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Worm Phenotype (WP): organism physiology variant
(show info)
Phenotype Ontology
Like Gene Ontology (GO), phenotypy ontology classifies and organizes gene-mutant/null phenotypic information from the very general at the top to more specific terms in the directed acyclic graph (DAG) by viewing an individual term as a node and its relations to parental terms (allowing for multiple parents) as directed edges. To navigate this hierarchy, we display all parental phenotypic terms to the current phenotypic term of interest ordered by their shortest distances to the current term. Also, only direct children phenotypic terms of the current phenotypic term are listed. Phenotype ontologies we have incorporated are as follows:
- Disease Ontology (DO) Ontology (DO) DO semantically integrates disease and medical vocabularies through extensive cross mapping of DO terms to MeSH, ICD, NCI’s thesaurus, SNOMED and OMIM.
- Human Phenotype (HP) Ontology (HP) HP captures phenotypic abnormalities that are described in OMIM, along with the corresponding disease-causing genes. It includes three complementary biological concepts: Mode_of_Inheritance (MI), ONset_and_clinical_course (ON), and Phenotypic_Abnormality (PA).
- Mouse Phenotype (MP) Ontology (MP) MP describes phenotypes of the mouse after a specific gene is genetically disrupted. Using it, Mouse Genome Informatics (MGI) provides high-coverate gene-level phenotypes for the mouse.
- Worm Phenotype (WP) Ontology (WP) WP classifies and organizes phenotype descriptions for C. elegans and other nematodes. Using it, WormBase provides primary resource for phenotype annotations for C. elegans.
- Yeast Phenotype (YP) Ontology (YP) Based on YP which is the major contributor to the ‘Ascomycete phenotype ontology’, Saccharomyces Genome Database (SGD) provides single mutant phenotypes for every gene in the yeast genome.
- Fly Phenotype (FP) Ontology (FP) FP refers to FlyBase controlled vocabulary. Specifically, a structured controlled vocabulary is used for the annotation of alleles (for their mutagen etc) in FlyBase.
- Fly Anatomy (FA) Ontology (FA) FA is a structured controlled vocabulary of the anatomy of Drosophila melanogaster, used for the description of phenotypes and where a gene is expressed.
- Zebrafish Anatomy (ZA) Ontology (ZA) ZA displays anatomical terms of the zebrafish using standard anatomical nomenclature, together with affected genes.
- Xenopus Anatomy (XA) Ontology (XA) XA represents the lineage of tissues and the timing of development for frogs (Xenopus laevis and Xenopus tropicalis). It is used to annotate Xenopus gene expression patterns and mutant and morphant phenotypes.
- Arabidopsis Plant Ontology (AP) Ontology (AP) As a major contributor to Plant Ontology which describes plant anatomical and morphological structures (AN) and growth and developmental stages (DE), the Arabidopsis Information Resource (TAIR) provides arabidopsis plant ontology annotations for the model higher plant Arabidopsis thaliana.
- Enzyme Commission (EC) Ontology (EC) Each enzyme is allocated a four-digit EC number, the first three digits of which define the reaction catalysed and the fourth of which is a unique identifier (serial number). Each enzyme is also assigned a systematic name that uniquely defines the reaction catalysed.
- DrugBank ATC (DB) Ontology (DB) In the Anatomical Therapeutic Chemical (ATC) classification system, drugs are classified in groups at five different levels according to the organ or system (1st level, anatomical main group) on which they act and their therapeutic (2nd level, therapeutic subgroup), pharmacological (3rd level, pharmacological subgroup) and chemical properties (4th level, chemical subgroup; 5th level, chemical substance). Only drugs in DrugBank are considered.
- UniProtKB KeyWords (KW) Ontology (KW) Keywords in UniProtKB are controlled vocabulary, providing a summary of the entry content and are used to index UniProtKB/Swiss-Prot entries based on 10 categories (the category "Technical term" being excluded here). Each keyword is attributed manually to UniProtKB/Swiss-Prot entries and automatically to UniProtKB/TrEMBL entries (according to specific annotation rules).
- UniProtKB UniPathway (UP) Ontology (UP) UP is a fully manually curated resource for the representation and annotation of metabolic pathways, being used as controlled vocabulary for pathway annotation in UniProtKB.
Structural Domain Phenotype Ontology and its Annotations
Structural Classification of Proteins (SCOP) classifies evolutionary-related domains into Superfamily level and Family level. Using the phenotype ontologies above, we have generated the domain-centric phenotype annotations, and further identified those phenotype terms which are the most informative to annotate SCOP domains. Promisingly, domain-centric phenotypic annotations can serve as an alternative starting point to explore genotype-phenotype relationships. We provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.
- Structural Domain Disease Ontology (DO) Ontology (SDDO) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DO.txt, and the corresponding ontology:SDDO.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Human Phenotype (HP) Ontology (SDHP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2HP.txt, and the corresponding ontology:SDHP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Mouse Phenotype (MP) Ontology (SDMP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2MP.txt, and the corresponding ontology:SDMP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Worm Phenotype (WP) Ontology (SDWP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2WP.txt, and the corresponding ontology:SDWP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Yeast Phenotype (YP) Ontology (SDYP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2YP.txt, and the corresponding ontology:SDYP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Fly Phenotype (FP) Ontology (SDFP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FP.txt, and the corresponding ontology:SDFP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Fly Anatomy (FA) Ontology (SDFA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FA.txt, and the corresponding ontology:SDFA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Zebrafish Anatomy (ZA) Ontology (SDZA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2ZA.txt, and the corresponding ontology:SDZA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Xenopus Anatomy (XA) Ontology (SDXA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2XA.txt, and the corresponding ontology:SDXA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Arabidopsis Plant Ontology (AP) Ontology (SDAP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2AP.txt, and the corresponding ontology:SDAP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Enzyme Commission (EC) Ontology (SDEC) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2EC.txt, and the corresponding ontology:SDEC.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain DrugBank ATC (DB) Ontology (SDDB) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DB.txt, and the corresponding ontology:SDDB.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain UniProtKB KeyWords (KW) Ontology (SDKW) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2KW.txt, and the corresponding ontology:SDKW.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain UniProtKB UniPathway (UP) Ontology (SDUP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2UP.txt, and the corresponding ontology:SDUP.txt) and mysql tables (Domain2PO.sql.gz).
Supra-domain Phenotype Ontology and its Annotations
Although domain-centric annotations hold great promise in describing phenotypic nature of independent domains, most domains themselves may not just work alone. In multi-domain proteins, they may be combined together to form distinct domain architectures. The recombination of the existing domains is considered as one of major driving forces for phenotypic diversificaation. As an extension, we have also generated supra-domain phenotype ontology and its annotations. Compared to domain-centric phenotype ontology and annotations (SCOP domains at the Superfamily level and Family level), this version focuses on supra-domains and individual SCOP domains ONLY at the Superfamily level. Besides, in terms of individual superfamilies, their annotations from the domain-centric version may be different from those from supra-domains version. Depending on your focus, the former should be used for the consideration of both the Superfamily level and Family level, otherwise the latter should be used if you are interested in domain combinations. Also, we provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.
- Supra-domain Domain Disease Ontology (DO) Ontology (SPDO) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DO.txt, and the corresponding ontology:SPDO.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Human Phenotype (HP) Ontology (SPHP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2HP.txt, and the corresponding ontology:SPHP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Mouse Phenotype (MP) Ontology (SPMP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2MP.txt, and the corresponding ontology:SPMP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Worm Phenotype (WP) Ontology (SPWP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2WP.txt, and the corresponding ontology:SPWP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Yeast Phenotype (YP) Ontology (SPYP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2YP.txt, and the corresponding ontology:SPYP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Fly Phenotype (FP) Ontology (SPFP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FP.txt, and the corresponding ontology:SPFP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Fly Anatomy (FA) Ontology (SPFA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FA.txt, and the corresponding ontology:SPFA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Zebrafish Anatomy (ZA) Ontology (SPZA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2ZA.txt, and the corresponding ontology:SPZA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Xenopus Anatomy (XA) Ontology (SPXA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2XA.txt, and the corresponding ontology:SPXA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Arabidopsis Plant Ontology (AP) Ontology (SPAP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2AP.txt, and the corresponding ontology:SPAP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Enzyme Commission (EC) Ontology (SPEC) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2EC.txt, and the corresponding ontology:SPEC.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain DrugBank ATC (DB) Ontology (SPDB) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DB.txt, and the corresponding ontology:SPDB.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain UniProtKB KeyWords (KW) Ontology (SPKW) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2KW.txt, and the corresponding ontology:SPKW.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain UniProtKB UniPathway (UP) Ontology (SPUP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2UP.txt, and the corresponding ontology:SPUP.txt) and mysql tables (SP2PO.sql.gz).
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Superfamily(show details)
Superfamily domains annotated to this WP term (Not in SDWP)
Highlighted in gray are those with FDR_all>0.001
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| Tim10-like | 0 | DIRECT |
| Cation efflux protein cytoplasmic domain-like | 0 | DIRECT |
| ArfGap/RecO-like zinc finger | 0 | DIRECT |
| Phosphoglucomutase, first 3 domains | 0 | DIRECT |
| 2Fe-2S ferredoxin-like | 0 | DIRECT |
| Integrin alpha N-terminal domain | 0 | DIRECT |
| MIR domain | 0 | DIRECT |
| Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
| Subtilisin-like | 0 | DIRECT |
| TK C-terminal domain-like | 0 | DIRECT |
| Galactose oxidase, central domain | 0 | DIRECT |
| DEATH domain | 0 | DIRECT |
| CRAL/TRIO N-terminal domain | 0 | DIRECT |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
| Rap/Ran-GAP | 0 | DIRECT |
| SAND domain-like | 0 | DIRECT |
| cAMP-binding domain-like | 0 | DIRECT |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | DIRECT |
| Integrin domains | 0 | DIRECT |
| Bactericidal permeability-increasing protein, BPI | 0 | DIRECT |
| Clathrin adaptor appendage domain | 0 | DIRECT |
| Helical domain of Sec23/24 | 0 | DIRECT |
| LDH C-terminal domain-like | 0 | DIRECT |
| Transducin (alpha subunit), insertion domain | 0 | DIRECT |
| Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | DIRECT |
| Cadherin-like | 0 | DIRECT |
| PEP carboxykinase-like | 0 | DIRECT |
| Hypothetical protein c14orf129, hspc210 | 0 | DIRECT |
| BEACH domain | 0 | DIRECT |
| L-aspartase-like | 0 | DIRECT |
| Class I glutamine amidotransferase-like | 0 | DIRECT |
| SCP-like | 0 | DIRECT |
| Oxysterol-binding protein-like | 0 | DIRECT |
| GroEL-intermediate domain like | 0 | DIRECT |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Cystatin/monellin | 0 | DIRECT |
| SAICAR synthase-like | 0 | DIRECT |
| Formate/glycerate dehydrogenase catalytic domain-like | 0 | DIRECT |
| Tubby C-terminal domain-like | 0 | DIRECT |
| Carbohydrate phosphatase | 0 | DIRECT |
| Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | DIRECT |
| Heme-dependent catalase-like | 0 | DIRECT |
| SMAD/FHA domain | 0 | DIRECT |
| Activating enzymes of the ubiquitin-like proteins | 0 | DIRECT |
| SMAD MH1 domain | 0 | DIRECT |
| Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
| Acid phosphatase/Vanadium-dependent haloperoxidase | 0 | DIRECT |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0 | DIRECT |
| Thiamin diphosphate-binding fold (THDP-binding) | 0 | DIRECT |
| Pepsin inhibitor-3 | 0 | DIRECT |
| WGR domain-like | 0 | DIRECT |
| Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | DIRECT |
| DNA ligase/mRNA capping enzyme, catalytic domain | 0 | DIRECT |
| ADP-ribosylation | 0 | DIRECT |
| Subdomain of clathrin and coatomer appendage domain | 0 | DIRECT |
| ARID-like | 0 | DIRECT |
| Protease propeptides/inhibitors | 0 | DIRECT |
| Proton glutamate symport protein | 0 | DIRECT |
| Intermediate filament protein, coiled coil region | 0 | DIRECT |
| Ferritin-like | 0 | DIRECT |
| Second domain of FERM | 0 | DIRECT |
| Ribokinase-like | 0 | DIRECT |
| ValRS/IleRS/LeuRS editing domain | 0 | DIRECT |
| Spectrin repeat | 0 | DIRECT |
| Heme-dependent peroxidases | 0 | DIRECT |
| GYF domain | 0 | DIRECT |
| S-adenosylmethionine synthetase | 0 | DIRECT |
| PHM/PNGase F | 0 | DIRECT |
| Zn-binding ribosomal proteins | 0 | DIRECT |
| PABC (PABP) domain | 0 | DIRECT |
| LEM domain | 0 | DIRECT |
| KA1-like | 0 | DIRECT |
| YWTD domain | 0 | DIRECT |
| Alpha-L RNA-binding motif | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
| Hect, E3 ligase catalytic domain | 0 | DIRECT |
| PLC-like phosphodiesterases | 0 | DIRECT |
| Sec1/munc18-like (SM) proteins | 0 | DIRECT |
| GroEL apical domain-like | 0 | DIRECT |
| ALDH-like | 0 | DIRECT |
| Surp module (SWAP domain) | 0 | DIRECT |
| MgtE membrane domain-like | 0 | DIRECT |
| Class II aaRS ABD-related | 0 | DIRECT |
| L30e-like | 0 | DIRECT |
| PEBP-like | 0 | DIRECT |
| Seven-hairpin glycosidases | 0 | DIRECT |
| Small-conductance potassium channel | 0 | DIRECT |
| PEP carboxykinase N-terminal domain | 0 | DIRECT |
| beta-lactamase/transpeptidase-like | 0 | DIRECT |
| JAB1/MPN domain | 0 | DIRECT |
| Retrovirus zinc finger-like domains | 0 | DIRECT |
| Smc hinge domain | 0 | DIRECT |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
| Ribosomal protein L10-like | 0 | DIRECT |
| Elafin-like | 0 | DIRECT |
| GHMP Kinase, C-terminal domain | 0 | DIRECT |
| Tricorn protease domain 2 | 0 | DIRECT |
| Terpenoid cyclases/Protein prenyltransferases | 0 | DIRECT |
| Tudor/PWWP/MBT | 0 | DIRECT |
| Mitochondrial carrier | 0 | DIRECT |
| Profilin (actin-binding protein) | 0 | DIRECT |
| Riboflavin synthase domain-like | 0 | DIRECT |
| Sec7 domain | 0 | DIRECT |
| MFPT repeat-like | 0 | DIRECT |
| Bacterial exopeptidase dimerisation domain | 0 | DIRECT |
| Nucleoporin domain | 0 | DIRECT |
| Carbon-nitrogen hydrolase | 0 | DIRECT |
| Flavoproteins | 0 | DIRECT |
| SPOC domain-like | 0 | DIRECT |
| 3-carboxy-cis,cis-mucoante lactonizing enzyme | 0 | DIRECT |
| Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | DIRECT |
| Pentein | 0 | DIRECT |
| Lamin A/C globular tail domain | 0 | DIRECT |
| PYP-like sensor domain (PAS domain) | 0 | DIRECT |
| Glycolipid transfer protein, GLTP | 0 | DIRECT |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
| Type II DNA topoisomerase | 0 | DIRECT |
| Restriction endonuclease-like | 0 | DIRECT |
| dsRNA-binding domain-like | 0 | DIRECT |
| Troponin coil-coiled subunits | 0 | DIRECT |
| Transducin (heterotrimeric G protein), gamma chain | 0 | DIRECT |
| Zn-finger domain of Sec23/24 | 0 | DIRECT |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
| Clc chloride channel | 0 | DIRECT |
| DNA repair protein MutS, domain III | 0 | DIRECT |
| GAT-like domain | 0 | DIRECT |
| Ribosomal proteins S24e, L23 and L15e | 0 | DIRECT |
| Cullin homology domain | 0 | DIRECT |
| ThrRS/AlaRS common domain | 0 | DIRECT |
| ENTH/VHS domain | 0 | DIRECT |
| Alkaline phosphatase-like | 0 | DIRECT |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Hormone receptor domain | 0 | DIRECT |
| Fibrinogen C-terminal domain-like | 0 | DIRECT |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
| lambda repressor-like DNA-binding domains | 0 | DIRECT |
| Nop domain | 0 | DIRECT |
| HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
| PAP/OAS1 substrate-binding domain | 0 | DIRECT |
| YbiA-like | 0 | DIRECT |
| Periplasmic binding protein-like II | 0 | DIRECT |
| Carboxypeptidase regulatory domain-like | 0 | DIRECT |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | DIRECT |
| SIS domain | 0 | DIRECT |
| Skp1 dimerisation domain-like | 0 | DIRECT |
| GroEL equatorial domain-like | 0 | DIRECT |
| Aminoacid dehydrogenase-like, N-terminal domain | 0 | DIRECT |
| PGBD-like | 0 | DIRECT |
| Ran binding protein zinc finger-like | 0 | DIRECT |
| FtsH protease domain-like | 0 | DIRECT |
| Translational machinery components | 0 | DIRECT |
| F1F0 ATP synthase subunit C | 0 | DIRECT |
| Blood coagulation inhibitor (disintegrin) | 0 | DIRECT |
| ISP domain | 0 | DIRECT |
| Thyroglobulin type-1 domain | 0 | DIRECT |
| PK beta-barrel domain-like | 0 | DIRECT |
| Chitinase insertion domain | 0 | DIRECT |
| DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
| Cdc48 domain 2-like | 0 | DIRECT |
| Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0 | DIRECT |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | DIRECT |
| Arginase/deacetylase | 0 | DIRECT |
| R3H domain | 0 | DIRECT |
| TGS-like | 0 | DIRECT |
| Aquaporin-like | 0 | DIRECT |
| eIF4e-like | 0 | DIRECT |
| Cytochrome c | 0 | DIRECT |
| Sec63 N-terminal domain-like | 0 | DIRECT |
| Cu,Zn superoxide dismutase-like | 0 | DIRECT |
| FF domain | 0 | DIRECT |
| Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | DIRECT |
| Ribosomal protein S10 | 0 | DIRECT |
| Succinyl-CoA synthetase domains | 0 | DIRECT |
| Doublecortin (DC) | 0 | DIRECT |
| Polo-box domain | 0 | DIRECT |
| Phosphoenolpyruvate/pyruvate domain | 0 | DIRECT |
| Calpain large subunit, middle domain (domain III) | 0 | DIRECT |
| Citrate synthase | 0 | DIRECT |
| CAD & PB1 domains | 0 | DIRECT |
| MOSC N-terminal domain-like | 0 | DIRECT |
| Domain of poly(ADP-ribose) polymerase | 0 | DIRECT |
| FAD-dependent thiol oxidase | 0 | DIRECT |
| Annexin | 0 | DIRECT |
| Nucleotidyltransferase | 0 | DIRECT |
| Cullin repeat-like | 0 | DIRECT |
| Hedgehog/intein (Hint) domain | 0 | DIRECT |
| P-loop containing nucleoside triphosphate hydrolases | 2.175e-05 | DIRECT |
| Protein kinase-like (PK-like) | 0.0004473 | DIRECT |
| WD40 repeat-like | 0.002502 | INHERITED FROM: protein aggregation variant || protein protein interaction variant || organism metabolism processing variant || protein aggregation induced paralysis || late larval arrest |
| PapD-like | 0.002663 | INHERITED FROM: fat content variant || developmental growth variant || lipid metabolism variant || larval arrest || growth variant || larval growth variant || slow growth |
| Histone-fold | 0.002663 | INHERITED FROM: stress induced lethality increased || pathogen susceptibility increased || organism osmotic stress response variant || organism hypertonic lethality increased || stress induced lethality variant |
| PH domain-like | 0.002703 | INHERITED FROM: organism metabolism processing variant || growth rate variant || copper response variant || organism environmental stimulus response variant || drug induced gene expression variant || transgene subcellular localization variant || protein phosphorylation variant || protein expression variant |
| PDZ domain-like | 0.00929 | INHERITED FROM: drug response variant |
| Periplasmic binding protein-like I | 0.01053 | INHERITED FROM: osmotic avoidance defective || bromide chemotaxis defective || fat content variant || metabolic pathway variant || second messenger mediated signaling variant || iodide chemotaxis variant || positive chemotaxis defective || AWC odorant chemotaxis variant || carbon dioxide avoidance variant || chemotaxis variant || organism environmental stimulus response variant || bromide chemotaxis variant || memory retention defective || iodide chemotaxis defective || magnesium chemotaxis defective || lithium chemotaxis defective || chemical response variant || chemosensory response variant |
| TPR-like | 0.01527 | INHERITED FROM: associative learning variant || light body touch resistant || positive chemotaxis defective || ammonium chloride chemotaxis variant || chemotaxis variant || dauer arrest variant || pattern of transgene expression variant |
| Actin-like ATPase domain | 0.02185 | INHERITED FROM: pathogen susceptibility increased || protein interaction variant || transgene expression variant || protein aggregation variant || protein protein interaction variant || organism metabolism processing variant || cadmium hypersensitive || cadmium response variant |
| "Winged helix" DNA-binding domain | 0.04514 | INHERITED FROM: gene expression variant || germline transgene silencing variant || protein aggregation variant || protein protein interaction variant || organism metabolism processing variant || shortened life span || organism hypertonic lethality increased || paraquat hypersensitive || life span variant || spontaneous mutation rate increased || protein expression increased |
| SH2 domain | 0.05073 | INHERITED FROM: aldicarb resistant || acetylcholinesterase inhibitor resistant |
| Homeodomain-like | 0.06307 | INHERITED FROM: carbon dioxide response variant || growth rate variant || imipramine resistant || carbon dioxide avoidance variant || inhibitor of serotonin uptake variant || adrenergic receptor antagonist response variant || egg laying imipramine resistant || ectopic expression transgene || sexually dimorphic physiology variant || touch resistant |
| ARM repeat | 0.07032 | INHERITED FROM: gene expression variant || RNAi response variant || organism metabolism processing variant || sick || protein expression variant |
| PAZ domain | 0.08182 | INHERITED FROM: somatic transgene silencing variant || gene expression variant || RNAi response variant || maintenance of gene silencing variant || mRNA levels increased || organism metabolism processing variant || siRNA expression variant || RNA expression variant || 21U RNA expression variant |
| HLH, helix-loop-helix DNA-binding domain | 0.08256 | INHERITED FROM: aqueous positive chemotaxis variant || aqueous positive chemotaxis defective || chemotaxis variant || lysine chemotaxis defective || gene expression level reduced || ectopic expression transgene |
| HSP20-like chaperones | 0.1036 | INHERITED FROM: pathogen susceptibility increased || protein interaction variant || transgene expression variant || protein aggregation variant || protein protein interaction variant || organism metabolism processing variant || cadmium hypersensitive || metal response variant || pattern of transgene expression variant || transgene subcellular localization variant || cadmium response variant || life span variant |
| CCCH zinc finger | 0.1036 | INHERITED FROM: transgene expression undetectable || ectopic expression transgene |
| Nucleic acid-binding proteins | 0.1071 | INHERITED FROM: hydroxyurea hypersensitive || hydroxyurea response variant || sick |
| Calcium ATPase, transmembrane domain M | 0.1164 | INHERITED FROM: lipid composition variant || drug hypersensitive || nicotine hypersensitive |
| Translation proteins | 0.1164 | INHERITED FROM: gene expression variant || protein phosphorylation increased || transgene expression variant || mRNA levels increased || mRNA levels reduced || protein aggregation variant || protein protein interaction variant || organism metabolism processing variant || extended life span || protein expression reduced || mRNA expression variant || protein phosphorylation variant || sick || protein modification variant || organism oxidative stress response variant |
| RNI-like | 0.1217 | INHERITED FROM: resistant to protein aggregation induced paralysis || protein aggregation induced paralysis |
