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Worm Phenotype (WP): organism physiology variant
(show info)
Phenotype Ontology
Like Gene Ontology (GO), phenotypy ontology classifies and organizes gene-mutant/null phenotypic information from the very general at the top to more specific terms in the directed acyclic graph (DAG) by viewing an individual term as a node and its relations to parental terms (allowing for multiple parents) as directed edges. To navigate this hierarchy, we display all parental phenotypic terms to the current phenotypic term of interest ordered by their shortest distances to the current term. Also, only direct children phenotypic terms of the current phenotypic term are listed. Phenotype ontologies we have incorporated are as follows:
- Disease Ontology (DO) Ontology (DO) DO semantically integrates disease and medical vocabularies through extensive cross mapping of DO terms to MeSH, ICD, NCI thesaurus, SNOMED and OMIM.
- Human Phenotype (HP) Ontology (HP) HP captures phenotypic abnormalities that are described in OMIM, along with the corresponding disease-causing genes. It includes three complementary biological concepts: Mode_of_Inheritance (MI), ONset_and_clinical_course (ON), and Phenotypic_Abnormality (PA).
- Mouse Phenotype (MP) Ontology (MP) MP describes phenotypes of the mouse after a specific gene is genetically disrupted. Using it, Mouse Genome Informatics (MGI) provides high-coverate gene-level phenotypes for the mouse.
- Worm Phenotype (WP) Ontology (WP) WP classifies and organizes phenotype descriptions for C. elegans and other nematodes. Using it, WormBase provides primary resource for phenotype annotations for C. elegans.
- Yeast Phenotype (YP) Ontology (YP) Based on YP which is the major contributor to the Ascomycete phenotype ontology, Saccharomyces Genome Database (SGD) provides single mutant phenotypes for every gene in the yeast genome.
- Fly Phenotype (FP) Ontology (FP) FP refers to FlyBase controlled vocabulary. Specifically, a structured controlled vocabulary is used for the annotation of alleles (for their mutagen etc) in FlyBase.
- Fly Anatomy (FA) Ontology (FA) FA is a structured controlled vocabulary of the anatomy of Drosophila melanogaster, used for the description of phenotypes and where a gene is expressed.
- Zebrafish Anatomy (ZA) Ontology (ZA) ZA displays anatomical terms of the zebrafish using standard anatomical nomenclature, together with affected genes.
- Xenopus Anatomy (XA) Ontology (XA) XA represents the lineage of tissues and the timing of development for frogs (Xenopus laevis and Xenopus tropicalis). It is used to annotate Xenopus gene expression patterns and mutant and morphant phenotypes.
- Arabidopsis Plant Ontology (AP) Ontology (AP) As a major contributor to Plant Ontology which describes plant anatomical and morphological structures (AN) and growth and developmental stages (DE), the Arabidopsis Information Resource (TAIR) provides arabidopsis plant ontology annotations for the model higher plant Arabidopsis thaliana.
- Enzyme Commission (EC) Ontology (EC) Each enzyme is allocated a four-digit EC number, the first three digits of which define the reaction catalysed and the fourth of which is a unique identifier (serial number). Each enzyme is also assigned a systematic name that uniquely defines the reaction catalysed.
- DrugBank ATC (DB) Ontology (DB) In the Anatomical Therapeutic Chemical (ATC) classification system, drugs are classified in groups at five different levels according to the organ or system (1st level, anatomical main group) on which they act and their therapeutic (2nd level, therapeutic subgroup), pharmacological (3rd level, pharmacological subgroup) and chemical properties (4th level, chemical subgroup; 5th level, chemical substance). Only drugs in DrugBank are considered.
- UniProtKB KeyWords (KW) Ontology (KW) Keywords in UniProtKB are controlled vocabulary, providing a summary of the entry content and are used to index UniProtKB/Swiss-Prot entries based on 10 categories (the category "Technical term" being excluded here). Each keyword is attributed manually to UniProtKB/Swiss-Prot entries and automatically to UniProtKB/TrEMBL entries (according to specific annotation rules).
- UniProtKB UniPathway (UP) Ontology (UP) UP is a fully manually curated resource for the representation and annotation of metabolic pathways, being used as controlled vocabulary for pathway annotation in UniProtKB.
Structural Domain Phenotype Ontology and its Annotations
Structural Classification of Proteins (SCOP) classifies evolutionary-related domains into Superfamily level and Family level. Using the phenotype ontologies above, we have generated the domain-centric phenotype annotations, and further identified those phenotype terms which are the most informative to annotate SCOP domains. Promisingly, domain-centric phenotypic annotations can serve as an alternative starting point to explore genotype-phenotype relationships. We provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.
- Structural Domain Disease Ontology (DO) Ontology (SDDO) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DO.txt, and the corresponding ontology:SDDO.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Human Phenotype (HP) Ontology (SDHP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2HP.txt, and the corresponding ontology:SDHP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Mouse Phenotype (MP) Ontology (SDMP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2MP.txt, and the corresponding ontology:SDMP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Worm Phenotype (WP) Ontology (SDWP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2WP.txt, and the corresponding ontology:SDWP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Yeast Phenotype (YP) Ontology (SDYP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2YP.txt, and the corresponding ontology:SDYP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Fly Phenotype (FP) Ontology (SDFP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FP.txt, and the corresponding ontology:SDFP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Fly Anatomy (FA) Ontology (SDFA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FA.txt, and the corresponding ontology:SDFA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Zebrafish Anatomy (ZA) Ontology (SDZA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2ZA.txt, and the corresponding ontology:SDZA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Xenopus Anatomy (XA) Ontology (SDXA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2XA.txt, and the corresponding ontology:SDXA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Arabidopsis Plant Ontology (AP) Ontology (SDAP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2AP.txt, and the corresponding ontology:SDAP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Enzyme Commission (EC) Ontology (SDEC) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2EC.txt, and the corresponding ontology:SDEC.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain DrugBank ATC (DB) Ontology (SDDB) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DB.txt, and the corresponding ontology:SDDB.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain UniProtKB KeyWords (KW) Ontology (SDKW) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2KW.txt, and the corresponding ontology:SDKW.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain UniProtKB UniPathway (UP) Ontology (SDUP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2UP.txt, and the corresponding ontology:SDUP.txt) and mysql tables (Domain2PO.sql.gz).
Supra-domain Phenotype Ontology and its Annotations
Although domain-centric annotations hold great promise in describing phenotypic nature of independent domains, most domains themselves may not just work alone. In multi-domain proteins, they may be combined together to form distinct domain architectures. The recombination of the existing domains is considered as one of major driving forces for phenotypic diversificaation. As an extension, we have also generated supra-domain phenotype ontology and its annotations. Compared to domain-centric phenotype ontology and annotations (SCOP domains at the Superfamily level and Family level), this version focuses on supra-domains and individual SCOP domains ONLY at the Superfamily level. Besides, in terms of individual superfamilies, their annotations from the domain-centric version may be different from those from supra-domains version. Depending on your focus, the former should be used for the consideration of both the Superfamily level and Family level, otherwise the latter should be used if you are interested in domain combinations. Also, we provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.
- Supra-domain Domain Disease Ontology (DO) Ontology (SPDO) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DO.txt, and the corresponding ontology:SPDO.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Human Phenotype (HP) Ontology (SPHO) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2HP.txt, and the corresponding ontology:SPHO.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Mouse Phenotype (MP) Ontology (SPMP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2MP.txt, and the corresponding ontology:SPMP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Worm Phenotype (WP) Ontology (SPWP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2WP.txt, and the corresponding ontology:SPWP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Yeast Phenotype (YP) Ontology (SPYP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2YP.txt, and the corresponding ontology:SPYP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Fly Phenotype (FP) Ontology (SPFP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FP.txt, and the corresponding ontology:SPFP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Fly Anatomy (FA) Ontology (SPFA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FA.txt, and the corresponding ontology:SPFA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Zebrafish Anatomy (ZA) Ontology (SPZA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2ZA.txt, and the corresponding ontology:SPZA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Xenopus Anatomy (XA) Ontology (SPXA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2XA.txt, and the corresponding ontology:SPXA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Arabidopsis Plant Ontology (AP) Ontology (SPAP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2AP.txt, and the corresponding ontology:SPAP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Enzyme Commission (EC) Ontology (SPEC) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2EC.txt, and the corresponding ontology:SPEC.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain DrugBank ATC (DB) Ontology (SPDB) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DB.txt, and the corresponding ontology:SPDB.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain UniProtKB KeyWords (KW) Ontology (SPKW) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2KW.txt, and the corresponding ontology:SPKW.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain UniProtKB UniPathway (UP) Ontology (SPUP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2UP.txt, and the corresponding ontology:SPUP.txt) and mysql tables (SP2PO.sql.gz).
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Superfamily(show details)
Superfamily domains annotated to this WP term (Not in SDWP)
Highlighted in gray are those with FDR_all>0.001
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| Galactose mutarotase-like | 0 | DIRECT |
| dsRNA-binding domain-like | 0 | DIRECT |
| Nucleotidyltransferase | 0 | DIRECT |
| Formate/glycerate dehydrogenase catalytic domain-like | 0 | DIRECT |
| LysM domain | 0 | DIRECT |
| SMAD MH1 domain | 0 | DIRECT |
| Integrin alpha N-terminal domain | 0 | DIRECT |
| Lipovitellin-phosvitin complex, superhelical domain | 0 | DIRECT |
| Carboxypeptidase regulatory domain-like | 0 | DIRECT |
| Ferritin-like | 0 | DIRECT |
| Aldolase | 0 | DIRECT |
| Acyl-CoA dehydrogenase NM domain-like | 0 | DIRECT |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | DIRECT |
| Intermediate filament protein, coiled coil region | 0 | DIRECT |
| Clathrin adaptor appendage domain | 0 | DIRECT |
| Nop domain | 0 | DIRECT |
| GAS2 domain-like | 0 | DIRECT |
| SPOC domain-like | 0 | DIRECT |
| PHM/PNGase F | 0 | DIRECT |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
| GroEL apical domain-like | 0 | DIRECT |
| CO dehydrogenase molybdoprotein N-domain-like | 0 | DIRECT |
| Heme-dependent peroxidases | 0 | DIRECT |
| ISP domain | 0 | DIRECT |
| Cadherin-like | 0 | DIRECT |
| Nucleoside diphosphate kinase, NDK | 0 | DIRECT |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
| GYF domain | 0 | DIRECT |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | DIRECT |
| MIR domain | 0 | DIRECT |
| Acid phosphatase/Vanadium-dependent haloperoxidase | 0 | DIRECT |
| Insulin-like | 0 | DIRECT |
| Second domain of FERM | 0 | DIRECT |
| SAICAR synthase-like | 0 | DIRECT |
| PIN domain-like | 0 | DIRECT |
| Integrin domains | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
| SWIB/MDM2 domain | 0 | DIRECT |
| Diaminopimelate epimerase-like | 0 | DIRECT |
| Arginase/deacetylase | 0 | DIRECT |
| Thyroglobulin type-1 domain | 0 | DIRECT |
| Cytochrome c | 0 | DIRECT |
| Clc chloride channel | 0 | DIRECT |
| Mitochondrial carrier | 0 | DIRECT |
| JAB1/MPN domain | 0 | DIRECT |
| HSP20-like chaperones | 0 | DIRECT |
| Sec7 domain | 0 | DIRECT |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | DIRECT |
| BEACH domain | 0 | DIRECT |
| Nucleoporin domain | 0 | DIRECT |
| Cystatin/monellin | 0 | DIRECT |
| Glutathione synthetase ATP-binding domain-like | 0 | DIRECT |
| Putative DNA-binding domain | 0 | DIRECT |
| Chromo domain-like | 0 | DIRECT |
| Ribokinase-like | 0 | DIRECT |
| Phoshotransferase/anion transport protein | 0 | DIRECT |
| PABC (PABP) domain | 0 | DIRECT |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
| Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
| Phosphoenolpyruvate/pyruvate domain | 0 | DIRECT |
| Ribosomal L27 protein-like | 0 | DIRECT |
| Families 57/38 glycoside transferase middle domain | 0 | DIRECT |
| WWE domain | 0 | DIRECT |
| ALDH-like | 0 | DIRECT |
| Pentein | 0 | DIRECT |
| 14-3-3 protein | 0 | DIRECT |
| SCP-like | 0 | DIRECT |
| Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | DIRECT |
| MFPT repeat-like | 0 | DIRECT |
| Activating enzymes of the ubiquitin-like proteins | 0 | DIRECT |
| Transducin (heterotrimeric G protein), gamma chain | 0 | DIRECT |
| Class I glutamine amidotransferase-like | 0 | DIRECT |
| Chaperone J-domain | 0 | DIRECT |
| ARID-like | 0 | DIRECT |
| ADP-ribosylation | 0 | DIRECT |
| Zn-binding ribosomal proteins | 0 | DIRECT |
| Zn-finger domain of Sec23/24 | 0 | DIRECT |
| eIF4e-like | 0 | DIRECT |
| Sec63 N-terminal domain-like | 0 | DIRECT |
| Blood coagulation inhibitor (disintegrin) | 0 | DIRECT |
| Cdc48 domain 2-like | 0 | DIRECT |
| Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0 | DIRECT |
| Surp module (SWAP domain) | 0 | DIRECT |
| Purine and uridine phosphorylases | 0 | DIRECT |
| Helical domain of Sec23/24 | 0 | DIRECT |
| PreATP-grasp domain | 0 | DIRECT |
| PK beta-barrel domain-like | 0 | DIRECT |
| LDH C-terminal domain-like | 0 | DIRECT |
| SAND domain-like | 0 | DIRECT |
| Phosphoglucomutase, first 3 domains | 0 | DIRECT |
| L-aspartase-like | 0 | DIRECT |
| Single hybrid motif | 0 | DIRECT |
| DEATH domain | 0 | DIRECT |
| Class II aaRS ABD-related | 0 | DIRECT |
| Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | DIRECT |
| L30e-like | 0 | DIRECT |
| Fibrinogen C-terminal domain-like | 0 | DIRECT |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
| alpha/beta knot | 0 | DIRECT |
| Outer arm dynein light chain 1 | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
| Polo-box domain | 0 | DIRECT |
| MgtE membrane domain-like | 0 | DIRECT |
| Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
| Tubby C-terminal domain-like | 0 | DIRECT |
| WGR domain-like | 0 | DIRECT |
| DNA repair protein MutS, domain III | 0 | DIRECT |
| PEP carboxykinase N-terminal domain | 0 | DIRECT |
| Molybdenum cofactor-binding domain | 0 | DIRECT |
| Troponin coil-coiled subunits | 0 | DIRECT |
| beta-lactamase/transpeptidase-like | 0 | DIRECT |
| Glycolipid transfer protein, GLTP | 0 | DIRECT |
| Hedgehog/intein (Hint) domain | 0 | DIRECT |
| Aquaporin-like | 0 | DIRECT |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
| HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
| CAD & PB1 domains | 0 | DIRECT |
| PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | DIRECT |
| Isocitrate/Isopropylmalate dehydrogenase-like | 0 | DIRECT |
| Tubulin C-terminal domain-like | 0 | DIRECT |
| FF domain | 0 | DIRECT |
| cAMP-binding domain-like | 0 | DIRECT |
| Thiamin diphosphate-binding fold (THDP-binding) | 0 | DIRECT |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | DIRECT |
| TGS-like | 0 | DIRECT |
| Sec1/munc18-like (SM) proteins | 0 | DIRECT |
| DNA ligase/mRNA capping enzyme, catalytic domain | 0 | DIRECT |
| Profilin (actin-binding protein) | 0 | DIRECT |
| GroEL equatorial domain-like | 0 | DIRECT |
| Citrate synthase | 0 | DIRECT |
| Cu,Zn superoxide dismutase-like | 0 | DIRECT |
| Rudiment single hybrid motif | 0 | DIRECT |
| 3-carboxy-cis,cis-mucoante lactonizing enzyme | 0 | DIRECT |
| Smc hinge domain | 0 | DIRECT |
| Carbon-nitrogen hydrolase | 0 | DIRECT |
| Ribulose-phoshate binding barrel | 0 | DIRECT |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | DIRECT |
| Complement control module/SCR domain | 0 | DIRECT |
| t-snare proteins | 0 | DIRECT |
| Invertebrate chitin-binding proteins | 0 | DIRECT |
| Lamin A/C globular tail domain | 0 | DIRECT |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | DIRECT |
| Hypothetical protein c14orf129, hspc210 | 0 | DIRECT |
| Cullin homology domain | 0 | DIRECT |
| DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
| Subtilisin-like | 0 | DIRECT |
| Oxysterol-binding protein-like | 0 | DIRECT |
| Transducin (alpha subunit), insertion domain | 0 | DIRECT |
| PurM C-terminal domain-like | 0 | DIRECT |
| alpha-catenin/vinculin-like | 0 | DIRECT |
| Terpenoid cyclases/Protein prenyltransferases | 0 | DIRECT |
| Translational machinery components | 0 | DIRECT |
| 2Fe-2S ferredoxin-like | 0 | DIRECT |
| Terpenoid synthases | 0 | DIRECT |
| Kringle-like | 0 | DIRECT |
| Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | DIRECT |
| Bacterial exopeptidase dimerisation domain | 0 | DIRECT |
| Ribosomal protein L10-like | 0 | DIRECT |
| Cullin repeat-like | 0 | DIRECT |
| Annexin | 0 | DIRECT |
| YbiA-like | 0 | DIRECT |
| Proton glutamate symport protein | 0 | DIRECT |
| Creatinase/prolidase N-terminal domain | 0 | DIRECT |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
| Pepsin inhibitor-3 | 0 | DIRECT |
| Domain of poly(ADP-ribose) polymerase | 0 | DIRECT |
| Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | DIRECT |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| ArfGap/RecO-like zinc finger | 0 | DIRECT |
| RBP11-like subunits of RNA polymerase | 0 | DIRECT |
| PEBP-like | 0 | DIRECT |
| Radical SAM enzymes | 0 | DIRECT |
| Ribosomal proteins S24e, L23 and L15e | 0 | DIRECT |
| PAP/OAS1 substrate-binding domain | 0 | DIRECT |
| Ran binding protein zinc finger-like | 0 | DIRECT |
| Doublecortin (DC) | 0 | DIRECT |
| Carbohydrate phosphatase | 0 | DIRECT |
| lambda repressor-like DNA-binding domains | 0 | DIRECT |
| Periplasmic binding protein-like II | 0 | DIRECT |
| ENTH/VHS domain | 0 | DIRECT |
| GroEL-intermediate domain like | 0 | DIRECT |
| Hormone receptor domain | 0 | DIRECT |
| MOSC N-terminal domain-like | 0 | DIRECT |
| PYP-like sensor domain (PAS domain) | 0 | DIRECT |
| PGBD-like | 0 | DIRECT |
| S-adenosylmethionine synthetase | 0 | DIRECT |
| Cation efflux protein cytoplasmic domain-like | 0 | DIRECT |
| VPS9 domain | 0 | DIRECT |
| Ribosomal protein S10 | 0 | DIRECT |
| FtsH protease domain-like | 0 | DIRECT |
| Elafin-like | 0 | DIRECT |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
| HCP-like | 0 | DIRECT |
| Galactose oxidase, central domain | 0 | DIRECT |
| PLC-like phosphodiesterases | 0 | DIRECT |
| ValRS/IleRS/LeuRS editing domain | 0 | DIRECT |
| CBD9-like | 0 | DIRECT |
| Tim10-like | 0 | DIRECT |
| Heme-dependent catalase-like | 0 | DIRECT |
| ThrRS/AlaRS common domain | 0 | DIRECT |
| Subdomain of clathrin and coatomer appendage domain | 0 | DIRECT |
| Spectrin repeat | 0 | DIRECT |
| Small-conductance potassium channel | 0 | DIRECT |
| PUA domain-like | 0 | DIRECT |
| PLP-binding barrel | 0 | DIRECT |
| GroES-like | 0 | DIRECT |
| PEP carboxykinase-like | 0 | DIRECT |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Tubulin nucleotide-binding domain-like | 0 | DIRECT |
| CRAL/TRIO N-terminal domain | 0 | DIRECT |
| Actin-like ATPase domain | 0 | DIRECT |
| Aminoacid dehydrogenase-like, N-terminal domain | 0 | DIRECT |
| HSP90 C-terminal domain | 0 | DIRECT |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0 | DIRECT |
| Skp1 dimerisation domain-like | 0 | DIRECT |
| Succinyl-CoA synthetase domains | 0 | DIRECT |
| FAD-dependent thiol oxidase | 0 | DIRECT |
| R3H domain | 0 | DIRECT |
| Type II DNA topoisomerase | 0 | DIRECT |
| Protease propeptides/inhibitors | 0 | DIRECT |
| Rap/Ran-GAP | 0 | DIRECT |
| LEM domain | 0 | DIRECT |
| TK C-terminal domain-like | 0 | DIRECT |
| YWTD domain | 0 | DIRECT |
| Band 7/SPFH domain | 0 | DIRECT |
| Tricorn protease domain 2 | 0 | DIRECT |
| GAT-like domain | 0 | DIRECT |
| Ribosomal protein L1 | 0 | DIRECT |
| CO dehydrogenase ISP C-domain like | 0 | DIRECT |
| SIS domain | 0 | DIRECT |
| AN1-like Zinc finger | 0 | DIRECT |
| Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
| Thiolase-like | 0 | DIRECT |
| Restriction endonuclease-like | 0 | DIRECT |
| PurM N-terminal domain-like | 0 | DIRECT |
| Chitinase insertion domain | 0 | DIRECT |
| Carbonic anhydrase | 0 | DIRECT |
| F1F0 ATP synthase subunit C | 0 | DIRECT |
| P-loop containing nucleoside triphosphate hydrolases | 0.000000141 | DIRECT |
| PH domain-like | 0.00005045 | DIRECT |
| Histone-fold | 0.0001284 | DIRECT |
| Protein kinase-like (PK-like) | 0.003944 | INHERITED FROM: egg laying response to food variant || second messenger mediated signaling variant || organism osmostic stress hypersensitive || conflicting sensory integration variant || protein subcellular localization variant || chemical response variant || protein phosphorylation variant || kinase activity reduced || aldicarb response variant || alkaline pH chemotaxis variant || life span variant || transgene expression reduced || drug induced gene expression variant || metal response variant || octanol chemotaxis defective || colchicine resistant || protein phosphorylation reduced || anoxia resistant || mechanosensation variant || organism environmental stimulus response variant || lipid synthesis increased || positive chemotaxis variant || protein expression variant || pathogen induced gene expression variant |
| TPR-like | 0.01801 | INHERITED FROM: associative learning variant || light body touch resistant || positive chemotaxis defective || chemotaxis variant |
| Periplasmic binding protein-like I | 0.0197 | INHERITED FROM: bromide chemotaxis variant || second messenger mediated signaling variant || iodide chemotaxis defective || iodide chemotaxis variant || chemical response variant || AWC odorant chemotaxis defective || chemosensory response variant || AWC odorant chemotaxis variant || alkaline pH chemotaxis variant || aqueous chemosensory response variant || memory retention defective || bromide chemotaxis defective || diacetyl chemotaxis variant || lithium chemotaxis defective || response to food variant || chemotaxis variant || aqueous positive chemotaxis variant || benzaldehyde chemotaxis variant || mechanosensation variant || organism environmental stimulus response variant || magnesium chemotaxis defective || carbon dioxide avoidance variant |
| PapD-like | 0.02874 | INHERITED FROM: developmental growth variant || dauer lifespan variant || lipid metabolism variant || larval arrest || dauer lifespan extended || larval growth variant || slow growth || dauer metabolism variant || fat content variant |
| ARM repeat | 0.03447 | INHERITED FROM: sick || organism metabolism processing variant || RNAi response variant || organism hypersensitive ionizing radiation || protein expression variant || gene expression variant |
| SH2 domain | 0.04538 | INHERITED FROM: protein expression reduced || level of protein expression variant || acetylcholinesterase inhibitor resistant || aldicarb resistant || protein expression variant |
| "Winged helix" DNA-binding domain | 0.04721 | INHERITED FROM: protein aggregation variant || organism metabolism processing variant || shortened life span || protein expression increased || protein protein interaction variant || anesthetic response variant || chemical hypersensitive || life span variant || germline transgene silencing variant || paraquat hypersensitive || spontaneous mutation rate increased || protein aggregation induced behavior variant |
| PDZ domain-like | 0.04911 | INHERITED FROM: acetylcholinesterase inhibitor response variant || aldicarb response variant || drug resistant |
| Homeodomain-like | 0.05573 | INHERITED FROM: level of transgene expression variant || imipramine resistant || sexually dimorphic physiology variant || adrenergic receptor antagonist response variant || organism metabolism processing variant || inhibitor of serotonin uptake variant || ectopic expression transgene || growth rate variant || egg laying imipramine resistant || protein degradation variant || carbon dioxide avoidance variant || carbon dioxide response variant |
| WD40 repeat-like | 0.06617 | INHERITED FROM: antimicrobial gene expression variant || osmotic avoidance variant || protein aggregation variant || late larval arrest || organism metabolism processing variant || protein protein interaction variant || early larval arrest || protein aggregation induced behavior variant |
| Nucleic acid-binding proteins | 0.06743 | INHERITED FROM: nonsense mRNA accumulation || hydroxyurea hypersensitive || hypoxia resistant || sick || hydroxyurea response variant || mRNA surveillance defective |
| Calponin-homology domain, CH-domain | 0.06986 | INHERITED FROM: protein degradation variant |
| Acetyl-CoA synthetase-like | 0.06986 | INHERITED FROM: lipid metabolism variant |
| Cyclin-like | 0.07748 | INHERITED FROM: protein phosphorylation variant || protein phosphorylation reduced |
| CCCH zinc finger | 0.08584 | INHERITED FROM: transgene expression variant || mRNA expression ectopic || ectopic expression transgene || gene expression variant |
| Translation proteins | 0.1055 | INHERITED FROM: transgene expression variant || mRNA levels increased || sick || protein aggregation variant || organism metabolism processing variant || proteasome core activity variant || protein protein interaction variant || protein phosphorylation variant || protein phosphorylation increased || gene expression variant |
| Galactose-binding domain-like | 0.109 | INHERITED FROM: protein aggregation variant || protein protein interaction variant || protein interaction variant |
| Nucleotide cyclase | 0.1287 | INHERITED FROM: anion positive chemotaxis variant || bromide chemotaxis variant || second messenger mediated signaling variant || iodide chemotaxis defective || iodide chemotaxis variant || osmotic avoidance variant || AWC odorant chemotaxis defective || chemosensory response variant || AWC odorant chemotaxis variant || alkaline pH chemotaxis variant || bromide chemotaxis defective || diacetyl chemotaxis variant || lithium chemotaxis defective || chemotaxis variant || cation positive chemotaxis variant || organism environmental stimulus response variant || magnesium chemotaxis defective || anion positive chemotaxis defective || positive chemotaxis variant || carbon dioxide response variant || cation positive chemotaxis defective |
| HLH, helix-loop-helix DNA-binding domain | 0.1287 | INHERITED FROM: aqueous positive chemotaxis defective || organism metabolism processing variant || hypoxia response variant || lysine chemotaxis defective || ectopic expression transgene || gene expression level reduced || RNA expression variant || fungal resistance increased || pathogen resistance increased |
| SMAD/FHA domain | 0.1293 | INHERITED FROM: aldicarb response variant |
| Acid proteases | 0.1293 | INHERITED FROM: transgene expression variant || protein aggregation variant || organism metabolism processing variant || protein protein interaction variant || protein interaction variant || transgene subcellular localization variant || hypoosmotic shock hypersensitive || osmotic integrity variant || gene expression variant |
