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Worm Phenotype (WP): organism physiology variant
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Phenotype Ontology
Like Gene Ontology (GO), phenotypy ontology classifies and organizes gene-mutant/null phenotypic information from the very general at the top to more specific terms in the directed acyclic graph (DAG) by viewing an individual term as a node and its relations to parental terms (allowing for multiple parents) as directed edges. To navigate this hierarchy, we display all parental phenotypic terms to the current phenotypic term of interest ordered by their shortest distances to the current term. Also, only direct children phenotypic terms of the current phenotypic term are listed. Phenotype ontologies we have incorporated are as follows:
- Disease Ontology (DO) Ontology (DO) DO semantically integrates disease and medical vocabularies through extensive cross mapping of DO terms to MeSH, ICD, NCI thesaurus, SNOMED and OMIM.
- Human Phenotype (HP) Ontology (HP) HP captures phenotypic abnormalities that are described in OMIM, along with the corresponding disease-causing genes. It includes three complementary biological concepts: Mode_of_Inheritance (MI), ONset_and_clinical_course (ON), and Phenotypic_Abnormality (PA).
- Mouse Phenotype (MP) Ontology (MP) MP describes phenotypes of the mouse after a specific gene is genetically disrupted. Using it, Mouse Genome Informatics (MGI) provides high-coverate gene-level phenotypes for the mouse.
- Worm Phenotype (WP) Ontology (WP) WP classifies and organizes phenotype descriptions for C. elegans and other nematodes. Using it, WormBase provides primary resource for phenotype annotations for C. elegans.
- Yeast Phenotype (YP) Ontology (YP) Based on YP which is the major contributor to the Ascomycete phenotype ontology, Saccharomyces Genome Database (SGD) provides single mutant phenotypes for every gene in the yeast genome.
- Fly Phenotype (FP) Ontology (FP) FP refers to FlyBase controlled vocabulary. Specifically, a structured controlled vocabulary is used for the annotation of alleles (for their mutagen etc) in FlyBase.
- Fly Anatomy (FA) Ontology (FA) FA is a structured controlled vocabulary of the anatomy of Drosophila melanogaster, used for the description of phenotypes and where a gene is expressed.
- Zebrafish Anatomy (ZA) Ontology (ZA) ZA displays anatomical terms of the zebrafish using standard anatomical nomenclature, together with affected genes.
- Xenopus Anatomy (XA) Ontology (XA) XA represents the lineage of tissues and the timing of development for frogs (Xenopus laevis and Xenopus tropicalis). It is used to annotate Xenopus gene expression patterns and mutant and morphant phenotypes.
- Arabidopsis Plant Ontology (AP) Ontology (AP) As a major contributor to Plant Ontology which describes plant anatomical and morphological structures (AN) and growth and developmental stages (DE), the Arabidopsis Information Resource (TAIR) provides arabidopsis plant ontology annotations for the model higher plant Arabidopsis thaliana.
- Enzyme Commission (EC) Ontology (EC) Each enzyme is allocated a four-digit EC number, the first three digits of which define the reaction catalysed and the fourth of which is a unique identifier (serial number). Each enzyme is also assigned a systematic name that uniquely defines the reaction catalysed.
- DrugBank ATC (DB) Ontology (DB) In the Anatomical Therapeutic Chemical (ATC) classification system, drugs are classified in groups at five different levels according to the organ or system (1st level, anatomical main group) on which they act and their therapeutic (2nd level, therapeutic subgroup), pharmacological (3rd level, pharmacological subgroup) and chemical properties (4th level, chemical subgroup; 5th level, chemical substance). Only drugs in DrugBank are considered.
- UniProtKB KeyWords (KW) Ontology (KW) Keywords in UniProtKB are controlled vocabulary, providing a summary of the entry content and are used to index UniProtKB/Swiss-Prot entries based on 10 categories (the category "Technical term" being excluded here). Each keyword is attributed manually to UniProtKB/Swiss-Prot entries and automatically to UniProtKB/TrEMBL entries (according to specific annotation rules).
- UniProtKB UniPathway (UP) Ontology (UP) UP is a fully manually curated resource for the representation and annotation of metabolic pathways, being used as controlled vocabulary for pathway annotation in UniProtKB.
Structural Domain Phenotype Ontology and its Annotations
Structural Classification of Proteins (SCOP) classifies evolutionary-related domains into Superfamily level and Family level. Using the phenotype ontologies above, we have generated the domain-centric phenotype annotations, and further identified those phenotype terms which are the most informative to annotate SCOP domains. Promisingly, domain-centric phenotypic annotations can serve as an alternative starting point to explore genotype-phenotype relationships. We provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.
- Structural Domain Disease Ontology (DO) Ontology (SDDO) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DO.txt, and the corresponding ontology:SDDO.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Human Phenotype (HP) Ontology (SDHP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2HP.txt, and the corresponding ontology:SDHP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Mouse Phenotype (MP) Ontology (SDMP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2MP.txt, and the corresponding ontology:SDMP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Worm Phenotype (WP) Ontology (SDWP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2WP.txt, and the corresponding ontology:SDWP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Yeast Phenotype (YP) Ontology (SDYP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2YP.txt, and the corresponding ontology:SDYP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Fly Phenotype (FP) Ontology (SDFP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FP.txt, and the corresponding ontology:SDFP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Fly Anatomy (FA) Ontology (SDFA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FA.txt, and the corresponding ontology:SDFA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Zebrafish Anatomy (ZA) Ontology (SDZA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2ZA.txt, and the corresponding ontology:SDZA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Xenopus Anatomy (XA) Ontology (SDXA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2XA.txt, and the corresponding ontology:SDXA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Arabidopsis Plant Ontology (AP) Ontology (SDAP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2AP.txt, and the corresponding ontology:SDAP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Enzyme Commission (EC) Ontology (SDEC) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2EC.txt, and the corresponding ontology:SDEC.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain DrugBank ATC (DB) Ontology (SDDB) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DB.txt, and the corresponding ontology:SDDB.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain UniProtKB KeyWords (KW) Ontology (SDKW) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2KW.txt, and the corresponding ontology:SDKW.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain UniProtKB UniPathway (UP) Ontology (SDUP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2UP.txt, and the corresponding ontology:SDUP.txt) and mysql tables (Domain2PO.sql.gz).
Supra-domain Phenotype Ontology and its Annotations
Although domain-centric annotations hold great promise in describing phenotypic nature of independent domains, most domains themselves may not just work alone. In multi-domain proteins, they may be combined together to form distinct domain architectures. The recombination of the existing domains is considered as one of major driving forces for phenotypic diversificaation. As an extension, we have also generated supra-domain phenotype ontology and its annotations. Compared to domain-centric phenotype ontology and annotations (SCOP domains at the Superfamily level and Family level), this version focuses on supra-domains and individual SCOP domains ONLY at the Superfamily level. Besides, in terms of individual superfamilies, their annotations from the domain-centric version may be different from those from supra-domains version. Depending on your focus, the former should be used for the consideration of both the Superfamily level and Family level, otherwise the latter should be used if you are interested in domain combinations. Also, we provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.
- Supra-domain Domain Disease Ontology (DO) Ontology (SPDO) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DO.txt, and the corresponding ontology:SPDO.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Human Phenotype (HP) Ontology (SPHO) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2HP.txt, and the corresponding ontology:SPHO.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Mouse Phenotype (MP) Ontology (SPMP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2MP.txt, and the corresponding ontology:SPMP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Worm Phenotype (WP) Ontology (SPWP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2WP.txt, and the corresponding ontology:SPWP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Yeast Phenotype (YP) Ontology (SPYP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2YP.txt, and the corresponding ontology:SPYP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Fly Phenotype (FP) Ontology (SPFP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FP.txt, and the corresponding ontology:SPFP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Fly Anatomy (FA) Ontology (SPFA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FA.txt, and the corresponding ontology:SPFA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Zebrafish Anatomy (ZA) Ontology (SPZA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2ZA.txt, and the corresponding ontology:SPZA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Xenopus Anatomy (XA) Ontology (SPXA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2XA.txt, and the corresponding ontology:SPXA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Arabidopsis Plant Ontology (AP) Ontology (SPAP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2AP.txt, and the corresponding ontology:SPAP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Enzyme Commission (EC) Ontology (SPEC) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2EC.txt, and the corresponding ontology:SPEC.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain DrugBank ATC (DB) Ontology (SPDB) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DB.txt, and the corresponding ontology:SPDB.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain UniProtKB KeyWords (KW) Ontology (SPKW) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2KW.txt, and the corresponding ontology:SPKW.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain UniProtKB UniPathway (UP) Ontology (SPUP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2UP.txt, and the corresponding ontology:SPUP.txt) and mysql tables (SP2PO.sql.gz).
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Superfamily(show details)
Superfamily domains annotated to this WP term (Not in SDWP)
Highlighted in gray are those with FDR_all>0.001
SCOP term | FDR (all) | Annotation (direct or inherited) |
SCP-like | 0 | DIRECT |
CAD & PB1 domains | 0 | DIRECT |
FtsH protease domain-like | 0 | DIRECT |
Tubby C-terminal domain-like | 0 | DIRECT |
TK C-terminal domain-like | 0 | DIRECT |
Ribosomal protein L1 | 0 | DIRECT |
RBP11-like subunits of RNA polymerase | 0 | DIRECT |
Ribosomal proteins S24e, L23 and L15e | 0 | DIRECT |
Heme-dependent catalase-like | 0 | DIRECT |
Ferritin-like | 0 | DIRECT |
Cullin repeat-like | 0 | DIRECT |
LysM domain | 0 | DIRECT |
Retrovirus zinc finger-like domains | 0 | DIRECT |
Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | DIRECT |
Cystatin/monellin | 0 | DIRECT |
Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | DIRECT |
CBD9-like | 0 | DIRECT |
Galactose mutarotase-like | 0 | DIRECT |
alpha-catenin/vinculin-like | 0 | DIRECT |
AN1-like Zinc finger | 0 | DIRECT |
MIR domain | 0 | DIRECT |
Ribosomal protein S18 | 0 | DIRECT |
Formate/glycerate dehydrogenase catalytic domain-like | 0 | DIRECT |
PUA domain-like | 0 | DIRECT |
Zn-finger domain of Sec23/24 | 0 | DIRECT |
Thiolase-like | 0 | DIRECT |
Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
HRDC-like | 0 | DIRECT |
Carbohydrate phosphatase | 0 | DIRECT |
PLC-like phosphodiesterases | 0 | DIRECT |
Integrin domains | 0 | DIRECT |
Aquaporin-like | 0 | DIRECT |
ADP-ribosylation | 0 | DIRECT |
GroEL equatorial domain-like | 0 | DIRECT |
SAND domain-like | 0 | DIRECT |
t-snare proteins | 0 | DIRECT |
ArfGap/RecO-like zinc finger | 0 | DIRECT |
R3H domain | 0 | DIRECT |
Nucleotidyltransferase | 0 | DIRECT |
ACP-like | 0 | DIRECT |
Carbon-nitrogen hydrolase | 0 | DIRECT |
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0 | DIRECT |
Nucleoside diphosphate kinase, NDK | 0 | DIRECT |
Chromo domain-like | 0 | DIRECT |
PGBD-like | 0 | DIRECT |
Transducin (alpha subunit), insertion domain | 0 | DIRECT |
ALDH-like | 0 | DIRECT |
Proton glutamate symport protein | 0 | DIRECT |
Ribosomal L27 protein-like | 0 | DIRECT |
Cation efflux protein cytoplasmic domain-like | 0 | DIRECT |
beta-lactamase/transpeptidase-like | 0 | DIRECT |
Mitochondrial carrier | 0 | DIRECT |
ISP domain | 0 | DIRECT |
Aldolase | 0 | DIRECT |
SIS domain | 0 | DIRECT |
3-carboxy-cis,cis-mucoante lactonizing enzyme | 0 | DIRECT |
PurM N-terminal domain-like | 0 | DIRECT |
Thiamin diphosphate-binding fold (THDP-binding) | 0 | DIRECT |
Galactose oxidase, central domain | 0 | DIRECT |
Class I glutamine amidotransferase-like | 0 | DIRECT |
C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
MgtE membrane domain-like | 0 | DIRECT |
Profilin (actin-binding protein) | 0 | DIRECT |
CO dehydrogenase molybdoprotein N-domain-like | 0 | DIRECT |
ENTH/VHS domain | 0 | DIRECT |
Families 57/38 glycoside transferase middle domain | 0 | DIRECT |
Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0 | DIRECT |
Activating enzymes of the ubiquitin-like proteins | 0 | DIRECT |
Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
Succinyl-CoA synthetase domains | 0 | DIRECT |
HSP90 C-terminal domain | 0 | DIRECT |
WGR domain-like | 0 | DIRECT |
cAMP-binding domain-like | 0 | DIRECT |
CRAL/TRIO N-terminal domain | 0 | DIRECT |
Kringle-like | 0 | DIRECT |
Acetyl-CoA synthetase-like | 0 | DIRECT |
Doublecortin (DC) | 0 | DIRECT |
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | DIRECT |
eIF4e-like | 0 | DIRECT |
Citrate synthase | 0 | DIRECT |
Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
Terpenoid synthases | 0 | DIRECT |
DNA repair protein MutS, domain III | 0 | DIRECT |
Oxysterol-binding protein-like | 0 | DIRECT |
Aminoacid dehydrogenase-like, N-terminal domain | 0 | DIRECT |
F1F0 ATP synthase subunit C | 0 | DIRECT |
LEM domain | 0 | DIRECT |
PHM/PNGase F | 0 | DIRECT |
Actin-like ATPase domain | 0 | DIRECT |
PreATP-grasp domain | 0 | DIRECT |
dsRNA-binding domain-like | 0 | DIRECT |
PLP-binding barrel | 0 | DIRECT |
5' to 3' exonuclease, C-terminal subdomain | 0 | DIRECT |
PK beta-barrel domain-like | 0 | DIRECT |
Phoshotransferase/anion transport protein | 0 | DIRECT |
VPS9 domain | 0 | DIRECT |
Creatinase/prolidase N-terminal domain | 0 | DIRECT |
Arginase/deacetylase | 0 | DIRECT |
Surp module (SWAP domain) | 0 | DIRECT |
Complement control module/SCR domain | 0 | DIRECT |
SWIB/MDM2 domain | 0 | DIRECT |
Spectrin repeat | 0 | DIRECT |
Insulin-like | 0 | DIRECT |
L30e-like | 0 | DIRECT |
SPOC domain-like | 0 | DIRECT |
Phosphoglucomutase, first 3 domains | 0 | DIRECT |
Tim10-like | 0 | DIRECT |
Skp1 dimerisation domain-like | 0 | DIRECT |
FAD-linked oxidases, C-terminal domain | 0 | DIRECT |
Rap/Ran-GAP | 0 | DIRECT |
PIN domain-like | 0 | DIRECT |
BEACH domain | 0 | DIRECT |
DEATH domain | 0 | DIRECT |
YWTD domain | 0 | DIRECT |
S-adenosylmethionine synthetase | 0 | DIRECT |
YbiA-like | 0 | DIRECT |
Single hybrid motif | 0 | DIRECT |
Lipovitellin-phosvitin complex, superhelical domain | 0 | DIRECT |
Nucleoporin domain | 0 | DIRECT |
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
MFPT repeat-like | 0 | DIRECT |
GAS2 domain-like | 0 | DIRECT |
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
Terpenoid cyclases/Protein prenyltransferases | 0 | DIRECT |
SMAD MH1 domain | 0 | DIRECT |
PEP carboxykinase N-terminal domain | 0 | DIRECT |
Tricorn protease domain 2 | 0 | DIRECT |
Hormone receptor domain | 0 | DIRECT |
GroEL-intermediate domain like | 0 | DIRECT |
Sec1/munc18-like (SM) proteins | 0 | DIRECT |
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
Carbonic anhydrase | 0 | DIRECT |
Band 7/SPFH domain | 0 | DIRECT |
ARID-like | 0 | DIRECT |
Isocitrate/Isopropylmalate dehydrogenase-like | 0 | DIRECT |
GAT-like domain | 0 | DIRECT |
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
Transducin (heterotrimeric G protein), gamma chain | 0 | DIRECT |
alpha/beta knot | 0 | DIRECT |
Sec63 N-terminal domain-like | 0 | DIRECT |
Sec7 domain | 0 | DIRECT |
beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | DIRECT |
Phosphoenolpyruvate/pyruvate domain | 0 | DIRECT |
14-3-3 protein | 0 | DIRECT |
Nop domain | 0 | DIRECT |
Tubulin nucleotide-binding domain-like | 0 | DIRECT |
LDH C-terminal domain-like | 0 | DIRECT |
Carboxypeptidase regulatory domain-like | 0 | DIRECT |
N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
Cytochrome c | 0 | DIRECT |
Blood coagulation inhibitor (disintegrin) | 0 | DIRECT |
PAP/OAS1 substrate-binding domain | 0 | DIRECT |
Helical domain of Sec23/24 | 0 | DIRECT |
Subtilisin-like | 0 | DIRECT |
GroES-like | 0 | DIRECT |
Pepsin inhibitor-3 | 0 | DIRECT |
Small-conductance potassium channel | 0 | DIRECT |
HSP20-like chaperones | 0 | DIRECT |
Hypothetical protein c14orf129, hspc210 | 0 | DIRECT |
Integrin alpha N-terminal domain | 0 | DIRECT |
lambda repressor-like DNA-binding domains | 0 | DIRECT |
2Fe-2S ferredoxin-like | 0 | DIRECT |
HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
Cdc48 domain 2-like | 0 | DIRECT |
Thyroglobulin type-1 domain | 0 | DIRECT |
Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
PABC (PABP) domain | 0 | DIRECT |
Heme-dependent peroxidases | 0 | DIRECT |
SAICAR synthase-like | 0 | DIRECT |
Restriction endonuclease-like | 0 | DIRECT |
Chitinase insertion domain | 0 | DIRECT |
Clathrin adaptor appendage domain | 0 | DIRECT |
Ran binding protein zinc finger-like | 0 | DIRECT |
Cu,Zn superoxide dismutase-like | 0 | DIRECT |
Radical SAM enzymes | 0 | DIRECT |
Ribosomal protein L10-like | 0 | DIRECT |
Glycolipid transfer protein, GLTP | 0 | DIRECT |
Clc chloride channel | 0 | DIRECT |
DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
Tubulin C-terminal domain-like | 0 | DIRECT |
Smc hinge domain | 0 | DIRECT |
PYP-like sensor domain (PAS domain) | 0 | DIRECT |
Bacterial exopeptidase dimerisation domain | 0 | DIRECT |
Periplasmic binding protein-like II | 0 | DIRECT |
Chaperone J-domain | 0 | DIRECT |
Ribulose-phoshate binding barrel | 0 | DIRECT |
Annexin | 0 | DIRECT |
HCP-like | 0 | DIRECT |
Class II aaRS ABD-related | 0 | DIRECT |
PEBP-like | 0 | DIRECT |
Putative DNA-binding domain | 0 | DIRECT |
WWE domain | 0 | DIRECT |
JAB1/MPN domain | 0 | DIRECT |
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | DIRECT |
Subdomain of clathrin and coatomer appendage domain | 0 | DIRECT |
Pentein | 0 | DIRECT |
FAD-dependent thiol oxidase | 0 | DIRECT |
FAD-binding/transporter-associated domain-like | 0 | DIRECT |
Hedgehog/intein (Hint) domain | 0 | DIRECT |
Lamin A/C globular tail domain | 0 | DIRECT |
PurM C-terminal domain-like | 0 | DIRECT |
Ribosomal protein S10 | 0 | DIRECT |
Acyl-CoA dehydrogenase NM domain-like | 0 | DIRECT |
Intermediate filament protein, coiled coil region | 0 | DIRECT |
Molybdenum cofactor-binding domain | 0 | DIRECT |
C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
GroEL apical domain-like | 0 | DIRECT |
Domain of poly(ADP-ribose) polymerase | 0 | DIRECT |
Second domain of FERM | 0 | DIRECT |
Fibrinogen C-terminal domain-like | 0 | DIRECT |
Glutathione synthetase ATP-binding domain-like | 0 | DIRECT |
GYF domain | 0 | DIRECT |
Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
Zn-binding ribosomal proteins | 0 | DIRECT |
Histone-fold | 0 | DIRECT |
Acid phosphatase/Vanadium-dependent haloperoxidase | 0 | DIRECT |
PEP carboxykinase-like | 0 | DIRECT |
TGS-like | 0 | DIRECT |
Diaminopimelate epimerase-like | 0 | DIRECT |
Troponin coil-coiled subunits | 0 | DIRECT |
MOSC N-terminal domain-like | 0 | DIRECT |
FF domain | 0 | DIRECT |
Ribokinase-like | 0 | DIRECT |
Polo-box domain | 0 | DIRECT |
ThrRS/AlaRS common domain | 0 | DIRECT |
Protease propeptides/inhibitors | 0 | DIRECT |
FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | DIRECT |
CO dehydrogenase ISP C-domain like | 0 | DIRECT |
Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | DIRECT |
Translational machinery components | 0 | DIRECT |
Invertebrate chitin-binding proteins | 0 | DIRECT |
Rudiment single hybrid motif | 0 | DIRECT |
L-aspartase-like | 0 | DIRECT |
DNA ligase/mRNA capping enzyme, catalytic domain | 0 | DIRECT |
Outer arm dynein light chain 1 | 0 | DIRECT |
ValRS/IleRS/LeuRS editing domain | 0 | DIRECT |
Cullin homology domain | 0 | DIRECT |
Elafin-like | 0 | DIRECT |
Cadherin-like | 0 | DIRECT |
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | DIRECT |
Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | DIRECT |
NagB/RpiA/CoA transferase-like | 0 | DIRECT |
P-loop containing nucleoside triphosphate hydrolases | 0.00000007798 | DIRECT |
PH domain-like | 0.00001907 | DIRECT |
PDZ domain-like | 0.008703 | INHERITED FROM: acetylcholinesterase inhibitor response variant || aldicarb response variant || protein expression variant |
TPR-like | 0.01221 | INHERITED FROM: positive chemotaxis defective || light body touch resistant || ivermectin resistant || ivermectin response variant || antihelmintic response variant |
Periplasmic binding protein-like I | 0.01392 | INHERITED FROM: alkaline pH chemotaxis variant || mechanosensation variant || magnesium chemotaxis defective || carbon dioxide avoidance variant || iodide chemotaxis defective || memory retention defective || thermosensory behavior variant || chemosensory response variant || thermotaxis variant || diacetyl chemotaxis variant || aqueous chemosensory response variant || organism temperature response variant || chemotaxis variant || lithium chemotaxis defective || chemosensory behavior variant || AWC odorant chemotaxis variant || AWC odorant chemotaxis defective || benzaldehyde chemotaxis variant || bromide chemotaxis variant || iodide chemotaxis variant || organism environmental stimulus response variant || aqueous positive chemotaxis variant || bromide chemotaxis defective || second messenger mediated signaling variant |
ARM repeat | 0.01805 | INHERITED FROM: RNAi response variant || gene expression variant || sick || sexually dimorphic physiology variant || organism metabolism processing variant || protein expression variant |
ABC transporter transmembrane region | 0.01964 | INHERITED FROM: metal response variant || RNAi response variant || colchicine hypersensitive || cadmium response variant || RNAi resistant || organism environmental stimulus response variant |
PapD-like | 0.02301 | INHERITED FROM: developmental growth variant || slow growth || dauer metabolism variant || larval growth variant || dauer lifespan extended || fat content variant || dauer lifespan variant || larval arrest || lipid metabolism variant |
Protein kinase-like (PK-like) | 0.04522 | INHERITED FROM: protein phosphorylation variant || alkaline pH chemotaxis variant || mechanosensation variant || metal response variant || chemical response variant || colchicine resistant || aldicarb response variant || drug induced gene expression variant || chemosensory response variant || pathogen induced gene expression variant || mid larval arrest || octanol chemotaxis defective || chemotaxis variant || conflicting sensory integration variant || kinase activity reduced || protein modification variant || egg laying response to food variant || metabolic pathway variant || chemosensory behavior variant || anoxia resistant || lipid synthesis increased || dauer development variant || positive chemotaxis variant || organism osmostic stress hypersensitive || protein subcellular localization variant || protein expression variant || organism environmental stimulus response variant || life span variant || second messenger mediated signaling variant || protein phosphorylation reduced |
Nucleic acid-binding proteins | 0.04629 | INHERITED FROM: hydroxyurea hypersensitive || nonsense mRNA accumulation || hypoxia resistant || mRNA surveillance defective || hydroxyurea response variant || sick || hermaphrodite physiology variant || sexually dimorphic physiology variant |
Homeodomain-like | 0.05168 | INHERITED FROM: carbon dioxide avoidance variant || ectopic expression transgene || imipramine resistant || level of transgene expression variant || egg laying imipramine resistant || inhibitor of serotonin uptake variant || adrenergic receptor antagonist response variant || growth rate variant || organism metabolism processing variant || protein degradation variant || carbon dioxide response variant |
WD40 repeat-like | 0.06117 | INHERITED FROM: osmotic avoidance variant || late larval arrest || early larval arrest || aldicarb response variant || protein protein interaction variant || protein aggregation induced behavior variant || hermaphrodite physiology variant || sexually dimorphic physiology variant || organism metabolism processing variant || antimicrobial gene expression variant || protein aggregation variant |
CCCH zinc finger | 0.06793 | INHERITED FROM: ectopic expression transgene || gene expression variant || transgene expression variant || mRNA expression ectopic |
FYVE/PHD zinc finger | 0.07678 | INHERITED FROM: ectopic expression transgene || organism UV response variant || gene expression variant || protein methylation variant || protein modification variant || organism UV hypersensitive || organism metabolism processing variant |
Translation proteins | 0.08478 | INHERITED FROM: protein phosphorylation variant || protein phosphorylation increased || gene expression variant || protein protein interaction variant || receptor mediated endocytosis defective || transgene expression variant || proteasome core activity variant || mRNA levels increased || hermaphrodite physiology variant || sexually dimorphic physiology variant || organism metabolism processing variant || protein aggregation variant || oocyte physiology variant |
"Winged helix" DNA-binding domain | 0.0937 | INHERITED FROM: anesthetic response variant || paraquat hypersensitive || protein expression increased || germline transgene silencing variant || protein protein interaction variant || spontaneous mutation rate increased || protein aggregation induced behavior variant || shortened life span || chemical hypersensitive || organism metabolism processing variant || life span variant || protein aggregation variant |
Ankyrin repeat | 0.09895 | INHERITED FROM: organism heat response variant || odorant negative chemotaxis defective || octanol chemotaxis defective || octanol chemotaxis variant || chemotaxis variant |
HLH, helix-loop-helix DNA-binding domain | 0.09914 | INHERITED FROM: aqueous positive chemotaxis defective || ectopic expression transgene || RNA expression variant || pathogen resistance increased || hypoxia response variant || fungal resistance increased || organism metabolism processing variant || lysine chemotaxis defective || gene expression level reduced |
Nucleotide cyclase | 0.09914 | INHERITED FROM: cation positive chemotaxis defective || alkaline pH chemotaxis variant || magnesium chemotaxis defective || anion positive chemotaxis defective || iodide chemotaxis defective || osmotic avoidance variant || anion positive chemotaxis variant || chemosensory response variant || diacetyl chemotaxis variant || cation positive chemotaxis variant || aqueous chemosensory response variant || chemotaxis variant || lithium chemotaxis defective || chemosensory behavior variant || AWC odorant chemotaxis variant || AWC odorant chemotaxis defective || positive chemotaxis variant || bromide chemotaxis variant || iodide chemotaxis variant || organism environmental stimulus response variant || bromide chemotaxis defective || second messenger mediated signaling variant || carbon dioxide response variant |
SMAD/FHA domain | 0.1059 | INHERITED FROM: aldicarb response variant || fat content reduced |
BRCT domain | 0.1059 | INHERITED FROM: organism ionizing radiation response variant |
Calcium ATPase, transmembrane domain M | 0.1182 | INHERITED FROM: lipid composition variant || nicotine hypersensitive |
SH3-domain | 0.123 | INHERITED FROM: protein phosphorylation variant || aldicarb response variant || protein expression reduced || protein expression variant || protein metabolism variant |
Metal cation-transporting ATPase, ATP-binding domain N | 0.132 | INHERITED FROM: lipid composition variant || nicotine hypersensitive || organism environmental stimulus response variant |
Regulator of G-protein signaling, RGS | 0.132 | INHERITED FROM: mechanosensation variant || chemotaxis variant || negative chemotaxis variant |
EGF/Laminin | 0.1351 | INHERITED FROM: odorant negative chemotaxis defective || octanol chemotaxis defective || octanol chemotaxis variant |
Calcium ATPase, transduction domain A | 0.147 | INHERITED FROM: nicotine hypersensitive || organism environmental stimulus response variant |
Acid proteases | 0.147 | INHERITED FROM: transgene subcellular localization variant || protein interaction variant || osmotic integrity variant || hypoosmotic shock hypersensitive || gene expression variant || protein protein interaction variant || transgene expression variant || organism metabolism processing variant || protein aggregation variant |
Cysteine-rich domain | 0.1548 | INHERITED FROM: odorant chemosensory response variant || thermosensory behavior variant || aldicarb response variant || drug induced gene expression variant || thermotaxis variant || organism temperature response variant || response to injury variant || positive chemotaxis variant || organism metabolism processing variant || protein subcellular localization variant || bacterially unswollen || antimicrobial gene expression variant || odorant positive chemotaxis variant |
Quinoprotein alcohol dehydrogenase-like | 0.1639 | INHERITED FROM: drug response variant || mid larval arrest || hypoxia response variant || mRNA levels increased || protein degradation variant || L2 arrest |
Multidrug efflux transporter AcrB transmembrane domain | 0.1689 | INHERITED FROM: odorant chemosensory response variant || odorant positive chemotaxis defective || egg integrity defective early emb || positive chemotaxis defective || embryo osmotic integrity defective early emb |
Cytochrome P450 | 0.1818 | INHERITED FROM: metal response variant || metabolite content decreased || cadmium response variant |
ClpP/crotonase | 0.1826 | INHERITED FROM: level of transgene expression variant || fat content variant || lipid metabolism variant |
DBL homology domain (DH-domain) | 0.1826 | INHERITED FROM: pathogen resistance increased || aldicarb response variant || organism pathogen response variant || bacterially unswollen || organism environmental stimulus response variant |
HMG-box | 0.1826 | INHERITED FROM: maintenance of gene silencing variant || transgene expression variant |
E set domains | 0.186 | INHERITED FROM: paraquat hypersensitive |
(Trans)glycosidases | 0.1925 | INHERITED FROM: pathogen susceptibility increased |
Cyclin-like | 0.2365 | INHERITED FROM: protein phosphorylation variant || level of transgene expression variant || protein phosphorylation reduced |
Cysteine proteinases | 0.2428 | INHERITED FROM: paraquat hypersensitive || protein interaction variant || osmotic integrity variant || hypoosmotic shock hypersensitive || protein protein interaction variant || pattern of transgene expression variant || organism metabolism processing variant || protein aggregation variant |
6-phosphogluconate dehydrogenase C-terminal domain-like | 0.2511 | INHERITED FROM: fat content variant || lipid metabolism variant |
Bromodomain | 0.2511 | INHERITED FROM: acute functional tolerance to alcohol defective || anesthetic response variant || drug adaptation variant || ethanol resistant || organism UV response variant || gene expression variant || anesthetic resistant || sick || organism UV hypersensitive || organism metabolism processing variant |
Tudor/PWWP/MBT | 0.2511 | INHERITED FROM: pattern of transgene expression variant |
POZ domain | 0.2601 | INHERITED FROM: L1 arrest || early larval arrest || protein aggregation induced behavior variant || resistant to protein aggregation induced paralysis || chemical hypersensitive |
RNA-binding domain, RBD | 0.2709 | INHERITED FROM: maintenance of gene silencing variant || no induction of antimicrobial peptide expression after infection || innate immune response variant || RNA expression variant || alternative splicing variant || RNA processing variant || sick || mRNA export variant || organism metabolism processing variant || RNA metabolism variant || antimicrobial gene expression variant || starvation induced apoptosis variant |
Lipocalins | 0.2779 | INHERITED FROM: paraquat hypersensitive || fat content variant || fat content increased || lipid metabolism variant |
SNARE-like | 0.2789 | INHERITED FROM: transgene subcellular localization variant || acetylcholinesterase inhibitor resistant || gene expression variant || transgene expression variant || aldicarb resistant || sick || pattern of transgene expression variant || organism metabolism processing variant |
Metallo-dependent phosphatases | 0.2804 | INHERITED FROM: germ cell resistant ionizing radiation || radiation induced germ cell apoptosis resistant |
Cation efflux protein transmembrane domain-like | 0.343 | INHERITED FROM: metal response variant || manganese toxicity resistant || manganese response variant || cadmium hypersensitive |
Translation proteins SH3-like domain | 0.343 | INHERITED FROM: early larval arrest || gene expression variant || transgene expression variant || organism metabolism processing variant |
PX domain | 0.343 | INHERITED FROM: protein expression reduced || protein subcellular localization variant || protein expression variant |
HAD-like | 0.3625 | INHERITED FROM: nicotine hypersensitive |
Nicotinic receptor ligand binding domain-like | 0.375 | INHERITED FROM: mechanosensation variant || chemical response variant || slowing response on food variant || sodium chloride chemotaxis variant || nicotine resistant || thermosensory behavior variant || cholinergic agonist resistant || drug response variant || chemosensory response variant || hypoosmotic shock hypersensitive || organism temperature response variant || chemotaxis variant || antihelmintic response variant || chemosensory behavior variant || AWC odorant chemotaxis variant || positive chemotaxis variant || selenium response variant || DMPP response variant || benzaldehyde chemotaxis variant || organism environmental stimulus response variant |
Ubiquitin-like | 0.3922 | INHERITED FROM: heteroplasmy || protein interaction variant || protein protein interaction variant || organism metabolism processing variant || protein aggregation variant |
Neurotransmitter-gated ion-channel transmembrane pore | 0.4114 | INHERITED FROM: mechanosensation variant || chemical response variant || slowing response on food variant || sodium chloride chemotaxis variant || nicotine resistant || thermosensory behavior variant || cholinergic agonist resistant || drug response variant || chemosensory response variant || hypoosmotic shock hypersensitive || organism temperature response variant || chemotaxis variant || antihelmintic response variant || chemosensory behavior variant || AWC odorant chemotaxis variant || positive chemotaxis variant || selenium response variant || DMPP response variant || benzaldehyde chemotaxis variant || organism environmental stimulus response variant |
RNI-like | 0.4179 | INHERITED FROM: resistant to protein aggregation induced paralysis |
FKBP-like | 0.4192 | INHERITED FROM: transgene subcellular localization variant || protein interaction variant || protein protein interaction variant || pattern of transgene expression variant || protein aggregation variant |
HD-domain/PDEase-like | 0.4192 | INHERITED FROM: thermosensory behavior variant || thermotaxis variant || organism temperature response variant |
Class II aaRS and biotin synthetases | 0.4353 | INHERITED FROM: oxygen response variant || gene expression variant || hypoxia response variant || hypoxia resistant || receptor mediated endocytosis defective || transgene expression variant || hermaphrodite physiology variant || sexually dimorphic physiology variant || organism metabolism processing variant || organism environmental stimulus response variant || oocyte physiology variant |
DHS-like NAD/FAD-binding domain | 0.4642 | INHERITED FROM: protein acetylation variant || metabolic pathway variant |
Myosin rod fragments | 0.4642 | INHERITED FROM: drug resistant || hermaphrodite physiology variant || sexually dimorphic physiology variant |
PRTase-like | 0.4642 | INHERITED FROM: Fluorouracil resistant || drug resistant |
Hect, E3 ligase catalytic domain | 0.4642 | INHERITED FROM: transgene subcellular localization variant || protein interaction variant || gene expression variant || protein protein interaction variant || protein aggregation induced behavior variant || transgene expression variant || cell stress response variant || pattern of transgene expression variant || organism metabolism processing variant || germ cell ionizing radiation response variant || protein aggregation variant |
Ribosomal protein S5 domain 2-like | 0.4963 | INHERITED FROM: early larval arrest |
Galactose-binding domain-like | 0.4963 | INHERITED FROM: protein interaction variant || protein protein interaction variant || protein aggregation variant |
Cystine-knot cytokines | 0.5003 | INHERITED FROM: nicotine response variant || levamisole response variant |
WW domain | 0.5003 | INHERITED FROM: maintenance of gene silencing variant |
Sm-like ribonucleoproteins | 0.5003 | INHERITED FROM: unfolded protein response variant || organism heat response variant || gene expression variant || receptor mediated endocytosis defective || transgene expression variant || sick || hermaphrodite physiology variant || pattern of transgene expression variant || sexually dimorphic physiology variant || protein subcellular localization variant || life span variant |
SH2 domain | 0.5041 | INHERITED FROM: level of protein expression variant || protein expression reduced || protein expression variant |
Calpain large subunit, middle domain (domain III) | 0.5108 | INHERITED FROM: metabolic pathway variant || protein degradation variant || protein metabolism variant |
Riboflavin synthase domain-like | 0.5108 | INHERITED FROM: pattern protein expression variant |
Ferredoxin reductase-like, C-terminal NADP-linked domain | 0.5108 | INHERITED FROM: pattern protein expression variant |
FAD/NAD(P)-binding domain | 0.5223 | INHERITED FROM: ATP levels reduced || pesticide response variant || ATP levels variant || life span variant |
FAD-linked reductases, C-terminal domain | 0.5355 | INHERITED FROM: life span variant |
Voltage-gated potassium channels | 0.5365 | INHERITED FROM: mechanosensation variant || serotonin response variant || positive chemotaxis defective || serotonin resistant || adrenergic receptor antagonist response variant || growth rate variant || protein degradation variant |
SAM/Pointed domain | 0.5432 | INHERITED FROM: aldicarb response variant || gene expression level reduced |
Nucleotidylyl transferase | 0.5432 | INHERITED FROM: oxygen response variant || paraquat resistant || transgene expression increased || hypoxia response variant || hypoxia resistant || organism metabolism processing variant || organism environmental stimulus response variant |
UBC-like | 0.5454 | INHERITED FROM: transgene subcellular localization variant || late larval arrest || protein interaction variant || protein protein interaction variant || sick || pattern of transgene expression variant || organism metabolism processing variant || protein aggregation variant |
SET domain | 0.5454 | INHERITED FROM: maintenance of gene silencing variant || dosage compensation variant || RNAi response variant || ectopic expression antibody || histone methylation variant || gene expression variant || spontaneous mutation rate increased || protein methylation variant || protein modification variant || shortened life span || pattern of transgene expression variant || organism metabolism processing variant || protein metabolism variant || life span variant |
Seven-hairpin glycosidases | 0.5661 | INHERITED FROM: extended life span || protein protein interaction variant || protein aggregation variant |
Multidrug resistance efflux transporter EmrE | 0.5717 | INHERITED FROM: pathogen resistance increased || bacterially unswollen |
PLP-dependent transferases | 0.5893 | INHERITED FROM: germ cell resistant ionizing radiation || radiation induced germ cell apoptosis resistant |
C2 domain (Calcium/lipid-binding domain, CaLB) | 0.6053 | INHERITED FROM: drug resistant || chemical response variant || RNAi response variant || drug induced gene expression variant || response to injury variant || gonad sheath contractions variant || aging variant || growth rate variant || cell stress response variant || gonad sheath contraction rate reduced || protein subcellular localization variant || protein expression variant || organism environmental stimulus response variant || antimicrobial gene expression variant || somatic sheath physiology variant |
Di-copper centre-containing domain | 0.6214 | INHERITED FROM: organism stress response variant || organism ionizing radiation response variant || cell stress response variant || cell ionizing radiation response variant || germ cell ionizing radiation response variant |