| Ankyrin repeat | 0.1291 | INHERITED FROM: organism stress response variant || organism heat response variant || odorant negative chemotaxis defective || chemotaxis variant || octanol chemotaxis defective || octanol chemotaxis variant || chemosensory response variant |
| Metal cation-transporting ATPase, ATP-binding domain N | 0.1308 | INHERITED FROM: lipid composition variant || drug hypersensitive || nicotine hypersensitive |
| Chromo domain-like | 0.1308 | INHERITED FROM: germline transgene silencing variant || maintenance of gene silencing variant || organism UV response variant || organism UV hypersensitive || ectopic expression transgene |
| EGF/Laminin | 0.1423 | INHERITED FROM: odorant negative chemotaxis defective || octanol chemotaxis defective || protein expression reduced || negative chemotaxis variant || octanol chemotaxis variant |
| Calcium ATPase, transduction domain A | 0.1469 | INHERITED FROM: organism environmental stimulus response variant || drug hypersensitive || nicotine hypersensitive |
| Quinoprotein alcohol dehydrogenase-like | 0.1648 | INHERITED FROM: L2 arrest || mid larval arrest || early larval arrest || fat content increased |
| RNA-binding domain, RBD | 0.177 | INHERITED FROM: RNA processing variant || maintenance of gene silencing variant || organism metabolism processing variant || mRNA export variant || RNA expression variant || sick || late larval arrest |
| WW domain | 0.1846 | INHERITED FROM: gene expression variant || aldicarb resistant || acetylcholinesterase inhibitor resistant |
| Tubulin C-terminal domain-like | 0.1846 | INHERITED FROM: gene expression variant || protein interaction variant || transgene expression variant || protein aggregation variant || mechanosensation variant || nicotine response variant || protein protein interaction variant || organism metabolism processing variant || transgene subcellular localization variant || miRNA expression variant || touch resistant |
| NAD(P)-binding Rossmann-fold domains | 0.1878 | INHERITED FROM: pheromone induced dauer formation variant |
| Multidrug resistance efflux transporter EmrE | 0.2069 | INHERITED FROM: pathogen resistance increased || bacterially unswollen || organism pathogen response variant |
| Tubulin nucleotide-binding domain-like | 0.2069 | INHERITED FROM: gene expression variant || protein interaction variant || transgene expression variant || protein aggregation variant || mechanosensation variant || nicotine response variant || protein protein interaction variant || organism metabolism processing variant || organism environmental stimulus response variant || transgene subcellular localization variant || miRNA expression variant || touch resistant |
| Acid proteases | 0.2069 | INHERITED FROM: gene expression variant || protein interaction variant || transgene expression variant || protein aggregation variant || protein protein interaction variant || organism metabolism processing variant || hypoosmotic shock hypersensitive || pattern of transgene expression variant || transgene subcellular localization variant || osmotic integrity variant |
| Nicotinic receptor ligand binding domain-like | 0.2261 | INHERITED FROM: positive chemotaxis variant || aqueous chemosensory response variant || cholinergic agonist resistant || antihelmintic response variant || nicotine resistant || mechanosensation variant || enhanced taste aversion defective || hypoosmotic shock hypersensitive || organism environmental stimulus response variant || sodium chloride chemotaxis variant || chemical response variant || DMPP response variant |
| Nucleotide cyclase | 0.2293 | INHERITED FROM: positive chemotaxis variant || carbon dioxide response variant || bromide chemotaxis defective || anion positive chemotaxis variant || metabolic pathway variant || second messenger mediated signaling variant || iodide chemotaxis variant || AWC odorant chemotaxis variant || anion positive chemotaxis defective || cation positive chemotaxis defective || chemotaxis variant || organism environmental stimulus response variant || cation positive chemotaxis variant || bromide chemotaxis variant || iodide chemotaxis defective || magnesium chemotaxis defective || lithium chemotaxis defective || chemosensory response variant |
| POZ domain | 0.2459 | INHERITED FROM: L1 arrest || resistant to protein aggregation induced paralysis || protein aggregation induced paralysis || early larval arrest |
| ABC transporter transmembrane region | 0.2474 | INHERITED FROM: RNAi response variant || cadmium hypersensitive || metal response variant || cadmium response variant |
| Cyclin-like | 0.2515 | INHERITED FROM: protein phosphorylation reduced || protein phosphorylation variant |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.2558 | INHERITED FROM: positive chemotaxis variant || aqueous chemosensory response variant || cholinergic agonist resistant || antihelmintic response variant || nicotine resistant || mechanosensation variant || enhanced taste aversion defective || hypoosmotic shock hypersensitive || organism environmental stimulus response variant || sodium chloride chemotaxis variant || chemical response variant || DMPP response variant |
| Bromodomain | 0.2598 | INHERITED FROM: organism stress response variant || organism UV response variant || sick || organism UV hypersensitive |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0.2708 | INHERITED FROM: antimicrobial gene expression variant || aldicarb resistant || growth rate variant || organism environmental stimulus response variant || protein subcellular localization variant || drug induced gene expression variant || organism pathogen response variant || protein expression variant |
| Growth factor receptor domain | 0.2742 | INHERITED FROM: dauer arrest variant |
| SNARE-like | 0.2908 | INHERITED FROM: aldicarb resistant || transgene expression variant || acetylcholinesterase inhibitor resistant || pattern of transgene expression variant || transgene subcellular localization variant || acetylcholinesterase inhibitor response variant || sick |
| Band 7/SPFH domain | 0.2908 | INHERITED FROM: mechanosensation variant || organism environmental stimulus response variant |
| FYVE/PHD zinc finger | 0.3214 | INHERITED FROM: protein methylation variant || organism UV hypersensitive || ectopic expression transgene |
| Translation proteins SH3-like domain | 0.3244 | INHERITED FROM: gene expression variant || transgene expression variant || protein aggregation variant || protein protein interaction variant || organism metabolism processing variant |
| Multidrug efflux transporter AcrB transmembrane domain | 0.3536 | INHERITED FROM: odorant chemosensory response variant || negative chemotaxis variant || embryo osmotic integrity defective early emb |
| Voltage-gated potassium channels | 0.3577 | INHERITED FROM: mechanosensation variant || positive chemotaxis defective || growth rate variant || adrenergic receptor antagonist response variant |
| Cation efflux protein transmembrane domain-like | 0.3626 | INHERITED FROM: cadmium hypersensitive || metal response variant |
| Tropomyosin | 0.3626 | INHERITED FROM: drug resistant |
| Cysteine-rich domain | 0.4036 | INHERITED FROM: positive chemotaxis variant || antimicrobial gene expression variant || odorant chemosensory response variant || organism metabolism processing variant || odorant positive chemotaxis variant || chemotaxis variant || organism environmental stimulus response variant || protein subcellular localization variant || drug induced gene expression variant || transgene subcellular localization variant || organism pathogen response variant |
| Ribosomal protein S5 domain 2-like | 0.4036 | INHERITED FROM: early larval arrest |
| Cysteine proteinases | 0.4044 | INHERITED FROM: protein interaction variant || transgene expression variant || protein aggregation variant || protein protein interaction variant || organism metabolism processing variant || hypoosmotic shock hypersensitive || pattern of transgene expression variant || transgene subcellular localization variant || osmotic integrity variant |
| Regulator of G-protein signaling, RGS | 0.4125 | INHERITED FROM: mechanosensation variant |
| DNase I-like | 0.4504 | INHERITED FROM: protein subcellular localization variant || pattern protein expression variant |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0.4504 | INHERITED FROM: pathogen susceptibility increased || gene expression variant || protein interaction variant || transgene expression variant || protein aggregation variant || protein protein interaction variant || organism metabolism processing variant || cadmium hypersensitive || metal response variant || organism environmental stimulus response variant || pattern of transgene expression variant || transgene subcellular localization variant || cadmium response variant || life span variant || transgene expression increased |
| Myosin rod fragments | 0.4504 | INHERITED FROM: drug resistant |
| HAD-like | 0.4628 | INHERITED FROM: lipid composition variant || nicotine hypersensitive |
| Sm-like ribonucleoproteins | 0.4781 | INHERITED FROM: transgene expression variant || pattern of transgene expression variant || protein subcellular localization variant || sick || protein expression variant |
| FKBP-like | 0.484 | INHERITED FROM: gene expression variant || protein interaction variant || transgene expression variant || protein aggregation variant || protein protein interaction variant || organism metabolism processing variant || pattern of transgene expression variant || transgene subcellular localization variant |
| Ligand-binding domain in the NO signalling and Golgi transport | 0.4973 | INHERITED FROM: carbon dioxide response variant || carbon dioxide avoidance variant || organism environmental stimulus response variant |
| HMG-box | 0.5141 | INHERITED FROM: maintenance of gene silencing variant |
| Cytochrome P450 | 0.538 | INHERITED FROM: cadmium hypersensitive || metal response variant || cadmium response variant |
| Ubiquitin-like | 0.5481 | INHERITED FROM: protein interaction variant || protein aggregation variant || protein protein interaction variant || hypersensitive to protein aggregation induced paralysis |
| Cystine-knot cytokines | 0.5517 | INHERITED FROM: levamisole response variant || nicotine response variant || transgene expression reduced |
| Lipocalins | 0.5739 | INHERITED FROM: fat content variant || lipid metabolism variant || fat content increased |
| SAM/Pointed domain | 0.5823 | INHERITED FROM: aldicarb resistant || drug resistant |
| Chaperone J-domain | 0.59 | INHERITED FROM: gene expression variant || protein interaction variant || transgene expression variant || protein aggregation variant || protein protein interaction variant || organism metabolism processing variant || pattern of transgene expression variant |
| PRTase-like | 0.611 | INHERITED FROM: Fluorouracil resistant || drug response variant || drug resistant |
| Osmotin, thaumatin-like protein | 0.611 | INHERITED FROM: cadmium hypersensitive || metal response variant || level of transgene expression variant || cadmium response variant || transgene expression reduced |
| Metallo-dependent phosphatases | 0.6211 | INHERITED FROM: antibody staining variant |
| MFS general substrate transporter | 0.63 | INHERITED FROM: organism high sodium chloride hypersensitive |
| Ribonuclease H-like | 0.6449 | INHERITED FROM: somatic transgene silencing variant || RNAi response variant || maintenance of gene silencing variant || siRNA expression variant || RNA expression variant || 21U RNA expression variant |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0.6771 | INHERITED FROM: life span variant |
| (Trans)glycosidases | 0.6771 | INHERITED FROM: pathogen susceptibility increased || pathogen load variant || transgene expression reduced |
| Lipovitellin-phosvitin complex, superhelical domain | 0.6771 | INHERITED FROM: life span variant |
| Frizzled cysteine-rich domain | 0.6771 | INHERITED FROM: protein expression variant |
| GST C-terminal domain-like | 0.6776 | INHERITED FROM: organism electrophilic stress hypersensitive || enzyme activity variant || organism stress response variant || organism metabolism processing variant || cadmium hypersensitive || metal response variant || organism environmental stimulus response variant || cadmium response variant || enzyme activity reduced |
| SET domain | 0.7012 | INHERITED FROM: somatic transgene silencing variant || RNAi response variant || maintenance of gene silencing variant || antibody staining variant || mRNA levels reduced || protein methylation variant || protein modification variant || spontaneous mutation rate increased || ectopic expression antibody || ectopic expression transgene |
| Class II aaRS and biotin synthetases | 0.7063 | INHERITED FROM: gene expression variant || transgene expression variant || organism metabolism processing variant || transgene expression increased |
| Fibronectin type III | 0.7232 | INHERITED FROM: growth rate variant || organism temperature response variant |
| Galactose-binding domain-like | 0.7261 | INHERITED FROM: protein interaction variant || protein aggregation variant || protein protein interaction variant || transgene subcellular localization variant |
| MIT domain | 0.748 | INHERITED FROM: protein interaction variant || protein aggregation variant || protein protein interaction variant || transgene subcellular localization variant |
| beta-sandwich domain of Sec23/24 | 0.748 | INHERITED FROM: transgene subcellular localization variant |
| ADC-like | 0.748 | INHERITED FROM: protein interaction variant || protein aggregation variant || protein protein interaction variant || transgene subcellular localization variant |
| 5' to 3' exonuclease, C-terminal subdomain | 0.748 | INHERITED FROM: organism stress response variant |
| Acyl-CoA N-acyltransferases (Nat) | 0.7487 | INHERITED FROM: ectopic expression transgene |
| SH3-domain | 0.7747 | INHERITED FROM: protein expression variant |
| UBC-like | 0.7964 | INHERITED FROM: gene expression variant || protein interaction variant || transgene expression variant || protein aggregation variant || protein protein interaction variant || organism metabolism processing variant || pattern of transgene expression variant || transgene subcellular localization variant |
| Nucleotidylyl transferase | 0.8178 | INHERITED FROM: paraquat resistant || paraquat response variant || pesticide response variant |
| Rhodanese/Cell cycle control phosphatase | 0.8359 | INHERITED FROM: pathogen susceptibility increased |
| alpha/beta-Hydrolases | 0.861 | INHERITED FROM: acetylcholinesterase activity variant || acetylcholinesterase reduced |
| Insulin-like | 0.8735 | INHERITED FROM: fat content variant || lipid metabolism variant || dauer arrest variant || organism environmental stimulus response variant |
| Immunoglobulin | 0.8782 | INHERITED FROM: growth rate variant || drug response variant |
| PIN domain-like | 0.8841 | INHERITED FROM: organism stress response variant |
| p53-like transcription factors | 0.8855 | INHERITED FROM: gene expression level reduced |
| Ribonuclease PH domain 2-like | 0.9265 | INHERITED FROM: early larval arrest |
| Glucocorticoid receptor-like (DNA-binding domain) | 0.9556 | INHERITED FROM: gene expression level high || SDS sensitive dauer || lipid metabolism variant || chemical hypersensitive || transgene expression undetectable cell specific || dauer resistance to harsh conditions variant || fat content increased |
| Cyclophilin-like | 0.9751 | INHERITED FROM: gene expression variant || protein interaction variant || transgene expression variant || protein aggregation variant || protein protein interaction variant || organism metabolism processing variant || pattern of transgene expression variant || transgene subcellular localization variant |
| Bet v1-like | 0.9776 | INHERITED FROM: growth rate variant |
| Thiolase-like | 0.9776 | INHERITED FROM: fat content variant |
| B-box zinc-binding domain | 1 | INHERITED FROM: protein interaction variant || transgene expression variant || protein aggregation variant || protein protein interaction variant || pattern of transgene expression variant || transgene subcellular localization variant |
| RING/U-box | 1 | INHERITED FROM: gene expression variant || protein interaction variant || transgene expression variant || protein aggregation variant || protein protein interaction variant || organism metabolism processing variant || pattern of transgene expression variant || transgene subcellular localization variant |
| Snake toxin-like | 1 | INHERITED FROM: fat content variant || lipid metabolism variant |
| Thioredoxin-like | 1 | INHERITED FROM: organism electrophilic stress hypersensitive || organism heat hypersensitive || enzyme activity variant || organism stress response variant || cadmium hypersensitive || metal response variant || enzyme activity reduced |
| Leucine zipper domain | 1 | INHERITED FROM: mRNA levels reduced || mRNA expression variant |
| Saposin | 1 | INHERITED FROM: transgene expression variant || increased pathogen survival || pathogen load variant || level of transgene expression variant || organism pathogen response variant || transgene expression reduced |
| Nuclear receptor ligand-binding domain | 1 | INHERITED FROM: SDS sensitive dauer || lipid metabolism variant || chemical hypersensitive || dauer resistance to harsh conditions variant || fat content increased |
| F-box domain | 1 | INHERITED FROM: resistant to protein aggregation induced paralysis || protein aggregation induced paralysis |
| Family A G protein-coupled receptor-like | 1 | INHERITED FROM: serotonin induced pumping variant || locomotion rate serotonin variant || organism pathogen response variant || male tail curling serotonin variant || serotonin induced fat reduction variant |
| beta-beta-alpha zinc fingers | 1 | INHERITED FROM: antibody staining reduced || imipramine resistant || inhibitor of serotonin uptake variant || egg laying serotonin resistant || egg laying imipramine resistant |
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| Tim10-like | 0 | Direct |
| Cation efflux protein cytoplasmic domain-like | 0 | Direct |
| ArfGap/RecO-like zinc finger | 0 | Direct |
| Phosphoglucomutase, first 3 domains | 0 | Direct |
| 2Fe-2S ferredoxin-like | 0 | Direct |
| Integrin alpha N-terminal domain | 0 | Direct |
| MIR domain | 0 | Direct |
| Phosphoglucomutase, C-terminal domain | 0 | Direct |
| Subtilisin-like | 0 | Direct |
| TK C-terminal domain-like | 0 | Direct |
| Galactose oxidase, central domain | 0 | Direct |
| DEATH domain | 0 | Direct |
| CRAL/TRIO N-terminal domain | 0 | Direct |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
| Rap/Ran-GAP | 0 | Direct |
| SAND domain-like | 0 | Direct |
| cAMP-binding domain-like | 0 | Direct |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | Direct |
| Integrin domains | 0 | Direct |
| Bactericidal permeability-increasing protein, BPI | 0 | Direct |
| Clathrin adaptor appendage domain | 0 | Direct |
| Helical domain of Sec23/24 | 0 | Direct |
| LDH C-terminal domain-like | 0 | Direct |
| Transducin (alpha subunit), insertion domain | 0 | Direct |
| Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | Direct |
| Cadherin-like | 0 | Direct |
| PEP carboxykinase-like | 0 | Direct |
| Hypothetical protein c14orf129, hspc210 | 0 | Direct |
| BEACH domain | 0 | Direct |
| L-aspartase-like | 0 | Direct |
| Class I glutamine amidotransferase-like | 0 | Direct |
| SCP-like | 0 | Direct |
| Oxysterol-binding protein-like | 0 | Direct |
| GroEL-intermediate domain like | 0 | Direct |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Cystatin/monellin | 0 | Direct |
| SAICAR synthase-like | 0 | Direct |
| Formate/glycerate dehydrogenase catalytic domain-like | 0 | Direct |
| Tubby C-terminal domain-like | 0 | Direct |
| Carbohydrate phosphatase | 0 | Direct |
| Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | Direct |
| Heme-dependent catalase-like | 0 | Direct |
| SMAD/FHA domain | 0 | Direct |
| Activating enzymes of the ubiquitin-like proteins | 0 | Direct |
| SMAD MH1 domain | 0 | Direct |
| Composite domain of metallo-dependent hydrolases | 0 | Direct |
| Acid phosphatase/Vanadium-dependent haloperoxidase | 0 | Direct |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0 | Direct |
| Thiamin diphosphate-binding fold (THDP-binding) | 0 | Direct |
| Pepsin inhibitor-3 | 0 | Direct |
| WGR domain-like | 0 | Direct |
| Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | Direct |
| DNA ligase/mRNA capping enzyme, catalytic domain | 0 | Direct |
| ADP-ribosylation | 0 | Direct |
| Subdomain of clathrin and coatomer appendage domain | 0 | Direct |
| ARID-like | 0 | Direct |
| Protease propeptides/inhibitors | 0 | Direct |
| Proton glutamate symport protein | 0 | Direct |
| Intermediate filament protein, coiled coil region | 0 | Direct |
| Ferritin-like | 0 | Direct |
| Second domain of FERM | 0 | Direct |
| Ribokinase-like | 0 | Direct |
| ValRS/IleRS/LeuRS editing domain | 0 | Direct |
| Spectrin repeat | 0 | Direct |
| Heme-dependent peroxidases | 0 | Direct |
| GYF domain | 0 | Direct |
| S-adenosylmethionine synthetase | 0 | Direct |
| PHM/PNGase F | 0 | Direct |
| Zn-binding ribosomal proteins | 0 | Direct |
| PABC (PABP) domain | 0 | Direct |
| LEM domain | 0 | Direct |
| KA1-like | 0 | Direct |
| YWTD domain | 0 | Direct |
| Alpha-L RNA-binding motif | 0 | Direct |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
| Hect, E3 ligase catalytic domain | 0 | Direct |
| PLC-like phosphodiesterases | 0 | Direct |
| Sec1/munc18-like (SM) proteins | 0 | Direct |
| GroEL apical domain-like | 0 | Direct |
| ALDH-like | 0 | Direct |
| Surp module (SWAP domain) | 0 | Direct |
| MgtE membrane domain-like | 0 | Direct |
| Class II aaRS ABD-related | 0 | Direct |
| L30e-like | 0 | Direct |
| PEBP-like | 0 | Direct |
| Seven-hairpin glycosidases | 0 | Direct |
| Small-conductance potassium channel | 0 | Direct |
| PEP carboxykinase N-terminal domain | 0 | Direct |
| beta-lactamase/transpeptidase-like | 0 | Direct |
| JAB1/MPN domain | 0 | Direct |
| Retrovirus zinc finger-like domains | 0 | Direct |
| Smc hinge domain | 0 | Direct |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | Direct |
| Ribosomal protein L10-like | 0 | Direct |
| Elafin-like | 0 | Direct |
| GHMP Kinase, C-terminal domain | 0 | Direct |
| Tricorn protease domain 2 | 0 | Direct |
| Terpenoid cyclases/Protein prenyltransferases | 0 | Direct |
| Tudor/PWWP/MBT | 0 | Direct |
| Mitochondrial carrier | 0 | Direct |
| Profilin (actin-binding protein) | 0 | Direct |
| Riboflavin synthase domain-like | 0 | Direct |
| Sec7 domain | 0 | Direct |
| MFPT repeat-like | 0 | Direct |
| Bacterial exopeptidase dimerisation domain | 0 | Direct |
| Nucleoporin domain | 0 | Direct |
| Carbon-nitrogen hydrolase | 0 | Direct |
| Flavoproteins | 0 | Direct |
| SPOC domain-like | 0 | Direct |
| 3-carboxy-cis,cis-mucoante lactonizing enzyme | 0 | Direct |
| Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | Direct |
| Pentein | 0 | Direct |
| Lamin A/C globular tail domain | 0 | Direct |
| PYP-like sensor domain (PAS domain) | 0 | Direct |
| Glycolipid transfer protein, GLTP | 0 | Direct |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
| Type II DNA topoisomerase | 0 | Direct |
| Restriction endonuclease-like | 0 | Direct |
| dsRNA-binding domain-like | 0 | Direct |
| Troponin coil-coiled subunits | 0 | Direct |
| Transducin (heterotrimeric G protein), gamma chain | 0 | Direct |
| Zn-finger domain of Sec23/24 | 0 | Direct |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
| Clc chloride channel | 0 | Direct |
| DNA repair protein MutS, domain III | 0 | Direct |
| GAT-like domain | 0 | Direct |
| Ribosomal proteins S24e, L23 and L15e | 0 | Direct |
| Cullin homology domain | 0 | Direct |
| ThrRS/AlaRS common domain | 0 | Direct |
| ENTH/VHS domain | 0 | Direct |
| Alkaline phosphatase-like | 0 | Direct |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Hormone receptor domain | 0 | Direct |
| Fibrinogen C-terminal domain-like | 0 | Direct |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
| lambda repressor-like DNA-binding domains | 0 | Direct |
| Nop domain | 0 | Direct |
| HSP40/DnaJ peptide-binding domain | 0 | Direct |
| PAP/OAS1 substrate-binding domain | 0 | Direct |
| YbiA-like | 0 | Direct |
| Periplasmic binding protein-like II | 0 | Direct |
| Carboxypeptidase regulatory domain-like | 0 | Direct |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | Direct |
| SIS domain | 0 | Direct |
| Skp1 dimerisation domain-like | 0 | Direct |
| GroEL equatorial domain-like | 0 | Direct |
| Aminoacid dehydrogenase-like, N-terminal domain | 0 | Direct |
| PGBD-like | 0 | Direct |
| Ran binding protein zinc finger-like | 0 | Direct |
| FtsH protease domain-like | 0 | Direct |
| Translational machinery components | 0 | Direct |
| F1F0 ATP synthase subunit C | 0 | Direct |
| Blood coagulation inhibitor (disintegrin) | 0 | Direct |
| ISP domain | 0 | Direct |
| Thyroglobulin type-1 domain | 0 | Direct |
| PK beta-barrel domain-like | 0 | Direct |
| Chitinase insertion domain | 0 | Direct |
| DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
| Cdc48 domain 2-like | 0 | Direct |
| Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0 | Direct |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | Direct |
| Arginase/deacetylase | 0 | Direct |
| R3H domain | 0 | Direct |
| TGS-like | 0 | Direct |
| Aquaporin-like | 0 | Direct |
| eIF4e-like | 0 | Direct |
| Cytochrome c | 0 | Direct |
| Sec63 N-terminal domain-like | 0 | Direct |
