenic amine receptor antagonist resistant || serotonin induced pumping variant || serotonin response variant || organism pathogen response variant || male tail curling serotonin variant || serotonin resistant || serotonin induced fat reduction variant || serotonin hypersensitive || egg laying response to drug variant || drug withdrawal response variant |
| C-type lectin domain | 1 | INHERITED FROM: pathogen induced death increased |
| N-acetyl transferase, NAT | 1 | INHERITED FROM: ectopic expression transgene |
| Cyclophilin (peptidylprolyl isomerase) | 1 | INHERITED FROM: transgene expression variant || pattern of transgene expression variant || transgene subcellular localization variant || protein interaction variant || protein protein interaction variant || protein aggregation variant |
| Nuclear receptor | 1 | INHERITED FROM: dauer resistance to harsh conditions variant || gene expression level high || SDS sensitive dauer || fat content increased || transgene expression reduced || gene expression level reduced |
| Choline/Carnitine O-acyltransferase | 1 | INHERITED FROM: lipid metabolism variant || fat content variant |
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| Mammalian PLC | 0 | Direct |
| Armadillo repeat | 0 | Direct |
| CO dehydrogenase flavoprotein N-terminal domain-like | 0 | Direct |
| Filamin repeat (rod domain) | 0 | Direct |
| Poly(A) polymerase, PAP, C-terminal domain | 0 | Direct |
| Pancreatic carboxypeptidases | 0 | Direct |
| Pancreatic carboxypeptidase, activation domain | 0 | Direct |
| UBA domain | 0 | Direct |
| PhzC/PhzF-like | 0 | Direct |
| FHA domain | 0 | Direct |
| Type II DNA topoisomerase | 0 | Direct |
| Reprolysin-like | 0 | Direct |
| Chitinase insertion domain | 0 | Direct |
| NTF2-like | 0 | Direct |
| Hydantoinase (dihydropyrimidinase) | 0 | Direct |
| La domain | 0 | Direct |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| VHS domain | 0 | Direct |
| Anticodon-binding domain of Class II aaRS | 0 | Direct |
| Medium chain acyl-CoA dehydrogenase-like, C-terminal domain | 0 | Direct |
| Trunk domain of Sec23/24 | 0 | Direct |
| Cullin repeat | 0 | Direct |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | Direct |
| SWIRM domain | 0 | Direct |
| Actin/HSP70 | 0 | Direct |
| Polo-box duplicated region | 0 | Direct |
| Ngr ectodomain-like | 0 | Direct |
| MFPT repeat | 0 | Direct |
| Sec1/munc18-like (SM) proteins | 0 | Direct |
| PDZ domain | 0 | Direct |
| Cadherin | 0 | Direct |
| Nucleoside diphosphate kinase, NDK | 0 | Direct |
| Acyl-carrier protein (ACP) | 0 | Direct |
| Acylamino-acid-releasing enzyme, C-terminal donain | 0 | Direct |
| Succinyl-CoA synthetase domains | 0 | Direct |
| Branched-chain alpha-keto acid dehydrogenase Pyr module | 0 | Direct |
| Zn-finger domain of Sec23/24 | 0 | Direct |
| Glycolipid transfer protein, GLTP | 0 | Direct |
| Pleckstrin-homology domain (PH domain) | 0 | Direct |
| S-adenosylmethionine synthetase | 0 | Direct |
| Proprotein convertase P-domain | 0 | Direct |
| PABC (PABP) domain | 0 | Direct |
| Translational machinery components | 0 | Direct |
| Transducin (heterotrimeric G protein), gamma chain | 0 | Direct |
| Subtilases | 0 | Direct |
| BAR domain | 0 | Direct |
| Phoshoinositide 3-kinase (PI3K), catalytic domain | 0 | Direct |
| 14-3-3 protein | 0 | Direct |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
| beta-Lactamase/D-ala carboxypeptidase | 0 | Direct |
| GAS2 domain | 0 | Direct |
| Ran binding protein zinc finger-like | 0 | Direct |
| First domain of FERM | 0 | Direct |
| DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
| Aminoacid dehydrogenase-like, C-terminal domain | 0 | Direct |
| PP2C-like | 0 | Direct |
| Group II chaperonin (CCT, TRIC), ATPase domain | 0 | Direct |
| Bacterial exopeptidase dimerisation domain | 0 | Direct |
| Internalin LRR domain | 0 | Direct |
| Elafin-like | 0 | Direct |
| Hedgehog C-terminal (Hog) autoprocessing domain | 0 | Direct |
| Ribosomal protein L18 and S11 | 0 | Direct |
| Fibrinogen C-terminal domain-like | 0 | Direct |
| Biotinyl/lipoyl-carrier proteins and domains | 0 | Direct |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | Direct |
| Matrix metalloproteases, catalytic domain | 0 | Direct |
| Nop domain | 0 | Direct |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | Direct |
| MIR domain | 0 | Direct |
| Cdc48 domain 2-like | 0 | Direct |
| Third domain of FERM | 0 | Direct |
| DNA replication initiator (cdc21/cdc54) N-terminal domain | 0 | Direct |
| SMAD domain | 0 | Direct |
| Troponin I | 0 | Direct |
| Proton glutamate symport protein | 0 | Direct |
| Peptidylglycine alpha-hydroxylating monooxygenase, PHM | 0 | Direct |
| RecA protein-like (ATPase-domain) | 0 | Direct |
| WWE domain | 0 | Direct |
| XPF/Rad1/Mus81 nuclease | 0 | Direct |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Purine and uridine phosphorylases | 0 | Direct |
| Bactericidal permeability-increasing protein, BPI | 0 | Direct |
| alpha-catenin/vinculin | 0 | Direct |
| Thiolase-related | 0 | Direct |
| Oxysterol-binding protein | 0 | Direct |
| ARID domain | 0 | Direct |
| Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | Direct |
| Protein prenyltransferases | 0 | Direct |
| D-aminoacid oxidase-like | 0 | Direct |
| UDP-glucose pyrophosphorylase | 0 | Direct |
| Hsp90 middle domain | 0 | Direct |
| Phosphatidylethanolamine binding protein | 0 | Direct |
| Blood coagulation inhibitor (disintegrin) | 0 | Direct |
| Hormone receptor domain | 0 | Direct |
| Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta | 0 | Direct |
| Sterol carrier protein, SCP | 0 | Direct |
| Phoshoinositide 3-kinase (PI3K) helical domain | 0 | Direct |
| Reductases | 0 | Direct |
| Acyl-CoA thioesterase | 0 | Direct |
| LEM domain | 0 | Direct |
| POU-specific domain | 0 | Direct |
| Glycerophosphoryl diester phosphodiesterase | 0 | Direct |
| Nucleosome core histones | 0 | Direct |
| Arginine methyltransferase | 0 | Direct |
| PEP carboxykinase C-terminal domain | 0 | Direct |
| Cyclin | 0 | Direct |
| Insulin-like | 0 | Direct |
| Citrate synthase | 0 | Direct |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
| RNA-polymerase beta | 0 | Direct |
| Integrin domains | 0 | Direct |
| Sec63 C-terminal domain-like | 0 | Direct |
| BC ATP-binding domain-like | 0 | Direct |
| Carbonic anhydrase | 0 | Direct |
| Sir2 family of transcriptional regulators | 0 | Direct |
| alpha-mannosidase | 0 | Direct |
| SAM (sterile alpha motif) domain | 0 | Direct |
| Inositol monophosphatase/fructose-1,6-bisphosphatase-like | 0 | Direct |
| Heat shock protein 90, HSP90, N-terminal domain | 0 | Direct |
| FF domain | 0 | Direct |
| Ribonucleotide reductase-like | 0 | Direct |
| DEATH domain, DD | 0 | Direct |
| Doublecortin (DC) | 0 | Direct |
| beta 1,4 galactosyltransferase (b4GalT1) | 0 | Direct |
| HEAT repeat | 0 | Direct |
| Phosphoribosyltransferases (PRTases) | 0 | Direct |
| Linker histone H1/H5 | 0 | Direct |
| Phosphotyrosine-binding domain (PTB) | 0 | Direct |
| GHMP Kinase, N-terminal domain | 0 | Direct |
| Group II chaperonin (CCT, TRIC), apical domain | 0 | Direct |
| CoA-binding domain | 0 | Direct |
| Clathrin adaptor core protein | 0 | Direct |
| PLC-like (P variant) | 0 | Direct |
| Domain of poly(ADP-ribose) polymerase | 0 | Direct |
| Proteasome subunits | 0 | Direct |
| AAT-like | 0 | Direct |
| acyl-CoA oxidase C-terminal domains | 0 | Direct |
| DNA repair protein MutS, domain III | 0 | Direct |
| Spectrin repeat | 0 | Direct |
| Acireductone dioxygenase | 0 | Direct |
| PUA domain | 0 | Direct |
| Arfaptin, Rac-binding fragment | 0 | Direct |
| Glycerol kinase | 0 | Direct |
| PurM N-terminal domain-like | 0 | Direct |
| Cell cycle control phosphatase, catalytic domain | 0 | Direct |
| Glycogenin | 0 | Direct |
| Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain | 0 | Direct |
| Surp module (SWAP domain) | 0 | Direct |
| Ras-binding domain, RBD | 0 | Direct |
| cAMP-binding domain | 0 | Direct |
| GYF domain | 0 | Direct |
| Adenain-like | 0 | Direct |
| BC C-terminal domain-like | 0 | Direct |
| FtsH protease domain-like | 0 | Direct |
| RhoGDI-like | 0 | Direct |
| SCF ubiquitin ligase complex WHB domain | 0 | Direct |
| Myotubularin-like phosphatases | 0 | Direct |
| Inositol polyphosphate kinase (IPK) | 0 | Direct |
| ALDH-like | 0 | Direct |
| Intermediate filament protein, coiled coil region | 0 | Direct |
| Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain | 0 | Direct |
| alpha-Amylases, C-terminal beta-sheet domain | 0 | Direct |
| Cytoplasmic domain of inward rectifier potassium channel | 0 | Direct |
| 5' to 3' exonuclease catalytic domain | 0 | Direct |
| Class I glutamine amidotransferases (GAT) | 0 | Direct |
| Phosphoglucomutase, first 3 domains | 0 | Direct |
| Cullin homology domain | 0 | Direct |
| Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | Direct |
| p120GAP domain-like | 0 | Direct |
| Chromo domain | 0 | Direct |
| Type II chitinase | 0 | Direct |
| Anticodon-binding domain | 0 | Direct |
| CO dehydrogenase ISP C-domain like | 0 | Direct |
| LDH N-terminal domain-like | 0 | Direct |
| LysM domain | 0 | Direct |
| Calpain large subunit, catalytic domain (domain II) | 0 | Direct |
| BC N-terminal domain-like | 0 | Direct |
| HSP20 | 0 | Direct |
| AN1-like Zinc finger | 0 | Direct |
| CO dehydrogenase molybdoprotein N-domain-like | 0 | Direct |
| Fatty acid binding protein-like | 0 | Direct |
| MOSC N-terminal domain-like | 0 | Direct |
| Second domain of FERM | 0 | Direct |
| SAND domain | 0 | Direct |
| Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains | 0 | Direct |
| PDEase | 0 | Direct |
| NOL1/NOP2/sun | 0 | Direct |
| Histone deacetylase, HDAC | 0 | Direct |
| Biotin dependent carboxylase carboxyltransferase domain | 0 | Direct |
| Brix domain | 0 | Direct |
| Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | Direct |
| RNA-polymerase beta-prime | 0 | Direct |
| Regulator of chromosome condensation RCC1 | 0 | Direct |
| DPP6 N-terminal domain-like | 0 | Direct |
| Lamin A/C globular tail domain | 0 | Direct |
| Annexin | 0 | Direct |
| PurM C-terminal domain-like | 0 | Direct |
| Gamma-glutamyltranspeptidase-like | 0 | Direct |
| Skp1 dimerisation domain-like | 0 | Direct |
| Carboxypeptidase regulatory domain | 0 | Direct |
| Molybdenum cofactor-binding domain | 0 | Direct |
| Quinoprotein alcohol dehydrogenase-like | 0 | Direct |
| Group II chaperonin (CCT, TRIC), intermediate domain | 0 | Direct |
| SWIB/MDM2 domain | 0 | Direct |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | Direct |
| Class I aldolase | 0 | Direct |
| Phosphate binding protein-like | 0 | Direct |
| GAPDH-like | 0 | Direct |
| EGF-type module | 0 | Direct |
| Ubiquitin activating enzymes (UBA) | 0 | Direct |
| Poly(ADP-ribose) polymerase, C-terminal domain | 0 | Direct |
| Regulator of G-protein signaling, RGS | 0 | Direct |
| DEP domain | 0 | Direct |
| Profilin (actin-binding protein) | 0 | Direct |
| Pyk2-associated protein beta ARF-GAP domain | 0 | Direct |
| Band 7/SPFH domain | 0 | Direct |
| CUT domain | 0 | Direct |
| F1F0 ATP synthase subunit C | 0 | Direct |
| Mitochondrial carrier | 0 | Direct |
| Pepsin inhibitor-3 | 0 | Direct |
| U-box | 0 | Direct |
| Lactate & malate dehydrogenases, C-terminal domain | 0 | Direct |
| ets domain | 0 | Direct |
| DNA gyrase/MutL, N-terminal domain | 0 | Direct |
| Complement control module/SCR domain | 0 | Direct |
| Smc hinge domain | 0 | Direct |
| ATP-dependent protease Lon (La), catalytic domain | 0 | Direct |
| Lesion bypass DNA polymerase (Y-family), catalytic domain | 0 | Direct |
| YihX-like | 0 | Direct |
| CRAL/TRIO N-terminal domain | 0 | Direct |
| Hect, E3 ligase catalytic domain | 0 | Direct |
| acyl-CoA oxidase N-terminal domains | 0 | Direct |
| Crotonase-like | 0 | Direct |
| YbiA-like | 0 | Direct |
| DPP6 catalytic domain-like | 0 | Direct |
| PaaI/YdiI-like | 0 | Direct |
| YicI catalytic domain-like | 0 | Direct |
| Translation initiation factor eIF4e | 0 | Direct |
| Tetraspanin | 0 | Direct |
| Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain | 0 | Direct |
| Cofilin-like | 0 | Direct |
| Ferredoxin reductase FAD-binding domain-like | 0 | Direct |
| Hypothetical protein c14orf129, hspc210 | 0 | Direct |
| Ribosomal protein L1 | 0 | Direct |
| DNA gyrase/MutL, second domain | 0 | Direct |
| Alcohol dehydrogenase-like, N-terminal domain | 0 | Direct |
| Alcohol dehydrogenase-like, C-terminal domain | 0 | Direct |
| Ribokinase-like | 0 | Direct |
| HAT/Suf repeat | 0 | Direct |
| L30e/L7ae ribosomal proteins | 0 | Direct |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
| PEP carboxykinase N-terminal domain | 0 | Direct |
| Clc chloride channel | 0 | Direct |
| Double-stranded RNA-binding domain (dsRBD) | 0 | Direct |
| Class II glutamine amidotransferases | 0 | Direct |
| COMT-like | 0 | Direct |
| Myeloperoxidase-like | 0 | Direct |
| Glutaminase | 0 | Direct |
| Hydantoinase (dihydropyrimidinase), catalytic domain | 0 | Direct |
| MutT-like | 0 | Direct |
| HCDH C-domain-like | 0 | Direct |
| MIF4G domain-like | 0 | Direct |
| HSP90 C-terminal domain | 0 | Direct |
| 28-residue LRR | 0 | Direct |
| HMG-box | 0 | Direct |
| Tim10/DDP | 0 | Direct |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
| Rap/Ran-GAP | 0 | Direct |
| Helical domain of Sec23/24 | 0 | Direct |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
| Arylsulfatase | 0 | Direct |
| CAT-like | 0 | Direct |
| HD domain | 0 | Direct |
| HSP40/DnaJ peptide-binding domain | 0 | Direct |
| Paired domain | 0 | Direct |
| LacY-like proton/sugar symporter | 0 | Direct |
| beta-sandwich domain of Sec23/24 | 0 | Direct |
| a tRNA synthase domain | 0 | Direct |
| Heme-dependent catalases | 0 | Direct |
| Erythroid transcription factor GATA-1 | 0 | Direct |
| Ubiquitin carboxyl-terminal hydrolase UCH-L | 0 | Direct |
| Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain | 0 | Direct |
| Amylase, catalytic domain | 0 | Direct |
| RNA editing terminal uridyl transferase 2, RET2, domain 2 | 0 | Direct |
| Inositol polyphosphate 5-phosphatase (IPP5) | 0 | Direct |
| Aquaporin-like | 0 | Direct |
| Thyroglobulin type-1 domain | 0 | Direct |
| Sec63 N-terminal domain | 0 | Direct |
| Epoxide hydrolase | 0 | Direct |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
| alpha-mannosidase, domain 2 | 0 | Direct |
| ValRS/IleRS/LeuRS editing domain | 0 | Direct |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
| BEACH domain | 0 | Direct |
| Calcium ATPase, transmembrane domain M | 0 | Direct |
| Branched-chain alpha-keto acid dehydrogenase PP module | 0 | Direct |
| Transducin (alpha subunit), insertion domain | 0 | Direct |
| Chaperone J-domain | 0 | Direct |
| Dimeric isocitrate & isopropylmalate dehydrogenases | 0 | Direct |
| Formate/glycerate dehydrogenases, NAD-domain | 0 | Direct |
| Tubulin, GTPase domain | 0 | Direct |
| Choline kinase | 0 | Direct |
| Single strand DNA-binding domain, SSB | 0 | Direct |
| Methionine aminopeptidase, insert domain | 0 | Direct |
| YWTD domain | 0 | Direct |
| Poly(A) polymerase, PAP, middle domain | 0 | Direct |
| L-aminoacid/polyamine oxidase | 0 | Direct |
| Serum paraoxonase/arylesterase 1, PON1 | 0 | Direct |
| SMAD MH1 domain | 0 | Direct |
| 1,3-glucuronyltransferase | 0 | Direct |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
| Sec7 domain | 0 | Direct |
| IF2B-like | 0 | Direct |
| Cu,Zn superoxide dismutase-like | 0 | Direct |
| D-aminoacid oxidase, N-terminal domain | 0 | Direct |
| Glycosyl transferases group 1 | 0 | Direct |
| WGR domain | 0 | Direct |
| AMPK-beta glycogen binding domain-like | 0 | Direct |
| Tubulin, C-terminal domain | 0 | Direct |
| Laminin G-like module | 0 | Direct |
| PDI-like | 0 | Direct |
| 2Fe-2S ferredoxin domains from multidomain proteins | 0 | Direct |
| NHL repeat | 0 | Direct |
| Small-conductance potassium channel | 0 | Direct |
| t-snare proteins | 0 | Direct |
| alpha-mannosidase, C-terminal domain | 0 | Direct |
| Adenosine/AMP deaminase | 0 | Direct |
| FAD-dependent thiol oxidase | 0 | Direct |
| Poly(A) polymerase, PAP, N-terminal domain | 0 | Direct |
| Hexokinase | 0 | Direct |
| Cation efflux protein cytoplasmic domain-like | 0 | Direct |
| Clathrin coat assembly domain | 0 | Direct |
| Tandem AAA-ATPase domain | 0.000458 | Direct |
| Protein kinases, catalytic subunit | 0.02148 | Inherited |
| ABC transporter ATPase domain-like | 0.04734 | Inherited |
| Homeodomain | 0.04778 | Inherited |
| G proteins | 0.04824 | Inherited |
| WD40-repeat | 0.06241 | Inherited |
| L-arabinose binding protein-like | 0.07971 | Inherited |