Nucleotide-binding domain | 0.6214 | INHERITED FROM: extended life span |
KA1-like | 0.6214 | INHERITED FROM: RNA expression variant |
HIT/MYND zinc finger-like | 0.6475 | INHERITED FROM: pattern of transgene expression variant |
S-adenosyl-L-methionine-dependent methyltransferases | 0.6484 | INHERITED FROM: cell gamma ray response variant || organism gamma ray response variant || gamma ray induced apoptosis increased |
MFS general substrate transporter | 0.6858 | INHERITED FROM: organism high sodium chloride hypersensitive |
4Fe-4S ferredoxins | 0.686 | INHERITED FROM: transgene expression increased || life span variant |
S15/NS1 RNA-binding domain | 0.686 | INHERITED FROM: transgene expression increased |
Frizzled cysteine-rich domain | 0.686 | INHERITED FROM: antibody staining variant || transgene expression reduced |
GST C-terminal domain-like | 0.6916 | INHERITED FROM: organism stress response variant || metal response variant || organism electrophilic stress hypersensitive || organism heat hypersensitive || enzyme activity reduced || enzyme activity variant || organism environmental stimulus response variant || cadmium hypersensitive |
alpha/beta-Hydrolases | 0.7487 | INHERITED FROM: acetylcholinesterase reduced || acetylcholinesterase activity variant |
EF-hand | 0.7546 | INHERITED FROM: protein interaction variant || aldicarb response variant || gonad sheath contractions variant || osmotic stress response variant || protein aggregation variant || somatic sheath physiology variant |
ADC-like | 0.7553 | INHERITED FROM: protein interaction variant || protein protein interaction variant || metabolic pathway variant || protein metabolism variant || transgene expression reduced || protein aggregation variant |
MIT domain | 0.7553 | INHERITED FROM: protein interaction variant || protein protein interaction variant || protein aggregation variant |
Clavaminate synthase-like | 0.8079 | INHERITED FROM: histone methylation variant || protein methylation variant || life span variant |
NAD kinase/diacylglycerol kinase-like | 0.813 | INHERITED FROM: organism stress response variant || thermosensory behavior variant || thermotaxis variant |
Cyclophilin-like | 0.8208 | INHERITED FROM: transgene subcellular localization variant || protein interaction variant || gene expression variant || protein protein interaction variant || transgene expression variant || pattern of transgene expression variant || protein aggregation variant |
CoA-dependent acyltransferases | 0.8208 | INHERITED FROM: organism metabolism processing variant |
UBA-like | 0.8318 | INHERITED FROM: protein protein interaction variant || protein aggregation variant |
SNF-like | 0.8516 | INHERITED FROM: drug hypersensitive |
Leucine zipper domain | 0.857 | INHERITED FROM: mRNA levels reduced || pathogen susceptibility increased || level of transgene expression variant || pore forming toxin response variant || mRNA expression variant || transgene expression reduced |
GTPase activation domain, GAP | 0.8655 | INHERITED FROM: protein expression variant |
Thioredoxin-like | 0.895 | INHERITED FROM: organism stress response variant || metal response variant || organism electrophilic stress hypersensitive || paraquat response variant || organism heat hypersensitive || enzyme activity reduced || enzyme activity variant || cadmium hypersensitive |
Glucocorticoid receptor-like (DNA-binding domain) | 0.9043 | INHERITED FROM: SDS sensitive dauer || level of transgene expression variant || dauer resistance to harsh conditions variant || gene expression level high || fat content increased || gene expression level reduced || transgene expression reduced |
p53-like transcription factors | 0.9044 | INHERITED FROM: ectopic expression transgene || level of transgene expression variant || gene expression level reduced |
Immunoglobulin | 0.9093 | INHERITED FROM: aldicarb response variant || growth rate variant || protein degradation variant |
Ribonuclease PH domain 2-like | 0.9313 | INHERITED FROM: early larval arrest |
DNA/RNA polymerases | 0.9349 | INHERITED FROM: DNA repair variant || DNA metabolism variant |
Saposin | 0.9568 | INHERITED FROM: germ cell resistant ionizing radiation || radiation induced germ cell apoptosis resistant || level of transgene expression variant || pathogen load variant || increased pathogen survival || germ cell ionizing radiation response variant || transgene expression reduced |
Ribonuclease H-like | 0.9727 | INHERITED FROM: maintenance of gene silencing variant || RNAi response variant || somatic transgene silencing variant || RNA expression variant || RNAi enhanced || 21U RNA expression variant || siRNA expression variant |
PAZ domain | 0.99 | INHERITED FROM: maintenance of gene silencing variant || RNAi response variant || somatic transgene silencing variant || RNA expression variant || RNAi enhanced || 21U RNA expression variant || mRNA levels increased || siRNA expression variant |
RING/U-box | 1 | INHERITED FROM: transgene subcellular localization variant || protein interaction variant || gene expression variant || protein protein interaction variant || organism ionizing radiation response variant || pattern of transgene expression variant || organism metabolism processing variant || germ cell hypersensitive ionizing radiation || cell ionizing radiation response variant || germ cell ionizing radiation response variant || protein aggregation variant |
Nuclear receptor ligand-binding domain | 1 | INHERITED FROM: SDS sensitive dauer || level of transgene expression variant || dauer resistance to harsh conditions variant || gene expression level high || fat content increased || gene expression level reduced || transgene expression reduced |
Bet v1-like | 1 | INHERITED FROM: growth rate variant |
B-box zinc-binding domain | 1 | INHERITED FROM: transgene subcellular localization variant || protein interaction variant || gene expression variant || protein protein interaction variant || transgene expression variant || organism metabolism processing variant || protein aggregation variant |
F-box domain | 1 | INHERITED FROM: resistant to protein aggregation induced paralysis |
Snake toxin-like | 1 | INHERITED FROM: fat content reduced |
Ligand-binding domain in the NO signalling and Golgi transport | 1 | INHERITED FROM: carbon dioxide avoidance variant || carbon dioxide response variant |
Family A G protein-coupled receptor-like | 1 | INHERITED FROM: male tail curling serotonin variant || serotonin induced fat reduction variant || locomotion rate serotonin variant || serotonin induced pumping variant |
beta-beta-alpha zinc fingers | 1 | INHERITED FROM: imipramine resistant || egg laying imipramine resistant || inhibitor of serotonin uptake variant || organism metabolism processing variant |
SCOP term | FDR (all) | Annotation (direct or inherited) |
SCP-like | 0 | Direct |
CAD & PB1 domains | 0 | Direct |
FtsH protease domain-like | 0 | Direct |
Tubby C-terminal domain-like | 0 | Direct |
TK C-terminal domain-like | 0 | Direct |
Ribosomal protein L1 | 0 | Direct |
RBP11-like subunits of RNA polymerase | 0 | Direct |
Ribosomal proteins S24e, L23 and L15e | 0 | Direct |
Heme-dependent catalase-like | 0 | Direct |
Ferritin-like | 0 | Direct |
Cullin repeat-like | 0 | Direct |
LysM domain | 0 | Direct |
Retrovirus zinc finger-like domains | 0 | Direct |
Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | Direct |
Cystatin/monellin | 0 | Direct |
Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | Direct |
CBD9-like | 0 | Direct |
Galactose mutarotase-like | 0 | Direct |
alpha-catenin/vinculin-like | 0 | Direct |
AN1-like Zinc finger | 0 | Direct |
MIR domain | 0 | Direct |
Ribosomal protein S18 | 0 | Direct |
Formate/glycerate dehydrogenase catalytic domain-like | 0 | Direct |
PUA domain-like | 0 | Direct |
Zn-finger domain of Sec23/24 | 0 | Direct |
Thiolase-like | 0 | Direct |
Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
HRDC-like | 0 | Direct |
Carbohydrate phosphatase | 0 | Direct |
PLC-like phosphodiesterases | 0 | Direct |
Integrin domains | 0 | Direct |
Aquaporin-like | 0 | Direct |
ADP-ribosylation | 0 | Direct |
GroEL equatorial domain-like | 0 | Direct |
SAND domain-like | 0 | Direct |
t-snare proteins | 0 | Direct |
ArfGap/RecO-like zinc finger | 0 | Direct |
R3H domain | 0 | Direct |
Nucleotidyltransferase | 0 | Direct |
ACP-like | 0 | Direct |
Carbon-nitrogen hydrolase | 0 | Direct |
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0 | Direct |
Nucleoside diphosphate kinase, NDK | 0 | Direct |
Chromo domain-like | 0 | Direct |
PGBD-like | 0 | Direct |
Transducin (alpha subunit), insertion domain | 0 | Direct |
ALDH-like | 0 | Direct |
Proton glutamate symport protein | 0 | Direct |
Ribosomal L27 protein-like | 0 | Direct |
Cation efflux protein cytoplasmic domain-like | 0 | Direct |
beta-lactamase/transpeptidase-like | 0 | Direct |
Mitochondrial carrier | 0 | Direct |
ISP domain | 0 | Direct |
Aldolase | 0 | Direct |
SIS domain | 0 | Direct |
3-carboxy-cis,cis-mucoante lactonizing enzyme | 0 | Direct |
PurM N-terminal domain-like | 0 | Direct |
Thiamin diphosphate-binding fold (THDP-binding) | 0 | Direct |
Galactose oxidase, central domain | 0 | Direct |
Class I glutamine amidotransferase-like | 0 | Direct |
C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
MgtE membrane domain-like | 0 | Direct |
Profilin (actin-binding protein) | 0 | Direct |
CO dehydrogenase molybdoprotein N-domain-like | 0 | Direct |
ENTH/VHS domain | 0 | Direct |
Families 57/38 glycoside transferase middle domain | 0 | Direct |
Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0 | Direct |
Activating enzymes of the ubiquitin-like proteins | 0 | Direct |
Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
Succinyl-CoA synthetase domains | 0 | Direct |
HSP90 C-terminal domain | 0 | Direct |
WGR domain-like | 0 | Direct |
cAMP-binding domain-like | 0 | Direct |
CRAL/TRIO N-terminal domain | 0 | Direct |
Kringle-like | 0 | Direct |
Acetyl-CoA synthetase-like | 0 | Direct |
Doublecortin (DC) | 0 | Direct |
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | Direct |
eIF4e-like | 0 | Direct |
Citrate synthase | 0 | Direct |
Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
Terpenoid synthases | 0 | Direct |
DNA repair protein MutS, domain III | 0 | Direct |
Oxysterol-binding protein-like | 0 | Direct |
Aminoacid dehydrogenase-like, N-terminal domain | 0 | Direct |
F1F0 ATP synthase subunit C | 0 | Direct |
LEM domain | 0 | Direct |
PHM/PNGase F | 0 | Direct |
Actin-like ATPase domain | 0 | Direct |
PreATP-grasp domain | 0 | Direct |
dsRNA-binding domain-like | 0 | Direct |
PLP-binding barrel | 0 | Direct |
5' to 3' exonuclease, C-terminal subdomain | 0 | Direct |
PK beta-barrel domain-like | 0 | Direct |
Phoshotransferase/anion transport protein | 0 | Direct |
VPS9 domain | 0 | Direct |
Creatinase/prolidase N-terminal domain | 0 | Direct |
Arginase/deacetylase | 0 | Direct |
Surp module (SWAP domain) | 0 | Direct |
Complement control module/SCR domain | 0 | Direct |
SWIB/MDM2 domain | 0 | Direct |
Spectrin repeat | 0 | Direct |
Insulin-like | 0 | Direct |
L30e-like | 0 | Direct |
SPOC domain-like | 0 | Direct |
Phosphoglucomutase, first 3 domains | 0 | Direct |
Tim10-like | 0 | Direct |
Skp1 dimerisation domain-like | 0 | Direct |
FAD-linked oxidases, C-terminal domain | 0 | Direct |
Rap/Ran-GAP | 0 | Direct |
PIN domain-like | 0 | Direct |
BEACH domain | 0 | Direct |
DEATH domain | 0 | Direct |
YWTD domain | 0 | Direct |
S-adenosylmethionine synthetase | 0 | Direct |
YbiA-like | 0 | Direct |
Single hybrid motif | 0 | Direct |
Lipovitellin-phosvitin complex, superhelical domain | 0 | Direct |
Nucleoporin domain | 0 | Direct |
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
MFPT repeat-like | 0 | Direct |
GAS2 domain-like | 0 | Direct |
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | Direct |
Terpenoid cyclases/Protein prenyltransferases | 0 | Direct |
SMAD MH1 domain | 0 | Direct |
PEP carboxykinase N-terminal domain | 0 | Direct |
Tricorn protease domain 2 | 0 | Direct |
Hormone receptor domain | 0 | Direct |
GroEL-intermediate domain like | 0 | Direct |
Sec1/munc18-like (SM) proteins | 0 | Direct |
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
Carbonic anhydrase | 0 | Direct |
Band 7/SPFH domain | 0 | Direct |
ARID-like | 0 | Direct |
Isocitrate/Isopropylmalate dehydrogenase-like | 0 | Direct |
GAT-like domain | 0 | Direct |
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
Transducin (heterotrimeric G protein), gamma chain | 0 | Direct |
alpha/beta knot | 0 | Direct |
Sec63 N-terminal domain-like | 0 | Direct |
Sec7 domain | 0 | Direct |
beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | Direct |
Phosphoenolpyruvate/pyruvate domain | 0 | Direct |
14-3-3 protein | 0 | Direct |
Nop domain | 0 | Direct |
Tubulin nucleotide-binding domain-like | 0 | Direct |
LDH C-terminal domain-like | 0 | Direct |
Carboxypeptidase regulatory domain-like | 0 | Direct |
N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
Cytochrome c | 0 | Direct |
Blood coagulation inhibitor (disintegrin) | 0 | Direct |
PAP/OAS1 substrate-binding domain | 0 | Direct |
Helical domain of Sec23/24 | 0 | Direct |
Subtilisin-like | 0 | Direct |
GroES-like | 0 | Direct |
Pepsin inhibitor-3 | 0 | Direct |
Small-conductance potassium channel | 0 | Direct |
HSP20-like chaperones | 0 | Direct |
Hypothetical protein c14orf129, hspc210 | 0 | Direct |
Integrin alpha N-terminal domain | 0 | Direct |
lambda repressor-like DNA-binding domains | 0 | Direct |
2Fe-2S ferredoxin-like | 0 | Direct |
HSP40/DnaJ peptide-binding domain | 0 | Direct |
Cdc48 domain 2-like | 0 | Direct |
Thyroglobulin type-1 domain | 0 | Direct |
Phosphoglucomutase, C-terminal domain | 0 | Direct |
PABC (PABP) domain | 0 | Direct |
Heme-dependent peroxidases | 0 | Direct |
SAICAR synthase-like | 0 | Direct |
Restriction endonuclease-like | 0 | Direct |
Chitinase insertion domain | 0 | Direct |
Clathrin adaptor appendage domain | 0 | Direct |
Ran binding protein zinc finger-like | 0 | Direct |
Cu,Zn superoxide dismutase-like | 0 | Direct |
Radical SAM enzymes | 0 | Direct |
Ribosomal protein L10-like | 0 | Direct |
Glycolipid transfer protein, GLTP | 0 | Direct |
Clc chloride channel | 0 | Direct |
DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
Tubulin C-terminal domain-like | 0 | Direct |
Smc hinge domain | 0 | Direct |
PYP-like sensor domain (PAS domain) | 0 | Direct |
Bacterial exopeptidase dimerisation domain | 0 | Direct |
Periplasmic binding protein-like II | 0 | Direct |
Chaperone J-domain | 0 | Direct |
Ribulose-phoshate binding barrel | 0 | Direct |
Annexin | 0 | Direct |
HCP-like | 0 | Direct |
Class II aaRS ABD-related | 0 | Direct |
PEBP-like | 0 | Direct |
Putative DNA-binding domain | 0 | Direct |
WWE domain | 0 | Direct |
JAB1/MPN domain | 0 | Direct |
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | Direct |
Subdomain of clathrin and coatomer appendage domain | 0 | Direct |
Pentein | 0 | Direct |
FAD-dependent thiol oxidase | 0 | Direct |
FAD-binding/transporter-associated domain-like | 0 | Direct |
Hedgehog/intein (Hint) domain | 0 | Direct |
Lamin A/C globular tail domain | 0 | Direct |
PurM C-terminal domain-like | 0 | Direct |
Ribosomal protein S10 | 0 | Direct |
Acyl-CoA dehydrogenase NM domain-like | 0 | Direct |
Intermediate filament protein, coiled coil region | 0 | Direct |
Molybdenum cofactor-binding domain | 0 | Direct |
C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
GroEL apical domain-like | 0 | Direct |
Domain of poly(ADP-ribose) polymerase | 0 | Direct |
Second domain of FERM | 0 | Direct |
Fibrinogen C-terminal domain-like | 0 | Direct |
Glutathione synthetase ATP-binding domain-like | 0 | Direct |
GYF domain | 0 | Direct |
Composite domain of metallo-dependent hydrolases | 0 | Direct |
Zn-binding ribosomal proteins | 0 | Direct |
Histone-fold | 0 | Direct |
Acid phosphatase/Vanadium-dependent haloperoxidase | 0 | Direct |
PEP carboxykinase-like | 0 | Direct |
TGS-like | 0 | Direct |
Diaminopimelate epimerase-like | 0 | Direct |
Troponin coil-coiled subunits | 0 | Direct |
MOSC N-terminal domain-like | 0 | Direct |
FF domain | 0 | Direct |
Ribokinase-like | 0 | Direct |
Polo-box domain | 0 | Direct |
ThrRS/AlaRS common domain | 0 | Direct |
Protease propeptides/inhibitors | 0 | Direct |
FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | Direct |
CO dehydrogenase ISP C-domain like | 0 | Direct |
Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | Direct |
Translational machinery components | 0 | Direct |
Invertebrate chitin-binding proteins | 0 | Direct |
Rudiment single hybrid motif | 0 | Direct |
L-aspartase-like | 0 | Direct |
DNA ligase/mRNA capping enzyme, catalytic domain | 0 | Direct |
Outer arm dynein light chain 1 | 0 | Direct |
ValRS/IleRS/LeuRS editing domain | 0 | Direct |
Cullin homology domain | 0 | Direct |
Elafin-like | 0 | Direct |
Cadherin-like | 0 | Direct |
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | Direct |
Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | Direct |
NagB/RpiA/CoA transferase-like | 0 | Direct |
P-loop containing nucleoside triphosphate hydrolases | 0.00000007798 | Direct |
PH domain-like | 0.00001907 | Direct |
PDZ domain-like | 0.008703 | Inherited |
TPR-like | 0.01221 | Inherited |
Periplasmic binding protein-like I | 0.01392 | Inherited |
ARM repeat | 0.01805 | Inherited |
ABC transporter transmembrane region | 0.01964 | Inherited |
PapD-like | 0.02301 | Inherited |
Protein kinase-like (PK-like) | 0.04522 | Inherited |
Nucleic acid-binding proteins | 0.04629 | Inherited |
Homeodomain-like | 0.05168 | Inherited |
WD40 repeat-like | 0.06117 | Inherited |
CCCH zinc finger | 0.06793 | Inherited |
FYVE/PHD zinc finger | 0.07678 | Inherited |
Translation proteins | 0.08478 | Inherited |
"Winged helix" DNA-binding domain | 0.0937 | Inherited |
Ankyrin repeat | 0.09895 | Inherited |
HLH, helix-loop-helix DNA-binding domain | 0.09914 | Inherited |
Nucleotide cyclase | 0.09914 | Inherited |
SMAD/FHA domain | 0.1059 | Inherited |
BRCT domain | 0.1059 | Inherited |
Calcium ATPase, transmembrane domain M | 0.1182 | Inherited |
SH3-domain | 0.123 | Inherited |
Metal cation-transporting ATPase, ATP-binding domain N | 0.132 | Inherited |
Regulator of G-protein signaling, RGS | 0.132 | Inherited |
EGF/Laminin | 0.1351 | Inherited |
Calcium ATPase, transduction domain A | 0.147 | Inherited |
Acid proteases | 0.147 | Inherited |
Cysteine-rich domain | 0.1548 | Inherited |
Quinoprotein alcohol dehydrogenase-like | 0.1639 | Inherited |
Multidrug efflux transporter AcrB transmembrane domain | 0.1689 | Inherited |
Cytochrome P450 | 0.1818 | Inherited |
ClpP/crotonase | 0.1826 | Inherited |
DBL homology domain (DH-domain) | 0.1826 | Inherited |
HMG-box | 0.1826 | Inherited |
E set domains | 0.186 | Inherited |
(Trans)glycosidases | 0.1925 | Inherited |
Cyclin-like | 0.2365 | Inherited |
Cysteine proteinases | 0.2428 | Inherited |
6-phosphogluconate dehydrogenase C-terminal domain-like | 0.2511 | Inherited |
Bromodomain | 0.2511 | Inherited |
Tudor/PWWP/MBT | 0.2511 | Inherited |
POZ domain | 0.2601 | Inherited |
RNA-binding domain, RBD | 0.2709 | Inherited |
Lipocalins | 0.2779 | Inherited |
SNARE-like | 0.2789 | Inherited |
Metallo-dependent phosphatases | 0.2804 | Inherited |
Cation efflux protein transmembrane domain-like | 0.343 | Inherited |
Translation proteins SH3-like domain | 0.343 | Inherited |
PX domain | 0.343 | Inherited |
HAD-like | 0.3625 | Inherited |
Nicotinic receptor ligand binding domain-like | 0.375 | Inherited |
Ubiquitin-like | 0.3922 | Inherited |
Neurotransmitter-gated ion-channel transmembrane pore | 0.4114 | Inherited |
RNI-like | 0.4179 | Inherited |
FKBP-like | 0.4192 | Inherited |
HD-domain/PDEase-like | 0.4192 | Inherited |
Class II aaRS and biotin synthetases | 0.4353 | Inherited |
DHS-like NAD/FAD-binding domain | 0.4642 | Inherited |
Myosin rod fragments | 0.4642 | Inherited |
PRTase-like | 0.4642 | Inherited |
Hect, E3 ligase catalytic domain | 0.4642 | Inherited |
Ribosomal protein S5 domain 2-like | 0.4963 | Inherited |
Galactose-binding domain-like | 0.4963 | Inherited |
Cystine-knot cytokines | 0.5003 | Inherited |
WW domain | 0.5003 | Inherited |
Sm-like ribonucleoproteins | 0.5003 | Inherited |
SH2 domain | 0.5041 | Inherited |
Calpain large subunit, middle domain (domain III) | 0.5108 | Inherited |
Riboflavin synthase domain-like | 0.5108 | Inherited |
Ferredoxin reductase-like, C-terminal NADP-linked domain | 0.5108 | Inherited |
FAD/NAD(P)-binding domain | 0.5223 | Inherited |
FAD-linked reductases, C-terminal domain | 0.5355 | Inherited |
Voltage-gated potassium channels | 0.5365 | Inherited |
SAM/Pointed domain | 0.5432 | Inherited |
Nucleotidylyl transferase | 0.5432 | Inherited |
UBC-like | 0.5454 | Inherited |
SET domain | 0.5454 | Inherited |
Seven-hairpin glycosidases | 0.5661 | Inherited |
Multidrug resistance efflux transporter EmrE | 0.5717 | Inherited |
PLP-dependent transferases | 0.5893 | Inherited |
C2 domain (Calcium/lipid-binding domain, CaLB) | 0.6053 | Inherited |
Di-copper centre-containing domain | 0.6214 | Inherited |
Nucleotide-binding domain | 0.6214 | Inherited |
KA1-like | 0.6214 | Inherited |
HIT/MYND zinc finger-like | 0.6475 | Inherited |