| Cu,Zn superoxide dismutase-like | 0 | Direct |
| FF domain | 0 | Direct |
| Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | Direct |
| Ribosomal protein S10 | 0 | Direct |
| Succinyl-CoA synthetase domains | 0 | Direct |
| Doublecortin (DC) | 0 | Direct |
| Polo-box domain | 0 | Direct |
| Phosphoenolpyruvate/pyruvate domain | 0 | Direct |
| Calpain large subunit, middle domain (domain III) | 0 | Direct |
| Citrate synthase | 0 | Direct |
| CAD & PB1 domains | 0 | Direct |
| MOSC N-terminal domain-like | 0 | Direct |
| Domain of poly(ADP-ribose) polymerase | 0 | Direct |
| FAD-dependent thiol oxidase | 0 | Direct |
| Annexin | 0 | Direct |
| Nucleotidyltransferase | 0 | Direct |
| Cullin repeat-like | 0 | Direct |
| Hedgehog/intein (Hint) domain | 0 | Direct |
| P-loop containing nucleoside triphosphate hydrolases | 2.175e-05 | Direct |
| Protein kinase-like (PK-like) | 0.0004473 | Direct |
| WD40 repeat-like | 0.002502 | Inherited |
| PapD-like | 0.002663 | Inherited |
| Histone-fold | 0.002663 | Inherited |
| PH domain-like | 0.002703 | Inherited |
| PDZ domain-like | 0.00929 | Inherited |
| Periplasmic binding protein-like I | 0.01053 | Inherited |
| TPR-like | 0.01527 | Inherited |
| Actin-like ATPase domain | 0.02185 | Inherited |
| "Winged helix" DNA-binding domain | 0.04514 | Inherited |
| SH2 domain | 0.05073 | Inherited |
| Homeodomain-like | 0.06307 | Inherited |
| ARM repeat | 0.07032 | Inherited |
| PAZ domain | 0.08182 | Inherited |
| HLH, helix-loop-helix DNA-binding domain | 0.08256 | Inherited |
| HSP20-like chaperones | 0.1036 | Inherited |
| CCCH zinc finger | 0.1036 | Inherited |
| Nucleic acid-binding proteins | 0.1071 | Inherited |
| Calcium ATPase, transmembrane domain M | 0.1164 | Inherited |
| Translation proteins | 0.1164 | Inherited |
| RNI-like | 0.1217 | Inherited |
| Ankyrin repeat | 0.1291 | Inherited |
| Metal cation-transporting ATPase, ATP-binding domain N | 0.1308 | Inherited |
| Chromo domain-like | 0.1308 | Inherited |
| EGF/Laminin | 0.1423 | Inherited |
| Calcium ATPase, transduction domain A | 0.1469 | Inherited |
| Quinoprotein alcohol dehydrogenase-like | 0.1648 | Inherited |
| RNA-binding domain, RBD | 0.177 | Inherited |
| WW domain | 0.1846 | Inherited |
| Tubulin C-terminal domain-like | 0.1846 | Inherited |
| NAD(P)-binding Rossmann-fold domains | 0.1878 | Inherited |
| Multidrug resistance efflux transporter EmrE | 0.2069 | Inherited |
| Tubulin nucleotide-binding domain-like | 0.2069 | Inherited |
| Acid proteases | 0.2069 | Inherited |
| Nicotinic receptor ligand binding domain-like | 0.2261 | Inherited |
| Nucleotide cyclase | 0.2293 | Inherited |
| POZ domain | 0.2459 | Inherited |
| ABC transporter transmembrane region | 0.2474 | Inherited |
| Cyclin-like | 0.2515 | Inherited |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.2558 | Inherited |
| Bromodomain | 0.2598 | Inherited |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0.2708 | Inherited |
| Growth factor receptor domain | 0.2742 | Inherited |
| SNARE-like | 0.2908 | Inherited |
| Band 7/SPFH domain | 0.2908 | Inherited |
| FYVE/PHD zinc finger | 0.3214 | Inherited |
| Translation proteins SH3-like domain | 0.3244 | Inherited |
| Multidrug efflux transporter AcrB transmembrane domain | 0.3536 | Inherited |
| Voltage-gated potassium channels | 0.3577 | Inherited |
| Cation efflux protein transmembrane domain-like | 0.3626 | Inherited |
| Tropomyosin | 0.3626 | Inherited |
| Cysteine-rich domain | 0.4036 | Inherited |
| Ribosomal protein S5 domain 2-like | 0.4036 | Inherited |
| Cysteine proteinases | 0.4044 | Inherited |
| Regulator of G-protein signaling, RGS | 0.4125 | Inherited |
| DNase I-like | 0.4504 | Inherited |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0.4504 | Inherited |
| Myosin rod fragments | 0.4504 | Inherited |
| HAD-like | 0.4628 | Inherited |
| Sm-like ribonucleoproteins | 0.4781 | Inherited |
| FKBP-like | 0.484 | Inherited |
| Ligand-binding domain in the NO signalling and Golgi transport | 0.4973 | Inherited |
| HMG-box | 0.5141 | Inherited |
| Cytochrome P450 | 0.538 | Inherited |
| Ubiquitin-like | 0.5481 | Inherited |
| Cystine-knot cytokines | 0.5517 | Inherited |
| Lipocalins | 0.5739 | Inherited |
| SAM/Pointed domain | 0.5823 | Inherited |
| Chaperone J-domain | 0.59 | Inherited |
| PRTase-like | 0.611 | Inherited |
| Osmotin, thaumatin-like protein | 0.611 | Inherited |
| Metallo-dependent phosphatases | 0.6211 | Inherited |
| MFS general substrate transporter | 0.63 | Inherited |
| Ribonuclease H-like | 0.6449 | Inherited |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0.6771 | Inherited |
| (Trans)glycosidases | 0.6771 | Inherited |
| Lipovitellin-phosvitin complex, superhelical domain | 0.6771 | Inherited |
| Frizzled cysteine-rich domain | 0.6771 | Inherited |
| GST C-terminal domain-like | 0.6776 | Inherited |
| SET domain | 0.7012 | Inherited |
| Class II aaRS and biotin synthetases | 0.7063 | Inherited |
| Fibronectin type III | 0.7232 | Inherited |
| Galactose-binding domain-like | 0.7261 | Inherited |
| MIT domain | 0.748 | Inherited |
| beta-sandwich domain of Sec23/24 | 0.748 | Inherited |
| ADC-like | 0.748 | Inherited |
| 5' to 3' exonuclease, C-terminal subdomain | 0.748 | Inherited |
| Acyl-CoA N-acyltransferases (Nat) | 0.7487 | Inherited |
| SH3-domain | 0.7747 | Inherited |
| UBC-like | 0.7964 | Inherited |
| Nucleotidylyl transferase | 0.8178 | Inherited |
| Rhodanese/Cell cycle control phosphatase | 0.8359 | Inherited |
| alpha/beta-Hydrolases | 0.861 | Inherited |
| Insulin-like | 0.8735 | Inherited |
| Immunoglobulin | 0.8782 | Inherited |
| PIN domain-like | 0.8841 | Inherited |
| p53-like transcription factors | 0.8855 | Inherited |
| Ribonuclease PH domain 2-like | 0.9265 | Inherited |
| Glucocorticoid receptor-like (DNA-binding domain) | 0.9556 | Inherited |
| Cyclophilin-like | 0.9751 | Inherited |
| Bet v1-like | 0.9776 | Inherited |
| Thiolase-like | 0.9776 | Inherited |
| B-box zinc-binding domain | 1 | Inherited |
| RING/U-box | 1 | Inherited |
| Snake toxin-like | 1 | Inherited |
| Thioredoxin-like | 1 | Inherited |
| Leucine zipper domain | 1 | Inherited |
| Saposin | 1 | Inherited |
| Nuclear receptor ligand-binding domain | 1 | Inherited |
| F-box domain | 1 | Inherited |
| Family A G protein-coupled receptor-like | 1 | Inherited |
| beta-beta-alpha zinc fingers | 1 | Inherited |
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Family(show details)
Family domains annotated to this WP term (Not in SDWP)
Highlighted in gray are those with FDR_all>0.001
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| Mammalian PLC | 0 | DIRECT |
| Annexin | 0 | DIRECT |
| Oxysterol-binding protein | 0 | DIRECT |
| Ribokinase-like | 0 | DIRECT |
| Third domain of FERM | 0 | DIRECT |
| Armadillo repeat | 0 | DIRECT |
| Biotin dependent carboxylase carboxyltransferase domain | 0 | DIRECT |
| S-adenosylmethionine synthetase | 0 | DIRECT |
| PABC (PABP) domain | 0 | DIRECT |
| RNA editing terminal uridyl transferase 2, RET2, domain 2 | 0 | DIRECT |
| Cadherin | 0 | DIRECT |
| Clathrin adaptor core protein | 0 | DIRECT |
| Pancreatic carboxypeptidase, activation domain | 0 | DIRECT |
| GAPDH-like | 0 | DIRECT |
| Acyl-CoA thioesterase | 0 | DIRECT |
| Glycerol kinase | 0 | DIRECT |
| Regulator of chromosome condensation RCC1 | 0 | DIRECT |
| Inositol monophosphatase/fructose-1,6-bisphosphatase-like | 0 | DIRECT |
| Surp module (SWAP domain) | 0 | DIRECT |
| Translation initiation factor eIF4e | 0 | DIRECT |
| YbiA-like | 0 | DIRECT |
| Gamma-glutamyltranspeptidase-like | 0 | DIRECT |
| Myeloperoxidase-like | 0 | DIRECT |
| EGF-type module | 0 | DIRECT |
| Sec1/munc18-like (SM) proteins | 0 | DIRECT |
| Phosphoglucomutase, first 3 domains | 0 | DIRECT |
| 1,3-glucuronyltransferase | 0 | DIRECT |
| Protein prenyltransferases | 0 | DIRECT |
| Heme-dependent catalases | 0 | DIRECT |
| DPP6 N-terminal domain-like | 0 | DIRECT |
| DPP6 catalytic domain-like | 0 | DIRECT |
| 2Fe-2S ferredoxin domains from multidomain proteins | 0 | DIRECT |
| beta-sandwich domain of Sec23/24 | 0 | DIRECT |
| Small-conductance potassium channel | 0 | DIRECT |
| HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
| Proprotein convertase P-domain | 0 | DIRECT |
| First domain of FERM | 0 | DIRECT |
| Hect, E3 ligase catalytic domain | 0 | DIRECT |
| VHS domain | 0 | DIRECT |
| MFPT repeat | 0 | DIRECT |
| U-box | 0 | DIRECT |
| Second domain of FERM | 0 | DIRECT |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Class II glutamine amidotransferases | 0 | DIRECT |
| Ras-binding domain, RBD | 0 | DIRECT |
| MOSC N-terminal domain-like | 0 | DIRECT |
| Cation efflux protein cytoplasmic domain-like | 0 | DIRECT |
| Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain | 0 | DIRECT |
| Aminoacid dehydrogenase-like, C-terminal domain | 0 | DIRECT |
| Myotubularin-like phosphatases | 0 | DIRECT |
| DEATH domain, DD | 0 | DIRECT |
| Quinoprotein alcohol dehydrogenase-like | 0 | DIRECT |
| Tetraspanin | 0 | DIRECT |
| Doublecortin (DC) | 0 | DIRECT |
| beta-Lactamase/D-ala carboxypeptidase | 0 | DIRECT |
| Ribonucleotide reductase-like | 0 | DIRECT |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
| Group II chaperonin (CCT, TRIC), ATPase domain | 0 | DIRECT |
| RecA protein-like (ATPase-domain) | 0 | DIRECT |
| Ubiquitin carboxyl-terminal hydrolase UCH-L | 0 | DIRECT |
| Trunk domain of Sec23/24 | 0 | DIRECT |
| AMPK-beta glycogen binding domain-like | 0 | DIRECT |
| DNA gyrase/MutL, N-terminal domain | 0 | DIRECT |
| L-aminoacid/polyamine oxidase | 0 | DIRECT |
| Spectrin repeat | 0 | DIRECT |
| Acylamino-acid-releasing enzyme, C-terminal donain | 0 | DIRECT |
| Glycogenin | 0 | DIRECT |
| Transducin (alpha subunit), insertion domain | 0 | DIRECT |
| Hexokinase | 0 | DIRECT |
| Band 7/SPFH domain | 0 | DIRECT |
| UBA domain | 0 | DIRECT |
| Phosphatidylethanolamine binding protein | 0 | DIRECT |
| Single strand DNA-binding domain, SSB | 0 | DIRECT |
| GYF domain | 0 | DIRECT |
| Phosphoribosyltransferases (PRTases) | 0 | DIRECT |
| MIF4G domain-like | 0 | DIRECT |
| BAR domain | 0 | DIRECT |
| Arginine methyltransferase | 0 | DIRECT |
| NADPH-cytochrome p450 reductase FAD-binding domain-like | 0 | DIRECT |
| L30e/L7ae ribosomal proteins | 0 | DIRECT |
| Lactate & malate dehydrogenases, C-terminal domain | 0 | DIRECT |
| Retrovirus zinc finger-like domains | 0 | DIRECT |
| Poly(ADP-ribose) polymerase, C-terminal domain | 0 | DIRECT |
| acyl-CoA oxidase C-terminal domains | 0 | DIRECT |
| Cullin homology domain | 0 | DIRECT |
| ALDH-like | 0 | DIRECT |
| acyl-CoA oxidase N-terminal domains | 0 | DIRECT |
| Troponin I | 0 | DIRECT |
| PEP carboxykinase N-terminal domain | 0 | DIRECT |
| Matrix metalloproteases, catalytic domain | 0 | DIRECT |
| Calpain large subunit, middle domain (domain III) | 0 | DIRECT |
| Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | DIRECT |
| D-aminoacid oxidase, N-terminal domain | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
| NHL repeat | 0 | DIRECT |
| Class I alpha-1;2-mannosidase, catalytic domain | 0 | DIRECT |
| Pyk2-associated protein beta ARF-GAP domain | 0 | DIRECT |
| Hormone receptor domain | 0 | DIRECT |
| Group II chaperonin (CCT, TRIC), intermediate domain | 0 | DIRECT |
| YWTD domain | 0 | DIRECT |
| WGR domain | 0 | DIRECT |
| Paired domain | 0 | DIRECT |
| Ovomucoid domain III-like | 0 | DIRECT |
| Fatty acid binding protein-like | 0 | DIRECT |
| Fibrinogen C-terminal domain-like | 0 | DIRECT |
| BEACH domain | 0 | DIRECT |
| Clc chloride channel | 0 | DIRECT |
| Proteasome subunits | 0 | DIRECT |
| Histone deacetylase, HDAC | 0 | DIRECT |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
| Inositol polyphosphate kinase (IPK) | 0 | DIRECT |
| Amylase, catalytic domain | 0 | DIRECT |
| Ubiquitin activating enzymes (UBA) | 0 | DIRECT |
| NADPH-cytochrome p450 reductase-like | 0 | DIRECT |
| NTF2-like | 0 | DIRECT |
| Hydantoinase (dihydropyrimidinase) | 0 | DIRECT |
| Cofilin-like | 0 | DIRECT |
| F1F0 ATP synthase subunit C | 0 | DIRECT |
| Alcohol dehydrogenase-like, C-terminal domain | 0 | DIRECT |
| Ran binding protein zinc finger-like | 0 | DIRECT |
| Ngr ectodomain-like | 0 | DIRECT |
| FHA domain | 0 | DIRECT |
| Integrin domains | 0 | DIRECT |
| Thyroglobulin type-1 domain | 0 | DIRECT |
| Rap/Ran-GAP | 0 | DIRECT |
| SMAD MH1 domain | 0 | DIRECT |
| Chitinase insertion domain | 0 | DIRECT |
| SWIRM domain | 0 | DIRECT |
| PB1 domain | 0 | DIRECT |
| Ribosomal protein L18 and S11 | 0 | DIRECT |
| Translational machinery components | 0 | DIRECT |
| Reprolysin-like | 0 | DIRECT |
| Bactericidal permeability-increasing protein, BPI | 0 | DIRECT |
| Calpain large subunit, catalytic domain (domain II) | 0 | DIRECT |
| CoA-binding domain | 0 | DIRECT |
| Clathrin coat assembly domain | 0 | DIRECT |
| Hypothetical protein c14orf129, hspc210 | 0 | DIRECT |
| Double-stranded RNA-binding domain (dsRBD) | 0 | DIRECT |
| Proton glutamate symport protein | 0 | DIRECT |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | DIRECT |
| Succinyl-CoA synthetase domains | 0 | DIRECT |
| HCDH C-domain-like | 0 | DIRECT |
| Phoshoinositide 3-kinase (PI3K) helical domain | 0 | DIRECT |
| Cdc48 domain 2-like | 0 | DIRECT |
| 28-residue LRR | 0 | DIRECT |
| Cytoplasmic domain of inward rectifier potassium channel | 0 | DIRECT |
| Pancreatic carboxypeptidases | 0 | DIRECT |
| Alcohol dehydrogenase-like, N-terminal domain | 0 | DIRECT |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Citrate synthase | 0 | DIRECT |
| Linker histone H1/H5 | 0 | DIRECT |
| Transducin (heterotrimeric G protein), gamma chain | 0 | DIRECT |
| Anticodon-binding domain of Class II aaRS | 0 | DIRECT |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
| FF domain | 0 | DIRECT |
| LEM domain | 0 | DIRECT |
| Smc hinge domain | 0 | DIRECT |
| Glycolipid transfer protein, GLTP | 0 | DIRECT |
| LacY-like proton/sugar symporter | 0 | DIRECT |
| Pepsin inhibitor-3 | 0 | DIRECT |
| PDI-like | 0 | DIRECT |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | DIRECT |
| Zn-finger domain of Sec23/24 | 0 | DIRECT |
| DEP domain | 0 | DIRECT |
| beta 1,4 galactosyltransferase (b4GalT1) | 0 | DIRECT |
| Formate/glycerate dehydrogenases, NAD-domain | 0 | DIRECT |
| SCF ubiquitin ligase complex WHB domain | 0 | DIRECT |
| UDP-glucose pyrophosphorylase | 0 | DIRECT |
| Phoshoinositide 3-kinase (PI3K), catalytic domain | 0 | DIRECT |
| Myb/SANT domain | 0 | DIRECT |
| YicI catalytic domain-like | 0 | DIRECT |
| Profilin (actin-binding protein) | 0 | DIRECT |
| SMAD domain | 0 | DIRECT |
| PDZ domain | 0 | DIRECT |
| HD domain | 0 | DIRECT |
| Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain | 0 | DIRECT |
| Lesion bypass DNA polymerase (Y-family), catalytic domain | 0 | DIRECT |
| Branched-chain alpha-keto acid dehydrogenase PP module | 0 | DIRECT |
| Subtilases | 0 | DIRECT |
| cAMP-binding domain | 0 | DIRECT |
| La domain | 0 | DIRECT |
| Branched-chain alpha-keto acid dehydrogenase Pyr module | 0 | DIRECT |
| Bacterial exopeptidase dimerisation domain | 0 | DIRECT |
| Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain | 0 | DIRECT |
| Intermediate filament protein, coiled coil region | 0 | DIRECT |
| DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
| Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | DIRECT |
| D-aminoacid oxidase-like | 0 | DIRECT |
| ATP-dependent protease Lon (La), catalytic domain | 0 | DIRECT |
| ValRS/IleRS/LeuRS editing domain | 0 | DIRECT |
| SAND domain | 0 | DIRECT |
| Aquaporin-like | 0 | DIRECT |
| Sec7 domain | 0 | DIRECT |
| HEAT repeat | 0 | DIRECT |
| Polo-box duplicated region | 0 | DIRECT |
| DNA gyrase/MutL, second domain | 0 | DIRECT |
| Cu,Zn superoxide dismutase-like | 0 | DIRECT |
| Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta | 0 | DIRECT |
| ARID domain | 0 | DIRECT |
| Pepsin-like | 0 | DIRECT |
| DNA repair protein MutS, domain III | 0 | DIRECT |
| Inositol polyphosphate 5-phosphatase (IPP5) | 0 | DIRECT |
| COMT-like | 0 | DIRECT |
| Calcium ATPase, transmembrane domain M | 0 | DIRECT |
| PDEase | 0 | DIRECT |
| Laminin G-like module | 0 | DIRECT |
| Cell cycle control phosphatase, catalytic domain | 0 | DIRECT |
| PEP carboxykinase C-terminal domain | 0 | DIRECT |
| Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | DIRECT |
| Choline kinase | 0 | DIRECT |
| MIR domain | 0 | DIRECT |
| POU-specific domain | 0 | DIRECT |
| Type II chitinase | 0 | DIRECT |
| Arylsulfatase | 0 | DIRECT |
| Glycerophosphoryl diester phosphodiesterase | 0 | DIRECT |
| Anticodon-binding domain | 0 | DIRECT |
| RhoGDI-like | 0 | DIRECT |
| Adenosine/AMP deaminase | 0 | DIRECT |
| FtsH protease domain-like | 0 | DIRECT |
| Domain of poly(ADP-ribose) polymerase | 0 | DIRECT |
| CRAL/TRIO N-terminal domain | 0 | DIRECT |
| Epoxide hydrolase | 0 | DIRECT |
| LDH N-terminal domain-like | 0 | DIRECT |
| Ribosomal protein S10 | 0 | DIRECT |
| Nop domain | 0 | DIRECT |
| Glutaminase | 0 | DIRECT |
| Hedgehog C-terminal (Hog) autoprocessing domain | 0 | DIRECT |
| Elafin-like | 0 | DIRECT |
| Skp1 dimerisation domain-like | 0 | DIRECT |
| Tim10/DDP | 0 | DIRECT |
| Chromo domain | 0 | DIRECT |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
| Cullin repeat | 0 | DIRECT |
| Tudor domain | 0 | DIRECT |
| Acyl-carrier protein (ACP) | 0 | DIRECT |
| Peptidylglycine alpha-hydroxylating monooxygenase, PHM | 0 | DIRECT |
| Carboxypeptidase regulatory domain | 0 | DIRECT |
| Serum paraoxonase/arylesterase 1, PON1 | 0 | DIRECT |
| Mitochondrial carrier | 0 | DIRECT |
| Hydantoinase (dihydropyrimidinase), catalytic domain | 0 | DIRECT |
| Glycosyl transferases group 1 | 0 | DIRECT |
| Type II DNA topoisomerase | 0 | DIRECT |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
| Phosphate binding protein-like | 0 | DIRECT |
| Group II chaperonin (CCT, TRIC), apical domain | 0 | DIRECT |
| Methionine aminopeptidase, insert domain | 0 | DIRECT |
| PLC-like (P variant) | 0 | DIRECT |
| Lamin A/C globular tail domain | 0 | DIRECT |
| Internalin LRR domain | 0 | DIRECT |
| FAD-dependent thiol oxidase | 0 | DIRECT |
| Blood coagulation inhibitor (disintegrin) | 0 | DIRECT |
| XPF/Rad1/Mus81 nuclease | 0 | DIRECT |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
| CUT domain | 0 | DIRECT |
| Helical domain of Sec23/24 | 0 | DIRECT |
| Sterol carrier protein, SCP | 0 | DIRECT |
| ets domain | 0 | DIRECT |
| Nucleosome core histones | 0.0002857 | DIRECT |
| WD40-repeat | 0.0003001 | DIRECT |
| Tandem AAA-ATPase domain | 0.0004563 | DIRECT |
| Protein kinases, catalytic subunit | 0.002346 | INHERITED FROM: positive chemotaxis variant || metabolic pathway variant || lipid synthesis increased || protein phosphorylation reduced || chemotaxis variant || organism environmental stimulus response variant || protein subcellular localization variant || drug induced gene expression variant || level of transgene expression variant || protein phosphorylation variant || protein expression variant || life span variant || chemical response variant || transgene expression reduced |
| MSP-like | 0.003093 | INHERITED FROM: fat content variant || developmental growth variant || lipid metabolism variant || larval arrest || growth variant || larval growth variant || slow growth |
| Tetratricopeptide repeat (TPR) | 0.01855 | INHERITED FROM: organism metabolism processing variant |
| Pleckstrin-homology domain (PH domain) | 0.02331 | INHERITED FROM: antimicrobial gene expression variant || organism metabolism processing variant || growth rate variant || dauer constitutive || organism environmental stimulus response variant || protein subcellular localization variant || drug induced gene expression variant || egg laying serotonin variant || egg laying imipramine resistant |
| Canonical RBD | 0.03246 | INHERITED FROM: RNA processing variant || mRNA export variant || RNA expression variant || sick || late larval arrest |
| L-arabinose binding protein-like | 0.04112 | INHERITED FROM: bromide chemotaxis defective || anion positive chemotaxis variant || iodide chemotaxis variant || positive chemotaxis defective || anion positive chemotaxis defective || cation positive chemotaxis defective || chemotaxis variant || organism environmental stimulus response variant || cation positive chemotaxis variant || bromide chemotaxis variant || iodide chemotaxis defective || magnesium chemotaxis defective || lithium chemotaxis defective || chemosensory response variant |
| G proteins | 0.04132 | INHERITED FROM: carbon dioxide response variant || organism metabolism processing variant || carbon dioxide avoidance variant || organism environmental stimulus response variant || drug induced gene expression variant || transgene subcellular localization variant || acetylcholinesterase inhibitor response variant |
| ABC transporter ATPase domain-like | 0.06421 | INHERITED FROM: RNAi response variant || cadmium hypersensitive || metal response variant || cadmium response variant |
| SH2 domain | 0.06573 | INHERITED FROM: aldicarb resistant || acetylcholinesterase inhibitor resistant |
| Actin/HSP70 | 0.09023 | INHERITED FROM: pathogen susceptibility increased || gene expression variant || protein interaction variant || transgene expression variant || protein aggregation variant || protein protein interaction variant || organism metabolism processing variant || cadmium hypersensitive || cadmium response variant || transgene expression increased |
| HLH, helix-loop-helix DNA-binding domain | 0.09753 | INHERITED FROM: aqueous positive chemotaxis defective || lysine chemotaxis defective || gene expression level reduced || ectopic expression transgene |
| Motor proteins | 0.09753 | INHERITED FROM: transgene subcellular localization variant |
| PAZ domain | 0.1009 | INHERITED FROM: gene expression variant || RNAi response variant || maintenance of gene silencing variant || mRNA levels increased || organism metabolism processing variant || siRNA expression variant || RNA expression variant || 21U RNA expression variant |
| Cold shock DNA-binding domain-like | 0.1009 | INHERITED FROM: sick |
| Protein serine/threonine phosphatase | 0.1069 | INHERITED FROM: antibody staining variant |
| Homeodomain | 0.1072 | INHERITED FROM: carbon dioxide response variant || carbon dioxide avoidance variant || ectopic expression transgene || sexually dimorphic physiology variant || touch resistant |
| CCCH zinc finger | 0.1128 | INHERITED FROM: transgene expression undetectable || ectopic expression transgene |
| ABC transporter transmembrane region | 0.1522 | INHERITED FROM: RNAi response variant || cadmium hypersensitive || metal response variant || cadmium response variant |
| Calcium ATPase, transduction domain A | 0.1567 | INHERITED FROM: drug hypersensitive || nicotine hypersensitive |
| Regulator of G-protein signaling, RGS | 0.1567 | INHERITED FROM: mechanosensation variant |
| Ankyrin repeat | 0.18 | INHERITED FROM: organism stress response variant || organism heat response variant || odorant negative chemotaxis defective || chemotaxis variant || octanol chemotaxis defective || octanol chemotaxis variant || chemosensory response variant |
| Tubulin, C-terminal domain | 0.1952 | INHERITED FROM: gene expression variant || protein interaction variant || transgene expression variant || protein aggregation variant || mechanosensation variant || nicotine response variant || protein protein interaction variant || organism metabolism processing variant || transgene subcellular localization variant || miRNA expression variant || touch resistant |
| Class I aminoacyl-tRNA synthetases (RS), catalytic domain | 0.2052 | INHERITED FROM: paraquat resistant || transgene expression increased || paraquat response variant || organism oxidative stress response variant || pesticide response variant |
| Dual specificity phosphatase-like | 0.2173 | INHERITED FROM: transgene expression variant || organism metabolism processing variant || level of transgene expression variant || transgene expression reduced |
| Metal cation-transporting ATPase, ATP-binding domain N | 0.2173 | INHERITED FROM: organism environmental stimulus response variant || drug hypersensitive || nicotine hypersensitive |
| Tubulin, GTPase domain | 0.2173 | INHERITED FROM: gene expression variant || protein interaction variant || transgene expression variant || protein aggregation variant || mechanosensation variant || nicotine response variant || protein protein interaction variant || organism metabolism processing variant || transgene subcellular localization variant || miRNA expression variant || touch resistant |
| FYVE, a phosphatidylinositol-3-phosphate binding domain | 0.2421 | INHERITED FROM: aldicarb resistant || acetylcholinesterase inhibitor resistant |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.2432 | INHERITED FROM: positive chemotaxis variant || aqueous chemosensory response variant || cholinergic agonist resistant || antihelmintic response variant || nicotine resistant || mechanosensation variant || enhanced taste aversion defective || hypoosmotic shock hypersensitive || organism environmental stimulus response variant || sodium chloride chemotaxis variant || chemical response variant || DMPP response variant |
| Adenylyl and guanylyl cyclase catalytic domain | 0.2618 | INHERITED FROM: positive chemotaxis variant || carbon dioxide response variant || bromide chemotaxis defective || anion positive chemotaxis variant || metabolic pathway variant || second messenger mediated signaling variant || iodide chemotaxis variant || AWC odorant chemotaxis variant || anion positive chemotaxis defective || cation positive chemotaxis defective || chemotaxis variant || organism environmental stimulus response variant || cation positive chemotaxis variant || bromide chemotaxis variant || iodide chemotaxis defective || magnesium chemotaxis defective || lithium chemotaxis defective || chemosensory response variant |