| SH2 domain | 0.08363 | Inherited |
| MSP-like | 0.08378 | Inherited |
| Acetyl-CoA synthetase-like | 0.09548 | Inherited |
| Calponin-homology domain, CH-domain | 0.09548 | Inherited |
| CCCH zinc finger | 0.1145 | Inherited |
| Canonical RBD | 0.1155 | Inherited |
| Tetratricopeptide repeat (TPR) | 0.1475 | Inherited |
| Cold shock DNA-binding domain-like | 0.164 | Inherited |
| HLH, helix-loop-helix DNA-binding domain | 0.1828 | Inherited |
| Adenylyl and guanylyl cyclase catalytic domain | 0.1828 | Inherited |
| Ankyrin repeat | 0.2064 | Inherited |
| Calcium ATPase, transduction domain A | 0.2139 | Inherited |
| ABC transporter transmembrane region | 0.2399 | Inherited |
| Histone lysine methyltransferases | 0.2551 | Inherited |
| DBL homology domain (DH-domain) | 0.2551 | Inherited |
| Elongation factors | 0.2551 | Inherited |
| Class I aminoacyl-tRNA synthetases (RS), catalytic domain | 0.2551 | Inherited |
| Extended PAW domain | 0.2551 | Inherited |
| Pepsin-like | 0.2551 | Inherited |
| SH3-domain | 0.26 | Inherited |
| Dual specificity phosphatase-like | 0.2774 | Inherited |
| Acetylcholinesterase-like | 0.285 | Inherited |
| Metal cation-transporting ATPase, ATP-binding domain N | 0.3021 | Inherited |
| FYVE, a phosphatidylinositol-3-phosphate binding domain | 0.3303 | Inherited |
| Bromodomain | 0.3303 | Inherited |
| 6-phosphogluconate dehydrogenase-like, N-terminal domain | 0.3303 | Inherited |
| Multidrug efflux transporter AcrB transmembrane domain | 0.3325 | Inherited |
| Extended AAA-ATPase domain | 0.336 | Inherited |
| Growth factor receptor domain | 0.3596 | Inherited |
| FAD/NAD-linked reductases, N-terminal and central domains | 0.3596 | Inherited |
| Cytochrome P450 | 0.3698 | Inherited |
| Meta-cation ATPase, catalytic domain P | 0.3917 | Inherited |
| Sm motif of small nuclear ribonucleoproteins, SNRNP | 0.3917 | Inherited |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.4509 | Inherited |
| Pumilio repeat | 0.4626 | Inherited |
| GABA-aminotransferase-like | 0.4626 | Inherited |
| Cation efflux protein transmembrane domain-like | 0.5015 | Inherited |
| Protein kinase cysteine-rich domain (cys2, phorbol-binding domain) | 0.5036 | Inherited |
| Glutathione S-transferase (GST), N-terminal domain | 0.5118 | Inherited |
| PHD domain | 0.5333 | Inherited |
| Myosin rod fragments | 0.5461 | Inherited |
| BCR-homology GTPase activation domain (BH-domain) | 0.5637 | Inherited |
| Nicotinic receptor ligand binding domain-like | 0.5895 | Inherited |
| Myb/SANT domain | 0.5902 | Inherited |
| Gastric lipase | 0.5902 | Inherited |
| Calpain large subunit, middle domain (domain III) | 0.5902 | Inherited |
| I set domains | 0.5919 | Inherited |
| Papain-like | 0.6171 | Inherited |
| WW domain | 0.6241 | Inherited |
| Pyridoxal-dependent decarboxylase | 0.6402 | Inherited |
| Class I alpha-1;2-mannosidase, catalytic domain | 0.6402 | Inherited |
| UBC-related | 0.6689 | Inherited |
| Synaptotagmin-like (S variant) | 0.6899 | Inherited |
| Osmotin, thaumatin-like protein | 0.6939 | Inherited |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0.6939 | Inherited |
| Lipovitellin-phosvitin complex, superhelical domain | 0.6939 | Inherited |
| Ubiquitin carboxyl-terminal hydrolase, UCH | 0.7199 | Inherited |
| BTB/POZ domain | 0.7465 | Inherited |
| EF-hand modules in multidomain proteins | 0.7514 | Inherited |
| Frizzled cysteine-rich domain | 0.7514 | Inherited |
| Transforming growth factor (TGF)-beta | 0.7514 | Inherited |
| MIT domain | 0.8122 | Inherited |
| Bacterial lipase | 0.8122 | Inherited |
| Cdc48 N-terminal domain-like | 0.8122 | Inherited |
| H-NOX domain | 0.8122 | Inherited |
| Ubiquitin-related | 0.8278 | Inherited |
| Voltage-gated potassium channels | 0.8507 | Inherited |
| FAD-linked reductases, N-terminal domain | 0.8587 | Inherited |
| PAZ domain | 0.8904 | Inherited |
| LIM domain | 0.8944 | Inherited |
| Glutathione S-transferase (GST), C-terminal domain | 0.9146 | Inherited |
| Fibronectin type III | 0.918 | Inherited |
| Leucine zipper domain | 0.9376 | Inherited |
| DnaQ-like 3'-5' exonuclease | 0.9425 | Inherited |
| Calmodulin-like | 0.9641 | Inherited |
| RING finger domain, C3HC4 | 0.9688 | Inherited |
| Nuclear receptor ligand-binding domain | 0.9854 | Inherited |
| NagD-like | 0.9854 | Inherited |
| Ribonuclease PH domain 2-like | 0.9854 | Inherited |
| Ribonuclease PH domain 1-like | 0.9854 | Inherited |
| F-box domain | 1 | Inherited |
| FKBP immunophilin/proline isomerase | 1 | Inherited |
| Glutathione peroxidase-like | 1 | Inherited |
| B-box zinc-binding domain | 1 | Inherited |
| Rhodopsin-like | 1 | Inherited |
| C-type lectin domain | 1 | Inherited |
| N-acetyl transferase, NAT | 1 | Inherited |
| Cyclophilin (peptidylprolyl isomerase) | 1 | Inherited |
| Nuclear receptor | 1 | Inherited |
| Choline/Carnitine O-acyltransferase | 1 | Inherited |
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A presence/absence matrix is generated using protein domain
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Supra-domain (including individual superfamily)
(show details)
Supra-domains annotated to this WP term (Not in SPWP)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
| Elafin-like | 0 | DIRECT |
| Carbohydrate phosphatase | 0 | DIRECT |
| ArfGap/RecO-like zinc finger | 0 | DIRECT |
| Nucleoporin domain | 0 | DIRECT |
| ClpP/crotonase | 0 | DIRECT |
| MOSC N-terminal domain-like | 0 | DIRECT |
| PP2C-like | 0 | DIRECT |
| Band 7/SPFH domain | 0 | DIRECT |
| GAT-like domain | 0 | DIRECT |
| Bacterial exopeptidase dimerisation domain | 0 | DIRECT |
| Aquaporin-like | 0 | DIRECT |
| PreATP-grasp domain | 0 | DIRECT |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| 3-carboxy-cis,cis-mucoante lactonizing enzyme | 0 | DIRECT |
| Profilin (actin-binding protein) | 0 | DIRECT |
| Hect, E3 ligase catalytic domain | 0 | DIRECT |
| TGS-like | 0 | DIRECT |
| Troponin coil-coiled subunits | 0 | DIRECT |
| Tricorn protease domain 2 | 0 | DIRECT |
| Thiamin diphosphate-binding fold (THDP-binding) | 0 | DIRECT |
| Purine and uridine phosphorylases | 0 | DIRECT |
| DNA repair protein MutS, domain III | 0 | DIRECT |
| Protease propeptides/inhibitors | 0 | DIRECT |
| Nucleoside diphosphate kinase, NDK | 0 | DIRECT |
| DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
| Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
| Aminoacid dehydrogenase-like, N-terminal domain | 0 | DIRECT |
| CO dehydrogenase ISP C-domain like | 0 | DIRECT |
| Ribosomal proteins S24e, L23 and L15e | 0 | DIRECT |
| Mitochondrial carrier | 0 | DIRECT |
| Intermediate filament protein, coiled coil region | 0 | DIRECT |
| Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
| Citrate synthase | 0 | DIRECT |
| PLP-binding barrel | 0 | DIRECT |
| HSP20-like chaperones | 0 | DIRECT |
| Class I glutamine amidotransferase-like | 0 | DIRECT |
| Lamin A/C globular tail domain | 0 | DIRECT |
| Subtilisin-like | 0 | DIRECT |
| Ran binding protein zinc finger-like | 0 | DIRECT |
| Heme-dependent peroxidases | 0 | DIRECT |
| Arginase/deacetylase | 0 | DIRECT |
| Tim10-like | 0 | DIRECT |
| YbiA-like | 0 | DIRECT |
| Molybdenum cofactor-binding domain | 0 | DIRECT |
| WGR domain-like | 0 | DIRECT |
| Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | DIRECT |
| Creatinase/prolidase N-terminal domain | 0 | DIRECT |
| ADP-ribosylation | 0 | DIRECT |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0 | DIRECT |
| Galactose oxidase, central domain | 0 | DIRECT |
| Sec63 N-terminal domain-like | 0 | DIRECT |
| Integrin domains | 0 | DIRECT |
| Ribosomal protein L1 | 0 | DIRECT |
| PUA domain-like | 0 | DIRECT |
| Acyl-CoA dehydrogenase NM domain-like | 0 | DIRECT |
| Pepsin inhibitor-3 | 0 | DIRECT |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
| Cadherin-like | 0 | DIRECT |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | DIRECT |
| F1F0 ATP synthase subunit C | 0 | DIRECT |
| Radical SAM enzymes | 0 | DIRECT |
| Sec1/munc18-like (SM) proteins | 0 | DIRECT |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| PIN domain-like | 0 | DIRECT |
| MIR domain | 0 | DIRECT |
| Thiolase-like | 0 | DIRECT |
| FF domain | 0 | DIRECT |
| Proton glutamate symport protein | 0 | DIRECT |
| Glycolipid transfer protein, GLTP | 0 | DIRECT |
| Isocitrate/Isopropylmalate dehydrogenase-like | 0 | DIRECT |
| Second domain of FERM | 0 | DIRECT |
| dsRNA-binding domain-like | 0 | DIRECT |
| PABC (PABP) domain | 0 | DIRECT |
| Insulin-like | 0 | DIRECT |
| Ribosomal protein L10-like | 0 | DIRECT |
| Fibrinogen C-terminal domain-like | 0 | DIRECT |
| Translational machinery components | 0 | DIRECT |
| Terpenoid cyclases/Protein prenyltransferases | 0 | DIRECT |
| Phosphoenolpyruvate/pyruvate domain | 0 | DIRECT |
| PK beta-barrel domain-like | 0 | DIRECT |
| Alpha-L RNA-binding motif | 0 | DIRECT |
| Clc chloride channel | 0 | DIRECT |
| Cation efflux protein cytoplasmic domain-like | 0 | DIRECT |
| ARID-like | 0 | DIRECT |
| PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | DIRECT |
| Blood coagulation inhibitor (disintegrin) | 0 | DIRECT |
| PEP carboxykinase N-terminal domain | 0 | DIRECT |
| GroEL equatorial domain-like | 0 | DIRECT |
| L-aspartase-like | 0 | DIRECT |
| LysM domain | 0 | DIRECT |
| SCP-like | 0 | DIRECT |
| Succinyl-CoA synthetase domains | 0 | DIRECT |
| Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | DIRECT |
| FtsH protease domain-like | 0 | DIRECT |
| SIS domain | 0 | DIRECT |
| eIF4e-like | 0 | DIRECT |
| DEATH domain | 0 | DIRECT |
| Chaperone J-domain | 0 | DIRECT |
| Sec7 domain | 0 | DIRECT |
| t-snare proteins | 0 | DIRECT |
| Terpenoid synthases | 0 | DIRECT |
| Rap/Ran-GAP | 0 | DIRECT |
| Clathrin adaptor appendage domain | 0 | DIRECT |
| Zn-binding ribosomal proteins | 0 | DIRECT |
| Oxysterol-binding protein-like | 0 | DIRECT |
| Galactose mutarotase-like | 0 | DIRECT |
| BEACH domain | 0 | DIRECT |
| JAB1/MPN domain | 0 | DIRECT |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
| 2Fe-2S ferredoxin-like | 0 | DIRECT |
| Class II aaRS ABD-related | 0 | DIRECT |
| RBP11-like subunits of RNA polymerase | 0 | DIRECT |
| SAICAR synthase-like | 0 | DIRECT |
| Nop domain | 0 | DIRECT |
| Cdc48 domain 2-like | 0 | DIRECT |
| CRAL/TRIO N-terminal domain | 0 | DIRECT |
| Cullin repeat-like | 0 | DIRECT |
| Hormone receptor domain | 0 | DIRECT |
| Putative DNA-binding domain | 0 | DIRECT |
| Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0 | DIRECT |
| Helical domain of Sec23/24 | 0 | DIRECT |
| Restriction endonuclease-like | 0 | DIRECT |
| Ribulose-phoshate binding barrel | 0 | DIRECT |
| GAS2 domain-like | 0 | DIRECT |
| Skp1 dimerisation domain-like | 0 | DIRECT |
| Doublecortin (DC) | 0 | DIRECT |
| PYP-like sensor domain (PAS domain) | 0 | DIRECT |
| Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | DIRECT |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
| PEP carboxykinase-like | 0 | DIRECT |
| Cytochrome c | 0 | DIRECT |
| Spectrin repeat | 0 | DIRECT |
| alpha-catenin/vinculin-like | 0 | DIRECT |
| GINS helical bundle-like | 0 | DIRECT |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
| R3H domain | 0 | DIRECT |
| Hypothetical protein c14orf129, hspc210 | 0 | DIRECT |
| TK C-terminal domain-like | 0 | DIRECT |
| CAD & PB1 domains | 0 | DIRECT |
| GYF domain | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
| Actin-like ATPase domain | 0 | DIRECT |
| Subdomain of clathrin and coatomer appendage domain | 0 | DIRECT |
| AN1-like Zinc finger | 0 | DIRECT |
| PEBP-like | 0 | DIRECT |
| Aldolase | 0 | DIRECT |
| Cullin homology domain | 0 | DIRECT |
| WWE domain | 0 | DIRECT |
| Domain of poly(ADP-ribose) polymerase | 0 | DIRECT |
| Zn-finger domain of Sec23/24 | 0 | DIRECT |
| Chitinase insertion domain | 0 | DIRECT |
| Complement control module/SCR domain | 0 | DIRECT |
| DNA ligase/mRNA capping enzyme, catalytic domain | 0 | DIRECT |
| ALDH-like | 0 | DIRECT |
| L30e-like | 0 | DIRECT |
| SAND domain-like | 0 | DIRECT |
| Nucleotidyltransferase | 0 | DIRECT |
| CO dehydrogenase molybdoprotein N-domain-like | 0 | DIRECT |
| ThrRS/AlaRS common domain | 0 | DIRECT |
| CBD9-like | 0 | DIRECT |
| Phosphoglucomutase, first 3 domains | 0 | DIRECT |
| PHM/PNGase F | 0 | DIRECT |
| GroEL-intermediate domain like | 0 | DIRECT |
| Acid phosphatase/Vanadium-dependent haloperoxidase | 0 | DIRECT |
| Annexin | 0 | DIRECT |
| ISP domain | 0 | DIRECT |
| HSP90 C-terminal domain | 0 | DIRECT |
| Invertebrate chitin-binding proteins | 0 | DIRECT |
| SPOC domain-like | 0 | DIRECT |
| Carbon-nitrogen hydrolase | 0 | DIRECT |
| Activating enzymes of the ubiquitin-like proteins | 0 | DIRECT |
| Ferritin-like | 0 | DIRECT |
| Cu,Zn superoxide dismutase-like | 0 | DIRECT |
| Type II DNA topoisomerase | 0 | DIRECT |
| PGBD-like | 0 | DIRECT |
| ValRS/IleRS/LeuRS editing domain | 0 | DIRECT |
| Ribokinase-like | 0 | DIRECT |
| Integrin alpha N-terminal domain | 0 | DIRECT |
| PLC-like phosphodiesterases | 0 | DIRECT |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | DIRECT |
| Glutathione synthetase ATP-binding domain-like | 0 | DIRECT |
| Smc hinge domain | 0 | DIRECT |
| Formate/glycerate dehydrogenase catalytic domain-like | 0 | DIRECT |
| SWIB/MDM2 domain | 0 | DIRECT |
| alpha/beta knot | 0 | DIRECT |
| Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
| GHMP Kinase, C-terminal domain | 0 | DIRECT |
| 14-3-3 protein | 0 | DIRECT |
| MgtE membrane domain-like | 0 | DIRECT |
| Ribosomal L27 protein-like | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
| FAD-dependent thiol oxidase | 0 | DIRECT |
| Heme-dependent catalase-like | 0 | DIRECT |
| SMAD MH1 domain | 0 | DIRECT |
| Transducin (heterotrimeric G protein), gamma chain | 0 | DIRECT |
| HMG-box | 0 | DIRECT |
| ENTH/VHS domain | 0 | DIRECT |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
| Surp module (SWAP domain) | 0 | DIRECT |
| Hedgehog/intein (Hint) domain | 0 | DIRECT |
| Rudiment single hybrid motif | 0 | DIRECT |
| PurM C-terminal domain-like | 0 | DIRECT |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
| Single hybrid motif | 0 | DIRECT |
| SMAD/FHA domain | 0 | DIRECT |
| Thyroglobulin type-1 domain | 0 | DIRECT |
| Tubulin nucleotide-binding domain-like | 0 | DIRECT |
| Families 57/38 glycoside transferase middle domain | 0 | DIRECT |
| Polo-box domain | 0 | DIRECT |
| VPS9 domain | 0 | DIRECT |
| Chromo domain-like | 0 | DIRECT |
| GroEL apical domain-like | 0 | DIRECT |
| Tubulin C-terminal domain-like | 0 | DIRECT |
| lambda repressor-like DNA-binding domains | 0 | DIRECT |
| Carboxypeptidase regulatory domain-like | 0 | DIRECT |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | DIRECT |
| Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | DIRECT |
| Periplasmic binding protein-like II | 0 | DIRECT |
| cAMP-binding domain-like | 0 | DIRECT |
| S-adenosylmethionine synthetase | 0 | DIRECT |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | DIRECT |
| Kringle-like | 0 | DIRECT |
| LEM domain | 0 | DIRECT |
| YWTD domain | 0 | DIRECT |
| LDH C-terminal domain-like | 0 | DIRECT |
| GroES-like | 0 | DIRECT |
| Small-conductance potassium channel | 0 | DIRECT |
| Outer arm dynein light chain 1 | 0 | DIRECT |
| Calcium-dependent phosphotriesterase | 0 | DIRECT |
| beta-lactamase/transpeptidase-like | 0 | DIRECT |
| Carbonic anhydrase | 0 | DIRECT |
| Cystatin/monellin | 0 | DIRECT |
| Diaminopimelate epimerase-like | 0 | DIRECT |
| PurM N-terminal domain-like | 0 | DIRECT |
| HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
| PAP/OAS1 substrate-binding domain | 0 | DIRECT |
| Tubby C-terminal domain-like | 0 | DIRECT |
| Pentein | 0 | DIRECT |
| Transducin (alpha subunit), insertion domain | 0 | DIRECT |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | DIRECT |
| HCP-like | 0 | DIRECT |
| MFPT repeat-like | 0 | DIRECT |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
| P-loop containing nucleoside triphosphate hydrolases | 0.0000002175 | DIRECT |
| PH domain-like | 0.00007823 | DIRECT |
| Histone-fold | 0.0001604 | DIRECT |
| Protein kinase-like (PK-like) | 0.008435 | INHERITED FROM: conflicting sensory integration variant || organism environmental stimulus response variant || colchicine resistant || lipid synthesis increased || second messenger mediated signaling variant || anoxia resistant || chemical response variant || protein phosphorylation variant || aldicarb response variant || protein phosphorylation reduced || positive chemotaxis variant || alkaline pH chemotaxis variant || protein subcellular localization variant || drug induced gene expression variant || pathogen induced gene expression variant || kinase activity reduced || metal response variant || organism osmostic stress hypersensitive || egg laying response to food variant || transgene expression reduced || life span variant || protein expression variant |