S-adenosyl-L-methionine-dependent methyltransferases | 0.6484 | Inherited |
MFS general substrate transporter | 0.6858 | Inherited |
4Fe-4S ferredoxins | 0.686 | Inherited |
S15/NS1 RNA-binding domain | 0.686 | Inherited |
Frizzled cysteine-rich domain | 0.686 | Inherited |
GST C-terminal domain-like | 0.6916 | Inherited |
alpha/beta-Hydrolases | 0.7487 | Inherited |
EF-hand | 0.7546 | Inherited |
ADC-like | 0.7553 | Inherited |
MIT domain | 0.7553 | Inherited |
Clavaminate synthase-like | 0.8079 | Inherited |
NAD kinase/diacylglycerol kinase-like | 0.813 | Inherited |
Cyclophilin-like | 0.8208 | Inherited |
CoA-dependent acyltransferases | 0.8208 | Inherited |
UBA-like | 0.8318 | Inherited |
SNF-like | 0.8516 | Inherited |
Leucine zipper domain | 0.857 | Inherited |
GTPase activation domain, GAP | 0.8655 | Inherited |
Thioredoxin-like | 0.895 | Inherited |
Glucocorticoid receptor-like (DNA-binding domain) | 0.9043 | Inherited |
p53-like transcription factors | 0.9044 | Inherited |
Immunoglobulin | 0.9093 | Inherited |
Ribonuclease PH domain 2-like | 0.9313 | Inherited |
DNA/RNA polymerases | 0.9349 | Inherited |
Saposin | 0.9568 | Inherited |
Ribonuclease H-like | 0.9727 | Inherited |
PAZ domain | 0.99 | Inherited |
RING/U-box | 1 | Inherited |
Nuclear receptor ligand-binding domain | 1 | Inherited |
Bet v1-like | 1 | Inherited |
B-box zinc-binding domain | 1 | Inherited |
F-box domain | 1 | Inherited |
Snake toxin-like | 1 | Inherited |
Ligand-binding domain in the NO signalling and Golgi transport | 1 | Inherited |
Family A G protein-coupled receptor-like | 1 | Inherited |
beta-beta-alpha zinc fingers | 1 | Inherited |
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Family(show details)
Family domains annotated to this WP term (Not in SDWP)
Highlighted in gray are those with FDR_all>0.001
SCOP term | FDR (all) | Annotation (direct or inherited) |
Ribosomal protein S10 | 0 | DIRECT |
Transducin (heterotrimeric G protein), gamma chain | 0 | DIRECT |
RNA-polymerase beta-prime | 0 | DIRECT |
Ubiquitin carboxyl-terminal hydrolase UCH-L | 0 | DIRECT |
Sec7 domain | 0 | DIRECT |
Carbonic anhydrase | 0 | DIRECT |
XPF/Rad1/Mus81 nuclease | 0 | DIRECT |
Serum paraoxonase/arylesterase 1, PON1 | 0 | DIRECT |
Armadillo repeat | 0 | DIRECT |
Clc chloride channel | 0 | DIRECT |
Troponin I | 0 | DIRECT |
Phosphoglucomutase, first 3 domains | 0 | DIRECT |
MutT-like | 0 | DIRECT |
Matrix metalloproteases, catalytic domain | 0 | DIRECT |
COMT-like | 0 | DIRECT |
Thiolase-related | 0 | DIRECT |
Type II chitinase | 0 | DIRECT |
N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
Sir2 family of transcriptional regulators | 0 | DIRECT |
POU-specific domain | 0 | DIRECT |
Glycosyl transferases group 1 | 0 | DIRECT |
alpha-mannosidase | 0 | DIRECT |
YihX-like | 0 | DIRECT |
Domain of poly(ADP-ribose) polymerase | 0 | DIRECT |
NTF2-like | 0 | DIRECT |
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
Protein prenyltransferases | 0 | DIRECT |
C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
Paired domain | 0 | DIRECT |
VHS domain | 0 | DIRECT |
GYF domain | 0 | DIRECT |
AMPK-beta glycogen binding domain-like | 0 | DIRECT |
U-box | 0 | DIRECT |
D-aminoacid oxidase-like | 0 | DIRECT |
ALDH-like | 0 | DIRECT |
Proprotein convertase P-domain | 0 | DIRECT |
C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
ValRS/IleRS/LeuRS editing domain | 0 | DIRECT |
Hydantoinase (dihydropyrimidinase), catalytic domain | 0 | DIRECT |
beta-Lactamase/D-ala carboxypeptidase | 0 | DIRECT |
Pumilio repeat | 0 | DIRECT |
alpha-catenin/vinculin | 0 | DIRECT |
Band 7/SPFH domain | 0 | DIRECT |
Hexokinase | 0 | DIRECT |
Oxysterol-binding protein | 0 | DIRECT |
DPP6 catalytic domain-like | 0 | DIRECT |
5' to 3' exonuclease catalytic domain | 0 | DIRECT |
Cofilin-like | 0 | DIRECT |
Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
Acetyl-CoA synthetase-like | 0 | DIRECT |
Hypothetical protein c14orf129, hspc210 | 0 | DIRECT |
CO dehydrogenase flavoprotein N-terminal domain-like | 0 | DIRECT |
Gamma-glutamyltranspeptidase-like | 0 | DIRECT |
LysM domain | 0 | DIRECT |
FYVE, a phosphatidylinositol-3-phosphate binding domain | 0 | DIRECT |
Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | DIRECT |
Chitinase insertion domain | 0 | DIRECT |
Ran binding protein zinc finger-like | 0 | DIRECT |
Brix domain | 0 | DIRECT |
Mitochondrial carrier | 0 | DIRECT |
NHL repeat | 0 | DIRECT |
Proteasome subunits | 0 | DIRECT |
Group II chaperonin (CCT, TRIC), ATPase domain | 0 | DIRECT |
Group II chaperonin (CCT, TRIC), apical domain | 0 | DIRECT |
Inositol monophosphatase/fructose-1,6-bisphosphatase-like | 0 | DIRECT |
Ribosomal protein L18 and S11 | 0 | DIRECT |
Dual specificity phosphatase-like | 0 | DIRECT |
SAM (sterile alpha motif) domain | 0 | DIRECT |
Thyroglobulin type-1 domain | 0 | DIRECT |
HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
Ribokinase-like | 0 | DIRECT |
Poly(ADP-ribose) polymerase, C-terminal domain | 0 | DIRECT |
Nucleosome core histones | 0 | DIRECT |
Actin/HSP70 | 0 | DIRECT |
HSP90 C-terminal domain | 0 | DIRECT |
Intermediate filament protein, coiled coil region | 0 | DIRECT |
Clathrin coat assembly domain | 0 | DIRECT |
SMAD MH1 domain | 0 | DIRECT |
Hsp90 middle domain | 0 | DIRECT |
GAS2 domain | 0 | DIRECT |
Lactate & malate dehydrogenases, C-terminal domain | 0 | DIRECT |
Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | DIRECT |
Spectrin repeat | 0 | DIRECT |
PurM C-terminal domain-like | 0 | DIRECT |
RecA protein-like (ATPase-domain) | 0 | DIRECT |
Second domain of FERM | 0 | DIRECT |
CoA-binding domain | 0 | DIRECT |
Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta | 0 | DIRECT |
NOL1/NOP2/sun | 0 | DIRECT |
PEP carboxykinase N-terminal domain | 0 | DIRECT |
IF2B-like | 0 | DIRECT |
Cytoplasmic domain of inward rectifier potassium channel | 0 | DIRECT |
Profilin (actin-binding protein) | 0 | DIRECT |
LEM domain | 0 | DIRECT |
Choline kinase | 0 | DIRECT |
DEP domain | 0 | DIRECT |
Double-stranded RNA-binding domain (dsRBD) | 0 | DIRECT |
Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain | 0 | DIRECT |
Citrate synthase | 0 | DIRECT |
Pancreatic carboxypeptidases | 0 | DIRECT |
Phosphatidylethanolamine binding protein | 0 | DIRECT |
BAR domain | 0 | DIRECT |
Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
Histone deacetylase, HDAC | 0 | DIRECT |
RhoGDI-like | 0 | DIRECT |
CoA transferase alpha subunit-like | 0 | DIRECT |
Phosphoribosyltransferases (PRTases) | 0 | DIRECT |
Reductases | 0 | DIRECT |
Retrovirus zinc finger-like domains | 0 | DIRECT |
beta 1,4 galactosyltransferase (b4GalT1) | 0 | DIRECT |
Insulin-like | 0 | DIRECT |
Hedgehog C-terminal (Hog) autoprocessing domain | 0 | DIRECT |
beta-sandwich domain of Sec23/24 | 0 | DIRECT |
Clathrin adaptor core protein | 0 | DIRECT |
Vertebrate phospholipase A2 | 0 | DIRECT |
TBP-associated factors, TAFs | 0 | DIRECT |
Alcohol dehydrogenase-like, N-terminal domain | 0 | DIRECT |
CUT domain | 0 | DIRECT |
Sec63 N-terminal domain | 0 | DIRECT |
DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
NLI interacting factor-like phosphatase | 0 | DIRECT |
Ferredoxin reductase FAD-binding domain-like | 0 | DIRECT |
SWIRM domain | 0 | DIRECT |
Translation initiation factor eIF4e | 0 | DIRECT |
Tetraspanin | 0 | DIRECT |
Calpain large subunit, catalytic domain (domain II) | 0 | DIRECT |
PUA domain | 0 | DIRECT |
YicI catalytic domain-like | 0 | DIRECT |
alpha-Amylases, C-terminal beta-sheet domain | 0 | DIRECT |
DNA replication initiator (cdc21/cdc54) N-terminal domain | 0 | DIRECT |
Doublecortin (DC) | 0 | DIRECT |
DNA repair protein MutS, domain III | 0 | DIRECT |
UBA domain | 0 | DIRECT |
Aquaporin-like | 0 | DIRECT |
Quinoprotein alcohol dehydrogenase-like | 0 | DIRECT |
PLC-like (P variant) | 0 | DIRECT |
Carboxypeptidase regulatory domain | 0 | DIRECT |
Myotubularin-like phosphatases | 0 | DIRECT |
acyl-CoA oxidase C-terminal domains | 0 | DIRECT |
CRAL/TRIO N-terminal domain | 0 | DIRECT |
Rap/Ran-GAP | 0 | DIRECT |
Polo-box duplicated region | 0 | DIRECT |
Integrin domains | 0 | DIRECT |
PDI-like | 0 | DIRECT |
RNA editing terminal uridyl transferase 2, RET2, domain 2 | 0 | DIRECT |
HAT/Suf repeat | 0 | DIRECT |
Regulator of chromosome condensation RCC1 | 0 | DIRECT |
Surp module (SWAP domain) | 0 | DIRECT |
Ribosomal protein S18 | 0 | DIRECT |
Phosphate binding protein-like | 0 | DIRECT |
Linker histone H1/H5 | 0 | DIRECT |
PhzC/PhzF-like | 0 | DIRECT |
Smc hinge domain | 0 | DIRECT |
Fibrinogen C-terminal domain-like | 0 | DIRECT |
Arylsulfatase | 0 | DIRECT |
SAND domain | 0 | DIRECT |
p120GAP domain-like | 0 | DIRECT |
Nucleoside diphosphate kinase, NDK | 0 | DIRECT |
HD domain | 0 | DIRECT |
Reprolysin-like | 0 | DIRECT |
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
Phosphotyrosine-binding domain (PTB) | 0 | DIRECT |
WGR domain | 0 | DIRECT |
Pyk2-associated protein beta ARF-GAP domain | 0 | DIRECT |
Calcium ATPase, transmembrane domain M | 0 | DIRECT |
MIF4G domain-like | 0 | DIRECT |
Glycogenin | 0 | DIRECT |
Glycolipid transfer protein, GLTP | 0 | DIRECT |
Pepsin inhibitor-3 | 0 | DIRECT |
L30e/L7ae ribosomal proteins | 0 | DIRECT |
Eps15 homology domain (EH domain) | 0 | DIRECT |
Cdc48 domain 2-like | 0 | DIRECT |
Heat shock protein 90, HSP90, N-terminal domain | 0 | DIRECT |
CAT-like | 0 | DIRECT |
Tubulin, GTPase domain | 0 | DIRECT |
Hydantoinase (dihydropyrimidinase) | 0 | DIRECT |
Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains | 0 | DIRECT |
Fatty acid binding protein-like | 0 | DIRECT |
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | DIRECT |
Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain | 0 | DIRECT |
FAD-dependent thiol oxidase | 0 | DIRECT |
DEATH domain, DD | 0 | DIRECT |
Annexin | 0 | DIRECT |
Class I aldolase | 0 | DIRECT |
Erythroid transcription factor GATA-1 | 0 | DIRECT |
Cadherin | 0 | DIRECT |
Lamin A/C globular tail domain | 0 | DIRECT |
Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | DIRECT |
Zn-finger domain of Sec23/24 | 0 | DIRECT |
Sec63 C-terminal domain-like | 0 | DIRECT |
Filamin repeat (rod domain) | 0 | DIRECT |
Ribosomal protein L1 | 0 | DIRECT |
D-aminoacid oxidase, N-terminal domain | 0 | DIRECT |
Peptidylglycine alpha-hydroxylating monooxygenase, PHM | 0 | DIRECT |
F1F0 ATP synthase subunit C | 0 | DIRECT |
MOSC N-terminal domain-like | 0 | DIRECT |
Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
Class II glutamine amidotransferases | 0 | DIRECT |
HEAT repeat | 0 | DIRECT |
a tRNA synthase domain | 0 | DIRECT |
DNA gyrase/MutL, N-terminal domain | 0 | DIRECT |
Nop domain | 0 | DIRECT |
Sec1/munc18-like (SM) proteins | 0 | DIRECT |
PaaI/YdiI-like | 0 | DIRECT |
5' to 3' exonuclease, C-terminal subdomain | 0 | DIRECT |
Tubulin, C-terminal domain | 0 | DIRECT |
PABC (PABP) domain | 0 | DIRECT |
Inositol polyphosphate 5-phosphatase (IPP5) | 0 | DIRECT |
Bactericidal permeability-increasing protein, BPI | 0 | DIRECT |
PDZ domain | 0 | DIRECT |
alpha-mannosidase, domain 2 | 0 | DIRECT |
Sterol carrier protein, SCP | 0 | DIRECT |
Branched-chain alpha-keto acid dehydrogenase Pyr module | 0 | DIRECT |
Elafin-like | 0 | DIRECT |
Biotinyl/lipoyl-carrier proteins and domains | 0 | DIRECT |
14-3-3 protein | 0 | DIRECT |
AN1-like Zinc finger | 0 | DIRECT |
Ngr ectodomain-like | 0 | DIRECT |
Helical domain of Sec23/24 | 0 | DIRECT |
Aminoacid dehydrogenase-like, C-terminal domain | 0 | DIRECT |
Medium chain acyl-CoA dehydrogenase-like, C-terminal domain | 0 | DIRECT |
Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | DIRECT |
Succinyl-CoA synthetase domains | 0 | DIRECT |
Internalin LRR domain | 0 | DIRECT |
Ubiquitin activating enzymes (UBA) | 0 | DIRECT |
Formate/glycerate dehydrogenases, NAD-domain | 0 | DIRECT |
GAPDH-like | 0 | DIRECT |
1,3-glucuronyltransferase | 0 | DIRECT |
Chaperone J-domain | 0 | DIRECT |
Class I glutamine amidotransferases (GAT) | 0 | DIRECT |
SCF ubiquitin ligase complex WHB domain | 0 | DIRECT |
Phoshoinositide 3-kinase (PI3K) helical domain | 0 | DIRECT |
Molybdenum cofactor-binding domain | 0 | DIRECT |
DNA gyrase/MutL, second domain | 0 | DIRECT |
PDEase | 0 | DIRECT |
ATP-dependent protease Lon (La), catalytic domain | 0 | DIRECT |
Trunk domain of Sec23/24 | 0 | DIRECT |
UDP-glucose pyrophosphorylase | 0 | DIRECT |
Biotin dependent carboxylase carboxyltransferase domain | 0 | DIRECT |
Regulator of G-protein signaling, RGS | 0 | DIRECT |
Ras-binding domain, RBD | 0 | DIRECT |
Acyl-CoA thioesterase | 0 | DIRECT |
Myeloperoxidase-like | 0 | DIRECT |
CO dehydrogenase ISP C-domain like | 0 | DIRECT |
Acireductone dioxygenase | 0 | DIRECT |
Alcohol dehydrogenase-like, C-terminal domain | 0 | DIRECT |
LacY-like proton/sugar symporter | 0 | DIRECT |
Lesion bypass DNA polymerase (Y-family), catalytic domain | 0 | DIRECT |
Pancreatic carboxypeptidase, activation domain | 0 | DIRECT |
Blood coagulation inhibitor (disintegrin) | 0 | DIRECT |
HSP20 | 0 | DIRECT |
alpha-mannosidase, C-terminal domain | 0 | DIRECT |
RNA-polymerase beta | 0 | DIRECT |
Phoshoinositide 3-kinase (PI3K), catalytic domain | 0 | DIRECT |
Skp1 dimerisation domain-like | 0 | DIRECT |
Pleckstrin-homology domain (PH domain) | 0 | DIRECT |
FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | DIRECT |
S-adenosylmethionine synthetase | 0 | DIRECT |
Branched-chain alpha-keto acid dehydrogenase PP module | 0 | DIRECT |
Transducin (alpha subunit), insertion domain | 0 | DIRECT |
HCDH C-domain-like | 0 | DIRECT |
28-residue LRR | 0 | DIRECT |
FtsH protease domain-like | 0 | DIRECT |
SWIB/MDM2 domain | 0 | DIRECT |
MFPT repeat | 0 | DIRECT |
Subtilases | 0 | DIRECT |
BC N-terminal domain-like | 0 | DIRECT |
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
MIR domain | 0 | DIRECT |
Small-conductance potassium channel | 0 | DIRECT |
Cation efflux protein cytoplasmic domain-like | 0 | DIRECT |
Arfaptin, Rac-binding fragment | 0 | DIRECT |
Lipovitellin-phosvitin complex, superhelical domain | 0 | DIRECT |
Third domain of FERM | 0 | DIRECT |
BC C-terminal domain-like | 0 | DIRECT |
YbiA-like | 0 | DIRECT |
Glycerol kinase | 0 | DIRECT |
PurM N-terminal domain-like | 0 | DIRECT |
L-aminoacid/polyamine oxidase | 0 | DIRECT |
BEACH domain | 0 | DIRECT |
BC ATP-binding domain-like | 0 | DIRECT |
DPP6 N-terminal domain-like | 0 | DIRECT |
SMAD domain | 0 | DIRECT |
Acylamino-acid-releasing enzyme, C-terminal donain | 0 | DIRECT |
Glycerophosphoryl diester phosphodiesterase | 0 | DIRECT |
WWE domain | 0 | DIRECT |
Dimeric isocitrate & isopropylmalate dehydrogenases | 0 | DIRECT |
Methionine aminopeptidase, insert domain | 0 | DIRECT |
Anticodon-binding domain | 0 | DIRECT |
Cullin homology domain | 0 | DIRECT |
Tim10/DDP | 0 | DIRECT |
Chromo domain | 0 | DIRECT |
FF domain | 0 | DIRECT |
t-snare proteins | 0 | DIRECT |
Anticodon-binding domain of Class II aaRS | 0 | DIRECT |
FHA domain | 0 | DIRECT |
Acyl-carrier protein (ACP) | 0 | DIRECT |
Arginine methyltransferase | 0 | DIRECT |
Amylase, catalytic domain | 0 | DIRECT |
PEP carboxykinase C-terminal domain | 0 | DIRECT |
First domain of FERM | 0 | DIRECT |
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | DIRECT |
Hormone receptor domain | 0 | DIRECT |
ARID domain | 0 | DIRECT |
CO dehydrogenase molybdoprotein N-domain-like | 0 | DIRECT |
La domain | 0 | DIRECT |
Adenain-like | 0 | DIRECT |
Cullin repeat | 0 | DIRECT |
Heme-dependent catalases | 0 | DIRECT |
Epoxide hydrolase | 0 | DIRECT |
Laminin G-like module | 0 | DIRECT |
2Fe-2S ferredoxin domains from multidomain proteins | 0 | DIRECT |
LDH N-terminal domain-like | 0 | DIRECT |
Inositol polyphosphate kinase (IPK) | 0 | DIRECT |
YWTD domain | 0 | DIRECT |
cAMP-binding domain | 0 | DIRECT |
Cu,Zn superoxide dismutase-like | 0 | DIRECT |
Complement control module/SCR domain | 0 | DIRECT |
Cell cycle control phosphatase, catalytic domain | 0 | DIRECT |
ets domain | 0 | DIRECT |
Group II chaperonin (CCT, TRIC), intermediate domain | 0 | DIRECT |
Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
Glutaminase | 0 | DIRECT |
Proton glutamate symport protein | 0 | DIRECT |
Mammalian PLC | 0 | DIRECT |
Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain | 0 | DIRECT |
Translational machinery components | 0 | DIRECT |
Bacterial exopeptidase dimerisation domain | 0 | DIRECT |
acyl-CoA oxidase N-terminal domains | 0 | DIRECT |
Single strand DNA-binding domain, SSB | 0 | DIRECT |
ABC transporter ATPase domain-like | 0.001183 | INHERITED FROM: metal response variant || RNAi response variant || colchicine hypersensitive || organism homeostasis metabolism variant || cadmium response variant || RNAi resistant |
Tandem AAA-ATPase domain | 0.003427 | INHERITED FROM: organism stress response variant || RNAi response variant || germline RNAi resistant || organism UV response variant || DNA damage response variant || sick || organism environmental stimulus response variant |
Homeodomain | 0.03517 | INHERITED FROM: carbon dioxide avoidance variant || ectopic expression transgene || level of transgene expression variant || organism metabolism processing variant || carbon dioxide response variant |
ABC transporter transmembrane region | 0.04123 | INHERITED FROM: metal response variant || RNAi response variant || colchicine hypersensitive || cadmium response variant || RNAi resistant |
G proteins | 0.04445 | INHERITED FROM: protein phosphorylation variant || pathogen release variant || carbon dioxide avoidance variant || osmotic integrity variant || aldicarb response variant || drug induced gene expression variant || chemosensory response variant || fat content variant || chemotaxis variant || chemosensory behavior variant || hermaphrodite physiology variant || sexually dimorphic physiology variant || organism metabolism processing variant || protein subcellular localization variant || bacterially unswollen || organism environmental stimulus response variant || carbon dioxide response variant |
WD40-repeat | 0.04457 | INHERITED FROM: osmotic avoidance variant || ivermectin resistant || ivermectin response variant || protein aggregation induced behavior variant || dauer defective || antimicrobial gene expression variant |
L-arabinose binding protein-like | 0.05603 | INHERITED FROM: cation positive chemotaxis defective || alkaline pH chemotaxis variant || magnesium chemotaxis defective || anion positive chemotaxis defective || iodide chemotaxis defective || thermosensory behavior variant || anion positive chemotaxis variant || chemosensory response variant || thermotaxis variant || cation positive chemotaxis variant || organism temperature response variant || chemotaxis variant || lithium chemotaxis defective || chemosensory behavior variant || bromide chemotaxis variant || iodide chemotaxis variant || organism environmental stimulus response variant || aqueous positive chemotaxis variant || bromide chemotaxis defective |
MSP-like | 0.06024 | INHERITED FROM: dauer metabolism variant || dauer lifespan extended || fat content variant || dauer lifespan variant || lipid metabolism variant |
Protein kinases, catalytic subunit | 0.07544 | INHERITED FROM: protein phosphorylation variant || alkaline pH chemotaxis variant || mechanosensation variant || oxygen response variant || metal response variant || chemical response variant || colchicine resistant || aldicarb response variant || drug induced gene expression variant || chemosensory response variant || pathogen induced gene expression variant || octanol chemotaxis defective || chemotaxis variant || conflicting sensory integration variant || kinase activity reduced || protein modification variant || egg laying response to food variant || chemosensory behavior variant || anoxia resistant || lipid synthesis increased || positive chemotaxis variant || protein subcellular localization variant || protein expression variant || second messenger mediated signaling variant || protein phosphorylation reduced |
CCCH zinc finger | 0.08395 | INHERITED FROM: ectopic expression transgene || gene expression variant || transgene expression variant || mRNA expression ectopic |
Canonical RBD | 0.08683 | INHERITED FROM: no induction of antimicrobial peptide expression after infection || late larval arrest || innate immune response variant || RNA expression variant || RNA processing variant || sick || mRNA export variant || organism metabolism processing variant || RNA metabolism variant || antimicrobial gene expression variant || starvation induced apoptosis variant |
Extended AAA-ATPase domain | 0.1016 | INHERITED FROM: protein expression increased || spontaneous mutation rate increased || sick |
Tetratricopeptide repeat (TPR) | 0.1103 | INHERITED FROM: organism metabolism processing variant |
Cold shock DNA-binding domain-like | 0.1254 | INHERITED FROM: nonsense mRNA accumulation || mRNA surveillance defective || sick || hermaphrodite physiology variant |
Adenylyl and guanylyl cyclase catalytic domain | 0.1298 | INHERITED FROM: cation positive chemotaxis defective || alkaline pH chemotaxis variant || magnesium chemotaxis defective || anion positive chemotaxis defective || iodide chemotaxis defective || osmotic avoidance variant || chemosensory response variant || diacetyl chemotaxis variant || cation positive chemotaxis variant || aqueous chemosensory response variant || chemotaxis variant || lithium chemotaxis defective || chemosensory behavior variant || AWC odorant chemotaxis variant || AWC odorant chemotaxis defective || positive chemotaxis variant || bromide chemotaxis variant || iodide chemotaxis variant || organism environmental stimulus response variant || bromide chemotaxis defective || second messenger mediated signaling variant || carbon dioxide response variant |