| Bromodomain | 0.2697 | INHERITED FROM: organism stress response variant || organism UV response variant || organism UV hypersensitive |
| Elongation factors | 0.2697 | INHERITED FROM: protein phosphorylation increased || mRNA levels increased || mRNA levels reduced || level of protein expression variant || protein aggregation variant || protein protein interaction variant || extended life span || protein expression reduced || mRNA expression variant || protein phosphorylation variant || protein modification variant || transgene expression increased || organism oxidative stress response variant |
| Growth factor receptor domain | 0.2697 | INHERITED FROM: chemotaxis variant || dauer arrest variant || mRNA expression variant || chemosensory response variant |
| Nicotinic receptor ligand binding domain-like | 0.2964 | INHERITED FROM: positive chemotaxis variant || aqueous chemosensory response variant || cholinergic agonist resistant || antihelmintic response variant || nicotine resistant || mechanosensation variant || enhanced taste aversion defective || hypoosmotic shock hypersensitive || organism environmental stimulus response variant || sodium chloride chemotaxis variant || chemical response variant || DMPP response variant |
| Sm motif of small nuclear ribonucleoproteins, SNRNP | 0.2998 | INHERITED FROM: protein aggregation variant || protein protein interaction variant || pattern of transgene expression variant || protein subcellular localization variant || sick || protein expression variant || transgene expression increased || pattern protein expression variant |
| Acetylcholinesterase-like | 0.2998 | INHERITED FROM: enzyme activity variant || acetylcholinesterase activity variant || enzyme activity reduced || acetylcholinesterase reduced |
| Meta-cation ATPase, catalytic domain P | 0.2998 | INHERITED FROM: organism environmental stimulus response variant || nicotine hypersensitive |
| Medium chain acyl-CoA dehydrogenase-like, C-terminal domain | 0.2998 | INHERITED FROM: transgene expression increased |
| Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains | 0.3336 | INHERITED FROM: transgene expression increased |
| Glutathione S-transferase (GST), N-terminal domain | 0.3596 | INHERITED FROM: organism electrophilic stress hypersensitive || organism heat hypersensitive || enzyme activity variant || organism stress response variant || cadmium hypersensitive || organism environmental stimulus response variant || cadmium response variant || paraquat response variant || enzyme activity reduced |
| Pumilio repeat | 0.3697 | INHERITED FROM: protein expression ectopic || protein subcellular localization variant || level of transgene expression variant || transgene expression increased |
| PHD domain | 0.4048 | INHERITED FROM: RNAi response variant || organism stress response variant || organism UV response variant || organism environmental stimulus response variant || protein methylation variant || RNAi resistant || organism UV hypersensitive || ectopic expression transgene |
| Papain-like | 0.4048 | INHERITED FROM: gene expression variant || protein interaction variant || transgene expression variant || protein aggregation variant || protein protein interaction variant || organism metabolism processing variant || hypoosmotic shock hypersensitive || pattern of transgene expression variant || osmotic integrity variant |
| Protein kinase cysteine-rich domain (cys2, phorbol-binding domain) | 0.4048 | INHERITED FROM: positive chemotaxis variant || antimicrobial gene expression variant || odorant chemosensory response variant || organism metabolism processing variant || odorant positive chemotaxis variant || protein subcellular localization variant || drug induced gene expression variant || organism pathogen response variant || drug resistant |
| BTB/POZ domain | 0.4252 | INHERITED FROM: L1 arrest || resistant to protein aggregation induced paralysis || protein aggregation induced paralysis || early larval arrest |
| I set domains | 0.4339 | INHERITED FROM: aldicarb resistant || growth rate variant || drug response variant |
| Pyridoxal-dependent decarboxylase | 0.4533 | INHERITED FROM: carbon dioxide response variant || carbon dioxide avoidance variant || drug response variant || egg laying response to drug variant |
| Erythroid transcription factor GATA-1 | 0.4533 | INHERITED FROM: gene expression variant || transgene expression variant || extended life span || organism pathogen response variant || life span variant || paraquat response variant || pesticide response variant |
| Myosin rod fragments | 0.4533 | INHERITED FROM: drug resistant |
| Cation efflux protein transmembrane domain-like | 0.4533 | INHERITED FROM: cadmium hypersensitive || metal response variant |
| HSP20 | 0.4533 | INHERITED FROM: pathogen susceptibility increased || gene expression variant || protein interaction variant || transgene expression variant || protein aggregation variant || protein protein interaction variant || organism metabolism processing variant || pattern of transgene expression variant || transgene subcellular localization variant || organism pathogen response variant |
| Multidrug efflux transporter AcrB transmembrane domain | 0.4626 | INHERITED FROM: odorant chemosensory response variant || negative chemotaxis variant || embryo osmotic integrity defective early emb |
| FKBP immunophilin/proline isomerase | 0.4904 | INHERITED FROM: gene expression variant || protein interaction variant || transgene expression variant || protein aggregation variant || protein protein interaction variant || organism metabolism processing variant || pattern of transgene expression variant || transgene subcellular localization variant |
| Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain | 0.4995 | INHERITED FROM: gene expression variant || transgene expression variant || organism metabolism processing variant || transgene expression increased |
| Histone lysine methyltransferases | 0.4995 | INHERITED FROM: somatic transgene silencing variant || RNAi response variant || maintenance of gene silencing variant || antibody staining variant || mRNA levels reduced || protein methylation variant || mRNA expression variant || protein modification variant || ectopic expression antibody || ectopic expression transgene |
| Gastric lipase | 0.5028 | INHERITED FROM: lipid metabolism variant |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0.5028 | INHERITED FROM: pathogen susceptibility increased || gene expression variant || protein interaction variant || transgene expression variant || protein aggregation variant || protein protein interaction variant || organism metabolism processing variant || cadmium hypersensitive || metal response variant || pattern of transgene expression variant || transgene subcellular localization variant || cadmium response variant || transgene expression increased |
| HMG-box | 0.5314 | INHERITED FROM: maintenance of gene silencing variant |
| Tetramerization domain of potassium channels | 0.5314 | INHERITED FROM: mechanosensation variant |
| UBC-related | 0.5438 | INHERITED FROM: gene expression variant || protein interaction variant || transgene expression variant || protein aggregation variant || protein protein interaction variant || organism metabolism processing variant || pattern of transgene expression variant || transgene subcellular localization variant |
| Voltage-gated potassium channels | 0.5617 | INHERITED FROM: egg laying phentolamine resistant || growth rate variant || adrenergic receptor antagonist response variant || egg laying levamisole resistant |
| Ubiquitin-related | 0.5739 | INHERITED FROM: protein interaction variant || transgene expression variant || protein aggregation variant || protein protein interaction variant || organism metabolism processing variant || hypersensitive to protein aggregation induced paralysis |
| Synaptotagmin-like (S variant) | 0.6069 | INHERITED FROM: aldicarb resistant || acetylcholinesterase inhibitor resistant || protein subcellular localization variant || acetylcholinesterase inhibitor response variant || protein expression variant || drug resistant || pattern protein expression variant |
| Osmotin, thaumatin-like protein | 0.6128 | INHERITED FROM: cadmium hypersensitive || metal response variant || level of transgene expression variant || cadmium response variant || transgene expression reduced |
| Adenain-like | 0.6128 | INHERITED FROM: sick |
| DNA replication initiator (cdc21/cdc54) N-terminal domain | 0.6128 | INHERITED FROM: hydroxyurea hypersensitive || drug hypersensitive || hydroxyurea response variant |
| Cytochrome P450 | 0.6134 | INHERITED FROM: cadmium hypersensitive || metal response variant || cadmium response variant |
| Chaperone J-domain | 0.6289 | INHERITED FROM: gene expression variant || protein interaction variant || transgene expression variant || protein aggregation variant || protein protein interaction variant || organism metabolism processing variant || pattern of transgene expression variant |
| Ubiquitin carboxyl-terminal hydrolase, UCH | 0.6356 | INHERITED FROM: gene expression variant || protein interaction variant || transgene expression variant || maintenance of gene silencing variant || protein aggregation variant || protein protein interaction variant || organism metabolism processing variant || pattern of transgene expression variant |
| Extended AAA-ATPase domain | 0.6486 | INHERITED FROM: shortened life span || sick |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0.677 | INHERITED FROM: life span variant |
| EF-hand modules in multidomain proteins | 0.677 | INHERITED FROM: chemical response variant |
| Transforming growth factor (TGF)-beta | 0.677 | INHERITED FROM: levamisole response variant || nicotine response variant || drug response variant || level of transgene expression variant || chemical response variant || transgene expression reduced |
| Lipovitellin-phosvitin complex, superhelical domain | 0.677 | INHERITED FROM: life span variant |
| Frizzled cysteine-rich domain | 0.677 | INHERITED FROM: protein expression variant |
| Crotonase-like | 0.6868 | INHERITED FROM: level of transgene expression variant |
| H-NOX domain | 0.7449 | INHERITED FROM: carbon dioxide response variant || carbon dioxide avoidance variant |
| 5' to 3' exonuclease catalytic domain | 0.7449 | INHERITED FROM: organism stress response variant |
| MIT domain | 0.7449 | INHERITED FROM: protein interaction variant || protein aggregation variant || protein protein interaction variant || transgene subcellular localization variant |
| 5' to 3' exonuclease, C-terminal subdomain | 0.7449 | INHERITED FROM: organism stress response variant |
| Cdc48 N-terminal domain-like | 0.7449 | INHERITED FROM: protein interaction variant || protein aggregation variant || protein protein interaction variant || transgene subcellular localization variant |
| Fibronectin type III | 0.7669 | INHERITED FROM: organism temperature response variant |
| Glutathione S-transferase (GST), C-terminal domain | 0.7953 | INHERITED FROM: organism electrophilic stress hypersensitive || enzyme activity variant || organism stress response variant || cadmium hypersensitive || organism environmental stimulus response variant || cadmium response variant || enzyme activity reduced |
| Tyrosine-dependent oxidoreductases | 0.8676 | INHERITED FROM: pheromone induced dauer formation variant |
| Calmodulin-like | 0.8907 | INHERITED FROM: protein interaction variant || protein aggregation variant || protein protein interaction variant || transgene subcellular localization variant |
| Insulin-like | 0.8918 | INHERITED FROM: fat content variant || lipid metabolism variant || dauer arrest variant || organism environmental stimulus response variant |
| DnaQ-like 3'-5' exonuclease | 0.9093 | INHERITED FROM: RNAi response variant |
| FAD/NAD-linked reductases, N-terminal and central domains | 0.9093 | INHERITED FROM: organism oxidative stress response variant |
| Extended PAW domain | 0.9093 | INHERITED FROM: protein interaction variant || protein aggregation variant || protein protein interaction variant || transgene subcellular localization variant |
| Ribonuclease PH domain 2-like | 0.9302 | INHERITED FROM: early larval arrest |
| Ribonuclease PH domain 1-like | 0.9302 | INHERITED FROM: early larval arrest |
| Nuclear receptor ligand-binding domain | 0.9427 | INHERITED FROM: SDS sensitive dauer || lipid metabolism variant || chemical hypersensitive || dauer resistance to harsh conditions variant || fat content increased |
| Laminin-type module | 0.9653 | INHERITED FROM: protein expression variant |
| Cyclophilin (peptidylprolyl isomerase) | 0.9855 | INHERITED FROM: gene expression variant || protein interaction variant || transgene expression variant || protein aggregation variant || protein protein interaction variant || organism metabolism processing variant || pattern of transgene expression variant || transgene subcellular localization variant |
| Rhodopsin-like | 1 | INHERITED FROM: aqueous adaptation defective || serotonin hypersensitive || drug withdrawal response variant || serotonin induced pumping variant || locomotion rate serotonin variant || serotonin response variant || serotonin resistant || organism pathogen response variant || biogenic amine receptor antagonist resistant || male tail curling serotonin variant || egg laying response to drug variant || serotonin induced fat reduction variant |
| RING finger domain, C3HC4 | 1 | INHERITED FROM: protein interaction variant || protein aggregation variant || protein protein interaction variant || organism metabolism processing variant || pattern of transgene expression variant || transgene subcellular localization variant |
| N-acetyl transferase, NAT | 1 | INHERITED FROM: ectopic expression transgene |
| Thiolase-related | 1 | INHERITED FROM: fat content variant || lipid metabolism variant |
| Leucine zipper domain | 1 | INHERITED FROM: mRNA levels reduced |
| Nuclear receptor | 1 | INHERITED FROM: SDS sensitive dauer || lipid metabolism variant || chemical hypersensitive || dauer resistance to harsh conditions variant || fat content increased |
| B-box zinc-binding domain | 1 | INHERITED FROM: protein interaction variant || protein aggregation variant || protein protein interaction variant || pattern of transgene expression variant || transgene subcellular localization variant |
| F-box domain | 1 | INHERITED FROM: resistant to protein aggregation induced paralysis || protein aggregation induced paralysis |
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| Mammalian PLC | 0 | Direct |
| Annexin | 0 | Direct |
| Oxysterol-binding protein | 0 | Direct |
| Ribokinase-like | 0 | Direct |
| Third domain of FERM | 0 | Direct |
| Armadillo repeat | 0 | Direct |
| Biotin dependent carboxylase carboxyltransferase domain | 0 | Direct |
| S-adenosylmethionine synthetase | 0 | Direct |
| PABC (PABP) domain | 0 | Direct |
| RNA editing terminal uridyl transferase 2, RET2, domain 2 | 0 | Direct |
| Cadherin | 0 | Direct |
| Clathrin adaptor core protein | 0 | Direct |
| Pancreatic carboxypeptidase, activation domain | 0 | Direct |
| GAPDH-like | 0 | Direct |
| Acyl-CoA thioesterase | 0 | Direct |
| Glycerol kinase | 0 | Direct |
| Regulator of chromosome condensation RCC1 | 0 | Direct |
| Inositol monophosphatase/fructose-1,6-bisphosphatase-like | 0 | Direct |
| Surp module (SWAP domain) | 0 | Direct |
| Translation initiation factor eIF4e | 0 | Direct |
| YbiA-like | 0 | Direct |
| Gamma-glutamyltranspeptidase-like | 0 | Direct |
| Myeloperoxidase-like | 0 | Direct |
| EGF-type module | 0 | Direct |
| Sec1/munc18-like (SM) proteins | 0 | Direct |
| Phosphoglucomutase, first 3 domains | 0 | Direct |
| 1,3-glucuronyltransferase | 0 | Direct |
| Protein prenyltransferases | 0 | Direct |
| Heme-dependent catalases | 0 | Direct |
| DPP6 N-terminal domain-like | 0 | Direct |
| DPP6 catalytic domain-like | 0 | Direct |
| 2Fe-2S ferredoxin domains from multidomain proteins | 0 | Direct |
| beta-sandwich domain of Sec23/24 | 0 | Direct |
| Small-conductance potassium channel | 0 | Direct |
| HSP40/DnaJ peptide-binding domain | 0 | Direct |
| Proprotein convertase P-domain | 0 | Direct |
| First domain of FERM | 0 | Direct |
| Hect, E3 ligase catalytic domain | 0 | Direct |
| VHS domain | 0 | Direct |
| MFPT repeat | 0 | Direct |
| U-box | 0 | Direct |
| Second domain of FERM | 0 | Direct |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Class II glutamine amidotransferases | 0 | Direct |
| Ras-binding domain, RBD | 0 | Direct |
| MOSC N-terminal domain-like | 0 | Direct |
| Cation efflux protein cytoplasmic domain-like | 0 | Direct |
| Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain | 0 | Direct |
| Aminoacid dehydrogenase-like, C-terminal domain | 0 | Direct |
| Myotubularin-like phosphatases | 0 | Direct |
| DEATH domain, DD | 0 | Direct |
| Quinoprotein alcohol dehydrogenase-like | 0 | Direct |
| Tetraspanin | 0 | Direct |
| Doublecortin (DC) | 0 | Direct |
| beta-Lactamase/D-ala carboxypeptidase | 0 | Direct |
| Ribonucleotide reductase-like | 0 | Direct |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
| Group II chaperonin (CCT, TRIC), ATPase domain | 0 | Direct |
| RecA protein-like (ATPase-domain) | 0 | Direct |
| Ubiquitin carboxyl-terminal hydrolase UCH-L | 0 | Direct |
| Trunk domain of Sec23/24 | 0 | Direct |
| AMPK-beta glycogen binding domain-like | 0 | Direct |
| DNA gyrase/MutL, N-terminal domain | 0 | Direct |
| L-aminoacid/polyamine oxidase | 0 | Direct |
| Spectrin repeat | 0 | Direct |
| Acylamino-acid-releasing enzyme, C-terminal donain | 0 | Direct |
| Glycogenin | 0 | Direct |
| Transducin (alpha subunit), insertion domain | 0 | Direct |
| Hexokinase | 0 | Direct |
| Band 7/SPFH domain | 0 | Direct |
| UBA domain | 0 | Direct |
| Phosphatidylethanolamine binding protein | 0 | Direct |
| Single strand DNA-binding domain, SSB | 0 | Direct |
| GYF domain | 0 | Direct |
| Phosphoribosyltransferases (PRTases) | 0 | Direct |
| MIF4G domain-like | 0 | Direct |
| BAR domain | 0 | Direct |
| Arginine methyltransferase | 0 | Direct |
| NADPH-cytochrome p450 reductase FAD-binding domain-like | 0 | Direct |
| L30e/L7ae ribosomal proteins | 0 | Direct |
| Lactate & malate dehydrogenases, C-terminal domain | 0 | Direct |
| Retrovirus zinc finger-like domains | 0 | Direct |
| Poly(ADP-ribose) polymerase, C-terminal domain | 0 | Direct |
| acyl-CoA oxidase C-terminal domains | 0 | Direct |
| Cullin homology domain | 0 | Direct |
| ALDH-like | 0 | Direct |
| acyl-CoA oxidase N-terminal domains | 0 | Direct |
| Troponin I | 0 | Direct |
| PEP carboxykinase N-terminal domain | 0 | Direct |
| Matrix metalloproteases, catalytic domain | 0 | Direct |
| Calpain large subunit, middle domain (domain III) | 0 | Direct |
| Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | Direct |
| D-aminoacid oxidase, N-terminal domain | 0 | Direct |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
| NHL repeat | 0 | Direct |
| Class I alpha-1;2-mannosidase, catalytic domain | 0 | Direct |
| Pyk2-associated protein beta ARF-GAP domain | 0 | Direct |
| Hormone receptor domain | 0 | Direct |
| Group II chaperonin (CCT, TRIC), intermediate domain | 0 | Direct |
| YWTD domain | 0 | Direct |
| WGR domain | 0 | Direct |
| Paired domain | 0 | Direct |
| Ovomucoid domain III-like | 0 | Direct |
| Fatty acid binding protein-like | 0 | Direct |
| Fibrinogen C-terminal domain-like | 0 | Direct |
| BEACH domain | 0 | Direct |
| Clc chloride channel | 0 | Direct |
| Proteasome subunits | 0 | Direct |
| Histone deacetylase, HDAC | 0 | Direct |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
| Inositol polyphosphate kinase (IPK) | 0 | Direct |
| Amylase, catalytic domain | 0 | Direct |
| Ubiquitin activating enzymes (UBA) | 0 | Direct |
| NADPH-cytochrome p450 reductase-like | 0 | Direct |
| NTF2-like | 0 | Direct |
| Hydantoinase (dihydropyrimidinase) | 0 | Direct |
| Cofilin-like | 0 | Direct |
| F1F0 ATP synthase subunit C | 0 | Direct |
| Alcohol dehydrogenase-like, C-terminal domain | 0 | Direct |
| Ran binding protein zinc finger-like | 0 | Direct |
| Ngr ectodomain-like | 0 | Direct |
| FHA domain | 0 | Direct |
| Integrin domains | 0 | Direct |
| Thyroglobulin type-1 domain | 0 | Direct |
| Rap/Ran-GAP | 0 | Direct |
| SMAD MH1 domain | 0 | Direct |
| Chitinase insertion domain | 0 | Direct |
| SWIRM domain | 0 | Direct |
| PB1 domain | 0 | Direct |
| Ribosomal protein L18 and S11 | 0 | Direct |
| Translational machinery components | 0 | Direct |
| Reprolysin-like | 0 | Direct |
| Bactericidal permeability-increasing protein, BPI | 0 | Direct |
| Calpain large subunit, catalytic domain (domain II) | 0 | Direct |
| CoA-binding domain | 0 | Direct |
| Clathrin coat assembly domain | 0 | Direct |
| Hypothetical protein c14orf129, hspc210 | 0 | Direct |
| Double-stranded RNA-binding domain (dsRBD) | 0 | Direct |
| Proton glutamate symport protein | 0 | Direct |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | Direct |
| Succinyl-CoA synthetase domains | 0 | Direct |
| HCDH C-domain-like | 0 | Direct |
| Phoshoinositide 3-kinase (PI3K) helical domain | 0 | Direct |
| Cdc48 domain 2-like | 0 | Direct |
| 28-residue LRR | 0 | Direct |
| Cytoplasmic domain of inward rectifier potassium channel | 0 | Direct |
| Pancreatic carboxypeptidases | 0 | Direct |
| Alcohol dehydrogenase-like, N-terminal domain | 0 | Direct |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Citrate synthase | 0 | Direct |
| Linker histone H1/H5 | 0 | Direct |
| Transducin (heterotrimeric G protein), gamma chain | 0 | Direct |
| Anticodon-binding domain of Class II aaRS | 0 | Direct |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
| FF domain | 0 | Direct |
| LEM domain | 0 | Direct |
| Smc hinge domain | 0 | Direct |
| Glycolipid transfer protein, GLTP | 0 | Direct |
| LacY-like proton/sugar symporter | 0 | Direct |
| Pepsin inhibitor-3 | 0 | Direct |
| PDI-like | 0 | Direct |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | Direct |
| Zn-finger domain of Sec23/24 | 0 | Direct |
| DEP domain | 0 | Direct |
| beta 1,4 galactosyltransferase (b4GalT1) | 0 | Direct |
| Formate/glycerate dehydrogenases, NAD-domain | 0 | Direct |
| SCF ubiquitin ligase complex WHB domain | 0 | Direct |
| UDP-glucose pyrophosphorylase | 0 | Direct |
| Phoshoinositide 3-kinase (PI3K), catalytic domain | 0 | Direct |
| Myb/SANT domain | 0 | Direct |
| YicI catalytic domain-like | 0 | Direct |
| Profilin (actin-binding protein) | 0 | Direct |
| SMAD domain | 0 | Direct |
| PDZ domain | 0 | Direct |
| HD domain | 0 | Direct |
| Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain | 0 | Direct |
| Lesion bypass DNA polymerase (Y-family), catalytic domain | 0 | Direct |
| Branched-chain alpha-keto acid dehydrogenase PP module | 0 | Direct |
| Subtilases | 0 | Direct |
| cAMP-binding domain | 0 | Direct |
| La domain | 0 | Direct |
| Branched-chain alpha-keto acid dehydrogenase Pyr module | 0 | Direct |
| Bacterial exopeptidase dimerisation domain | 0 | Direct |
| Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain | 0 | Direct |
| Intermediate filament protein, coiled coil region | 0 | Direct |
| DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
| Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | Direct |
| D-aminoacid oxidase-like | 0 | Direct |
| ATP-dependent protease Lon (La), catalytic domain | 0 | Direct |
| ValRS/IleRS/LeuRS editing domain | 0 | Direct |
| SAND domain | 0 | Direct |
| Aquaporin-like | 0 | Direct |
| Sec7 domain | 0 | Direct |
| HEAT repeat | 0 | Direct |
| Polo-box duplicated region | 0 | Direct |
| DNA gyrase/MutL, second domain | 0 | Direct |
| Cu,Zn superoxide dismutase-like | 0 | Direct |
| Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta | 0 | Direct |
| ARID domain | 0 | Direct |
| Pepsin-like | 0 | Direct |
| DNA repair protein MutS, domain III | 0 | Direct |
| Inositol polyphosphate 5-phosphatase (IPP5) | 0 | Direct |
| COMT-like | 0 | Direct |
| Calcium ATPase, transmembrane domain M | 0 | Direct |
| PDEase | 0 | Direct |
| Laminin G-like module | 0 | Direct |
| Cell cycle control phosphatase, catalytic domain | 0 | Direct |
| PEP carboxykinase C-terminal domain | 0 | Direct |
| Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | Direct |
| Choline kinase | 0 | Direct |
| MIR domain | 0 | Direct |
| POU-specific domain | 0 | Direct |
| Type II chitinase | 0 | Direct |
| Arylsulfatase | 0 | Direct |
| Glycerophosphoryl diester phosphodiesterase | 0 | Direct |
| Anticodon-binding domain | 0 | Direct |
| RhoGDI-like | 0 | Direct |
| Adenosine/AMP deaminase | 0 | Direct |
| FtsH protease domain-like | 0 | Direct |
| Domain of poly(ADP-ribose) polymerase | 0 | Direct |
| CRAL/TRIO N-terminal domain | 0 | Direct |
| Epoxide hydrolase | 0 | Direct |
| LDH N-terminal domain-like | 0 | Direct |
| Ribosomal protein S10 | 0 | Direct |
| Nop domain | 0 | Direct |
| Glutaminase | 0 | Direct |
| Hedgehog C-terminal (Hog) autoprocessing domain | 0 | Direct |
| Elafin-like | 0 | Direct |
| Skp1 dimerisation domain-like | 0 | Direct |
| Tim10/DDP | 0 | Direct |
| Chromo domain | 0 | Direct |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
| Cullin repeat | 0 | Direct |
| Tudor domain | 0 | Direct |