| PDZ domain-like | 0.01288 | INHERITED FROM: aldicarb response variant || drug resistant || acetylcholinesterase inhibitor response variant || protein expression variant |
| Nucleic acid-binding proteins | 0.02027 | INHERITED FROM: mRNA surveillance defective || hypoxia resistant || nonsense mRNA accumulation || hydroxyurea response variant || hydroxyurea hypersensitive || sick |
| Periplasmic binding protein-like I | 0.02075 | INHERITED FROM: organism environmental stimulus response variant || aqueous positive chemotaxis variant || aqueous chemosensory response variant || second messenger mediated signaling variant || lithium chemotaxis defective || chemical response variant || diacetyl chemotaxis variant || bromide chemotaxis variant || iodide chemotaxis defective || AWC odorant chemotaxis defective || alkaline pH chemotaxis variant || magnesium chemotaxis defective || iodide chemotaxis variant || AWC odorant chemotaxis variant || memory retention defective || benzaldehyde chemotaxis variant || chemosensory response variant || chemotaxis variant || response to food variant || bromide chemotaxis defective || carbon dioxide avoidance variant |
| TPR-like | 0.02293 | INHERITED FROM: positive chemotaxis defective || associative learning variant || light body touch resistant || chemotaxis variant || dauer defective |
| "Winged helix" DNA-binding domain | 0.02839 | INHERITED FROM: anesthetic response variant || protein aggregation induced behavior variant || protein protein interaction variant || protein aggregation variant || germline transgene silencing variant || organism metabolism processing variant || paraquat hypersensitive || organism hypertonic lethality increased || protein expression increased || chemical hypersensitive || growth rate variant || spontaneous mutation rate increased || life span variant |
| PapD-like | 0.03487 | INHERITED FROM: lipid metabolism variant || developmental growth variant || dauer metabolism variant || fat content variant || larval growth variant || dauer lifespan variant || dauer lifespan extended || larval arrest || slow growth |
| WD40 repeat-like | 0.04502 | INHERITED FROM: protein aggregation induced behavior variant || osmotic avoidance variant || protein protein interaction variant || protein aggregation variant || late larval arrest || organism metabolism processing variant || antimicrobial gene expression variant || early larval arrest |
| ARM repeat | 0.04575 | INHERITED FROM: organism metabolism processing variant || RNAi response variant || gene expression variant || organism hypersensitive ionizing radiation || sick || protein expression variant |
| SH2 domain | 0.05021 | INHERITED FROM: aldicarb resistant || acetylcholinesterase inhibitor resistant || protein expression reduced || level of protein expression variant || protein expression variant |
| Homeodomain-like | 0.06893 | INHERITED FROM: carbon dioxide response variant || sexually dimorphic physiology variant || level of transgene expression variant || organism metabolism processing variant || adrenergic receptor antagonist response variant || egg laying imipramine resistant || growth rate variant || protein degradation variant || ectopic expression transgene || inhibitor of serotonin uptake variant || carbon dioxide avoidance variant || imipramine resistant |
| Acetyl-CoA synthetase-like | 0.07116 | INHERITED FROM: lipid metabolism variant |
| Calponin-homology domain, CH-domain | 0.07116 | INHERITED FROM: protein degradation variant |
| Cyclin-like | 0.07876 | INHERITED FROM: protein phosphorylation variant || protein phosphorylation reduced |
| CCCH zinc finger | 0.08711 | INHERITED FROM: transgene expression variant || organism metabolism processing variant || gene expression variant || ectopic expression transgene || mRNA expression ectopic |
| EGF/Laminin | 0.09564 | INHERITED FROM: octanol chemotaxis variant || negative chemotaxis variant || octanol chemotaxis defective || odorant negative chemotaxis defective |
| Translation proteins | 0.1067 | INHERITED FROM: transgene expression variant || protein protein interaction variant || protein aggregation variant || proteasome core activity variant || organism metabolism processing variant || protein phosphorylation variant || mRNA levels increased || protein phosphorylation increased || gene expression variant || sick |
| Galactose-binding domain-like | 0.114 | INHERITED FROM: protein interaction variant || protein protein interaction variant || protein aggregation variant |
| Ankyrin repeat | 0.1179 | INHERITED FROM: octanol chemotaxis variant || organism heat response variant || octanol chemotaxis defective || odorant negative chemotaxis defective || chemosensory response variant || chemotaxis variant |
| ABC transporter transmembrane region | 0.134 | INHERITED FROM: organism environmental stimulus response variant || RNAi response variant || cadmium response variant || colchicine hypersensitive || metal response variant |
| Nucleotide cyclase | 0.134 | INHERITED FROM: cation positive chemotaxis variant || organism environmental stimulus response variant || carbon dioxide response variant || osmotic avoidance variant || second messenger mediated signaling variant || lithium chemotaxis defective || diacetyl chemotaxis variant || bromide chemotaxis variant || iodide chemotaxis defective || positive chemotaxis variant || AWC odorant chemotaxis defective || alkaline pH chemotaxis variant || magnesium chemotaxis defective || iodide chemotaxis variant || anion positive chemotaxis defective || AWC odorant chemotaxis variant || cation positive chemotaxis defective || chemosensory response variant || chemotaxis variant || bromide chemotaxis defective |
| HLH, helix-loop-helix DNA-binding domain | 0.134 | INHERITED FROM: aqueous positive chemotaxis defective || aqueous positive chemotaxis variant || hypoxia response variant || organism metabolism processing variant || gene expression level reduced || lysine chemotaxis defective || ectopic expression transgene || RNA expression variant |
| RNI-like | 0.1415 | INHERITED FROM: resistant to protein aggregation induced paralysis |
| Calcium ATPase, transmembrane domain M | 0.1439 | INHERITED FROM: nicotine hypersensitive || organism environmental stimulus response variant || drug hypersensitive || lipid composition variant |
| Regulator of G-protein signaling, RGS | 0.1591 | INHERITED FROM: negative chemotaxis variant || mechanosensation variant || chemotaxis variant |
| Metal cation-transporting ATPase, ATP-binding domain N | 0.1591 | INHERITED FROM: nicotine hypersensitive || organism environmental stimulus response variant || drug hypersensitive || lipid composition variant |
| Calcium ATPase, transduction domain A | 0.1754 | INHERITED FROM: nicotine hypersensitive || organism environmental stimulus response variant || drug hypersensitive |
| Class II aaRS and biotin synthetases | 0.1754 | INHERITED FROM: organism environmental stimulus response variant || hypoxia resistant || hypoxia response variant || transgene expression variant || organism metabolism processing variant || gene expression variant || oxygen response variant |
| SH3-domain | 0.181 | INHERITED FROM: protein phosphorylation variant || aldicarb response variant || protein expression reduced || protein expression variant |
| E set domains | 0.1839 | INHERITED FROM: paraquat hypersensitive |
| Quinoprotein alcohol dehydrogenase-like | 0.1937 | INHERITED FROM: hypoxia response variant || L2 arrest || mRNA levels increased || protein metabolism variant || mid larval arrest || protein degradation variant || fat content increased |
| DBL homology domain (DH-domain) | 0.2138 | INHERITED FROM: organism environmental stimulus response variant || organism pathogen response variant || aldicarb response variant || bacterially unswollen || protein degradation variant || pathogen resistance increased |
| Multidrug efflux transporter AcrB transmembrane domain | 0.2148 | INHERITED FROM: positive chemotaxis defective || embryo osmotic integrity defective early emb || odorant positive chemotaxis defective || egg integrity defective early emb || odorant chemosensory response variant || chemotaxis variant |
| (Trans)glycosidases | 0.2577 | INHERITED FROM: pathogen susceptibility increased || pathogen load variant |
| Cytochrome P450 | 0.2577 | INHERITED FROM: cadmium response variant || metal response variant |
| Multidrug resistance efflux transporter EmrE | 0.2596 | INHERITED FROM: bacterially unswollen || pathogen resistance increased |
| BRCT domain | 0.2686 | INHERITED FROM: organism ionizing radiation response variant |
| 6-phosphogluconate dehydrogenase C-terminal domain-like | 0.2861 | INHERITED FROM: lipid metabolism variant || fat content variant |
| Bromodomain | 0.2861 | INHERITED FROM: organism UV hypersensitive || anesthetic response variant || drug adaptation variant || organism stress response variant || anesthetic resistant || ethanol resistant || acute functional tolerance to alcohol defective || sick || organism UV response variant |
| PLP-dependent transferases | 0.292 | INHERITED FROM: carbon dioxide response variant || carbon dioxide avoidance variant |
| Nucleotidylyl transferase | 0.3102 | INHERITED FROM: organism environmental stimulus response variant || paraquat resistant || hypoxia resistant || hypoxia response variant || organism metabolism processing variant || transgene expression increased || oxygen response variant |
| POZ domain | 0.3121 | INHERITED FROM: resistant to protein aggregation induced paralysis || protein aggregation induced behavior variant || L1 arrest || chemical hypersensitive || early larval arrest |
| SNARE-like | 0.3143 | INHERITED FROM: transgene expression variant || aldicarb resistant || organism metabolism processing variant || aldicarb response variant || pattern of transgene expression variant || transgene subcellular localization variant || acetylcholinesterase inhibitor resistant || protein metabolism variant || gene expression variant || acetylcholinesterase inhibitor response variant || sick |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0.3195 | INHERITED FROM: organism environmental stimulus response variant || nose touch variant || metabolic pathway variant || chemical response variant || RNAi response variant || antimicrobial gene expression variant || protein subcellular localization variant || drug induced gene expression variant || aging variant || drug resistant || growth rate variant || protein expression variant |
| Cysteine proteinases | 0.3209 | INHERITED FROM: protein interaction variant || protein protein interaction variant || organism metabolism processing variant || pattern of transgene expression variant || paraquat hypersensitive || hypoosmotic shock hypersensitive || osmotic integrity variant |
| RNA-binding domain, RBD | 0.3244 | INHERITED FROM: maintenance of gene silencing variant || organism metabolism processing variant || mRNA export variant || antimicrobial gene expression variant || no induction of antimicrobial peptide expression after infection || starvation induced apoptosis variant || innate immune response variant || alternative splicing variant || sick || RNA expression variant || RNA processing variant |
| Ribosomal protein S5 domain 2-like | 0.3295 | INHERITED FROM: transgene expression variant || early larval arrest |
| SAM/Pointed domain | 0.3332 | INHERITED FROM: aldicarb response variant |
| Lipocalins | 0.3332 | INHERITED FROM: lipid metabolism variant || fat content variant || paraquat hypersensitive || fat content increased |
| Growth factor receptor domain | 0.3573 | INHERITED FROM: protein degradation variant |
| Cation efflux protein transmembrane domain-like | 0.3807 | INHERITED FROM: manganese toxicity resistant || cadmium hypersensitive || metal response variant || manganese response variant |
| Translation proteins SH3-like domain | 0.3807 | INHERITED FROM: transgene expression variant || protein protein interaction variant || protein aggregation variant || organism metabolism processing variant || gene expression variant || early larval arrest |
| Acid proteases | 0.4103 | INHERITED FROM: protein interaction variant || transgene expression variant || protein protein interaction variant || protein aggregation variant || organism metabolism processing variant || pattern of transgene expression variant || transgene subcellular localization variant || hypoosmotic shock hypersensitive || gene expression variant || osmotic integrity variant |
| Tropomyosin | 0.4174 | INHERITED FROM: drug resistant |
| Nicotinic receptor ligand binding domain-like | 0.4315 | INHERITED FROM: nicotine resistant || organism environmental stimulus response variant || selenium response variant || aqueous chemosensory response variant || sodium chloride chemotaxis variant || chemical response variant || drug response variant || hypoosmotic shock hypersensitive || mechanosensation variant || antihelmintic response variant || DMPP response variant || cholinergic agonist resistant |
| Ubiquitin-like | 0.4419 | INHERITED FROM: heteroplasmy || protein interaction variant || protein protein interaction variant || protein aggregation variant || organism metabolism processing variant |
| FYVE/PHD zinc finger | 0.4432 | INHERITED FROM: organism UV hypersensitive || protein modification variant || protein methylation variant || ectopic expression transgene || organism UV response variant |
| Cysteine-rich domain | 0.4611 | INHERITED FROM: odorant positive chemotaxis variant || organism metabolism processing variant || organism pathogen response variant || aldicarb response variant || transgene subcellular localization variant || antimicrobial gene expression variant || positive chemotaxis variant || bacterially unswollen || protein subcellular localization variant || drug induced gene expression variant || organism oxidative stress resistant || odorant chemosensory response variant || chemotaxis variant |
| HAD-like | 0.4625 | INHERITED FROM: nicotine hypersensitive |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.468 | INHERITED FROM: nicotine resistant || organism environmental stimulus response variant || selenium response variant || aqueous chemosensory response variant || sodium chloride chemotaxis variant || chemical response variant || drug response variant || positive chemotaxis variant || hypoosmotic shock hypersensitive || mechanosensation variant || antihelmintic response variant || DMPP response variant || protein degradation variant || cholinergic agonist resistant |
| UDP-Glycosyltransferase/glycogen phosphorylase | 0.4833 | INHERITED FROM: organism osmotic stress response variant |
| DHS-like NAD/FAD-binding domain | 0.5023 | INHERITED FROM: protein modification variant || protein acetylation variant || life span variant |
| PRTase-like | 0.5023 | INHERITED FROM: drug resistant || Fluorouracil resistant |
| Myosin rod fragments | 0.5023 | INHERITED FROM: drug resistant |
| Riboflavin synthase domain-like | 0.5504 | INHERITED FROM: pattern protein expression variant |
| Calpain large subunit, middle domain (domain III) | 0.5504 | INHERITED FROM: metabolic pathway variant || protein metabolism variant || protein degradation variant |
| Ferredoxin reductase-like, C-terminal NADP-linked domain | 0.5504 | INHERITED FROM: pattern protein expression variant |
| FAD-linked reductases, C-terminal domain | 0.5626 | INHERITED FROM: life span variant |
| Cystine-knot cytokines | 0.5626 | INHERITED FROM: levamisole response variant || nicotine response variant |
| WW domain | 0.5626 | INHERITED FROM: maintenance of gene silencing variant || aldicarb resistant || acetylcholinesterase inhibitor resistant |
| Sm-like ribonucleoproteins | 0.5626 | INHERITED FROM: unfolded protein response variant || transgene expression variant || organism heat response variant || pattern of transgene expression variant || protein subcellular localization variant || gene expression variant || sick || life span variant |
| GTPase activation domain, GAP | 0.5648 | INHERITED FROM: protein expression variant |
| Voltage-gated potassium channels | 0.5966 | INHERITED FROM: positive chemotaxis defective || serotonin response variant || metabolic pathway variant || adrenergic receptor antagonist response variant || mechanosensation variant || protein metabolism variant || growth rate variant || protein degradation variant |