| Calcium ATPase, transmembrane domain M | 0.1431 | INHERITED FROM: nicotine hypersensitive || organism environmental stimulus response variant || lipid composition variant |
| Metal cation-transporting ATPase, ATP-binding domain N | 0.1581 | INHERITED FROM: nicotine hypersensitive || organism environmental stimulus response variant || lipid composition variant |
| Regulator of G-protein signaling, RGS | 0.1581 | INHERITED FROM: chemotaxis variant || negative chemotaxis variant || mechanosensation variant |
| SH3-domain | 0.1677 | INHERITED FROM: protein expression reduced || protein phosphorylation variant || aldicarb response variant || protein expression variant |
| E set domains | 0.1706 | INHERITED FROM: paraquat hypersensitive |
| Calcium ATPase, transduction domain A | 0.1752 | INHERITED FROM: nicotine hypersensitive || organism environmental stimulus response variant |
| EGF/Laminin | 0.1769 | INHERITED FROM: octanol chemotaxis variant || odorant negative chemotaxis defective || negative chemotaxis variant || octanol chemotaxis defective |
| Quinoprotein alcohol dehydrogenase-like | 0.1935 | INHERITED FROM: mRNA levels increased || L2 arrest || hypoxia response variant || mid larval arrest || protein degradation variant |
| Ankyrin repeat | 0.1944 | INHERITED FROM: octanol chemotaxis variant || organism heat response variant || odorant negative chemotaxis defective || chemosensory response variant || chemotaxis variant || octanol chemotaxis defective || mechanosensation variant |
| Multidrug efflux transporter AcrB transmembrane domain | 0.2083 | INHERITED FROM: odorant chemosensory response variant || odorant positive chemotaxis defective || egg integrity defective early emb || positive chemotaxis defective || embryo osmotic integrity defective early emb || chemotaxis variant |
| DBL homology domain (DH-domain) | 0.2134 | INHERITED FROM: bacterially unswollen || aldicarb response variant || organism pathogen response variant || organism environmental stimulus response variant || pathogen resistance increased |
| ClpP/crotonase | 0.2358 | INHERITED FROM: level of transgene expression variant || lipid metabolism variant || fat content variant |
| HMG-box | 0.2358 | INHERITED FROM: transgene expression variant || maintenance of gene silencing variant |
| (Trans)glycosidases | 0.2358 | INHERITED FROM: pathogen load variant || pathogen susceptibility increased |
| Cytochrome P450 | 0.2358 | INHERITED FROM: metal response variant || cadmium response variant |
| POZ domain | 0.2744 | INHERITED FROM: L1 arrest || chemical hypersensitive || early larval arrest || protein aggregation induced behavior variant || resistant to protein aggregation induced paralysis |
| RNA-binding domain, RBD | 0.2857 | INHERITED FROM: no induction of antimicrobial peptide expression after infection || antimicrobial gene expression variant || sick || organism metabolism processing variant || mRNA export variant || RNA processing variant || starvation induced apoptosis variant || alternative splicing variant || RNA expression variant || maintenance of gene silencing variant || innate immune response variant |
| Bromodomain | 0.2864 | INHERITED FROM: drug adaptation variant || sick || acute functional tolerance to alcohol defective || organism UV response variant || anesthetic response variant || ethanol resistant || anesthetic resistant || organism UV hypersensitive |
| 6-phosphogluconate dehydrogenase C-terminal domain-like | 0.2864 | INHERITED FROM: lipid metabolism variant || fat content variant |
| RNI-like | 0.2867 | INHERITED FROM: resistant to protein aggregation induced paralysis |
| Cysteine proteinases | 0.2905 | INHERITED FROM: pattern of transgene expression variant || organism metabolism processing variant || protein protein interaction variant || protein interaction variant || hypoosmotic shock hypersensitive || paraquat hypersensitive || osmotic integrity variant |
| SNARE-like | 0.3151 | INHERITED FROM: pattern of transgene expression variant || transgene expression variant || sick || organism metabolism processing variant || transgene subcellular localization variant || acetylcholinesterase inhibitor resistant || protein metabolism variant || aldicarb resistant || gene expression variant |
| ABC transporter transmembrane region | 0.3167 | INHERITED FROM: RNAi response variant || metal response variant || colchicine hypersensitive || organism environmental stimulus response variant || cadmium response variant |
| Lipocalins | 0.3265 | INHERITED FROM: fat content increased || lipid metabolism variant || paraquat hypersensitive || fat content variant |
| Cation efflux protein transmembrane domain-like | 0.3824 | INHERITED FROM: manganese toxicity resistant || manganese response variant || metal response variant || cadmium hypersensitive |
| Translation proteins SH3-like domain | 0.3824 | INHERITED FROM: transgene expression variant || protein aggregation variant || organism metabolism processing variant || early larval arrest || gene expression variant |
| Nicotinic receptor ligand binding domain-like | 0.3925 | INHERITED FROM: slowing response on food variant || sodium chloride chemotaxis variant || DMPP response variant || chemical response variant || drug response variant || cholinergic agonist resistant || ivermectin response variant || hypoosmotic shock hypersensitive || aqueous chemosensory response variant || mechanosensation variant || organism environmental stimulus response variant || selenium response variant || antihelmintic response variant || nicotine resistant || ivermectin resistant |
| Ubiquitin-like | 0.4097 | INHERITED FROM: heteroplasmy || protein aggregation variant || organism metabolism processing variant || protein protein interaction variant || protein interaction variant |
| Cysteine-rich domain | 0.4246 | INHERITED FROM: antimicrobial gene expression variant || bacterially unswollen || protein subcellular localization variant || odorant chemosensory response variant || organism metabolism processing variant || aldicarb response variant || drug induced gene expression variant || odorant positive chemotaxis variant || organism pathogen response variant || positive chemotaxis variant |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.4303 | INHERITED FROM: slowing response on food variant || sodium chloride chemotaxis variant || DMPP response variant || chemical response variant || drug response variant || cholinergic agonist resistant || ivermectin response variant || hypoosmotic shock hypersensitive || aqueous chemosensory response variant || protein degradation variant || mechanosensation variant || organism environmental stimulus response variant || selenium response variant || antihelmintic response variant || nicotine resistant || positive chemotaxis variant || ivermectin resistant |
| FKBP-like | 0.4318 | INHERITED FROM: pattern of transgene expression variant || protein aggregation variant || protein protein interaction variant || protein interaction variant || transgene subcellular localization variant |
| Class II aaRS and biotin synthetases | 0.4912 | INHERITED FROM: transgene expression variant || hypoxia resistant || organism metabolism processing variant || hypoxia response variant || oxygen response variant || organism environmental stimulus response variant || gene expression variant |
| Myosin rod fragments | 0.5047 | INHERITED FROM: drug resistant |
| DHS-like NAD/FAD-binding domain | 0.5047 | INHERITED FROM: life span variant || protein acetylation variant || protein modification variant |
| PRTase-like | 0.5047 | INHERITED FROM: Fluorouracil resistant || drug resistant |
| Hect, E3 ligase catalytic domain | 0.5047 | INHERITED FROM: pattern of transgene expression variant || transgene expression variant || protein aggregation variant || organism metabolism processing variant || protein protein interaction variant || protein interaction variant || transgene subcellular localization variant || protein aggregation induced behavior variant || gene expression variant |
| BRCT domain | 0.5247 | INHERITED FROM: organism ionizing radiation response variant |
| FYVE/PHD zinc finger | 0.5432 | INHERITED FROM: organism UV response variant || ectopic expression transgene || protein methylation variant || protein modification variant || organism UV hypersensitive |
| Ribosomal protein S5 domain 2-like | 0.5468 | INHERITED FROM: transgene expression variant || early larval arrest |
| Riboflavin synthase domain-like | 0.5541 | INHERITED FROM: pattern protein expression variant |
| Calpain large subunit, middle domain (domain III) | 0.5541 | INHERITED FROM: metabolic pathway variant || protein metabolism variant || protein degradation variant |
| Ferredoxin reductase-like, C-terminal NADP-linked domain | 0.5541 | INHERITED FROM: pattern protein expression variant |
| Cystine-knot cytokines | 0.5572 | INHERITED FROM: levamisole response variant || nicotine response variant |
| Sm-like ribonucleoproteins | 0.5572 | INHERITED FROM: pattern of transgene expression variant || transgene expression variant || sick || organism heat response variant || protein subcellular localization variant || unfolded protein response variant || life span variant || gene expression variant |
| WW domain | 0.5572 | INHERITED FROM: maintenance of gene silencing variant |
| FAD-linked reductases, C-terminal domain | 0.5572 | INHERITED FROM: life span variant |
| Voltage-gated potassium channels | 0.5595 | INHERITED FROM: metabolic pathway variant || adrenergic receptor antagonist response variant || growth rate variant || serotonin response variant || protein metabolism variant || positive chemotaxis defective || protein degradation variant || mechanosensation variant |
| Nucleotidylyl transferase | 0.5811 | INHERITED FROM: hypoxia resistant || paraquat resistant || organism metabolism processing variant || hypoxia response variant || oxygen response variant || transgene expression increased || organism environmental stimulus response variant |
| FAD/NAD(P)-binding domain | 0.5843 | INHERITED FROM: ATP levels variant || ATP levels reduced || life span variant || pesticide response variant |
| SET domain | 0.5934 | INHERITED FROM: ectopic expression antibody || shortened life span || histone methylation variant || dosage compensation variant || somatic transgene silencing variant || RNAi response variant || life span variant || protein methylation variant || maintenance of gene silencing variant || protein modification variant || protein expression variant || spontaneous mutation rate increased |
| Seven-hairpin glycosidases | 0.6041 | INHERITED FROM: protein aggregation variant || protein protein interaction variant || extended life span |
| SAM/Pointed domain | 0.6065 | INHERITED FROM: aldicarb response variant |
| Growth factor receptor domain | 0.6065 | INHERITED FROM: protein degradation variant |
| UBC-like | 0.6173 | INHERITED FROM: pattern of transgene expression variant || sick || protein aggregation variant || late larval arrest || organism metabolism processing variant || protein protein interaction variant || protein interaction variant || transgene subcellular localization variant |
| Multidrug resistance efflux transporter EmrE | 0.6246 | INHERITED FROM: bacterially unswollen || pathogen resistance increased |
| HAD-like | 0.6303 | INHERITED FROM: nicotine hypersensitive |
| Osmotin, thaumatin-like protein | 0.6614 | INHERITED FROM: metal response variant || cadmium response variant || cadmium hypersensitive |
| KA1-like | 0.6614 | INHERITED FROM: RNA expression variant |
| Nucleotide-binding domain | 0.6614 | INHERITED FROM: extended life span || life span variant |
| MFS general substrate transporter | 0.6887 | INHERITED FROM: organism high sodium chloride hypersensitive |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0.6916 | INHERITED FROM: antimicrobial gene expression variant || metabolic pathway variant || protein subcellular localization variant || chemical response variant || aging variant || RNAi response variant || growth rate variant || drug induced gene expression variant || nose touch variant || organism environmental stimulus response variant || drug resistant || protein expression variant |
| Glucocorticoid receptor-like (DNA-binding domain) | 0.6992 | INHERITED FROM: fat content increased || level of transgene expression variant || SDS sensitive dauer || gene expression level reduced || transgene expression reduced || gene expression level high || dauer resistance to harsh conditions variant |
| GST C-terminal domain-like | 0.7144 | INHERITED FROM: enzyme activity variant || organism stress response variant || organism electrophilic stress hypersensitive || enzyme activity reduced || organism heat hypersensitive || organism environmental stimulus response variant || cadmium response variant || cadmium hypersensitive |
| Frizzled cysteine-rich domain | 0.7242 | INHERITED FROM: transgene expression reduced || antibody staining variant |
| 4Fe-4S ferredoxins | 0.7242 | INHERITED FROM: extended life span |
| S15/NS1 RNA-binding domain | 0.7242 | INHERITED FROM: transgene expression increased |
| Ribonuclease H-like | 0.7521 | INHERITED FROM: 21U RNA expression variant || somatic transgene silencing variant || RNAi response variant || siRNA expression variant || RNA expression variant || RNAi enhanced || maintenance of gene silencing variant |
| PAZ domain | 0.7672 | INHERITED FROM: mRNA levels increased || 21U RNA expression variant || somatic transgene silencing variant || RNAi response variant || siRNA expression variant || RNA expression variant || RNAi enhanced || maintenance of gene silencing variant |
| MIT domain | 0.7897 | INHERITED FROM: protein aggregation variant || protein protein interaction variant || protein interaction variant |
| ADC-like | 0.7897 | INHERITED FROM: metabolic pathway variant || protein aggregation variant || protein protein interaction variant || protein interaction variant || protein metabolism variant |
| alpha/beta-Hydrolases | 0.8202 | INHERITED FROM: acetylcholinesterase activity variant || acetylcholinesterase reduced |
| Fibronectin type III | 0.8286 | INHERITED FROM: protein degradation variant |
| Clavaminate synthase-like | 0.8622 | INHERITED FROM: histone methylation variant || life span variant || protein methylation variant || organism temperature response variant |
| EF-hand | 0.8653 | INHERITED FROM: protein aggregation variant || protein interaction variant |
| Leucine zipper domain | 0.8753 | INHERITED FROM: level of transgene expression variant || mRNA levels reduced || pore forming toxin response variant || mRNA expression variant || transgene expression reduced || pathogen susceptibility increased |
| GTPase activation domain, GAP | 0.8836 | INHERITED FROM: protein expression variant |
| UBA-like | 0.8861 | INHERITED FROM: protein aggregation variant || protein protein interaction variant |
| DNA/RNA polymerases | 0.9493 | INHERITED FROM: DNA metabolism variant || DNA repair variant |
| p53-like transcription factors | 0.9541 | INHERITED FROM: level of transgene expression variant || ectopic expression transgene || gene expression level reduced |
| Ribonuclease PH domain 2-like | 0.9646 | INHERITED FROM: early larval arrest |
| Thioredoxin-like | 0.9741 | INHERITED FROM: enzyme activity variant || organism stress response variant || paraquat response variant || organism electrophilic stress hypersensitive || enzyme activity reduced || organism heat hypersensitive || organism environmental stimulus response variant || cadmium hypersensitive |
| Immunoglobulin | 0.9747 | INHERITED FROM: aldicarb response variant || growth rate variant || protein degradation variant |
| Nuclear receptor ligand-binding domain | 0.9791 | INHERITED FROM: fat content increased || level of transgene expression variant || SDS sensitive dauer || lipid metabolism variant || gene expression level reduced || transgene expression reduced || gene expression level high || dauer resistance to harsh conditions variant |
| Saposin | 1 | INHERITED FROM: level of transgene expression variant || pathogen load variant || increased pathogen survival |
| CoA-dependent acyltransferases | 1 | INHERITED FROM: lipid metabolism variant |
| beta-beta-alpha zinc fingers | 1 | INHERITED FROM: imipramine resistant || organism metabolism processing variant || inhibitor of serotonin uptake variant || egg laying imipramine resistant || egg laying serotonin resistant |
| Family A G protein-coupled receptor-like | 1 | INHERITED FROM: serotonin induced pumping variant || serotonin induced fat reduction variant || male tail curling serotonin variant || locomotion rate serotonin variant |
| Eukaryotic type KH-domain (KH-domain type I) | 1 | INHERITED FROM: RNA expression variant |
| Bet v1-like | 1 | INHERITED FROM: growth rate variant |
| B-box zinc-binding domain | 1 | INHERITED FROM: transgene expression variant || protein aggregation variant || organism metabolism processing variant || protein protein interaction variant || protein interaction variant || transgene subcellular localization variant || gene expression variant |
| F-box domain | 1 | INHERITED FROM: resistant to protein aggregation induced paralysis |
| Cyclophilin-like | 1 | INHERITED FROM: pattern of transgene expression variant || transgene expression variant || protein aggregation variant || protein protein interaction variant || protein interaction variant || transgene subcellular localization variant || gene expression variant |
| Ligand-binding domain in the NO signalling and Golgi transport | 1 | INHERITED FROM: carbon dioxide avoidance variant || carbon dioxide response variant |
| RING/U-box | 1 | INHERITED FROM: pattern of transgene expression variant || transgene expression variant || protein aggregation variant || organism metabolism processing variant || protein protein interaction variant || protein interaction variant || transgene subcellular localization variant || gene expression variant |
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| Galactose mutarotase-like | 0 | Direct |
| dsRNA-binding domain-like | 0 | Direct |
| Nucleotidyltransferase | 0 | Direct |
| Formate/glycerate dehydrogenase catalytic domain-like | 0 | Direct |
| LysM domain | 0 | Direct |
| SMAD MH1 domain | 0 | Direct |
| Integrin alpha N-terminal domain | 0 | Direct |
| Lipovitellin-phosvitin complex, superhelical domain | 0 | Direct |
| Carboxypeptidase regulatory domain-like | 0 | Direct |
| Ferritin-like | 0 | Direct |
| Aldolase | 0 | Direct |
| Acyl-CoA dehydrogenase NM domain-like | 0 | Direct |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | Direct |
| Intermediate filament protein, coiled coil region | 0 | Direct |
| Clathrin adaptor appendage domain | 0 | Direct |
| Nop domain | 0 | Direct |
| GAS2 domain-like | 0 | Direct |
| SPOC domain-like | 0 | Direct |
| PHM/PNGase F | 0 | Direct |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
| GroEL apical domain-like | 0 | Direct |
| CO dehydrogenase molybdoprotein N-domain-like | 0 | Direct |
| Heme-dependent peroxidases | 0 | Direct |
| ISP domain | 0 | Direct |
| Cadherin-like | 0 | Direct |
| Nucleoside diphosphate kinase, NDK | 0 | Direct |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
| GYF domain | 0 | Direct |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | Direct |
| MIR domain | 0 | Direct |
| Acid phosphatase/Vanadium-dependent haloperoxidase | 0 | Direct |
| Insulin-like | 0 | Direct |
| Second domain of FERM | 0 | Direct |
| SAICAR synthase-like | 0 | Direct |
| PIN domain-like | 0 | Direct |
| Integrin domains | 0 | Direct |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
| SWIB/MDM2 domain | 0 | Direct |
| Diaminopimelate epimerase-like | 0 | Direct |
| Arginase/deacetylase | 0 | Direct |
| Thyroglobulin type-1 domain | 0 | Direct |
| Cytochrome c | 0 | Direct |
| Clc chloride channel | 0 | Direct |
| Mitochondrial carrier | 0 | Direct |
| JAB1/MPN domain | 0 | Direct |
| HSP20-like chaperones | 0 | Direct |
| Sec7 domain | 0 | Direct |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | Direct |
| BEACH domain | 0 | Direct |
| Nucleoporin domain | 0 | Direct |
| Cystatin/monellin | 0 | Direct |
| Glutathione synthetase ATP-binding domain-like | 0 | Direct |
| Putative DNA-binding domain | 0 | Direct |
| Chromo domain-like | 0 | Direct |
| Ribokinase-like | 0 | Direct |
| Phoshotransferase/anion transport protein | 0 | Direct |
| PABC (PABP) domain | 0 | Direct |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
| Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
| Phosphoenolpyruvate/pyruvate domain | 0 | Direct |
| Ribosomal L27 protein-like | 0 | Direct |
| Families 57/38 glycoside transferase middle domain | 0 | Direct |
| WWE domain | 0 | Direct |
| ALDH-like | 0 | Direct |
| Pentein | 0 | Direct |
| 14-3-3 protein | 0 | Direct |
| SCP-like | 0 | Direct |
| Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | Direct |
| MFPT repeat-like | 0 | Direct |
| Activating enzymes of the ubiquitin-like proteins | 0 | Direct |
| Transducin (heterotrimeric G protein), gamma chain | 0 | Direct |
| Class I glutamine amidotransferase-like | 0 | Direct |
| Chaperone J-domain | 0 | Direct |
| ARID-like | 0 | Direct |
| ADP-ribosylation | 0 | Direct |
| Zn-binding ribosomal proteins | 0 | Direct |
| Zn-finger domain of Sec23/24 | 0 | Direct |
| eIF4e-like | 0 | Direct |
| Sec63 N-terminal domain-like | 0 | Direct |
| Blood coagulation inhibitor (disintegrin) | 0 | Direct |
| Cdc48 domain 2-like | 0 | Direct |
| Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0 | Direct |
| Surp module (SWAP domain) | 0 | Direct |
| Purine and uridine phosphorylases | 0 | Direct |
| Helical domain of Sec23/24 | 0 | Direct |
| PreATP-grasp domain | 0 | Direct |
| PK beta-barrel domain-like | 0 | Direct |
| LDH C-terminal domain-like | 0 | Direct |
| SAND domain-like | 0 | Direct |
| Phosphoglucomutase, first 3 domains | 0 | Direct |
| L-aspartase-like | 0 | Direct |
| Single hybrid motif | 0 | Direct |
| DEATH domain | 0 | Direct |
| Class II aaRS ABD-related | 0 | Direct |
| Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | Direct |
| L30e-like | 0 | Direct |
| Fibrinogen C-terminal domain-like | 0 | Direct |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
| alpha/beta knot | 0 | Direct |
| Outer arm dynein light chain 1 | 0 | Direct |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
| Polo-box domain | 0 | Direct |
| MgtE membrane domain-like | 0 | Direct |
| Composite domain of metallo-dependent hydrolases | 0 | Direct |
| Tubby C-terminal domain-like | 0 | Direct |
| WGR domain-like | 0 | Direct |
| DNA repair protein MutS, domain III | 0 | Direct |
| PEP carboxykinase N-terminal domain | 0 | Direct |
| Molybdenum cofactor-binding domain | 0 | Direct |
| Troponin coil-coiled subunits | 0 | Direct |
| beta-lactamase/transpeptidase-like | 0 | Direct |
| Glycolipid transfer protein, GLTP | 0 | Direct |
| Hedgehog/intein (Hint) domain | 0 | Direct |
| Aquaporin-like | 0 | Direct |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | Direct |
| HSP40/DnaJ peptide-binding domain | 0 | Direct |
| CAD & PB1 domains | 0 | Direct |
| PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | Direct |
| Isocitrate/Isopropylmalate dehydrogenase-like | 0 | Direct |
| Tubulin C-terminal domain-like | 0 | Direct |
| FF domain | 0 | Direct |
| cAMP-binding domain-like | 0 | Direct |
| Thiamin diphosphate-binding fold (THDP-binding) | 0 | Direct |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | Direct |
| TGS-like | 0 | Direct |
| Sec1/munc18-like (SM) proteins | 0 | Direct |
| DNA ligase/mRNA capping enzyme, catalytic domain | 0 | Direct |
| Profilin (actin-binding protein) | 0 | Direct |
| GroEL equatorial domain-like | 0 | Direct |
| Citrate synthase | 0 | Direct |
| Cu,Zn superoxide dismutase-like | 0 | Direct |
| Rudiment single hybrid motif | 0 | Direct |
| 3-carboxy-cis,cis-mucoante lactonizing enzyme | 0 | Direct |
| Smc hinge domain | 0 | Direct |
| Carbon-nitrogen hydrolase | 0 | Direct |
| Ribulose-phoshate binding barrel | 0 | Direct |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | Direct |
| Complement control module/SCR domain | 0 | Direct |
| t-snare proteins | 0 | Direct |
| Invertebrate chitin-binding proteins | 0 | Direct |
| Lamin A/C globular tail domain | 0 | Direct |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | Direct |
| Hypothetical protein c14orf129, hspc210 | 0 | Direct |
| Cullin homology domain | 0 | Direct |
| DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
| Subtilisin-like | 0 | Direct |
| Oxysterol-binding protein-like | 0 | Direct |
| Transducin (alpha subunit), insertion domain | 0 | Direct |
| PurM C-terminal domain-like | 0 | Direct |
| alpha-catenin/vinculin-like | 0 | Direct |
| Terpenoid cyclases/Protein prenyltransferases | 0 | Direct |
| Translational machinery components | 0 | Direct |
| 2Fe-2S ferredoxin-like | 0 | Direct |
| Terpenoid synthases | 0 | Direct |
| Kringle-like | 0 | Direct |
| Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | Direct |
| Bacterial exopeptidase dimerisation domain | 0 | Direct |
| Ribosomal protein L10-like | 0 | Direct |
| Cullin repeat-like | 0 | Direct |
| Annexin | 0 | Direct |
| YbiA-like | 0 | Direct |
| Proton glutamate symport protein | 0 | Direct |
| Creatinase/prolidase N-terminal domain | 0 | Direct |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
| Pepsin inhibitor-3 | 0 | Direct |
| Domain of poly(ADP-ribose) polymerase | 0 | Direct |
| Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | Direct |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| ArfGap/RecO-like zinc finger | 0 | Direct |
| RBP11-like subunits of RNA polymerase | 0 | Direct |
| PEBP-like | 0 | Direct |
| Radical SAM enzymes | 0 | Direct |
| Ribosomal proteins S24e, L23 and L15e | 0 | Direct |
| PAP/OAS1 substrate-binding domain | 0 | Direct |
| Ran binding protein zinc finger-like | 0 | Direct |
| Doublecortin (DC) | 0 | Direct |
| Carbohydrate phosphatase | 0 | Direct |
| lambda repressor-like DNA-binding domains | 0 | Direct |
| Periplasmic binding protein-like II | 0 | Direct |
| ENTH/VHS domain | 0 | Direct |
| GroEL-intermediate domain like | 0 | Direct |
| Hormone receptor domain | 0 | Direct |
| MOSC N-terminal domain-like | 0 | Direct |
| PYP-like sensor domain (PAS domain) | 0 | Direct |
| PGBD-like | 0 | Direct |
| S-adenosylmethionine synthetase | 0 | Direct |
| Cation efflux protein cytoplasmic domain-like | 0 | Direct |
| VPS9 domain | 0 | Direct |
| Ribosomal protein S10 | 0 | Direct |
| FtsH protease domain-like | 0 | Direct |
| Elafin-like | 0 | Direct |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
| HCP-like | 0 | Direct |
| Galactose oxidase, central domain | 0 | Direct |
| PLC-like phosphodiesterases | 0 | Direct |
| ValRS/IleRS/LeuRS editing domain | 0 | Direct |
| CBD9-like | 0 | Direct |
| Tim10-like | 0 | Direct |
| Heme-dependent catalase-like | 0 | Direct |
| ThrRS/AlaRS common domain | 0 | Direct |
| Subdomain of clathrin and coatomer appendage domain | 0 | Direct |
| Spectrin repeat | 0 | Direct |
| Small-conductance potassium channel | 0 | Direct |
| PUA domain-like | 0 | Direct |
| PLP-binding barrel | 0 | Direct |
| GroES-like | 0 | Direct |
| PEP carboxykinase-like | 0 | Direct |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Tubulin nucleotide-binding domain-like | 0 | Direct |
| CRAL/TRIO N-terminal domain | 0 | Direct |
| Actin-like ATPase domain | 0 | Direct |
| Aminoacid dehydrogenase-like, N-terminal domain | 0 | Direct |
| HSP90 C-terminal domain | 0 | Direct |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0 | Direct |
| Skp1 dimerisation domain-like | 0 | Direct |
| Succinyl-CoA synthetase domains | 0 | Direct |
| FAD-dependent thiol oxidase | 0 | Direct |
| R3H domain | 0 | Direct |
| Type II DNA topoisomerase | 0 | Direct |
| Protease propeptides/inhibitors | 0 | Direct |
| Rap/Ran-GAP | 0 | Direct |
| LEM domain | 0 | Direct |
| TK C-terminal domain-like | 0 | Direct |
| YWTD domain | 0 | Direct |
| Band 7/SPFH domain | 0 | Direct |
| Tricorn protease domain 2 | 0 | Direct |
| GAT-like domain | 0 | Direct |
| Ribosomal protein L1 | 0 | Direct |
| CO dehydrogenase ISP C-domain like | 0 | Direct |
| SIS domain | 0 | Direct |
| AN1-like Zinc finger | 0 | Direct |
| Phosphoglucomutase, C-terminal domain | 0 | Direct |
| Thiolase-like | 0 | Direct |
| Restriction endonuclease-like | 0 | Direct |
| PurM N-terminal domain-like | 0 | Direct |
| Chitinase insertion domain | 0 | Direct |
| Carbonic anhydrase | 0 | Direct |
| F1F0 ATP synthase subunit C | 0 | Direct |
| P-loop containing nucleoside triphosphate hydrolases | 0.000000141 | Direct |
| PH domain-like | 0.00005045 | Direct |
| Histone-fold | 0.0001284 | Direct |
| Protein kinase-like (PK-like) | 0.003944 | Inherited |
| TPR-like | 0.01801 | Inherited |
| Periplasmic binding protein-like I | 0.0197 | Inherited |