| Acyl-carrier protein (ACP) | 0 | Direct |
| Peptidylglycine alpha-hydroxylating monooxygenase, PHM | 0 | Direct |
| Carboxypeptidase regulatory domain | 0 | Direct |
| Serum paraoxonase/arylesterase 1, PON1 | 0 | Direct |
| Mitochondrial carrier | 0 | Direct |
| Hydantoinase (dihydropyrimidinase), catalytic domain | 0 | Direct |
| Glycosyl transferases group 1 | 0 | Direct |
| Type II DNA topoisomerase | 0 | Direct |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
| Phosphate binding protein-like | 0 | Direct |
| Group II chaperonin (CCT, TRIC), apical domain | 0 | Direct |
| Methionine aminopeptidase, insert domain | 0 | Direct |
| PLC-like (P variant) | 0 | Direct |
| Lamin A/C globular tail domain | 0 | Direct |
| Internalin LRR domain | 0 | Direct |
| FAD-dependent thiol oxidase | 0 | Direct |
| Blood coagulation inhibitor (disintegrin) | 0 | Direct |
| XPF/Rad1/Mus81 nuclease | 0 | Direct |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
| CUT domain | 0 | Direct |
| Helical domain of Sec23/24 | 0 | Direct |
| Sterol carrier protein, SCP | 0 | Direct |
| ets domain | 0 | Direct |
| Nucleosome core histones | 0.0002857 | Direct |
| WD40-repeat | 0.0003001 | Direct |
| Tandem AAA-ATPase domain | 0.0004563 | Direct |
| Protein kinases, catalytic subunit | 0.002346 | Inherited |
| MSP-like | 0.003093 | Inherited |
| Tetratricopeptide repeat (TPR) | 0.01855 | Inherited |
| Pleckstrin-homology domain (PH domain) | 0.02331 | Inherited |
| Canonical RBD | 0.03246 | Inherited |
| L-arabinose binding protein-like | 0.04112 | Inherited |
| G proteins | 0.04132 | Inherited |
| ABC transporter ATPase domain-like | 0.06421 | Inherited |
| SH2 domain | 0.06573 | Inherited |
| Actin/HSP70 | 0.09023 | Inherited |
| HLH, helix-loop-helix DNA-binding domain | 0.09753 | Inherited |
| Motor proteins | 0.09753 | Inherited |
| PAZ domain | 0.1009 | Inherited |
| Cold shock DNA-binding domain-like | 0.1009 | Inherited |
| Protein serine/threonine phosphatase | 0.1069 | Inherited |
| Homeodomain | 0.1072 | Inherited |
| CCCH zinc finger | 0.1128 | Inherited |
| ABC transporter transmembrane region | 0.1522 | Inherited |
| Calcium ATPase, transduction domain A | 0.1567 | Inherited |
| Regulator of G-protein signaling, RGS | 0.1567 | Inherited |
| Ankyrin repeat | 0.18 | Inherited |
| Tubulin, C-terminal domain | 0.1952 | Inherited |
| Class I aminoacyl-tRNA synthetases (RS), catalytic domain | 0.2052 | Inherited |
| Dual specificity phosphatase-like | 0.2173 | Inherited |
| Metal cation-transporting ATPase, ATP-binding domain N | 0.2173 | Inherited |
| Tubulin, GTPase domain | 0.2173 | Inherited |
| FYVE, a phosphatidylinositol-3-phosphate binding domain | 0.2421 | Inherited |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.2432 | Inherited |
| Adenylyl and guanylyl cyclase catalytic domain | 0.2618 | Inherited |
| Bromodomain | 0.2697 | Inherited |
| Elongation factors | 0.2697 | Inherited |
| Growth factor receptor domain | 0.2697 | Inherited |
| Nicotinic receptor ligand binding domain-like | 0.2964 | Inherited |
| Sm motif of small nuclear ribonucleoproteins, SNRNP | 0.2998 | Inherited |
| Acetylcholinesterase-like | 0.2998 | Inherited |
| Meta-cation ATPase, catalytic domain P | 0.2998 | Inherited |
| Medium chain acyl-CoA dehydrogenase-like, C-terminal domain | 0.2998 | Inherited |
| Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains | 0.3336 | Inherited |
| Glutathione S-transferase (GST), N-terminal domain | 0.3596 | Inherited |
| Pumilio repeat | 0.3697 | Inherited |
| PHD domain | 0.4048 | Inherited |
| Papain-like | 0.4048 | Inherited |
| Protein kinase cysteine-rich domain (cys2, phorbol-binding domain) | 0.4048 | Inherited |
| BTB/POZ domain | 0.4252 | Inherited |
| I set domains | 0.4339 | Inherited |
| Pyridoxal-dependent decarboxylase | 0.4533 | Inherited |
| Erythroid transcription factor GATA-1 | 0.4533 | Inherited |
| Myosin rod fragments | 0.4533 | Inherited |
| Cation efflux protein transmembrane domain-like | 0.4533 | Inherited |
| HSP20 | 0.4533 | Inherited |
| Multidrug efflux transporter AcrB transmembrane domain | 0.4626 | Inherited |
| FKBP immunophilin/proline isomerase | 0.4904 | Inherited |
| Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain | 0.4995 | Inherited |
| Histone lysine methyltransferases | 0.4995 | Inherited |
| Gastric lipase | 0.5028 | Inherited |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0.5028 | Inherited |
| HMG-box | 0.5314 | Inherited |
| Tetramerization domain of potassium channels | 0.5314 | Inherited |
| UBC-related | 0.5438 | Inherited |
| Voltage-gated potassium channels | 0.5617 | Inherited |
| Ubiquitin-related | 0.5739 | Inherited |
| Synaptotagmin-like (S variant) | 0.6069 | Inherited |
| Osmotin, thaumatin-like protein | 0.6128 | Inherited |
| Adenain-like | 0.6128 | Inherited |
| DNA replication initiator (cdc21/cdc54) N-terminal domain | 0.6128 | Inherited |
| Cytochrome P450 | 0.6134 | Inherited |
| Chaperone J-domain | 0.6289 | Inherited |
| Ubiquitin carboxyl-terminal hydrolase, UCH | 0.6356 | Inherited |
| Extended AAA-ATPase domain | 0.6486 | Inherited |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0.677 | Inherited |
| EF-hand modules in multidomain proteins | 0.677 | Inherited |
| Transforming growth factor (TGF)-beta | 0.677 | Inherited |
| Lipovitellin-phosvitin complex, superhelical domain | 0.677 | Inherited |
| Frizzled cysteine-rich domain | 0.677 | Inherited |
| Crotonase-like | 0.6868 | Inherited |
| H-NOX domain | 0.7449 | Inherited |
| 5' to 3' exonuclease catalytic domain | 0.7449 | Inherited |
| MIT domain | 0.7449 | Inherited |
| 5' to 3' exonuclease, C-terminal subdomain | 0.7449 | Inherited |
| Cdc48 N-terminal domain-like | 0.7449 | Inherited |
| Fibronectin type III | 0.7669 | Inherited |
| Glutathione S-transferase (GST), C-terminal domain | 0.7953 | Inherited |
| Tyrosine-dependent oxidoreductases | 0.8676 | Inherited |
| Calmodulin-like | 0.8907 | Inherited |
| Insulin-like | 0.8918 | Inherited |
| DnaQ-like 3'-5' exonuclease | 0.9093 | Inherited |
| FAD/NAD-linked reductases, N-terminal and central domains | 0.9093 | Inherited |
| Extended PAW domain | 0.9093 | Inherited |
| Ribonuclease PH domain 2-like | 0.9302 | Inherited |
| Ribonuclease PH domain 1-like | 0.9302 | Inherited |
| Nuclear receptor ligand-binding domain | 0.9427 | Inherited |
| Laminin-type module | 0.9653 | Inherited |
| Cyclophilin (peptidylprolyl isomerase) | 0.9855 | Inherited |
| Rhodopsin-like | 1 | Inherited |
| RING finger domain, C3HC4 | 1 | Inherited |
| N-acetyl transferase, NAT | 1 | Inherited |
| Thiolase-related | 1 | Inherited |
| Leucine zipper domain | 1 | Inherited |
| Nuclear receptor | 1 | Inherited |
| B-box zinc-binding domain | 1 | Inherited |
| F-box domain | 1 | Inherited |
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A presence/absence matrix is generated using protein domain
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Supra-domain (including individual superfamily)
(show details)
Supra-domains annotated to this WP term (Not in SPWP)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
| WGR domain-like | 0 | DIRECT |
| MIR domain | 0 | DIRECT |
| R3H domain | 0 | DIRECT |
| Cdc48 domain 2-like | 0 | DIRECT |
| Nucleotidyltransferase | 0 | DIRECT |
| TGS-like | 0 | DIRECT |
| Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | DIRECT |
| GYF domain | 0 | DIRECT |
| Hypothetical protein c14orf129, hspc210 | 0 | DIRECT |
| Intermediate filament protein, coiled coil region | 0 | DIRECT |
| Fibrinogen C-terminal domain-like | 0 | DIRECT |
| GroEL apical domain-like | 0 | DIRECT |
| GAT-like domain | 0 | DIRECT |
| SMAD/FHA domain | 0 | DIRECT |
| SCP-like | 0 | DIRECT |
| SMAD MH1 domain | 0 | DIRECT |
| Retrovirus zinc finger-like domains | 0 | DIRECT |
| Hect, E3 ligase catalytic domain | 0 | DIRECT |
| Ribosomal protein L10-like | 0 | DIRECT |
| Second domain of FERM | 0 | DIRECT |
| Seven-hairpin glycosidases | 0 | DIRECT |
| Heme-dependent peroxidases | 0 | DIRECT |
| Cu,Zn superoxide dismutase-like | 0 | DIRECT |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
| 2Fe-2S ferredoxin-like | 0 | DIRECT |
| eIF4e-like | 0 | DIRECT |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
| SIS domain | 0 | DIRECT |
| Subtilisin-like | 0 | DIRECT |
| MOSC N-terminal domain-like | 0 | DIRECT |
| PGBD-like | 0 | DIRECT |
| PHM/PNGase F | 0 | DIRECT |
| ArfGap/RecO-like zinc finger | 0 | DIRECT |
| Bacterial exopeptidase dimerisation domain | 0 | DIRECT |
| Nucleoporin domain | 0 | DIRECT |
| Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | DIRECT |
| Chitinase insertion domain | 0 | DIRECT |
| ENTH/VHS domain | 0 | DIRECT |
| Class II aaRS ABD-related | 0 | DIRECT |
| Carbohydrate phosphatase | 0 | DIRECT |
| Integrin domains | 0 | DIRECT |
| Succinyl-CoA synthetase domains | 0 | DIRECT |
| Alpha-L RNA-binding motif | 0 | DIRECT |
| LEM domain | 0 | DIRECT |
| Periplasmic binding protein-like II | 0 | DIRECT |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | DIRECT |
| GHMP Kinase, C-terminal domain | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
| Aquaporin-like | 0 | DIRECT |
| PEBP-like | 0 | DIRECT |
| Pentein | 0 | DIRECT |
| DNA repair protein MutS, domain III | 0 | DIRECT |
| Elafin-like | 0 | DIRECT |
| MgtE membrane domain-like | 0 | DIRECT |
| Protease propeptides/inhibitors | 0 | DIRECT |
| L30e-like | 0 | DIRECT |
| CAD & PB1 domains | 0 | DIRECT |
| 3-carboxy-cis,cis-mucoante lactonizing enzyme | 0 | DIRECT |
| CRAL/TRIO N-terminal domain | 0 | DIRECT |
| Tricorn protease domain 2 | 0 | DIRECT |
| Polo-box domain | 0 | DIRECT |
| Citrate synthase | 0 | DIRECT |
| Calpain large subunit, middle domain (domain III) | 0 | DIRECT |
| Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | DIRECT |
| Phosphoglucomutase, first 3 domains | 0 | DIRECT |
| ARID-like | 0 | DIRECT |
| PYP-like sensor domain (PAS domain) | 0 | DIRECT |
| PABC (PABP) domain | 0 | DIRECT |
| Sec7 domain | 0 | DIRECT |
| PK beta-barrel domain-like | 0 | DIRECT |
| BEACH domain | 0 | DIRECT |
| Ribosomal protein S10 | 0 | DIRECT |
| Cullin homology domain | 0 | DIRECT |
| Smc hinge domain | 0 | DIRECT |
| TK C-terminal domain-like | 0 | DIRECT |
| PEP carboxykinase-like | 0 | DIRECT |
| Integrin alpha N-terminal domain | 0 | DIRECT |
| Activating enzymes of the ubiquitin-like proteins | 0 | DIRECT |
| Subdomain of clathrin and coatomer appendage domain | 0 | DIRECT |
| GroEL-intermediate domain like | 0 | DIRECT |
| Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0 | DIRECT |
| Tudor/PWWP/MBT | 0 | DIRECT |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
| Hormone receptor domain | 0 | DIRECT |
| FtsH protease domain-like | 0 | DIRECT |
| Helical domain of Sec23/24 | 0 | DIRECT |
| Alkaline phosphatase-like | 0 | DIRECT |
| FF domain | 0 | DIRECT |
| Translational machinery components | 0 | DIRECT |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | DIRECT |
| Ribokinase-like | 0 | DIRECT |
| Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
| Bactericidal permeability-increasing protein, BPI | 0 | DIRECT |
| Tubby C-terminal domain-like | 0 | DIRECT |
| ValRS/IleRS/LeuRS editing domain | 0 | DIRECT |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
| Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | DIRECT |
| YbiA-like | 0 | DIRECT |
| GroEL equatorial domain-like | 0 | DIRECT |
| F1F0 ATP synthase subunit C | 0 | DIRECT |
| Sec1/munc18-like (SM) proteins | 0 | DIRECT |
| Thyroglobulin type-1 domain | 0 | DIRECT |
| Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| DEATH domain | 0 | DIRECT |
| Annexin | 0 | DIRECT |
| Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | DIRECT |
| Surp module (SWAP domain) | 0 | DIRECT |
| Profilin (actin-binding protein) | 0 | DIRECT |
| Terpenoid cyclases/Protein prenyltransferases | 0 | DIRECT |
| Pepsin inhibitor-3 | 0 | DIRECT |
| Small-conductance potassium channel | 0 | DIRECT |
| Class I glutamine amidotransferase-like | 0 | DIRECT |
| Carbon-nitrogen hydrolase | 0 | DIRECT |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0 | DIRECT |
| Aminoacid dehydrogenase-like, N-terminal domain | 0 | DIRECT |
| Cullin repeat-like | 0 | DIRECT |
| Skp1 dimerisation domain-like | 0 | DIRECT |
| Cystatin/monellin | 0 | DIRECT |
| Domain of poly(ADP-ribose) polymerase | 0 | DIRECT |
| Nop domain | 0 | DIRECT |
| ThrRS/AlaRS common domain | 0 | DIRECT |
| Thiamin diphosphate-binding fold (THDP-binding) | 0 | DIRECT |
| lambda repressor-like DNA-binding domains | 0 | DIRECT |
| KA1-like | 0 | DIRECT |
| Ribosomal proteins S24e, L23 and L15e | 0 | DIRECT |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
| Spectrin repeat | 0 | DIRECT |
| Galactose oxidase, central domain | 0 | DIRECT |
| Acid phosphatase/Vanadium-dependent haloperoxidase | 0 | DIRECT |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
| Ran binding protein zinc finger-like | 0 | DIRECT |
| L-aspartase-like | 0 | DIRECT |
| Clc chloride channel | 0 | DIRECT |
| Heme-dependent catalase-like | 0 | DIRECT |
| Transducin (heterotrimeric G protein), gamma chain | 0 | DIRECT |
| Cation efflux protein cytoplasmic domain-like | 0 | DIRECT |
| beta-lactamase/transpeptidase-like | 0 | DIRECT |
| SAICAR synthase-like | 0 | DIRECT |
| Troponin coil-coiled subunits | 0 | DIRECT |
| LDH C-terminal domain-like | 0 | DIRECT |
| PAP/OAS1 substrate-binding domain | 0 | DIRECT |
| Zn-binding ribosomal proteins | 0 | DIRECT |
| ISP domain | 0 | DIRECT |
| Zn-finger domain of Sec23/24 | 0 | DIRECT |
| Blood coagulation inhibitor (disintegrin) | 0 | DIRECT |
| Rap/Ran-GAP | 0 | DIRECT |
| ADP-ribosylation | 0 | DIRECT |
| PEP carboxykinase N-terminal domain | 0 | DIRECT |
| Glycolipid transfer protein, GLTP | 0 | DIRECT |
| Hedgehog/intein (Hint) domain | 0 | DIRECT |
| FAD-dependent thiol oxidase | 0 | DIRECT |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | DIRECT |
| Clathrin adaptor appendage domain | 0 | DIRECT |
| DNA ligase/mRNA capping enzyme, catalytic domain | 0 | DIRECT |
| Type II DNA topoisomerase | 0 | DIRECT |
| Proton glutamate symport protein | 0 | DIRECT |
| MFPT repeat-like | 0 | DIRECT |
| Oxysterol-binding protein-like | 0 | DIRECT |
| Cadherin-like | 0 | DIRECT |
| PLC-like phosphodiesterases | 0 | DIRECT |
| Ferritin-like | 0 | DIRECT |
| Doublecortin (DC) | 0 | DIRECT |
| Restriction endonuclease-like | 0 | DIRECT |
| JAB1/MPN domain | 0 | DIRECT |
| ALDH-like | 0 | DIRECT |
| Formate/glycerate dehydrogenase catalytic domain-like | 0 | DIRECT |
| Sec63 N-terminal domain-like | 0 | DIRECT |
| Phosphoenolpyruvate/pyruvate domain | 0 | DIRECT |
| SAND domain-like | 0 | DIRECT |
| cAMP-binding domain-like | 0 | DIRECT |
| DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
| YWTD domain | 0 | DIRECT |
| Arginase/deacetylase | 0 | DIRECT |
| Carboxypeptidase regulatory domain-like | 0 | DIRECT |
| Tim10-like | 0 | DIRECT |
| Transducin (alpha subunit), insertion domain | 0 | DIRECT |
| SPOC domain-like | 0 | DIRECT |
| Riboflavin synthase domain-like | 0 | DIRECT |
| Flavoproteins | 0 | DIRECT |
| Mitochondrial carrier | 0 | DIRECT |
| dsRNA-binding domain-like | 0 | DIRECT |
| S-adenosylmethionine synthetase | 0 | DIRECT |
| Cytochrome c | 0 | DIRECT |
| Lamin A/C globular tail domain | 0 | DIRECT |
| P-loop containing nucleoside triphosphate hydrolases | 1.788e-05 | DIRECT |
| Protein kinase-like (PK-like) | 0.0003731 | DIRECT |
| WD40 repeat-like | 0.002118 | INHERITED FROM: protein aggregation variant || protein protein interaction variant || organism metabolism processing variant || protein aggregation induced paralysis || late larval arrest |
| PapD-like | 0.002254 | INHERITED FROM: fat content variant || developmental growth variant || lipid metabolism variant || larval arrest || growth variant || larval growth variant || slow growth |
| Histone-fold | 0.002254 | INHERITED FROM: stress induced lethality increased || pathogen susceptibility increased || organism osmotic stress response variant || organism hypertonic lethality increased || stress induced lethality variant |
| PH domain-like | 0.002288 | INHERITED FROM: organism metabolism processing variant || growth rate variant || copper response variant || organism environmental stimulus response variant || drug induced gene expression variant || transgene subcellular localization variant || protein phosphorylation variant || protein expression variant |
| PDZ domain-like | 0.007977 | INHERITED FROM: drug response variant |
| Periplasmic binding protein-like I | 0.009048 | INHERITED FROM: osmotic avoidance defective || bromide chemotaxis defective || fat content variant || metabolic pathway variant || second messenger mediated signaling variant || iodide chemotaxis variant || positive chemotaxis defective || lipid metabolism variant || AWC odorant chemotaxis variant || carbon dioxide avoidance variant || chemotaxis variant || organism environmental stimulus response variant || bromide chemotaxis variant || memory retention defective || iodide chemotaxis defective || magnesium chemotaxis defective || lithium chemotaxis defective || chemical response variant || chemosensory response variant |
| TPR-like | 0.01321 | INHERITED FROM: associative learning variant || light body touch resistant || positive chemotaxis defective || ammonium chloride chemotaxis variant || chemotaxis variant || dauer arrest variant || pattern of transgene expression variant |
| Actin-like ATPase domain | 0.01902 | INHERITED FROM: pathogen susceptibility increased || protein interaction variant || transgene expression variant || protein aggregation variant || protein protein interaction variant || organism metabolism processing variant || cadmium hypersensitive || cadmium response variant |
| "Winged helix" DNA-binding domain | 0.03984 | INHERITED FROM: gene expression variant || germline transgene silencing variant || protein aggregation variant || protein protein interaction variant || organism metabolism processing variant || shortened life span || organism hypertonic lethality increased || paraquat hypersensitive || life span variant || spontaneous mutation rate increased || protein expression increased |
| SH2 domain | 0.04492 | INHERITED FROM: aldicarb resistant || acetylcholinesterase inhibitor resistant |
| Homeodomain-like | 0.05608 | INHERITED FROM: carbon dioxide response variant || growth rate variant || imipramine resistant || carbon dioxide avoidance variant || inhibitor of serotonin uptake variant || adrenergic receptor antagonist response variant || egg laying imipramine resistant || ectopic expression transgene || sexually dimorphic physiology variant || touch resistant |
| ARM repeat | 0.06272 | INHERITED FROM: gene expression variant || RNAi response variant || organism metabolism processing variant || sick || protein expression variant |
| PAZ domain | 0.07326 | INHERITED FROM: somatic transgene silencing variant || gene expression variant || RNAi response variant || maintenance of gene silencing variant || mRNA levels increased || organism metabolism processing variant || siRNA expression variant || RNA expression variant || 21U RNA expression variant |
| HLH, helix-loop-helix DNA-binding domain | 0.07394 | INHERITED FROM: aqueous positive chemotaxis variant || positive chemotaxis defective || organism metabolism processing variant || aqueous positive chemotaxis defective || chemotaxis variant || lysine chemotaxis defective || gene expression level reduced || ectopic expression transgene |
| CCCH zinc finger | 0.09337 | INHERITED FROM: transgene expression undetectable || ectopic expression transgene |
| HSP20-like chaperones | 0.09337 | INHERITED FROM: pathogen susceptibility increased || protein interaction variant || transgene expression variant || protein aggregation variant || protein protein interaction variant || organism metabolism processing variant || cadmium hypersensitive || metal response variant || pattern of transgene expression variant || transgene subcellular localization variant || cadmium response variant || life span variant |
| Nucleic acid-binding proteins | 0.0966 | INHERITED FROM: hydroxyurea hypersensitive || hydroxyurea response variant || sick |
| Calcium ATPase, transmembrane domain M | 0.1053 | INHERITED FROM: lipid composition variant || drug hypersensitive || nicotine hypersensitive |
| Translation proteins | 0.1053 | INHERITED FROM: gene expression variant || protein phosphorylation increased || transgene expression variant || mRNA levels increased || mRNA levels reduced || protein aggregation variant || protein protein interaction variant || organism metabolism processing variant || extended life span || protein expression reduced || mRNA expression variant || protein phosphorylation variant || sick || protein modification variant || organism oxidative stress response variant |
| RNI-like | 0.1101 | INHERITED FROM: resistant to protein aggregation induced paralysis || protein aggregation induced paralysis |
| Ankyrin repeat | 0.1171 | INHERITED FROM: organism stress response variant || organism heat response variant || odorant negative chemotaxis defective || chemotaxis variant || octanol chemotaxis defective || octanol chemotaxis variant || chemosensory response variant |
| Metal cation-transporting ATPase, ATP-binding domain N | 0.1187 | INHERITED FROM: lipid composition variant || drug hypersensitive || nicotine hypersensitive |
| Chromo domain-like | 0.1187 | INHERITED FROM: germline transgene silencing variant || maintenance of gene silencing variant || organism UV response variant || organism UV hypersensitive || ectopic expression transgene |
| EGF/Laminin | 0.1295 | INHERITED FROM: odorant negative chemotaxis defective || octanol chemotaxis defective || protein expression reduced || negative chemotaxis variant || octanol chemotaxis variant |
| Calcium ATPase, transduction domain A | 0.1338 | INHERITED FROM: organism environmental stimulus response variant || drug hypersensitive || nicotine hypersensitive |
| Quinoprotein alcohol dehydrogenase-like | 0.1508 | INHERITED FROM: L2 arrest || mid larval arrest || early larval arrest || fat content increased |
| RNA-binding domain, RBD | 0.1623 | INHERITED FROM: RNA processing variant || maintenance of gene silencing variant || organism metabolism processing variant || mRNA export variant || RNA expression variant || sick || late larval arrest |
| Tubulin C-terminal domain-like | 0.1696 | INHERITED FROM: gene expression variant || protein interaction variant || transgene expression variant || protein aggregation variant || mechanosensation variant || nicotine response variant || protein protein interaction variant || organism metabolism processing variant || transgene subcellular localization variant || miRNA expression variant || touch resistant |
| WW domain | 0.1696 | INHERITED FROM: gene expression variant || aldicarb resistant || acetylcholinesterase inhibitor resistant |
| NAD(P)-binding Rossmann-fold domains | 0.1726 | INHERITED FROM: pheromone induced dauer formation variant |
| Tubulin nucleotide-binding domain-like | 0.1908 | INHERITED FROM: gene expression variant || protein interaction variant || transgene expression variant || protein aggregation variant || mechanosensation variant || nicotine response variant || protein protein interaction variant || organism metabolism processing variant || organism environmental stimulus response variant || transgene subcellular localization variant || miRNA expression variant || touch resistant |
| Acid proteases | 0.1908 | INHERITED FROM: gene expression variant || protein interaction variant || transgene expression variant || protein aggregation variant || protein protein interaction variant || organism metabolism processing variant || hypoosmotic shock hypersensitive || pattern of transgene expression variant || transgene subcellular localization variant || osmotic integrity variant |
| Multidrug resistance efflux transporter EmrE | 0.1908 | INHERITED FROM: pathogen resistance increased || bacterially unswollen || organism pathogen response variant |
| Nicotinic receptor ligand binding domain-like | 0.2091 | INHERITED FROM: positive chemotaxis variant || aqueous chemosensory response variant || cholinergic agonist resistant || antihelmintic response variant || nicotine resistant || mechanosensation variant || enhanced taste aversion defective || hypoosmotic shock hypersensitive || organism environmental stimulus response variant || sodium chloride chemotaxis variant || chemical response variant || DMPP response variant |
| Nucleotide cyclase | 0.2121 | INHERITED FROM: positive chemotaxis variant || carbon dioxide response variant || bromide chemotaxis defective || anion positive chemotaxis variant || metabolic pathway variant || second messenger mediated signaling variant || iodide chemotaxis variant || AWC odorant chemotaxis variant || anion positive chemotaxis defective || cation positive chemotaxis defective || chemotaxis variant || organism environmental stimulus response variant || cation positive chemotaxis variant || bromide chemotaxis variant || iodide chemotaxis defective || magnesium chemotaxis defective || lithium chemotaxis defective || chemosensory response variant |
| POZ domain | 0.228 | INHERITED FROM: L1 arrest || resistant to protein aggregation induced paralysis || protein aggregation induced paralysis || early larval arrest |
| ABC transporter transmembrane region | 0.2295 | INHERITED FROM: RNAi response variant || cadmium hypersensitive || metal response variant || cadmium response variant |