| Seven-hairpin glycosidases | 0.5997 | INHERITED FROM: protein protein interaction variant || protein aggregation variant || extended life span |
| FAD/NAD(P)-binding domain | 0.6016 | INHERITED FROM: pesticide response variant || ATP levels variant || ATP levels reduced || life span variant |
| SET domain | 0.6081 | INHERITED FROM: protein modification variant || maintenance of gene silencing variant || protein methylation variant || RNAi response variant || shortened life span || dosage compensation variant || somatic transgene silencing variant || histone methylation variant || ectopic expression antibody || spontaneous mutation rate increased || life span variant || protein expression variant |
| UBC-like | 0.6326 | INHERITED FROM: protein interaction variant || protein protein interaction variant || protein aggregation variant || late larval arrest || organism metabolism processing variant || pattern of transgene expression variant || transgene subcellular localization variant || gene expression variant || sick |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0.657 | INHERITED FROM: organism environmental stimulus response variant || pathogen susceptibility increased || organism pathogen response variant || transgene subcellular localization variant || life span variant |
| Lipovitellin-phosvitin complex, superhelical domain | 0.657 | INHERITED FROM: organism environmental stimulus response variant || pathogen susceptibility increased || organism pathogen response variant || transgene subcellular localization variant || life span variant |
| KA1-like | 0.657 | INHERITED FROM: RNA expression variant |
| Osmotin, thaumatin-like protein | 0.657 | INHERITED FROM: cadmium response variant || cadmium hypersensitive || metal response variant || transgene expression reduced |
| Nucleotide-binding domain | 0.657 | INHERITED FROM: extended life span || life span variant |
| MFS general substrate transporter | 0.6655 | INHERITED FROM: organism high sodium chloride hypersensitive |
| Clavaminate synthase-like | 0.7047 | INHERITED FROM: organism temperature response variant || life span variant |
| 4Fe-4S ferredoxins | 0.7189 | INHERITED FROM: extended life span |
| S15/NS1 RNA-binding domain | 0.7189 | INHERITED FROM: transgene expression increased |
| Frizzled cysteine-rich domain | 0.7189 | INHERITED FROM: antibody staining variant || transgene expression reduced |
| GST C-terminal domain-like | 0.7464 | INHERITED FROM: organism electrophilic stress hypersensitive || organism environmental stimulus response variant || organism stress response variant || cadmium response variant || cadmium hypersensitive || enzyme activity variant || enzyme activity reduced || organism heat hypersensitive |
| PAZ domain | 0.7808 | INHERITED FROM: 21U RNA expression variant || maintenance of gene silencing variant || RNAi response variant || mRNA levels increased || RNAi enhanced || siRNA expression variant || somatic transgene silencing variant || RNA expression variant |
| Ribonuclease H-like | 0.7853 | INHERITED FROM: 21U RNA expression variant || maintenance of gene silencing variant || RNAi response variant || RNAi enhanced || siRNA expression variant || somatic transgene silencing variant || RNA expression variant |
| MIT domain | 0.7859 | INHERITED FROM: protein interaction variant || protein protein interaction variant || protein aggregation variant |
| ADC-like | 0.7859 | INHERITED FROM: protein interaction variant || metabolic pathway variant || protein protein interaction variant || protein aggregation variant || level of transgene expression variant || protein metabolism variant |
| Glucocorticoid receptor-like (DNA-binding domain) | 0.7859 | INHERITED FROM: gene expression level high || level of transgene expression variant || gene expression level reduced || SDS sensitive dauer || fat content increased || dauer resistance to harsh conditions variant || transgene expression reduced |
| alpha/beta-Hydrolases | 0.7959 | INHERITED FROM: acetylcholinesterase activity variant || acetylcholinesterase reduced |
| Fibronectin type III | 0.8454 | INHERITED FROM: growth rate variant || protein degradation variant |
| Leucine zipper domain | 0.8868 | INHERITED FROM: pore forming toxin response variant || pathogen susceptibility increased || level of transgene expression variant || mRNA levels reduced || mRNA expression variant || transgene expression reduced |
| UBA-like | 0.8977 | INHERITED FROM: protein protein interaction variant || protein aggregation variant |
| EF-hand | 0.9104 | INHERITED FROM: protein interaction variant || protein aggregation variant |
| beta-beta-alpha zinc fingers | 0.938 | INHERITED FROM: organism metabolism processing variant || egg laying imipramine resistant || inhibitor of serotonin uptake variant || imipramine resistant || egg laying serotonin resistant |
| DNA/RNA polymerases | 0.9541 | INHERITED FROM: DNA repair variant || DNA metabolism variant |
| p53-like transcription factors | 0.9634 | INHERITED FROM: level of transgene expression variant || gene expression level reduced || ectopic expression transgene |
| Ribonuclease PH domain 2-like | 0.965 | INHERITED FROM: early larval arrest |
| Immunoglobulin | 0.99 | INHERITED FROM: aldicarb response variant || growth rate variant || protein degradation variant |
| Thioredoxin-like | 0.9993 | INHERITED FROM: organism electrophilic stress hypersensitive || organism environmental stimulus response variant || paraquat response variant || organism stress response variant || cadmium hypersensitive || enzyme activity variant || enzyme activity reduced || organism heat hypersensitive |
| RING/U-box | 1 | INHERITED FROM: protein interaction variant || transgene expression variant || protein protein interaction variant || protein aggregation variant || organism metabolism processing variant || pattern of transgene expression variant || transgene subcellular localization variant || gene expression variant |
| CoA-dependent acyltransferases | 1 | INHERITED FROM: fat content variant |
| Saposin | 1 | INHERITED FROM: transgene expression variant || level of transgene expression variant || pathogen load variant || increased pathogen survival || transgene expression reduced |
| F-box domain | 1 | INHERITED FROM: resistant to protein aggregation induced paralysis |
| FKBP-like | 1 | INHERITED FROM: protein interaction variant || protein protein interaction variant || protein aggregation variant || pattern of transgene expression variant || transgene subcellular localization variant |
| Nuclear receptor ligand-binding domain | 1 | INHERITED FROM: gene expression level high || lipid metabolism variant || level of transgene expression variant || gene expression level reduced || SDS sensitive dauer || fat content increased || dauer resistance to harsh conditions variant || transgene expression reduced |
| Eukaryotic type KH-domain (KH-domain type I) | 1 | INHERITED FROM: RNA expression variant |
| Bet v1-like | 1 | INHERITED FROM: growth rate variant |
| Family A G protein-coupled receptor-like | 1 | INHERITED FROM: serotonin induced fat reduction variant || locomotion rate serotonin variant || male tail curling serotonin variant || serotonin induced pumping variant |
| B-box zinc-binding domain | 1 | INHERITED FROM: protein interaction variant || transgene expression variant || protein protein interaction variant || protein aggregation variant || organism metabolism processing variant || transgene subcellular localization variant || gene expression variant |
| Ligand-binding domain in the NO signalling and Golgi transport | 1 | INHERITED FROM: carbon dioxide response variant || carbon dioxide avoidance variant |
| Cyclophilin-like | 1 | INHERITED FROM: protein interaction variant || transgene expression variant || protein protein interaction variant || protein aggregation variant || pattern of transgene expression variant || transgene subcellular localization variant || gene expression variant |
| Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
| Elafin-like | 0 | Direct |
| Carbohydrate phosphatase | 0 | Direct |
| ArfGap/RecO-like zinc finger | 0 | Direct |
| Nucleoporin domain | 0 | Direct |
| ClpP/crotonase | 0 | Direct |
| MOSC N-terminal domain-like | 0 | Direct |
| PP2C-like | 0 | Direct |
| Band 7/SPFH domain | 0 | Direct |
| GAT-like domain | 0 | Direct |
| Bacterial exopeptidase dimerisation domain | 0 | Direct |
| Aquaporin-like | 0 | Direct |
| PreATP-grasp domain | 0 | Direct |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| 3-carboxy-cis,cis-mucoante lactonizing enzyme | 0 | Direct |
| Profilin (actin-binding protein) | 0 | Direct |
| Hect, E3 ligase catalytic domain | 0 | Direct |
| TGS-like | 0 | Direct |
| Troponin coil-coiled subunits | 0 | Direct |
| Tricorn protease domain 2 | 0 | Direct |
| Thiamin diphosphate-binding fold (THDP-binding) | 0 | Direct |
| Purine and uridine phosphorylases | 0 | Direct |
| DNA repair protein MutS, domain III | 0 | Direct |
| Protease propeptides/inhibitors | 0 | Direct |
| Nucleoside diphosphate kinase, NDK | 0 | Direct |
| DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
| Phosphoglucomutase, C-terminal domain | 0 | Direct |
| Aminoacid dehydrogenase-like, N-terminal domain | 0 | Direct |
| CO dehydrogenase ISP C-domain like | 0 | Direct |
| Ribosomal proteins S24e, L23 and L15e | 0 | Direct |
| Mitochondrial carrier | 0 | Direct |
| Intermediate filament protein, coiled coil region | 0 | Direct |
| Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
| Citrate synthase | 0 | Direct |
| PLP-binding barrel | 0 | Direct |
| HSP20-like chaperones | 0 | Direct |
| Class I glutamine amidotransferase-like | 0 | Direct |
| Lamin A/C globular tail domain | 0 | Direct |
| Subtilisin-like | 0 | Direct |
| Ran binding protein zinc finger-like | 0 | Direct |
| Heme-dependent peroxidases | 0 | Direct |
| Arginase/deacetylase | 0 | Direct |
| Tim10-like | 0 | Direct |
| YbiA-like | 0 | Direct |
| Molybdenum cofactor-binding domain | 0 | Direct |
| WGR domain-like | 0 | Direct |
| Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | Direct |
| Creatinase/prolidase N-terminal domain | 0 | Direct |
| ADP-ribosylation | 0 | Direct |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0 | Direct |
| Galactose oxidase, central domain | 0 | Direct |
| Sec63 N-terminal domain-like | 0 | Direct |
| Integrin domains | 0 | Direct |
| Ribosomal protein L1 | 0 | Direct |
| PUA domain-like | 0 | Direct |
| Acyl-CoA dehydrogenase NM domain-like | 0 | Direct |
| Pepsin inhibitor-3 | 0 | Direct |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
| Cadherin-like | 0 | Direct |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | Direct |
| F1F0 ATP synthase subunit C | 0 | Direct |
| Radical SAM enzymes | 0 | Direct |
| Sec1/munc18-like (SM) proteins | 0 | Direct |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| PIN domain-like | 0 | Direct |
| MIR domain | 0 | Direct |
| Thiolase-like | 0 | Direct |
| FF domain | 0 | Direct |
| Proton glutamate symport protein | 0 | Direct |
| Glycolipid transfer protein, GLTP | 0 | Direct |
| Isocitrate/Isopropylmalate dehydrogenase-like | 0 | Direct |
| Second domain of FERM | 0 | Direct |
| dsRNA-binding domain-like | 0 | Direct |
| PABC (PABP) domain | 0 | Direct |
| Insulin-like | 0 | Direct |
| Ribosomal protein L10-like | 0 | Direct |
| Fibrinogen C-terminal domain-like | 0 | Direct |
| Translational machinery components | 0 | Direct |
| Terpenoid cyclases/Protein prenyltransferases | 0 | Direct |
| Phosphoenolpyruvate/pyruvate domain | 0 | Direct |
| PK beta-barrel domain-like | 0 | Direct |
| Alpha-L RNA-binding motif | 0 | Direct |
| Clc chloride channel | 0 | Direct |
| Cation efflux protein cytoplasmic domain-like | 0 | Direct |
| ARID-like | 0 | Direct |
| PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | Direct |
| Blood coagulation inhibitor (disintegrin) | 0 | Direct |
| PEP carboxykinase N-terminal domain | 0 | Direct |
| GroEL equatorial domain-like | 0 | Direct |
| L-aspartase-like | 0 | Direct |
| LysM domain | 0 | Direct |
| SCP-like | 0 | Direct |
| Succinyl-CoA synthetase domains | 0 | Direct |
| Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | Direct |
| FtsH protease domain-like | 0 | Direct |
| SIS domain | 0 | Direct |
| eIF4e-like | 0 | Direct |
| DEATH domain | 0 | Direct |
| Chaperone J-domain | 0 | Direct |
| Sec7 domain | 0 | Direct |
| t-snare proteins | 0 | Direct |
| Terpenoid synthases | 0 | Direct |
| Rap/Ran-GAP | 0 | Direct |
| Clathrin adaptor appendage domain | 0 | Direct |
| Zn-binding ribosomal proteins | 0 | Direct |
| Oxysterol-binding protein-like | 0 | Direct |
| Galactose mutarotase-like | 0 | Direct |
| BEACH domain | 0 | Direct |
| JAB1/MPN domain | 0 | Direct |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | Direct |
| 2Fe-2S ferredoxin-like | 0 | Direct |
| Class II aaRS ABD-related | 0 | Direct |
| RBP11-like subunits of RNA polymerase | 0 | Direct |
| SAICAR synthase-like | 0 | Direct |
| Nop domain | 0 | Direct |
| Cdc48 domain 2-like | 0 | Direct |
| CRAL/TRIO N-terminal domain | 0 | Direct |
| Cullin repeat-like | 0 | Direct |
| Hormone receptor domain | 0 | Direct |
| Putative DNA-binding domain | 0 | Direct |
| Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0 | Direct |
| Helical domain of Sec23/24 | 0 | Direct |
| Restriction endonuclease-like | 0 | Direct |
| Ribulose-phoshate binding barrel | 0 | Direct |
| GAS2 domain-like | 0 | Direct |
| Skp1 dimerisation domain-like | 0 | Direct |
| Doublecortin (DC) | 0 | Direct |
| PYP-like sensor domain (PAS domain) | 0 | Direct |
| Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | Direct |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
| PEP carboxykinase-like | 0 | Direct |
| Cytochrome c | 0 | Direct |
| Spectrin repeat | 0 | Direct |
| alpha-catenin/vinculin-like | 0 | Direct |
| GINS helical bundle-like | 0 | Direct |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
| R3H domain | 0 | Direct |
| Hypothetical protein c14orf129, hspc210 | 0 | Direct |
| TK C-terminal domain-like | 0 | Direct |
| CAD & PB1 domains | 0 | Direct |
| GYF domain | 0 | Direct |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
| Actin-like ATPase domain | 0 | Direct |
| Subdomain of clathrin and coatomer appendage domain | 0 | Direct |
| AN1-like Zinc finger | 0 | Direct |
| PEBP-like | 0 | Direct |
| Aldolase | 0 | Direct |
| Cullin homology domain | 0 | Direct |
| WWE domain | 0 | Direct |
| Domain of poly(ADP-ribose) polymerase | 0 | Direct |
| Zn-finger domain of Sec23/24 | 0 | Direct |
| Chitinase insertion domain | 0 | Direct |
| Complement control module/SCR domain | 0 | Direct |
| DNA ligase/mRNA capping enzyme, catalytic domain | 0 | Direct |
| ALDH-like | 0 | Direct |
| L30e-like | 0 | Direct |
| SAND domain-like | 0 | Direct |
| Nucleotidyltransferase | 0 | Direct |
| CO dehydrogenase molybdoprotein N-domain-like | 0 | Direct |
| ThrRS/AlaRS common domain | 0 | Direct |
| CBD9-like | 0 | Direct |
| Phosphoglucomutase, first 3 domains | 0 | Direct |
| PHM/PNGase F | 0 | Direct |
| GroEL-intermediate domain like | 0 | Direct |
| Acid phosphatase/Vanadium-dependent haloperoxidase | 0 | Direct |
| Annexin | 0 | Direct |
| ISP domain | 0 | Direct |
| HSP90 C-terminal domain | 0 | Direct |
| Invertebrate chitin-binding proteins | 0 | Direct |
| SPOC domain-like | 0 | Direct |
| Carbon-nitrogen hydrolase | 0 | Direct |
| Activating enzymes of the ubiquitin-like proteins | 0 | Direct |
| Ferritin-like | 0 | Direct |
| Cu,Zn superoxide dismutase-like | 0 | Direct |
| Type II DNA topoisomerase | 0 | Direct |
| PGBD-like | 0 | Direct |
| ValRS/IleRS/LeuRS editing domain | 0 | Direct |
| Ribokinase-like | 0 | Direct |
| Integrin alpha N-terminal domain | 0 | Direct |
| PLC-like phosphodiesterases | 0 | Direct |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | Direct |
| Glutathione synthetase ATP-binding domain-like | 0 | Direct |
| Smc hinge domain | 0 | Direct |
| Formate/glycerate dehydrogenase catalytic domain-like | 0 | Direct |
| SWIB/MDM2 domain | 0 | Direct |
| alpha/beta knot | 0 | Direct |
| Composite domain of metallo-dependent hydrolases | 0 | Direct |
| GHMP Kinase, C-terminal domain | 0 | Direct |
| 14-3-3 protein | 0 | Direct |
| MgtE membrane domain-like | 0 | Direct |
| Ribosomal L27 protein-like | 0 | Direct |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
| FAD-dependent thiol oxidase | 0 | Direct |
| Heme-dependent catalase-like | 0 | Direct |
| SMAD MH1 domain | 0 | Direct |
| Transducin (heterotrimeric G protein), gamma chain | 0 | Direct |