| PapD-like | 0.02874 | Inherited |
| ARM repeat | 0.03447 | Inherited |
| SH2 domain | 0.04538 | Inherited |
| "Winged helix" DNA-binding domain | 0.04721 | Inherited |
| PDZ domain-like | 0.04911 | Inherited |
| Homeodomain-like | 0.05573 | Inherited |
| WD40 repeat-like | 0.06617 | Inherited |
| Nucleic acid-binding proteins | 0.06743 | Inherited |
| Calponin-homology domain, CH-domain | 0.06986 | Inherited |
| Acetyl-CoA synthetase-like | 0.06986 | Inherited |
| Cyclin-like | 0.07748 | Inherited |
| CCCH zinc finger | 0.08584 | Inherited |
| Translation proteins | 0.1055 | Inherited |
| Galactose-binding domain-like | 0.109 | Inherited |
| Nucleotide cyclase | 0.1287 | Inherited |
| HLH, helix-loop-helix DNA-binding domain | 0.1287 | Inherited |
| SMAD/FHA domain | 0.1293 | Inherited |
| Acid proteases | 0.1293 | Inherited |
| Calcium ATPase, transmembrane domain M | 0.1431 | Inherited |
| Metal cation-transporting ATPase, ATP-binding domain N | 0.1581 | Inherited |
| Regulator of G-protein signaling, RGS | 0.1581 | Inherited |
| SH3-domain | 0.1677 | Inherited |
| E set domains | 0.1706 | Inherited |
| Calcium ATPase, transduction domain A | 0.1752 | Inherited |
| EGF/Laminin | 0.1769 | Inherited |
| Quinoprotein alcohol dehydrogenase-like | 0.1935 | Inherited |
| Ankyrin repeat | 0.1944 | Inherited |
| Multidrug efflux transporter AcrB transmembrane domain | 0.2083 | Inherited |
| DBL homology domain (DH-domain) | 0.2134 | Inherited |
| ClpP/crotonase | 0.2358 | Inherited |
| HMG-box | 0.2358 | Inherited |
| (Trans)glycosidases | 0.2358 | Inherited |
| Cytochrome P450 | 0.2358 | Inherited |
| POZ domain | 0.2744 | Inherited |
| RNA-binding domain, RBD | 0.2857 | Inherited |
| Bromodomain | 0.2864 | Inherited |
| 6-phosphogluconate dehydrogenase C-terminal domain-like | 0.2864 | Inherited |
| RNI-like | 0.2867 | Inherited |
| Cysteine proteinases | 0.2905 | Inherited |
| SNARE-like | 0.3151 | Inherited |
| ABC transporter transmembrane region | 0.3167 | Inherited |
| Lipocalins | 0.3265 | Inherited |
| Cation efflux protein transmembrane domain-like | 0.3824 | Inherited |
| Translation proteins SH3-like domain | 0.3824 | Inherited |
| Nicotinic receptor ligand binding domain-like | 0.3925 | Inherited |
| Ubiquitin-like | 0.4097 | Inherited |
| Cysteine-rich domain | 0.4246 | Inherited |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.4303 | Inherited |
| FKBP-like | 0.4318 | Inherited |
| Class II aaRS and biotin synthetases | 0.4912 | Inherited |
| Myosin rod fragments | 0.5047 | Inherited |
| DHS-like NAD/FAD-binding domain | 0.5047 | Inherited |
| PRTase-like | 0.5047 | Inherited |
| Hect, E3 ligase catalytic domain | 0.5047 | Inherited |
| BRCT domain | 0.5247 | Inherited |
| FYVE/PHD zinc finger | 0.5432 | Inherited |
| Ribosomal protein S5 domain 2-like | 0.5468 | Inherited |
| Riboflavin synthase domain-like | 0.5541 | Inherited |
| Calpain large subunit, middle domain (domain III) | 0.5541 | Inherited |
| Ferredoxin reductase-like, C-terminal NADP-linked domain | 0.5541 | Inherited |
| Cystine-knot cytokines | 0.5572 | Inherited |
| Sm-like ribonucleoproteins | 0.5572 | Inherited |
| WW domain | 0.5572 | Inherited |
| FAD-linked reductases, C-terminal domain | 0.5572 | Inherited |
| Voltage-gated potassium channels | 0.5595 | Inherited |
| Nucleotidylyl transferase | 0.5811 | Inherited |
| FAD/NAD(P)-binding domain | 0.5843 | Inherited |
| SET domain | 0.5934 | Inherited |
| Seven-hairpin glycosidases | 0.6041 | Inherited |
| SAM/Pointed domain | 0.6065 | Inherited |
| Growth factor receptor domain | 0.6065 | Inherited |
| UBC-like | 0.6173 | Inherited |
| Multidrug resistance efflux transporter EmrE | 0.6246 | Inherited |
| HAD-like | 0.6303 | Inherited |
| Osmotin, thaumatin-like protein | 0.6614 | Inherited |
| KA1-like | 0.6614 | Inherited |
| Nucleotide-binding domain | 0.6614 | Inherited |
| MFS general substrate transporter | 0.6887 | Inherited |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0.6916 | Inherited |
| Glucocorticoid receptor-like (DNA-binding domain) | 0.6992 | Inherited |
| GST C-terminal domain-like | 0.7144 | Inherited |
| Frizzled cysteine-rich domain | 0.7242 | Inherited |
| 4Fe-4S ferredoxins | 0.7242 | Inherited |
| S15/NS1 RNA-binding domain | 0.7242 | Inherited |
| Ribonuclease H-like | 0.7521 | Inherited |
| PAZ domain | 0.7672 | Inherited |
| MIT domain | 0.7897 | Inherited |
| ADC-like | 0.7897 | Inherited |
| alpha/beta-Hydrolases | 0.8202 | Inherited |
| Fibronectin type III | 0.8286 | Inherited |
| Clavaminate synthase-like | 0.8622 | Inherited |
| EF-hand | 0.8653 | Inherited |
| Leucine zipper domain | 0.8753 | Inherited |
| GTPase activation domain, GAP | 0.8836 | Inherited |
| UBA-like | 0.8861 | Inherited |
| DNA/RNA polymerases | 0.9493 | Inherited |
| p53-like transcription factors | 0.9541 | Inherited |
| Ribonuclease PH domain 2-like | 0.9646 | Inherited |
| Thioredoxin-like | 0.9741 | Inherited |
| Immunoglobulin | 0.9747 | Inherited |
| Nuclear receptor ligand-binding domain | 0.9791 | Inherited |
| Saposin | 1 | Inherited |
| CoA-dependent acyltransferases | 1 | Inherited |
| beta-beta-alpha zinc fingers | 1 | Inherited |
| Family A G protein-coupled receptor-like | 1 | Inherited |
| Eukaryotic type KH-domain (KH-domain type I) | 1 | Inherited |
| Bet v1-like | 1 | Inherited |
| B-box zinc-binding domain | 1 | Inherited |
| F-box domain | 1 | Inherited |
| Cyclophilin-like | 1 | Inherited |
| Ligand-binding domain in the NO signalling and Golgi transport | 1 | Inherited |
| RING/U-box | 1 | Inherited |
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Family(show details)
Family domains annotated to this WP term (Not in SDWP)
Highlighted in gray are those with FDR_all>0.001
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| PLC-like (P variant) | 0 | DIRECT |
| Group II chaperonin (CCT, TRIC), intermediate domain | 0 | DIRECT |
| Biotin dependent carboxylase carboxyltransferase domain | 0 | DIRECT |
| Class I aldolase | 0 | DIRECT |
| Double-stranded RNA-binding domain (dsRBD) | 0 | DIRECT |
| Cullin repeat | 0 | DIRECT |
| IF2B-like | 0 | DIRECT |
| Fibrinogen C-terminal domain-like | 0 | DIRECT |
| Cytoplasmic domain of inward rectifier potassium channel | 0 | DIRECT |
| Sir2 family of transcriptional regulators | 0 | DIRECT |
| PEP carboxykinase N-terminal domain | 0 | DIRECT |
| Chitinase insertion domain | 0 | DIRECT |
| Serum paraoxonase/arylesterase 1, PON1 | 0 | DIRECT |
| Ubiquitin carboxyl-terminal hydrolase UCH-L | 0 | DIRECT |
| Helical domain of Sec23/24 | 0 | DIRECT |
| Type II chitinase | 0 | DIRECT |
| alpha-catenin/vinculin | 0 | DIRECT |
| LysM domain | 0 | DIRECT |
| PEP carboxykinase C-terminal domain | 0 | DIRECT |
| Thyroglobulin type-1 domain | 0 | DIRECT |
| Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains | 0 | DIRECT |
| Succinyl-CoA synthetase domains | 0 | DIRECT |
| CO dehydrogenase flavoprotein N-terminal domain-like | 0 | DIRECT |
| BEACH domain | 0 | DIRECT |
| RNA-polymerase beta-prime | 0 | DIRECT |
| Sec1/munc18-like (SM) proteins | 0 | DIRECT |
| Ribosomal protein S10 | 0 | DIRECT |
| 5' to 3' exonuclease catalytic domain | 0 | DIRECT |
| Peptidylglycine alpha-hydroxylating monooxygenase, PHM | 0 | DIRECT |
| Aminoacid dehydrogenase-like, C-terminal domain | 0 | DIRECT |
| UBA domain | 0 | DIRECT |
| Mitochondrial carrier | 0 | DIRECT |
| Hexokinase | 0 | DIRECT |
| Brix domain | 0 | DIRECT |
| Proton glutamate symport protein | 0 | DIRECT |
| Rap/Ran-GAP | 0 | DIRECT |
| Ribosomal protein L18 and S11 | 0 | DIRECT |
| Histone deacetylase, HDAC | 0 | DIRECT |
| Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta | 0 | DIRECT |
| Subtilases | 0 | DIRECT |
| Regulator of chromosome condensation RCC1 | 0 | DIRECT |
| 14-3-3 protein | 0 | DIRECT |
| Molybdenum cofactor-binding domain | 0 | DIRECT |
| acyl-CoA oxidase N-terminal domains | 0 | DIRECT |
| Blood coagulation inhibitor (disintegrin) | 0 | DIRECT |
| MFPT repeat | 0 | DIRECT |
| Hormone receptor domain | 0 | DIRECT |
| Carboxypeptidase regulatory domain | 0 | DIRECT |
| Hedgehog C-terminal (Hog) autoprocessing domain | 0 | DIRECT |
| CO dehydrogenase molybdoprotein N-domain-like | 0 | DIRECT |
| Nop domain | 0 | DIRECT |
| Inositol polyphosphate 5-phosphatase (IPP5) | 0 | DIRECT |
| Complement control module/SCR domain | 0 | DIRECT |
| Heat shock protein 90, HSP90, N-terminal domain | 0 | DIRECT |
| Sec63 N-terminal domain | 0 | DIRECT |
| Group II chaperonin (CCT, TRIC), apical domain | 0 | DIRECT |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Insulin-like | 0 | DIRECT |
| beta 1,4 galactosyltransferase (b4GalT1) | 0 | DIRECT |
| Pyk2-associated protein beta ARF-GAP domain | 0 | DIRECT |
| YbiA-like | 0 | DIRECT |
| Alcohol dehydrogenase-like, C-terminal domain | 0 | DIRECT |
| HD domain | 0 | DIRECT |
| DEP domain | 0 | DIRECT |
| Carbonic anhydrase | 0 | DIRECT |
| MOSC N-terminal domain-like | 0 | DIRECT |
| Methionine aminopeptidase, insert domain | 0 | DIRECT |
| NHL repeat | 0 | DIRECT |
| POU-specific domain | 0 | DIRECT |
| NTF2-like | 0 | DIRECT |
| Skp1 dimerisation domain-like | 0 | DIRECT |
| Acylamino-acid-releasing enzyme, C-terminal donain | 0 | DIRECT |
| YihX-like | 0 | DIRECT |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | DIRECT |
| WWE domain | 0 | DIRECT |
| ALDH-like | 0 | DIRECT |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
| L-aminoacid/polyamine oxidase | 0 | DIRECT |
| Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain | 0 | DIRECT |
| Troponin I | 0 | DIRECT |
| Purine and uridine phosphorylases | 0 | DIRECT |
| Pleckstrin-homology domain (PH domain) | 0 | DIRECT |
| UDP-glucose pyrophosphorylase | 0 | DIRECT |
| Glycosyl transferases group 1 | 0 | DIRECT |
| Phosphate binding protein-like | 0 | DIRECT |
| Proteasome subunits | 0 | DIRECT |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
| PDEase | 0 | DIRECT |
| Erythroid transcription factor GATA-1 | 0 | DIRECT |
| Spectrin repeat | 0 | DIRECT |
| SWIB/MDM2 domain | 0 | DIRECT |
| Phoshoinositide 3-kinase (PI3K) helical domain | 0 | DIRECT |
| Glycerol kinase | 0 | DIRECT |
| Thiolase-related | 0 | DIRECT |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | DIRECT |
| DPP6 catalytic domain-like | 0 | DIRECT |
| WGR domain | 0 | DIRECT |
| Translational machinery components | 0 | DIRECT |
| Ras-binding domain, RBD | 0 | DIRECT |
| LEM domain | 0 | DIRECT |
| GAS2 domain | 0 | DIRECT |
| MIR domain | 0 | DIRECT |
| Nucleoside diphosphate kinase, NDK | 0 | DIRECT |
| Cation efflux protein cytoplasmic domain-like | 0 | DIRECT |
| Dimeric isocitrate & isopropylmalate dehydrogenases | 0 | DIRECT |
| Fatty acid binding protein-like | 0 | DIRECT |
| D-aminoacid oxidase, N-terminal domain | 0 | DIRECT |
| Reductases | 0 | DIRECT |
| GYF domain | 0 | DIRECT |
| Polo-box duplicated region | 0 | DIRECT |
| MIF4G domain-like | 0 | DIRECT |
| Bactericidal permeability-increasing protein, BPI | 0 | DIRECT |
| Group II chaperonin (CCT, TRIC), ATPase domain | 0 | DIRECT |
| alpha-mannosidase | 0 | DIRECT |
| SCF ubiquitin ligase complex WHB domain | 0 | DIRECT |
| Armadillo repeat | 0 | DIRECT |
| Clathrin adaptor core protein | 0 | DIRECT |
| Proprotein convertase P-domain | 0 | DIRECT |
| Adenosine/AMP deaminase | 0 | DIRECT |
| Acireductone dioxygenase | 0 | DIRECT |
| HCDH C-domain-like | 0 | DIRECT |
| DNA replication initiator (cdc21/cdc54) N-terminal domain | 0 | DIRECT |
| First domain of FERM | 0 | DIRECT |
| Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | DIRECT |
| acyl-CoA oxidase C-terminal domains | 0 | DIRECT |
| Poly(ADP-ribose) polymerase, C-terminal domain | 0 | DIRECT |
| YicI catalytic domain-like | 0 | DIRECT |
| Medium chain acyl-CoA dehydrogenase-like, C-terminal domain | 0 | DIRECT |
| Cell cycle control phosphatase, catalytic domain | 0 | DIRECT |
| FF domain | 0 | DIRECT |
| Transducin (alpha subunit), insertion domain | 0 | DIRECT |
| Cyclin | 0 | DIRECT |
| cAMP-binding domain | 0 | DIRECT |
| Third domain of FERM | 0 | DIRECT |
| PurM C-terminal domain-like | 0 | DIRECT |
| Lamin A/C globular tail domain | 0 | DIRECT |
| Epoxide hydrolase | 0 | DIRECT |
| Anticodon-binding domain of Class II aaRS | 0 | DIRECT |
| Domain of poly(ADP-ribose) polymerase | 0 | DIRECT |
| Alcohol dehydrogenase-like, N-terminal domain | 0 | DIRECT |
| Acyl-carrier protein (ACP) | 0 | DIRECT |
| Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | DIRECT |
| Biotinyl/lipoyl-carrier proteins and domains | 0 | DIRECT |
| CRAL/TRIO N-terminal domain | 0 | DIRECT |
| BC C-terminal domain-like | 0 | DIRECT |
| Zn-finger domain of Sec23/24 | 0 | DIRECT |
| Lipovitellin-phosvitin complex, superhelical domain | 0 | DIRECT |
| Ubiquitin activating enzymes (UBA) | 0 | DIRECT |
| PABC (PABP) domain | 0 | DIRECT |
| Phosphoglucomutase, first 3 domains | 0 | DIRECT |
| Quinoprotein alcohol dehydrogenase-like | 0 | DIRECT |
| Annexin | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
| DNA gyrase/MutL, N-terminal domain | 0 | DIRECT |
| Hydantoinase (dihydropyrimidinase), catalytic domain | 0 | DIRECT |
| PDI-like | 0 | DIRECT |
| DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
| Small-conductance potassium channel | 0 | DIRECT |
| Calcium ATPase, transmembrane domain M | 0 | DIRECT |
| Gamma-glutamyltranspeptidase-like | 0 | DIRECT |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | DIRECT |
| VHS domain | 0 | DIRECT |
| ATP-dependent protease Lon (La), catalytic domain | 0 | DIRECT |
| COMT-like | 0 | DIRECT |
| Doublecortin (DC) | 0 | DIRECT |
| Adenain-like | 0 | DIRECT |
| BAR domain | 0 | DIRECT |
| SMAD domain | 0 | DIRECT |
| AN1-like Zinc finger | 0 | DIRECT |
| Profilin (actin-binding protein) | 0 | DIRECT |
| Reprolysin-like | 0 | DIRECT |
| Cadherin | 0 | DIRECT |
| Ribokinase-like | 0 | DIRECT |
| Glycerophosphoryl diester phosphodiesterase | 0 | DIRECT |
| PUA domain | 0 | DIRECT |
| Poly(A) polymerase, PAP, N-terminal domain | 0 | DIRECT |
| DPP6 N-terminal domain-like | 0 | DIRECT |
| alpha-mannosidase, domain 2 | 0 | DIRECT |
| SAM (sterile alpha motif) domain | 0 | DIRECT |
| Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain | 0 | DIRECT |
| Pancreatic carboxypeptidase, activation domain | 0 | DIRECT |
| Tubulin, GTPase domain | 0 | DIRECT |
| BC ATP-binding domain-like | 0 | DIRECT |
| PaaI/YdiI-like | 0 | DIRECT |
| Inositol polyphosphate kinase (IPK) | 0 | DIRECT |
| Ribonucleotide reductase-like | 0 | DIRECT |
| Protein prenyltransferases | 0 | DIRECT |
| Heme-dependent catalases | 0 | DIRECT |
| Class II glutamine amidotransferases | 0 | DIRECT |
| Translation initiation factor eIF4e | 0 | DIRECT |
| Laminin G-like module | 0 | DIRECT |
| Band 7/SPFH domain | 0 | DIRECT |
| HSP20 | 0 | DIRECT |
| Ngr ectodomain-like | 0 | DIRECT |
| a tRNA synthase domain | 0 | DIRECT |
| HEAT repeat | 0 | DIRECT |
| SMAD MH1 domain | 0 | DIRECT |
| LacY-like proton/sugar symporter | 0 | DIRECT |
| FAD-dependent thiol oxidase | 0 | DIRECT |
| Glycogenin | 0 | DIRECT |
| Arylsulfatase | 0 | DIRECT |
| RecA protein-like (ATPase-domain) | 0 | DIRECT |
| HAT/Suf repeat | 0 | DIRECT |
| beta-Lactamase/D-ala carboxypeptidase | 0 | DIRECT |
| Tim10/DDP | 0 | DIRECT |
| La domain | 0 | DIRECT |
| DEATH domain, DD | 0 | DIRECT |
| Inositol monophosphatase/fructose-1,6-bisphosphatase-like | 0 | DIRECT |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | DIRECT |
| CUT domain | 0 | DIRECT |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
| Poly(A) polymerase, PAP, C-terminal domain | 0 | DIRECT |
| Paired domain | 0 | DIRECT |
| Branched-chain alpha-keto acid dehydrogenase PP module | 0 | DIRECT |
| D-aminoacid oxidase-like | 0 | DIRECT |
| Ribosomal protein L1 | 0 | DIRECT |
| Tubulin, C-terminal domain | 0 | DIRECT |
| Chaperone J-domain | 0 | DIRECT |
| DNA repair protein MutS, domain III | 0 | DIRECT |
| Second domain of FERM | 0 | DIRECT |
| HSP90 C-terminal domain | 0 | DIRECT |
| Ran binding protein zinc finger-like | 0 | DIRECT |
| Anticodon-binding domain | 0 | DIRECT |
| Phosphatidylethanolamine binding protein | 0 | DIRECT |
| NOL1/NOP2/sun | 0 | DIRECT |
| Lactate & malate dehydrogenases, C-terminal domain | 0 | DIRECT |
| Pancreatic carboxypeptidases | 0 | DIRECT |
| CoA-binding domain | 0 | DIRECT |
| t-snare proteins | 0 | DIRECT |
| L30e/L7ae ribosomal proteins | 0 | DIRECT |
| alpha-mannosidase, C-terminal domain | 0 | DIRECT |
| AAT-like | 0 | DIRECT |
| Aquaporin-like | 0 | DIRECT |
| RNA-polymerase beta | 0 | DIRECT |
| XPF/Rad1/Mus81 nuclease | 0 | DIRECT |
| Cullin homology domain | 0 | DIRECT |
| F1F0 ATP synthase subunit C | 0 | DIRECT |
| PurM N-terminal domain-like | 0 | DIRECT |
| Matrix metalloproteases, catalytic domain | 0 | DIRECT |
| YWTD domain | 0 | DIRECT |
| PhzC/PhzF-like | 0 | DIRECT |
| Surp module (SWAP domain) | 0 | DIRECT |
| Filamin repeat (rod domain) | 0 | DIRECT |
| Mammalian PLC | 0 | DIRECT |
| S-adenosylmethionine synthetase | 0 | DIRECT |
| Sec63 C-terminal domain-like | 0 | DIRECT |
| Regulator of G-protein signaling, RGS | 0 | DIRECT |
| Actin/HSP70 | 0 | DIRECT |
| Hydantoinase (dihydropyrimidinase) | 0 | DIRECT |
| Ferredoxin reductase FAD-binding domain-like | 0 | DIRECT |
| 28-residue LRR | 0 | DIRECT |
| Formate/glycerate dehydrogenases, NAD-domain | 0 | DIRECT |
| Cu,Zn superoxide dismutase-like | 0 | DIRECT |
| Phoshoinositide 3-kinase (PI3K), catalytic domain | 0 | DIRECT |
| Amylase, catalytic domain | 0 | DIRECT |
| Myeloperoxidase-like | 0 | DIRECT |
| Arginine methyltransferase | 0 | DIRECT |
| Poly(A) polymerase, PAP, middle domain | 0 | DIRECT |
| Chromo domain | 0 | DIRECT |
| Oxysterol-binding protein | 0 | DIRECT |
| CAT-like | 0 | DIRECT |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Sterol carrier protein, SCP | 0 | DIRECT |
| ets domain | 0 | DIRECT |
| Internalin LRR domain | 0 | DIRECT |
| Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | DIRECT |
| Calpain large subunit, catalytic domain (domain II) | 0 | DIRECT |
| Hypothetical protein c14orf129, hspc210 | 0 | DIRECT |
| GAPDH-like | 0 | DIRECT |
| Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain | 0 | DIRECT |
| Trunk domain of Sec23/24 | 0 | DIRECT |
| Integrin domains | 0 | DIRECT |
| Choline kinase | 0 | DIRECT |
| 1,3-glucuronyltransferase | 0 | DIRECT |
| Cdc48 domain 2-like | 0 | DIRECT |
| Smc hinge domain | 0 | DIRECT |
| Intermediate filament protein, coiled coil region | 0 | DIRECT |
| Pepsin inhibitor-3 | 0 | DIRECT |
| Cofilin-like | 0 | DIRECT |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
| ValRS/IleRS/LeuRS editing domain | 0 | DIRECT |
| FtsH protease domain-like | 0 | DIRECT |
| RNA editing terminal uridyl transferase 2, RET2, domain 2 | 0 | DIRECT |
| RhoGDI-like | 0 | DIRECT |
| Branched-chain alpha-keto acid dehydrogenase Pyr module | 0 | DIRECT |
| Phosphoribosyltransferases (PRTases) | 0 | DIRECT |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | DIRECT |
| BC N-terminal domain-like | 0 | DIRECT |
| Sec7 domain | 0 | DIRECT |
| Lesion bypass DNA polymerase (Y-family), catalytic domain | 0 | DIRECT |
| Glutaminase | 0 | DIRECT |
| Class I glutamine amidotransferases (GAT) | 0 | DIRECT |
| Acyl-CoA thioesterase | 0 | DIRECT |
| FHA domain | 0 | DIRECT |
| p120GAP domain-like | 0 | DIRECT |
| Tetraspanin | 0 | DIRECT |
| LDH N-terminal domain-like | 0 | DIRECT |
| MutT-like | 0 | DIRECT |
| DNA gyrase/MutL, second domain | 0 | DIRECT |
| Hsp90 middle domain | 0 | DIRECT |
| Phosphotyrosine-binding domain (PTB) | 0 | DIRECT |
| Glycolipid transfer protein, GLTP | 0 | DIRECT |
| Elafin-like | 0 | DIRECT |
| beta-sandwich domain of Sec23/24 | 0 | DIRECT |
| Arfaptin, Rac-binding fragment | 0 | DIRECT |
| Citrate synthase | 0 | DIRECT |
| Linker histone H1/H5 | 0 | DIRECT |
| alpha-Amylases, C-terminal beta-sheet domain | 0 | DIRECT |
| Single strand DNA-binding domain, SSB | 0 | DIRECT |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
| U-box | 0 | DIRECT |
| Bacterial exopeptidase dimerisation domain | 0 | DIRECT |
| Clathrin coat assembly domain | 0 | DIRECT |
| 2Fe-2S ferredoxin domains from multidomain proteins | 0 | DIRECT |
| Nucleosome core histones | 0 | DIRECT |
| Clc chloride channel | 0 | DIRECT |
| Myotubularin-like phosphatases | 0 | DIRECT |
| AMPK-beta glycogen binding domain-like | 0 | DIRECT |
| CO dehydrogenase ISP C-domain like | 0 | DIRECT |
| Type II DNA topoisomerase | 0 | DIRECT |
| ARID domain | 0 | DIRECT |
| SWIRM domain | 0 | DIRECT |
| HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
| SAND domain | 0 | DIRECT |
| Transducin (heterotrimeric G protein), gamma chain | 0 | DIRECT |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
| Tandem AAA-ATPase domain | 0.0003226 | DIRECT |
| Protein kinases, catalytic subunit | 0.01091 | INHERITED FROM: egg laying response to food variant || second messenger mediated signaling variant || conflicting sensory integration variant || protein subcellular localization variant || chemical response variant || protein phosphorylation variant || copper response variant || kinase activity reduced || aldicarb response variant || alkaline pH chemotaxis variant || drug induced gene expression variant || oxygen response variant || metal response variant || octanol chemotaxis defective || protein phosphorylation reduced || anoxia resistant || mechanosensation variant || lipid synthesis increased || protein modification variant || positive chemotaxis variant || protein expression variant || pathogen induced gene expression variant |
| G proteins | 0.03566 | INHERITED FROM: bacterially unswollen || protein subcellular localization variant || organism metabolism processing variant || protein phosphorylation variant || chemosensory response variant || aldicarb response variant || drug induced gene expression variant || chemotaxis variant || fat content variant || organism environmental stimulus response variant || osmotic integrity variant || carbon dioxide avoidance variant || carbon dioxide response variant |
| Homeodomain | 0.03756 | INHERITED FROM: level of transgene expression variant || sexually dimorphic physiology variant || organism metabolism processing variant || ectopic expression transgene || carbon dioxide avoidance variant || carbon dioxide response variant |
| WD40-repeat | 0.04776 | INHERITED FROM: antimicrobial gene expression variant || dauer defective || osmotic avoidance variant || late larval arrest || organism metabolism processing variant || protein aggregation induced behavior variant |
| PDZ domain | 0.06423 | INHERITED FROM: egg laying serotonin variant || drug response variant || aldicarb response variant || protein expression variant |
| MSP-like | 0.06681 | INHERITED FROM: developmental growth variant || dauer lifespan variant || lipid metabolism variant || larval arrest || dauer lifespan extended || larval growth variant || slow growth || dauer metabolism variant || fat content variant |
| SH2 domain | 0.06969 | INHERITED FROM: protein expression reduced || level of protein expression variant || protein expression variant |
| L-arabinose binding protein-like | 0.07068 | INHERITED FROM: anion positive chemotaxis variant || bromide chemotaxis variant || iodide chemotaxis defective || iodide chemotaxis variant || chemosensory response variant || alkaline pH chemotaxis variant || bromide chemotaxis defective || lithium chemotaxis defective || chemotaxis variant || cation positive chemotaxis variant || organism environmental stimulus response variant || magnesium chemotaxis defective || anion positive chemotaxis defective || cation positive chemotaxis defective |
| Acetyl-CoA synthetase-like | 0.08526 | INHERITED FROM: lipid metabolism variant |
| Calponin-homology domain, CH-domain | 0.08526 | INHERITED FROM: protein degradation variant |
| Canonical RBD | 0.09247 | INHERITED FROM: no induction of antimicrobial peptide expression after infection || antimicrobial gene expression variant || sick || late larval arrest || organism metabolism processing variant || mRNA export variant || RNA processing variant || starvation induced apoptosis variant || RNA expression variant || innate immune response variant |
| CCCH zinc finger | 0.1029 | INHERITED FROM: transgene expression variant || mRNA expression ectopic || ectopic expression transgene || gene expression variant |
| ABC transporter ATPase domain-like | 0.1052 | INHERITED FROM: RNAi response variant || metal response variant || colchicine hypersensitive || cadmium response variant |
| Tetratricopeptide repeat (TPR) | 0.1403 | INHERITED FROM: organism metabolism processing variant |
| Cold shock DNA-binding domain-like | 0.1501 | INHERITED FROM: nonsense mRNA accumulation || sick || mRNA surveillance defective |
| Adenylyl and guanylyl cyclase catalytic domain | 0.1628 | INHERITED FROM: bromide chemotaxis variant || second messenger mediated signaling variant || iodide chemotaxis defective || iodide chemotaxis variant || osmotic avoidance variant || AWC odorant chemotaxis defective || chemosensory response variant || AWC odorant chemotaxis variant || alkaline pH chemotaxis variant || bromide chemotaxis defective || diacetyl chemotaxis variant || lithium chemotaxis defective || chemotaxis variant || cation positive chemotaxis variant || organism environmental stimulus response variant || magnesium chemotaxis defective || anion positive chemotaxis defective || positive chemotaxis variant || carbon dioxide response variant || cation positive chemotaxis defective |
| HLH, helix-loop-helix DNA-binding domain | 0.1628 | INHERITED FROM: hypoxia response variant || lysine chemotaxis defective || ectopic expression transgene || gene expression level reduced || RNA expression variant || fungal resistance increased || pathogen resistance increased |
| Calcium ATPase, transduction domain A | 0.1981 | INHERITED FROM: drug hypersensitive || nicotine hypersensitive || organism environmental stimulus response variant |
| SH3-domain | 0.2285 | INHERITED FROM: protein expression reduced || aldicarb response variant || protein expression variant |
| Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain | 0.2377 | INHERITED FROM: transgene expression variant || hypoxia resistant || organism metabolism processing variant || hypoxia response variant || oxygen response variant || organism environmental stimulus response variant || gene expression variant |
| DBL homology domain (DH-domain) | 0.2377 | INHERITED FROM: bacterially unswollen || aldicarb response variant || organism pathogen response variant || organism environmental stimulus response variant || pathogen resistance increased |
| Pepsin-like | 0.2377 | INHERITED FROM: pattern of transgene expression variant || transgene expression variant || protein aggregation variant || organism metabolism processing variant || protein protein interaction variant || protein interaction variant || transgene subcellular localization variant || hypoosmotic shock hypersensitive || osmotic integrity variant || gene expression variant |
| Histone lysine methyltransferases | 0.2377 | INHERITED FROM: ectopic expression antibody || histone methylation variant || mRNA expression variant || somatic transgene silencing variant || RNAi response variant || life span variant || protein methylation variant || maintenance of gene silencing variant || protein modification variant || protein expression variant |
| Extended PAW domain | 0.2377 | INHERITED FROM: pattern of transgene expression variant || protein aggregation variant || protein protein interaction variant || protein interaction variant || transgene subcellular localization variant |
| Elongation factors | 0.2377 | INHERITED FROM: mRNA levels increased || protein aggregation variant || mRNA levels reduced || proteasome core activity variant || protein protein interaction variant || protein phosphorylation variant || protein phosphorylation increased || protein modification variant |
| Class I aminoacyl-tRNA synthetases (RS), catalytic domain | 0.2377 | INHERITED FROM: antimicrobial gene expression variant || hypoxia resistant || paraquat resistant || organism metabolism processing variant || paraquat response variant || hypoxia response variant || oxygen response variant || transgene expression increased || organism environmental stimulus response variant || innate immune response variant || gene expression variant |
| Acetylcholinesterase-like | 0.2564 | INHERITED FROM: enzyme activity variant || acetylcholinesterase activity variant || enzyme activity reduced || acetylcholinesterase reduced |
| Dual specificity phosphatase-like | 0.2603 | INHERITED FROM: level of transgene expression variant || organism metabolism processing variant || transgene expression reduced || gene expression variant |
| HMG-box | 0.2603 | INHERITED FROM: maintenance of gene silencing variant |
| EGF-type module | 0.2846 | INHERITED FROM: mechanosensation variant |
| Metal cation-transporting ATPase, ATP-binding domain N | 0.2846 | INHERITED FROM: drug hypersensitive || nicotine hypersensitive || organism environmental stimulus response variant |