| Cyclin-like | 0.2334 | INHERITED FROM: protein phosphorylation reduced || protein phosphorylation variant |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.2376 | INHERITED FROM: positive chemotaxis variant || aqueous chemosensory response variant || cholinergic agonist resistant || antihelmintic response variant || nicotine resistant || mechanosensation variant || enhanced taste aversion defective || hypoosmotic shock hypersensitive || organism environmental stimulus response variant || sodium chloride chemotaxis variant || chemical response variant || DMPP response variant |
| Bromodomain | 0.2415 | INHERITED FROM: organism stress response variant || organism UV response variant || sick || organism UV hypersensitive |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0.252 | INHERITED FROM: antimicrobial gene expression variant || aldicarb resistant || growth rate variant || organism environmental stimulus response variant || protein subcellular localization variant || drug induced gene expression variant || organism pathogen response variant || protein expression variant |
| Growth factor receptor domain | 0.2554 | INHERITED FROM: dauer arrest variant || mRNA expression variant |
| SNARE-like | 0.2715 | INHERITED FROM: gene expression variant || aldicarb resistant || transgene expression variant || acetylcholinesterase inhibitor resistant || pattern of transgene expression variant || transgene subcellular localization variant || acetylcholinesterase inhibitor response variant || sick |
| Band 7/SPFH domain | 0.2715 | INHERITED FROM: mechanosensation variant || organism environmental stimulus response variant |
| FYVE/PHD zinc finger | 0.301 | INHERITED FROM: protein methylation variant || organism UV hypersensitive || ectopic expression transgene |
| Translation proteins SH3-like domain | 0.3041 | INHERITED FROM: gene expression variant || transgene expression variant || protein aggregation variant || protein protein interaction variant || organism metabolism processing variant |
| Multidrug efflux transporter AcrB transmembrane domain | 0.3326 | INHERITED FROM: odorant chemosensory response variant || negative chemotaxis variant || embryo osmotic integrity defective early emb |
| Voltage-gated potassium channels | 0.3367 | INHERITED FROM: mechanosensation variant || positive chemotaxis defective || growth rate variant || adrenergic receptor antagonist response variant |
| Cation efflux protein transmembrane domain-like | 0.3414 | INHERITED FROM: cadmium hypersensitive || metal response variant |
| Tropomyosin | 0.3414 | INHERITED FROM: drug resistant |
| Ribosomal protein S5 domain 2-like | 0.3814 | INHERITED FROM: early larval arrest |
| Cysteine-rich domain | 0.3814 | INHERITED FROM: positive chemotaxis variant || antimicrobial gene expression variant || odorant chemosensory response variant || organism metabolism processing variant || odorant positive chemotaxis variant || chemotaxis variant || organism environmental stimulus response variant || protein subcellular localization variant || drug induced gene expression variant || transgene subcellular localization variant || organism pathogen response variant |
| Cysteine proteinases | 0.3822 | INHERITED FROM: protein interaction variant || transgene expression variant || protein aggregation variant || protein protein interaction variant || organism metabolism processing variant || hypoosmotic shock hypersensitive || pattern of transgene expression variant || transgene subcellular localization variant || osmotic integrity variant |
| Regulator of G-protein signaling, RGS | 0.3901 | INHERITED FROM: mechanosensation variant |
| DNase I-like | 0.4278 | INHERITED FROM: protein subcellular localization variant || pattern protein expression variant |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0.4278 | INHERITED FROM: pathogen susceptibility increased || gene expression variant || protein interaction variant || transgene expression variant || protein aggregation variant || protein protein interaction variant || organism metabolism processing variant || cadmium hypersensitive || metal response variant || organism environmental stimulus response variant || pattern of transgene expression variant || transgene subcellular localization variant || cadmium response variant || life span variant || transgene expression increased |
| Myosin rod fragments | 0.4278 | INHERITED FROM: drug resistant |
| HAD-like | 0.4405 | INHERITED FROM: lipid composition variant || nicotine hypersensitive |
| Sm-like ribonucleoproteins | 0.4557 | INHERITED FROM: gene expression variant || transgene expression variant || pattern of transgene expression variant || protein subcellular localization variant || sick || protein expression variant |
| FKBP-like | 0.4616 | INHERITED FROM: gene expression variant || protein interaction variant || transgene expression variant || protein aggregation variant || protein protein interaction variant || organism metabolism processing variant || pattern of transgene expression variant || transgene subcellular localization variant |
| Ligand-binding domain in the NO signalling and Golgi transport | 0.4748 | INHERITED FROM: carbon dioxide response variant || carbon dioxide avoidance variant || organism environmental stimulus response variant |
| HMG-box | 0.4915 | INHERITED FROM: maintenance of gene silencing variant |
| Cytochrome P450 | 0.5159 | INHERITED FROM: cadmium hypersensitive || metal response variant || cadmium response variant |
| Ubiquitin-like | 0.5258 | INHERITED FROM: protein interaction variant || protein aggregation variant || protein protein interaction variant || hypersensitive to protein aggregation induced paralysis |
| Cystine-knot cytokines | 0.5294 | INHERITED FROM: levamisole response variant || nicotine response variant || transgene expression reduced |
| Lipocalins | 0.5508 | INHERITED FROM: fat content variant || lipid metabolism variant || fat content increased |
| SAM/Pointed domain | 0.5592 | INHERITED FROM: aldicarb resistant || drug resistant |
| Chaperone J-domain | 0.567 | INHERITED FROM: gene expression variant || protein interaction variant || transgene expression variant || protein aggregation variant || protein protein interaction variant || organism metabolism processing variant || pattern of transgene expression variant |
| (Phosphotyrosine protein) phosphatases II | 0.5672 | INHERITED FROM: transgene expression reduced |
| PRTase-like | 0.5885 | INHERITED FROM: Fluorouracil resistant || drug response variant || drug resistant |
| Osmotin, thaumatin-like protein | 0.5885 | INHERITED FROM: cadmium hypersensitive || metal response variant || level of transgene expression variant || cadmium response variant || transgene expression reduced |
| Metallo-dependent phosphatases | 0.5987 | INHERITED FROM: antibody staining variant |
| MFS general substrate transporter | 0.6078 | INHERITED FROM: organism high sodium chloride hypersensitive |
| Ribonuclease H-like | 0.6229 | INHERITED FROM: somatic transgene silencing variant || RNAi response variant || maintenance of gene silencing variant || siRNA expression variant || RNA expression variant || endogenous transposase levels increased || 21U RNA expression variant |
| Frizzled cysteine-rich domain | 0.6557 | INHERITED FROM: protein expression variant |
| (Trans)glycosidases | 0.6557 | INHERITED FROM: pathogen susceptibility increased || pathogen load variant || transgene expression reduced |
| Lipovitellin-phosvitin complex, superhelical domain | 0.6557 | INHERITED FROM: life span variant |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0.6557 | INHERITED FROM: life span variant |
| GST C-terminal domain-like | 0.6562 | INHERITED FROM: organism electrophilic stress hypersensitive || enzyme activity variant || organism stress response variant || organism metabolism processing variant || cadmium hypersensitive || metal response variant || organism environmental stimulus response variant || cadmium response variant || enzyme activity reduced |
| SET domain | 0.6805 | INHERITED FROM: somatic transgene silencing variant || RNAi response variant || maintenance of gene silencing variant || antibody staining variant || mRNA levels reduced || protein methylation variant || protein modification variant || spontaneous mutation rate increased || ectopic expression antibody || ectopic expression transgene |
| Class II aaRS and biotin synthetases | 0.6857 | INHERITED FROM: gene expression variant || transgene expression variant || organism metabolism processing variant || transgene expression increased |
| Fibronectin type III | 0.7029 | INHERITED FROM: growth rate variant || organism temperature response variant |
| Galactose-binding domain-like | 0.706 | INHERITED FROM: protein interaction variant || protein aggregation variant || protein protein interaction variant || transgene subcellular localization variant |
| 5' to 3' exonuclease, C-terminal subdomain | 0.7282 | INHERITED FROM: organism stress response variant |
| MIT domain | 0.7282 | INHERITED FROM: protein interaction variant || protein aggregation variant || protein protein interaction variant || transgene subcellular localization variant |
| ADC-like | 0.7282 | INHERITED FROM: protein interaction variant || protein aggregation variant || protein protein interaction variant || transgene subcellular localization variant |
| beta-sandwich domain of Sec23/24 | 0.7282 | INHERITED FROM: transgene subcellular localization variant |
| Acyl-CoA N-acyltransferases (Nat) | 0.7289 | INHERITED FROM: ectopic expression transgene |
| SH3-domain | 0.7559 | INHERITED FROM: organism environmental stimulus response variant || protein expression variant |
| UBC-like | 0.7786 | INHERITED FROM: gene expression variant || protein interaction variant || transgene expression variant || protein aggregation variant || protein protein interaction variant || organism metabolism processing variant || pattern of transgene expression variant || transgene subcellular localization variant |
| Nucleotidylyl transferase | 0.8002 | INHERITED FROM: paraquat resistant || paraquat response variant || pesticide response variant |
| PLP-dependent transferases | 0.8103 | INHERITED FROM: carbon dioxide response variant || carbon dioxide avoidance variant |
| Rhodanese/Cell cycle control phosphatase | 0.8188 | INHERITED FROM: pathogen susceptibility increased |
| alpha/beta-Hydrolases | 0.8443 | INHERITED FROM: acetylcholinesterase activity variant || acetylcholinesterase reduced |
| EF-hand | 0.8565 | INHERITED FROM: protein aggregation variant |
| Insulin-like | 0.8574 | INHERITED FROM: fat content variant || lipid metabolism variant || dauer arrest variant || organism environmental stimulus response variant |
| Immunoglobulin | 0.8625 | INHERITED FROM: growth rate variant || drug response variant |
| PIN domain-like | 0.8691 | INHERITED FROM: organism stress response variant |
| p53-like transcription factors | 0.8706 | INHERITED FROM: gene expression level reduced |
| Ribonuclease PH domain 2-like | 0.9129 | INHERITED FROM: early larval arrest |
| Glucocorticoid receptor-like (DNA-binding domain) | 0.9444 | INHERITED FROM: gene expression level high || SDS sensitive dauer || lipid metabolism variant || chemical hypersensitive || transgene expression undetectable cell specific || dauer resistance to harsh conditions variant || fat content increased |
| Cyclophilin-like | 0.9639 | INHERITED FROM: gene expression variant || protein interaction variant || transgene expression variant || protein aggregation variant || protein protein interaction variant || organism metabolism processing variant || pattern of transgene expression variant || transgene subcellular localization variant |
| Thiolase-like | 0.9667 | INHERITED FROM: fat content variant |
| Bet v1-like | 0.9667 | INHERITED FROM: growth rate variant |
| beta-beta-alpha zinc fingers | 1 | INHERITED FROM: antibody staining reduced || imipramine resistant || inhibitor of serotonin uptake variant || egg laying serotonin resistant || egg laying imipramine resistant |
| Thioredoxin-like | 1 | INHERITED FROM: organism electrophilic stress hypersensitive || organism heat hypersensitive || enzyme activity variant || organism stress response variant || cadmium hypersensitive || metal response variant || enzyme activity reduced |
| Snake toxin-like | 1 | INHERITED FROM: fat content variant || lipid metabolism variant |
| RING/U-box | 1 | INHERITED FROM: gene expression variant || protein interaction variant || transgene expression variant || protein aggregation variant || protein protein interaction variant || organism metabolism processing variant || pattern of transgene expression variant || transgene subcellular localization variant |
| B-box zinc-binding domain | 1 | INHERITED FROM: protein interaction variant || transgene expression variant || protein aggregation variant || protein protein interaction variant || pattern of transgene expression variant || transgene subcellular localization variant |
| Saposin | 1 | INHERITED FROM: transgene expression variant || increased pathogen survival || pathogen load variant || level of transgene expression variant || organism pathogen response variant || transgene expression reduced |
| Nuclear receptor ligand-binding domain | 1 | INHERITED FROM: SDS sensitive dauer || lipid metabolism variant || chemical hypersensitive || dauer resistance to harsh conditions variant || fat content increased |
| F-box domain | 1 | INHERITED FROM: resistant to protein aggregation induced paralysis || protein aggregation induced paralysis |
| Family A G protein-coupled receptor-like | 1 | INHERITED FROM: serotonin induced pumping variant || locomotion rate serotonin variant || organism pathogen response variant || male tail curling serotonin variant || serotonin induced fat reduction variant |
| Leucine zipper domain | 1 | INHERITED FROM: mRNA levels reduced || mRNA expression variant |
| Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
| WGR domain-like | 0 | Direct |
| MIR domain | 0 | Direct |
| R3H domain | 0 | Direct |
| Cdc48 domain 2-like | 0 | Direct |
| Nucleotidyltransferase | 0 | Direct |
| TGS-like | 0 | Direct |
| Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | Direct |
| GYF domain | 0 | Direct |
| Hypothetical protein c14orf129, hspc210 | 0 | Direct |
| Intermediate filament protein, coiled coil region | 0 | Direct |
| Fibrinogen C-terminal domain-like | 0 | Direct |
| GroEL apical domain-like | 0 | Direct |
| GAT-like domain | 0 | Direct |
| SMAD/FHA domain | 0 | Direct |
| SCP-like | 0 | Direct |
| SMAD MH1 domain | 0 | Direct |
| Retrovirus zinc finger-like domains | 0 | Direct |
| Hect, E3 ligase catalytic domain | 0 | Direct |
| Ribosomal protein L10-like | 0 | Direct |
| Second domain of FERM | 0 | Direct |
| Seven-hairpin glycosidases | 0 | Direct |
| Heme-dependent peroxidases | 0 | Direct |
| Cu,Zn superoxide dismutase-like | 0 | Direct |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
| 2Fe-2S ferredoxin-like | 0 | Direct |
| eIF4e-like | 0 | Direct |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
| SIS domain | 0 | Direct |
| Subtilisin-like | 0 | Direct |
| MOSC N-terminal domain-like | 0 | Direct |
| PGBD-like | 0 | Direct |
| PHM/PNGase F | 0 | Direct |
| ArfGap/RecO-like zinc finger | 0 | Direct |
| Bacterial exopeptidase dimerisation domain | 0 | Direct |
| Nucleoporin domain | 0 | Direct |
| Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | Direct |
| Chitinase insertion domain | 0 | Direct |
| ENTH/VHS domain | 0 | Direct |
| Class II aaRS ABD-related | 0 | Direct |
| Carbohydrate phosphatase | 0 | Direct |
| Integrin domains | 0 | Direct |
| Succinyl-CoA synthetase domains | 0 | Direct |
| Alpha-L RNA-binding motif | 0 | Direct |
| LEM domain | 0 | Direct |
| Periplasmic binding protein-like II | 0 | Direct |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | Direct |
| GHMP Kinase, C-terminal domain | 0 | Direct |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
| Aquaporin-like | 0 | Direct |
| PEBP-like | 0 | Direct |
| Pentein | 0 | Direct |
| DNA repair protein MutS, domain III | 0 | Direct |
| Elafin-like | 0 | Direct |
| MgtE membrane domain-like | 0 | Direct |
| Protease propeptides/inhibitors | 0 | Direct |
| L30e-like | 0 | Direct |
| CAD & PB1 domains | 0 | Direct |
| 3-carboxy-cis,cis-mucoante lactonizing enzyme | 0 | Direct |
| CRAL/TRIO N-terminal domain | 0 | Direct |
| Tricorn protease domain 2 | 0 | Direct |
| Polo-box domain | 0 | Direct |
| Citrate synthase | 0 | Direct |
| Calpain large subunit, middle domain (domain III) | 0 | Direct |
| Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | Direct |
| Phosphoglucomutase, first 3 domains | 0 | Direct |
| ARID-like | 0 | Direct |
| PYP-like sensor domain (PAS domain) | 0 | Direct |
| PABC (PABP) domain | 0 | Direct |
| Sec7 domain | 0 | Direct |
| PK beta-barrel domain-like | 0 | Direct |
| BEACH domain | 0 | Direct |
| Ribosomal protein S10 | 0 | Direct |
| Cullin homology domain | 0 | Direct |
| Smc hinge domain | 0 | Direct |
| TK C-terminal domain-like | 0 | Direct |
| PEP carboxykinase-like | 0 | Direct |
| Integrin alpha N-terminal domain | 0 | Direct |
| Activating enzymes of the ubiquitin-like proteins | 0 | Direct |
| Subdomain of clathrin and coatomer appendage domain | 0 | Direct |
| GroEL-intermediate domain like | 0 | Direct |
| Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0 | Direct |
| Tudor/PWWP/MBT | 0 | Direct |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | Direct |
| Hormone receptor domain | 0 | Direct |
| FtsH protease domain-like | 0 | Direct |
| Helical domain of Sec23/24 | 0 | Direct |
| Alkaline phosphatase-like | 0 | Direct |
| FF domain | 0 | Direct |
| Translational machinery components | 0 | Direct |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | Direct |
| Ribokinase-like | 0 | Direct |
| Composite domain of metallo-dependent hydrolases | 0 | Direct |
| Bactericidal permeability-increasing protein, BPI | 0 | Direct |
| Tubby C-terminal domain-like | 0 | Direct |
| ValRS/IleRS/LeuRS editing domain | 0 | Direct |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| HSP40/DnaJ peptide-binding domain | 0 | Direct |
| Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | Direct |
| YbiA-like | 0 | Direct |
| GroEL equatorial domain-like | 0 | Direct |
| F1F0 ATP synthase subunit C | 0 | Direct |
| Sec1/munc18-like (SM) proteins | 0 | Direct |
| Thyroglobulin type-1 domain | 0 | Direct |
| Phosphoglucomutase, C-terminal domain | 0 | Direct |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| DEATH domain | 0 | Direct |
| Annexin | 0 | Direct |
| Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | Direct |
| Surp module (SWAP domain) | 0 | Direct |
| Profilin (actin-binding protein) | 0 | Direct |
| Terpenoid cyclases/Protein prenyltransferases | 0 | Direct |
| Pepsin inhibitor-3 | 0 | Direct |
| Small-conductance potassium channel | 0 | Direct |
| Class I glutamine amidotransferase-like | 0 | Direct |
| Carbon-nitrogen hydrolase | 0 | Direct |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0 | Direct |
| Aminoacid dehydrogenase-like, N-terminal domain | 0 | Direct |
| Cullin repeat-like | 0 | Direct |
| Skp1 dimerisation domain-like | 0 | Direct |
| Cystatin/monellin | 0 | Direct |
| Domain of poly(ADP-ribose) polymerase | 0 | Direct |
| Nop domain | 0 | Direct |
| ThrRS/AlaRS common domain | 0 | Direct |
| Thiamin diphosphate-binding fold (THDP-binding) | 0 | Direct |
| lambda repressor-like DNA-binding domains | 0 | Direct |
| KA1-like | 0 | Direct |
| Ribosomal proteins S24e, L23 and L15e | 0 | Direct |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
| Spectrin repeat | 0 | Direct |
| Galactose oxidase, central domain | 0 | Direct |
| Acid phosphatase/Vanadium-dependent haloperoxidase | 0 | Direct |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
| Ran binding protein zinc finger-like | 0 | Direct |
| L-aspartase-like | 0 | Direct |
| Clc chloride channel | 0 | Direct |
| Heme-dependent catalase-like | 0 | Direct |
| Transducin (heterotrimeric G protein), gamma chain | 0 | Direct |
| Cation efflux protein cytoplasmic domain-like | 0 | Direct |
| beta-lactamase/transpeptidase-like | 0 | Direct |
| SAICAR synthase-like | 0 | Direct |
| Troponin coil-coiled subunits | 0 | Direct |
| LDH C-terminal domain-like | 0 | Direct |
| PAP/OAS1 substrate-binding domain | 0 | Direct |
| Zn-binding ribosomal proteins | 0 | Direct |
| ISP domain | 0 | Direct |
| Zn-finger domain of Sec23/24 | 0 | Direct |
| Blood coagulation inhibitor (disintegrin) | 0 | Direct |
| Rap/Ran-GAP | 0 | Direct |
| ADP-ribosylation | 0 | Direct |
| PEP carboxykinase N-terminal domain | 0 | Direct |
| Glycolipid transfer protein, GLTP | 0 | Direct |
| Hedgehog/intein (Hint) domain | 0 | Direct |
| FAD-dependent thiol oxidase | 0 | Direct |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | Direct |
| Clathrin adaptor appendage domain | 0 | Direct |
| DNA ligase/mRNA capping enzyme, catalytic domain | 0 | Direct |
| Type II DNA topoisomerase | 0 | Direct |
| Proton glutamate symport protein | 0 | Direct |
| MFPT repeat-like | 0 | Direct |
| Oxysterol-binding protein-like | 0 | Direct |
| Cadherin-like | 0 | Direct |
| PLC-like phosphodiesterases | 0 | Direct |
| Ferritin-like | 0 | Direct |
| Doublecortin (DC) | 0 | Direct |
| Restriction endonuclease-like | 0 | Direct |
| JAB1/MPN domain | 0 | Direct |
| ALDH-like | 0 | Direct |
| Formate/glycerate dehydrogenase catalytic domain-like | 0 | Direct |
| Sec63 N-terminal domain-like | 0 | Direct |
| Phosphoenolpyruvate/pyruvate domain | 0 | Direct |
| SAND domain-like | 0 | Direct |
| cAMP-binding domain-like | 0 | Direct |
| DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
| YWTD domain | 0 | Direct |
| Arginase/deacetylase | 0 | Direct |
| Carboxypeptidase regulatory domain-like | 0 | Direct |
| Tim10-like | 0 | Direct |
| Transducin (alpha subunit), insertion domain | 0 | Direct |
| SPOC domain-like | 0 | Direct |
| Riboflavin synthase domain-like | 0 | Direct |
| Flavoproteins | 0 | Direct |
| Mitochondrial carrier | 0 | Direct |
| dsRNA-binding domain-like | 0 | Direct |
| S-adenosylmethionine synthetase | 0 | Direct |
| Cytochrome c | 0 | Direct |
| Lamin A/C globular tail domain | 0 | Direct |
| P-loop containing nucleoside triphosphate hydrolases | 1.788e-05 | Direct |
| Protein kinase-like (PK-like) | 0.0003731 | Direct |
| WD40 repeat-like | 0.002118 | Inherited |
| PapD-like | 0.002254 | Inherited |
| Histone-fold | 0.002254 | Inherited |
| PH domain-like | 0.002288 | Inherited |
| PDZ domain-like | 0.007977 | Inherited |
| Periplasmic binding protein-like I | 0.009048 | Inherited |
| TPR-like | 0.01321 | Inherited |
| Actin-like ATPase domain | 0.01902 | Inherited |
| "Winged helix" DNA-binding domain | 0.03984 | Inherited |
| SH2 domain | 0.04492 | Inherited |
| Homeodomain-like | 0.05608 | Inherited |
| ARM repeat | 0.06272 | Inherited |
| PAZ domain | 0.07326 | Inherited |
| HLH, helix-loop-helix DNA-binding domain | 0.07394 | Inherited |
| CCCH zinc finger | 0.09337 | Inherited |
| HSP20-like chaperones | 0.09337 | Inherited |
| Nucleic acid-binding proteins | 0.0966 | Inherited |
| Calcium ATPase, transmembrane domain M | 0.1053 | Inherited |
| Translation proteins | 0.1053 | Inherited |
| RNI-like | 0.1101 | Inherited |
| Ankyrin repeat | 0.1171 | Inherited |
| Metal cation-transporting ATPase, ATP-binding domain N | 0.1187 | Inherited |
| Chromo domain-like | 0.1187 | Inherited |
| EGF/Laminin | 0.1295 | Inherited |
| Calcium ATPase, transduction domain A | 0.1338 | Inherited |
| Quinoprotein alcohol dehydrogenase-like | 0.1508 | Inherited |
| RNA-binding domain, RBD | 0.1623 | Inherited |
| Tubulin C-terminal domain-like | 0.1696 | Inherited |
| WW domain | 0.1696 | Inherited |
| NAD(P)-binding Rossmann-fold domains | 0.1726 | Inherited |
| Tubulin nucleotide-binding domain-like | 0.1908 | Inherited |
| Acid proteases | 0.1908 | Inherited |
| Multidrug resistance efflux transporter EmrE | 0.1908 | Inherited |
| Nicotinic receptor ligand binding domain-like | 0.2091 | Inherited |
| Nucleotide cyclase | 0.2121 | Inherited |
| POZ domain | 0.228 | Inherited |
| ABC transporter transmembrane region | 0.2295 | Inherited |
| Cyclin-like | 0.2334 | Inherited |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.2376 | Inherited |
| Bromodomain | 0.2415 | Inherited |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0.252 | Inherited |
| Growth factor receptor domain | 0.2554 | Inherited |
| SNARE-like | 0.2715 | Inherited |
| Band 7/SPFH domain | 0.2715 | Inherited |
| FYVE/PHD zinc finger | 0.301 | Inherited |
| Translation proteins SH3-like domain | 0.3041 | Inherited |
| Multidrug efflux transporter AcrB transmembrane domain | 0.3326 | Inherited |
| Voltage-gated potassium channels | 0.3367 | Inherited |
| Cation efflux protein transmembrane domain-like | 0.3414 | Inherited |
| Tropomyosin | 0.3414 | Inherited |
| Ribosomal protein S5 domain 2-like | 0.3814 | Inherited |
| Cysteine-rich domain | 0.3814 | Inherited |
| Cysteine proteinases | 0.3822 | Inherited |
| Regulator of G-protein signaling, RGS | 0.3901 | Inherited |
| DNase I-like | 0.4278 | Inherited |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0.4278 | Inherited |
| Myosin rod fragments | 0.4278 | Inherited |
| HAD-like | 0.4405 | Inherited |
| Sm-like ribonucleoproteins | 0.4557 | Inherited |
| FKBP-like | 0.4616 | Inherited |
| Ligand-binding domain in the NO signalling and Golgi transport | 0.4748 | Inherited |
| HMG-box | 0.4915 | Inherited |