| HMG-box | 0 | Direct |
| ENTH/VHS domain | 0 | Direct |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
| Surp module (SWAP domain) | 0 | Direct |
| Hedgehog/intein (Hint) domain | 0 | Direct |
| Rudiment single hybrid motif | 0 | Direct |
| PurM C-terminal domain-like | 0 | Direct |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
| Single hybrid motif | 0 | Direct |
| SMAD/FHA domain | 0 | Direct |
| Thyroglobulin type-1 domain | 0 | Direct |
| Tubulin nucleotide-binding domain-like | 0 | Direct |
| Families 57/38 glycoside transferase middle domain | 0 | Direct |
| Polo-box domain | 0 | Direct |
| VPS9 domain | 0 | Direct |
| Chromo domain-like | 0 | Direct |
| GroEL apical domain-like | 0 | Direct |
| Tubulin C-terminal domain-like | 0 | Direct |
| lambda repressor-like DNA-binding domains | 0 | Direct |
| Carboxypeptidase regulatory domain-like | 0 | Direct |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | Direct |
| Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | Direct |
| Periplasmic binding protein-like II | 0 | Direct |
| cAMP-binding domain-like | 0 | Direct |
| S-adenosylmethionine synthetase | 0 | Direct |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | Direct |
| Kringle-like | 0 | Direct |
| LEM domain | 0 | Direct |
| YWTD domain | 0 | Direct |
| LDH C-terminal domain-like | 0 | Direct |
| GroES-like | 0 | Direct |
| Small-conductance potassium channel | 0 | Direct |
| Outer arm dynein light chain 1 | 0 | Direct |
| Calcium-dependent phosphotriesterase | 0 | Direct |
| beta-lactamase/transpeptidase-like | 0 | Direct |
| Carbonic anhydrase | 0 | Direct |
| Cystatin/monellin | 0 | Direct |
| Diaminopimelate epimerase-like | 0 | Direct |
| PurM N-terminal domain-like | 0 | Direct |
| HSP40/DnaJ peptide-binding domain | 0 | Direct |
| PAP/OAS1 substrate-binding domain | 0 | Direct |
| Tubby C-terminal domain-like | 0 | Direct |
| Pentein | 0 | Direct |
| Transducin (alpha subunit), insertion domain | 0 | Direct |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | Direct |
| HCP-like | 0 | Direct |
| MFPT repeat-like | 0 | Direct |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
| P-loop containing nucleoside triphosphate hydrolases | 0.0000002175 | Direct |
| PH domain-like | 0.00007823 | Direct |
| Histone-fold | 0.0001604 | Direct |
| Protein kinase-like (PK-like) | 0.008435 | Inherited |
| PDZ domain-like | 0.01288 | Inherited |
| Nucleic acid-binding proteins | 0.02027 | Inherited |
| Periplasmic binding protein-like I | 0.02075 | Inherited |
| TPR-like | 0.02293 | Inherited |
| "Winged helix" DNA-binding domain | 0.02839 | Inherited |
| PapD-like | 0.03487 | Inherited |
| WD40 repeat-like | 0.04502 | Inherited |
| ARM repeat | 0.04575 | Inherited |
| SH2 domain | 0.05021 | Inherited |
| Homeodomain-like | 0.06893 | Inherited |
| Acetyl-CoA synthetase-like | 0.07116 | Inherited |
| Calponin-homology domain, CH-domain | 0.07116 | Inherited |
| Cyclin-like | 0.07876 | Inherited |
| CCCH zinc finger | 0.08711 | Inherited |
| EGF/Laminin | 0.09564 | Inherited |
| Translation proteins | 0.1067 | Inherited |
| Galactose-binding domain-like | 0.114 | Inherited |
| Ankyrin repeat | 0.1179 | Inherited |
| ABC transporter transmembrane region | 0.134 | Inherited |
| Nucleotide cyclase | 0.134 | Inherited |
| HLH, helix-loop-helix DNA-binding domain | 0.134 | Inherited |
| RNI-like | 0.1415 | Inherited |
| Calcium ATPase, transmembrane domain M | 0.1439 | Inherited |
| Regulator of G-protein signaling, RGS | 0.1591 | Inherited |
| Metal cation-transporting ATPase, ATP-binding domain N | 0.1591 | Inherited |
| Calcium ATPase, transduction domain A | 0.1754 | Inherited |
| Class II aaRS and biotin synthetases | 0.1754 | Inherited |
| SH3-domain | 0.181 | Inherited |
| E set domains | 0.1839 | Inherited |
| Quinoprotein alcohol dehydrogenase-like | 0.1937 | Inherited |
| DBL homology domain (DH-domain) | 0.2138 | Inherited |
| Multidrug efflux transporter AcrB transmembrane domain | 0.2148 | Inherited |
| (Trans)glycosidases | 0.2577 | Inherited |
| Cytochrome P450 | 0.2577 | Inherited |
| Multidrug resistance efflux transporter EmrE | 0.2596 | Inherited |
| BRCT domain | 0.2686 | Inherited |
| 6-phosphogluconate dehydrogenase C-terminal domain-like | 0.2861 | Inherited |
| Bromodomain | 0.2861 | Inherited |
| PLP-dependent transferases | 0.292 | Inherited |
| Nucleotidylyl transferase | 0.3102 | Inherited |
| POZ domain | 0.3121 | Inherited |
| SNARE-like | 0.3143 | Inherited |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0.3195 | Inherited |
| Cysteine proteinases | 0.3209 | Inherited |
| RNA-binding domain, RBD | 0.3244 | Inherited |
| Ribosomal protein S5 domain 2-like | 0.3295 | Inherited |
| SAM/Pointed domain | 0.3332 | Inherited |
| Lipocalins | 0.3332 | Inherited |
| Growth factor receptor domain | 0.3573 | Inherited |
| Cation efflux protein transmembrane domain-like | 0.3807 | Inherited |
| Translation proteins SH3-like domain | 0.3807 | Inherited |
| Acid proteases | 0.4103 | Inherited |
| Tropomyosin | 0.4174 | Inherited |
| Nicotinic receptor ligand binding domain-like | 0.4315 | Inherited |
| Ubiquitin-like | 0.4419 | Inherited |
| FYVE/PHD zinc finger | 0.4432 | Inherited |
| Cysteine-rich domain | 0.4611 | Inherited |
| HAD-like | 0.4625 | Inherited |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.468 | Inherited |
| UDP-Glycosyltransferase/glycogen phosphorylase | 0.4833 | Inherited |
| DHS-like NAD/FAD-binding domain | 0.5023 | Inherited |
| PRTase-like | 0.5023 | Inherited |
| Myosin rod fragments | 0.5023 | Inherited |
| Riboflavin synthase domain-like | 0.5504 | Inherited |
| Calpain large subunit, middle domain (domain III) | 0.5504 | Inherited |
| Ferredoxin reductase-like, C-terminal NADP-linked domain | 0.5504 | Inherited |
| FAD-linked reductases, C-terminal domain | 0.5626 | Inherited |
| Cystine-knot cytokines | 0.5626 | Inherited |
| WW domain | 0.5626 | Inherited |
| Sm-like ribonucleoproteins | 0.5626 | Inherited |
| GTPase activation domain, GAP | 0.5648 | Inherited |
| Voltage-gated potassium channels | 0.5966 | Inherited |
| Seven-hairpin glycosidases | 0.5997 | Inherited |
| FAD/NAD(P)-binding domain | 0.6016 | Inherited |
| SET domain | 0.6081 | Inherited |
| UBC-like | 0.6326 | Inherited |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0.657 | Inherited |
| Lipovitellin-phosvitin complex, superhelical domain | 0.657 | Inherited |
| KA1-like | 0.657 | Inherited |
| Osmotin, thaumatin-like protein | 0.657 | Inherited |
| Nucleotide-binding domain | 0.657 | Inherited |
| MFS general substrate transporter | 0.6655 | Inherited |
| Clavaminate synthase-like | 0.7047 | Inherited |
| 4Fe-4S ferredoxins | 0.7189 | Inherited |
| S15/NS1 RNA-binding domain | 0.7189 | Inherited |
| Frizzled cysteine-rich domain | 0.7189 | Inherited |
| GST C-terminal domain-like | 0.7464 | Inherited |
| PAZ domain | 0.7808 | Inherited |
| Ribonuclease H-like | 0.7853 | Inherited |
| MIT domain | 0.7859 | Inherited |
| ADC-like | 0.7859 | Inherited |
| Glucocorticoid receptor-like (DNA-binding domain) | 0.7859 | Inherited |
| alpha/beta-Hydrolases | 0.7959 | Inherited |
| Fibronectin type III | 0.8454 | Inherited |
| Leucine zipper domain | 0.8868 | Inherited |
| UBA-like | 0.8977 | Inherited |
| EF-hand | 0.9104 | Inherited |
| beta-beta-alpha zinc fingers | 0.938 | Inherited |
| DNA/RNA polymerases | 0.9541 | Inherited |
| p53-like transcription factors | 0.9634 | Inherited |
| Ribonuclease PH domain 2-like | 0.965 | Inherited |
| Immunoglobulin | 0.99 | Inherited |
| Thioredoxin-like | 0.9993 | Inherited |
| RING/U-box | 1 | Inherited |
| CoA-dependent acyltransferases | 1 | Inherited |
| Saposin | 1 | Inherited |
| F-box domain | 1 | Inherited |
| FKBP-like | 1 | Inherited |
| Nuclear receptor ligand-binding domain | 1 | Inherited |
| Eukaryotic type KH-domain (KH-domain type I) | 1 | Inherited |
| Bet v1-like | 1 | Inherited |
| Family A G protein-coupled receptor-like | 1 | Inherited |
| B-box zinc-binding domain | 1 | Inherited |
| Ligand-binding domain in the NO signalling and Golgi transport | 1 | Inherited |
| Cyclophilin-like | 1 | Inherited |
(show details)
Supra-domains annotated to this WP term (Not in SPWP)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
55729,55729
55729 - Acyl-CoA N-acyltransferases (Nat)
55729 - Acyl-CoA N-acyltransferases (Nat) | 0 | DIRECT |
81324,53850
81324 - Voltage-gated potassium channels
53850 - Periplasmic binding protein-like II | 0 | DIRECT |
53474,53474
53474 - alpha/beta-Hydrolases
53474 - alpha/beta-Hydrolases | 0 | DIRECT |
53738,55957
53738 - Phosphoglucomutase, first 3 domains
55957 - Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
52047,52047
52047 - RNI-like
52047 - RNI-like | 0 | DIRECT |
90229,90229
90229 - CCCH zinc finger
90229 - CCCH zinc finger | 0 | DIRECT |
57889,57889
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0 | DIRECT |
88713,88688
88713 - Glycoside hydrolase/deacetylase
88688 - Families 57/38 glycoside transferase middle domain | 0 | DIRECT |
52490,55307
52490 - Tubulin nucleotide-binding domain-like
55307 - Tubulin C-terminal domain-like | 0 | DIRECT |
51338,51556
51338 - Composite domain of metallo-dependent hydrolases
51556 - Metallo-dependent hydrolases | 0 | DIRECT |
50249,50249
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
50156,50044
50156 - PDZ domain-like
50044 - SH3-domain | 0 | DIRECT |
82895,82895
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat | 0 | DIRECT |
57184,57184
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | DIRECT |
57196,57184
57196 - EGF/Laminin
57184 - Growth factor receptor domain | 0 | DIRECT |
52540,47917
52540 - P-loop containing nucleoside triphosphate hydrolases
47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
47741,56176
47741 - CO dehydrogenase ISP C-domain like
56176 - FAD-binding/transporter-associated domain-like | 0 | DIRECT |
74650,51445
74650 - Galactose mutarotase-like
51445 - (Trans)glycosidases | 0 | DIRECT |
51905,55424
51905 - FAD/NAD(P)-binding domain
55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | DIRECT |
51971,54373
51971 - Nucleotide-binding domain
54373 - FAD-linked reductases, C-terminal domain | 0 | DIRECT |
82919,53300
82919 - Zn-finger domain of Sec23/24
53300 - vWA-like | 0 | DIRECT |
47473,51695
47473 - EF-hand
51695 - PLC-like phosphodiesterases | 0 | DIRECT |
56601,48403
56601 - beta-lactamase/transpeptidase-like
48403 - Ankyrin repeat | 0 | DIRECT |
50044,50044
50044 - SH3-domain
50044 - SH3-domain | 0 | DIRECT |
50044,52540
50044 - SH3-domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
81301,81631
81301 - Nucleotidyltransferase
81631 - PAP/OAS1 substrate-binding domain | 0 | DIRECT |
52113,52113
52113 - BRCT domain
52113 - BRCT domain | 0 | DIRECT |
47954,47954
47954 - Cyclin-like
47954 - Cyclin-like | 0 | DIRECT |
81383,50978
81383 - F-box domain
50978 - WD40 repeat-like | 0 | DIRECT |
54534,54534
54534 - FKBP-like
54534 - FKBP-like | 0 | DIRECT |
57196,63825
57196 - EGF/Laminin
63825 - YWTD domain | 0 | DIRECT |
56645,47203
56645 - Acyl-CoA dehydrogenase NM domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
57756,50630
57756 - Retrovirus zinc finger-like domains
50630 - Acid proteases | 0 | DIRECT |
50129,51735
50129 - GroES-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
141673,50800
141673 - MOSC N-terminal domain-like
50800 - PK beta-barrel domain-like | 0 | DIRECT |
57362,57362
57362 - BPTI-like
57362 - BPTI-like | 0 | DIRECT |
56112,82615
56112 - Protein kinase-like (PK-like)
82615 - Polo-box domain | 0 | DIRECT |
47576,47576
47576 - Calponin-homology domain, CH-domain
47576 - Calponin-homology domain, CH-domain | 0 | DIRECT |
50729,56112
50729 - PH domain-like
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
52518,52922
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52922 - TK C-terminal domain-like | 0 | DIRECT |
161093,161093
161093 - MgtE membrane domain-like
161093 - MgtE membrane domain-like | 0 | DIRECT |
81333,81333
81333 - F1F0 ATP synthase subunit C
81333 - F1F0 ATP synthase subunit C | 0 | DIRECT |
101690,53098
101690 - PAZ domain
53098 - Ribonuclease H-like | 0 | DIRECT |
47473,103506
47473 - EF-hand
103506 - Mitochondrial carrier | 0 | DIRECT |
51695,49562
51695 - PLC-like phosphodiesterases
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
54768,54768
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like | 0 | DIRECT |
54160,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
50978,50998
50978 - WD40 repeat-like
50998 - Quinoprotein alcohol dehydrogenase-like | 0 | DIRECT |
52540,46785
52540 - P-loop containing nucleoside triphosphate hydrolases
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
56059,52210
56059 - Glutathione synthetase ATP-binding domain-like
52210 - Succinyl-CoA synthetase domains | 0 | DIRECT |
103473,103473
103473 - MFS general substrate transporter
103473 - MFS general substrate transporter | 0 | DIRECT |
50692,54585
50692 - ADC-like
54585 - Cdc48 domain 2-like | 0 | DIRECT |
53187,49464
53187 - Zn-dependent exopeptidases
49464 - Carboxypeptidase regulatory domain-like | 0 | DIRECT |
57903,82199
57903 - FYVE/PHD zinc finger
82199 - SET domain | 0 | DIRECT |
52047,48371
52047 - RNI-like
48371 - ARM repeat | 0 | DIRECT |
64356,49447
64356 - SNARE-like
49447 - Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
46785,46785
46785 - "Winged helix" DNA-binding domain
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
55973,55973
55973 - S-adenosylmethionine synthetase
55973 - S-adenosylmethionine synthetase | 0 | DIRECT |
54849,52029
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0 | DIRECT |
54495,46934
54495 - UBC-like
46934 - UBA-like | 0 | DIRECT |
57625,57625
57625 - Invertebrate chitin-binding proteins
57625 - Invertebrate chitin-binding proteins | 0 | DIRECT |
48403,52151
48403 - Ankyrin repeat
52151 - FabD/lysophospholipase-like | 0 | DIRECT |
81811,82754
81811 - Helical domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
50447,50465
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
50677,52374
50677 - ValRS/IleRS/LeuRS editing domain
52374 - Nucleotidylyl transferase | 0 | DIRECT |
56091,50249
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
55394,55394
55394 - Bactericidal permeability-increasing protein, BPI
55394 - Bactericidal permeability-increasing protein, BPI | 0 | DIRECT |
53067,53067
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 0 | DIRECT |
51206,51206
51206 - cAMP-binding domain-like
51206 - cAMP-binding domain-like | 0 | DIRECT |
55874,54211
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
54211 - Ribosomal protein S5 domain 2-like | 0 | DIRECT |
81698,81698
81698 - FF domain
81698 - FF domain | 0 | DIRECT |
48425,50729
48425 - Sec7 domain
50729 - PH domain-like | 0 | DIRECT |
54665,56003
54665 - CO dehydrogenase molybdoprotein N-domain-like
56003 - Molybdenum cofactor-binding domain | 0 | DIRECT |
51735,56327
51735 - NAD(P)-binding Rossmann-fold domains
56327 - LDH C-terminal domain-like | 0 | DIRECT |
100920,100934
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
57535,57535
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | DIRECT |
57850,117839
57850 - RING/U-box
117839 - WWE domain | 0 | DIRECT |
47587,56399
47587 - Domain of poly(ADP-ribose) polymerase
56399 - ADP-ribosylation | 0 | DIRECT |
52743,49785
52743 - Subtilisin-like
49785 - Galactose-binding domain-like | 0 | DIRECT |
47413,46689
47413 - lambda repressor-like DNA-binding domains
46689 - Homeodomain-like | 0 | DIRECT |
64593,74853
64593 - Intermediate filament protein, coiled coil region
74853 - Lamin A/C globular tail domain | 0 | DIRECT |
51905,56425
51905 - FAD/NAD(P)-binding domain
56425 - Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | DIRECT |
55326,56042
55326 - PurM N-terminal domain-like
56042 - PurM C-terminal domain-like | 0 | DIRECT |
54160,54160
54160 - Chromo domain-like
54160 - Chromo domain-like | 0 | DIRECT |
57938,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
49742,49742
49742 - PHM/PNGase F
49742 - PHM/PNGase F | 0 | DIRECT |
57756,57756
57756 - Retrovirus zinc finger-like domains
57756 - Retrovirus zinc finger-like domains | 0 | DIRECT |
51556,51338
51556 - Metallo-dependent hydrolases
51338 - Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
82615,82615
82615 - Polo-box domain
82615 - Polo-box domain | 0 | DIRECT |
52518,52518
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52518 - Thiamin diphosphate-binding fold (THDP-binding) | 0 | DIRECT |
54695,81382
54695 - POZ domain
81382 - Skp1 dimerisation domain-like | 0 | DIRECT |
52540,90123