| Ankyrin repeat | 0.2977 | INHERITED FROM: octanol chemotaxis variant || organism heat response variant || odorant negative chemotaxis defective || octanol chemotaxis defective |
| Extended AAA-ATPase domain | 0.3045 | INHERITED FROM: sick || protein expression increased || spontaneous mutation rate increased |
| Multidrug efflux transporter AcrB transmembrane domain | 0.3062 | INHERITED FROM: odorant chemosensory response variant || odorant positive chemotaxis defective || egg integrity defective early emb || positive chemotaxis defective || embryo osmotic integrity defective early emb || chemotaxis variant |
| Bromodomain | 0.3111 | INHERITED FROM: drug adaptation variant || sick || acute functional tolerance to alcohol defective || organism stress response variant || organism UV response variant || anesthetic response variant || ethanol resistant || anesthetic resistant || organism UV hypersensitive |
| FYVE, a phosphatidylinositol-3-phosphate binding domain | 0.3111 | INHERITED FROM: acetylcholinesterase inhibitor resistant || aldicarb resistant |
| 6-phosphogluconate dehydrogenase-like, N-terminal domain | 0.3111 | INHERITED FROM: lipid metabolism variant || fat content variant |
| Cytochrome P450 | 0.3254 | INHERITED FROM: metal response variant || cadmium response variant |
| FAD/NAD-linked reductases, N-terminal and central domains | 0.3407 | INHERITED FROM: paraquat response variant || organism oxidative stress response variant || pesticide response variant |
| Crotonase-like | 0.373 | INHERITED FROM: lipid metabolism variant || fat content variant |
| Sm motif of small nuclear ribonucleoproteins, SNRNP | 0.373 | INHERITED FROM: pattern of transgene expression variant || sick || protein subcellular localization variant || protein aggregation variant || protein protein interaction variant || life span variant || pattern protein expression variant |
| Meta-cation ATPase, catalytic domain P | 0.373 | INHERITED FROM: nicotine hypersensitive || organism environmental stimulus response variant |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.402 | INHERITED FROM: slowing response on food variant || sodium chloride chemotaxis variant || DMPP response variant || chemical response variant || drug response variant || cholinergic agonist resistant || ivermectin response variant || hypoosmotic shock hypersensitive || aqueous chemosensory response variant || mechanosensation variant || organism environmental stimulus response variant || selenium response variant || antihelmintic response variant || nicotine resistant || ivermectin resistant |
| Pumilio repeat | 0.4439 | INHERITED FROM: protein expression ectopic |
| GABA-aminotransferase-like | 0.4439 | INHERITED FROM: fat content reduced |
| FKBP immunophilin/proline isomerase | 0.458 | INHERITED FROM: pattern of transgene expression variant || protein aggregation variant || protein protein interaction variant || protein interaction variant || transgene subcellular localization variant |
| ABC transporter transmembrane region | 0.4662 | INHERITED FROM: RNAi response variant || metal response variant || colchicine hypersensitive || organism environmental stimulus response variant || cadmium response variant |
| Protein kinase cysteine-rich domain (cys2, phorbol-binding domain) | 0.4767 | INHERITED FROM: antimicrobial gene expression variant || protein subcellular localization variant || odorant chemosensory response variant || aldicarb response variant || drug induced gene expression variant || odorant positive chemotaxis variant || nose touch variant || organism pathogen response variant || drug resistant |
| Cation efflux protein transmembrane domain-like | 0.4831 | INHERITED FROM: manganese toxicity resistant || manganese response variant || metal response variant || cadmium response variant || cadmium hypersensitive |
| Glutathione S-transferase (GST), N-terminal domain | 0.5087 | INHERITED FROM: enzyme activity variant || organism stress response variant || paraquat response variant || organism electrophilic stress hypersensitive || enzyme activity reduced || organism heat hypersensitive || organism environmental stimulus response variant || cadmium response variant || cadmium hypersensitive |
| Hect, E3 ligase catalytic domain | 0.5274 | INHERITED FROM: pattern of transgene expression variant || transgene expression variant || protein aggregation variant || organism metabolism processing variant || protein protein interaction variant || protein interaction variant || transgene subcellular localization variant || protein aggregation induced behavior variant || gene expression variant |
| Myosin rod fragments | 0.5274 | INHERITED FROM: drug resistant |
| Pyridoxal-dependent decarboxylase | 0.5274 | INHERITED FROM: egg laying response to drug variant || drug response variant || carbon dioxide avoidance variant || carbon dioxide response variant |
| Nicotinic receptor ligand binding domain-like | 0.5362 | INHERITED FROM: slowing response on food variant || sodium chloride chemotaxis variant || DMPP response variant || chemical response variant || drug response variant || cholinergic agonist resistant || ivermectin response variant || hypoosmotic shock hypersensitive || aqueous chemosensory response variant || mechanosensation variant || organism environmental stimulus response variant || selenium response variant || antihelmintic response variant || nicotine resistant || ivermectin resistant |
| I set domains | 0.5666 | INHERITED FROM: metabolic pathway variant || aldicarb response variant || growth rate variant || protein degradation variant || organism environmental stimulus response variant || aldicarb resistant |
| Gastric lipase | 0.5726 | INHERITED FROM: lipid metabolism variant || fat content variant |
| Myb/SANT domain | 0.5726 | INHERITED FROM: growth rate variant |
| Calpain large subunit, middle domain (domain III) | 0.5726 | INHERITED FROM: metabolic pathway variant || protein metabolism variant || protein degradation variant |
| Papain-like | 0.5854 | INHERITED FROM: pattern of transgene expression variant || transgene expression variant || protein aggregation variant || organism metabolism processing variant || protein protein interaction variant || protein interaction variant || hypoosmotic shock hypersensitive || osmotic integrity variant || gene expression variant |
| WW domain | 0.5987 | INHERITED FROM: maintenance of gene silencing variant |
| Class I alpha-1;2-mannosidase, catalytic domain | 0.6242 | INHERITED FROM: protein aggregation variant || protein protein interaction variant || extended life span |
| UBC-related | 0.6394 | INHERITED FROM: pattern of transgene expression variant || transgene expression variant || protein aggregation variant || late larval arrest || organism metabolism processing variant || protein protein interaction variant || protein interaction variant || transgene subcellular localization variant || gene expression variant |
| Synaptotagmin-like (S variant) | 0.6669 | INHERITED FROM: protein subcellular localization variant || acetylcholinesterase inhibitor response variant || drug response variant || acetylcholinesterase inhibitor resistant || pattern protein expression variant || drug resistant |
| Osmotin, thaumatin-like protein | 0.6782 | INHERITED FROM: metal response variant || cadmium response variant || cadmium hypersensitive |
| Ubiquitin carboxyl-terminal hydrolase, UCH | 0.6925 | INHERITED FROM: pattern of transgene expression variant || transgene expression variant || protein aggregation variant || organism metabolism processing variant || protein protein interaction variant || protein interaction variant || gene expression variant |
| BTB/POZ domain | 0.7037 | INHERITED FROM: L1 arrest || chemical response variant || chemical hypersensitive || early larval arrest || protein aggregation induced behavior variant || resistant to protein aggregation induced paralysis |
| EF-hand modules in multidomain proteins | 0.7376 | INHERITED FROM: protein expression variant |
| Frizzled cysteine-rich domain | 0.7376 | INHERITED FROM: transgene expression reduced || antibody staining variant |
| Transforming growth factor (TGF)-beta | 0.7376 | INHERITED FROM: level of transgene expression variant || levamisole response variant || nicotine response variant || drug response variant || transgene expression reduced |
| PHD domain | 0.7668 | INHERITED FROM: organism UV response variant || RNAi response variant || ectopic expression transgene || protein methylation variant || organism environmental stimulus response variant || protein modification variant || RNAi resistant || organism UV hypersensitive |
| Cdc48 N-terminal domain-like | 0.8021 | INHERITED FROM: metabolic pathway variant || protein aggregation variant || protein protein interaction variant || protein interaction variant || protein metabolism variant |
| H-NOX domain | 0.8021 | INHERITED FROM: carbon dioxide avoidance variant || carbon dioxide response variant |
| Bacterial lipase | 0.8021 | INHERITED FROM: lipid metabolism variant || fat content variant |
| MIT domain | 0.8021 | INHERITED FROM: protein aggregation variant || protein protein interaction variant || protein interaction variant |
| Ubiquitin-related | 0.8031 | INHERITED FROM: transgene expression variant || protein aggregation variant || organism metabolism processing variant || protein protein interaction variant || protein interaction variant || hypersensitive to protein aggregation induced paralysis |
| Voltage-gated potassium channels | 0.8104 | INHERITED FROM: adrenergic receptor antagonist response variant || AWA odorant chemotaxis variant || growth rate variant || serotonin response variant || protein metabolism variant || protein degradation variant |
| FAD-linked reductases, N-terminal domain | 0.8433 | INHERITED FROM: shortened life span |
| PAZ domain | 0.8679 | INHERITED FROM: mRNA levels increased || 21U RNA expression variant || RNAi response variant || siRNA expression variant || RNA expression variant || RNAi enhanced || maintenance of gene silencing variant |
| LIM domain | 0.8802 | INHERITED FROM: protein expression reduced || level of protein expression variant || protein degradation variant |
| Fibronectin type III | 0.8926 | INHERITED FROM: protein degradation variant |
| Glutathione S-transferase (GST), C-terminal domain | 0.9105 | INHERITED FROM: enzyme activity variant || organism stress response variant || organism electrophilic stress hypersensitive || enzyme activity reduced || cadmium response variant || cadmium hypersensitive |
| Leucine zipper domain | 0.919 | INHERITED FROM: level of transgene expression variant || mRNA levels reduced || pore forming toxin response variant || transgene expression reduced || pathogen susceptibility increased |
| DnaQ-like 3'-5' exonuclease | 0.9274 | INHERITED FROM: RNAi response variant |
| Nuclear receptor ligand-binding domain | 0.942 | INHERITED FROM: fat content increased || SDS sensitive dauer || lipid metabolism variant || gene expression level reduced || transgene expression reduced || gene expression level high || dauer resistance to harsh conditions variant |
| Calmodulin-like | 0.9424 | INHERITED FROM: protein aggregation variant || protein protein interaction variant || protein interaction variant || transgene subcellular localization variant |
| Ribonuclease PH domain 1-like | 0.9772 | INHERITED FROM: early larval arrest |
| Ribonuclease PH domain 2-like | 0.9772 | INHERITED FROM: early larval arrest |
| NagD-like | 0.9772 | INHERITED FROM: dauer formation variant || dauer constitutive |
| Glutathione peroxidase-like | 1 | INHERITED FROM: paraquat response variant || pesticide response variant |
| RING finger domain, C3HC4 | 1 | INHERITED FROM: pattern of transgene expression variant || protein aggregation variant || organism metabolism processing variant || protein protein interaction variant || protein interaction variant || transgene subcellular localization variant |
| B-box zinc-binding domain | 1 | INHERITED FROM: transgene expression variant || protein aggregation variant || protein protein interaction variant || protein interaction variant || transgene subcellular localization variant || gene expression variant |
| Cyclophilin (peptidylprolyl isomerase) | 1 | INHERITED FROM: pattern of transgene expression variant || transgene expression variant || protein aggregation variant || protein protein interaction variant || protein interaction variant || transgene subcellular localization variant |
| Choline/Carnitine O-acyltransferase | 1 | INHERITED FROM: lipid metabolism variant || fat content variant |
| Nuclear receptor | 1 | INHERITED FROM: fat content increased || SDS sensitive dauer || gene expression level reduced || transgene expression reduced || gene expression level high || dauer resistance to harsh conditions variant |
| F-box domain | 1 | INHERITED FROM: protein aggregation induced behavior variant || resistant to protein aggregation induced paralysis |
| Rhodopsin-like | 1 | INHERITED FROM: aqueous adaptation defective || drug withdrawal response variant || serotonin hypersensitive || serotonin induced pumping variant || egg laying response to drug variant || serotonin induced fat reduction variant || male tail curling serotonin variant || serotonin response variant || serotonin resistant || organism pathogen response variant || locomotion rate serotonin variant || biogenic amine receptor antagonist resistant |
| C-type lectin domain | 1 | INHERITED FROM: pathogen induced death increased |
| N-acetyl transferase, NAT | 1 | INHERITED FROM: ectopic expression transgene |
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| PLC-like (P variant) | 0 | Direct |
| Group II chaperonin (CCT, TRIC), intermediate domain | 0 | Direct |
| Biotin dependent carboxylase carboxyltransferase domain | 0 | Direct |
| Class I aldolase | 0 | Direct |
| Double-stranded RNA-binding domain (dsRBD) | 0 | Direct |
| Cullin repeat | 0 | Direct |
| IF2B-like | 0 | Direct |
| Fibrinogen C-terminal domain-like | 0 | Direct |
| Cytoplasmic domain of inward rectifier potassium channel | 0 | Direct |
| Sir2 family of transcriptional regulators | 0 | Direct |
| PEP carboxykinase N-terminal domain | 0 | Direct |
| Chitinase insertion domain | 0 | Direct |
| Serum paraoxonase/arylesterase 1, PON1 | 0 | Direct |
| Ubiquitin carboxyl-terminal hydrolase UCH-L | 0 | Direct |
| Helical domain of Sec23/24 | 0 | Direct |
| Type II chitinase | 0 | Direct |
| alpha-catenin/vinculin | 0 | Direct |
| LysM domain | 0 | Direct |
| PEP carboxykinase C-terminal domain | 0 | Direct |
| Thyroglobulin type-1 domain | 0 | Direct |
| Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains | 0 | Direct |
| Succinyl-CoA synthetase domains | 0 | Direct |
| CO dehydrogenase flavoprotein N-terminal domain-like | 0 | Direct |
| BEACH domain | 0 | Direct |
| RNA-polymerase beta-prime | 0 | Direct |
| Sec1/munc18-like (SM) proteins | 0 | Direct |
| Ribosomal protein S10 | 0 | Direct |
| 5' to 3' exonuclease catalytic domain | 0 | Direct |
| Peptidylglycine alpha-hydroxylating monooxygenase, PHM | 0 | Direct |
| Aminoacid dehydrogenase-like, C-terminal domain | 0 | Direct |
| UBA domain | 0 | Direct |
| Mitochondrial carrier | 0 | Direct |
| Hexokinase | 0 | Direct |
| Brix domain | 0 | Direct |
| Proton glutamate symport protein | 0 | Direct |
| Rap/Ran-GAP | 0 | Direct |
| Ribosomal protein L18 and S11 | 0 | Direct |
| Histone deacetylase, HDAC | 0 | Direct |
| Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta | 0 | Direct |
| Subtilases | 0 | Direct |
| Regulator of chromosome condensation RCC1 | 0 | Direct |
| 14-3-3 protein | 0 | Direct |
| Molybdenum cofactor-binding domain | 0 | Direct |
| acyl-CoA oxidase N-terminal domains | 0 | Direct |
| Blood coagulation inhibitor (disintegrin) | 0 | Direct |
| MFPT repeat | 0 | Direct |
| Hormone receptor domain | 0 | Direct |
| Carboxypeptidase regulatory domain | 0 | Direct |
| Hedgehog C-terminal (Hog) autoprocessing domain | 0 | Direct |
| CO dehydrogenase molybdoprotein N-domain-like | 0 | Direct |
| Nop domain | 0 | Direct |
| Inositol polyphosphate 5-phosphatase (IPP5) | 0 | Direct |
| Complement control module/SCR domain | 0 | Direct |
| Heat shock protein 90, HSP90, N-terminal domain | 0 | Direct |
| Sec63 N-terminal domain | 0 | Direct |
| Group II chaperonin (CCT, TRIC), apical domain | 0 | Direct |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Insulin-like | 0 | Direct |
| beta 1,4 galactosyltransferase (b4GalT1) | 0 | Direct |
| Pyk2-associated protein beta ARF-GAP domain | 0 | Direct |
| YbiA-like | 0 | Direct |
| Alcohol dehydrogenase-like, C-terminal domain | 0 | Direct |
| HD domain | 0 | Direct |
| DEP domain | 0 | Direct |
| Carbonic anhydrase | 0 | Direct |
| MOSC N-terminal domain-like | 0 | Direct |
| Methionine aminopeptidase, insert domain | 0 | Direct |
| NHL repeat | 0 | Direct |
| POU-specific domain | 0 | Direct |
| NTF2-like | 0 | Direct |
| Skp1 dimerisation domain-like | 0 | Direct |
| Acylamino-acid-releasing enzyme, C-terminal donain | 0 | Direct |
| YihX-like | 0 | Direct |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | Direct |
| WWE domain | 0 | Direct |
| ALDH-like | 0 | Direct |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
| L-aminoacid/polyamine oxidase | 0 | Direct |
| Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain | 0 | Direct |
| Troponin I | 0 | Direct |
| Purine and uridine phosphorylases | 0 | Direct |
| Pleckstrin-homology domain (PH domain) | 0 | Direct |
| UDP-glucose pyrophosphorylase | 0 | Direct |
| Glycosyl transferases group 1 | 0 | Direct |
| Phosphate binding protein-like | 0 | Direct |
| Proteasome subunits | 0 | Direct |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
| PDEase | 0 | Direct |
| Erythroid transcription factor GATA-1 | 0 | Direct |
| Spectrin repeat | 0 | Direct |
| SWIB/MDM2 domain | 0 | Direct |
| Phoshoinositide 3-kinase (PI3K) helical domain | 0 | Direct |
| Glycerol kinase | 0 | Direct |
| Thiolase-related | 0 | Direct |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | Direct |
| DPP6 catalytic domain-like | 0 | Direct |
| WGR domain | 0 | Direct |
| Translational machinery components | 0 | Direct |
| Ras-binding domain, RBD | 0 | Direct |
| LEM domain | 0 | Direct |
| GAS2 domain | 0 | Direct |
| MIR domain | 0 | Direct |
| Nucleoside diphosphate kinase, NDK | 0 | Direct |
| Cation efflux protein cytoplasmic domain-like | 0 | Direct |
| Dimeric isocitrate & isopropylmalate dehydrogenases | 0 | Direct |
| Fatty acid binding protein-like | 0 | Direct |
| D-aminoacid oxidase, N-terminal domain | 0 | Direct |
| Reductases | 0 | Direct |
| GYF domain | 0 | Direct |
| Polo-box duplicated region | 0 | Direct |
| MIF4G domain-like | 0 | Direct |
| Bactericidal permeability-increasing protein, BPI | 0 | Direct |
| Group II chaperonin (CCT, TRIC), ATPase domain | 0 | Direct |
| alpha-mannosidase | 0 | Direct |
| SCF ubiquitin ligase complex WHB domain | 0 | Direct |
| Armadillo repeat | 0 | Direct |
| Clathrin adaptor core protein | 0 | Direct |
| Proprotein convertase P-domain | 0 | Direct |
| Adenosine/AMP deaminase | 0 | Direct |
| Acireductone dioxygenase | 0 | Direct |
| HCDH C-domain-like | 0 | Direct |
| DNA replication initiator (cdc21/cdc54) N-terminal domain | 0 | Direct |
| First domain of FERM | 0 | Direct |
| Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | Direct |
| acyl-CoA oxidase C-terminal domains | 0 | Direct |
| Poly(ADP-ribose) polymerase, C-terminal domain | 0 | Direct |
| YicI catalytic domain-like | 0 | Direct |
| Medium chain acyl-CoA dehydrogenase-like, C-terminal domain | 0 | Direct |
| Cell cycle control phosphatase, catalytic domain | 0 | Direct |
| FF domain | 0 | Direct |
| Transducin (alpha subunit), insertion domain | 0 | Direct |
| Cyclin | 0 | Direct |
| cAMP-binding domain | 0 | Direct |
| Third domain of FERM | 0 | Direct |
| PurM C-terminal domain-like | 0 | Direct |
| Lamin A/C globular tail domain | 0 | Direct |
| Epoxide hydrolase | 0 | Direct |
| Anticodon-binding domain of Class II aaRS | 0 | Direct |
| Domain of poly(ADP-ribose) polymerase | 0 | Direct |
| Alcohol dehydrogenase-like, N-terminal domain | 0 | Direct |
| Acyl-carrier protein (ACP) | 0 | Direct |
| Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | Direct |
| Biotinyl/lipoyl-carrier proteins and domains | 0 | Direct |
| CRAL/TRIO N-terminal domain | 0 | Direct |
| BC C-terminal domain-like | 0 | Direct |
| Zn-finger domain of Sec23/24 | 0 | Direct |
| Lipovitellin-phosvitin complex, superhelical domain | 0 | Direct |
| Ubiquitin activating enzymes (UBA) | 0 | Direct |
| PABC (PABP) domain | 0 | Direct |
| Phosphoglucomutase, first 3 domains | 0 | Direct |
| Quinoprotein alcohol dehydrogenase-like | 0 | Direct |
| Annexin | 0 | Direct |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
| DNA gyrase/MutL, N-terminal domain | 0 | Direct |
| Hydantoinase (dihydropyrimidinase), catalytic domain | 0 | Direct |
| PDI-like | 0 | Direct |
| DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
| Small-conductance potassium channel | 0 | Direct |
| Calcium ATPase, transmembrane domain M | 0 | Direct |
| Gamma-glutamyltranspeptidase-like | 0 | Direct |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | Direct |
| VHS domain | 0 | Direct |
| ATP-dependent protease Lon (La), catalytic domain | 0 | Direct |
| COMT-like | 0 | Direct |
| Doublecortin (DC) | 0 | Direct |
| Adenain-like | 0 | Direct |
| BAR domain | 0 | Direct |
| SMAD domain | 0 | Direct |
| AN1-like Zinc finger | 0 | Direct |
| Profilin (actin-binding protein) | 0 | Direct |
| Reprolysin-like | 0 | Direct |
| Cadherin | 0 | Direct |
| Ribokinase-like | 0 | Direct |
| Glycerophosphoryl diester phosphodiesterase | 0 | Direct |
| PUA domain | 0 | Direct |
| Poly(A) polymerase, PAP, N-terminal domain | 0 | Direct |
| DPP6 N-terminal domain-like | 0 | Direct |
| alpha-mannosidase, domain 2 | 0 | Direct |
| SAM (sterile alpha motif) domain | 0 | Direct |
| Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain | 0 | Direct |
| Pancreatic carboxypeptidase, activation domain | 0 | Direct |
| Tubulin, GTPase domain | 0 | Direct |
| BC ATP-binding domain-like | 0 | Direct |
| PaaI/YdiI-like | 0 | Direct |
| Inositol polyphosphate kinase (IPK) | 0 | Direct |
| Ribonucleotide reductase-like | 0 | Direct |
| Protein prenyltransferases | 0 | Direct |
| Heme-dependent catalases | 0 | Direct |
| Class II glutamine amidotransferases | 0 | Direct |
| Translation initiation factor eIF4e | 0 | Direct |
| Laminin G-like module | 0 | Direct |
| Band 7/SPFH domain | 0 | Direct |
| HSP20 | 0 | Direct |
| Ngr ectodomain-like | 0 | Direct |
| a tRNA synthase domain | 0 | Direct |
| HEAT repeat | 0 | Direct |
| SMAD MH1 domain | 0 | Direct |
| LacY-like proton/sugar symporter | 0 | Direct |
| FAD-dependent thiol oxidase | 0 | Direct |
| Glycogenin | 0 | Direct |
| Arylsulfatase | 0 | Direct |
| RecA protein-like (ATPase-domain) | 0 | Direct |
| HAT/Suf repeat | 0 | Direct |
| beta-Lactamase/D-ala carboxypeptidase | 0 | Direct |
| Tim10/DDP | 0 | Direct |
| La domain | 0 | Direct |
| DEATH domain, DD | 0 | Direct |
| Inositol monophosphatase/fructose-1,6-bisphosphatase-like | 0 | Direct |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | Direct |
| CUT domain | 0 | Direct |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
| Poly(A) polymerase, PAP, C-terminal domain | 0 | Direct |
| Paired domain | 0 | Direct |
| Branched-chain alpha-keto acid dehydrogenase PP module | 0 | Direct |
| D-aminoacid oxidase-like | 0 | Direct |
| Ribosomal protein L1 | 0 | Direct |
| Tubulin, C-terminal domain | 0 | Direct |
| Chaperone J-domain | 0 | Direct |
| DNA repair protein MutS, domain III | 0 | Direct |
| Second domain of FERM | 0 | Direct |
| HSP90 C-terminal domain | 0 | Direct |
| Ran binding protein zinc finger-like | 0 | Direct |
| Anticodon-binding domain | 0 | Direct |
| Phosphatidylethanolamine binding protein | 0 | Direct |
| NOL1/NOP2/sun | 0 | Direct |
| Lactate & malate dehydrogenases, C-terminal domain | 0 | Direct |
| Pancreatic carboxypeptidases | 0 | Direct |
| CoA-binding domain | 0 | Direct |
| t-snare proteins | 0 | Direct |
| L30e/L7ae ribosomal proteins | 0 | Direct |
| alpha-mannosidase, C-terminal domain | 0 | Direct |
| AAT-like | 0 | Direct |
| Aquaporin-like | 0 | Direct |
| RNA-polymerase beta | 0 | Direct |
| XPF/Rad1/Mus81 nuclease | 0 | Direct |
| Cullin homology domain | 0 | Direct |
| F1F0 ATP synthase subunit C | 0 | Direct |
| PurM N-terminal domain-like | 0 | Direct |
| Matrix metalloproteases, catalytic domain | 0 | Direct |
| YWTD domain | 0 | Direct |
| PhzC/PhzF-like | 0 | Direct |
| Surp module (SWAP domain) | 0 | Direct |
| Filamin repeat (rod domain) | 0 | Direct |
| Mammalian PLC | 0 | Direct |
| S-adenosylmethionine synthetase | 0 | Direct |
| Sec63 C-terminal domain-like | 0 | Direct |
| Regulator of G-protein signaling, RGS | 0 | Direct |
| Actin/HSP70 | 0 | Direct |
| Hydantoinase (dihydropyrimidinase) | 0 | Direct |
| Ferredoxin reductase FAD-binding domain-like | 0 | Direct |
| 28-residue LRR | 0 | Direct |
| Formate/glycerate dehydrogenases, NAD-domain | 0 | Direct |
| Cu,Zn superoxide dismutase-like | 0 | Direct |
| Phoshoinositide 3-kinase (PI3K), catalytic domain | 0 | Direct |
| Amylase, catalytic domain | 0 | Direct |
| Myeloperoxidase-like | 0 | Direct |
| Arginine methyltransferase | 0 | Direct |
| Poly(A) polymerase, PAP, middle domain | 0 | Direct |
| Chromo domain | 0 | Direct |
| Oxysterol-binding protein | 0 | Direct |
| CAT-like | 0 | Direct |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Sterol carrier protein, SCP | 0 | Direct |
| ets domain | 0 | Direct |
| Internalin LRR domain | 0 | Direct |
| Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | Direct |
| Calpain large subunit, catalytic domain (domain II) | 0 | Direct |
| Hypothetical protein c14orf129, hspc210 | 0 | Direct |
| GAPDH-like | 0 | Direct |
| Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain | 0 | Direct |
| Trunk domain of Sec23/24 | 0 | Direct |
| Integrin domains | 0 | Direct |
| Choline kinase | 0 | Direct |
| 1,3-glucuronyltransferase | 0 | Direct |
| Cdc48 domain 2-like | 0 | Direct |
| Smc hinge domain | 0 | Direct |
| Intermediate filament protein, coiled coil region | 0 | Direct |
| Pepsin inhibitor-3 | 0 | Direct |
| Cofilin-like | 0 | Direct |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
| ValRS/IleRS/LeuRS editing domain | 0 | Direct |
| FtsH protease domain-like | 0 | Direct |
| RNA editing terminal uridyl transferase 2, RET2, domain 2 | 0 | Direct |
| RhoGDI-like | 0 | Direct |
| Branched-chain alpha-keto acid dehydrogenase Pyr module | 0 | Direct |
| Phosphoribosyltransferases (PRTases) | 0 | Direct |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | Direct |
| BC N-terminal domain-like | 0 | Direct |
| Sec7 domain | 0 | Direct |
| Lesion bypass DNA polymerase (Y-family), catalytic domain | 0 | Direct |
| Glutaminase | 0 | Direct |
| Class I glutamine amidotransferases (GAT) | 0 | Direct |
| Acyl-CoA thioesterase | 0 | Direct |
| FHA domain | 0 | Direct |
| p120GAP domain-like | 0 | Direct |
| Tetraspanin | 0 | Direct |
| LDH N-terminal domain-like | 0 | Direct |
| MutT-like | 0 | Direct |
| DNA gyrase/MutL, second domain | 0 | Direct |
| Hsp90 middle domain | 0 | Direct |
| Phosphotyrosine-binding domain (PTB) | 0 | Direct |
| Glycolipid transfer protein, GLTP | 0 | Direct |
| Elafin-like | 0 | Direct |
| beta-sandwich domain of Sec23/24 | 0 | Direct |
| Arfaptin, Rac-binding fragment | 0 | Direct |
| Citrate synthase | 0 | Direct |
| Linker histone H1/H5 | 0 | Direct |
| alpha-Amylases, C-terminal beta-sheet domain | 0 | Direct |
| Single strand DNA-binding domain, SSB | 0 | Direct |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
| U-box | 0 | Direct |
| Bacterial exopeptidase dimerisation domain | 0 | Direct |
| Clathrin coat assembly domain | 0 | Direct |
| 2Fe-2S ferredoxin domains from multidomain proteins | 0 | Direct |
| Nucleosome core histones | 0 | Direct |
| Clc chloride channel | 0 | Direct |
| Myotubularin-like phosphatases | 0 | Direct |
| AMPK-beta glycogen binding domain-like | 0 | Direct |
| CO dehydrogenase ISP C-domain like | 0 | Direct |
| Type II DNA topoisomerase | 0 | Direct |
| ARID domain | 0 | Direct |
| SWIRM domain | 0 | Direct |
| HSP40/DnaJ peptide-binding domain | 0 | Direct |
| SAND domain | 0 | Direct |
| Transducin (heterotrimeric G protein), gamma chain | 0 | Direct |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
| Tandem AAA-ATPase domain | 0.0003226 | Direct |
| Protein kinases, catalytic subunit | 0.01091 | Inherited |
| G proteins | 0.03566 | Inherited |
| Homeodomain | 0.03756 | Inherited |
| WD40-repeat | 0.04776 | Inherited |
| PDZ domain | 0.06423 | Inherited |
| MSP-like | 0.06681 | Inherited |
| SH2 domain | 0.06969 | Inherited |