| Cytochrome P450 | 0.5159 | Inherited |
| Ubiquitin-like | 0.5258 | Inherited |
| Cystine-knot cytokines | 0.5294 | Inherited |
| Lipocalins | 0.5508 | Inherited |
| SAM/Pointed domain | 0.5592 | Inherited |
| Chaperone J-domain | 0.567 | Inherited |
| (Phosphotyrosine protein) phosphatases II | 0.5672 | Inherited |
| PRTase-like | 0.5885 | Inherited |
| Osmotin, thaumatin-like protein | 0.5885 | Inherited |
| Metallo-dependent phosphatases | 0.5987 | Inherited |
| MFS general substrate transporter | 0.6078 | Inherited |
| Ribonuclease H-like | 0.6229 | Inherited |
| Frizzled cysteine-rich domain | 0.6557 | Inherited |
| (Trans)glycosidases | 0.6557 | Inherited |
| Lipovitellin-phosvitin complex, superhelical domain | 0.6557 | Inherited |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0.6557 | Inherited |
| GST C-terminal domain-like | 0.6562 | Inherited |
| SET domain | 0.6805 | Inherited |
| Class II aaRS and biotin synthetases | 0.6857 | Inherited |
| Fibronectin type III | 0.7029 | Inherited |
| Galactose-binding domain-like | 0.706 | Inherited |
| 5' to 3' exonuclease, C-terminal subdomain | 0.7282 | Inherited |
| MIT domain | 0.7282 | Inherited |
| ADC-like | 0.7282 | Inherited |
| beta-sandwich domain of Sec23/24 | 0.7282 | Inherited |
| Acyl-CoA N-acyltransferases (Nat) | 0.7289 | Inherited |
| SH3-domain | 0.7559 | Inherited |
| UBC-like | 0.7786 | Inherited |
| Nucleotidylyl transferase | 0.8002 | Inherited |
| PLP-dependent transferases | 0.8103 | Inherited |
| Rhodanese/Cell cycle control phosphatase | 0.8188 | Inherited |
| alpha/beta-Hydrolases | 0.8443 | Inherited |
| EF-hand | 0.8565 | Inherited |
| Insulin-like | 0.8574 | Inherited |
| Immunoglobulin | 0.8625 | Inherited |
| PIN domain-like | 0.8691 | Inherited |
| p53-like transcription factors | 0.8706 | Inherited |
| Ribonuclease PH domain 2-like | 0.9129 | Inherited |
| Glucocorticoid receptor-like (DNA-binding domain) | 0.9444 | Inherited |
| Cyclophilin-like | 0.9639 | Inherited |
| Thiolase-like | 0.9667 | Inherited |
| Bet v1-like | 0.9667 | Inherited |
| beta-beta-alpha zinc fingers | 1 | Inherited |
| Thioredoxin-like | 1 | Inherited |
| Snake toxin-like | 1 | Inherited |
| RING/U-box | 1 | Inherited |
| B-box zinc-binding domain | 1 | Inherited |
| Saposin | 1 | Inherited |
| Nuclear receptor ligand-binding domain | 1 | Inherited |
| F-box domain | 1 | Inherited |
| Family A G protein-coupled receptor-like | 1 | Inherited |
| Leucine zipper domain | 1 | Inherited |
(show details)
Supra-domains annotated to this WP term (Not in SPWP)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
53187,49464
53187 - Zn-dependent exopeptidases
49464 - Carboxypeptidase regulatory domain-like | 0 | DIRECT |
55973,55973
55973 - S-adenosylmethionine synthetase
55973 - S-adenosylmethionine synthetase | 0 | DIRECT |
52518,52922
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52922 - TK C-terminal domain-like | 0 | DIRECT |
141673,50800
141673 - MOSC N-terminal domain-like
50800 - PK beta-barrel domain-like | 0 | DIRECT |
55394,55394
55394 - Bactericidal permeability-increasing protein, BPI
55394 - Bactericidal permeability-increasing protein, BPI | 0 | DIRECT |
101690,53098
101690 - PAZ domain
53098 - Ribonuclease H-like | 0 | DIRECT |
81698,81698
81698 - FF domain
81698 - FF domain | 0 | DIRECT |
161111,160240
161111 - Cation efflux protein transmembrane domain-like
160240 - Cation efflux protein cytoplasmic domain-like | 0 | DIRECT |
57863,48403
57863 - ArfGap/RecO-like zinc finger
48403 - Ankyrin repeat | 0 | DIRECT |
55681,52954
55681 - Class II aaRS and biotin synthetases
52954 - Class II aaRS ABD-related | 0 | DIRECT |
81301,81631
81301 - Nucleotidyltransferase
81631 - PAP/OAS1 substrate-binding domain | 0 | DIRECT |
51735,55347
51735 - NAD(P)-binding Rossmann-fold domains
55347 - Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | DIRECT |
56672,100879
56672 - DNA/RNA polymerases
100879 - Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
57756,57756
57756 - Retrovirus zinc finger-like domains
57756 - Retrovirus zinc finger-like domains | 0 | DIRECT |
50677,52374
50677 - ValRS/IleRS/LeuRS editing domain
52374 - Nucleotidylyl transferase | 0 | DIRECT |
82615,82615
82615 - Polo-box domain
82615 - Polo-box domain | 0 | DIRECT |
64356,49447
64356 - SNARE-like
49447 - Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
57196,63825
57196 - EGF/Laminin
63825 - YWTD domain | 0 | DIRECT |
54534,54534
54534 - FKBP-like
54534 - FKBP-like | 0 | DIRECT |
100920,100934
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
51735,56327
51735 - NAD(P)-binding Rossmann-fold domains
56327 - LDH C-terminal domain-like | 0 | DIRECT |
50692,54585
50692 - ADC-like
54585 - Cdc48 domain 2-like | 0 | DIRECT |
51905,56425
51905 - FAD/NAD(P)-binding domain
56425 - Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | DIRECT |
47473,51695
47473 - EF-hand
51695 - PLC-like phosphodiesterases | 0 | DIRECT |
57184,57196
57184 - Growth factor receptor domain
57196 - EGF/Laminin | 0 | DIRECT |
55486,50923
55486 - Metalloproteases ("zincins"), catalytic domain
50923 - Hemopexin-like domain | 0 | DIRECT |
55785,55785
55785 - PYP-like sensor domain (PAS domain)
55785 - PYP-like sensor domain (PAS domain) | 0 | DIRECT |
47473,103506
47473 - EF-hand
103506 - Mitochondrial carrier | 0 | DIRECT |
52540,81271
52540 - P-loop containing nucleoside triphosphate hydrolases
81271 - TGS-like | 0 | DIRECT |
54768,54768
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like | 0 | DIRECT |
81324,81327
81324 - Voltage-gated potassium channels
81327 - Small-conductance potassium channel | 0 | DIRECT |
141739,141739
141739 - MFPT repeat-like
141739 - MFPT repeat-like | 0 | DIRECT |
46938,52087
46938 - CRAL/TRIO N-terminal domain
52087 - CRAL/TRIO domain | 0 | DIRECT |
51445,54556
51445 - (Trans)glycosidases
54556 - Chitinase insertion domain | 0 | DIRECT |
57414,57414
57414 - Hairpin loop containing domain-like
57414 - Hairpin loop containing domain-like | 0 | DIRECT |
48452,48452
48452 - TPR-like
48452 - TPR-like | 0 | DIRECT |
56112,82615
56112 - Protein kinase-like (PK-like)
82615 - Polo-box domain | 0 | DIRECT |
50156,50044
50156 - PDZ domain-like
50044 - SH3-domain | 0 | DIRECT |
57196,49899
57196 - EGF/Laminin
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
57756,50630
57756 - Retrovirus zinc finger-like domains
50630 - Acid proteases | 0 | DIRECT |
51556,51338
51556 - Metallo-dependent hydrolases
51338 - Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
51695,49562
51695 - PLC-like phosphodiesterases
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
51206,51206
51206 - cAMP-binding domain-like
51206 - cAMP-binding domain-like | 0 | DIRECT |
81324,81296
81324 - Voltage-gated potassium channels
81296 - E set domains | 0 | DIRECT |
54495,46934
54495 - UBC-like
46934 - UBA-like | 0 | DIRECT |
52540,46785
52540 - P-loop containing nucleoside triphosphate hydrolases
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
57196,57184
57196 - EGF/Laminin
57184 - Growth factor receptor domain | 0 | DIRECT |
81333,81333
81333 - F1F0 ATP synthase subunit C
81333 - F1F0 ATP synthase subunit C | 0 | DIRECT |
51338,51556
51338 - Composite domain of metallo-dependent hydrolases
51556 - Metallo-dependent hydrolases | 0 | DIRECT |
74650,51445
74650 - Galactose mutarotase-like
51445 - (Trans)glycosidases | 0 | DIRECT |
55729,55729
55729 - Acyl-CoA N-acyltransferases (Nat)
55729 - Acyl-CoA N-acyltransferases (Nat) | 0 | DIRECT |
56112,48371
56112 - Protein kinase-like (PK-like)
48371 - ARM repeat | 0 | DIRECT |
51735,50129
51735 - NAD(P)-binding Rossmann-fold domains
50129 - GroES-like | 0 | DIRECT |
48425,50729
48425 - Sec7 domain
50729 - PH domain-like | 0 | DIRECT |
56059,52210
56059 - Glutathione synthetase ATP-binding domain-like
52210 - Succinyl-CoA synthetase domains | 0 | DIRECT |
82895,82895
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat | 0 | DIRECT |
52047,48371
52047 - RNI-like
48371 - ARM repeat | 0 | DIRECT |
75632,46785
75632 - Cullin homology domain
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
57889,57889
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0 | DIRECT |
54001,49758
54001 - Cysteine proteinases
49758 - Calpain large subunit, middle domain (domain III) | 0 | DIRECT |
52518,52518
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52518 - Thiamin diphosphate-binding fold (THDP-binding) | 0 | DIRECT |
49562,48371
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat | 0 | DIRECT |
56601,48403
56601 - beta-lactamase/transpeptidase-like
48403 - Ankyrin repeat | 0 | DIRECT |
52047,52047
52047 - RNI-like
52047 - RNI-like | 0 | DIRECT |
51445,51011
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain | 0 | DIRECT |
54849,52029
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0 | DIRECT |
57903,82199
57903 - FYVE/PHD zinc finger
82199 - SET domain | 0 | DIRECT |
52540,90123
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region | 0 | DIRECT |
64593,74853
64593 - Intermediate filament protein, coiled coil region
74853 - Lamin A/C globular tail domain | 0 | DIRECT |
49493,49493
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
50729,47473
50729 - PH domain-like
47473 - EF-hand | 0 | DIRECT |
54236,54236
54236 - Ubiquitin-like
54236 - Ubiquitin-like | 0 | DIRECT |
54160,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
53738,53738
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains | 0 | DIRECT |
48464,89009
48464 - ENTH/VHS domain
89009 - GAT-like domain | 0 | DIRECT |
47587,56399
47587 - Domain of poly(ADP-ribose) polymerase
56399 - ADP-ribosylation | 0 | DIRECT |
74788,75632
74788 - Cullin repeat-like
75632 - Cullin homology domain | 0 | DIRECT |
57889,48350
57889 - Cysteine-rich domain
48350 - GTPase activation domain, GAP | 0 | DIRECT |
144232,82199
144232 - HIT/MYND zinc finger-like
82199 - SET domain | 0 | DIRECT |
52540,47917
52540 - P-loop containing nucleoside triphosphate hydrolases
47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
48403,52151
48403 - Ankyrin repeat
52151 - FabD/lysophospholipase-like | 0 | DIRECT |
48334,52540
48334 - DNA repair protein MutS, domain III
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
81383,50978
81383 - F-box domain
50978 - WD40 repeat-like | 0 | DIRECT |
48592,54849
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like | 0 | DIRECT |
54585,52540
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
51045,51045
51045 - WW domain
51045 - WW domain | 0 | DIRECT |
54160,54160
54160 - Chromo domain-like
54160 - Chromo domain-like | 0 | DIRECT |
47090,55486
47090 - PGBD-like
55486 - Metalloproteases ("zincins"), catalytic domain | 0 | DIRECT |
48179,48179
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | DIRECT |
52540,140990
52540 - P-loop containing nucleoside triphosphate hydrolases
140990 - FtsH protease domain-like | 0 | DIRECT |
47031,50729
47031 - Second domain of FERM
50729 - PH domain-like | 0 | DIRECT |
52743,49785
52743 - Subtilisin-like
49785 - Galactose-binding domain-like | 0 | DIRECT |
50129,51735
50129 - GroES-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
90229,90229
90229 - CCCH zinc finger
90229 - CCCH zinc finger | 0 | DIRECT |
50447,50465
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
57362,57362
57362 - BPTI-like
57362 - BPTI-like | 0 | DIRECT |
57184,57184
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | DIRECT |
49348,55711
49348 - Clathrin adaptor appendage domain
55711 - Subdomain of clathrin and coatomer appendage domain | 0 | DIRECT |
49265,48726
49265 - Fibronectin type III
48726 - Immunoglobulin | 0 | DIRECT |
46966,46966
46966 - Spectrin repeat
46966 - Spectrin repeat | 0 | DIRECT |
68923,53795
68923 - PEP carboxykinase N-terminal domain
53795 - PEP carboxykinase-like | 0 | DIRECT |
54236,47031
54236 - Ubiquitin-like
47031 - Second domain of FERM | 0 | DIRECT |
50249,50249
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
81383,52047
81383 - F-box domain
52047 - RNI-like | 0 | DIRECT |
50729,56112
50729 - PH domain-like
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
55874,54211
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
54211 - Ribosomal protein S5 domain 2-like | 0 | DIRECT |
52113,52113
52113 - BRCT domain
52113 - BRCT domain | 0 | DIRECT |
55486,57552
55486 - Metalloproteases ("zincins"), catalytic domain
57552 - Blood coagulation inhibitor (disintegrin) | 0 | DIRECT |
52374,47323
52374 - Nucleotidylyl transferase
47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
47895,52540
47895 - Transducin (alpha subunit), insertion domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
53187,55031
53187 - Zn-dependent exopeptidases
55031 - Bacterial exopeptidase dimerisation domain | 0 | DIRECT |
63380,52343
63380 - Riboflavin synthase domain-like
52343 - Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | DIRECT |
53738,55957
53738 - Phosphoglucomutase, first 3 domains
55957 - Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
46785,46785
46785 - "Winged helix" DNA-binding domain
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
56091,50249
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
50044,52540
50044 - SH3-domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
47413,46689
47413 - lambda repressor-like DNA-binding domains
46689 - Homeodomain-like | 0 | DIRECT |
54695,81382
54695 - POZ domain
81382 - Skp1 dimerisation domain-like | 0 | DIRECT |
54897,52743
54897 - Protease propeptides/inhibitors
52743 - Subtilisin-like | 0 | DIRECT |
82919,53300
82919 - Zn-finger domain of Sec23/24
53300 - vWA-like | 0 | DIRECT |
81324,53850
81324 - Voltage-gated potassium channels
53850 - Periplasmic binding protein-like II | 0 | DIRECT |
52283,51735
52283 - Formate/glycerate dehydrogenase catalytic domain-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
81811,82754
81811 - Helical domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
50729,50729
50729 - PH domain-like
50729 - PH domain-like | 0 | DIRECT |
57938,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
48371,56112
48371 - ARM repeat
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
161093,161093
161093 - MgtE membrane domain-like
161093 - MgtE membrane domain-like | 0 | DIRECT |
54897,53187
54897 - Protease propeptides/inhibitors
53187 - Zn-dependent exopeptidases | 0 | DIRECT |
49742,49742
49742 - PHM/PNGase F
49742 - PHM/PNGase F | 0 | DIRECT |
57889,50729
57889 - Cysteine-rich domain
50729 - PH domain-like | 0 | DIRECT |
51971,54373
51971 - Nucleotide-binding domain
54373 - FAD-linked reductases, C-terminal domain | 0 | DIRECT |
57903,51197
57903 - FYVE/PHD zinc finger
51197 - Clavaminate synthase-like | 0 | DIRECT |
49313,49313
49313 - Cadherin-like
49313 - Cadherin-like | 0 | DIRECT |
47203,47203
47203 - Acyl-CoA dehydrogenase C-terminal domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
55920,46785
55920 - Creatinase/aminopeptidase
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.005485 | INHERITED FROM: organism stress response variant || organism UV response variant || growth variant || organism environmental stimulus response variant || sick || organism UV hypersensitive |
55550,56112
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0.01902 | INHERITED FROM: aldicarb resistant || acetylcholinesterase inhibitor resistant || acetylcholinesterase inhibitor response variant |
53067,53067
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 0.02757 | INHERITED FROM: pathogen susceptibility increased || protein interaction variant || transgene expression variant || protein aggregation variant || protein protein interaction variant || organism metabolism processing variant || cadmium hypersensitive || cadmium response variant |
56112,55073
56112 - Protein kinase-like (PK-like)
55073 - Nucleotide cyclase | 0.1053 | INHERITED FROM: AWC odorant chemotaxis defective || positive chemotaxis variant || bromide chemotaxis defective || anion positive chemotaxis variant || benzaldehyde chemotaxis variant || iodide chemotaxis variant || positive chemotaxis defective || AWC odorant chemotaxis variant || anion positive chemotaxis defective || cation positive chemotaxis defective || chemotaxis variant || organism environmental stimulus response variant || cation positive chemotaxis variant || bromide chemotaxis variant || iodide chemotaxis defective || magnesium chemotaxis defective || lithium chemotaxis defective || chemical response variant || chemosensory response variant |
56436,56436
56436 - C-type lectin-like
56436 - C-type lectin-like | 0.113 | INHERITED FROM: cadmium hypersensitive || metal response variant || cadmium response variant |
81660,56784
81660 - Metal cation-transporting ATPase, ATP-binding domain N
56784 - HAD-like | 0.1187 | INHERITED FROM: lipid composition variant || drug hypersensitive || nicotine hypersensitive |
52490,55307
52490 - Tubulin nucleotide-binding domain-like
55307 - Tubulin C-terminal domain-like | 0.1908 | INHERITED FROM: gene expression variant || protein interaction variant || transgene expression variant || protein aggregation variant || mechanosensation variant || nicotine response variant || protein protein interaction variant || organism metabolism processing variant || organism environmental stimulus response variant || transgene subcellular localization variant || miRNA expression variant || touch resistant |
56436,49854
56436 - C-type lectin-like
49854 - Spermadhesin, CUB domain | 0.1945 | INHERITED FROM: cadmium hypersensitive || metal response variant || cadmium response variant |
56784,81665
56784 - HAD-like
81665 - Calcium ATPase, transmembrane domain M | 0.2143 | INHERITED FROM: drug response variant || organism environmental stimulus response variant || drug hypersensitive || nicotine hypersensitive |
48371,48371
48371 - ARM repeat
48371 - ARM repeat | 0.2143 | INHERITED FROM: gene expression variant || organism metabolism processing variant |
90123,52540
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.2295 | INHERITED FROM: RNAi response variant || cadmium hypersensitive || metal response variant || cadmium response variant |
63712,90112
63712 - Nicotinic receptor ligand binding domain-like
90112 - Neurotransmitter-gated ion-channel transmembrane pore | 0.2376 | INHERITED FROM: positive chemotaxis variant || aqueous chemosensory response variant || cholinergic agonist resistant || antihelmintic response variant || nicotine resistant || mechanosensation variant || enhanced taste aversion defective || hypoosmotic shock hypersensitive || organism environmental stimulus response variant || sodium chloride chemotaxis variant || chemical response variant || DMPP response variant |
47954,47954
47954 - Cyclin-like
47954 - Cyclin-like | 0.2715 | INHERITED FROM: protein phosphorylation reduced || protein phosphorylation variant |
52540,50447
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins | 0.2715 | INHERITED FROM: gene expression variant || protein phosphorylation increased || transgene expression variant || mRNA levels increased || mRNA levels reduced || level of protein expression variant || protein aggregation variant || protein protein interaction variant || extended life span || protein expression reduced || mRNA expression variant || protein phosphorylation variant || protein modification variant || transgene expression increased || organism oxidative stress response variant |
47473,47473
47473 - EF-hand
47473 - EF-hand | 0.2715 | INHERITED FROM: acetylcholinesterase inhibitor response variant |
50156,50156
50156 - PDZ domain-like
50156 - PDZ domain-like | 0.3041 | INHERITED FROM: protein subcellular localization variant |
50978,50978
50978 - WD40 repeat-like
50978 - WD40 repeat-like | 0.3041 | INHERITED FROM: positive chemotaxis variant || aqueous chemosensory response variant || aqueous positive chemotaxis variant || mechanosensation variant || positive chemotaxis defective || aqueous positive chemotaxis defective || chemotaxis variant || dauer arrest variant || dauer formation variant |
54928,54928
54928 - RNA-binding domain, RBD
54928 - RNA-binding domain, RBD | 0.3311 | INHERITED FROM: gene expression variant || RNA processing variant || late larval arrest |
53067,100920
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0.4278 | INHERITED FROM: pathogen susceptibility increased || gene expression variant || protein interaction variant || transgene expression variant || protein aggregation variant || protein protein interaction variant || organism metabolism processing variant || cadmium hypersensitive || metal response variant || organism environmental stimulus response variant || pattern of transgene expression variant || transgene subcellular localization variant || cadmium response variant || life span variant || transgene expression increased |
52833,47616
52833 - Thioredoxin-like
47616 - GST C-terminal domain-like | 0.5162 | INHERITED FROM: organism electrophilic stress hypersensitive || enzyme activity variant || organism stress response variant || cadmium hypersensitive || metal response variant || organism environmental stimulus response variant || cadmium response variant || paraquat response variant || enzyme activity reduced |
56968,48431
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
48431 - Lipovitellin-phosvitin complex, superhelical domain | 0.6557 | INHERITED FROM: life span variant |
57903,57903
57903 - FYVE/PHD zinc finger
57903 - FYVE/PHD zinc finger | 0.6557 | INHERITED FROM: organism UV response variant || organism environmental stimulus response variant || organism UV hypersensitive |
48431,56968
48431 - Lipovitellin-phosvitin complex, superhelical domain
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions | 0.6557 | INHERITED FROM: life span variant |
57196,57196
57196 - EGF/Laminin
57196 - EGF/Laminin | 0.682 | INHERITED FROM: growth rate variant || protein expression reduced |
57716,48508
57716 - Glucocorticoid receptor-like (DNA-binding domain)
48508 - Nuclear receptor ligand-binding domain | 0.6871 | INHERITED FROM: SDS sensitive dauer || chemical hypersensitive || dauer resistance to harsh conditions variant |
52833,52833
52833 - Thioredoxin-like
52833 - Thioredoxin-like | 0.7371 | INHERITED FROM: protein interaction variant || protein aggregation variant || protein protein interaction variant || pattern of transgene expression variant || transgene subcellular localization variant |
48726,49265
48726 - Immunoglobulin
49265 - Fibronectin type III | 0.7858 | INHERITED FROM: aldicarb resistant || growth rate variant || drug response variant || chemical response variant |
48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin | 0.7898 | INHERITED FROM: growth rate variant |
54211,55666
54211 - Ribosomal protein S5 domain 2-like
55666 - Ribonuclease PH domain 2-like | 0.9129 | INHERITED FROM: early larval arrest |
50044,50044
50044 - SH3-domain
50044 - SH3-domain | 0.953 | INHERITED FROM: drug response variant |
53300,56436
53300 - vWA-like
56436 - C-type lectin-like | 1 | INHERITED FROM: organism pathogen response variant |
57850,57850
57850 - RING/U-box
57850 - RING/U-box | 1 | INHERITED FROM: protein interaction variant || transgene expression variant || protein aggregation variant || protein protein interaction variant || pattern of transgene expression variant || transgene subcellular localization variant |
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
53187,49464
53187 - Zn-dependent exopeptidases
49464 - Carboxypeptidase regulatory domain-like | 0 | Direct |
55973,55973
55973 - S-adenosylmethionine synthetase
55973 - S-adenosylmethionine synthetase | 0 | Direct |
52518,52922
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52922 - TK C-terminal domain-like | 0 | Direct |
141673,50800
141673 - MOSC N-terminal domain-like
50800 - PK beta-barrel domain-like | 0 | Direct |
55394,55394
55394 - Bactericidal permeability-increasing protein, BPI
55394 - Bactericidal permeability-increasing protein, BPI | 0 | Direct |
101690,53098
101690 - PAZ domain
53098 - Ribonuclease H-like | 0 | Direct |
81698,81698
81698 - FF domain
81698 - FF domain | 0 | Direct |
161111,160240
161111 - Cation efflux protein transmembrane domain-like
160240 - Cation efflux protein cytoplasmic domain-like | 0 | Direct |
57863,48403
57863 - ArfGap/RecO-like zinc finger
48403 - Ankyrin repeat | 0 | Direct |
55681,52954
55681 - Class II aaRS and biotin synthetases
52954 - Class II aaRS ABD-related | 0 | Direct |
81301,81631
81301 - Nucleotidyltransferase
81631 - PAP/OAS1 substrate-binding domain | 0 | Direct |
51735,55347
51735 - NAD(P)-binding Rossmann-fold domains
55347 - Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | Direct |
56672,100879
56672 - DNA/RNA polymerases
100879 - Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
57756,57756
57756 - Retrovirus zinc finger-like domains
57756 - Retrovirus zinc finger-like domains | 0 | Direct |
50677,52374
50677 - ValRS/IleRS/LeuRS editing domain
52374 - Nucleotidylyl transferase | 0 | Direct |
82615,82615
82615 - Polo-box domain
82615 - Polo-box domain | 0 | Direct |
64356,49447
64356 - SNARE-like
49447 - Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
57196,63825
57196 - EGF/Laminin
63825 - YWTD domain | 0 | Direct |
54534,54534
54534 - FKBP-like
54534 - FKBP-like | 0 | Direct |
100920,100934
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
51735,56327
51735 - NAD(P)-binding Rossmann-fold domains
56327 - LDH C-terminal domain-like | 0 | Direct |
50692,54585
50692 - ADC-like
54585 - Cdc48 domain 2-like | 0 | Direct |
51905,56425
51905 - FAD/NAD(P)-binding domain
56425 - Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | Direct |