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region | 0 | DIRECT |
57903,51197
57903 - FYVE/PHD zinc finger
51197 - Clavaminate synthase-like | 0 | DIRECT |
53067,100920
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
49493,49493
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
81383,52047
81383 - F-box domain
52047 - RNI-like | 0 | DIRECT |
74788,75632
74788 - Cullin repeat-like
75632 - Cullin homology domain | 0 | DIRECT |
57414,57414
57414 - Hairpin loop containing domain-like
57414 - Hairpin loop containing domain-like | 0 | DIRECT |
48179,48179
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | DIRECT |
55486,50923
55486 - Metalloproteases ("zincins"), catalytic domain
50923 - Hemopexin-like domain | 0 | DIRECT |
46938,52087
46938 - CRAL/TRIO N-terminal domain
52087 - CRAL/TRIO domain | 0 | DIRECT |
54292,47741
54292 - 2Fe-2S ferredoxin-like
47741 - CO dehydrogenase ISP C-domain like | 0 | DIRECT |
56112,48371
56112 - Protein kinase-like (PK-like)
48371 - ARM repeat | 0 | DIRECT |
56059,51246
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 0 | DIRECT |
46966,46966
46966 - Spectrin repeat
46966 - Spectrin repeat | 0 | DIRECT |
52540,81271
52540 - P-loop containing nucleoside triphosphate hydrolases
81271 - TGS-like | 0 | DIRECT |
50729,47473
50729 - PH domain-like
47473 - EF-hand | 0 | DIRECT |
47769,47769
47769 - SAM/Pointed domain
47769 - SAM/Pointed domain | 0 | DIRECT |
81631,55003
81631 - PAP/OAS1 substrate-binding domain
55003 - PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | DIRECT |
57889,48350
57889 - Cysteine-rich domain
48350 - GTPase activation domain, GAP | 0 | DIRECT |
57196,49899
57196 - EGF/Laminin
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
48371,56112
48371 - ARM repeat
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
47090,55486
47090 - PGBD-like
55486 - Metalloproteases ("zincins"), catalytic domain | 0 | DIRECT |
54236,47031
54236 - Ubiquitin-like
47031 - Second domain of FERM | 0 | DIRECT |
54236,54236
54236 - Ubiquitin-like
54236 - Ubiquitin-like | 0 | DIRECT |
53901,53901
53901 - Thiolase-like
53901 - Thiolase-like | 0 | DIRECT |
81324,81296
81324 - Voltage-gated potassium channels
81296 - E set domains | 0 | DIRECT |
54897,52743
54897 - Protease propeptides/inhibitors
52743 - Subtilisin-like | 0 | DIRECT |
55920,46785
55920 - Creatinase/aminopeptidase
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
52374,47323
52374 - Nucleotidylyl transferase
47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
75632,46785
75632 - Cullin homology domain
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
47031,50729
47031 - Second domain of FERM
50729 - PH domain-like | 0 | DIRECT |
51735,55347
51735 - NAD(P)-binding Rossmann-fold domains
55347 - Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | DIRECT |
51045,51045
51045 - WW domain
51045 - WW domain | 0 | DIRECT |
68923,53795
68923 - PEP carboxykinase N-terminal domain
53795 - PEP carboxykinase-like | 0 | DIRECT |
49348,55711
49348 - Clathrin adaptor appendage domain
55711 - Subdomain of clathrin and coatomer appendage domain | 0 | DIRECT |
51445,51011
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain | 0 | DIRECT |
52440,56059
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like | 0 | DIRECT |
81324,81327
81324 - Voltage-gated potassium channels
81327 - Small-conductance potassium channel | 0 | DIRECT |
55681,52954
55681 - Class II aaRS and biotin synthetases
52954 - Class II aaRS ABD-related | 0 | DIRECT |
49562,48371
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat | 0 | DIRECT |
51735,50129
51735 - NAD(P)-binding Rossmann-fold domains
50129 - GroES-like | 0 | DIRECT |
48065,50729
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like | 0 | DIRECT |
55486,57552
55486 - Metalloproteases ("zincins"), catalytic domain
57552 - Blood coagulation inhibitor (disintegrin) | 0 | DIRECT |
48371,48371
48371 - ARM repeat
48371 - ARM repeat | 0 | DIRECT |
47220,47220
47220 - alpha-catenin/vinculin-like
47220 - alpha-catenin/vinculin-like | 0 | DIRECT |
47203,47203
47203 - Acyl-CoA dehydrogenase C-terminal domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
144232,82199
144232 - HIT/MYND zinc finger-like
82199 - SET domain | 0 | DIRECT |
48334,52540
48334 - DNA repair protein MutS, domain III
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
57863,48403
57863 - ArfGap/RecO-like zinc finger
48403 - Ankyrin repeat | 0 | DIRECT |
54897,53187
54897 - Protease propeptides/inhibitors
53187 - Zn-dependent exopeptidases | 0 | DIRECT |
54211,55060
54211 - Ribosomal protein S5 domain 2-like
55060 - GHMP Kinase, C-terminal domain | 0 | DIRECT |
141739,141739
141739 - MFPT repeat-like
141739 - MFPT repeat-like | 0 | DIRECT |
53738,53738
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains | 0 | DIRECT |
52283,51735
52283 - Formate/glycerate dehydrogenase catalytic domain-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
48592,54849
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like | 0 | DIRECT |
57889,50729
57889 - Cysteine-rich domain
50729 - PH domain-like | 0 | DIRECT |
54001,49758
54001 - Cysteine proteinases
49758 - Calpain large subunit, middle domain (domain III) | 0 | DIRECT |
57184,57196
57184 - Growth factor receptor domain
57196 - EGF/Laminin | 0 | DIRECT |
50249,55681
50249 - Nucleic acid-binding proteins
55681 - Class II aaRS and biotin synthetases | 0 | DIRECT |
55785,55785
55785 - PYP-like sensor domain (PAS domain)
55785 - PYP-like sensor domain (PAS domain) | 0 | DIRECT |
48464,89009
48464 - ENTH/VHS domain
89009 - GAT-like domain | 0 | DIRECT |
161111,160240
161111 - Cation efflux protein transmembrane domain-like
160240 - Cation efflux protein cytoplasmic domain-like | 0 | DIRECT |
53187,55031
53187 - Zn-dependent exopeptidases
55031 - Bacterial exopeptidase dimerisation domain | 0 | DIRECT |
52540,140990
52540 - P-loop containing nucleoside triphosphate hydrolases
140990 - FtsH protease domain-like | 0 | DIRECT |
49265,48726
49265 - Fibronectin type III
48726 - Immunoglobulin | 0 | DIRECT |
47895,52540
47895 - Transducin (alpha subunit), insertion domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
54585,52540
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
49313,49313
49313 - Cadherin-like
49313 - Cadherin-like | 0 | DIRECT |
51445,54556
51445 - (Trans)glycosidases
54556 - Chitinase insertion domain | 0 | DIRECT |
56672,100879
56672 - DNA/RNA polymerases
100879 - Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
51445,51445
51445 - (Trans)glycosidases
51445 - (Trans)glycosidases | 0 | DIRECT |
52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.003245 | INHERITED FROM: organism UV hypersensitive || organism environmental stimulus response variant || organism stress response variant || dauer lifespan variant || dauer lifespan extended || sick || slow growth || organism UV response variant |
55550,56112
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0.0187 | INHERITED FROM: aldicarb resistant || acetylcholinesterase inhibitor resistant || slow growth |
48452,48452
48452 - TPR-like
48452 - TPR-like | 0.1302 | INHERITED FROM: positive chemotaxis defective || organism environmental stimulus response variant || aqueous chemosensory response variant || aldicarb response variant || pattern of transgene expression variant || gene expression variant || chemotaxis variant || dauer defective |
90123,52540
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.134 | INHERITED FROM: organism environmental stimulus response variant || RNAi response variant || cadmium response variant || colchicine hypersensitive || metal response variant |
56112,55073
56112 - Protein kinase-like (PK-like)
55073 - Nucleotide cyclase | 0.1591 | INHERITED FROM: cation positive chemotaxis variant || organism environmental stimulus response variant || lithium chemotaxis defective || chemical response variant || bromide chemotaxis variant || iodide chemotaxis defective || positive chemotaxis variant || AWC odorant chemotaxis defective || alkaline pH chemotaxis variant || magnesium chemotaxis defective || iodide chemotaxis variant || anion positive chemotaxis defective || AWC odorant chemotaxis variant || cation positive chemotaxis defective || benzaldehyde chemotaxis variant || anion positive chemotaxis variant || chemosensory response variant || chemotaxis variant || bromide chemotaxis defective |
81660,56784
81660 - Metal cation-transporting ATPase, ATP-binding domain N
56784 - HAD-like | 0.1591 | INHERITED FROM: nicotine hypersensitive || organism environmental stimulus response variant || drug hypersensitive || lipid composition variant |
56436,56436
56436 - C-type lectin-like
56436 - C-type lectin-like | 0.2043 | INHERITED FROM: cadmium hypersensitive |
52540,50447
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins | 0.2357 | INHERITED FROM: protein modification variant || transgene expression variant || protein protein interaction variant || protein aggregation variant || mRNA levels reduced || proteasome core activity variant || protein phosphorylation variant || mRNA levels increased || protein phosphorylation increased |
51735,48179
51735 - NAD(P)-binding Rossmann-fold domains
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0.2861 | INHERITED FROM: lipid metabolism variant || fat content variant |
56784,81665
56784 - HAD-like
81665 - Calcium ATPase, transmembrane domain M | 0.2861 | INHERITED FROM: nicotine hypersensitive || organism environmental stimulus response variant || drug hypersensitive |
56436,49854
56436 - C-type lectin-like
49854 - Spermadhesin, CUB domain | 0.2892 | INHERITED FROM: cadmium response variant || cadmium hypersensitive |
49785,49785
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like | 0.3143 | INHERITED FROM: protein interaction variant || protein protein interaction variant || protein aggregation variant |
52833,52833
52833 - Thioredoxin-like
52833 - Thioredoxin-like | 0.3458 | INHERITED FROM: protein interaction variant || protein protein interaction variant || protein aggregation variant || pattern of transgene expression variant |
50978,50978
50978 - WD40 repeat-like
50978 - WD40 repeat-like | 0.3458 | INHERITED FROM: positive chemotaxis defective || aqueous positive chemotaxis defective || negative chemotaxis variant || aqueous positive chemotaxis variant || aqueous chemosensory response variant || osmotic avoidance variant || positive chemotaxis variant || mechanosensation variant || odorant chemosensory response variant || chemotaxis variant || dauer defective |
47473,47473
47473 - EF-hand
47473 - EF-hand | 0.3807 | INHERITED FROM: aldicarb response variant || acetylcholinesterase inhibitor hypersensitive || acetylcholinesterase inhibitor response variant |
54928,54928
54928 - RNA-binding domain, RBD
54928 - RNA-binding domain, RBD | 0.4103 | INHERITED FROM: organism starvation response variant || late larval arrest || gene expression variant || starvation induced apoptosis variant |
63712,90112
63712 - Nicotinic receptor ligand binding domain-like
90112 - Neurotransmitter-gated ion-channel transmembrane pore | 0.468 | INHERITED FROM: nicotine resistant || organism environmental stimulus response variant || selenium response variant || aqueous chemosensory response variant || sodium chloride chemotaxis variant || chemical response variant || drug response variant || positive chemotaxis variant || hypoosmotic shock hypersensitive || mechanosensation variant || antihelmintic response variant || DMPP response variant || protein degradation variant || cholinergic agonist resistant |
48403,48403
48403 - Ankyrin repeat
48403 - Ankyrin repeat | 0.5023 | INHERITED FROM: organism environmental stimulus response variant |
57716,57716
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0.5281 | INHERITED FROM: organism metabolism processing variant || protein degradation variant || protein expression reduced || protein expression variant |
57196,57196
57196 - EGF/Laminin
57196 - EGF/Laminin | 0.5369 | INHERITED FROM: growth rate variant || protein expression reduced |
52833,47616
52833 - Thioredoxin-like
47616 - GST C-terminal domain-like | 0.5747 | INHERITED FROM: organism electrophilic stress hypersensitive || organism environmental stimulus response variant || paraquat response variant || organism stress response variant || cadmium response variant || cadmium hypersensitive || enzyme activity variant || enzyme activity reduced || metal response variant || organism heat hypersensitive |
50044,55550
50044 - SH3-domain
55550 - SH2 domain | 0.5997 | INHERITED FROM: protein expression reduced |
57716,48508
57716 - Glucocorticoid receptor-like (DNA-binding domain)
48508 - Nuclear receptor ligand-binding domain | 0.6127 | INHERITED FROM: chemical hypersensitive || SDS sensitive dauer || dauer resistance to harsh conditions variant || transgene expression reduced |
56968,48431
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
48431 - Lipovitellin-phosvitin complex, superhelical domain | 0.657 | INHERITED FROM: organism environmental stimulus response variant || pathogen susceptibility increased || organism pathogen response variant || transgene subcellular localization variant || life span variant |
48431,56968
48431 - Lipovitellin-phosvitin complex, superhelical domain
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions | 0.657 | INHERITED FROM: organism environmental stimulus response variant || pathogen susceptibility increased || organism pathogen response variant || transgene subcellular localization variant || life span variant |
63380,52343
63380 - Riboflavin synthase domain-like
52343 - Ferredoxin reductase-like, C-terminal NADP-linked domain | 0.657 | INHERITED FROM: transgene subcellular localization variant |
57424,57424
57424 - LDL receptor-like module
57424 - LDL receptor-like module | 0.7041 | INHERITED FROM: protein expression reduced |
51905,54373
51905 - FAD/NAD(P)-binding domain
54373 - FAD-linked reductases, C-terminal domain | 0.7041 | INHERITED FROM: shortened life span || life span variant |
57903,57903
57903 - FYVE/PHD zinc finger
57903 - FYVE/PHD zinc finger | 0.7189 | INHERITED FROM: organism UV hypersensitive || organism environmental stimulus response variant || organism UV response variant |
55550,50044
55550 - SH2 domain
50044 - SH3-domain | 0.7859 | INHERITED FROM: protein expression reduced || level of protein expression variant || protein expression variant |
48726,49265
48726 - Immunoglobulin
49265 - Fibronectin type III | 0.8768 | INHERITED FROM: aldicarb resistant || chemical response variant || growth rate variant || protein degradation variant |
48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin | 0.9284 | INHERITED FROM: growth rate variant || protein degradation variant |
54211,55666
54211 - Ribosomal protein S5 domain 2-like
55666 - Ribonuclease PH domain 2-like | 0.965 | INHERITED FROM: early larval arrest |
49562,49562
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0.9756 | INHERITED FROM: drug resistant |
52777,52777
52777 - CoA-dependent acyltransferases
52777 - CoA-dependent acyltransferases | 1 | INHERITED FROM: lipid metabolism variant || fat content variant |
57850,57850
57850 - RING/U-box
57850 - RING/U-box | 1 | INHERITED FROM: protein interaction variant || protein protein interaction variant || protein aggregation variant |
57850,57845
57850 - RING/U-box
57845 - B-box zinc-binding domain | 1 | INHERITED FROM: protein interaction variant || transgene expression variant || protein protein interaction variant || protein aggregation variant || transgene subcellular localization variant |
53300,56436
53300 - vWA-like
56436 - C-type lectin-like | 1 | INHERITED FROM: pathogen susceptibility increased || pathogen induced death increased |
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
55729,55729
55729 - Acyl-CoA N-acyltransferases (Nat)
55729 - Acyl-CoA N-acyltransferases (Nat) | 0 | Direct |
81324,53850
81324 - Voltage-gated potassium channels
53850 - Periplasmic binding protein-like II | 0 | Direct |
53474,53474
53474 - alpha/beta-Hydrolases
53474 - alpha/beta-Hydrolases | 0 | Direct |
53738,55957
53738 - Phosphoglucomutase, first 3 domains
55957 - Phosphoglucomutase, C-terminal domain | 0 | Direct |
52047,52047
52047 - RNI-like
52047 - RNI-like | 0 | Direct |
90229,90229
90229 - CCCH zinc finger
90229 - CCCH zinc finger | 0 | Direct |
57889,57889
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0 | Direct |
88713,88688
88713 - Glycoside hydrolase/deacetylase
88688 - Families 57/38 glycoside transferase middle domain | 0 | Direct |
52490,55307