Motor proteins | 0.1298 | INHERITED FROM: sexually dimorphic mechanosensation variant |
HLH, helix-loop-helix DNA-binding domain | 0.1298 | INHERITED FROM: aqueous positive chemotaxis defective || ectopic expression transgene || RNA expression variant || pathogen resistance increased || fungal resistance increased || lysine chemotaxis defective || gene expression level reduced |
Ankyrin repeat | 0.1692 | INHERITED FROM: organism heat response variant || odorant negative chemotaxis defective || octanol chemotaxis defective || octanol chemotaxis variant |
Calcium ATPase, transduction domain A | 0.1693 | INHERITED FROM: drug hypersensitive || nicotine hypersensitive |
SH3-domain | 0.1764 | INHERITED FROM: aldicarb response variant || protein expression reduced || protein expression variant |
Class I aminoacyl-tRNA synthetases (RS), catalytic domain | 0.2064 | INHERITED FROM: oxygen response variant || paraquat resistant || transgene expression increased || innate immune response variant || paraquat response variant || gene expression variant || hypoxia response variant || hypoxia resistant || receptor mediated endocytosis defective || organism environmental stimulus response variant || antimicrobial gene expression variant |
Elongation factors | 0.2064 | INHERITED FROM: protein phosphorylation variant || mRNA levels reduced || protein phosphorylation increased || protein protein interaction variant || proteasome core activity variant || mRNA levels increased || protein aggregation variant |
Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain | 0.2064 | INHERITED FROM: oxygen response variant || gene expression variant || hypoxia response variant || hypoxia resistant || receptor mediated endocytosis defective || transgene expression variant || hermaphrodite physiology variant || sexually dimorphic physiology variant || organism metabolism processing variant || organism environmental stimulus response variant || oocyte physiology variant |
DBL homology domain (DH-domain) | 0.2064 | INHERITED FROM: pathogen resistance increased || aldicarb response variant || organism pathogen response variant || bacterially unswollen || organism environmental stimulus response variant |
Cyclin | 0.2064 | INHERITED FROM: level of transgene expression variant |
HMG-box | 0.2064 | INHERITED FROM: maintenance of gene silencing variant |
Pepsin-like | 0.2277 | INHERITED FROM: transgene subcellular localization variant || protein interaction variant || osmotic integrity variant || hypoosmotic shock hypersensitive || gene expression variant || protein protein interaction variant || transgene expression variant || pattern of transgene expression variant || organism metabolism processing variant || protein aggregation variant |
Histone lysine methyltransferases | 0.2277 | INHERITED FROM: maintenance of gene silencing variant || RNAi response variant || ectopic expression antibody || histone methylation variant || gene expression variant || mRNA expression variant || protein methylation variant || protein modification variant || shortened life span || pattern of transgene expression variant || organism metabolism processing variant || protein metabolism variant || life span variant |
Forkhead DNA-binding domain | 0.2514 | INHERITED FROM: transgene subcellular localization variant || gene expression variant || transgene expression variant || pattern of transgene expression variant || organism metabolism processing variant |
Metal cation-transporting ATPase, ATP-binding domain N | 0.2514 | INHERITED FROM: drug hypersensitive || nicotine hypersensitive || organism environmental stimulus response variant |
Multidrug efflux transporter AcrB transmembrane domain | 0.261 | INHERITED FROM: odorant chemosensory response variant || odorant positive chemotaxis defective || egg integrity defective early emb || positive chemotaxis defective || embryo osmotic integrity defective early emb |
Cytochrome P450 | 0.265 | INHERITED FROM: metal response variant || metabolite content decreased || cadmium response variant |
Bromodomain | 0.2768 | INHERITED FROM: acute functional tolerance to alcohol defective || anesthetic response variant || drug adaptation variant || ethanol resistant || organism UV response variant || gene expression variant || anesthetic resistant || sick || organism UV hypersensitive |
6-phosphogluconate dehydrogenase-like, N-terminal domain | 0.2768 | INHERITED FROM: fat content variant || lipid metabolism variant |
Acetylcholinesterase-like | 0.2842 | INHERITED FROM: acetylcholinesterase reduced || acetylcholinesterase activity variant || enzyme activity reduced || enzyme activity variant |
FAD/NAD-linked reductases, N-terminal and central domains | 0.3046 | INHERITED FROM: paraquat response variant || pesticide response variant |
Neurotransmitter-gated ion-channel transmembrane pore | 0.3177 | INHERITED FROM: mechanosensation variant || chemical response variant || slowing response on food variant || sodium chloride chemotaxis variant || nicotine resistant || thermosensory behavior variant || cholinergic agonist resistant || drug response variant || chemosensory response variant || hypoosmotic shock hypersensitive || organism temperature response variant || chemotaxis variant || antihelmintic response variant || chemosensory behavior variant || AWC odorant chemotaxis variant || positive chemotaxis variant || selenium response variant || DMPP response variant || benzaldehyde chemotaxis variant || organism environmental stimulus response variant |
Meta-cation ATPase, catalytic domain P | 0.3352 | INHERITED FROM: nicotine hypersensitive || organism environmental stimulus response variant |
Sm motif of small nuclear ribonucleoproteins, SNRNP | 0.3352 | INHERITED FROM: pattern protein expression variant || protein protein interaction variant || receptor mediated endocytosis defective || sick || hermaphrodite physiology variant || pattern of transgene expression variant || sexually dimorphic physiology variant || protein subcellular localization variant || life span variant || protein aggregation variant || oocyte physiology variant |
Crotonase-like | 0.3352 | INHERITED FROM: fat content variant || lipid metabolism variant |
PX domain | 0.3696 | INHERITED FROM: protein subcellular localization variant || protein expression variant |
GABA-aminotransferase-like | 0.4041 | INHERITED FROM: fat content reduced |
Protein kinase cysteine-rich domain (cys2, phorbol-binding domain) | 0.4254 | INHERITED FROM: drug resistant || organism stress response variant || thermosensory behavior variant || aldicarb response variant || drug induced gene expression variant || thermotaxis variant || organism temperature response variant || response to injury variant || nose touch variant || protein subcellular localization variant || antimicrobial gene expression variant || odorant positive chemotaxis variant |
BTB/POZ domain | 0.4256 | INHERITED FROM: L1 arrest || early larval arrest || protein aggregation induced behavior variant || resistant to protein aggregation induced paralysis || chemical hypersensitive |
FKBP immunophilin/proline isomerase | 0.4452 | INHERITED FROM: transgene subcellular localization variant || protein interaction variant || protein protein interaction variant || pattern of transgene expression variant || protein aggregation variant |
Cation efflux protein transmembrane domain-like | 0.4452 | INHERITED FROM: metal response variant || manganese toxicity resistant || manganese response variant || cadmium response variant || cadmium hypersensitive |
PHD domain | 0.4537 | INHERITED FROM: transgene subcellular localization variant || organism UV response variant || gene expression variant || transgene expression variant || protein methylation variant || protein modification variant || organism UV hypersensitive || organism metabolism processing variant || RNAi resistant || organism environmental stimulus response variant |
Pyridoxal-dependent decarboxylase | 0.4864 | INHERITED FROM: egg laying response to drug variant || carbon dioxide avoidance variant || carbon dioxide response variant |
Hect, E3 ligase catalytic domain | 0.4864 | INHERITED FROM: transgene subcellular localization variant || protein interaction variant || gene expression variant || protein protein interaction variant || protein aggregation induced behavior variant || transgene expression variant || cell stress response variant || pattern of transgene expression variant || organism metabolism processing variant || germ cell ionizing radiation response variant || protein aggregation variant |
Myosin rod fragments | 0.4864 | INHERITED FROM: hermaphrodite physiology variant || sexually dimorphic physiology variant |
Glutathione S-transferase (GST), N-terminal domain | 0.4896 | INHERITED FROM: organism stress response variant || metal response variant || organism electrophilic stress hypersensitive || paraquat response variant || organism heat hypersensitive || enzyme activity reduced || enzyme activity variant || organism environmental stimulus response variant || cadmium hypersensitive |
Nicotinic receptor ligand binding domain-like | 0.5135 | INHERITED FROM: mechanosensation variant || chemical response variant || slowing response on food variant || sodium chloride chemotaxis variant || nicotine resistant || thermosensory behavior variant || cholinergic agonist resistant || drug response variant || chemosensory response variant || hypoosmotic shock hypersensitive || chemotaxis variant || antihelmintic response variant || chemosensory behavior variant || AWC odorant chemotaxis variant || positive chemotaxis variant || selenium response variant || DMPP response variant || benzaldehyde chemotaxis variant || organism environmental stimulus response variant |
I set domains | 0.5143 | INHERITED FROM: aldicarb response variant || aldicarb resistant || growth rate variant || protein degradation variant |
Papain-like | 0.524 | INHERITED FROM: protein interaction variant || osmotic integrity variant || hypoosmotic shock hypersensitive || gene expression variant || protein protein interaction variant || transgene expression variant || pattern of transgene expression variant || organism metabolism processing variant || protein aggregation variant |
Calpain large subunit, middle domain (domain III) | 0.535 | INHERITED FROM: metabolic pathway variant || protein degradation variant || protein metabolism variant |
Gastric lipase | 0.535 | INHERITED FROM: fat content variant || lipid metabolism variant |
Myb/SANT domain | 0.535 | INHERITED FROM: growth rate variant |
WW domain | 0.5452 | INHERITED FROM: maintenance of gene silencing variant |
UBC-related | 0.5747 | INHERITED FROM: transgene subcellular localization variant || late larval arrest || protein interaction variant || gene expression variant || protein protein interaction variant || transgene expression variant || pattern of transgene expression variant || organism metabolism processing variant || protein aggregation variant |
Class I alpha-1;2-mannosidase, catalytic domain | 0.5833 | INHERITED FROM: extended life span || protein protein interaction variant || protein aggregation variant |
Synaptotagmin-like (S variant) | 0.6135 | INHERITED FROM: drug resistant || acetylcholinesterase inhibitor response variant || acetylcholinesterase inhibitor resistant || pattern protein expression variant || drug response variant || protein subcellular localization variant |
SH2 domain | 0.615 | INHERITED FROM: level of protein expression variant || protein expression reduced || protein expression variant |
Ubiquitin carboxyl-terminal hydrolase, UCH | 0.659 | INHERITED FROM: protein interaction variant || gene expression variant || protein protein interaction variant || transgene expression variant || pattern of transgene expression variant || organism metabolism processing variant || protein aggregation variant |
Frizzled cysteine-rich domain | 0.7002 | INHERITED FROM: antibody staining variant || transgene expression reduced |
Transforming growth factor (TGF)-beta | 0.7002 | INHERITED FROM: level of transgene expression variant || drug response variant || transgene expression reduced || nicotine response variant || levamisole response variant |
EF-hand modules in multidomain proteins | 0.7002 | INHERITED FROM: cell stress response variant || protein expression variant |
Ubiquitin-related | 0.7403 | INHERITED FROM: protein interaction variant || protein protein interaction variant || transgene expression variant || hypersensitive to protein aggregation induced paralysis || protein aggregation variant |
H-NOX domain | 0.7658 | INHERITED FROM: carbon dioxide avoidance variant || carbon dioxide response variant |
Cdc48 N-terminal domain-like | 0.7658 | INHERITED FROM: protein interaction variant || protein protein interaction variant || metabolic pathway variant || protein metabolism variant || transgene expression reduced || protein aggregation variant |
Hemocyanin middle domain | 0.7658 | INHERITED FROM: organism stress response variant || organism ionizing radiation response variant || cell stress response variant || cell ionizing radiation response variant || germ cell ionizing radiation response variant |
Bacterial lipase | 0.7658 | INHERITED FROM: fat content variant || lipid metabolism variant |
MIT domain | 0.7658 | INHERITED FROM: protein interaction variant || protein protein interaction variant || protein aggregation variant |
Voltage-gated potassium channels | 0.7843 | INHERITED FROM: serotonin response variant || serotonin resistant || adrenergic receptor antagonist response variant || growth rate variant || protein degradation variant |
AAT-like | 0.8366 | INHERITED FROM: growth rate variant |
LIM domain | 0.8366 | INHERITED FROM: level of protein expression variant || protein expression reduced || protein degradation variant |
Cyclophilin (peptidylprolyl isomerase) | 0.8579 | INHERITED FROM: transgene subcellular localization variant || protein interaction variant || protein protein interaction variant || transgene expression variant || pattern of transgene expression variant || protein aggregation variant |
DnaQ-like 3'-5' exonuclease | 0.8824 | INHERITED FROM: RNAi response variant |
Glutathione S-transferase (GST), C-terminal domain | 0.8854 | INHERITED FROM: organism stress response variant || organism electrophilic stress hypersensitive || organism heat hypersensitive || enzyme activity reduced || enzyme activity variant || cadmium hypersensitive |
Calmodulin-like | 0.8954 | INHERITED FROM: protein interaction variant || protein protein interaction variant || protein aggregation variant |
Leucine zipper domain | 0.8965 | INHERITED FROM: mRNA levels reduced || pathogen susceptibility increased || level of transgene expression variant || pore forming toxin response variant || transgene expression reduced |
SNF-like | 0.9079 | INHERITED FROM: drug hypersensitive |
Extended PAW domain | 0.9079 | INHERITED FROM: transgene subcellular localization variant || protein interaction variant || protein protein interaction variant || pattern of transgene expression variant || protein aggregation variant |
Ribonuclease PH domain 1-like | 0.9436 | INHERITED FROM: early larval arrest |
Ribonuclease PH domain 2-like | 0.9436 | INHERITED FROM: early larval arrest |
NagD-like | 0.9436 | INHERITED FROM: dauer formation variant || dauer constitutive |
Choline/Carnitine O-acyltransferase | 0.9945 | INHERITED FROM: fat content variant || lipid metabolism variant |
RING finger domain, C3HC4 | 1 | INHERITED FROM: transgene subcellular localization variant || protein interaction variant || protein protein interaction variant || pattern of transgene expression variant || organism metabolism processing variant || germ cell hypersensitive ionizing radiation || germ cell ionizing radiation response variant || protein aggregation variant |
PAZ domain | 1 | INHERITED FROM: maintenance of gene silencing variant || RNAi response variant || RNA expression variant || RNAi enhanced || 21U RNA expression variant || mRNA levels increased || siRNA expression variant |
F-box domain | 1 | INHERITED FROM: protein aggregation induced behavior variant || resistant to protein aggregation induced paralysis |
Nuclear receptor ligand-binding domain | 1 | INHERITED FROM: SDS sensitive dauer || dauer resistance to harsh conditions variant || gene expression level high || fat content increased || gene expression level reduced || transgene expression reduced |
B-box zinc-binding domain | 1 | INHERITED FROM: transgene subcellular localization variant || protein interaction variant || gene expression variant || protein protein interaction variant || transgene expression variant || protein aggregation variant |
Glutathione peroxidase-like | 1 | INHERITED FROM: paraquat response variant || pesticide response variant |
Rhodopsin-like | 1 | INHERITED FROM: egg laying response to drug variant || serotonin response variant || drug withdrawal response variant || serotonin resistant || biogenic amine receptor antagonist resistant || aqueous adaptation defective || male tail curling serotonin variant || serotonin hypersensitive || organism pathogen response variant || serotonin induced fat reduction variant || locomotion rate serotonin variant || serotonin induced pumping variant |
N-acetyl transferase, NAT | 1 | INHERITED FROM: ectopic expression transgene |
Nuclear receptor | 1 | INHERITED FROM: SDS sensitive dauer || dauer resistance to harsh conditions variant || gene expression level high || fat content increased || gene expression level reduced || transgene expression reduced |
SCOP term | FDR (all) | Annotation (direct or inherited) |
Ribosomal protein S10 | 0 | Direct |
Transducin (heterotrimeric G protein), gamma chain | 0 | Direct |
RNA-polymerase beta-prime | 0 | Direct |
Ubiquitin carboxyl-terminal hydrolase UCH-L | 0 | Direct |
Sec7 domain | 0 | Direct |
Carbonic anhydrase | 0 | Direct |
XPF/Rad1/Mus81 nuclease | 0 | Direct |
Serum paraoxonase/arylesterase 1, PON1 | 0 | Direct |
Armadillo repeat | 0 | Direct |
Clc chloride channel | 0 | Direct |
Troponin I | 0 | Direct |
Phosphoglucomutase, first 3 domains | 0 | Direct |
MutT-like | 0 | Direct |
Matrix metalloproteases, catalytic domain | 0 | Direct |
COMT-like | 0 | Direct |
Thiolase-related | 0 | Direct |
Type II chitinase | 0 | Direct |
N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
Sir2 family of transcriptional regulators | 0 | Direct |
POU-specific domain | 0 | Direct |
Glycosyl transferases group 1 | 0 | Direct |
alpha-mannosidase | 0 | Direct |
YihX-like | 0 | Direct |
Domain of poly(ADP-ribose) polymerase | 0 | Direct |
NTF2-like | 0 | Direct |
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
Protein prenyltransferases | 0 | Direct |
C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
Paired domain | 0 | Direct |
VHS domain | 0 | Direct |
GYF domain | 0 | Direct |
AMPK-beta glycogen binding domain-like | 0 | Direct |
U-box | 0 | Direct |
D-aminoacid oxidase-like | 0 | Direct |
ALDH-like | 0 | Direct |
Proprotein convertase P-domain | 0 | Direct |
C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
ValRS/IleRS/LeuRS editing domain | 0 | Direct |
Hydantoinase (dihydropyrimidinase), catalytic domain | 0 | Direct |
beta-Lactamase/D-ala carboxypeptidase | 0 | Direct |
Pumilio repeat | 0 | Direct |
alpha-catenin/vinculin | 0 | Direct |
Band 7/SPFH domain | 0 | Direct |
Hexokinase | 0 | Direct |
Oxysterol-binding protein | 0 | Direct |
DPP6 catalytic domain-like | 0 | Direct |
5' to 3' exonuclease catalytic domain | 0 | Direct |
Cofilin-like | 0 | Direct |
Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
Acetyl-CoA synthetase-like | 0 | Direct |
Hypothetical protein c14orf129, hspc210 | 0 | Direct |
CO dehydrogenase flavoprotein N-terminal domain-like | 0 | Direct |
Gamma-glutamyltranspeptidase-like | 0 | Direct |
LysM domain | 0 | Direct |
FYVE, a phosphatidylinositol-3-phosphate binding domain | 0 | Direct |
Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | Direct |
Chitinase insertion domain | 0 | Direct |
Ran binding protein zinc finger-like | 0 | Direct |
Brix domain | 0 | Direct |
Mitochondrial carrier | 0 | Direct |
NHL repeat | 0 | Direct |
Proteasome subunits | 0 | Direct |
Group II chaperonin (CCT, TRIC), ATPase domain | 0 | Direct |
Group II chaperonin (CCT, TRIC), apical domain | 0 | Direct |
Inositol monophosphatase/fructose-1,6-bisphosphatase-like | 0 | Direct |
Ribosomal protein L18 and S11 | 0 | Direct |
Dual specificity phosphatase-like | 0 | Direct |
SAM (sterile alpha motif) domain | 0 | Direct |
Thyroglobulin type-1 domain | 0 | Direct |
HSP40/DnaJ peptide-binding domain | 0 | Direct |
Ribokinase-like | 0 | Direct |
Poly(ADP-ribose) polymerase, C-terminal domain | 0 | Direct |
Nucleosome core histones | 0 | Direct |
Actin/HSP70 | 0 | Direct |
HSP90 C-terminal domain | 0 | Direct |
Intermediate filament protein, coiled coil region | 0 | Direct |
Clathrin coat assembly domain | 0 | Direct |
SMAD MH1 domain | 0 | Direct |