| L-arabinose binding protein-like | 0.07068 | Inherited |
| Acetyl-CoA synthetase-like | 0.08526 | Inherited |
| Calponin-homology domain, CH-domain | 0.08526 | Inherited |
| Canonical RBD | 0.09247 | Inherited |
| CCCH zinc finger | 0.1029 | Inherited |
| ABC transporter ATPase domain-like | 0.1052 | Inherited |
| Tetratricopeptide repeat (TPR) | 0.1403 | Inherited |
| Cold shock DNA-binding domain-like | 0.1501 | Inherited |
| Adenylyl and guanylyl cyclase catalytic domain | 0.1628 | Inherited |
| HLH, helix-loop-helix DNA-binding domain | 0.1628 | Inherited |
| Calcium ATPase, transduction domain A | 0.1981 | Inherited |
| SH3-domain | 0.2285 | Inherited |
| Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain | 0.2377 | Inherited |
| DBL homology domain (DH-domain) | 0.2377 | Inherited |
| Pepsin-like | 0.2377 | Inherited |
| Histone lysine methyltransferases | 0.2377 | Inherited |
| Extended PAW domain | 0.2377 | Inherited |
| Elongation factors | 0.2377 | Inherited |
| Class I aminoacyl-tRNA synthetases (RS), catalytic domain | 0.2377 | Inherited |
| Acetylcholinesterase-like | 0.2564 | Inherited |
| Dual specificity phosphatase-like | 0.2603 | Inherited |
| HMG-box | 0.2603 | Inherited |
| EGF-type module | 0.2846 | Inherited |
| Metal cation-transporting ATPase, ATP-binding domain N | 0.2846 | Inherited |
| Ankyrin repeat | 0.2977 | Inherited |
| Extended AAA-ATPase domain | 0.3045 | Inherited |
| Multidrug efflux transporter AcrB transmembrane domain | 0.3062 | Inherited |
| Bromodomain | 0.3111 | Inherited |
| FYVE, a phosphatidylinositol-3-phosphate binding domain | 0.3111 | Inherited |
| 6-phosphogluconate dehydrogenase-like, N-terminal domain | 0.3111 | Inherited |
| Cytochrome P450 | 0.3254 | Inherited |
| FAD/NAD-linked reductases, N-terminal and central domains | 0.3407 | Inherited |
| Crotonase-like | 0.373 | Inherited |
| Sm motif of small nuclear ribonucleoproteins, SNRNP | 0.373 | Inherited |
| Meta-cation ATPase, catalytic domain P | 0.373 | Inherited |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.402 | Inherited |
| Pumilio repeat | 0.4439 | Inherited |
| GABA-aminotransferase-like | 0.4439 | Inherited |
| FKBP immunophilin/proline isomerase | 0.458 | Inherited |
| ABC transporter transmembrane region | 0.4662 | Inherited |
| Protein kinase cysteine-rich domain (cys2, phorbol-binding domain) | 0.4767 | Inherited |
| Cation efflux protein transmembrane domain-like | 0.4831 | Inherited |
| Glutathione S-transferase (GST), N-terminal domain | 0.5087 | Inherited |
| Hect, E3 ligase catalytic domain | 0.5274 | Inherited |
| Myosin rod fragments | 0.5274 | Inherited |
| Pyridoxal-dependent decarboxylase | 0.5274 | Inherited |
| Nicotinic receptor ligand binding domain-like | 0.5362 | Inherited |
| I set domains | 0.5666 | Inherited |
| Gastric lipase | 0.5726 | Inherited |
| Myb/SANT domain | 0.5726 | Inherited |
| Calpain large subunit, middle domain (domain III) | 0.5726 | Inherited |
| Papain-like | 0.5854 | Inherited |
| WW domain | 0.5987 | Inherited |
| Class I alpha-1;2-mannosidase, catalytic domain | 0.6242 | Inherited |
| UBC-related | 0.6394 | Inherited |
| Synaptotagmin-like (S variant) | 0.6669 | Inherited |
| Osmotin, thaumatin-like protein | 0.6782 | Inherited |
| Ubiquitin carboxyl-terminal hydrolase, UCH | 0.6925 | Inherited |
| BTB/POZ domain | 0.7037 | Inherited |
| EF-hand modules in multidomain proteins | 0.7376 | Inherited |
| Frizzled cysteine-rich domain | 0.7376 | Inherited |
| Transforming growth factor (TGF)-beta | 0.7376 | Inherited |
| PHD domain | 0.7668 | Inherited |
| Cdc48 N-terminal domain-like | 0.8021 | Inherited |
| H-NOX domain | 0.8021 | Inherited |
| Bacterial lipase | 0.8021 | Inherited |
| MIT domain | 0.8021 | Inherited |
| Ubiquitin-related | 0.8031 | Inherited |
| Voltage-gated potassium channels | 0.8104 | Inherited |
| FAD-linked reductases, N-terminal domain | 0.8433 | Inherited |
| PAZ domain | 0.8679 | Inherited |
| LIM domain | 0.8802 | Inherited |
| Fibronectin type III | 0.8926 | Inherited |
| Glutathione S-transferase (GST), C-terminal domain | 0.9105 | Inherited |
| Leucine zipper domain | 0.919 | Inherited |
| DnaQ-like 3'-5' exonuclease | 0.9274 | Inherited |
| Nuclear receptor ligand-binding domain | 0.942 | Inherited |
| Calmodulin-like | 0.9424 | Inherited |
| Ribonuclease PH domain 1-like | 0.9772 | Inherited |
| Ribonuclease PH domain 2-like | 0.9772 | Inherited |
| NagD-like | 0.9772 | Inherited |
| Glutathione peroxidase-like | 1 | Inherited |
| RING finger domain, C3HC4 | 1 | Inherited |
| B-box zinc-binding domain | 1 | Inherited |
| Cyclophilin (peptidylprolyl isomerase) | 1 | Inherited |
| Choline/Carnitine O-acyltransferase | 1 | Inherited |
| Nuclear receptor | 1 | Inherited |
| F-box domain | 1 | Inherited |
| Rhodopsin-like | 1 | Inherited |
| C-type lectin domain | 1 | Inherited |
| N-acetyl transferase, NAT | 1 | Inherited |
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A presence/absence matrix is generated using protein domain
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Supra-domain (including individual superfamily)
(show details)
Supra-domains annotated to this WP term (Not in SPWP)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
| PurM C-terminal domain-like | 0 | DIRECT |
| VPS9 domain | 0 | DIRECT |
| cAMP-binding domain-like | 0 | DIRECT |
| Protease propeptides/inhibitors | 0 | DIRECT |
| Terpenoid cyclases/Protein prenyltransferases | 0 | DIRECT |
| Isocitrate/Isopropylmalate dehydrogenase-like | 0 | DIRECT |
| Profilin (actin-binding protein) | 0 | DIRECT |
| Purine and uridine phosphorylases | 0 | DIRECT |
| SCP-like | 0 | DIRECT |
| Smc hinge domain | 0 | DIRECT |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
| Cystatin/monellin | 0 | DIRECT |
| Cytochrome c | 0 | DIRECT |
| Kringle-like | 0 | DIRECT |
| Second domain of FERM | 0 | DIRECT |
| Formate/glycerate dehydrogenase catalytic domain-like | 0 | DIRECT |
| lambda repressor-like DNA-binding domains | 0 | DIRECT |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
| DEATH domain | 0 | DIRECT |
| Pepsin inhibitor-3 | 0 | DIRECT |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | DIRECT |
| Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | DIRECT |
| ThrRS/AlaRS common domain | 0 | DIRECT |
| Tubulin C-terminal domain-like | 0 | DIRECT |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
| Fibrinogen C-terminal domain-like | 0 | DIRECT |
| Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
| 2Fe-2S ferredoxin-like | 0 | DIRECT |
| Doublecortin (DC) | 0 | DIRECT |
| Subdomain of clathrin and coatomer appendage domain | 0 | DIRECT |
| PIN domain-like | 0 | DIRECT |
| Terpenoid synthases | 0 | DIRECT |
| beta-lactamase/transpeptidase-like | 0 | DIRECT |
| Zn-finger domain of Sec23/24 | 0 | DIRECT |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
| L-aspartase-like | 0 | DIRECT |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
| Class I glutamine amidotransferase-like | 0 | DIRECT |
| PEBP-like | 0 | DIRECT |
| PLP-binding barrel | 0 | DIRECT |
| Ribosomal protein S10 | 0 | DIRECT |
| Galactose mutarotase-like | 0 | DIRECT |
| Chitinase insertion domain | 0 | DIRECT |
| PLC-like phosphodiesterases | 0 | DIRECT |
| Subtilisin-like | 0 | DIRECT |
| ValRS/IleRS/LeuRS editing domain | 0 | DIRECT |
| Band 7/SPFH domain | 0 | DIRECT |
| Putative DNA-binding domain | 0 | DIRECT |
| Sec1/munc18-like (SM) proteins | 0 | DIRECT |
| GroEL equatorial domain-like | 0 | DIRECT |
| PreATP-grasp domain | 0 | DIRECT |
| Translational machinery components | 0 | DIRECT |
| BEACH domain | 0 | DIRECT |
| Ran binding protein zinc finger-like | 0 | DIRECT |
| Integrin alpha N-terminal domain | 0 | DIRECT |
| Bacterial exopeptidase dimerisation domain | 0 | DIRECT |
| Glutathione synthetase ATP-binding domain-like | 0 | DIRECT |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | DIRECT |
| dsRNA-binding domain-like | 0 | DIRECT |
| Single hybrid motif | 0 | DIRECT |
| Clathrin adaptor appendage domain | 0 | DIRECT |
| PYP-like sensor domain (PAS domain) | 0 | DIRECT |
| Annexin | 0 | DIRECT |
| Pentein | 0 | DIRECT |
| Blood coagulation inhibitor (disintegrin) | 0 | DIRECT |
| HSP20-like chaperones | 0 | DIRECT |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | DIRECT |
| Activating enzymes of the ubiquitin-like proteins | 0 | DIRECT |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0 | DIRECT |
| Phosphoenolpyruvate/pyruvate domain | 0 | DIRECT |
| GAT-like domain | 0 | DIRECT |
| 3-carboxy-cis,cis-mucoante lactonizing enzyme | 0 | DIRECT |
| Hedgehog/intein (Hint) domain | 0 | DIRECT |
| Transducin (alpha subunit), insertion domain | 0 | DIRECT |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Cullin homology domain | 0 | DIRECT |
| LDH C-terminal domain-like | 0 | DIRECT |
| t-snare proteins | 0 | DIRECT |
| SPOC domain-like | 0 | DIRECT |
| Rudiment single hybrid motif | 0 | DIRECT |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | DIRECT |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | DIRECT |
| ALDH-like | 0 | DIRECT |
| Nucleoside diphosphate kinase, NDK | 0 | DIRECT |
| Tricorn protease domain 2 | 0 | DIRECT |
| SMAD MH1 domain | 0 | DIRECT |
| Surp module (SWAP domain) | 0 | DIRECT |
| Skp1 dimerisation domain-like | 0 | DIRECT |
| PHM/PNGase F | 0 | DIRECT |
| Tubby C-terminal domain-like | 0 | DIRECT |
| Acyl-CoA dehydrogenase NM domain-like | 0 | DIRECT |
| Nucleotidyltransferase | 0 | DIRECT |
| PK beta-barrel domain-like | 0 | DIRECT |
| FF domain | 0 | DIRECT |
| Thyroglobulin type-1 domain | 0 | DIRECT |
| Invertebrate chitin-binding proteins | 0 | DIRECT |
| alpha-catenin/vinculin-like | 0 | DIRECT |
| GroES-like | 0 | DIRECT |
| Domain of poly(ADP-ribose) polymerase | 0 | DIRECT |
| DNA repair protein MutS, domain III | 0 | DIRECT |
| Aminoacid dehydrogenase-like, N-terminal domain | 0 | DIRECT |
| MOSC N-terminal domain-like | 0 | DIRECT |
| LysM domain | 0 | DIRECT |
| Cdc48 domain 2-like | 0 | DIRECT |
| Chromo domain-like | 0 | DIRECT |
| Tim10-like | 0 | DIRECT |
| YWTD domain | 0 | DIRECT |
| CBD9-like | 0 | DIRECT |
| TK C-terminal domain-like | 0 | DIRECT |
| Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
| Type II DNA topoisomerase | 0 | DIRECT |
| SAICAR synthase-like | 0 | DIRECT |
| Phoshotransferase/anion transport protein | 0 | DIRECT |
| Lipovitellin-phosvitin complex, superhelical domain | 0 | DIRECT |
| Ribosomal L27 protein-like | 0 | DIRECT |
| Cu,Zn superoxide dismutase-like | 0 | DIRECT |
| Transducin (heterotrimeric G protein), gamma chain | 0 | DIRECT |
| Families 57/38 glycoside transferase middle domain | 0 | DIRECT |
| Carbonic anhydrase | 0 | DIRECT |
| F1F0 ATP synthase subunit C | 0 | DIRECT |
| L30e-like | 0 | DIRECT |
| Rap/Ran-GAP | 0 | DIRECT |
| Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | DIRECT |
| Molybdenum cofactor-binding domain | 0 | DIRECT |
| MgtE membrane domain-like | 0 | DIRECT |
| Ribosomal protein L1 | 0 | DIRECT |
| Nucleoporin domain | 0 | DIRECT |
| Nop domain | 0 | DIRECT |
| alpha/beta knot | 0 | DIRECT |
| RBP11-like subunits of RNA polymerase | 0 | DIRECT |
| Troponin coil-coiled subunits | 0 | DIRECT |
| Ribokinase-like | 0 | DIRECT |
| Cadherin-like | 0 | DIRECT |
| Small-conductance potassium channel | 0 | DIRECT |
| Aquaporin-like | 0 | DIRECT |
| Cation efflux protein cytoplasmic domain-like | 0 | DIRECT |
| GYF domain | 0 | DIRECT |
| GroEL apical domain-like | 0 | DIRECT |
| Succinyl-CoA synthetase domains | 0 | DIRECT |
| Hormone receptor domain | 0 | DIRECT |
| PAP/OAS1 substrate-binding domain | 0 | DIRECT |
| FAD-dependent thiol oxidase | 0 | DIRECT |
| PUA domain-like | 0 | DIRECT |
| FtsH protease domain-like | 0 | DIRECT |
| SIS domain | 0 | DIRECT |
| Lamin A/C globular tail domain | 0 | DIRECT |
| Restriction endonuclease-like | 0 | DIRECT |
| Radical SAM enzymes | 0 | DIRECT |
| Citrate synthase | 0 | DIRECT |
| MFPT repeat-like | 0 | DIRECT |
| ENTH/VHS domain | 0 | DIRECT |
| JAB1/MPN domain | 0 | DIRECT |
| Zn-binding ribosomal proteins | 0 | DIRECT |
| WGR domain-like | 0 | DIRECT |
| Helical domain of Sec23/24 | 0 | DIRECT |
| Hypothetical protein c14orf129, hspc210 | 0 | DIRECT |
| Carboxypeptidase regulatory domain-like | 0 | DIRECT |
| Tubulin nucleotide-binding domain-like | 0 | DIRECT |
| Ribulose-phoshate binding barrel | 0 | DIRECT |
| SWIB/MDM2 domain | 0 | DIRECT |
| PGBD-like | 0 | DIRECT |
| Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | DIRECT |
| Arginase/deacetylase | 0 | DIRECT |
| Carbohydrate phosphatase | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
| Heme-dependent catalase-like | 0 | DIRECT |
| eIF4e-like | 0 | DIRECT |
| Oxysterol-binding protein-like | 0 | DIRECT |
| Insulin-like | 0 | DIRECT |
| Complement control module/SCR domain | 0 | DIRECT |
| Glycolipid transfer protein, GLTP | 0 | DIRECT |
| CAD & PB1 domains | 0 | DIRECT |
| Ribosomal protein L10-like | 0 | DIRECT |
| HSP90 C-terminal domain | 0 | DIRECT |
| Cullin repeat-like | 0 | DIRECT |
| AN1-like Zinc finger | 0 | DIRECT |
| Aldolase | 0 | DIRECT |
| SAND domain-like | 0 | DIRECT |
| WWE domain | 0 | DIRECT |
| Elafin-like | 0 | DIRECT |
| LEM domain | 0 | DIRECT |
| ISP domain | 0 | DIRECT |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | DIRECT |
| Mitochondrial carrier | 0 | DIRECT |
| Creatinase/prolidase N-terminal domain | 0 | DIRECT |
| CO dehydrogenase molybdoprotein N-domain-like | 0 | DIRECT |
| DNA ligase/mRNA capping enzyme, catalytic domain | 0 | DIRECT |
| Periplasmic binding protein-like II | 0 | DIRECT |
| Acid phosphatase/Vanadium-dependent haloperoxidase | 0 | DIRECT |
| Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0 | DIRECT |
| ARID-like | 0 | DIRECT |
| Spectrin repeat | 0 | DIRECT |
| Clc chloride channel | 0 | DIRECT |
| TGS-like | 0 | DIRECT |
| CRAL/TRIO N-terminal domain | 0 | DIRECT |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Class II aaRS ABD-related | 0 | DIRECT |
| Ferritin-like | 0 | DIRECT |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
| MIR domain | 0 | DIRECT |
| PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | DIRECT |
| Galactose oxidase, central domain | 0 | DIRECT |
| Diaminopimelate epimerase-like | 0 | DIRECT |
| Actin-like ATPase domain | 0 | DIRECT |
| GAS2 domain-like | 0 | DIRECT |
| Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
| PEP carboxykinase-like | 0 | DIRECT |
| PurM N-terminal domain-like | 0 | DIRECT |
| Sec63 N-terminal domain-like | 0 | DIRECT |
| HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
| ArfGap/RecO-like zinc finger | 0 | DIRECT |
| Phosphoglucomutase, first 3 domains | 0 | DIRECT |
| YbiA-like | 0 | DIRECT |
| Polo-box domain | 0 | DIRECT |
| PEP carboxykinase N-terminal domain | 0 | DIRECT |
| DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
| Thiamin diphosphate-binding fold (THDP-binding) | 0 | DIRECT |
| GroEL-intermediate domain like | 0 | DIRECT |
| Outer arm dynein light chain 1 | 0 | DIRECT |
| PABC (PABP) domain | 0 | DIRECT |
| Heme-dependent peroxidases | 0 | DIRECT |
| Intermediate filament protein, coiled coil region | 0 | DIRECT |
| ADP-ribosylation | 0 | DIRECT |
| Ribosomal proteins S24e, L23 and L15e | 0 | DIRECT |
| HCP-like | 0 | DIRECT |
| R3H domain | 0 | DIRECT |
| Chaperone J-domain | 0 | DIRECT |
| 14-3-3 protein | 0 | DIRECT |
| Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
| Sec7 domain | 0 | DIRECT |
| Thiolase-like | 0 | DIRECT |
| S-adenosylmethionine synthetase | 0 | DIRECT |
| CO dehydrogenase ISP C-domain like | 0 | DIRECT |
| Proton glutamate symport protein | 0 | DIRECT |
| Carbon-nitrogen hydrolase | 0 | DIRECT |
| Integrin domains | 0 | DIRECT |
| P-loop containing nucleoside triphosphate hydrolases | 0.0000001124 | DIRECT |
| PH domain-like | 0.000041 | DIRECT |
| Histone-fold | 0.0001047 | DIRECT |
| Protein kinase-like (PK-like) | 0.003324 | INHERITED FROM: drug induced gene expression variant || kinase activity reduced || protein phosphorylation variant || alkaline pH chemotaxis variant || organism environmental stimulus response variant || life span variant || metal response variant || chemical response variant || protein subcellular localization variant || pathogen induced gene expression variant || organism osmostic stress hypersensitive || transgene expression reduced || lipid synthesis increased || mechanosensation variant || aldicarb response variant || conflicting sensory integration variant || colchicine resistant || egg laying response to food variant || protein expression variant || anoxia resistant || positive chemotaxis variant || second messenger mediated signaling variant || octanol chemotaxis defective || protein phosphorylation reduced |
| TPR-like | 0.01555 | INHERITED FROM: chemotaxis variant || dauer defective || associative learning variant || light body touch resistant || positive chemotaxis defective |
| Periplasmic binding protein-like I | 0.01705 | INHERITED FROM: AWC odorant chemotaxis defective || benzaldehyde chemotaxis variant || magnesium chemotaxis defective || iodide chemotaxis variant || chemotaxis variant || iodide chemotaxis defective || chemosensory response variant || AWC odorant chemotaxis variant || alkaline pH chemotaxis variant || carbon dioxide avoidance variant || organism environmental stimulus response variant || aqueous chemosensory response variant || chemical response variant || response to food variant || mechanosensation variant || bromide chemotaxis variant || memory retention defective || aqueous positive chemotaxis variant || lithium chemotaxis defective || positive chemotaxis variant || bromide chemotaxis defective || second messenger mediated signaling variant || diacetyl chemotaxis variant |
| PapD-like | 0.02508 | INHERITED FROM: developmental growth variant || dauer lifespan variant || fat content variant || larval arrest || lipid metabolism variant || larval growth variant || slow growth || dauer metabolism variant || dauer lifespan extended |
| ARM repeat | 0.03018 | INHERITED FROM: sick || RNAi response variant || gene expression variant || organism hypersensitive ionizing radiation || protein expression variant || organism metabolism processing variant |
| SH2 domain | 0.03995 | INHERITED FROM: acetylcholinesterase inhibitor resistant || aldicarb resistant || level of protein expression variant || protein expression variant || protein expression reduced |
| "Winged helix" DNA-binding domain | 0.04161 | INHERITED FROM: chemical hypersensitive || shortened life span || spontaneous mutation rate increased || life span variant || protein aggregation induced behavior variant || germline transgene silencing variant || protein protein interaction variant || anesthetic response variant || organism hypertonic lethality increased || paraquat hypersensitive || protein expression increased || protein aggregation variant || organism metabolism processing variant || growth rate variant |
| PDZ domain-like | 0.04332 | INHERITED FROM: drug resistant || acetylcholinesterase inhibitor response variant || drug response variant || aldicarb response variant || protein expression variant |
| Homeodomain-like | 0.04932 | INHERITED FROM: ectopic expression transgene || inhibitor of serotonin uptake variant || sexually dimorphic physiology variant || protein degradation variant || carbon dioxide avoidance variant || egg laying imipramine resistant || adrenergic receptor antagonist response variant || imipramine resistant || carbon dioxide response variant || organism metabolism processing variant || growth rate variant || level of transgene expression variant |
| WD40 repeat-like | 0.05883 | INHERITED FROM: antimicrobial gene expression variant || protein aggregation induced behavior variant || late larval arrest || protein protein interaction variant || early larval arrest || osmotic avoidance variant || protein aggregation variant || organism metabolism processing variant |
| Nucleic acid-binding proteins | 0.05997 | INHERITED FROM: hypoxia resistant || sick || nonsense mRNA accumulation || hydroxyurea hypersensitive || hydroxyurea response variant || mRNA surveillance defective |
| Calponin-homology domain, CH-domain | 0.06216 | INHERITED FROM: protein degradation variant || protein expression variant |
| Acetyl-CoA synthetase-like | 0.06216 | INHERITED FROM: lipid metabolism variant |
| Cyclin-like | 0.06914 | INHERITED FROM: protein phosphorylation variant || protein phosphorylation reduced |
| CCCH zinc finger | 0.07688 | INHERITED FROM: ectopic expression transgene || mRNA expression ectopic || gene expression variant || transgene expression variant || organism metabolism processing variant |
| Translation proteins | 0.09506 | INHERITED FROM: mRNA levels increased || proteasome core activity variant || protein phosphorylation variant || sick || protein protein interaction variant || gene expression variant || transgene expression variant || protein aggregation variant || organism metabolism processing variant || protein phosphorylation increased |
| Galactose-binding domain-like | 0.09834 | INHERITED FROM: protein interaction variant || protein protein interaction variant || protein aggregation variant |
| HLH, helix-loop-helix DNA-binding domain | 0.1167 | INHERITED FROM: ectopic expression transgene || RNA expression variant || lysine chemotaxis defective || fungal resistance increased || pathogen resistance increased || aqueous positive chemotaxis defective || hypoxia response variant || gene expression level reduced || organism metabolism processing variant |
| Nucleotide cyclase | 0.1167 | INHERITED FROM: AWC odorant chemotaxis defective || magnesium chemotaxis defective || iodide chemotaxis variant || chemotaxis variant || iodide chemotaxis defective || chemosensory response variant || AWC odorant chemotaxis variant || alkaline pH chemotaxis variant || anion positive chemotaxis variant || anion positive chemotaxis defective || organism environmental stimulus response variant || cation positive chemotaxis variant || osmotic avoidance variant || bromide chemotaxis variant || carbon dioxide response variant || cation positive chemotaxis defective || lithium chemotaxis defective || positive chemotaxis variant || bromide chemotaxis defective || second messenger mediated signaling variant || diacetyl chemotaxis variant |
| Acid proteases | 0.1172 | INHERITED FROM: transgene subcellular localization variant || hypoosmotic shock hypersensitive || protein interaction variant || protein protein interaction variant || gene expression variant || osmotic integrity variant || transgene expression variant || protein aggregation variant || organism metabolism processing variant |
| SMAD/FHA domain | 0.1172 | INHERITED FROM: aldicarb response variant |
| Calcium ATPase, transmembrane domain M | 0.1301 | INHERITED FROM: nicotine hypersensitive || organism environmental stimulus response variant || lipid composition variant |
| Regulator of G-protein signaling, RGS | 0.1443 | INHERITED FROM: chemotaxis variant || mechanosensation variant || negative chemotaxis variant |
| Metal cation-transporting ATPase, ATP-binding domain N | 0.1443 | INHERITED FROM: nicotine hypersensitive || organism environmental stimulus response variant || lipid composition variant |
| SH3-domain | 0.1533 | INHERITED FROM: protein phosphorylation variant || aldicarb response variant || protein expression variant || protein expression reduced |
| E set domains | 0.156 | INHERITED FROM: paraquat hypersensitive |
| Calcium ATPase, transduction domain A | 0.1603 | INHERITED FROM: nicotine hypersensitive || organism environmental stimulus response variant |
| EGF/Laminin | 0.1619 | INHERITED FROM: odorant negative chemotaxis defective || octanol chemotaxis variant || negative chemotaxis variant || octanol chemotaxis defective |
| Quinoprotein alcohol dehydrogenase-like | 0.1777 | INHERITED FROM: mid larval arrest || mRNA levels increased || protein degradation variant || hypoxia response variant || protein metabolism variant || L2 arrest |
| Ankyrin repeat | 0.1784 | INHERITED FROM: chemotaxis variant || chemosensory response variant || odorant negative chemotaxis defective || organism heat response variant || mechanosensation variant || octanol chemotaxis variant || octanol chemotaxis defective |
| Multidrug efflux transporter AcrB transmembrane domain | 0.1917 | INHERITED FROM: chemotaxis variant || egg integrity defective early emb || odorant positive chemotaxis defective || embryo osmotic integrity defective early emb || odorant chemosensory response variant || positive chemotaxis defective |
| DBL homology domain (DH-domain) | 0.1968 | INHERITED FROM: bacterially unswollen || protein degradation variant || pathogen resistance increased || organism environmental stimulus response variant || aldicarb response variant || organism pathogen response variant |
| HMG-box | 0.2182 | INHERITED FROM: maintenance of gene silencing variant || transgene expression variant |
| ClpP/crotonase | 0.2182 | INHERITED FROM: fat content variant || lipid metabolism variant || level of transgene expression variant |
| Cytochrome P450 | 0.2182 | INHERITED FROM: metal response variant || cadmium response variant |
| (Trans)glycosidases | 0.2182 | INHERITED FROM: pathogen susceptibility increased || pathogen load variant |
| POZ domain | 0.2555 | INHERITED FROM: chemical hypersensitive || protein aggregation induced behavior variant || early larval arrest || resistant to protein aggregation induced paralysis || L1 arrest |
| RNA-binding domain, RBD | 0.2664 | INHERITED FROM: RNA expression variant || no induction of antimicrobial peptide expression after infection || sick || antimicrobial gene expression variant || mRNA export variant || innate immune response variant || RNA processing variant || maintenance of gene silencing variant || alternative splicing variant || starvation induced apoptosis variant || organism metabolism processing variant |
| Bromodomain | 0.2671 | INHERITED FROM: sick || drug adaptation variant || acute functional tolerance to alcohol defective || anesthetic resistant || ethanol resistant || anesthetic response variant || organism UV hypersensitive || organism UV response variant |
| 6-phosphogluconate dehydrogenase C-terminal domain-like | 0.2671 | INHERITED FROM: fat content variant || lipid metabolism variant |
| RNI-like | 0.2674 | INHERITED FROM: resistant to protein aggregation induced paralysis |
| Cysteine proteinases | 0.2711 | INHERITED FROM: hypoosmotic shock hypersensitive || pattern of transgene expression variant || protein interaction variant || protein protein interaction variant || osmotic integrity variant || paraquat hypersensitive || organism metabolism processing variant |
| UDP-Glycosyltransferase/glycogen phosphorylase | 0.2735 | INHERITED FROM: organism osmotic stress response variant |
| SNARE-like | 0.295 | INHERITED FROM: sick || acetylcholinesterase inhibitor resistant || transgene subcellular localization variant || pattern of transgene expression variant || aldicarb resistant || acetylcholinesterase inhibitor response variant || gene expression variant || transgene expression variant || protein metabolism variant || aldicarb response variant || organism metabolism processing variant |
| ABC transporter transmembrane region | 0.2965 | INHERITED FROM: RNAi response variant || organism environmental stimulus response variant || metal response variant || colchicine hypersensitive || cadmium response variant |
| Lipocalins | 0.3059 | INHERITED FROM: fat content variant || lipid metabolism variant || fat content increased || paraquat hypersensitive |
| Cation efflux protein transmembrane domain-like | 0.3606 | INHERITED FROM: manganese toxicity resistant || metal response variant || manganese response variant || cadmium hypersensitive |
| Translation proteins SH3-like domain | 0.3606 | INHERITED FROM: protein protein interaction variant || early larval arrest || gene expression variant || transgene expression variant || protein aggregation variant || organism metabolism processing variant |
| Nicotinic receptor ligand binding domain-like | 0.3707 | INHERITED FROM: nicotine resistant || selenium response variant || organism environmental stimulus response variant || hypoosmotic shock hypersensitive || ivermectin resistant || ivermectin response variant || slowing response on food variant || aqueous chemosensory response variant || chemical response variant || cholinergic agonist resistant || antihelmintic response variant || mechanosensation variant || sodium chloride chemotaxis variant || drug response variant || DMPP response variant |
| Ubiquitin-like | 0.3877 | INHERITED FROM: heteroplasmy || protein interaction variant || protein protein interaction variant || protein aggregation variant || organism metabolism processing variant |