52490 - Tubulin nucleotide-binding domain-like
55307 - Tubulin C-terminal domain-like | 0 | Direct |
51338,51556
51338 - Composite domain of metallo-dependent hydrolases
51556 - Metallo-dependent hydrolases | 0 | Direct |
50249,50249
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins | 0 | Direct |
50156,50044
50156 - PDZ domain-like
50044 - SH3-domain | 0 | Direct |
82895,82895
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat | 0 | Direct |
57184,57184
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | Direct |
57196,57184
57196 - EGF/Laminin
57184 - Growth factor receptor domain | 0 | Direct |
52540,47917
52540 - P-loop containing nucleoside triphosphate hydrolases
47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
47741,56176
47741 - CO dehydrogenase ISP C-domain like
56176 - FAD-binding/transporter-associated domain-like | 0 | Direct |
74650,51445
74650 - Galactose mutarotase-like
51445 - (Trans)glycosidases | 0 | Direct |
51905,55424
51905 - FAD/NAD(P)-binding domain
55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | Direct |
51971,54373
51971 - Nucleotide-binding domain
54373 - FAD-linked reductases, C-terminal domain | 0 | Direct |
82919,53300
82919 - Zn-finger domain of Sec23/24
53300 - vWA-like | 0 | Direct |
47473,51695
47473 - EF-hand
51695 - PLC-like phosphodiesterases | 0 | Direct |
56601,48403
56601 - beta-lactamase/transpeptidase-like
48403 - Ankyrin repeat | 0 | Direct |
50044,50044
50044 - SH3-domain
50044 - SH3-domain | 0 | Direct |
50044,52540
50044 - SH3-domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
81301,81631
81301 - Nucleotidyltransferase
81631 - PAP/OAS1 substrate-binding domain | 0 | Direct |
52113,52113
52113 - BRCT domain
52113 - BRCT domain | 0 | Direct |
47954,47954
47954 - Cyclin-like
47954 - Cyclin-like | 0 | Direct |
81383,50978
81383 - F-box domain
50978 - WD40 repeat-like | 0 | Direct |
54534,54534
54534 - FKBP-like
54534 - FKBP-like | 0 | Direct |
57196,63825
57196 - EGF/Laminin
63825 - YWTD domain | 0 | Direct |
56645,47203
56645 - Acyl-CoA dehydrogenase NM domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
57756,50630
57756 - Retrovirus zinc finger-like domains
50630 - Acid proteases | 0 | Direct |
50129,51735
50129 - GroES-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | Direct |
141673,50800
141673 - MOSC N-terminal domain-like
50800 - PK beta-barrel domain-like | 0 | Direct |
57362,57362
57362 - BPTI-like
57362 - BPTI-like | 0 | Direct |
56112,82615
56112 - Protein kinase-like (PK-like)
82615 - Polo-box domain | 0 | Direct |
47576,47576
47576 - Calponin-homology domain, CH-domain
47576 - Calponin-homology domain, CH-domain | 0 | Direct |
50729,56112
50729 - PH domain-like
56112 - Protein kinase-like (PK-like) | 0 | Direct |
52518,52922
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52922 - TK C-terminal domain-like | 0 | Direct |
161093,161093
161093 - MgtE membrane domain-like
161093 - MgtE membrane domain-like | 0 | Direct |
81333,81333
81333 - F1F0 ATP synthase subunit C
81333 - F1F0 ATP synthase subunit C | 0 | Direct |
101690,53098
101690 - PAZ domain
53098 - Ribonuclease H-like | 0 | Direct |
47473,103506
47473 - EF-hand
103506 - Mitochondrial carrier | 0 | Direct |
51695,49562
51695 - PLC-like phosphodiesterases
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
54768,54768
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like | 0 | Direct |
54160,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
50978,50998
50978 - WD40 repeat-like
50998 - Quinoprotein alcohol dehydrogenase-like | 0 | Direct |
52540,46785
52540 - P-loop containing nucleoside triphosphate hydrolases
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
56059,52210
56059 - Glutathione synthetase ATP-binding domain-like
52210 - Succinyl-CoA synthetase domains | 0 | Direct |
103473,103473
103473 - MFS general substrate transporter
103473 - MFS general substrate transporter | 0 | Direct |
50692,54585
50692 - ADC-like
54585 - Cdc48 domain 2-like | 0 | Direct |
53187,49464
53187 - Zn-dependent exopeptidases
49464 - Carboxypeptidase regulatory domain-like | 0 | Direct |
57903,82199
57903 - FYVE/PHD zinc finger
82199 - SET domain | 0 | Direct |
52047,48371
52047 - RNI-like
48371 - ARM repeat | 0 | Direct |
64356,49447
64356 - SNARE-like
49447 - Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
46785,46785
46785 - "Winged helix" DNA-binding domain
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
55973,55973
55973 - S-adenosylmethionine synthetase
55973 - S-adenosylmethionine synthetase | 0 | Direct |
54849,52029
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0 | Direct |
54495,46934
54495 - UBC-like
46934 - UBA-like | 0 | Direct |
57625,57625
57625 - Invertebrate chitin-binding proteins
57625 - Invertebrate chitin-binding proteins | 0 | Direct |
48403,52151
48403 - Ankyrin repeat
52151 - FabD/lysophospholipase-like | 0 | Direct |
81811,82754
81811 - Helical domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
50447,50465
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
50677,52374
50677 - ValRS/IleRS/LeuRS editing domain
52374 - Nucleotidylyl transferase | 0 | Direct |
56091,50249
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins | 0 | Direct |
55394,55394
55394 - Bactericidal permeability-increasing protein, BPI
55394 - Bactericidal permeability-increasing protein, BPI | 0 | Direct |
53067,53067
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 0 | Direct |
51206,51206
51206 - cAMP-binding domain-like
51206 - cAMP-binding domain-like | 0 | Direct |
55874,54211
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
54211 - Ribosomal protein S5 domain 2-like | 0 | Direct |
81698,81698
81698 - FF domain
81698 - FF domain | 0 | Direct |
48425,50729
48425 - Sec7 domain
50729 - PH domain-like | 0 | Direct |
54665,56003
54665 - CO dehydrogenase molybdoprotein N-domain-like
56003 - Molybdenum cofactor-binding domain | 0 | Direct |
51735,56327
51735 - NAD(P)-binding Rossmann-fold domains
56327 - LDH C-terminal domain-like | 0 | Direct |
100920,100934
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
57535,57535
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | Direct |
57850,117839
57850 - RING/U-box
117839 - WWE domain | 0 | Direct |
47587,56399
47587 - Domain of poly(ADP-ribose) polymerase
56399 - ADP-ribosylation | 0 | Direct |
52743,49785
52743 - Subtilisin-like
49785 - Galactose-binding domain-like | 0 | Direct |
47413,46689
47413 - lambda repressor-like DNA-binding domains
46689 - Homeodomain-like | 0 | Direct |
64593,74853
64593 - Intermediate filament protein, coiled coil region
74853 - Lamin A/C globular tail domain | 0 | Direct |
51905,56425
51905 - FAD/NAD(P)-binding domain
56425 - Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | Direct |
55326,56042
55326 - PurM N-terminal domain-like
56042 - PurM C-terminal domain-like | 0 | Direct |
54160,54160
54160 - Chromo domain-like
54160 - Chromo domain-like | 0 | Direct |
57938,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
49742,49742
49742 - PHM/PNGase F
49742 - PHM/PNGase F | 0 | Direct |
57756,57756
57756 - Retrovirus zinc finger-like domains
57756 - Retrovirus zinc finger-like domains | 0 | Direct |
51556,51338
51556 - Metallo-dependent hydrolases
51338 - Composite domain of metallo-dependent hydrolases | 0 | Direct |
82615,82615
82615 - Polo-box domain
82615 - Polo-box domain | 0 | Direct |
52518,52518
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52518 - Thiamin diphosphate-binding fold (THDP-binding) | 0 | Direct |
54695,81382
54695 - POZ domain
81382 - Skp1 dimerisation domain-like | 0 | Direct |
52540,90123
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region | 0 | Direct |
57903,51197
57903 - FYVE/PHD zinc finger
51197 - Clavaminate synthase-like | 0 | Direct |
53067,100920
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
49493,49493
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
81383,52047
81383 - F-box domain
52047 - RNI-like | 0 | Direct |
74788,75632
74788 - Cullin repeat-like
75632 - Cullin homology domain | 0 | Direct |
57414,57414
57414 - Hairpin loop containing domain-like
57414 - Hairpin loop containing domain-like | 0 | Direct |
48179,48179
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | Direct |
55486,50923
55486 - Metalloproteases ("zincins"), catalytic domain
50923 - Hemopexin-like domain | 0 | Direct |
46938,52087
46938 - CRAL/TRIO N-terminal domain
52087 - CRAL/TRIO domain | 0 | Direct |
54292,47741
54292 - 2Fe-2S ferredoxin-like
47741 - CO dehydrogenase ISP C-domain like | 0 | Direct |
56112,48371
56112 - Protein kinase-like (PK-like)
48371 - ARM repeat | 0 | Direct |
56059,51246
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 0 | Direct |
46966,46966
46966 - Spectrin repeat
46966 - Spectrin repeat | 0 | Direct |
52540,81271
52540 - P-loop containing nucleoside triphosphate hydrolases
81271 - TGS-like | 0 | Direct |
50729,47473
50729 - PH domain-like
47473 - EF-hand | 0 | Direct |
47769,47769
47769 - SAM/Pointed domain
47769 - SAM/Pointed domain | 0 | Direct |
81631,55003
81631 - PAP/OAS1 substrate-binding domain
55003 - PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | Direct |
57889,48350
57889 - Cysteine-rich domain
48350 - GTPase activation domain, GAP | 0 | Direct |
57196,49899
57196 - EGF/Laminin
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
48371,56112
48371 - ARM repeat
56112 - Protein kinase-like (PK-like) | 0 | Direct |
47090,55486
47090 - PGBD-like
55486 - Metalloproteases ("zincins"), catalytic domain | 0 | Direct |
54236,47031
54236 - Ubiquitin-like
47031 - Second domain of FERM | 0 | Direct |
54236,54236
54236 - Ubiquitin-like
54236 - Ubiquitin-like | 0 | Direct |
53901,53901
53901 - Thiolase-like
53901 - Thiolase-like | 0 | Direct |
81324,81296
81324 - Voltage-gated potassium channels
81296 - E set domains | 0 | Direct |
54897,52743
54897 - Protease propeptides/inhibitors
52743 - Subtilisin-like | 0 | Direct |
55920,46785
55920 - Creatinase/aminopeptidase
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
52374,47323
52374 - Nucleotidylyl transferase
47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
75632,46785
75632 - Cullin homology domain
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
47031,50729
47031 - Second domain of FERM
50729 - PH domain-like | 0 | Direct |
51735,55347
51735 - NAD(P)-binding Rossmann-fold domains
55347 - Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | Direct |
51045,51045
51045 - WW domain
51045 - WW domain | 0 | Direct |
68923,53795
68923 - PEP carboxykinase N-terminal domain
53795 - PEP carboxykinase-like | 0 | Direct |
49348,55711
49348 - Clathrin adaptor appendage domain
55711 - Subdomain of clathrin and coatomer appendage domain | 0 | Direct |
51445,51011
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain | 0 | Direct |
52440,56059
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like | 0 | Direct |
81324,81327
81324 - Voltage-gated potassium channels
81327 - Small-conductance potassium channel | 0 | Direct |
55681,52954
55681 - Class II aaRS and biotin synthetases
52954 - Class II aaRS ABD-related | 0 | Direct |
49562,48371
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat | 0 | Direct |
51735,50129
51735 - NAD(P)-binding Rossmann-fold domains
50129 - GroES-like | 0 | Direct |
48065,50729
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like | 0 | Direct |
55486,57552
55486 - Metalloproteases ("zincins"), catalytic domain
57552 - Blood coagulation inhibitor (disintegrin) | 0 | Direct |
48371,48371
48371 - ARM repeat
48371 - ARM repeat | 0 | Direct |
47220,47220
47220 - alpha-catenin/vinculin-like
47220 - alpha-catenin/vinculin-like | 0 | Direct |
47203,47203
47203 - Acyl-CoA dehydrogenase C-terminal domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
144232,82199
144232 - HIT/MYND zinc finger-like
82199 - SET domain | 0 | Direct |
48334,52540
48334 - DNA repair protein MutS, domain III
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
57863,48403
57863 - ArfGap/RecO-like zinc finger
48403 - Ankyrin repeat | 0 | Direct |
54897,53187
54897 - Protease propeptides/inhibitors
53187 - Zn-dependent exopeptidases | 0 | Direct |
54211,55060
54211 - Ribosomal protein S5 domain 2-like
55060 - GHMP Kinase, C-terminal domain | 0 | Direct |
141739,141739
141739 - MFPT repeat-like
141739 - MFPT repeat-like | 0 | Direct |
53738,53738
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains | 0 | Direct |
52283,51735
52283 - Formate/glycerate dehydrogenase catalytic domain-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | Direct |
48592,54849
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like | 0 | Direct |
57889,50729
57889 - Cysteine-rich domain
50729 - PH domain-like | 0 | Direct |
54001,49758
54001 - Cysteine proteinases
49758 - Calpain large subunit, middle domain (domain III) | 0 | Direct |
57184,57196
57184 - Growth factor receptor domain
57196 - EGF/Laminin | 0 | Direct |
50249,55681
50249 - Nucleic acid-binding proteins
55681 - Class II aaRS and biotin synthetases | 0 | Direct |
55785,55785
55785 - PYP-like sensor domain (PAS domain)
55785 - PYP-like sensor domain (PAS domain) | 0 | Direct |
48464,89009
48464 - ENTH/VHS domain
89009 - GAT-like domain | 0 | Direct |
161111,160240
161111 - Cation efflux protein transmembrane domain-like
160240 - Cation efflux protein cytoplasmic domain-like | 0 | Direct |
53187,55031
53187 - Zn-dependent exopeptidases
55031 - Bacterial exopeptidase dimerisation domain | 0 | Direct |
52540,140990
52540 - P-loop containing nucleoside triphosphate hydrolases
140990 - FtsH protease domain-like | 0 | Direct |
49265,48726
49265 - Fibronectin type III
48726 - Immunoglobulin | 0 | Direct |
47895,52540
47895 - Transducin (alpha subunit), insertion domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
54585,52540
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
49313,49313
49313 - Cadherin-like
49313 - Cadherin-like | 0 | Direct |
51445,54556
51445 - (Trans)glycosidases
54556 - Chitinase insertion domain | 0 | Direct |
56672,100879
56672 - DNA/RNA polymerases
100879 - Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
51445,51445
51445 - (Trans)glycosidases
51445 - (Trans)glycosidases | 0 | Direct |
52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.003245 | Inherited |
55550,56112
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0.0187 | Inherited |
48452,48452
48452 - TPR-like
48452 - TPR-like | 0.1302 | Inherited |
90123,52540
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.134 | Inherited |
56112,55073
56112 - Protein kinase-like (PK-like)
55073 - Nucleotide cyclase | 0.1591 | Inherited |
81660,56784
81660 - Metal cation-transporting ATPase, ATP-binding domain N
56784 - HAD-like | 0.1591 | Inherited |
56436,56436
56436 - C-type lectin-like
56436 - C-type lectin-like | 0.2043 | Inherited |
52540,50447
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins | 0.2357 | Inherited |
51735,48179
51735 - NAD(P)-binding Rossmann-fold domains
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0.2861 | Inherited |
56784,81665
56784 - HAD-like
81665 - Calcium ATPase, transmembrane domain M | 0.2861 | Inherited |
56436,49854
56436 - C-type lectin-like
49854 - Spermadhesin, CUB domain | 0.2892 | Inherited |
49785,49785
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like | 0.3143 | Inherited |
52833,52833
52833 - Thioredoxin-like
52833 - Thioredoxin-like | 0.3458 | Inherited |
50978,50978
50978 - WD40 repeat-like
50978 - WD40 repeat-like | 0.3458 | Inherited |
47473,47473
47473 - EF-hand
47473 - EF-hand | 0.3807 | Inherited |
54928,54928
54928 - RNA-binding domain, RBD
54928 - RNA-binding domain, RBD | 0.4103 | Inherited |
63712,90112
63712 - Nicotinic receptor ligand binding domain-like
90112 - Neurotransmitter-gated ion-channel transmembrane pore | 0.468 | Inherited |
48403,48403
48403 - Ankyrin repeat
48403 - Ankyrin repeat | 0.5023 | Inherited |
57716,57716
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0.5281 | Inherited |
57196,57196
57196 - EGF/Laminin
57196 - EGF/Laminin | 0.5369 | Inherited |
52833,47616
52833 - Thioredoxin-like
47616 - GST C-terminal domain-like | 0.5747 | Inherited |
50044,55550
50044 - SH3-domain
55550 - SH2 domain | 0.5997 | Inherited |
57716,48508
57716 - Glucocorticoid receptor-like (DNA-binding domain)
48508 - Nuclear receptor ligand-binding domain | 0.6127 | Inherited |
56968,48431
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
48431 - Lipovitellin-phosvitin complex, superhelical domain | 0.657 | Inherited |
48431,56968
48431 - Lipovitellin-phosvitin complex, superhelical domain
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions | 0.657 | Inherited |