Hsp90 middle domain | 0 | Direct |
GAS2 domain | 0 | Direct |
Lactate & malate dehydrogenases, C-terminal domain | 0 | Direct |
Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | Direct |
Spectrin repeat | 0 | Direct |
PurM C-terminal domain-like | 0 | Direct |
RecA protein-like (ATPase-domain) | 0 | Direct |
Second domain of FERM | 0 | Direct |
CoA-binding domain | 0 | Direct |
Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta | 0 | Direct |
NOL1/NOP2/sun | 0 | Direct |
PEP carboxykinase N-terminal domain | 0 | Direct |
IF2B-like | 0 | Direct |
Cytoplasmic domain of inward rectifier potassium channel | 0 | Direct |
Profilin (actin-binding protein) | 0 | Direct |
LEM domain | 0 | Direct |
Choline kinase | 0 | Direct |
DEP domain | 0 | Direct |
Double-stranded RNA-binding domain (dsRBD) | 0 | Direct |
Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain | 0 | Direct |
Citrate synthase | 0 | Direct |
Pancreatic carboxypeptidases | 0 | Direct |
Phosphatidylethanolamine binding protein | 0 | Direct |
BAR domain | 0 | Direct |
Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
Histone deacetylase, HDAC | 0 | Direct |
RhoGDI-like | 0 | Direct |
CoA transferase alpha subunit-like | 0 | Direct |
Phosphoribosyltransferases (PRTases) | 0 | Direct |
Reductases | 0 | Direct |
Retrovirus zinc finger-like domains | 0 | Direct |
beta 1,4 galactosyltransferase (b4GalT1) | 0 | Direct |
Insulin-like | 0 | Direct |
Hedgehog C-terminal (Hog) autoprocessing domain | 0 | Direct |
beta-sandwich domain of Sec23/24 | 0 | Direct |
Clathrin adaptor core protein | 0 | Direct |
Vertebrate phospholipase A2 | 0 | Direct |
TBP-associated factors, TAFs | 0 | Direct |
Alcohol dehydrogenase-like, N-terminal domain | 0 | Direct |
CUT domain | 0 | Direct |
Sec63 N-terminal domain | 0 | Direct |
DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
NLI interacting factor-like phosphatase | 0 | Direct |
Ferredoxin reductase FAD-binding domain-like | 0 | Direct |
SWIRM domain | 0 | Direct |
Translation initiation factor eIF4e | 0 | Direct |
Tetraspanin | 0 | Direct |
Calpain large subunit, catalytic domain (domain II) | 0 | Direct |
PUA domain | 0 | Direct |
YicI catalytic domain-like | 0 | Direct |
alpha-Amylases, C-terminal beta-sheet domain | 0 | Direct |
DNA replication initiator (cdc21/cdc54) N-terminal domain | 0 | Direct |
Doublecortin (DC) | 0 | Direct |
DNA repair protein MutS, domain III | 0 | Direct |
UBA domain | 0 | Direct |
Aquaporin-like | 0 | Direct |
Quinoprotein alcohol dehydrogenase-like | 0 | Direct |
PLC-like (P variant) | 0 | Direct |
Carboxypeptidase regulatory domain | 0 | Direct |
Myotubularin-like phosphatases | 0 | Direct |
acyl-CoA oxidase C-terminal domains | 0 | Direct |
CRAL/TRIO N-terminal domain | 0 | Direct |
Rap/Ran-GAP | 0 | Direct |
Polo-box duplicated region | 0 | Direct |
Integrin domains | 0 | Direct |
PDI-like | 0 | Direct |
RNA editing terminal uridyl transferase 2, RET2, domain 2 | 0 | Direct |
HAT/Suf repeat | 0 | Direct |
Regulator of chromosome condensation RCC1 | 0 | Direct |
Surp module (SWAP domain) | 0 | Direct |
Ribosomal protein S18 | 0 | Direct |
Phosphate binding protein-like | 0 | Direct |
Linker histone H1/H5 | 0 | Direct |
PhzC/PhzF-like | 0 | Direct |
Smc hinge domain | 0 | Direct |
Fibrinogen C-terminal domain-like | 0 | Direct |
Arylsulfatase | 0 | Direct |
SAND domain | 0 | Direct |
p120GAP domain-like | 0 | Direct |
Nucleoside diphosphate kinase, NDK | 0 | Direct |
HD domain | 0 | Direct |
Reprolysin-like | 0 | Direct |
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
Phosphotyrosine-binding domain (PTB) | 0 | Direct |
WGR domain | 0 | Direct |
Pyk2-associated protein beta ARF-GAP domain | 0 | Direct |
Calcium ATPase, transmembrane domain M | 0 | Direct |
MIF4G domain-like | 0 | Direct |
Glycogenin | 0 | Direct |
Glycolipid transfer protein, GLTP | 0 | Direct |
Pepsin inhibitor-3 | 0 | Direct |
L30e/L7ae ribosomal proteins | 0 | Direct |
Eps15 homology domain (EH domain) | 0 | Direct |
Cdc48 domain 2-like | 0 | Direct |
Heat shock protein 90, HSP90, N-terminal domain | 0 | Direct |
CAT-like | 0 | Direct |
Tubulin, GTPase domain | 0 | Direct |
Hydantoinase (dihydropyrimidinase) | 0 | Direct |
Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains | 0 | Direct |
Fatty acid binding protein-like | 0 | Direct |
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | Direct |
Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain | 0 | Direct |
FAD-dependent thiol oxidase | 0 | Direct |
DEATH domain, DD | 0 | Direct |
Annexin | 0 | Direct |
Class I aldolase | 0 | Direct |
Erythroid transcription factor GATA-1 | 0 | Direct |
Cadherin | 0 | Direct |
Lamin A/C globular tail domain | 0 | Direct |
Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | Direct |
Zn-finger domain of Sec23/24 | 0 | Direct |
Sec63 C-terminal domain-like | 0 | Direct |
Filamin repeat (rod domain) | 0 | Direct |
Ribosomal protein L1 | 0 | Direct |
D-aminoacid oxidase, N-terminal domain | 0 | Direct |
Peptidylglycine alpha-hydroxylating monooxygenase, PHM | 0 | Direct |
F1F0 ATP synthase subunit C | 0 | Direct |
MOSC N-terminal domain-like | 0 | Direct |
Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
Class II glutamine amidotransferases | 0 | Direct |
HEAT repeat | 0 | Direct |
a tRNA synthase domain | 0 | Direct |
DNA gyrase/MutL, N-terminal domain | 0 | Direct |
Nop domain | 0 | Direct |
Sec1/munc18-like (SM) proteins | 0 | Direct |
PaaI/YdiI-like | 0 | Direct |
5' to 3' exonuclease, C-terminal subdomain | 0 | Direct |
Tubulin, C-terminal domain | 0 | Direct |
PABC (PABP) domain | 0 | Direct |
Inositol polyphosphate 5-phosphatase (IPP5) | 0 | Direct |
Bactericidal permeability-increasing protein, BPI | 0 | Direct |
PDZ domain | 0 | Direct |
alpha-mannosidase, domain 2 | 0 | Direct |
Sterol carrier protein, SCP | 0 | Direct |
Branched-chain alpha-keto acid dehydrogenase Pyr module | 0 | Direct |
Elafin-like | 0 | Direct |
Biotinyl/lipoyl-carrier proteins and domains | 0 | Direct |
14-3-3 protein | 0 | Direct |
AN1-like Zinc finger | 0 | Direct |
Ngr ectodomain-like | 0 | Direct |
Helical domain of Sec23/24 | 0 | Direct |
Aminoacid dehydrogenase-like, C-terminal domain | 0 | Direct |
Medium chain acyl-CoA dehydrogenase-like, C-terminal domain | 0 | Direct |
Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | Direct |
Succinyl-CoA synthetase domains | 0 | Direct |
Internalin LRR domain | 0 | Direct |
Ubiquitin activating enzymes (UBA) | 0 | Direct |
Formate/glycerate dehydrogenases, NAD-domain | 0 | Direct |
GAPDH-like | 0 | Direct |
1,3-glucuronyltransferase | 0 | Direct |
Chaperone J-domain | 0 | Direct |
Class I glutamine amidotransferases (GAT) | 0 | Direct |
SCF ubiquitin ligase complex WHB domain | 0 | Direct |
Phoshoinositide 3-kinase (PI3K) helical domain | 0 | Direct |
Molybdenum cofactor-binding domain | 0 | Direct |
DNA gyrase/MutL, second domain | 0 | Direct |
PDEase | 0 | Direct |
ATP-dependent protease Lon (La), catalytic domain | 0 | Direct |
Trunk domain of Sec23/24 | 0 | Direct |
UDP-glucose pyrophosphorylase | 0 | Direct |
Biotin dependent carboxylase carboxyltransferase domain | 0 | Direct |
Regulator of G-protein signaling, RGS | 0 | Direct |
Ras-binding domain, RBD | 0 | Direct |
Acyl-CoA thioesterase | 0 | Direct |
Myeloperoxidase-like | 0 | Direct |
CO dehydrogenase ISP C-domain like | 0 | Direct |
Acireductone dioxygenase | 0 | Direct |
Alcohol dehydrogenase-like, C-terminal domain | 0 | Direct |
LacY-like proton/sugar symporter | 0 | Direct |
Lesion bypass DNA polymerase (Y-family), catalytic domain | 0 | Direct |
Pancreatic carboxypeptidase, activation domain | 0 | Direct |
Blood coagulation inhibitor (disintegrin) | 0 | Direct |
HSP20 | 0 | Direct |
alpha-mannosidase, C-terminal domain | 0 | Direct |
RNA-polymerase beta | 0 | Direct |
Phoshoinositide 3-kinase (PI3K), catalytic domain | 0 | Direct |
Skp1 dimerisation domain-like | 0 | Direct |
Pleckstrin-homology domain (PH domain) | 0 | Direct |
FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | Direct |
S-adenosylmethionine synthetase | 0 | Direct |
Branched-chain alpha-keto acid dehydrogenase PP module | 0 | Direct |
Transducin (alpha subunit), insertion domain | 0 | Direct |
HCDH C-domain-like | 0 | Direct |
28-residue LRR | 0 | Direct |
FtsH protease domain-like | 0 | Direct |
SWIB/MDM2 domain | 0 | Direct |
MFPT repeat | 0 | Direct |
Subtilases | 0 | Direct |
BC N-terminal domain-like | 0 | Direct |
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
MIR domain | 0 | Direct |
Small-conductance potassium channel | 0 | Direct |
Cation efflux protein cytoplasmic domain-like | 0 | Direct |
Arfaptin, Rac-binding fragment | 0 | Direct |
Lipovitellin-phosvitin complex, superhelical domain | 0 | Direct |
Third domain of FERM | 0 | Direct |
BC C-terminal domain-like | 0 | Direct |
YbiA-like | 0 | Direct |
Glycerol kinase | 0 | Direct |
PurM N-terminal domain-like | 0 | Direct |
L-aminoacid/polyamine oxidase | 0 | Direct |
BEACH domain | 0 | Direct |
BC ATP-binding domain-like | 0 | Direct |
DPP6 N-terminal domain-like | 0 | Direct |
SMAD domain | 0 | Direct |
Acylamino-acid-releasing enzyme, C-terminal donain | 0 | Direct |
Glycerophosphoryl diester phosphodiesterase | 0 | Direct |
WWE domain | 0 | Direct |
Dimeric isocitrate & isopropylmalate dehydrogenases | 0 | Direct |
Methionine aminopeptidase, insert domain | 0 | Direct |
Anticodon-binding domain | 0 | Direct |
Cullin homology domain | 0 | Direct |
Tim10/DDP | 0 | Direct |
Chromo domain | 0 | Direct |
FF domain | 0 | Direct |
t-snare proteins | 0 | Direct |
Anticodon-binding domain of Class II aaRS | 0 | Direct |
FHA domain | 0 | Direct |
Acyl-carrier protein (ACP) | 0 | Direct |
Arginine methyltransferase | 0 | Direct |
Amylase, catalytic domain | 0 | Direct |
PEP carboxykinase C-terminal domain | 0 | Direct |
First domain of FERM | 0 | Direct |
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | Direct |
Hormone receptor domain | 0 | Direct |
ARID domain | 0 | Direct |
CO dehydrogenase molybdoprotein N-domain-like | 0 | Direct |
La domain | 0 | Direct |
Adenain-like | 0 | Direct |
Cullin repeat | 0 | Direct |
Heme-dependent catalases | 0 | Direct |
Epoxide hydrolase | 0 | Direct |
Laminin G-like module | 0 | Direct |
2Fe-2S ferredoxin domains from multidomain proteins | 0 | Direct |
LDH N-terminal domain-like | 0 | Direct |
Inositol polyphosphate kinase (IPK) | 0 | Direct |
YWTD domain | 0 | Direct |
cAMP-binding domain | 0 | Direct |
Cu,Zn superoxide dismutase-like | 0 | Direct |
Complement control module/SCR domain | 0 | Direct |
Cell cycle control phosphatase, catalytic domain | 0 | Direct |
ets domain | 0 | Direct |
Group II chaperonin (CCT, TRIC), intermediate domain | 0 | Direct |
Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
Glutaminase | 0 | Direct |
Proton glutamate symport protein | 0 | Direct |
Mammalian PLC | 0 | Direct |
Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain | 0 | Direct |
Translational machinery components | 0 | Direct |
Bacterial exopeptidase dimerisation domain | 0 | Direct |
acyl-CoA oxidase N-terminal domains | 0 | Direct |
Single strand DNA-binding domain, SSB | 0 | Direct |
ABC transporter ATPase domain-like | 0.001183 | Inherited |
Tandem AAA-ATPase domain | 0.003427 | Inherited |
Homeodomain | 0.03517 | Inherited |
ABC transporter transmembrane region | 0.04123 | Inherited |
G proteins | 0.04445 | Inherited |
WD40-repeat | 0.04457 | Inherited |
L-arabinose binding protein-like | 0.05603 | Inherited |
MSP-like | 0.06024 | Inherited |
Protein kinases, catalytic subunit | 0.07544 | Inherited |
CCCH zinc finger | 0.08395 | Inherited |
Canonical RBD | 0.08683 | Inherited |
Extended AAA-ATPase domain | 0.1016 | Inherited |
Tetratricopeptide repeat (TPR) | 0.1103 | Inherited |
Cold shock DNA-binding domain-like | 0.1254 | Inherited |
Adenylyl and guanylyl cyclase catalytic domain | 0.1298 | Inherited |
Motor proteins | 0.1298 | Inherited |
HLH, helix-loop-helix DNA-binding domain | 0.1298 | Inherited |
Ankyrin repeat | 0.1692 | Inherited |
Calcium ATPase, transduction domain A | 0.1693 | Inherited |
SH3-domain | 0.1764 | Inherited |
Class I aminoacyl-tRNA synthetases (RS), catalytic domain | 0.2064 | Inherited |
Elongation factors | 0.2064 | Inherited |
Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain | 0.2064 | Inherited |
DBL homology domain (DH-domain) | 0.2064 | Inherited |
Cyclin | 0.2064 | Inherited |
HMG-box | 0.2064 | Inherited |
Pepsin-like | 0.2277 | Inherited |
Histone lysine methyltransferases | 0.2277 | Inherited |
Forkhead DNA-binding domain | 0.2514 | Inherited |
Metal cation-transporting ATPase, ATP-binding domain N | 0.2514 | Inherited |
Multidrug efflux transporter AcrB transmembrane domain | 0.261 | Inherited |
Cytochrome P450 | 0.265 | Inherited |
Bromodomain | 0.2768 | Inherited |
6-phosphogluconate dehydrogenase-like, N-terminal domain | 0.2768 | Inherited |
Acetylcholinesterase-like | 0.2842 | Inherited |
FAD/NAD-linked reductases, N-terminal and central domains | 0.3046 | Inherited |
Neurotransmitter-gated ion-channel transmembrane pore | 0.3177 | Inherited |
Meta-cation ATPase, catalytic domain P | 0.3352 | Inherited |
Sm motif of small nuclear ribonucleoproteins, SNRNP | 0.3352 | Inherited |
Crotonase-like | 0.3352 | Inherited |
PX domain | 0.3696 | Inherited |
GABA-aminotransferase-like | 0.4041 | Inherited |
Protein kinase cysteine-rich domain (cys2, phorbol-binding domain) | 0.4254 | Inherited |
BTB/POZ domain | 0.4256 | Inherited |
FKBP immunophilin/proline isomerase | 0.4452 | Inherited |
Cation efflux protein transmembrane domain-like | 0.4452 | Inherited |
PHD domain | 0.4537 | Inherited |
Pyridoxal-dependent decarboxylase | 0.4864 | Inherited |
Hect, E3 ligase catalytic domain | 0.4864 | Inherited |
Myosin rod fragments | 0.4864 | Inherited |
Glutathione S-transferase (GST), N-terminal domain | 0.4896 | Inherited |
Nicotinic receptor ligand binding domain-like | 0.5135 | Inherited |
I set domains | 0.5143 | Inherited |
Papain-like | 0.524 | Inherited |
Calpain large subunit, middle domain (domain III) | 0.535 | Inherited |
Gastric lipase | 0.535 | Inherited |
Myb/SANT domain | 0.535 | Inherited |
WW domain | 0.5452 | Inherited |
UBC-related | 0.5747 | Inherited |
Class I alpha-1;2-mannosidase, catalytic domain | 0.5833 | Inherited |
Synaptotagmin-like (S variant) | 0.6135 | Inherited |
SH2 domain | 0.615 | Inherited |
Ubiquitin carboxyl-terminal hydrolase, UCH | 0.659 | Inherited |
Frizzled cysteine-rich domain | 0.7002 | Inherited |
Transforming growth factor (TGF)-beta | 0.7002 | Inherited |
EF-hand modules in multidomain proteins | 0.7002 | Inherited |
Ubiquitin-related | 0.7403 | Inherited |
H-NOX domain | 0.7658 | Inherited |
Cdc48 N-terminal domain-like | 0.7658 | Inherited |
Hemocyanin middle domain | 0.7658 | Inherited |
Bacterial lipase | 0.7658 | Inherited |
MIT domain | 0.7658 | Inherited |
Voltage-gated potassium channels | 0.7843 | Inherited |
AAT-like | 0.8366 | Inherited |
LIM domain | 0.8366 | Inherited |
Cyclophilin (peptidylprolyl isomerase) | 0.8579 | Inherited |
DnaQ-like 3'-5' exonuclease | 0.8824 | Inherited |
Glutathione S-transferase (GST), C-terminal domain | 0.8854 | Inherited |
Calmodulin-like | 0.8954 | Inherited |
Leucine zipper domain | 0.8965 | Inherited |
SNF-like | 0.9079 | Inherited |
Extended PAW domain | 0.9079 | Inherited |
Ribonuclease PH domain 1-like | 0.9436 | Inherited |
Ribonuclease PH domain 2-like | 0.9436 | Inherited |
NagD-like | 0.9436 | Inherited |
Choline/Carnitine O-acyltransferase | 0.9945 | Inherited |
RING finger domain, C3HC4 | 1 | Inherited |
PAZ domain | 1 | Inherited |
F-box domain | 1 | Inherited |
Nuclear receptor ligand-binding domain | 1 | Inherited |
B-box zinc-binding domain | 1 | Inherited |
Glutathione peroxidase-like | 1 | Inherited |
Rhodopsin-like | 1 | Inherited |
N-acetyl transferase, NAT | 1 | Inherited |
Nuclear receptor | 1 | Inherited |
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A presence/absence matrix is generated using protein domain
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Supra-domain (including individual superfamily)
(show details)
Supra-domains annotated to this WP term (Not in SPWP)
Highlighted in gray are those with FDR>0.001
Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
Radical SAM enzymes | 0 | DIRECT |
Nop domain | 0 | DIRECT |
Cadherin-like | 0 | DIRECT |
Cullin repeat-like | 0 | DIRECT |
5' to 3' exonuclease, C-terminal subdomain | 0 | DIRECT |
Acyl-CoA dehydrogenase NM domain-like | 0 | DIRECT |
SMAD MH1 domain | 0 | DIRECT |
Lamin A/C globular tail domain | 0 | DIRECT |
AN1-like Zinc finger | 0 | DIRECT |
Spectrin repeat | 0 | DIRECT |
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | DIRECT |
Hormone receptor domain | 0 | DIRECT |
ACP-like | 0 | DIRECT |
PEP carboxykinase N-terminal domain | 0 | DIRECT |
FF domain | 0 | DIRECT |
HCP-like | 0 | DIRECT |
Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | DIRECT |
C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
WWE domain | 0 | DIRECT |
Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
alpha-catenin/vinculin-like | 0 | DIRECT |
Nucleoside diphosphate kinase, NDK | 0 | DIRECT |
Helical domain of Sec23/24 | 0 | DIRECT |
Zn-binding ribosomal proteins | 0 | DIRECT |
Tricorn protease domain 2 | 0 | DIRECT |
DEATH domain | 0 | DIRECT |
Subdomain of clathrin and coatomer appendage domain | 0 | DIRECT |
Galactose mutarotase-like | 0 | DIRECT |
PUA domain-like | 0 | DIRECT |
Phosphoenolpyruvate/pyruvate domain | 0 | DIRECT |
Ribokinase-like | 0 | DIRECT |
Band 7/SPFH domain | 0 | DIRECT |
GroEL apical domain-like | 0 | DIRECT |
Surp module (SWAP domain) | 0 | DIRECT |
Cdc48 domain 2-like | 0 | DIRECT |
Ribulose-phoshate binding barrel | 0 | DIRECT |
ArfGap/RecO-like zinc finger | 0 | DIRECT |
MIR domain | 0 | DIRECT |
CAD & PB1 domains | 0 | DIRECT |
Hedgehog/intein (Hint) domain | 0 | DIRECT |
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
Glutathione synthetase ATP-binding domain-like | 0 | DIRECT |
TK C-terminal domain-like | 0 | DIRECT |
FAD-dependent thiol oxidase | 0 | DIRECT |
ADP-ribosylation | 0 | DIRECT |
LDH C-terminal domain-like | 0 | DIRECT |
Insulin-like | 0 | DIRECT |
Single hybrid motif | 0 | DIRECT |
Galactose oxidase, central domain | 0 | DIRECT |
Ribosomal protein L1 | 0 | DIRECT |
PGBD-like | 0 | DIRECT |
Second domain of FERM | 0 | DIRECT |
MgtE membrane domain-like | 0 | DIRECT |
Ribosomal protein S10 | 0 | DIRECT |
Phosphoglucomutase, first 3 domains | 0 | DIRECT |
Ferritin-like | 0 | DIRECT |
Tubby C-terminal domain-like | 0 | DIRECT |
Restriction endonuclease-like | 0 | DIRECT |
SWIB/MDM2 domain | 0 | DIRECT |
Chromo domain-like | 0 | DIRECT |
Cu,Zn superoxide dismutase-like | 0 | DIRECT |
Chitinase insertion domain | 0 | DIRECT |
Zn-finger domain of Sec23/24 | 0 | DIRECT |
Oxysterol-binding protein-like | 0 | DIRECT |
PYP-like sensor domain (PAS domain) | 0 | DIRECT |
t-snare proteins | 0 | DIRECT |
N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
DNA ligase/mRNA capping enzyme, catalytic domain | 0 | DIRECT |
MOSC N-terminal domain-like | 0 | DIRECT |
PHM/PNGase F | 0 | DIRECT |
PABC (PABP) domain | 0 | DIRECT |
Clc chloride channel | 0 | DIRECT |
Phoshotransferase/anion transport protein | 0 | DIRECT |
SAND domain-like | 0 | DIRECT |
GroES-like | 0 | DIRECT |
Families 57/38 glycoside transferase middle domain | 0 | DIRECT |
Ran binding protein zinc finger-like | 0 | DIRECT |
JAB1/MPN domain | 0 | DIRECT |
Clathrin adaptor appendage domain | 0 | DIRECT |
ENTH/VHS domain | 0 | DIRECT |
FtsH protease domain-like | 0 | DIRECT |
ALDH-like | 0 | DIRECT |
Histone-fold | 0 | DIRECT |
PurM N-terminal domain-like | 0 | DIRECT |
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | DIRECT |
HSP90 C-terminal domain | 0 | DIRECT |
DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
LysM domain | 0 | DIRECT |
Acetyl-CoA synthetase-like | 0 | DIRECT |
PreATP-grasp domain | 0 | DIRECT |
Cullin homology domain | 0 | DIRECT |
HSP20-like chaperones | 0 | DIRECT |
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
Thyroglobulin type-1 domain | 0 | DIRECT |
Domain of poly(ADP-ribose) polymerase | 0 | DIRECT |
Integrin alpha N-terminal domain | 0 | DIRECT |
ThrRS/AlaRS common domain | 0 | DIRECT |
DNA repair protein MutS, domain III | 0 | DIRECT |
beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | DIRECT |
Polo-box domain | 0 | DIRECT |
Class I glutamine amidotransferase-like | 0 | DIRECT |
MFPT repeat-like | 0 | DIRECT |
Tubulin C-terminal domain-like | 0 | DIRECT |
Troponin coil-coiled subunits | 0 | DIRECT |
Sec7 domain | 0 | DIRECT |
NagB/RpiA/CoA transferase-like | 0 | DIRECT |
Pepsin inhibitor-3 | 0 | DIRECT |
cAMP-binding domain-like | 0 | DIRECT |
PK beta-barrel domain-like | 0 | DIRECT |
ValRS/IleRS/LeuRS editing domain | 0 | DIRECT |
Cystatin/monellin | 0 | DIRECT |
Molybdenum cofactor-binding domain | 0 | DIRECT |
GAT-like domain | 0 | DIRECT |
F1F0 ATP synthase subunit C | 0 | DIRECT |
R3H domain | 0 | DIRECT |
eIF4e-like | 0 | DIRECT |
Thiolase-like | 0 | DIRECT |
Ribosomal L27 protein-like | 0 | DIRECT |
S-adenosylmethionine synthetase | 0 | DIRECT |
Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | DIRECT |
Ribosomal protein L10-like | 0 | DIRECT |
C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