47473,51695
47473 - EF-hand
51695 - PLC-like phosphodiesterases | 0 | Direct |
57184,57196
57184 - Growth factor receptor domain
57196 - EGF/Laminin | 0 | Direct |
55486,50923
55486 - Metalloproteases ("zincins"), catalytic domain
50923 - Hemopexin-like domain | 0 | Direct |
55785,55785
55785 - PYP-like sensor domain (PAS domain)
55785 - PYP-like sensor domain (PAS domain) | 0 | Direct |
47473,103506
47473 - EF-hand
103506 - Mitochondrial carrier | 0 | Direct |
52540,81271
52540 - P-loop containing nucleoside triphosphate hydrolases
81271 - TGS-like | 0 | Direct |
54768,54768
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like | 0 | Direct |
81324,81327
81324 - Voltage-gated potassium channels
81327 - Small-conductance potassium channel | 0 | Direct |
141739,141739
141739 - MFPT repeat-like
141739 - MFPT repeat-like | 0 | Direct |
46938,52087
46938 - CRAL/TRIO N-terminal domain
52087 - CRAL/TRIO domain | 0 | Direct |
51445,54556
51445 - (Trans)glycosidases
54556 - Chitinase insertion domain | 0 | Direct |
57414,57414
57414 - Hairpin loop containing domain-like
57414 - Hairpin loop containing domain-like | 0 | Direct |
48452,48452
48452 - TPR-like
48452 - TPR-like | 0 | Direct |
56112,82615
56112 - Protein kinase-like (PK-like)
82615 - Polo-box domain | 0 | Direct |
50156,50044
50156 - PDZ domain-like
50044 - SH3-domain | 0 | Direct |
57196,49899
57196 - EGF/Laminin
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
57756,50630
57756 - Retrovirus zinc finger-like domains
50630 - Acid proteases | 0 | Direct |
51556,51338
51556 - Metallo-dependent hydrolases
51338 - Composite domain of metallo-dependent hydrolases | 0 | Direct |
51695,49562
51695 - PLC-like phosphodiesterases
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
51206,51206
51206 - cAMP-binding domain-like
51206 - cAMP-binding domain-like | 0 | Direct |
81324,81296
81324 - Voltage-gated potassium channels
81296 - E set domains | 0 | Direct |
54495,46934
54495 - UBC-like
46934 - UBA-like | 0 | Direct |
52540,46785
52540 - P-loop containing nucleoside triphosphate hydrolases
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
57196,57184
57196 - EGF/Laminin
57184 - Growth factor receptor domain | 0 | Direct |
81333,81333
81333 - F1F0 ATP synthase subunit C
81333 - F1F0 ATP synthase subunit C | 0 | Direct |
51338,51556
51338 - Composite domain of metallo-dependent hydrolases
51556 - Metallo-dependent hydrolases | 0 | Direct |
74650,51445
74650 - Galactose mutarotase-like
51445 - (Trans)glycosidases | 0 | Direct |
55729,55729
55729 - Acyl-CoA N-acyltransferases (Nat)
55729 - Acyl-CoA N-acyltransferases (Nat) | 0 | Direct |
56112,48371
56112 - Protein kinase-like (PK-like)
48371 - ARM repeat | 0 | Direct |
51735,50129
51735 - NAD(P)-binding Rossmann-fold domains
50129 - GroES-like | 0 | Direct |
48425,50729
48425 - Sec7 domain
50729 - PH domain-like | 0 | Direct |
56059,52210
56059 - Glutathione synthetase ATP-binding domain-like
52210 - Succinyl-CoA synthetase domains | 0 | Direct |
82895,82895
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat | 0 | Direct |
52047,48371
52047 - RNI-like
48371 - ARM repeat | 0 | Direct |
75632,46785
75632 - Cullin homology domain
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
57889,57889
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0 | Direct |
54001,49758
54001 - Cysteine proteinases
49758 - Calpain large subunit, middle domain (domain III) | 0 | Direct |
52518,52518
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52518 - Thiamin diphosphate-binding fold (THDP-binding) | 0 | Direct |
49562,48371
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat | 0 | Direct |
56601,48403
56601 - beta-lactamase/transpeptidase-like
48403 - Ankyrin repeat | 0 | Direct |
52047,52047
52047 - RNI-like
52047 - RNI-like | 0 | Direct |
51445,51011
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain | 0 | Direct |
54849,52029
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0 | Direct |
57903,82199
57903 - FYVE/PHD zinc finger
82199 - SET domain | 0 | Direct |
52540,90123
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region | 0 | Direct |
64593,74853
64593 - Intermediate filament protein, coiled coil region
74853 - Lamin A/C globular tail domain | 0 | Direct |
49493,49493
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
50729,47473
50729 - PH domain-like
47473 - EF-hand | 0 | Direct |
54236,54236
54236 - Ubiquitin-like
54236 - Ubiquitin-like | 0 | Direct |
54160,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
53738,53738
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains | 0 | Direct |
48464,89009
48464 - ENTH/VHS domain
89009 - GAT-like domain | 0 | Direct |
47587,56399
47587 - Domain of poly(ADP-ribose) polymerase
56399 - ADP-ribosylation | 0 | Direct |
74788,75632
74788 - Cullin repeat-like
75632 - Cullin homology domain | 0 | Direct |
57889,48350
57889 - Cysteine-rich domain
48350 - GTPase activation domain, GAP | 0 | Direct |
144232,82199
144232 - HIT/MYND zinc finger-like
82199 - SET domain | 0 | Direct |
52540,47917
52540 - P-loop containing nucleoside triphosphate hydrolases
47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
48403,52151
48403 - Ankyrin repeat
52151 - FabD/lysophospholipase-like | 0 | Direct |
48334,52540
48334 - DNA repair protein MutS, domain III
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
81383,50978
81383 - F-box domain
50978 - WD40 repeat-like | 0 | Direct |
48592,54849
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like | 0 | Direct |
54585,52540
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
51045,51045
51045 - WW domain
51045 - WW domain | 0 | Direct |
54160,54160
54160 - Chromo domain-like
54160 - Chromo domain-like | 0 | Direct |
47090,55486
47090 - PGBD-like
55486 - Metalloproteases ("zincins"), catalytic domain | 0 | Direct |
48179,48179
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | Direct |
52540,140990
52540 - P-loop containing nucleoside triphosphate hydrolases
140990 - FtsH protease domain-like | 0 | Direct |
47031,50729
47031 - Second domain of FERM
50729 - PH domain-like | 0 | Direct |
52743,49785
52743 - Subtilisin-like
49785 - Galactose-binding domain-like | 0 | Direct |
50129,51735
50129 - GroES-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | Direct |
90229,90229
90229 - CCCH zinc finger
90229 - CCCH zinc finger | 0 | Direct |
50447,50465
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
57362,57362
57362 - BPTI-like
57362 - BPTI-like | 0 | Direct |
57184,57184
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | Direct |
49348,55711
49348 - Clathrin adaptor appendage domain
55711 - Subdomain of clathrin and coatomer appendage domain | 0 | Direct |
49265,48726
49265 - Fibronectin type III
48726 - Immunoglobulin | 0 | Direct |
46966,46966
46966 - Spectrin repeat
46966 - Spectrin repeat | 0 | Direct |
68923,53795
68923 - PEP carboxykinase N-terminal domain
53795 - PEP carboxykinase-like | 0 | Direct |
54236,47031
54236 - Ubiquitin-like
47031 - Second domain of FERM | 0 | Direct |
50249,50249
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins | 0 | Direct |
81383,52047
81383 - F-box domain
52047 - RNI-like | 0 | Direct |
50729,56112
50729 - PH domain-like
56112 - Protein kinase-like (PK-like) | 0 | Direct |
55874,54211
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
54211 - Ribosomal protein S5 domain 2-like | 0 | Direct |
52113,52113
52113 - BRCT domain
52113 - BRCT domain | 0 | Direct |
55486,57552
55486 - Metalloproteases ("zincins"), catalytic domain
57552 - Blood coagulation inhibitor (disintegrin) | 0 | Direct |
52374,47323
52374 - Nucleotidylyl transferase
47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
47895,52540
47895 - Transducin (alpha subunit), insertion domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
53187,55031
53187 - Zn-dependent exopeptidases
55031 - Bacterial exopeptidase dimerisation domain | 0 | Direct |
63380,52343
63380 - Riboflavin synthase domain-like
52343 - Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | Direct |
53738,55957
53738 - Phosphoglucomutase, first 3 domains
55957 - Phosphoglucomutase, C-terminal domain | 0 | Direct |
46785,46785
46785 - "Winged helix" DNA-binding domain
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
56091,50249
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins | 0 | Direct |
50044,52540
50044 - SH3-domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
47413,46689
47413 - lambda repressor-like DNA-binding domains
46689 - Homeodomain-like | 0 | Direct |
54695,81382
54695 - POZ domain
81382 - Skp1 dimerisation domain-like | 0 | Direct |
54897,52743
54897 - Protease propeptides/inhibitors
52743 - Subtilisin-like | 0 | Direct |
82919,53300
82919 - Zn-finger domain of Sec23/24
53300 - vWA-like | 0 | Direct |
81324,53850
81324 - Voltage-gated potassium channels
53850 - Periplasmic binding protein-like II | 0 | Direct |
52283,51735
52283 - Formate/glycerate dehydrogenase catalytic domain-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | Direct |
81811,82754
81811 - Helical domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
50729,50729
50729 - PH domain-like
50729 - PH domain-like | 0 | Direct |
57938,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
48371,56112
48371 - ARM repeat
56112 - Protein kinase-like (PK-like) | 0 | Direct |
161093,161093
161093 - MgtE membrane domain-like
161093 - MgtE membrane domain-like | 0 | Direct |
54897,53187
54897 - Protease propeptides/inhibitors
53187 - Zn-dependent exopeptidases | 0 | Direct |
49742,49742
49742 - PHM/PNGase F
49742 - PHM/PNGase F | 0 | Direct |
57889,50729
57889 - Cysteine-rich domain
50729 - PH domain-like | 0 | Direct |
51971,54373
51971 - Nucleotide-binding domain
54373 - FAD-linked reductases, C-terminal domain | 0 | Direct |
57903,51197
57903 - FYVE/PHD zinc finger
51197 - Clavaminate synthase-like | 0 | Direct |
49313,49313
49313 - Cadherin-like
49313 - Cadherin-like | 0 | Direct |
47203,47203
47203 - Acyl-CoA dehydrogenase C-terminal domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
55920,46785
55920 - Creatinase/aminopeptidase
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.005485 | Inherited |
55550,56112
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0.01902 | Inherited |
53067,53067
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 0.02757 | Inherited |
56112,55073
56112 - Protein kinase-like (PK-like)
55073 - Nucleotide cyclase | 0.1053 | Inherited |
56436,56436
56436 - C-type lectin-like
56436 - C-type lectin-like | 0.113 | Inherited |
81660,56784
81660 - Metal cation-transporting ATPase, ATP-binding domain N
56784 - HAD-like | 0.1187 | Inherited |
52490,55307
52490 - Tubulin nucleotide-binding domain-like
55307 - Tubulin C-terminal domain-like | 0.1908 | Inherited |
56436,49854
56436 - C-type lectin-like
49854 - Spermadhesin, CUB domain | 0.1945 | Inherited |
56784,81665
56784 - HAD-like
81665 - Calcium ATPase, transmembrane domain M | 0.2143 | Inherited |
48371,48371
48371 - ARM repeat
48371 - ARM repeat | 0.2143 | Inherited |
90123,52540
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.2295 | Inherited |
63712,90112
63712 - Nicotinic receptor ligand binding domain-like
90112 - Neurotransmitter-gated ion-channel transmembrane pore | 0.2376 | Inherited |
47954,47954
47954 - Cyclin-like
47954 - Cyclin-like | 0.2715 | Inherited |
52540,50447
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins | 0.2715 | Inherited |
47473,47473
47473 - EF-hand
47473 - EF-hand | 0.2715 | Inherited |
50156,50156
50156 - PDZ domain-like
50156 - PDZ domain-like | 0.3041 | Inherited |
50978,50978
50978 - WD40 repeat-like
50978 - WD40 repeat-like | 0.3041 | Inherited |
54928,54928
54928 - RNA-binding domain, RBD
54928 - RNA-binding domain, RBD | 0.3311 | Inherited |
53067,100920
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0.4278 | Inherited |
52833,47616
52833 - Thioredoxin-like
47616 - GST C-terminal domain-like | 0.5162 | Inherited |
56968,48431
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
48431 - Lipovitellin-phosvitin complex, superhelical domain | 0.6557 | Inherited |
57903,57903
57903 - FYVE/PHD zinc finger
57903 - FYVE/PHD zinc finger | 0.6557 | Inherited |
48431,56968
48431 - Lipovitellin-phosvitin complex, superhelical domain
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions | 0.6557 | Inherited |
57196,57196
57196 - EGF/Laminin
57196 - EGF/Laminin | 0.682 | Inherited |
57716,48508
57716 - Glucocorticoid receptor-like (DNA-binding domain)
48508 - Nuclear receptor ligand-binding domain | 0.6871 | Inherited |
52833,52833
52833 - Thioredoxin-like
52833 - Thioredoxin-like | 0.7371 | Inherited |
48726,49265
48726 - Immunoglobulin
49265 - Fibronectin type III | 0.7858 | Inherited |
48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin | 0.7898 | Inherited |
54211,55666
54211 - Ribosomal protein S5 domain 2-like
55666 - Ribonuclease PH domain 2-like | 0.9129 | Inherited |
50044,50044
50044 - SH3-domain
50044 - SH3-domain | 0.953 | Inherited |
53300,56436
53300 - vWA-like
56436 - C-type lectin-like | 1 | Inherited |
57850,57850
57850 - RING/U-box
57850 - RING/U-box | 1 | Inherited |
(show details)
Supra-domains annotated to this WP term (Not in SPWP)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
57414,57414,57414
57414 - Hairpin loop containing domain-like
57414 - Hairpin loop containing domain-like
57414 - Hairpin loop containing domain-like | 0 | DIRECT |
54585,52540,52540
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
51735,48179,48179
51735 - NAD(P)-binding Rossmann-fold domains
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | DIRECT |
55973,55973,55973
55973 - S-adenosylmethionine synthetase
55973 - S-adenosylmethionine synthetase
55973 - S-adenosylmethionine synthetase | 0 | DIRECT |
48726,49265,48726
48726 - Immunoglobulin
49265 - Fibronectin type III
48726 - Immunoglobulin | 0 | DIRECT |
53067,100920,100934
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
50249,50249,50249
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
46966,46966,46966
46966 - Spectrin repeat
46966 - Spectrin repeat
46966 - Spectrin repeat | 0 | DIRECT |
54160,54160,52540
54160 - Chromo domain-like
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
50044,55550,56112
50044 - SH3-domain
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
48452,48452,48452
48452 - TPR-like
48452 - TPR-like
48452 - TPR-like | 0 | DIRECT |
49899,49899,49899
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
48371,48371,48371
48371 - ARM repeat
48371 - ARM repeat
48371 - ARM repeat | 0 | DIRECT |
57184,57196,57196
57184 - Growth factor receptor domain
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | DIRECT |
56645,47203,47203
56645 - Acyl-CoA dehydrogenase NM domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
50729,47473,51695
50729 - PH domain-like
47473 - EF-hand
51695 - PLC-like phosphodiesterases | 0 | DIRECT |
90123,52540,90123
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region | 0 | DIRECT |
46938,52087,101576
46938 - CRAL/TRIO N-terminal domain
52087 - CRAL/TRIO domain
101576 - Supernatant protein factor (SPF), C-terminal domain | 0 | DIRECT |
49785,49785,49785
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like | 0 | DIRECT |
82895,82895,82895
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat | 0 | DIRECT |
54897,52743,49785
54897 - Protease propeptides/inhibitors
52743 - Subtilisin-like
49785 - Galactose-binding domain-like | 0 | DIRECT |
50156,50044,52540
50156 - PDZ domain-like
50044 - SH3-domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
52058,52058,52058
52058 - L domain-like
52058 - L domain-like
52058 - L domain-like | 0 | DIRECT |
50129,51735,50129
50129 - GroES-like
51735 - NAD(P)-binding Rossmann-fold domains
50129 - GroES-like | 0 | DIRECT |
54160,52540,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
74650,51445,51011
74650 - Galactose mutarotase-like
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain | 0 | DIRECT |
56436,49854,49854
56436 - C-type lectin-like
49854 - Spermadhesin, CUB domain
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
53738,53738,55957
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains
55957 - Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
49313,49313,49313
49313 - Cadherin-like
49313 - Cadherin-like
49313 - Cadherin-like | 0 | DIRECT |
54928,54928,54928
54928 - RNA-binding domain, RBD
54928 - RNA-binding domain, RBD
54928 - RNA-binding domain, RBD | 0 | DIRECT |
54236,47031,50729
54236 - Ubiquitin-like
47031 - Second domain of FERM
50729 - PH domain-like | 0 | DIRECT |
56112,82615,82615
56112 - Protein kinase-like (PK-like)
82615 - Polo-box domain
82615 - Polo-box domain | 0 | DIRECT |
74788,75632,46785
74788 - Cullin repeat-like
75632 - Cullin homology domain
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
52540,52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
50692,54585,52540
50692 - ADC-like
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
48592,54849,52029
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0 | DIRECT |
52540,50447,50465
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
57938,49493,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
53738,53738,53738
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains | 0 | DIRECT |
52540,90123,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
57362,57362,57362
57362 - BPTI-like
57362 - BPTI-like
57362 - BPTI-like | 0 | DIRECT |
49562,48371,56112
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
63411,63411,63411
63411 - LuxS/MPP-like metallohydrolase
63411 - LuxS/MPP-like metallohydrolase
63411 - LuxS/MPP-like metallohydrolase | 0 | DIRECT |
81660,56784,81665
81660 - Metal cation-transporting ATPase, ATP-binding domain N
56784 - HAD-like
81665 - Calcium ATPase, transmembrane domain M | 0.1338 | INHERITED FROM: lipid composition variant || drug response variant || drug hypersensitive || nicotine hypersensitive |
56436,56436,49854
56436 - C-type lectin-like
56436 - C-type lectin-like
49854 - Spermadhesin, CUB domain | 0.3311 | INHERITED FROM: cadmium hypersensitive || metal response variant || cadmium response variant |
53067,53067,100920
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0.4278 | INHERITED FROM: pathogen susceptibility increased || gene expression variant || protein interaction variant || transgene expression variant || protein aggregation variant || protein protein interaction variant || organism metabolism processing variant || cadmium hypersensitive || metal response variant || organism environmental stimulus response variant || pattern of transgene expression variant || transgene subcellular localization variant || cadmium response variant || life span variant || transgene expression increased |
56968,48431,56968
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
48431 - Lipovitellin-phosvitin complex, superhelical domain
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions | 0.6557 | INHERITED FROM: life span variant |
52833,52833,52833
52833 - Thioredoxin-like
52833 - Thioredoxin-like
52833 - Thioredoxin-like | 0.8262 | INHERITED FROM: protein interaction variant || protein aggregation variant || protein protein interaction variant || transgene subcellular localization variant |
57850,57850,57850
57850 - RING/U-box
57850 - RING/U-box
57850 - RING/U-box | 0.8691 | INHERITED FROM: gene expression variant || protein interaction variant || transgene expression variant || protein aggregation variant || protein protein interaction variant || pattern of transgene expression variant || transgene subcellular localization variant |
48726,48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin
48726 - Immunoglobulin | 0.9328 | INHERITED FROM: growth rate variant |
48726,48726,49265
48726 - Immunoglobulin
48726 - Immunoglobulin
49265 - Fibronectin type III | 0.9898 | INHERITED FROM: growth rate variant |
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
57414,57414,57414
57414 - Hairpin loop containing domain-like
57414 - Hairpin loop containing domain-like
57414 - Hairpin loop containing domain-like | 0 | Direct |
54585,52540,52540
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
51735,48179,48179
51735 - NAD(P)-binding Rossmann-fold domains
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | Direct |
55973,55973,55973
55973 - S-adenosylmethionine synthetase
55973 - S-adenosylmethionine synthetase
55973 - S-adenosylmethionine synthetase | 0 | Direct |
48726,49265,48726
48726 - Immunoglobulin
49265 - Fibronectin type III
48726 - Immunoglobulin | 0 | Direct |
53067,100920,100934
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
50249,50249,50249
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins | 0 | Direct |
46966,46966,46966
46966 - Spectrin repeat
46966 - Spectrin repeat
46966 - Spectrin repeat | 0 | Direct |
54160,54160,52540
54160 - Chromo domain-like
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
50044,55550,56112
50044 - SH3-domain
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0 | Direct |
48452,48452,48452
48452 - TPR-like
48452 - TPR-like
48452 - TPR-like | 0 | Direct |
49899,49899,49899
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
48371,48371,48371
48371 - ARM repeat
48371 - ARM repeat
48371 - ARM repeat | 0 | Direct |
57184,57196,57196
57184 - Growth factor receptor domain
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | Direct |
56645,47203,47203
56645 - Acyl-CoA dehydrogenase NM domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
50729,47473,51695
50729 - PH domain-like
47473 - EF-hand
51695 - PLC-like phosphodiesterases | 0 | Direct |
90123,52540,90123
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region | 0 | Direct |
46938,52087,101576
46938 - CRAL/TRIO N-terminal domain
52087 - CRAL/TRIO domain
101576 - Supernatant protein factor (SPF), C-terminal domain | 0 | Direct |
49785,49785,49785
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like | 0 | Direct |
82895,82895,82895
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat | 0 | Direct |
54897,52743,49785
54897 - Protease propeptides/inhibitors
52743 - Subtilisin-like
49785 - Galactose-binding domain-like | 0 | Direct |
50156,50044,52540
50156 - PDZ domain-like
50044 - SH3-domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
52058,52058,52058
52058 - L domain-like
52058 - L domain-like
52058 - L domain-like | 0 | Direct |
50129,51735,50129
50129 - GroES-like
51735 - NAD(P)-binding Rossmann-fold domains
50129 - GroES-like | 0 | Direct |
54160,52540,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
74650,51445,51011
74650 - Galactose mutarotase-like
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain | 0 | Direct |
56436,49854,49854
56436 - C-type lectin-like
49854 - Spermadhesin, CUB domain
49854 - Spermadhesin, CUB domain | 0 | Direct |
53738,53738,55957
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains
55957 - Phosphoglucomutase, C-terminal domain | 0 | Direct |
49313,49313,49313
49313 - Cadherin-like
49313 - Cadherin-like
49313 - Cadherin-like | 0 | Direct |
54928,54928,54928
54928 - RNA-binding domain, RBD
54928 - RNA-binding domain, RBD
54928 - RNA-binding domain, RBD | 0 | Direct |
54236,47031,50729
54236 - Ubiquitin-like
47031 - Second domain of FERM
50729 - PH domain-like | 0 | Direct |
56112,82615,82615
56112 - Protein kinase-like (PK-like)
82615 - Polo-box domain
82615 - Polo-box domain | 0 | Direct |
74788,75632,46785
74788 - Cullin repeat-like
75632 - Cullin homology domain
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
52540,52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
50692,54585,52540
50692 - ADC-like
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
48592,54849,52029
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0 | Direct |
52540,50447,50465
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
57938,49493,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
53738,53738,53738
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains | 0 | Direct |
52540,90123,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
57362,57362,57362
57362 - BPTI-like
57362 - BPTI-like
57362 - BPTI-like | 0 | Direct |
49562,48371,56112
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat
56112 - Protein kinase-like (PK-like) | 0 | Direct |
63411,63411,63411
63411 - LuxS/MPP-like metallohydrolase
63411 - LuxS/MPP-like metallohydrolase
63411 - LuxS/MPP-like metallohydrolase | 0 | Direct |
81660,56784,81665
81660 - Metal cation-transporting ATPase, ATP-binding domain N
56784 - HAD-like
81665 - Calcium ATPase, transmembrane domain M | 0.1338 | Inherited |
56436,56436,49854
56436 - C-type lectin-like
56436 - C-type lectin-like
49854 - Spermadhesin, CUB domain | 0.3311 | Inherited |
53067,53067,100920
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0.4278 | Inherited |
56968,48431,56968
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
48431 - Lipovitellin-phosvitin complex, superhelical domain
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions | 0.6557 | Inherited |
52833,52833,52833
52833 - Thioredoxin-like
52833 - Thioredoxin-like
52833 - Thioredoxin-like | 0.8262 | Inherited |
57850,57850,57850
57850 - RING/U-box
57850 - RING/U-box
57850 - RING/U-box | 0.8691 | Inherited |
48726,48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin
48726 - Immunoglobulin | 0.9328 | Inherited |
48726,48726,49265
48726 - Immunoglobulin
48726 - Immunoglobulin
49265 - Fibronectin type III | 0.9898 | Inherited |
Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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