63380,52343
63380 - Riboflavin synthase domain-like
52343 - Ferredoxin reductase-like, C-terminal NADP-linked domain | 0.657 | Inherited |
57424,57424
57424 - LDL receptor-like module
57424 - LDL receptor-like module | 0.7041 | Inherited |
51905,54373
51905 - FAD/NAD(P)-binding domain
54373 - FAD-linked reductases, C-terminal domain | 0.7041 | Inherited |
57903,57903
57903 - FYVE/PHD zinc finger
57903 - FYVE/PHD zinc finger | 0.7189 | Inherited |
55550,50044
55550 - SH2 domain
50044 - SH3-domain | 0.7859 | Inherited |
48726,49265
48726 - Immunoglobulin
49265 - Fibronectin type III | 0.8768 | Inherited |
48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin | 0.9284 | Inherited |
54211,55666
54211 - Ribosomal protein S5 domain 2-like
55666 - Ribonuclease PH domain 2-like | 0.965 | Inherited |
49562,49562
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0.9756 | Inherited |
52777,52777
52777 - CoA-dependent acyltransferases
52777 - CoA-dependent acyltransferases | 1 | Inherited |
57850,57850
57850 - RING/U-box
57850 - RING/U-box | 1 | Inherited |
57850,57845
57850 - RING/U-box
57845 - B-box zinc-binding domain | 1 | Inherited |
53300,56436
53300 - vWA-like
56436 - C-type lectin-like | 1 | Inherited |
(show details)
Supra-domains annotated to this WP term (Not in SPWP)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
52540,52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
47090,55486,50923
47090 - PGBD-like
55486 - Metalloproteases ("zincins"), catalytic domain
50923 - Hemopexin-like domain | 0 | DIRECT |
81301,81631,55003
81301 - Nucleotidyltransferase
81631 - PAP/OAS1 substrate-binding domain
55003 - PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | DIRECT |
50044,55550,56112
50044 - SH3-domain
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
48592,54849,52029
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0 | DIRECT |
46966,46966,46966
46966 - Spectrin repeat
46966 - Spectrin repeat
46966 - Spectrin repeat | 0 | DIRECT |
54236,47031,50729
54236 - Ubiquitin-like
47031 - Second domain of FERM
50729 - PH domain-like | 0 | DIRECT |
48726,49265,48726
48726 - Immunoglobulin
49265 - Fibronectin type III
48726 - Immunoglobulin | 0 | DIRECT |
52540,90123,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
53067,53067,100920
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
81296,81296,81296
81296 - E set domains
81296 - E set domains
81296 - E set domains | 0 | DIRECT |
48452,48452,48452
48452 - TPR-like
48452 - TPR-like
48452 - TPR-like | 0 | DIRECT |
48371,48371,48371
48371 - ARM repeat
48371 - ARM repeat
48371 - ARM repeat | 0 | DIRECT |
53067,100920,100934
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
56112,82615,82615
56112 - Protein kinase-like (PK-like)
82615 - Polo-box domain
82615 - Polo-box domain | 0 | DIRECT |
63411,63411,63411
63411 - LuxS/MPP-like metallohydrolase
63411 - LuxS/MPP-like metallohydrolase
63411 - LuxS/MPP-like metallohydrolase | 0 | DIRECT |
54292,47741,56176
54292 - 2Fe-2S ferredoxin-like
47741 - CO dehydrogenase ISP C-domain like
56176 - FAD-binding/transporter-associated domain-like | 0 | DIRECT |
51735,48179,48179
51735 - NAD(P)-binding Rossmann-fold domains
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | DIRECT |
53738,53738,53738
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains | 0 | DIRECT |
54160,54160,52540
54160 - Chromo domain-like
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
53738,53738,55957
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains
55957 - Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
74650,51445,51011
74650 - Galactose mutarotase-like
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain | 0 | DIRECT |
49785,49785,49785
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like | 0 | DIRECT |
56436,49854,49854
56436 - C-type lectin-like
49854 - Spermadhesin, CUB domain
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
57414,57414,57414
57414 - Hairpin loop containing domain-like
57414 - Hairpin loop containing domain-like
57414 - Hairpin loop containing domain-like | 0 | DIRECT |
49899,49899,49899
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
82895,82895,82895
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat | 0 | DIRECT |
55973,55973,55973
55973 - S-adenosylmethionine synthetase
55973 - S-adenosylmethionine synthetase
55973 - S-adenosylmethionine synthetase | 0 | DIRECT |
54928,54928,54928
54928 - RNA-binding domain, RBD
54928 - RNA-binding domain, RBD
54928 - RNA-binding domain, RBD | 0 | DIRECT |
57625,57625,57625
57625 - Invertebrate chitin-binding proteins
57625 - Invertebrate chitin-binding proteins
57625 - Invertebrate chitin-binding proteins | 0 | DIRECT |
54160,52540,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
57535,57535,57535
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | DIRECT |
57567,57567,57567
57567 - Serine protease inhibitors
57567 - Serine protease inhibitors
57567 - Serine protease inhibitors | 0 | DIRECT |
52440,56059,51246
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 0 | DIRECT |
49313,49313,49313
49313 - Cadherin-like
49313 - Cadherin-like
49313 - Cadherin-like | 0 | DIRECT |
46938,52087,101576
46938 - CRAL/TRIO N-terminal domain
52087 - CRAL/TRIO domain
101576 - Supernatant protein factor (SPF), C-terminal domain | 0 | DIRECT |
50249,50249,50249
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
50692,54585,52540
50692 - ADC-like
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
50729,47473,51695
50729 - PH domain-like
47473 - EF-hand
51695 - PLC-like phosphodiesterases | 0 | DIRECT |
57938,49493,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
54897,52743,49785
54897 - Protease propeptides/inhibitors
52743 - Subtilisin-like
49785 - Galactose-binding domain-like | 0 | DIRECT |
50156,50044,52540
50156 - PDZ domain-like
50044 - SH3-domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
50129,51735,50129
50129 - GroES-like
51735 - NAD(P)-binding Rossmann-fold domains
50129 - GroES-like | 0 | DIRECT |
50044,50044,50044
50044 - SH3-domain
50044 - SH3-domain
50044 - SH3-domain | 0 | DIRECT |
49562,48371,56112
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
54585,52540,52540
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
90123,52540,90123
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region | 0 | DIRECT |
56645,47203,47203
56645 - Acyl-CoA dehydrogenase NM domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
52540,50447,50465
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
74788,75632,46785
74788 - Cullin repeat-like
75632 - Cullin homology domain
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
57362,57362,57362
57362 - BPTI-like
57362 - BPTI-like
57362 - BPTI-like | 0 | DIRECT |
81660,56784,81665
81660 - Metal cation-transporting ATPase, ATP-binding domain N
56784 - HAD-like
81665 - Calcium ATPase, transmembrane domain M | 0.1754 | INHERITED FROM: nicotine hypersensitive || organism environmental stimulus response variant || drug hypersensitive || lipid composition variant |
57424,57424,57424
57424 - LDL receptor-like module
57424 - LDL receptor-like module
57424 - LDL receptor-like module | 0.4174 | INHERITED FROM: protein metabolism variant || protein expression reduced || level of protein expression variant |
52833,52833,52833
52833 - Thioredoxin-like
52833 - Thioredoxin-like
52833 - Thioredoxin-like | 0.4174 | INHERITED FROM: protein interaction variant || protein protein interaction variant || protein aggregation variant || pattern of transgene expression variant |
56436,56436,49854
56436 - C-type lectin-like
56436 - C-type lectin-like
49854 - Spermadhesin, CUB domain | 0.4369 | INHERITED FROM: cadmium response variant || cadmium hypersensitive || metal response variant |
57716,57716,57716
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0.5023 | INHERITED FROM: organism metabolism processing variant || protein metabolism variant || protein degradation variant || protein expression reduced || level of protein expression variant || protein expression variant |
56968,48431,56968
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
48431 - Lipovitellin-phosvitin complex, superhelical domain
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions | 0.657 | INHERITED FROM: organism environmental stimulus response variant || pathogen susceptibility increased || organism pathogen response variant || transgene subcellular localization variant || life span variant |
57850,57850,57850
57850 - RING/U-box
57850 - RING/U-box
57850 - RING/U-box | 0.7859 | INHERITED FROM: protein interaction variant || protein protein interaction variant || protein aggregation variant |
48726,48726,49265
48726 - Immunoglobulin
48726 - Immunoglobulin
49265 - Fibronectin type III | 1 | INHERITED FROM: growth rate variant || protein degradation variant |
57667,57667,57667
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers | 1 | INHERITED FROM: level of transgene expression variant |
48726,48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin
48726 - Immunoglobulin | 1 | INHERITED FROM: growth rate variant || protein degradation variant |
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
52540,52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
47090,55486,50923
47090 - PGBD-like
55486 - Metalloproteases ("zincins"), catalytic domain
50923 - Hemopexin-like domain | 0 | Direct |
81301,81631,55003
81301 - Nucleotidyltransferase
81631 - PAP/OAS1 substrate-binding domain
55003 - PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | Direct |
50044,55550,56112
50044 - SH3-domain
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0 | Direct |
48592,54849,52029
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0 | Direct |
46966,46966,46966
46966 - Spectrin repeat
46966 - Spectrin repeat
46966 - Spectrin repeat | 0 | Direct |
54236,47031,50729
54236 - Ubiquitin-like
47031 - Second domain of FERM
50729 - PH domain-like | 0 | Direct |
48726,49265,48726
48726 - Immunoglobulin
49265 - Fibronectin type III
48726 - Immunoglobulin | 0 | Direct |
52540,90123,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
53067,53067,100920
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
81296,81296,81296
81296 - E set domains
81296 - E set domains
81296 - E set domains | 0 | Direct |
48452,48452,48452
48452 - TPR-like
48452 - TPR-like
48452 - TPR-like | 0 | Direct |
48371,48371,48371
48371 - ARM repeat
48371 - ARM repeat
48371 - ARM repeat | 0 | Direct |
53067,100920,100934
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
56112,82615,82615
56112 - Protein kinase-like (PK-like)
82615 - Polo-box domain
82615 - Polo-box domain | 0 | Direct |
63411,63411,63411
63411 - LuxS/MPP-like metallohydrolase
63411 - LuxS/MPP-like metallohydrolase
63411 - LuxS/MPP-like metallohydrolase | 0 | Direct |
54292,47741,56176
54292 - 2Fe-2S ferredoxin-like
47741 - CO dehydrogenase ISP C-domain like
56176 - FAD-binding/transporter-associated domain-like | 0 | Direct |
51735,48179,48179
51735 - NAD(P)-binding Rossmann-fold domains
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | Direct |
53738,53738,53738
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains | 0 | Direct |
54160,54160,52540
54160 - Chromo domain-like
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
53738,53738,55957
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains
55957 - Phosphoglucomutase, C-terminal domain | 0 | Direct |
74650,51445,51011
74650 - Galactose mutarotase-like
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain | 0 | Direct |
49785,49785,49785
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like | 0 | Direct |
56436,49854,49854
56436 - C-type lectin-like
49854 - Spermadhesin, CUB domain
49854 - Spermadhesin, CUB domain | 0 | Direct |
57414,57414,57414
57414 - Hairpin loop containing domain-like
57414 - Hairpin loop containing domain-like
57414 - Hairpin loop containing domain-like | 0 | Direct |
49899,49899,49899
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
82895,82895,82895
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat | 0 | Direct |
55973,55973,55973
55973 - S-adenosylmethionine synthetase
55973 - S-adenosylmethionine synthetase
55973 - S-adenosylmethionine synthetase | 0 | Direct |
54928,54928,54928
54928 - RNA-binding domain, RBD
54928 - RNA-binding domain, RBD
54928 - RNA-binding domain, RBD | 0 | Direct |
57625,57625,57625
57625 - Invertebrate chitin-binding proteins
57625 - Invertebrate chitin-binding proteins
57625 - Invertebrate chitin-binding proteins | 0 | Direct |
54160,52540,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
57535,57535,57535
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | Direct |
57567,57567,57567
57567 - Serine protease inhibitors
57567 - Serine protease inhibitors
57567 - Serine protease inhibitors | 0 | Direct |
52440,56059,51246
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 0 | Direct |
49313,49313,49313
49313 - Cadherin-like
49313 - Cadherin-like
49313 - Cadherin-like | 0 | Direct |
46938,52087,101576
46938 - CRAL/TRIO N-terminal domain
52087 - CRAL/TRIO domain
101576 - Supernatant protein factor (SPF), C-terminal domain | 0 | Direct |
50249,50249,50249
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins | 0 | Direct |
50692,54585,52540
50692 - ADC-like
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
50729,47473,51695
50729 - PH domain-like
47473 - EF-hand
51695 - PLC-like phosphodiesterases | 0 | Direct |
57938,49493,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
54897,52743,49785
54897 - Protease propeptides/inhibitors
52743 - Subtilisin-like
49785 - Galactose-binding domain-like | 0 | Direct |
50156,50044,52540
50156 - PDZ domain-like
50044 - SH3-domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
50129,51735,50129
50129 - GroES-like
51735 - NAD(P)-binding Rossmann-fold domains
50129 - GroES-like | 0 | Direct |
50044,50044,50044
50044 - SH3-domain
50044 - SH3-domain
50044 - SH3-domain | 0 | Direct |
49562,48371,56112
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat
56112 - Protein kinase-like (PK-like) | 0 | Direct |
54585,52540,52540
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
90123,52540,90123
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region | 0 | Direct |
56645,47203,47203
56645 - Acyl-CoA dehydrogenase NM domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
52540,50447,50465
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
74788,75632,46785
74788 - Cullin repeat-like
75632 - Cullin homology domain
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
57362,57362,57362
57362 - BPTI-like
57362 - BPTI-like
57362 - BPTI-like | 0 | Direct |
81660,56784,81665
81660 - Metal cation-transporting ATPase, ATP-binding domain N
56784 - HAD-like
81665 - Calcium ATPase, transmembrane domain M | 0.1754 | Inherited |
57424,57424,57424
57424 - LDL receptor-like module
57424 - LDL receptor-like module
57424 - LDL receptor-like module | 0.4174 | Inherited |
52833,52833,52833
52833 - Thioredoxin-like
52833 - Thioredoxin-like
52833 - Thioredoxin-like | 0.4174 | Inherited |
56436,56436,49854
56436 - C-type lectin-like
56436 - C-type lectin-like
49854 - Spermadhesin, CUB domain | 0.4369 | Inherited |
57716,57716,57716
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0.5023 | Inherited |
56968,48431,56968
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
48431 - Lipovitellin-phosvitin complex, superhelical domain
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions | 0.657 | Inherited |
57850,57850,57850
57850 - RING/U-box
57850 - RING/U-box
57850 - RING/U-box | 0.7859 | Inherited |
48726,48726,49265
48726 - Immunoglobulin
48726 - Immunoglobulin
49265 - Fibronectin type III | 1 | Inherited |
57667,57667,57667
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers | 1 | Inherited |
48726,48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin
48726 - Immunoglobulin | 1 | Inherited |
Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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Trees by TreeVector
A presence/absence matrix is generated using protein domains and supradomains
for all genomes in SUPERFAMILY. The RAxML
software is used to produce a single, large tree topology using
heuristic parsimony methods. Genome combinations, or specific clades, can be displayed as
if individual trees had been produced. However, this data is extracted from the single
large tree. This produces a higher quality topology than if the trees had been produced
on their own, and allows the trees to be displayed instantly.
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