Ribosomal proteins S24e, L23 and L15e | 0 | DIRECT |
Smc hinge domain | 0 | DIRECT |
Kringle-like | 0 | DIRECT |
L30e-like | 0 | DIRECT |
Skp1 dimerisation domain-like | 0 | DIRECT |
3-carboxy-cis,cis-mucoante lactonizing enzyme | 0 | DIRECT |
Ribosomal protein S18 | 0 | DIRECT |
Doublecortin (DC) | 0 | DIRECT |
Profilin (actin-binding protein) | 0 | DIRECT |
Rap/Ran-GAP | 0 | DIRECT |
Heme-dependent peroxidases | 0 | DIRECT |
Invertebrate chitin-binding proteins | 0 | DIRECT |
Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
CBD9-like | 0 | DIRECT |
GYF domain | 0 | DIRECT |
Actin-like ATPase domain | 0 | DIRECT |
Transducin (heterotrimeric G protein), gamma chain | 0 | DIRECT |
Diaminopimelate epimerase-like | 0 | DIRECT |
Transducin (alpha subunit), insertion domain | 0 | DIRECT |
SAICAR synthase-like | 0 | DIRECT |
Nucleoporin domain | 0 | DIRECT |
Terpenoid cyclases/Protein prenyltransferases | 0 | DIRECT |
PEP carboxykinase-like | 0 | DIRECT |
Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
Hypothetical protein c14orf129, hspc210 | 0 | DIRECT |
N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0 | DIRECT |
Aldolase | 0 | DIRECT |
Isocitrate/Isopropylmalate dehydrogenase-like | 0 | DIRECT |
Mitochondrial carrier | 0 | DIRECT |
Rudiment single hybrid motif | 0 | DIRECT |
YWTD domain | 0 | DIRECT |
dsRNA-binding domain-like | 0 | DIRECT |
RBP11-like subunits of RNA polymerase | 0 | DIRECT |
Protease propeptides/inhibitors | 0 | DIRECT |
SCP-like | 0 | DIRECT |
YbiA-like | 0 | DIRECT |
Citrate synthase | 0 | DIRECT |
GroEL equatorial domain-like | 0 | DIRECT |
CO dehydrogenase molybdoprotein N-domain-like | 0 | DIRECT |
Intermediate filament protein, coiled coil region | 0 | DIRECT |
PIN domain-like | 0 | DIRECT |
PurM C-terminal domain-like | 0 | DIRECT |
SPOC domain-like | 0 | DIRECT |
Activating enzymes of the ubiquitin-like proteins | 0 | DIRECT |
Blood coagulation inhibitor (disintegrin) | 0 | DIRECT |
CRAL/TRIO N-terminal domain | 0 | DIRECT |
L-aspartase-like | 0 | DIRECT |
ARID-like | 0 | DIRECT |
HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
Aquaporin-like | 0 | DIRECT |
Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
VPS9 domain | 0 | DIRECT |
Periplasmic binding protein-like II | 0 | DIRECT |
LEM domain | 0 | DIRECT |
Proton glutamate symport protein | 0 | DIRECT |
Class II aaRS ABD-related | 0 | DIRECT |
Complement control module/SCR domain | 0 | DIRECT |
Fibrinogen C-terminal domain-like | 0 | DIRECT |
Cation efflux protein cytoplasmic domain-like | 0 | DIRECT |
Carbon-nitrogen hydrolase | 0 | DIRECT |
FAD-binding/transporter-associated domain-like | 0 | DIRECT |
lambda repressor-like DNA-binding domains | 0 | DIRECT |
Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0 | DIRECT |
Thiamin diphosphate-binding fold (THDP-binding) | 0 | DIRECT |
Small-conductance potassium channel | 0 | DIRECT |
Creatinase/prolidase N-terminal domain | 0 | DIRECT |
GroEL-intermediate domain like | 0 | DIRECT |
Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | DIRECT |
HRDC-like | 0 | DIRECT |
GAS2 domain-like | 0 | DIRECT |
Acid phosphatase/Vanadium-dependent haloperoxidase | 0 | DIRECT |
BEACH domain | 0 | DIRECT |
Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | DIRECT |
PEBP-like | 0 | DIRECT |
PAP/OAS1 substrate-binding domain | 0 | DIRECT |
Outer arm dynein light chain 1 | 0 | DIRECT |
2Fe-2S ferredoxin-like | 0 | DIRECT |
ISP domain | 0 | DIRECT |
Bacterial exopeptidase dimerisation domain | 0 | DIRECT |
PLC-like phosphodiesterases | 0 | DIRECT |
beta-lactamase/transpeptidase-like | 0 | DIRECT |
Aminoacid dehydrogenase-like, N-terminal domain | 0 | DIRECT |
Elafin-like | 0 | DIRECT |
Chaperone J-domain | 0 | DIRECT |
Putative DNA-binding domain | 0 | DIRECT |
Formate/glycerate dehydrogenase catalytic domain-like | 0 | DIRECT |
WGR domain-like | 0 | DIRECT |
alpha/beta knot | 0 | DIRECT |
Tubulin nucleotide-binding domain-like | 0 | DIRECT |
Arginase/deacetylase | 0 | DIRECT |
Pentein | 0 | DIRECT |
Nucleotidyltransferase | 0 | DIRECT |
Retrovirus zinc finger-like domains | 0 | DIRECT |
Integrin domains | 0 | DIRECT |
FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | DIRECT |
SIS domain | 0 | DIRECT |
CO dehydrogenase ISP C-domain like | 0 | DIRECT |
Carbonic anhydrase | 0 | DIRECT |
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | DIRECT |
Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
TGS-like | 0 | DIRECT |
Sec1/munc18-like (SM) proteins | 0 | DIRECT |
Annexin | 0 | DIRECT |
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
Terpenoid synthases | 0 | DIRECT |
14-3-3 protein | 0 | DIRECT |
Carbohydrate phosphatase | 0 | DIRECT |
Lipovitellin-phosvitin complex, superhelical domain | 0 | DIRECT |
Tim10-like | 0 | DIRECT |
PLP-binding barrel | 0 | DIRECT |
Carboxypeptidase regulatory domain-like | 0 | DIRECT |
Translational machinery components | 0 | DIRECT |
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
Sec63 N-terminal domain-like | 0 | DIRECT |
Subtilisin-like | 0 | DIRECT |
Glycolipid transfer protein, GLTP | 0 | DIRECT |
Succinyl-CoA synthetase domains | 0 | DIRECT |
Cytochrome c | 0 | DIRECT |
Heme-dependent catalase-like | 0 | DIRECT |
FAD-linked oxidases, C-terminal domain | 0 | DIRECT |
P-loop containing nucleoside triphosphate hydrolases | 0.00000006269 | DIRECT |
PH domain-like | 0.00001559 | DIRECT |
PDZ domain-like | 0.007473 | INHERITED FROM: protein expression variant || drug resistant || acetylcholinesterase inhibitor response variant || aldicarb response variant |
TPR-like | 0.01055 | INHERITED FROM: ivermectin resistant || associative learning variant || positive chemotaxis defective || light body touch resistant || ivermectin response variant || antihelmintic response variant |
Periplasmic binding protein-like I | 0.01206 | INHERITED FROM: benzaldehyde chemotaxis variant || lithium chemotaxis defective || iodide chemotaxis defective || chemotaxis variant || associative learning variant || aqueous chemosensory response variant || organism environmental stimulus response variant || magnesium chemotaxis defective || diacetyl chemotaxis variant || alkaline pH chemotaxis variant || organism temperature response variant || AWC odorant chemotaxis defective || carbon dioxide avoidance variant || chemosensory response variant || AWC odorant chemotaxis variant || memory retention defective || bromide chemotaxis defective || second messenger mediated signaling variant || thermotaxis variant || iodide chemotaxis variant || thermosensory behavior variant || chemosensory behavior variant || aqueous positive chemotaxis variant || bromide chemotaxis variant || mechanosensation variant |
ARM repeat | 0.01567 | INHERITED FROM: gene expression variant || protein expression variant || sexually dimorphic physiology variant || RNAi response variant || sick || organism metabolism processing variant |
ABC transporter transmembrane region | 0.01707 | INHERITED FROM: colchicine hypersensitive || organism environmental stimulus response variant || metal response variant || cadmium response variant || RNAi response variant || RNAi resistant |
PapD-like | 0.0201 | INHERITED FROM: larval growth variant || dauer lifespan variant || slow growth || dauer lifespan extended || developmental growth variant || dauer metabolism variant || lipid metabolism variant || fat content variant || larval arrest |
Protein kinase-like (PK-like) | 0.04005 | INHERITED FROM: mid larval arrest || colchicine resistant || kinase activity reduced || protein phosphorylation reduced || chemotaxis variant || organism osmostic stress hypersensitive || protein phosphorylation variant || organism environmental stimulus response variant || metal response variant || protein expression variant || dauer development variant || alkaline pH chemotaxis variant || chemical response variant || metabolic pathway variant || life span variant || pathogen induced gene expression variant || lipid synthesis increased || chemosensory response variant || second messenger mediated signaling variant || egg laying response to food variant || chemosensory behavior variant || aldicarb response variant || mechanosensation variant || protein subcellular localization variant || positive chemotaxis variant || anoxia resistant || octanol chemotaxis defective || protein modification variant || conflicting sensory integration variant || drug induced gene expression variant |
Nucleic acid-binding proteins | 0.04102 | INHERITED FROM: hydroxyurea hypersensitive || hermaphrodite physiology variant || hypoxia resistant || hydroxyurea response variant || sexually dimorphic physiology variant || sick || nonsense mRNA accumulation || mRNA surveillance defective |
Homeodomain-like | 0.04592 | INHERITED FROM: growth rate variant || level of transgene expression variant || inhibitor of serotonin uptake variant || imipramine resistant || carbon dioxide avoidance variant || ectopic expression transgene || egg laying imipramine resistant || adrenergic receptor antagonist response variant || organism metabolism processing variant || protein degradation variant || carbon dioxide response variant |
WD40 repeat-like | 0.05454 | INHERITED FROM: hermaphrodite physiology variant || protein aggregation induced behavior variant || antimicrobial gene expression variant || sexually dimorphic physiology variant || protein aggregation variant || late larval arrest || protein protein interaction variant || aldicarb response variant || osmotic avoidance variant || organism metabolism processing variant || early larval arrest |
CCCH zinc finger | 0.06072 | INHERITED FROM: mRNA expression ectopic || gene expression variant || transgene expression variant || ectopic expression transgene |
FYVE/PHD zinc finger | 0.06888 | INHERITED FROM: protein methylation variant || organism UV response variant || gene expression variant || organism UV hypersensitive || ectopic expression transgene || organism metabolism processing variant || protein modification variant |
Translation proteins | 0.07633 | INHERITED FROM: hermaphrodite physiology variant || gene expression variant || protein phosphorylation variant || oocyte physiology variant || mRNA levels increased || sexually dimorphic physiology variant || transgene expression variant || receptor mediated endocytosis defective || sick || protein aggregation variant || proteasome core activity variant || protein protein interaction variant || protein phosphorylation increased || organism metabolism processing variant |
"Winged helix" DNA-binding domain | 0.08457 | INHERITED FROM: paraquat hypersensitive || gene expression variant || protein expression increased || protein aggregation induced behavior variant || shortened life span || anesthetic response variant || germline transgene silencing variant || life span variant || spontaneous mutation rate increased || protein aggregation variant || protein protein interaction variant || chemical hypersensitive || organism metabolism processing variant |
Ankyrin repeat | 0.08941 | INHERITED FROM: organism heat response variant || chemotaxis variant || octanol chemotaxis variant || odorant negative chemotaxis defective || mechanosensation variant || octanol chemotaxis defective |
HLH, helix-loop-helix DNA-binding domain | 0.0896 | INHERITED FROM: pathogen resistance increased || RNA expression variant || aqueous positive chemotaxis defective || lysine chemotaxis defective || fungal resistance increased || gene expression level reduced || hypoxia response variant || ectopic expression transgene || organism metabolism processing variant |
Nucleotide cyclase | 0.0896 | INHERITED FROM: lithium chemotaxis defective || iodide chemotaxis defective || chemotaxis variant || aqueous chemosensory response variant || organism environmental stimulus response variant || magnesium chemotaxis defective || cation positive chemotaxis variant || diacetyl chemotaxis variant || alkaline pH chemotaxis variant || cation positive chemotaxis defective || AWC odorant chemotaxis defective || anion positive chemotaxis defective || anion positive chemotaxis variant || chemosensory response variant || AWC odorant chemotaxis variant || bromide chemotaxis defective || second messenger mediated signaling variant || iodide chemotaxis variant || chemosensory behavior variant || bromide chemotaxis variant || osmotic avoidance variant || positive chemotaxis variant || carbon dioxide response variant |
SMAD/FHA domain | 0.09584 | INHERITED FROM: fat content reduced || aldicarb response variant |
BRCT domain | 0.09584 | INHERITED FROM: organism ionizing radiation response variant |
Calcium ATPase, transmembrane domain M | 0.1072 | INHERITED FROM: nicotine hypersensitive || lipid composition variant |
SH3-domain | 0.1117 | INHERITED FROM: protein metabolism variant || protein phosphorylation variant || protein expression variant || protein expression reduced || aldicarb response variant |
Regulator of G-protein signaling, RGS | 0.1201 | INHERITED FROM: chemotaxis variant || negative chemotaxis variant || chemosensory response variant || chemosensory behavior variant || mechanosensation variant |
Metal cation-transporting ATPase, ATP-binding domain N | 0.1201 | INHERITED FROM: organism environmental stimulus response variant || nicotine hypersensitive || lipid composition variant |
EGF/Laminin | 0.123 | INHERITED FROM: octanol chemotaxis variant || odorant negative chemotaxis defective || octanol chemotaxis defective |
Calcium ATPase, transduction domain A | 0.1342 | INHERITED FROM: organism environmental stimulus response variant || nicotine hypersensitive |
Acid proteases | 0.1342 | INHERITED FROM: gene expression variant || hypoosmotic shock hypersensitive || osmotic integrity variant || protein interaction variant || transgene expression variant || protein aggregation variant || transgene subcellular localization variant || protein protein interaction variant || organism metabolism processing variant |
Cysteine-rich domain | 0.1415 | INHERITED FROM: odorant positive chemotaxis variant || antimicrobial gene expression variant || organism temperature response variant || odorant chemosensory response variant || acetylcholinesterase inhibitor response variant || response to injury variant || thermotaxis variant || thermosensory behavior variant || aldicarb response variant || organism pathogen response variant || protein subcellular localization variant || positive chemotaxis variant || organism metabolism processing variant || bacterially unswollen || drug induced gene expression variant |
Quinoprotein alcohol dehydrogenase-like | 0.1501 | INHERITED FROM: mid larval arrest || drug response variant || mRNA levels increased || L2 arrest || hypoxia response variant || protein degradation variant |
Multidrug efflux transporter AcrB transmembrane domain | 0.1549 | INHERITED FROM: egg integrity defective early emb || positive chemotaxis defective || odorant chemosensory response variant || embryo osmotic integrity defective early emb || odorant positive chemotaxis defective |
Cytochrome P450 | 0.167 | INHERITED FROM: metal response variant || cadmium response variant || metabolite content decreased |
DBL homology domain (DH-domain) | 0.1678 | INHERITED FROM: pathogen resistance increased || organism environmental stimulus response variant || aldicarb response variant || organism pathogen response variant || bacterially unswollen |
HMG-box | 0.1678 | INHERITED FROM: transgene expression variant || maintenance of gene silencing variant |
ClpP/crotonase | 0.1678 | INHERITED FROM: level of transgene expression variant || lipid metabolism variant || fat content variant |
E set domains | 0.171 | INHERITED FROM: paraquat hypersensitive |
(Trans)glycosidases | 0.1772 | INHERITED FROM: pathogen susceptibility increased |
Cyclin-like | 0.2192 | INHERITED FROM: protein phosphorylation reduced || level of transgene expression variant || protein phosphorylation variant |
Cysteine proteinases | 0.2254 | INHERITED FROM: paraquat hypersensitive || hypoosmotic shock hypersensitive || osmotic integrity variant || protein interaction variant || protein aggregation variant || protein protein interaction variant || pattern of transgene expression variant || organism metabolism processing variant |
Bromodomain | 0.2334 | INHERITED FROM: organism UV response variant || gene expression variant || drug adaptation variant || anesthetic resistant || anesthetic response variant || organism UV hypersensitive || ethanol resistant || sick || acute functional tolerance to alcohol defective || organism metabolism processing variant |
6-phosphogluconate dehydrogenase C-terminal domain-like | 0.2334 | INHERITED FROM: lipid metabolism variant || fat content variant |
Tudor/PWWP/MBT | 0.2334 | INHERITED FROM: pattern of transgene expression variant |
POZ domain | 0.2422 | INHERITED FROM: protein aggregation induced behavior variant || L1 arrest || resistant to protein aggregation induced paralysis || chemical hypersensitive || early larval arrest |
RNA-binding domain, RBD | 0.2527 | INHERITED FROM: alternative splicing variant || RNA metabolism variant || RNA processing variant || RNA expression variant || mRNA export variant || antimicrobial gene expression variant || maintenance of gene silencing variant || sick || starvation induced apoptosis variant || innate immune response variant || no induction of antimicrobial peptide expression after infection || organism metabolism processing variant |
Lipocalins | 0.2595 | INHERITED FROM: paraquat hypersensitive || fat content increased || lipid metabolism variant || fat content variant |
SNARE-like | 0.2605 | INHERITED FROM: aldicarb resistant || gene expression variant || transgene expression variant || sick || transgene subcellular localization variant || acetylcholinesterase inhibitor resistant || pattern of transgene expression variant || organism metabolism processing variant |
Metallo-dependent phosphatases | 0.2619 | INHERITED FROM: germ cell resistant ionizing radiation || radiation induced germ cell apoptosis resistant |
Translation proteins SH3-like domain | 0.3231 | INHERITED FROM: gene expression variant || transgene expression variant || protein aggregation variant || protein protein interaction variant || organism metabolism processing variant || early larval arrest |
Cation efflux protein transmembrane domain-like | 0.3231 | INHERITED FROM: metal response variant || cadmium hypersensitive || manganese response variant || manganese toxicity resistant |
PX domain | 0.3231 | INHERITED FROM: protein expression variant || protein expression reduced || protein subcellular localization variant |
HAD-like | 0.3421 | INHERITED FROM: nicotine hypersensitive |
Nicotinic receptor ligand binding domain-like | 0.3545 | INHERITED FROM: benzaldehyde chemotaxis variant || drug response variant || chemotaxis variant || hypoosmotic shock hypersensitive || organism environmental stimulus response variant || DMPP response variant || chemical response variant || organism temperature response variant || selenium response variant || nicotine resistant || cholinergic agonist resistant || chemosensory response variant || AWC odorant chemotaxis variant || antihelmintic response variant || sodium chloride chemotaxis variant || thermosensory behavior variant || chemosensory behavior variant || mechanosensation variant || slowing response on food variant || positive chemotaxis variant |
Ubiquitin-like | 0.3716 | INHERITED FROM: protein interaction variant || heteroplasmy || protein aggregation variant || protein protein interaction variant || organism metabolism processing variant |
Neurotransmitter-gated ion-channel transmembrane pore | 0.3906 | INHERITED FROM: benzaldehyde chemotaxis variant || drug response variant || chemotaxis variant || hypoosmotic shock hypersensitive || organism environmental stimulus response variant || DMPP response variant || chemical response variant || organism temperature response variant || selenium response variant || nicotine resistant || cholinergic agonist resistant || chemosensory response variant || AWC odorant chemotaxis variant || antihelmintic response variant || sodium chloride chemotaxis variant || thermosensory behavior variant || chemosensory behavior variant || mechanosensation variant || slowing response on food variant || positive chemotaxis variant |
RNI-like | 0.3971 | INHERITED FROM: resistant to protein aggregation induced paralysis |
HD-domain/PDEase-like | 0.3984 | INHERITED FROM: organism temperature response variant || thermotaxis variant || thermosensory behavior variant |
FKBP-like | 0.3984 | INHERITED FROM: protein interaction variant || protein aggregation variant || transgene subcellular localization variant || protein protein interaction variant || pattern of transgene expression variant |
Class II aaRS and biotin synthetases | 0.4143 | INHERITED FROM: hermaphrodite physiology variant || gene expression variant || oxygen response variant || hypoxia resistant || organism environmental stimulus response variant || oocyte physiology variant || sexually dimorphic physiology variant || transgene expression variant || receptor mediated endocytosis defective || hypoxia response variant || organism metabolism processing variant |
DHS-like NAD/FAD-binding domain | 0.4431 | INHERITED FROM: protein acetylation variant || metabolic pathway variant |