| Cysteine-rich domain | 0.4022 | INHERITED FROM: drug induced gene expression variant || bacterially unswollen || antimicrobial gene expression variant || acetylcholinesterase inhibitor response variant || protein subcellular localization variant || odorant positive chemotaxis variant || aldicarb response variant || organism pathogen response variant || organism metabolism processing variant || odorant chemosensory response variant || positive chemotaxis variant |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.4078 | INHERITED FROM: nicotine resistant || selenium response variant || protein degradation variant || organism environmental stimulus response variant || hypoosmotic shock hypersensitive || ivermectin resistant || ivermectin response variant || slowing response on food variant || aqueous chemosensory response variant || chemical response variant || cholinergic agonist resistant || antihelmintic response variant || mechanosensation variant || sodium chloride chemotaxis variant || drug response variant || positive chemotaxis variant || DMPP response variant |
| FKBP-like | 0.4093 | INHERITED FROM: transgene subcellular localization variant || pattern of transgene expression variant || protein interaction variant || protein protein interaction variant || protein aggregation variant |
| Class II aaRS and biotin synthetases | 0.469 | INHERITED FROM: oxygen response variant || hypoxia resistant || organism environmental stimulus response variant || hypoxia response variant || gene expression variant || transgene expression variant || organism metabolism processing variant |
| Myosin rod fragments | 0.4824 | INHERITED FROM: drug resistant |
| DHS-like NAD/FAD-binding domain | 0.4824 | INHERITED FROM: life span variant || protein acetylation variant || protein modification variant |
| Hect, E3 ligase catalytic domain | 0.4824 | INHERITED FROM: transgene subcellular localization variant || organism environmental stimulus response variant || protein aggregation induced behavior variant || pattern of transgene expression variant || protein interaction variant || protein protein interaction variant || gene expression variant || transgene expression variant || protein aggregation variant || organism metabolism processing variant |
| PRTase-like | 0.4824 | INHERITED FROM: drug resistant || Fluorouracil resistant |
| BRCT domain | 0.5019 | INHERITED FROM: organism ionizing radiation response variant |
| FYVE/PHD zinc finger | 0.5206 | INHERITED FROM: ectopic expression transgene || protein modification variant || organism UV hypersensitive || organism UV response variant || protein methylation variant |
| Ribosomal protein S5 domain 2-like | 0.5242 | INHERITED FROM: early larval arrest || transgene expression variant |
| Riboflavin synthase domain-like | 0.5314 | INHERITED FROM: pattern protein expression variant |
| Ferredoxin reductase-like, C-terminal NADP-linked domain | 0.5314 | INHERITED FROM: pattern protein expression variant |
| Calpain large subunit, middle domain (domain III) | 0.5314 | INHERITED FROM: protein degradation variant || metabolic pathway variant || protein metabolism variant |
| FAD-linked reductases, C-terminal domain | 0.5345 | INHERITED FROM: life span variant |
| Sm-like ribonucleoproteins | 0.5345 | INHERITED FROM: sick || life span variant || pattern of transgene expression variant || protein subcellular localization variant || organism heat response variant || gene expression variant || transgene expression variant || unfolded protein response variant |
| Cystine-knot cytokines | 0.5345 | INHERITED FROM: levamisole response variant || nicotine response variant |
| WW domain | 0.5345 | INHERITED FROM: acetylcholinesterase inhibitor resistant || aldicarb resistant || maintenance of gene silencing variant |
| Voltage-gated potassium channels | 0.5369 | INHERITED FROM: protein degradation variant || serotonin response variant || adrenergic receptor antagonist response variant || metabolic pathway variant || serotonin resistant || mechanosensation variant || protein metabolism variant || growth rate variant || positive chemotaxis defective |
| Nucleotidylyl transferase | 0.5589 | INHERITED FROM: paraquat resistant || oxygen response variant || hypoxia resistant || antimicrobial gene expression variant || organism environmental stimulus response variant || innate immune response variant || hypoxia response variant || transgene expression increased || organism metabolism processing variant |
| FAD/NAD(P)-binding domain | 0.5619 | INHERITED FROM: life span variant || ATP levels variant || pesticide response variant || ATP levels reduced |
| SET domain | 0.5711 | INHERITED FROM: dosage compensation variant || shortened life span || RNAi response variant || spontaneous mutation rate increased || ectopic expression antibody || life span variant || histone methylation variant || protein modification variant || maintenance of gene silencing variant || somatic transgene silencing variant || protein expression variant || protein methylation variant |
| Seven-hairpin glycosidases | 0.5819 | INHERITED FROM: extended life span || protein protein interaction variant || protein aggregation variant |
| SAM/Pointed domain | 0.5843 | INHERITED FROM: aldicarb response variant |
| Growth factor receptor domain | 0.5843 | INHERITED FROM: protein degradation variant |
| UBC-like | 0.5951 | INHERITED FROM: sick || transgene subcellular localization variant || late larval arrest || pattern of transgene expression variant || protein interaction variant || protein protein interaction variant || protein aggregation variant || organism metabolism processing variant |
| Multidrug resistance efflux transporter EmrE | 0.6025 | INHERITED FROM: bacterially unswollen || pathogen resistance increased |
| HAD-like | 0.6082 | INHERITED FROM: nicotine hypersensitive |
| Nucleotide-binding domain | 0.6398 | INHERITED FROM: extended life span || life span variant |
| KA1-like | 0.6398 | INHERITED FROM: RNA expression variant |
| Osmotin, thaumatin-like protein | 0.6398 | INHERITED FROM: metal response variant || transgene expression reduced || cadmium response variant || cadmium hypersensitive |
| MFS general substrate transporter | 0.6674 | INHERITED FROM: organism high sodium chloride hypersensitive |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0.6704 | INHERITED FROM: drug induced gene expression variant || antimicrobial gene expression variant || RNAi response variant || drug resistant || nose touch variant || organism environmental stimulus response variant || chemical response variant || metabolic pathway variant || protein subcellular localization variant || egg laying serotonin variant || aging variant || protein expression variant || growth rate variant |
| Glucocorticoid receptor-like (DNA-binding domain) | 0.6783 | INHERITED FROM: dauer resistance to harsh conditions variant || fat content increased || transgene expression reduced || gene expression level reduced || gene expression level high || SDS sensitive dauer || level of transgene expression variant |
| GST C-terminal domain-like | 0.6941 | INHERITED FROM: enzyme activity reduced || organism stress response variant || organism environmental stimulus response variant || organism electrophilic stress hypersensitive || organism heat hypersensitive || cadmium response variant || cadmium hypersensitive || enzyme activity variant |
| Frizzled cysteine-rich domain | 0.7038 | INHERITED FROM: antibody staining variant || transgene expression reduced |
| S15/NS1 RNA-binding domain | 0.7038 | INHERITED FROM: transgene expression increased |
| 4Fe-4S ferredoxins | 0.7038 | INHERITED FROM: extended life span |
| Ribonuclease H-like | 0.7331 | INHERITED FROM: RNA expression variant || RNAi response variant || 21U RNA expression variant || siRNA expression variant || maintenance of gene silencing variant || somatic transgene silencing variant || RNAi enhanced |
| PAZ domain | 0.7487 | INHERITED FROM: mRNA levels increased || RNA expression variant || RNAi response variant || 21U RNA expression variant || siRNA expression variant || maintenance of gene silencing variant || somatic transgene silencing variant || RNAi enhanced |
| ADC-like | 0.7719 | INHERITED FROM: protein interaction variant || protein protein interaction variant || metabolic pathway variant || protein metabolism variant || protein aggregation variant || level of transgene expression variant |
| MIT domain | 0.7719 | INHERITED FROM: protein interaction variant || protein protein interaction variant || protein aggregation variant |
| alpha/beta-Hydrolases | 0.8033 | INHERITED FROM: acetylcholinesterase activity variant || acetylcholinesterase reduced |
| Fibronectin type III | 0.8122 | INHERITED FROM: protein degradation variant || growth rate variant |
| Clavaminate synthase-like | 0.8474 | INHERITED FROM: life span variant || histone methylation variant || organism temperature response variant || protein methylation variant |
| EF-hand | 0.8505 | INHERITED FROM: protein interaction variant || protein aggregation variant |
| Leucine zipper domain | 0.861 | INHERITED FROM: mRNA levels reduced || mRNA expression variant || pore forming toxin response variant || pathogen susceptibility increased || transgene expression reduced || level of transgene expression variant |
| GTPase activation domain, GAP | 0.8696 | INHERITED FROM: protein expression variant |
| UBA-like | 0.8723 | INHERITED FROM: protein protein interaction variant || protein aggregation variant |
| DNA/RNA polymerases | 0.9376 | INHERITED FROM: DNA repair variant || DNA metabolism variant |
| p53-like transcription factors | 0.943 | INHERITED FROM: ectopic expression transgene || gene expression level reduced || level of transgene expression variant |
| Ribonuclease PH domain 2-like | 0.9537 | INHERITED FROM: early larval arrest |
| Thioredoxin-like | 0.9635 | INHERITED FROM: enzyme activity reduced || organism stress response variant || organism environmental stimulus response variant || organism electrophilic stress hypersensitive || organism heat hypersensitive || paraquat response variant || cadmium hypersensitive || enzyme activity variant |
| Immunoglobulin | 0.9643 | INHERITED FROM: protein degradation variant || aldicarb response variant || growth rate variant |
| Nuclear receptor ligand-binding domain | 0.9687 | INHERITED FROM: dauer resistance to harsh conditions variant || lipid metabolism variant || fat content increased || transgene expression reduced || gene expression level reduced || gene expression level high || SDS sensitive dauer || level of transgene expression variant |
| Eukaryotic type KH-domain (KH-domain type I) | 0.9992 | INHERITED FROM: RNA expression variant |
| Family A G protein-coupled receptor-like | 1 | INHERITED FROM: serotonin induced pumping variant || locomotion rate serotonin variant || male tail curling serotonin variant || serotonin induced fat reduction variant |
| F-box domain | 1 | INHERITED FROM: resistant to protein aggregation induced paralysis |
| Cyclophilin-like | 1 | INHERITED FROM: transgene subcellular localization variant || pattern of transgene expression variant || protein interaction variant || protein protein interaction variant || gene expression variant || transgene expression variant || protein aggregation variant || organism metabolism processing variant |
| CoA-dependent acyltransferases | 1 | INHERITED FROM: lipid metabolism variant |
| Ligand-binding domain in the NO signalling and Golgi transport | 1 | INHERITED FROM: carbon dioxide avoidance variant || carbon dioxide response variant |
| RING/U-box | 1 | INHERITED FROM: transgene subcellular localization variant || pattern of transgene expression variant || protein interaction variant || protein protein interaction variant || gene expression variant || transgene expression variant || protein aggregation variant || organism metabolism processing variant |
| beta-beta-alpha zinc fingers | 1 | INHERITED FROM: inhibitor of serotonin uptake variant || egg laying imipramine resistant || egg laying serotonin resistant || imipramine resistant || organism metabolism processing variant |
| Saposin | 1 | INHERITED FROM: transgene expression reduced || increased pathogen survival || level of transgene expression variant || pathogen load variant |
| Bet v1-like | 1 | INHERITED FROM: growth rate variant |
| B-box zinc-binding domain | 1 | INHERITED FROM: transgene subcellular localization variant || protein interaction variant || protein protein interaction variant || gene expression variant || transgene expression variant || protein aggregation variant || organism metabolism processing variant |
| Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
| PurM C-terminal domain-like | 0 | Direct |
| VPS9 domain | 0 | Direct |
| cAMP-binding domain-like | 0 | Direct |
| Protease propeptides/inhibitors | 0 | Direct |
| Terpenoid cyclases/Protein prenyltransferases | 0 | Direct |
| Isocitrate/Isopropylmalate dehydrogenase-like | 0 | Direct |
| Profilin (actin-binding protein) | 0 | Direct |
| Purine and uridine phosphorylases | 0 | Direct |
| SCP-like | 0 | Direct |
| Smc hinge domain | 0 | Direct |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
| Cystatin/monellin | 0 | Direct |
| Cytochrome c | 0 | Direct |
| Kringle-like | 0 | Direct |
| Second domain of FERM | 0 | Direct |
| Formate/glycerate dehydrogenase catalytic domain-like | 0 | Direct |
| lambda repressor-like DNA-binding domains | 0 | Direct |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
| DEATH domain | 0 | Direct |
| Pepsin inhibitor-3 | 0 | Direct |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | Direct |
| Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | Direct |
| ThrRS/AlaRS common domain | 0 | Direct |
| Tubulin C-terminal domain-like | 0 | Direct |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
| Fibrinogen C-terminal domain-like | 0 | Direct |
| Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | Direct |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
| 2Fe-2S ferredoxin-like | 0 | Direct |
| Doublecortin (DC) | 0 | Direct |
| Subdomain of clathrin and coatomer appendage domain | 0 | Direct |
| PIN domain-like | 0 | Direct |
| Terpenoid synthases | 0 | Direct |
| beta-lactamase/transpeptidase-like | 0 | Direct |
| Zn-finger domain of Sec23/24 | 0 | Direct |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
| L-aspartase-like | 0 | Direct |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
| Class I glutamine amidotransferase-like | 0 | Direct |
| PEBP-like | 0 | Direct |
| PLP-binding barrel | 0 | Direct |
| Ribosomal protein S10 | 0 | Direct |
| Galactose mutarotase-like | 0 | Direct |
| Chitinase insertion domain | 0 | Direct |
| PLC-like phosphodiesterases | 0 | Direct |
| Subtilisin-like | 0 | Direct |
| ValRS/IleRS/LeuRS editing domain | 0 | Direct |
| Band 7/SPFH domain | 0 | Direct |
| Putative DNA-binding domain | 0 | Direct |
| Sec1/munc18-like (SM) proteins | 0 | Direct |
| GroEL equatorial domain-like | 0 | Direct |
| PreATP-grasp domain | 0 | Direct |
| Translational machinery components | 0 | Direct |
| BEACH domain | 0 | Direct |
| Ran binding protein zinc finger-like | 0 | Direct |
| Integrin alpha N-terminal domain | 0 | Direct |
| Bacterial exopeptidase dimerisation domain | 0 | Direct |
| Glutathione synthetase ATP-binding domain-like | 0 | Direct |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | Direct |
| dsRNA-binding domain-like | 0 | Direct |
| Single hybrid motif | 0 | Direct |
| Clathrin adaptor appendage domain | 0 | Direct |
| PYP-like sensor domain (PAS domain) | 0 | Direct |
| Annexin | 0 | Direct |
| Pentein | 0 | Direct |
| Blood coagulation inhibitor (disintegrin) | 0 | Direct |
| HSP20-like chaperones | 0 | Direct |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | Direct |
| Activating enzymes of the ubiquitin-like proteins | 0 | Direct |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0 | Direct |
| Phosphoenolpyruvate/pyruvate domain | 0 | Direct |
| GAT-like domain | 0 | Direct |
| 3-carboxy-cis,cis-mucoante lactonizing enzyme | 0 | Direct |
| Hedgehog/intein (Hint) domain | 0 | Direct |
| Transducin (alpha subunit), insertion domain | 0 | Direct |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Cullin homology domain | 0 | Direct |
| LDH C-terminal domain-like | 0 | Direct |
| t-snare proteins | 0 | Direct |
| SPOC domain-like | 0 | Direct |
| Rudiment single hybrid motif | 0 | Direct |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | Direct |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | Direct |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | Direct |
| ALDH-like | 0 | Direct |
| Nucleoside diphosphate kinase, NDK | 0 | Direct |
| Tricorn protease domain 2 | 0 | Direct |
| SMAD MH1 domain | 0 | Direct |
| Surp module (SWAP domain) | 0 | Direct |
| Skp1 dimerisation domain-like | 0 | Direct |
| PHM/PNGase F | 0 | Direct |
| Tubby C-terminal domain-like | 0 | Direct |
| Acyl-CoA dehydrogenase NM domain-like | 0 | Direct |
| Nucleotidyltransferase | 0 | Direct |
| PK beta-barrel domain-like | 0 | Direct |
| FF domain | 0 | Direct |
| Thyroglobulin type-1 domain | 0 | Direct |
| Invertebrate chitin-binding proteins | 0 | Direct |
| alpha-catenin/vinculin-like | 0 | Direct |
| GroES-like | 0 | Direct |
| Domain of poly(ADP-ribose) polymerase | 0 | Direct |
| DNA repair protein MutS, domain III | 0 | Direct |
| Aminoacid dehydrogenase-like, N-terminal domain | 0 | Direct |
| MOSC N-terminal domain-like | 0 | Direct |
| LysM domain | 0 | Direct |
| Cdc48 domain 2-like | 0 | Direct |
| Chromo domain-like | 0 | Direct |
| Tim10-like | 0 | Direct |
| YWTD domain | 0 | Direct |
| CBD9-like | 0 | Direct |
| TK C-terminal domain-like | 0 | Direct |
| Composite domain of metallo-dependent hydrolases | 0 | Direct |
| Type II DNA topoisomerase | 0 | Direct |
| SAICAR synthase-like | 0 | Direct |
| Phoshotransferase/anion transport protein | 0 | Direct |
| Lipovitellin-phosvitin complex, superhelical domain | 0 | Direct |
| Ribosomal L27 protein-like | 0 | Direct |
| Cu,Zn superoxide dismutase-like | 0 | Direct |
| Transducin (heterotrimeric G protein), gamma chain | 0 | Direct |
| Families 57/38 glycoside transferase middle domain | 0 | Direct |
| Carbonic anhydrase | 0 | Direct |
| F1F0 ATP synthase subunit C | 0 | Direct |
| L30e-like | 0 | Direct |
| Rap/Ran-GAP | 0 | Direct |
| Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | Direct |
| Molybdenum cofactor-binding domain | 0 | Direct |
| MgtE membrane domain-like | 0 | Direct |
| Ribosomal protein L1 | 0 | Direct |
| Nucleoporin domain | 0 | Direct |
| Nop domain | 0 | Direct |
| alpha/beta knot | 0 | Direct |
| RBP11-like subunits of RNA polymerase | 0 | Direct |
| Troponin coil-coiled subunits | 0 | Direct |
| Ribokinase-like | 0 | Direct |
| Cadherin-like | 0 | Direct |
| Small-conductance potassium channel | 0 | Direct |
| Aquaporin-like | 0 | Direct |
| Cation efflux protein cytoplasmic domain-like | 0 | Direct |
| GYF domain | 0 | Direct |
| GroEL apical domain-like | 0 | Direct |
| Succinyl-CoA synthetase domains | 0 | Direct |
| Hormone receptor domain | 0 | Direct |
| PAP/OAS1 substrate-binding domain | 0 | Direct |
| FAD-dependent thiol oxidase | 0 | Direct |
| PUA domain-like | 0 | Direct |
| FtsH protease domain-like | 0 | Direct |
| SIS domain | 0 | Direct |
| Lamin A/C globular tail domain | 0 | Direct |
| Restriction endonuclease-like | 0 | Direct |
| Radical SAM enzymes | 0 | Direct |
| Citrate synthase | 0 | Direct |
| MFPT repeat-like | 0 | Direct |
| ENTH/VHS domain | 0 | Direct |
| JAB1/MPN domain | 0 | Direct |
| Zn-binding ribosomal proteins | 0 | Direct |
| WGR domain-like | 0 | Direct |
| Helical domain of Sec23/24 | 0 | Direct |
| Hypothetical protein c14orf129, hspc210 | 0 | Direct |
| Carboxypeptidase regulatory domain-like | 0 | Direct |
| Tubulin nucleotide-binding domain-like | 0 | Direct |
| Ribulose-phoshate binding barrel | 0 | Direct |
| SWIB/MDM2 domain | 0 | Direct |
| PGBD-like | 0 | Direct |
| Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | Direct |
| Arginase/deacetylase | 0 | Direct |
| Carbohydrate phosphatase | 0 | Direct |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
| Heme-dependent catalase-like | 0 | Direct |
| eIF4e-like | 0 | Direct |
| Oxysterol-binding protein-like | 0 | Direct |
| Insulin-like | 0 | Direct |
| Complement control module/SCR domain | 0 | Direct |
| Glycolipid transfer protein, GLTP | 0 | Direct |
| CAD & PB1 domains | 0 | Direct |
| Ribosomal protein L10-like | 0 | Direct |
| HSP90 C-terminal domain | 0 | Direct |
| Cullin repeat-like | 0 | Direct |
| AN1-like Zinc finger | 0 | Direct |
| Aldolase | 0 | Direct |
| SAND domain-like | 0 | Direct |
| WWE domain | 0 | Direct |
| Elafin-like | 0 | Direct |
| LEM domain | 0 | Direct |
| ISP domain | 0 | Direct |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | Direct |
| Mitochondrial carrier | 0 | Direct |
| Creatinase/prolidase N-terminal domain | 0 | Direct |
| CO dehydrogenase molybdoprotein N-domain-like | 0 | Direct |
| DNA ligase/mRNA capping enzyme, catalytic domain | 0 | Direct |
| Periplasmic binding protein-like II | 0 | Direct |
| Acid phosphatase/Vanadium-dependent haloperoxidase | 0 | Direct |
| Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0 | Direct |
| ARID-like | 0 | Direct |
| Spectrin repeat | 0 | Direct |
| Clc chloride channel | 0 | Direct |
| TGS-like | 0 | Direct |
| CRAL/TRIO N-terminal domain | 0 | Direct |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Class II aaRS ABD-related | 0 | Direct |
| Ferritin-like | 0 | Direct |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
| MIR domain | 0 | Direct |
| PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | Direct |
| Galactose oxidase, central domain | 0 | Direct |
| Diaminopimelate epimerase-like | 0 | Direct |
| Actin-like ATPase domain | 0 | Direct |
| GAS2 domain-like | 0 | Direct |
| Phosphoglucomutase, C-terminal domain | 0 | Direct |
| PEP carboxykinase-like | 0 | Direct |
| PurM N-terminal domain-like | 0 | Direct |
| Sec63 N-terminal domain-like | 0 | Direct |
| HSP40/DnaJ peptide-binding domain | 0 | Direct |
| ArfGap/RecO-like zinc finger | 0 | Direct |
| Phosphoglucomutase, first 3 domains | 0 | Direct |
| YbiA-like | 0 | Direct |
| Polo-box domain | 0 | Direct |
| PEP carboxykinase N-terminal domain | 0 | Direct |
| DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
| Thiamin diphosphate-binding fold (THDP-binding) | 0 | Direct |
| GroEL-intermediate domain like | 0 | Direct |
| Outer arm dynein light chain 1 | 0 | Direct |
| PABC (PABP) domain | 0 | Direct |
| Heme-dependent peroxidases | 0 | Direct |
| Intermediate filament protein, coiled coil region | 0 | Direct |
| ADP-ribosylation | 0 | Direct |
| Ribosomal proteins S24e, L23 and L15e | 0 | Direct |
| HCP-like | 0 | Direct |
| R3H domain | 0 | Direct |
| Chaperone J-domain | 0 | Direct |
| 14-3-3 protein | 0 | Direct |
| Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
| Sec7 domain | 0 | Direct |
| Thiolase-like | 0 | Direct |
| S-adenosylmethionine synthetase | 0 | Direct |
| CO dehydrogenase ISP C-domain like | 0 | Direct |
| Proton glutamate symport protein | 0 | Direct |
| Carbon-nitrogen hydrolase | 0 | Direct |
| Integrin domains | 0 | Direct |
| P-loop containing nucleoside triphosphate hydrolases | 0.0000001124 | Direct |
| PH domain-like | 0.000041 | Direct |
| Histone-fold | 0.0001047 | Direct |
| Protein kinase-like (PK-like) | 0.003324 | Inherited |
| TPR-like | 0.01555 | Inherited |
| Periplasmic binding protein-like I | 0.01705 | Inherited |
| PapD-like | 0.02508 | Inherited |
| ARM repeat | 0.03018 | Inherited |
| SH2 domain | 0.03995 | Inherited |
| "Winged helix" DNA-binding domain | 0.04161 | Inherited |
| PDZ domain-like | 0.04332 | Inherited |
| Homeodomain-like | 0.04932 | Inherited |
| WD40 repeat-like | 0.05883 | Inherited |
| Nucleic acid-binding proteins | 0.05997 | Inherited |
| Calponin-homology domain, CH-domain | 0.06216 | Inherited |
| Acetyl-CoA synthetase-like | 0.06216 | Inherited |
| Cyclin-like | 0.06914 | Inherited |
| CCCH zinc finger | 0.07688 | Inherited |
| Translation proteins | 0.09506 | Inherited |
| Galactose-binding domain-like | 0.09834 | Inherited |
| HLH, helix-loop-helix DNA-binding domain | 0.1167 | Inherited |
| Nucleotide cyclase | 0.1167 | Inherited |
| Acid proteases | 0.1172 | Inherited |
| SMAD/FHA domain | 0.1172 | Inherited |
| Calcium ATPase, transmembrane domain M | 0.1301 | Inherited |
| Regulator of G-protein signaling, RGS | 0.1443 | Inherited |
| Metal cation-transporting ATPase, ATP-binding domain N | 0.1443 | Inherited |
| SH3-domain | 0.1533 | Inherited |
| E set domains | 0.156 | Inherited |
| Calcium ATPase, transduction domain A | 0.1603 | Inherited |
| EGF/Laminin | 0.1619 | Inherited |
| Quinoprotein alcohol dehydrogenase-like | 0.1777 | Inherited |
| Ankyrin repeat | 0.1784 | Inherited |
| Multidrug efflux transporter AcrB transmembrane domain | 0.1917 | Inherited |
| DBL homology domain (DH-domain) | 0.1968 | Inherited |
| HMG-box | 0.2182 | Inherited |
| ClpP/crotonase | 0.2182 | Inherited |
| Cytochrome P450 | 0.2182 | Inherited |
| (Trans)glycosidases | 0.2182 | Inherited |
| POZ domain | 0.2555 | Inherited |
| RNA-binding domain, RBD | 0.2664 | Inherited |
| Bromodomain | 0.2671 | Inherited |
| 6-phosphogluconate dehydrogenase C-terminal domain-like | 0.2671 | Inherited |
| RNI-like | 0.2674 | Inherited |
| Cysteine proteinases | 0.2711 | Inherited |
| UDP-Glycosyltransferase/glycogen phosphorylase | 0.2735 | Inherited |
| SNARE-like | 0.295 | Inherited |
| ABC transporter transmembrane region | 0.2965 | Inherited |
| Lipocalins | 0.3059 | Inherited |
| Cation efflux protein transmembrane domain-like | 0.3606 | Inherited |
| Translation proteins SH3-like domain | 0.3606 | Inherited |
| Nicotinic receptor ligand binding domain-like | 0.3707 | Inherited |
| Ubiquitin-like | 0.3877 | Inherited |
| Cysteine-rich domain | 0.4022 | Inherited |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.4078 | Inherited |
| FKBP-like | 0.4093 | Inherited |
| Class II aaRS and biotin synthetases | 0.469 | Inherited |
| Myosin rod fragments | 0.4824 | Inherited |
| DHS-like NAD/FAD-binding domain | 0.4824 | Inherited |
| Hect, E3 ligase catalytic domain | 0.4824 | Inherited |
| PRTase-like | 0.4824 | Inherited |
| BRCT domain | 0.5019 | Inherited |
| FYVE/PHD zinc finger | 0.5206 | Inherited |
| Ribosomal protein S5 domain 2-like | 0.5242 | Inherited |
| Riboflavin synthase domain-like | 0.5314 | Inherited |
| Ferredoxin reductase-like, C-terminal NADP-linked domain | 0.5314 | Inherited |
| Calpain large subunit, middle domain (domain III) | 0.5314 | Inherited |
| FAD-linked reductases, C-terminal domain | 0.5345 | Inherited |
| Sm-like ribonucleoproteins | 0.5345 | Inherited |
| Cystine-knot cytokines | 0.5345 | Inherited |
| WW domain | 0.5345 | Inherited |
| Voltage-gated potassium channels | 0.5369 | Inherited |
| Nucleotidylyl transferase | 0.5589 | Inherited |
| FAD/NAD(P)-binding domain | 0.5619 | Inherited |
| SET domain | 0.5711 | Inherited |
| Seven-hairpin glycosidases | 0.5819 | Inherited |
| SAM/Pointed domain | 0.5843 | Inherited |
| Growth factor receptor domain | 0.5843 | Inherited |
| UBC-like | 0.5951 | Inherited |
| Multidrug resistance efflux transporter EmrE | 0.6025 | Inherited |
| HAD-like | 0.6082 | Inherited |
| Nucleotide-binding domain | 0.6398 | Inherited |
| KA1-like | 0.6398 | Inherited |
| Osmotin, thaumatin-like protein | 0.6398 | Inherited |
| MFS general substrate transporter | 0.6674 | Inherited |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0.6704 | Inherited |
| Glucocorticoid receptor-like (DNA-binding domain) | 0.6783 | Inherited |
| GST C-terminal domain-like | 0.6941 | Inherited |
| Frizzled cysteine-rich domain | 0.7038 | Inherited |
| S15/NS1 RNA-binding domain | 0.7038 | Inherited |
| 4Fe-4S ferredoxins | 0.7038 | Inherited |
| Ribonuclease H-like | 0.7331 | Inherited |
| PAZ domain | 0.7487 | Inherited |
| ADC-like | 0.7719 | Inherited |
| MIT domain | 0.7719 | Inherited |
| alpha/beta-Hydrolases | 0.8033 | Inherited |
| Fibronectin type III | 0.8122 | Inherited |
| Clavaminate synthase-like | 0.8474 | Inherited |
| EF-hand | 0.8505 | Inherited |
| Leucine zipper domain | 0.861 | Inherited |
| GTPase activation domain, GAP | 0.8696 | Inherited |
| UBA-like | 0.8723 | Inherited |
| DNA/RNA polymerases | 0.9376 | Inherited |
| p53-like transcription factors | 0.943 | Inherited |
| Ribonuclease PH domain 2-like | 0.9537 | Inherited |
| Thioredoxin-like | 0.9635 | Inherited |
| Immunoglobulin | 0.9643 | Inherited |
| Nuclear receptor ligand-binding domain | 0.9687 | Inherited |
| Eukaryotic type KH-domain (KH-domain type I) | 0.9992 | Inherited |
| Family A G protein-coupled receptor-like | 1 | Inherited |
| F-box domain | 1 | Inherited |
| Cyclophilin-like | 1 | Inherited |
| CoA-dependent acyltransferases | 1 | Inherited |
| Ligand-binding domain in the NO signalling and Golgi transport | 1 | Inherited |
| RING/U-box | 1 | Inherited |
| beta-beta-alpha zinc fingers | 1 | Inherited |
| Saposin | 1 | Inherited |
| Bet v1-like | 1 | Inherited |
| B-box zinc-binding domain | 1 | Inherited |
(show details)
Supra-domains annotated to this WP term (Not in SPWP)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
48425,50729
48425 - Sec7 domain
50729 - PH domain-like | 0 | DIRECT |
53474,53474
53474 - alpha/beta-Hydrolases
53474 - alpha/beta-Hydrolases | 0 | DIRECT |
48592,54849
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like | 0 | DIRECT |
82615,82615
82615 - Polo-box domain
82615 - Polo-box domain | 0 | DIRECT |
48371,56112
48371 - ARM repeat
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
57184,57184
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | DIRECT |
82895,82895
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat | 0 | DIRECT |
57184,57196
57184 - Growth factor receptor domain
57196 - EGF/Laminin | 0 | DIRECT |
47954,47954
47954 - Cyclin-like
47954 - Cyclin-like | 0 | DIRECT |
49742,49742
49742 - PHM/PNGase F
49742 - PHM/PNGase F | 0 | DIRECT |
161111,160240
161111 - Cation efflux protein transmembrane domain-like
160240 - Cation efflux protein cytoplasmic domain-like | 0 | DIRECT |
51735,55347
51735 - NAD(P)-binding Rossmann-fold domains
55347 - Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | DIRECT |
50249,50249
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
50677,52374
50677 - ValRS/IleRS/LeuRS editing domain
52374 - Nucleotidylyl transferase | 0 | DIRECT |
56059,52210
56059 - Glutathione synthetase ATP-binding domain-like
52210 - Succinyl-CoA synthetase domains | 0 | DIRECT |
57196,57184
57196 - EGF/Laminin
57184 - Growth factor receptor domain | 0 | DIRECT |
74650,51445
74650 - Galactose mutarotase-like
51445 - (Trans)glycosidases | 0 | DIRECT |
54849,52029
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0 | DIRECT |
54695,81382
54695 - POZ domain
81382 - Skp1 dimerisation domain-like | 0 | DIRECT |
55681,52954
55681 - Class II aaRS and biotin synthetases
52954 - Class II aaRS ABD-related | 0 | DIRECT |
53187,49464
53187 - Zn-dependent exopeptidases
49464 - Carboxypeptidase regulatory domain-like | 0 | DIRECT |
57625,57625
57625 - Invertebrate chitin-binding proteins
57625 - Invertebrate chitin-binding proteins | 0 | DIRECT |
54534,54534
54534 - FKBP-like
54534 - FKBP-like | 0 | DIRECT |
50447,50465
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
57756,50630
57756 - Retrovirus zinc finger-like domains
50630 - Acid proteases | 0 | DIRECT |
53901,53901
53901 - Thiolase-like
53901 - Thiolase-like | 0 | DIRECT |
57889,48350
57889 - Cysteine-rich domain
48350 - GTPase activation domain, GAP | 0 | DIRECT |
49265,48726
49265 - Fibronectin type III
48726 - Immunoglobulin | 0 | DIRECT |
53187,55031
53187 - Zn-dependent exopeptidases
55031 - Bacterial exopeptidase dimerisation domain | 0 | DIRECT |
51905,55424
51905 - FAD/NAD(P)-binding domain
55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | DIRECT |
57535,57535
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | DIRECT |
81698,81698
81698 - FF domain
81698 - FF domain | 0 | DIRECT |
68923,53795
68923 - PEP carboxykinase N-terminal domain
53795 - PEP carboxykinase-like | 0 | DIRECT |
50729,56112
50729 - PH domain-like
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
51735,50129
51735 - NAD(P)-binding Rossmann-fold domains
50129 - GroES-like | 0 | DIRECT |
57889,50729
57889 - Cysteine-rich domain
50729 - PH domain-like | 0 | DIRECT |
49313,49313
49313 - Cadherin-like
49313 - Cadherin-like | 0 | DIRECT |
53738,53738
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains | 0 | DIRECT |
54160,54160
54160 - Chromo domain-like
54160 - Chromo domain-like | 0 | DIRECT |
75632,46785
75632 - Cullin homology domain
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
53067,100920
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
57362,57362
57362 - BPTI-like
57362 - BPTI-like | 0 | DIRECT |
51445,51445
51445 - (Trans)glycosidases
51445 - (Trans)glycosidases | 0 | DIRECT |
51445,54556
51445 - (Trans)glycosidases
54556 - Chitinase insertion domain | 0 | DIRECT |
54768,54768
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like | 0 | DIRECT |
48065,50729
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like | 0 | DIRECT |
52518,52922
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52922 - TK C-terminal domain-like | 0 | DIRECT |
88713,88688
88713 - Glycoside hydrolase/deacetylase
88688 - Families 57/38 glycoside transferase middle domain | 0 | DIRECT |
56645,47203
56645 - Acyl-CoA dehydrogenase NM domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
52518,52518
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52518 - Thiamin diphosphate-binding fold (THDP-binding) | 0 | DIRECT |
47576,47576
47576 - Calponin-homology domain, CH-domain
47576 - Calponin-homology domain, CH-domain | 0 | DIRECT |
50129,51735
50129 - GroES-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
55785,55785
55785 - PYP-like sensor domain (PAS domain)
55785 - PYP-like sensor domain (PAS domain) | 0 | DIRECT |
49562,48371
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat | 0 | DIRECT |
161093,161093
161093 - MgtE membrane domain-like
161093 - MgtE membrane domain-like | 0 | DIRECT |
81383,50978
81383 - F-box domain
50978 - WD40 repeat-like | 0 | DIRECT |
52540,140990
52540 - P-loop containing nucleoside triphosphate hydrolases
140990 - FtsH protease domain-like | 0 | DIRECT |
141673,50800
141673 - MOSC N-terminal domain-like
50800 - PK beta-barrel domain-like | 0 | DIRECT |
57850,117839
57850 - RING/U-box
117839 - WWE domain | 0 | DIRECT |
56059,51246
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 0 | DIRECT |
46966,46966
46966 - Spectrin repeat
46966 - Spectrin repeat | 0 | DIRECT |
47031,50729
47031 - Second domain of FERM
50729 - PH domain-like | 0 | DIRECT |
55874,54211
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
54211 - Ribosomal protein S5 domain 2-like | 0 | DIRECT |
52540,81271
52540 - P-loop containing nucleoside triphosphate hydrolases
81271 - TGS-like | 0 | DIRECT |
52283,51735
52283 - Formate/glycerate dehydrogenase catalytic domain-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
47413,46689
47413 - lambda repressor-like DNA-binding domains
46689 - Homeodomain-like | 0 | DIRECT |
51206,51206
51206 - cAMP-binding domain-like
51206 - cAMP-binding domain-like | 0 | DIRECT |
54665,56003
54665 - CO dehydrogenase molybdoprotein N-domain-like
56003 - Molybdenum cofactor-binding domain | 0 | DIRECT |
57903,82199
57903 - FYVE/PHD zinc finger
82199 - SET domain | 0 | DIRECT |
64356,49447
64356 - SNARE-like
49447 - Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
50044,50044
50044 - SH3-domain
50044 - SH3-domain | 0 | DIRECT |
57938,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
101690,53098
101690 - PAZ domain
53098 - Ribonuclease H-like | 0 | DIRECT |
54897,53187
54897 - Protease propeptides/inhibitors
53187 - Zn-dependent exopeptidases | 0 | DIRECT |
52540,90123
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region | 0 | DIRECT |
57196,49899
57196 - EGF/Laminin
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
52490,55307
52490 - Tubulin nucleotide-binding domain-like
55307 - Tubulin C-terminal domain-like | 0 | DIRECT |
50044,52540
50044 - SH3-domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
54585,52540
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
52374,47323
52374 - Nucleotidylyl transferase
47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
57863,48403
57863 - ArfGap/RecO-like zinc finger
48403 - Ankyrin repeat | 0 | DIRECT |
53067,53067
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 0 | DIRECT |
51971,54373
51971 - Nucleotide-binding domain
54373 - FAD-linked reductases, C-terminal domain | 0 | DIRECT |
57756,57756
57756 - Retrovirus zinc finger-like domains
57756 - Retrovirus zinc finger-like domains | 0 | DIRECT |
54001,49758
54001 - Cysteine proteinases
49758 - Calpain large subunit, middle domain (domain III) | 0 | DIRECT |
52540,46785
52540 - P-loop containing nucleoside triphosphate hydrolases
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
56601,48403
56601 - beta-lactamase/transpeptidase-like
48403 - Ankyrin repeat | 0 | DIRECT |
46938,52087
46938 - CRAL/TRIO N-terminal domain
52087 - CRAL/TRIO domain | 0 | DIRECT |
81324,81296
81324 - Voltage-gated potassium channels
81296 - E set domains | 0 | DIRECT |
55394,55394
55394 - Bactericidal permeability-increasing protein, BPI
55394 - Bactericidal permeability-increasing protein, BPI | 0 | DIRECT |
51735,56327
51735 - NAD(P)-binding Rossmann-fold domains
56327 - LDH C-terminal domain-like | 0 | DIRECT |
48179,48179
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | DIRECT |
56091,50249
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
56112,82615
56112 - Protein kinase-like (PK-like)
82615 - Polo-box domain | 0 | DIRECT |
90229,90229
90229 - CCCH zinc finger
90229 - CCCH zinc finger | 0 | DIRECT |
52743,49785
52743 - Subtilisin-like
49785 - Galactose-binding domain-like | 0 | DIRECT |
81811,82754
81811 - Helical domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
52113,52113
52113 - BRCT domain
52113 - BRCT domain | 0 | DIRECT |
56672,100879
56672 - DNA/RNA polymerases
100879 - Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
54236,54236
54236 - Ubiquitin-like
54236 - Ubiquitin-like | 0 | DIRECT |
48334,52540
48334 - DNA repair protein MutS, domain III
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
54897,52743
54897 - Protease propeptides/inhibitors
52743 - Subtilisin-like | 0 | DIRECT |
55486,50923
55486 - Metalloproteases ("zincins"), catalytic domain
50923 - Hemopexin-like domain | 0 | DIRECT |
51445,51011
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain | 0 | DIRECT |
81333,81333
81333 - F1F0 ATP synthase subunit C
81333 - F1F0 ATP synthase subunit C | 0 | DIRECT |
56968,48431
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
48431 - Lipovitellin-phosvitin complex, superhelical domain | 0 | DIRECT |
54292,47741
54292 - 2Fe-2S ferredoxin-like
47741 - CO dehydrogenase ISP C-domain like | 0 | DIRECT |
57196,63825
57196 - EGF/Laminin
63825 - YWTD domain | 0 | DIRECT |
53738,55957
53738 - Phosphoglucomutase, first 3 domains
55957 - Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
48403,52151
48403 - Ankyrin repeat
52151 - FabD/lysophospholipase-like | 0 | DIRECT |
81324,81327
81324 - Voltage-gated potassium channels
81327 - Small-conductance potassium channel | 0 | DIRECT |
55920,46785
55920 - Creatinase/aminopeptidase
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
81383,52047
81383 - F-box domain
52047 - RNI-like | 0 | DIRECT |
54495,46934
54495 - UBC-like
46934 - UBA-like | 0 | DIRECT |
47473,51695
47473 - EF-hand
51695 - PLC-like phosphodiesterases | 0 | DIRECT |
47220,47220
47220 - alpha-catenin/vinculin-like
47220 - alpha-catenin/vinculin-like | 0 | DIRECT |
48464,89009
48464 - ENTH/VHS domain
89009 - GAT-like domain | 0 | DIRECT |
141739,141739
141739 - MFPT repeat-like
141739 - MFPT repeat-like | 0 | DIRECT |
144232,82199
144232 - HIT/MYND zinc finger-like
82199 - SET domain | 0 | DIRECT |
55729,55729
55729 - Acyl-CoA N-acyltransferases (Nat)
55729 - Acyl-CoA N-acyltransferases (Nat) | 0 | DIRECT |
57903,51197
57903 - FYVE/PHD zinc finger
51197 - Clavaminate synthase-like | 0 | DIRECT |
54160,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
57414,57414
57414 - Hairpin loop containing domain-like
57414 - Hairpin loop containing domain-like | 0 | DIRECT |
52047,52047
52047 - RNI-like
52047 - RNI-like | 0 | DIRECT |
47090,55486
47090 - PGBD-like
55486 - Metalloproteases ("zincins"), catalytic domain | 0 | DIRECT |
47203,47203
47203 - Acyl-CoA dehydrogenase C-terminal domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
82919,53300
82919 - Zn-finger domain of Sec23/24
53300 - vWA-like | 0 | DIRECT |
50729,47473
50729 - PH domain-like
47473 - EF-hand | 0 | DIRECT |
47895,52540
47895 - Transducin (alpha subunit), insertion domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
48431,56968
48431 - Lipovitellin-phosvitin complex, superhelical domain
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | DIRECT |
103473,103473
103473 - MFS general substrate transporter
103473 - MFS general substrate transporter | 0 | DIRECT |
48371,48371
48371 - ARM repeat
48371 - ARM repeat | 0 | DIRECT |
54236,47031
54236 - Ubiquitin-like
47031 - Second domain of FERM | 0 | DIRECT |
52440,56059
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like | 0 | DIRECT |
47473,103506
47473 - EF-hand
103506 - Mitochondrial carrier | 0 | DIRECT |
55973,55973
55973 - S-adenosylmethionine synthetase
55973 - S-adenosylmethionine synthetase | 0 | DIRECT |
50692,54585
50692 - ADC-like
54585 - Cdc48 domain 2-like | 0 | DIRECT |
81631,55003
81631 - PAP/OAS1 substrate-binding domain
55003 - PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | DIRECT |
50156,50044
50156 - PDZ domain-like
50044 - SH3-domain | 0 | DIRECT |
55486,57552
55486 - Metalloproteases ("zincins"), catalytic domain
57552 - Blood coagulation inhibitor (disintegrin) | 0 | DIRECT |
47769,47769
47769 - SAM/Pointed domain
47769 - SAM/Pointed domain | 0 | DIRECT |
55326,56042
55326 - PurM N-terminal domain-like
56042 - PurM C-terminal domain-like | 0 | DIRECT |
56112,48371
56112 - Protein kinase-like (PK-like)
48371 - ARM repeat | 0 | DIRECT |
51556,51338
51556 - Metallo-dependent hydrolases
51338 - Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
50978,50998
50978 - WD40 repeat-like
50998 - Quinoprotein alcohol dehydrogenase-like | 0 | DIRECT |
47587,56399
47587 - Domain of poly(ADP-ribose) polymerase
56399 - ADP-ribosylation | 0 | DIRECT |
46785,46785
46785 - "Winged helix" DNA-binding domain
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
64593,74853
64593 - Intermediate filament protein, coiled coil region
74853 - Lamin A/C globular tail domain | 0 | DIRECT |
51905,56425
51905 - FAD/NAD(P)-binding domain
56425 - Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | DIRECT |
74788,75632
74788 - Cullin repeat-like
75632 - Cullin homology domain | 0 | DIRECT |
57889,57889
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0 | DIRECT |
51338,51556
51338 - Composite domain of metallo-dependent hydrolases
51556 - Metallo-dependent hydrolases | 0 | DIRECT |
47741,56176
47741 - CO dehydrogenase ISP C-domain like
56176 - FAD-binding/transporter-associated domain-like | 0 | DIRECT |
81301,81631
81301 - Nucleotidyltransferase
81631 - PAP/OAS1 substrate-binding domain | 0 | DIRECT |
52047,48371
52047 - RNI-like
48371 - ARM repeat | 0 | DIRECT |
52540,47917
52540 - P-loop containing nucleoside triphosphate hydrolases
47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
49493,49493
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
51695,49562
51695 - PLC-like phosphodiesterases
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
81324,53850
81324 - Voltage-gated potassium channels
53850 - Periplasmic binding protein-like II | 0 | DIRECT |
49348,55711
49348 - Clathrin adaptor appendage domain
55711 - Subdomain of clathrin and coatomer appendage domain | 0 | DIRECT |
100920,100934
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
54211,55060
54211 - Ribosomal protein S5 domain 2-like
55060 - GHMP Kinase, C-terminal domain | 0 | DIRECT |
52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.00244 | INHERITED FROM: sick || organism stress response variant || dauer lifespan variant || organism environmental stimulus response variant || organism UV hypersensitive || organism UV response variant || slow growth || dauer lifespan extended |
55550,56112
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0.01532 | INHERITED FROM: acetylcholinesterase inhibitor resistant || aldicarb resistant |
48452,48452
48452 - TPR-like
48452 - TPR-like | 0.1172 | INHERITED FROM: chemotaxis variant || organism environmental stimulus response variant || pattern of transgene expression variant || aqueous chemosensory response variant || dauer defective || gene expression variant || positive chemotaxis defective |
81660,56784
81660 - Metal cation-transporting ATPase, ATP-binding domain N
56784 - HAD-like | 0.1443 | INHERITED FROM: nicotine hypersensitive || organism environmental stimulus response variant || lipid composition variant |
56112,55073
56112 - Protein kinase-like (PK-like)
55073 - Nucleotide cyclase | 0.1443 | INHERITED FROM: AWC odorant chemotaxis defective || benzaldehyde chemotaxis variant || magnesium chemotaxis defective || iodide chemotaxis variant || chemotaxis variant || iodide chemotaxis defective || chemosensory response variant || AWC odorant chemotaxis variant || alkaline pH chemotaxis variant || anion positive chemotaxis variant || anion positive chemotaxis defective || organism environmental stimulus response variant || aqueous chemosensory response variant || chemical response variant || cation positive chemotaxis variant || bromide chemotaxis variant || cation positive chemotaxis defective || lithium chemotaxis defective || positive chemotaxis variant || bromide chemotaxis defective |
56436,56436
56436 - C-type lectin-like
56436 - C-type lectin-like | 0.1744 | INHERITED FROM: cadmium hypersensitive |
52540,50447
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins | 0.2182 | INHERITED FROM: mRNA levels reduced || mRNA levels increased || proteasome core activity variant || protein phosphorylation variant || protein modification variant || protein protein interaction variant || transgene expression variant || protein aggregation variant || protein phosphorylation increased |
56436,49854
56436 - C-type lectin-like
49854 - Spermadhesin, CUB domain | 0.2632 | INHERITED FROM: cadmium response variant || cadmium hypersensitive |
56784,81665
56784 - HAD-like
81665 - Calcium ATPase, transmembrane domain M | 0.2671 | INHERITED FROM: nicotine hypersensitive || organism environmental stimulus response variant |
51735,48179
51735 - NAD(P)-binding Rossmann-fold domains
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0.2671 | INHERITED FROM: fat content variant || lipid metabolism variant |
49785,49785
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like | 0.295 | INHERITED FROM: protein interaction variant || protein protein interaction variant || protein aggregation variant |
90123,52540
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.2965 | INHERITED FROM: RNAi response variant || organism environmental stimulus response variant || metal response variant || colchicine hypersensitive || cadmium response variant |
50978,50978
50978 - WD40 repeat-like
50978 - WD40 repeat-like | 0.3259 | INHERITED FROM: chemotaxis variant || aqueous positive chemotaxis defective || aqueous chemosensory response variant || dauer defective || osmotic avoidance variant || mechanosensation variant || aqueous positive chemotaxis variant || odorant chemosensory response variant || negative chemotaxis variant || positive chemotaxis variant || positive chemotaxis defective |
52833,52833
52833 - Thioredoxin-like
52833 - Thioredoxin-like | 0.3259 | INHERITED FROM: pattern of transgene expression variant || protein interaction variant || protein protein interaction variant || protein aggregation variant |
50156,50156
50156 - PDZ domain-like
50156 - PDZ domain-like | 0.3606 | INHERITED FROM: protein subcellular localization variant |
47473,47473
47473 - EF-hand
47473 - EF-hand | 0.3606 | INHERITED FROM: acetylcholinesterase inhibitor hypersensitive || acetylcholinesterase inhibitor response variant || aldicarb response variant |
54928,54928
54928 - RNA-binding domain, RBD
54928 - RNA-binding domain, RBD | 0.3817 | INHERITED FROM: organism starvation response variant || late larval arrest || gene expression variant || starvation induced apoptosis variant |
63712,90112
63712 - Nicotinic receptor ligand binding domain-like
90112 - Neurotransmitter-gated ion-channel transmembrane pore | 0.4078 | INHERITED FROM: nicotine resistant || selenium response variant || protein degradation variant || organism environmental stimulus response variant || hypoosmotic shock hypersensitive || ivermectin resistant || ivermectin response variant || slowing response on food variant || aqueous chemosensory response variant || chemical response variant || cholinergic agonist resistant || antihelmintic response variant || mechanosensation variant || sodium chloride chemotaxis variant || drug response variant || positive chemotaxis variant || DMPP response variant |
48403,48403
48403 - Ankyrin repeat
48403 - Ankyrin repeat | 0.4824 | INHERITED FROM: organism environmental stimulus response variant |
57716,57716
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0.4993 | INHERITED FROM: protein expression variant || organism metabolism processing variant || protein expression reduced |
52833,47616
52833 - Thioredoxin-like
47616 - GST C-terminal domain-like | 0.5213 | INHERITED FROM: enzyme activity reduced || organism stress response variant || organism environmental stimulus response variant || metal response variant || organism electrophilic stress hypersensitive || organism heat hypersensitive || paraquat response variant || cadmium response variant || cadmium hypersensitive || enzyme activity variant |
57716,48508
57716 - Glucocorticoid receptor-like (DNA-binding domain)
48508 - Nuclear receptor ligand-binding domain | 0.5461 | INHERITED FROM: dauer resistance to harsh conditions variant || chemical hypersensitive || transgene expression reduced || SDS sensitive dauer |
50044,55550
50044 - SH3-domain
55550 - SH2 domain | 0.5819 | INHERITED FROM: protein expression reduced |
63380,52343
63380 - Riboflavin synthase domain-like
52343 - Ferredoxin reductase-like, C-terminal NADP-linked domain | 0.6398 | INHERITED FROM: transgene subcellular localization variant |
51045,51045
51045 - WW domain
51045 - WW domain | 0.6398 | INHERITED FROM: transgene expression variant |
57424,57424
57424 - LDL receptor-like module
57424 - LDL receptor-like module | 0.6794 | INHERITED FROM: protein expression reduced |
51905,54373
51905 - FAD/NAD(P)-binding domain
54373 - FAD-linked reductases, C-terminal domain | 0.6794 | INHERITED FROM: shortened life span || life span variant |
50249,55681
50249 - Nucleic acid-binding proteins
55681 - Class II aaRS and biotin synthetases | 0.7038 | INHERITED FROM: transgene expression increased |
57903,57903
57903 - FYVE/PHD zinc finger
57903 - FYVE/PHD zinc finger | 0.7038 | INHERITED FROM: organism environmental stimulus response variant || organism UV hypersensitive || organism UV response variant |
57196,57196
57196 - EGF/Laminin
57196 - EGF/Laminin | 0.7487 | INHERITED FROM: metabolic pathway variant || growth rate variant || protein expression reduced |
55550,50044
55550 - SH2 domain
50044 - SH3-domain | 0.7719 | INHERITED FROM: level of protein expression variant || protein expression variant || protein expression reduced |
48726,49265
48726 - Immunoglobulin
49265 - Fibronectin type III | 0.8549 | INHERITED FROM: protein degradation variant || chemical response variant || aldicarb resistant || growth rate variant |
48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin | 0.9018 | INHERITED FROM: protein degradation variant || growth rate variant |
54211,55666
54211 - Ribosomal protein S5 domain 2-like
55666 - Ribonuclease PH domain 2-like | 0.9537 | INHERITED FROM: early larval arrest |
49562,49562
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0.9622 | INHERITED FROM: drug resistant |
53300,56436
53300 - vWA-like
56436 - C-type lectin-like | 1 | INHERITED FROM: pathogen susceptibility increased || pathogen induced death increased |
57850,57845
57850 - RING/U-box
57845 - B-box zinc-binding domain | 1 | INHERITED FROM: transgene subcellular localization variant || protein interaction variant || protein protein interaction variant || transgene expression variant || protein aggregation variant |
57850,57850
57850 - RING/U-box
57850 - RING/U-box | 1 | INHERITED FROM: transgene subcellular localization variant || protein interaction variant || protein protein interaction variant || protein aggregation variant |
52777,52777
52777 - CoA-dependent acyltransferases
52777 - CoA-dependent acyltransferases | 1 | INHERITED FROM: fat content variant || lipid metabolism variant |
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
48425,50729
48425 - Sec7 domain
50729 - PH domain-like | 0 | Direct |
53474,53474
53474 - alpha/beta-Hydrolases
53474 - alpha/beta-Hydrolases | 0 | Direct |
48592,54849
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like | 0 | Direct |
82615,82615
82615 - Polo-box domain
82615 - Polo-box domain | 0 | Direct |
48371,56112
48371 - ARM repeat
56112 - Protein kinase-like (PK-like) | 0 | Direct |
57184,57184
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | Direct |
82895,82895
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat | 0 | Direct |
57184,57196
57184 - Growth factor receptor domain
57196 - EGF/Laminin | 0 | Direct |
47954,47954
47954 - Cyclin-like
47954 - Cyclin-like | 0 | Direct |
49742,49742
49742 - PHM/PNGase F
49742 - PHM/PNGase F | 0 | Direct |
161111,160240
161111 - Cation efflux protein transmembrane domain-like
160240 - Cation efflux protein cytoplasmic domain-like | 0 | Direct |
51735,55347
51735 - NAD(P)-binding Rossmann-fold domains
55347 - Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | Direct |
50249,50249
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins | 0 | Direct |
50677,52374
50677 - ValRS/IleRS/LeuRS editing domain
52374 - Nucleotidylyl transferase | 0 | Direct |
56059,52210
56059 - Glutathione synthetase ATP-binding domain-like
52210 - Succinyl-CoA synthetase domains | 0 | Direct |
57196,57184
57196 - EGF/Laminin
57184 - Growth factor receptor domain | 0 | Direct |
74650,51445
74650 - Galactose mutarotase-like
51445 - (Trans)glycosidases | 0 | Direct |
54849,52029
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0 | Direct |
54695,81382
54695 - POZ domain
81382 - Skp1 dimerisation domain-like | 0 | Direct |
55681,52954
55681 - Class II aaRS and biotin synthetases
52954 - Class II aaRS ABD-related | 0 | Direct |
53187,49464
53187 - Zn-dependent exopeptidases
49464 - Carboxypeptidase regulatory domain-like | 0 | Direct |
57625,57625
57625 - Invertebrate chitin-binding proteins
57625 - Invertebrate chitin-binding proteins | 0 | Direct |
54534,54534
54534 - FKBP-like
54534 - FKBP-like | 0 | Direct |
50447,50465
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
57756,50630
57756 - Retrovirus zinc finger-like domains
50630 - Acid proteases | 0 | Direct |
53901,53901
53901 - Thiolase-like
53901 - Thiolase-like | 0 | Direct |
57889,48350
57889 - Cysteine-rich domain
48350 - GTPase activation domain, GAP | 0 | Direct |
49265,48726
49265 - Fibronectin type III
48726 - Immunoglobulin | 0 | Direct |
53187,55031
53187 - Zn-dependent exopeptidases
55031 - Bacterial exopeptidase dimerisation domain | 0 | Direct |
51905,55424
51905 - FAD/NAD(P)-binding domain
55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | Direct |
57535,57535
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | Direct |
81698,81698
81698 - FF domain
81698 - FF domain | 0 | Direct |
68923,53795
68923 - PEP carboxykinase N-terminal domain
53795 - PEP carboxykinase-like | 0 | Direct |
50729,56112
50729 - PH domain-like
56112 - Protein kinase-like (PK-like) | 0 | Direct |
51735,50129
51735 - NAD(P)-binding Rossmann-fold domains
50129 - GroES-like | 0 | Direct |
57889,50729
57889 - Cysteine-rich domain
50729 - PH domain-like | 0 | Direct |
49313,49313
49313 - Cadherin-like
49313 - Cadherin-like | 0 | Direct |
53738,53738
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains | 0 | Direct |
54160,54160
54160 - Chromo domain-like
54160 - Chromo domain-like | 0 | Direct |
75632,46785
75632 - Cullin homology domain
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
53067,100920
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
57362,57362
57362 - BPTI-like
57362 - BPTI-like | 0 | Direct |
51445,51445
51445 - (Trans)glycosidases
51445 - (Trans)glycosidases | 0 | Direct |
51445,54556
51445 - (Trans)glycosidases
54556 - Chitinase insertion domain | 0 | Direct |
54768,54768
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like | 0 | Direct |
48065,50729
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like | 0 | Direct |
52518,52922
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52922 - TK C-terminal domain-like | 0 | Direct |
88713,88688
88713 - Glycoside hydrolase/deacetylase
88688 - Families 57/38 glycoside transferase middle domain | 0 | Direct |
56645,47203
56645 - Acyl-CoA dehydrogenase NM domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
52518,52518
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52518 - Thiamin diphosphate-binding fold (THDP-binding) | 0 | Direct |
47576,47576
47576 - Calponin-homology domain, CH-domain
47576 - Calponin-homology domain, CH-domain | 0 | Direct |
50129,51735
50129 - GroES-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | Direct |
55785,55785
55785 - PYP-like sensor domain (PAS domain)
55785 - PYP-like sensor domain (PAS domain) | 0 | Direct |
49562,48371
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat | 0 | Direct |
161093,161093
161093 - MgtE membrane domain-like
161093 - MgtE membrane domain-like | 0 | Direct |
81383,50978
81383 - F-box domain
50978 - WD40 repeat-like | 0 | Direct |
52540,140990
52540 - P-loop containing nucleoside triphosphate hydrolases
140990 - FtsH protease domain-like | 0 | Direct |
141673,50800
141673 - MOSC N-terminal domain-like
50800 - PK beta-barrel domain-like | 0 | Direct |
57850,117839
57850 - RING/U-box
117839 - WWE domain | 0 | Direct |
56059,51246
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 0 | Direct |
46966,46966
46966 - Spectrin repeat
46966 - Spectrin repeat | 0 | Direct |
47031,50729
47031 - Second domain of FERM
50729 - PH domain-like | 0 | Direct |
55874,54211
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
54211 - Ribosomal protein S5 domain 2-like | 0 | Direct |
52540,81271
52540 - P-loop containing nucleoside triphosphate hydrolases
81271 - TGS-like | 0 | Direct |
52283,51735
52283 - Formate/glycerate dehydrogenase catalytic domain-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | Direct |
47413,46689
47413 - lambda repressor-like DNA-binding domains
46689 - Homeodomain-like | 0 | Direct |
51206,51206
51206 - cAMP-binding domain-like
51206 - cAMP-binding domain-like | 0 | Direct |
54665,56003
54665 - CO dehydrogenase molybdoprotein N-domain-like
56003 - Molybdenum cofactor-binding domain | 0 | Direct |
57903,82199
57903 - FYVE/PHD zinc finger
82199 - SET domain | 0 | Direct |
64356,49447
64356 - SNARE-like
49447 - Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
50044,50044
50044 - SH3-domain
50044 - SH3-domain | 0 | Direct |
57938,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
101690,53098
101690 - PAZ domain
53098 - Ribonuclease H-like | 0 | Direct |
54897,53187
54897 - Protease propeptides/inhibitors
53187 - Zn-dependent exopeptidases | 0 | Direct |
52540,90123
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region | 0 | Direct |
57196,49899
57196 - EGF/Laminin
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
52490,55307
52490 - Tubulin nucleotide-binding domain-like
55307 - Tubulin C-terminal domain-like | 0 | Direct |
50044,52540
50044 - SH3-domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
54585,52540
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
52374,47323
52374 - Nucleotidylyl transferase
47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
57863,48403
57863 - ArfGap/RecO-like zinc finger
48403 - Ankyrin repeat | 0 | Direct |
53067,53067
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 0 | Direct |
51971,54373
51971 - Nucleotide-binding domain
54373 - FAD-linked reductases, C-terminal domain | 0 | Direct |
57756,57756
57756 - Retrovirus zinc finger-like domains
57756 - Retrovirus zinc finger-like domains | 0 | Direct |
54001,49758
54001 - Cysteine proteinases
49758 - Calpain large subunit, middle domain (domain III) | 0 | Direct |
52540,46785
52540 - P-loop containing nucleoside triphosphate hydrolases
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
56601,48403
56601 - beta-lactamase/transpeptidase-like
48403 - Ankyrin repeat | 0 | Direct |
46938,52087
46938 - CRAL/TRIO N-terminal domain
52087 - CRAL/TRIO domain | 0 | Direct |
81324,81296
81324 - Voltage-gated potassium channels
81296 - E set domains | 0 | Direct |
55394,55394
55394 - Bactericidal permeability-increasing protein, BPI
55394 - Bactericidal permeability-increasing protein, BPI | 0 | Direct |
51735,56327
51735 - NAD(P)-binding Rossmann-fold domains
56327 - LDH C-terminal domain-like | 0 | Direct |
48179,48179
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | Direct |
56091,50249
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins | 0 | Direct |
56112,82615
56112 - Protein kinase-like (PK-like)
82615 - Polo-box domain | 0 | Direct |
90229,90229
90229 - CCCH zinc finger
90229 - CCCH zinc finger | 0 | Direct |
52743,49785
52743 - Subtilisin-like
49785 - Galactose-binding domain-like | 0 | Direct |
81811,82754
81811 - Helical domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
52113,52113
52113 - BRCT domain
52113 - BRCT domain | 0 | Direct |
56672,100879
56672 - DNA/RNA polymerases
100879 - Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
54236,54236
54236 - Ubiquitin-like
54236 - Ubiquitin-like | 0 | Direct |
48334,52540
48334 - DNA repair protein MutS, domain III
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
54897,52743
54897 - Protease propeptides/inhibitors
52743 - Subtilisin-like | 0 | Direct |
55486,50923
55486 - Metalloproteases ("zincins"), catalytic domain
50923 - Hemopexin-like domain | 0 | Direct |
51445,51011
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain | 0 | Direct |
81333,81333
81333 - F1F0 ATP synthase subunit C
81333 - F1F0 ATP synthase subunit C | 0 | Direct |
56968,48431
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
48431 - Lipovitellin-phosvitin complex, superhelical domain | 0 | Direct |
54292,47741
54292 - 2Fe-2S ferredoxin-like
47741 - CO dehydrogenase ISP C-domain like | 0 | Direct |
57196,63825
57196 - EGF/Laminin
63825 - YWTD domain | 0 | Direct |
53738,55957
53738 - Phosphoglucomutase, first 3 domains
55957 - Phosphoglucomutase, C-terminal domain | 0 | Direct |
48403,52151
48403 - Ankyrin repeat
52151 - FabD/lysophospholipase-like | 0 | Direct |
81324,81327
81324 - Voltage-gated potassium channels
81327 - Small-conductance potassium channel | 0 | Direct |
55920,46785
55920 - Creatinase/aminopeptidase
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
81383,52047
81383 - F-box domain
52047 - RNI-like | 0 | Direct |
54495,46934
54495 - UBC-like
46934 - UBA-like | 0 | Direct |
47473,51695
47473 - EF-hand
51695 - PLC-like phosphodiesterases | 0 | Direct |
47220,47220
47220 - alpha-catenin/vinculin-like
47220 - alpha-catenin/vinculin-like | 0 | Direct |
48464,89009
48464 - ENTH/VHS domain
89009 - GAT-like domain | 0 | Direct |
141739,141739
141739 - MFPT repeat-like
141739 - MFPT repeat-like | 0 | Direct |
144232,82199
144232 - HIT/MYND zinc finger-like
82199 - SET domain | 0 | Direct |
55729,55729
55729 - Acyl-CoA N-acyltransferases (Nat)
55729 - Acyl-CoA N-acyltransferases (Nat) | 0 | Direct |
57903,51197
57903 - FYVE/PHD zinc finger
51197 - Clavaminate synthase-like | 0 | Direct |
54160,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
57414,57414
57414 - Hairpin loop containing domain-like
57414 - Hairpin loop containing domain-like | 0 | Direct |
52047,52047
52047 - RNI-like
52047 - RNI-like | 0 | Direct |
47090,55486
47090 - PGBD-like
55486 - Metalloproteases ("zincins"), catalytic domain | 0 | Direct |
47203,47203
47203 - Acyl-CoA dehydrogenase C-terminal domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
82919,53300
82919 - Zn-finger domain of Sec23/24
53300 - vWA-like | 0 | Direct |
50729,47473
50729 - PH domain-like
47473 - EF-hand | 0 | Direct |
47895,52540
47895 - Transducin (alpha subunit), insertion domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
48431,56968
48431 - Lipovitellin-phosvitin complex, superhelical domain
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | Direct |
103473,103473
103473 - MFS general substrate transporter
103473 - MFS general substrate transporter | 0 | Direct |
48371,48371
48371 - ARM repeat
48371 - ARM repeat | 0 | Direct |
54236,47031
54236 - Ubiquitin-like
47031 - Second domain of FERM | 0 | Direct |
52440,56059
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like | 0 | Direct |
47473,103506
47473 - EF-hand
103506 - Mitochondrial carrier | 0 | Direct |
55973,55973
55973 - S-adenosylmethionine synthetase
55973 - S-adenosylmethionine synthetase | 0 | Direct |
50692,54585
50692 - ADC-like
54585 - Cdc48 domain 2-like | 0 | Direct |
81631,55003
81631 - PAP/OAS1 substrate-binding domain
55003 - PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | Direct |
50156,50044
50156 - PDZ domain-like
50044 - SH3-domain | 0 | Direct |
55486,57552
55486 - Metalloproteases ("zincins"), catalytic domain
57552 - Blood coagulation inhibitor (disintegrin) | 0 | Direct |
47769,47769
47769 - SAM/Pointed domain
47769 - SAM/Pointed domain | 0 | Direct |
55326,56042
55326 - PurM N-terminal domain-like
56042 - PurM C-terminal domain-like | 0 | Direct |
56112,48371
56112 - Protein kinase-like (PK-like)
48371 - ARM repeat | 0 | Direct |
51556,51338
51556 - Metallo-dependent hydrolases
51338 - Composite domain of metallo-dependent hydrolases | 0 | Direct |
50978,50998
50978 - WD40 repeat-like
50998 - Quinoprotein alcohol dehydrogenase-like | 0 | Direct |
47587,56399
47587 - Domain of poly(ADP-ribose) polymerase
56399 - ADP-ribosylation | 0 | Direct |
46785,46785
46785 - "Winged helix" DNA-binding domain
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
64593,74853
64593 - Intermediate filament protein, coiled coil region
74853 - Lamin A/C globular tail domain | 0 | Direct |
51905,56425
51905 - FAD/NAD(P)-binding domain
56425 - Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | Direct |
74788,75632
74788 - Cullin repeat-like
75632 - Cullin homology domain | 0 | Direct |
57889,57889
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0 | Direct |
51338,51556
51338 - Composite domain of metallo-dependent hydrolases
51556 - Metallo-dependent hydrolases | 0 | Direct |
47741,56176
47741 - CO dehydrogenase ISP C-domain like
56176 - FAD-binding/transporter-associated domain-like | 0 | Direct |
81301,81631
81301 - Nucleotidyltransferase
81631 - PAP/OAS1 substrate-binding domain | 0 | Direct |
52047,48371
52047 - RNI-like
48371 - ARM repeat | 0 | Direct |
52540,47917
52540 - P-loop containing nucleoside triphosphate hydrolases
47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
49493,49493
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
51695,49562
51695 - PLC-like phosphodiesterases
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
81324,53850
81324 - Voltage-gated potassium channels
53850 - Periplasmic binding protein-like II | 0 | Direct |
49348,55711
49348 - Clathrin adaptor appendage domain
55711 - Subdomain of clathrin and coatomer appendage domain | 0 | Direct |
100920,100934
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
54211,55060
54211 - Ribosomal protein S5 domain 2-like
55060 - GHMP Kinase, C-terminal domain | 0 | Direct |
52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.00244 | Inherited |
55550,56112
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0.01532 | Inherited |
48452,48452
48452 - TPR-like
48452 - TPR-like | 0.1172 | Inherited |
81660,56784
81660 - Metal cation-transporting ATPase, ATP-binding domain N
56784 - HAD-like | 0.1443 | Inherited |
56112,55073
56112 - Protein kinase-like (PK-like)
55073 - Nucleotide cyclase | 0.1443 | Inherited |
56436,56436
56436 - C-type lectin-like
56436 - C-type lectin-like | 0.1744 | Inherited |
52540,50447
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins | 0.2182 | Inherited |
56436,49854
56436 - C-type lectin-like
49854 - Spermadhesin, CUB domain | 0.2632 | Inherited |
56784,81665
56784 - HAD-like
81665 - Calcium ATPase, transmembrane domain M | 0.2671 | Inherited |
51735,48179
51735 - NAD(P)-binding Rossmann-fold domains
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0.2671 | Inherited |
49785,49785
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like | 0.295 | Inherited |
90123,52540
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.2965 | Inherited |
50978,50978
50978 - WD40 repeat-like
50978 - WD40 repeat-like | 0.3259 | Inherited |
52833,52833
52833 - Thioredoxin-like
52833 - Thioredoxin-like | 0.3259 | Inherited |
50156,50156
50156 - PDZ domain-like
50156 - PDZ domain-like | 0.3606 | Inherited |
47473,47473
47473 - EF-hand
47473 - EF-hand | 0.3606 | Inherited |
54928,54928
54928 - RNA-binding domain, RBD
54928 - RNA-binding domain, RBD | 0.3817 | Inherited |
63712,90112
63712 - Nicotinic receptor ligand binding domain-like
90112 - Neurotransmitter-gated ion-channel transmembrane pore | 0.4078 | Inherited |
48403,48403
48403 - Ankyrin repeat
48403 - Ankyrin repeat | 0.4824 | Inherited |
57716,57716
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0.4993 | Inherited |
52833,47616
52833 - Thioredoxin-like
47616 - GST C-terminal domain-like | 0.5213 | Inherited |
57716,48508
57716 - Glucocorticoid receptor-like (DNA-binding domain)
48508 - Nuclear receptor ligand-binding domain | 0.5461 | Inherited |
50044,55550
50044 - SH3-domain
55550 - SH2 domain | 0.5819 | Inherited |
63380,52343
63380 - Riboflavin synthase domain-like
52343 - Ferredoxin reductase-like, C-terminal NADP-linked domain | 0.6398 | Inherited |
51045,51045
51045 - WW domain
51045 - WW domain | 0.6398 | Inherited |
57424,57424
57424 - LDL receptor-like module
57424 - LDL receptor-like module | 0.6794 | Inherited |
51905,54373
51905 - FAD/NAD(P)-binding domain
54373 - FAD-linked reductases, C-terminal domain | 0.6794 | Inherited |
50249,55681
50249 - Nucleic acid-binding proteins
55681 - Class II aaRS and biotin synthetases | 0.7038 | Inherited |
57903,57903
57903 - FYVE/PHD zinc finger
57903 - FYVE/PHD zinc finger | 0.7038 | Inherited |
57196,57196
57196 - EGF/Laminin
57196 - EGF/Laminin | 0.7487 | Inherited |
55550,50044
55550 - SH2 domain
50044 - SH3-domain | 0.7719 | Inherited |
48726,49265
48726 - Immunoglobulin
49265 - Fibronectin type III | 0.8549 | Inherited |
48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin | 0.9018 | Inherited |
54211,55666
54211 - Ribosomal protein S5 domain 2-like
55666 - Ribonuclease PH domain 2-like | 0.9537 | Inherited |
49562,49562
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0.9622 | Inherited |
53300,56436
53300 - vWA-like
56436 - C-type lectin-like | 1 | Inherited |
57850,57845
57850 - RING/U-box
57845 - B-box zinc-binding domain | 1 | Inherited |
57850,57850
57850 - RING/U-box
57850 - RING/U-box | 1 | Inherited |
52777,52777
52777 - CoA-dependent acyltransferases
52777 - CoA-dependent acyltransferases | 1 | Inherited |
(show details)
Supra-domains annotated to this WP term (Not in SPWP)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
48371,48371,48371
48371 - ARM repeat
48371 - ARM repeat
48371 - ARM repeat | 0 | DIRECT |
56112,82615,82615
56112 - Protein kinase-like (PK-like)
82615 - Polo-box domain
82615 - Polo-box domain | 0 | DIRECT |
54585,52540,52540
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
56645,47203,47203
56645 - Acyl-CoA dehydrogenase NM domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
57414,57414,57414
57414 - Hairpin loop containing domain-like
57414 - Hairpin loop containing domain-like
57414 - Hairpin loop containing domain-like | 0 | DIRECT |
81301,81631,55003
81301 - Nucleotidyltransferase
81631 - PAP/OAS1 substrate-binding domain
55003 - PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | DIRECT |
53067,100920,100934
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
49899,49899,49899
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
48726,49265,48726
48726 - Immunoglobulin
49265 - Fibronectin type III
48726 - Immunoglobulin | 0 | DIRECT |
46938,52087,101576
46938 - CRAL/TRIO N-terminal domain
52087 - CRAL/TRIO domain
101576 - Supernatant protein factor (SPF), C-terminal domain | 0 | DIRECT |
57362,57362,57362
57362 - BPTI-like
57362 - BPTI-like
57362 - BPTI-like | 0 | DIRECT |
46966,46966,46966
46966 - Spectrin repeat
46966 - Spectrin repeat
46966 - Spectrin repeat | 0 | DIRECT |
50692,54585,52540
50692 - ADC-like
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
47090,55486,50923
47090 - PGBD-like
55486 - Metalloproteases ("zincins"), catalytic domain
50923 - Hemopexin-like domain | 0 | DIRECT |
50044,55550,56112
50044 - SH3-domain
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
50729,47473,51695
50729 - PH domain-like
47473 - EF-hand
51695 - PLC-like phosphodiesterases | 0 | DIRECT |
51735,48179,48179
51735 - NAD(P)-binding Rossmann-fold domains
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | DIRECT |
81296,81296,81296
81296 - E set domains
81296 - E set domains
81296 - E set domains | 0 | DIRECT |
49313,49313,49313
49313 - Cadherin-like
49313 - Cadherin-like
49313 - Cadherin-like | 0 | DIRECT |
52540,52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
50044,50044,50044
50044 - SH3-domain
50044 - SH3-domain
50044 - SH3-domain | 0 | DIRECT |
52540,50447,50465
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
49562,48371,56112
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
56436,49854,49854
56436 - C-type lectin-like
49854 - Spermadhesin, CUB domain
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
48452,48452,48452
48452 - TPR-like
48452 - TPR-like
48452 - TPR-like | 0 | DIRECT |
50129,51735,50129
50129 - GroES-like
51735 - NAD(P)-binding Rossmann-fold domains
50129 - GroES-like | 0 | DIRECT |
57567,57567,57567
57567 - Serine protease inhibitors
57567 - Serine protease inhibitors
57567 - Serine protease inhibitors | 0 | DIRECT |
54160,52540,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
82895,82895,82895
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat | 0 | DIRECT |
54292,47741,56176
54292 - 2Fe-2S ferredoxin-like
47741 - CO dehydrogenase ISP C-domain like
56176 - FAD-binding/transporter-associated domain-like | 0 | DIRECT |
63411,63411,63411
63411 - LuxS/MPP-like metallohydrolase
63411 - LuxS/MPP-like metallohydrolase
63411 - LuxS/MPP-like metallohydrolase | 0 | DIRECT |
52540,90123,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
54160,54160,52540
54160 - Chromo domain-like
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
74788,75632,46785
74788 - Cullin repeat-like
75632 - Cullin homology domain
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
74650,51445,51011
74650 - Galactose mutarotase-like
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain | 0 | DIRECT |
90123,52540,90123
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region | 0 | DIRECT |
53738,53738,53738
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains | 0 | DIRECT |
54928,54928,54928
54928 - RNA-binding domain, RBD
54928 - RNA-binding domain, RBD
54928 - RNA-binding domain, RBD | 0 | DIRECT |
49785,49785,49785
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like | 0 | DIRECT |
57938,49493,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
53738,53738,55957
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains
55957 - Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
54236,47031,50729
54236 - Ubiquitin-like
47031 - Second domain of FERM
50729 - PH domain-like | 0 | DIRECT |
50249,50249,50249
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
57535,57535,57535
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | DIRECT |
54897,52743,49785
54897 - Protease propeptides/inhibitors
52743 - Subtilisin-like
49785 - Galactose-binding domain-like | 0 | DIRECT |
53067,53067,100920
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
48592,54849,52029
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0 | DIRECT |
56968,48431,56968
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
48431 - Lipovitellin-phosvitin complex, superhelical domain
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | DIRECT |
52440,56059,51246
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 0 | DIRECT |
50156,50044,52540
50156 - PDZ domain-like
50044 - SH3-domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
57625,57625,57625
57625 - Invertebrate chitin-binding proteins
57625 - Invertebrate chitin-binding proteins
57625 - Invertebrate chitin-binding proteins | 0 | DIRECT |
55973,55973,55973
55973 - S-adenosylmethionine synthetase
55973 - S-adenosylmethionine synthetase
55973 - S-adenosylmethionine synthetase | 0 | DIRECT |
81660,56784,81665
81660 - Metal cation-transporting ATPase, ATP-binding domain N
56784 - HAD-like
81665 - Calcium ATPase, transmembrane domain M | 0.1603 | INHERITED FROM: nicotine hypersensitive || organism environmental stimulus response variant || lipid composition variant |
57424,57424,57424
57424 - LDL receptor-like module
57424 - LDL receptor-like module
57424 - LDL receptor-like module | 0.3974 | INHERITED FROM: level of protein expression variant || protein metabolism variant || protein expression reduced |
52833,52833,52833
52833 - Thioredoxin-like
52833 - Thioredoxin-like
52833 - Thioredoxin-like | 0.3974 | INHERITED FROM: pattern of transgene expression variant || protein interaction variant || protein protein interaction variant || protein aggregation variant |
56436,56436,49854
56436 - C-type lectin-like
56436 - C-type lectin-like
49854 - Spermadhesin, CUB domain | 0.4083 | INHERITED FROM: metal response variant || cadmium response variant || cadmium hypersensitive |
57716,57716,57716
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0.4824 | INHERITED FROM: protein degradation variant || level of protein expression variant || protein metabolism variant || protein expression variant || organism metabolism processing variant || protein expression reduced |
57850,57850,57850
57850 - RING/U-box
57850 - RING/U-box
57850 - RING/U-box | 0.8793 | INHERITED FROM: transgene subcellular localization variant || pattern of transgene expression variant || protein interaction variant || protein protein interaction variant || protein aggregation variant |
48726,48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin
48726 - Immunoglobulin | 0.9877 | INHERITED FROM: protein degradation variant || growth rate variant |
48726,48726,49265
48726 - Immunoglobulin
48726 - Immunoglobulin
49265 - Fibronectin type III | 1 | INHERITED FROM: protein degradation variant || growth rate variant |
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
48371,48371,48371
48371 - ARM repeat
48371 - ARM repeat
48371 - ARM repeat | 0 | Direct |
56112,82615,82615
56112 - Protein kinase-like (PK-like)
82615 - Polo-box domain
82615 - Polo-box domain | 0 | Direct |
54585,52540,52540
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
56645,47203,47203
56645 - Acyl-CoA dehydrogenase NM domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
57414,57414,57414
57414 - Hairpin loop containing domain-like
57414 - Hairpin loop containing domain-like
57414 - Hairpin loop containing domain-like | 0 | Direct |
81301,81631,55003
81301 - Nucleotidyltransferase
81631 - PAP/OAS1 substrate-binding domain
55003 - PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | Direct |
53067,100920,100934
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
49899,49899,49899
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
48726,49265,48726
48726 - Immunoglobulin
49265 - Fibronectin type III
48726 - Immunoglobulin | 0 | Direct |
46938,52087,101576
46938 - CRAL/TRIO N-terminal domain
52087 - CRAL/TRIO domain
101576 - Supernatant protein factor (SPF), C-terminal domain | 0 | Direct |
57362,57362,57362
57362 - BPTI-like
57362 - BPTI-like
57362 - BPTI-like | 0 | Direct |
46966,46966,46966
46966 - Spectrin repeat
46966 - Spectrin repeat
46966 - Spectrin repeat | 0 | Direct |
50692,54585,52540
50692 - ADC-like
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
47090,55486,50923
47090 - PGBD-like
55486 - Metalloproteases ("zincins"), catalytic domain
50923 - Hemopexin-like domain | 0 | Direct |
50044,55550,56112
50044 - SH3-domain
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0 | Direct |
50729,47473,51695
50729 - PH domain-like
47473 - EF-hand
51695 - PLC-like phosphodiesterases | 0 | Direct |
51735,48179,48179
51735 - NAD(P)-binding Rossmann-fold domains
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | Direct |
81296,81296,81296
81296 - E set domains
81296 - E set domains
81296 - E set domains | 0 | Direct |
49313,49313,49313
49313 - Cadherin-like
49313 - Cadherin-like
49313 - Cadherin-like | 0 | Direct |
52540,52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
50044,50044,50044
50044 - SH3-domain
50044 - SH3-domain
50044 - SH3-domain | 0 | Direct |
52540,50447,50465
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
49562,48371,56112
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat
56112 - Protein kinase-like (PK-like) | 0 | Direct |
56436,49854,49854
56436 - C-type lectin-like
49854 - Spermadhesin, CUB domain
49854 - Spermadhesin, CUB domain | 0 | Direct |
48452,48452,48452
48452 - TPR-like
48452 - TPR-like
48452 - TPR-like | 0 | Direct |
50129,51735,50129
50129 - GroES-like
51735 - NAD(P)-binding Rossmann-fold domains
50129 - GroES-like | 0 | Direct |
57567,57567,57567
57567 - Serine protease inhibitors
57567 - Serine protease inhibitors
57567 - Serine protease inhibitors | 0 | Direct |
54160,52540,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
82895,82895,82895
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat | 0 | Direct |
54292,47741,56176
54292 - 2Fe-2S ferredoxin-like
47741 - CO dehydrogenase ISP C-domain like
56176 - FAD-binding/transporter-associated domain-like | 0 | Direct |
63411,63411,63411
63411 - LuxS/MPP-like metallohydrolase
63411 - LuxS/MPP-like metallohydrolase
63411 - LuxS/MPP-like metallohydrolase | 0 | Direct |
52540,90123,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
54160,54160,52540
54160 - Chromo domain-like
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
74788,75632,46785
74788 - Cullin repeat-like
75632 - Cullin homology domain
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
74650,51445,51011
74650 - Galactose mutarotase-like
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain | 0 | Direct |
90123,52540,90123
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region | 0 | Direct |
53738,53738,53738
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains | 0 | Direct |
54928,54928,54928
54928 - RNA-binding domain, RBD
54928 - RNA-binding domain, RBD
54928 - RNA-binding domain, RBD | 0 | Direct |
49785,49785,49785
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like | 0 | Direct |
57938,49493,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
53738,53738,55957
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains
55957 - Phosphoglucomutase, C-terminal domain | 0 | Direct |
54236,47031,50729
54236 - Ubiquitin-like
47031 - Second domain of FERM
50729 - PH domain-like | 0 | Direct |
50249,50249,50249
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins | 0 | Direct |
57535,57535,57535
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | Direct |
54897,52743,49785
54897 - Protease propeptides/inhibitors
52743 - Subtilisin-like
49785 - Galactose-binding domain-like | 0 | Direct |
53067,53067,100920
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
48592,54849,52029
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0 | Direct |
56968,48431,56968
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
48431 - Lipovitellin-phosvitin complex, superhelical domain
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | Direct |
52440,56059,51246
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 0 | Direct |
50156,50044,52540
50156 - PDZ domain-like
50044 - SH3-domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
57625,57625,57625
57625 - Invertebrate chitin-binding proteins
57625 - Invertebrate chitin-binding proteins
57625 - Invertebrate chitin-binding proteins | 0 | Direct |
55973,55973,55973
55973 - S-adenosylmethionine synthetase
55973 - S-adenosylmethionine synthetase
55973 - S-adenosylmethionine synthetase | 0 | Direct |
81660,56784,81665
81660 - Metal cation-transporting ATPase, ATP-binding domain N
56784 - HAD-like
81665 - Calcium ATPase, transmembrane domain M | 0.1603 | Inherited |
57424,57424,57424
57424 - LDL receptor-like module
57424 - LDL receptor-like module
57424 - LDL receptor-like module | 0.3974 | Inherited |
52833,52833,52833
52833 - Thioredoxin-like
52833 - Thioredoxin-like
52833 - Thioredoxin-like | 0.3974 | Inherited |
56436,56436,49854
56436 - C-type lectin-like
56436 - C-type lectin-like
49854 - Spermadhesin, CUB domain | 0.4083 | Inherited |
57716,57716,57716
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0.4824 | Inherited |
57850,57850,57850
57850 - RING/U-box
57850 - RING/U-box
57850 - RING/U-box | 0.8793 | Inherited |
48726,48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin
48726 - Immunoglobulin | 0.9877 | Inherited |
48726,48726,49265
48726 - Immunoglobulin
48726 - Immunoglobulin
49265 - Fibronectin type III | 1 | Inherited |
Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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Trees by TreeVector
A presence/absence matrix is generated using protein domains and supradomains
for all genomes in SUPERFAMILY. The RAxML
software is used to produce a single, large tree topology using
heuristic parsimony methods. Genome combinations, or specific clades, can be displayed as
if individual trees had been produced. However, this data is extracted from the single
large tree. This produces a higher quality topology than if the trees had been produced
on their own, and allows the trees to be displayed instantly.
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