Myosin rod fragments | 0.4431 | INHERITED FROM: hermaphrodite physiology variant || drug resistant || sexually dimorphic physiology variant |
PRTase-like | 0.4431 | INHERITED FROM: drug resistant || Fluorouracil resistant |
Hect, E3 ligase catalytic domain | 0.4431 | INHERITED FROM: gene expression variant || protein aggregation induced behavior variant || germ cell ionizing radiation response variant || protein interaction variant || transgene expression variant || protein aggregation variant || transgene subcellular localization variant || protein protein interaction variant || cell stress response variant || pattern of transgene expression variant || organism metabolism processing variant |
Ribosomal protein S5 domain 2-like | 0.4749 | INHERITED FROM: early larval arrest |
Galactose-binding domain-like | 0.4749 | INHERITED FROM: protein interaction variant || protein aggregation variant || protein protein interaction variant |
WW domain | 0.4789 | INHERITED FROM: aldicarb resistant || maintenance of gene silencing variant |
Sm-like ribonucleoproteins | 0.4789 | INHERITED FROM: hermaphrodite physiology variant || organism heat response variant || gene expression variant || unfolded protein response variant || sexually dimorphic physiology variant || transgene expression variant || life span variant || receptor mediated endocytosis defective || sick || pattern of transgene expression variant || protein subcellular localization variant |
Cystine-knot cytokines | 0.4789 | INHERITED FROM: nicotine response variant || levamisole response variant |
SH2 domain | 0.4824 | INHERITED FROM: protein expression variant || level of protein expression variant || protein expression reduced |
Ferredoxin reductase-like, C-terminal NADP-linked domain | 0.4892 | INHERITED FROM: pattern protein expression variant |
Zinc beta-ribbon | 0.4892 | INHERITED FROM: receptor mediated endocytosis defective |
Calpain large subunit, middle domain (domain III) | 0.4892 | INHERITED FROM: protein metabolism variant || metabolic pathway variant || protein degradation variant |
Riboflavin synthase domain-like | 0.4892 | INHERITED FROM: pattern protein expression variant |
FAD/NAD(P)-binding domain | 0.5006 | INHERITED FROM: pesticide response variant || ATP levels reduced || life span variant || ATP levels variant |
FAD-linked reductases, C-terminal domain | 0.5139 | INHERITED FROM: life span variant |
Voltage-gated potassium channels | 0.5149 | INHERITED FROM: growth rate variant || positive chemotaxis defective || serotonin response variant || serotonin resistant || mechanosensation variant || adrenergic receptor antagonist response variant || protein degradation variant |
Nucleotidylyl transferase | 0.5216 | INHERITED FROM: oxygen response variant || hypoxia resistant || organism environmental stimulus response variant || antimicrobial gene expression variant || transgene expression increased || paraquat resistant || hypoxia response variant || innate immune response variant || organism metabolism processing variant |
SAM/Pointed domain | 0.5216 | INHERITED FROM: gene expression level reduced || aldicarb response variant |
SET domain | 0.5239 | INHERITED FROM: protein methylation variant || gene expression variant || protein metabolism variant || shortened life span || maintenance of gene silencing variant || life span variant || ectopic expression antibody || RNAi response variant || spontaneous mutation rate increased || histone methylation variant || dosage compensation variant || pattern of transgene expression variant || organism metabolism processing variant || protein modification variant |
UBC-like | 0.5239 | INHERITED FROM: protein interaction variant || sick || protein aggregation variant || transgene subcellular localization variant || late larval arrest || protein protein interaction variant || pattern of transgene expression variant || organism metabolism processing variant |
Seven-hairpin glycosidases | 0.5446 | INHERITED FROM: protein aggregation variant || protein protein interaction variant || extended life span |
Multidrug resistance efflux transporter EmrE | 0.55 | INHERITED FROM: pathogen resistance increased || bacterially unswollen |
PLP-dependent transferases | 0.5676 | INHERITED FROM: germ cell resistant ionizing radiation || radiation induced germ cell apoptosis resistant |
C2 domain (Calcium/lipid-binding domain, CaLB) | 0.5836 | INHERITED FROM: growth rate variant || organism environmental stimulus response variant || somatic sheath physiology variant || protein expression variant || antimicrobial gene expression variant || drug resistant || chemical response variant || gonad sheath contractions variant || RNAi response variant || response to injury variant || gonad sheath contraction rate reduced || aging variant || egg laying serotonin variant || cell stress response variant || protein subcellular localization variant || drug induced gene expression variant |
KA1-like | 0.5996 | INHERITED FROM: RNA expression variant |
Nucleotide-binding domain | 0.5996 | INHERITED FROM: extended life span |
Di-copper centre-containing domain | 0.5996 | INHERITED FROM: organism stress response variant || cell ionizing radiation response variant || germ cell ionizing radiation response variant || organism ionizing radiation response variant || cell stress response variant |
HIT/MYND zinc finger-like | 0.6261 | INHERITED FROM: pattern of transgene expression variant |
S-adenosyl-L-methionine-dependent methyltransferases | 0.6272 | INHERITED FROM: gamma ray induced apoptosis increased || cell gamma ray response variant || organism gamma ray response variant |
MFS general substrate transporter | 0.6647 | INHERITED FROM: organism high sodium chloride hypersensitive |
Frizzled cysteine-rich domain | 0.6648 | INHERITED FROM: transgene expression reduced || antibody staining variant |
4Fe-4S ferredoxins | 0.6648 | INHERITED FROM: transgene expression increased || life span variant |
S15/NS1 RNA-binding domain | 0.6648 | INHERITED FROM: transgene expression increased |
GST C-terminal domain-like | 0.6707 | INHERITED FROM: organism stress response variant || organism environmental stimulus response variant || metal response variant || organism heat hypersensitive || enzyme activity reduced || organism electrophilic stress hypersensitive || enzyme activity variant || cadmium hypersensitive |
alpha/beta-Hydrolases | 0.729 | INHERITED FROM: acetylcholinesterase reduced || acetylcholinesterase activity variant |
EF-hand | 0.735 | INHERITED FROM: somatic sheath physiology variant || protein interaction variant || gonad sheath contractions variant || osmotic stress response variant || protein aggregation variant || aldicarb response variant |
Fibronectin type III | 0.7353 | INHERITED FROM: growth rate variant || protein metabolism variant |
ADC-like | 0.7358 | INHERITED FROM: protein metabolism variant || transgene expression reduced || protein interaction variant || metabolic pathway variant || protein aggregation variant || protein protein interaction variant |
MIT domain | 0.7358 | INHERITED FROM: protein interaction variant || protein aggregation variant || protein protein interaction variant |
Clavaminate synthase-like | 0.7895 | INHERITED FROM: protein methylation variant || life span variant || histone methylation variant |
NAD kinase/diacylglycerol kinase-like | 0.7948 | INHERITED FROM: organism stress response variant || thermotaxis variant || thermosensory behavior variant |
CoA-dependent acyltransferases | 0.8028 | INHERITED FROM: organism metabolism processing variant |
Cyclophilin-like | 0.8028 | INHERITED FROM: gene expression variant || protein interaction variant || transgene expression variant || protein aggregation variant || transgene subcellular localization variant || protein protein interaction variant || pattern of transgene expression variant |
UBA-like | 0.8141 | INHERITED FROM: protein aggregation variant || protein protein interaction variant |
SNF-like | 0.8347 | INHERITED FROM: drug hypersensitive |
Leucine zipper domain | 0.8406 | INHERITED FROM: mRNA levels reduced || level of transgene expression variant || transgene expression reduced || mRNA expression variant || pathogen susceptibility increased || pore forming toxin response variant |
GTPase activation domain, GAP | 0.8492 | INHERITED FROM: protein expression variant |
Eukaryotic type KH-domain (KH-domain type I) | 0.8492 | INHERITED FROM: RNA expression variant |
Thioredoxin-like | 0.8798 | INHERITED FROM: organism stress response variant || metal response variant || organism heat hypersensitive || paraquat response variant || enzyme activity reduced || organism electrophilic stress hypersensitive || enzyme activity variant || cadmium hypersensitive |
Glucocorticoid receptor-like (DNA-binding domain) | 0.8892 | INHERITED FROM: level of transgene expression variant || fat content increased || transgene expression reduced || gene expression level reduced || SDS sensitive dauer || gene expression level high || dauer resistance to harsh conditions variant |
p53-like transcription factors | 0.8894 | INHERITED FROM: level of transgene expression variant || gene expression level reduced || ectopic expression transgene |
Immunoglobulin | 0.8945 | INHERITED FROM: growth rate variant || aldicarb response variant || protein degradation variant |
Ribonuclease PH domain 2-like | 0.9179 | INHERITED FROM: early larval arrest |
DNA/RNA polymerases | 0.9215 | INHERITED FROM: DNA metabolism variant || DNA repair variant |
Saposin | 0.9441 | INHERITED FROM: level of transgene expression variant || transgene expression reduced || germ cell ionizing radiation response variant || germ cell resistant ionizing radiation || radiation induced germ cell apoptosis resistant || pathogen load variant || increased pathogen survival |
Ribonuclease H-like | 0.961 | INHERITED FROM: RNA expression variant || siRNA expression variant || RNAi enhanced || maintenance of gene silencing variant || RNAi response variant || 21U RNA expression variant || somatic transgene silencing variant |
PAZ domain | 0.9799 | INHERITED FROM: RNA expression variant || siRNA expression variant || RNAi enhanced || mRNA levels increased || maintenance of gene silencing variant || RNAi response variant || 21U RNA expression variant || somatic transgene silencing variant |
Ligand-binding domain in the NO signalling and Golgi transport | 0.9906 | INHERITED FROM: carbon dioxide avoidance variant || carbon dioxide response variant |
Bet v1-like | 1 | INHERITED FROM: growth rate variant |
B-box zinc-binding domain | 1 | INHERITED FROM: gene expression variant || protein interaction variant || transgene expression variant || protein aggregation variant || transgene subcellular localization variant || protein protein interaction variant || organism metabolism processing variant |
Snake toxin-like | 1 | INHERITED FROM: fat content reduced |
RING/U-box | 1 | INHERITED FROM: cell ionizing radiation response variant || gene expression variant || germ cell hypersensitive ionizing radiation || germ cell ionizing radiation response variant || organism ionizing radiation response variant || protein interaction variant || protein aggregation variant || transgene subcellular localization variant || protein protein interaction variant || pattern of transgene expression variant || organism metabolism processing variant |
Family A G protein-coupled receptor-like | 1 | INHERITED FROM: serotonin induced pumping variant || serotonin induced fat reduction variant || male tail curling serotonin variant || locomotion rate serotonin variant |
Nuclear receptor ligand-binding domain | 1 | INHERITED FROM: level of transgene expression variant || fat content increased || transgene expression reduced || gene expression level reduced || SDS sensitive dauer || gene expression level high || lipid metabolism variant || dauer resistance to harsh conditions variant |
F-box domain | 1 | INHERITED FROM: resistant to protein aggregation induced paralysis |
beta-beta-alpha zinc fingers | 1 | INHERITED FROM: inhibitor of serotonin uptake variant || imipramine resistant || egg laying imipramine resistant || egg laying serotonin resistant || organism metabolism processing variant |
Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
Radical SAM enzymes | 0 | Direct |
Nop domain | 0 | Direct |
Cadherin-like | 0 | Direct |
Cullin repeat-like | 0 | Direct |
5' to 3' exonuclease, C-terminal subdomain | 0 | Direct |
Acyl-CoA dehydrogenase NM domain-like | 0 | Direct |
SMAD MH1 domain | 0 | Direct |
Lamin A/C globular tail domain | 0 | Direct |
AN1-like Zinc finger | 0 | Direct |
Spectrin repeat | 0 | Direct |
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | Direct |
Hormone receptor domain | 0 | Direct |
ACP-like | 0 | Direct |
PEP carboxykinase N-terminal domain | 0 | Direct |
FF domain | 0 | Direct |
HCP-like | 0 | Direct |
Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | Direct |
C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
WWE domain | 0 | Direct |
Phosphoglucomutase, C-terminal domain | 0 | Direct |
alpha-catenin/vinculin-like | 0 | Direct |
Nucleoside diphosphate kinase, NDK | 0 | Direct |
Helical domain of Sec23/24 | 0 | Direct |
Zn-binding ribosomal proteins | 0 | Direct |
Tricorn protease domain 2 | 0 | Direct |
DEATH domain | 0 | Direct |
Subdomain of clathrin and coatomer appendage domain | 0 | Direct |
Galactose mutarotase-like | 0 | Direct |
PUA domain-like | 0 | Direct |
Phosphoenolpyruvate/pyruvate domain | 0 | Direct |
Ribokinase-like | 0 | Direct |
Band 7/SPFH domain | 0 | Direct |
GroEL apical domain-like | 0 | Direct |
Surp module (SWAP domain) | 0 | Direct |
Cdc48 domain 2-like | 0 | Direct |
Ribulose-phoshate binding barrel | 0 | Direct |
ArfGap/RecO-like zinc finger | 0 | Direct |
MIR domain | 0 | Direct |
CAD & PB1 domains | 0 | Direct |
Hedgehog/intein (Hint) domain | 0 | Direct |
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
Glutathione synthetase ATP-binding domain-like | 0 | Direct |
TK C-terminal domain-like | 0 | Direct |
FAD-dependent thiol oxidase | 0 | Direct |
ADP-ribosylation | 0 | Direct |
LDH C-terminal domain-like | 0 | Direct |
Insulin-like | 0 | Direct |
Single hybrid motif | 0 | Direct |
Galactose oxidase, central domain | 0 | Direct |
Ribosomal protein L1 | 0 | Direct |
PGBD-like | 0 | Direct |
Second domain of FERM | 0 | Direct |
MgtE membrane domain-like | 0 | Direct |
Ribosomal protein S10 | 0 | Direct |
Phosphoglucomutase, first 3 domains | 0 | Direct |
Ferritin-like | 0 | Direct |
Tubby C-terminal domain-like | 0 | Direct |
Restriction endonuclease-like | 0 | Direct |
SWIB/MDM2 domain | 0 | Direct |
Chromo domain-like | 0 | Direct |
Cu,Zn superoxide dismutase-like | 0 | Direct |
Chitinase insertion domain | 0 | Direct |
Zn-finger domain of Sec23/24 | 0 | Direct |
Oxysterol-binding protein-like | 0 | Direct |
PYP-like sensor domain (PAS domain) | 0 | Direct |
t-snare proteins | 0 | Direct |
N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
DNA ligase/mRNA capping enzyme, catalytic domain | 0 | Direct |
MOSC N-terminal domain-like | 0 | Direct |
PHM/PNGase F | 0 | Direct |
PABC (PABP) domain | 0 | Direct |
Clc chloride channel | 0 | Direct |
Phoshotransferase/anion transport protein | 0 | Direct |
SAND domain-like | 0 | Direct |
GroES-like | 0 | Direct |
Families 57/38 glycoside transferase middle domain | 0 | Direct |
Ran binding protein zinc finger-like | 0 | Direct |
JAB1/MPN domain | 0 | Direct |
Clathrin adaptor appendage domain | 0 | Direct |
ENTH/VHS domain | 0 | Direct |
FtsH protease domain-like | 0 | Direct |
ALDH-like | 0 | Direct |
Histone-fold | 0 | Direct |
PurM N-terminal domain-like | 0 | Direct |
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | Direct |
HSP90 C-terminal domain | 0 | Direct |
DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
LysM domain | 0 | Direct |
Acetyl-CoA synthetase-like | 0 | Direct |
PreATP-grasp domain | 0 | Direct |
Cullin homology domain | 0 | Direct |
HSP20-like chaperones | 0 | Direct |
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
Thyroglobulin type-1 domain | 0 | Direct |
Domain of poly(ADP-ribose) polymerase | 0 | Direct |
Integrin alpha N-terminal domain | 0 | Direct |
ThrRS/AlaRS common domain | 0 | Direct |
DNA repair protein MutS, domain III | 0 | Direct |
beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | Direct |
Polo-box domain | 0 | Direct |
Class I glutamine amidotransferase-like | 0 | Direct |
MFPT repeat-like | 0 | Direct |
Tubulin C-terminal domain-like | 0 | Direct |
Troponin coil-coiled subunits | 0 | Direct |
Sec7 domain | 0 | Direct |
NagB/RpiA/CoA transferase-like | 0 | Direct |
Pepsin inhibitor-3 | 0 | Direct |
cAMP-binding domain-like | 0 | Direct |
PK beta-barrel domain-like | 0 | Direct |
ValRS/IleRS/LeuRS editing domain | 0 | Direct |
Cystatin/monellin | 0 | Direct |
Molybdenum cofactor-binding domain | 0 | Direct |
GAT-like domain | 0 | Direct |
F1F0 ATP synthase subunit C | 0 | Direct |
R3H domain | 0 | Direct |
eIF4e-like | 0 | Direct |
Thiolase-like | 0 | Direct |
Ribosomal L27 protein-like | 0 | Direct |
S-adenosylmethionine synthetase | 0 | Direct |
Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | Direct |
Ribosomal protein L10-like | 0 | Direct |
C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
Ribosomal proteins S24e, L23 and L15e | 0 | Direct |
Smc hinge domain | 0 | Direct |
Kringle-like | 0 | Direct |
L30e-like | 0 | Direct |
Skp1 dimerisation domain-like | 0 | Direct |
3-carboxy-cis,cis-mucoante lactonizing enzyme | 0 | Direct |
Ribosomal protein S18 | 0 | Direct |
Doublecortin (DC) | 0 | Direct |
Profilin (actin-binding protein) | 0 | Direct |
Rap/Ran-GAP | 0 | Direct |
Heme-dependent peroxidases | 0 | Direct |
Invertebrate chitin-binding proteins | 0 | Direct |
Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
CBD9-like | 0 | Direct |
GYF domain | 0 | Direct |
Actin-like ATPase domain | 0 | Direct |
Transducin (heterotrimeric G protein), gamma chain | 0 | Direct |
Diaminopimelate epimerase-like | 0 | Direct |
Transducin (alpha subunit), insertion domain | 0 | Direct |
SAICAR synthase-like | 0 | Direct |
Nucleoporin domain | 0 | Direct |
Terpenoid cyclases/Protein prenyltransferases | 0 | Direct |
PEP carboxykinase-like | 0 | Direct |
Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
Hypothetical protein c14orf129, hspc210 | 0 | Direct |
N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0 | Direct |
Aldolase | 0 | Direct |
Isocitrate/Isopropylmalate dehydrogenase-like | 0 | Direct |
Mitochondrial carrier | 0 | Direct |
Rudiment single hybrid motif | 0 | Direct |
YWTD domain | 0 | Direct |
dsRNA-binding domain-like | 0 | Direct |
RBP11-like subunits of RNA polymerase | 0 | Direct |
Protease propeptides/inhibitors | 0 | Direct |
SCP-like | 0 | Direct |
YbiA-like | 0 | Direct |
Citrate synthase | 0 | Direct |
GroEL equatorial domain-like | 0 | Direct |
CO dehydrogenase molybdoprotein N-domain-like | 0 | Direct |
Intermediate filament protein, coiled coil region | 0 | Direct |
PIN domain-like | 0 | Direct |
PurM C-terminal domain-like | 0 | Direct |
SPOC domain-like | 0 | Direct |
Activating enzymes of the ubiquitin-like proteins | 0 | Direct |
Blood coagulation inhibitor (disintegrin) | 0 | Direct |
CRAL/TRIO N-terminal domain | 0 | Direct |
L-aspartase-like | 0 | Direct |
ARID-like | 0 | Direct |
HSP40/DnaJ peptide-binding domain | 0 | Direct |
Aquaporin-like | 0 | Direct |
Composite domain of metallo-dependent hydrolases | 0 | Direct |
VPS9 domain | 0 | Direct |
Periplasmic binding protein-like II | 0 | Direct |
LEM domain | 0 | Direct |
Proton glutamate symport protein | 0 | Direct |
Class II aaRS ABD-related | 0 | Direct |
Complement control module/SCR domain | 0 | Direct |
Fibrinogen C-terminal domain-like | 0 | Direct |
Cation efflux protein cytoplasmic domain-like | 0 | Direct |
Carbon-nitrogen hydrolase | 0 | Direct |
FAD-binding/transporter-associated domain-like | 0 | Direct |
lambda repressor-like DNA-binding domains | 0 | Direct |
Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0 | Direct |
Thiamin diphosphate-binding fold (THDP-binding) | 0 | Direct |
Small-conductance potassium channel | 0 | Direct |
Creatinase/prolidase N-terminal domain | 0 | Direct |
GroEL-intermediate domain like | 0 | Direct |
Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | Direct |
HRDC-like | 0 | Direct |
GAS2 domain-like | 0 | Direct |
Acid phosphatase/Vanadium-dependent haloperoxidase | 0 | Direct |
BEACH domain | 0 | Direct |
Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | Direct |
PEBP-like | 0 | Direct |
PAP/OAS1 substrate-binding domain | 0 | Direct |
Outer arm dynein light chain 1 | 0 | Direct |
2Fe-2S ferredoxin-like | 0 | Direct |
ISP domain | 0 | Direct |
Bacterial exopeptidase dimerisation domain | 0 | Direct |
PLC-like phosphodiesterases | 0 | Direct |
beta-lactamase/transpeptidase-like | 0 | Direct |
Aminoacid dehydrogenase-like, N-terminal domain | 0 | Direct |
Elafin-like | 0 | Direct |
Chaperone J-domain | 0 | Direct |
Putative DNA-binding domain | 0 | Direct |
Formate/glycerate dehydrogenase catalytic domain-like | 0 | Direct |
WGR domain-like | 0 | Direct |
alpha/beta knot | 0 | Direct |
Tubulin nucleotide-binding domain-like | 0 | Direct |
Arginase/deacetylase | 0 | Direct |
Pentein | 0 | Direct |
Nucleotidyltransferase | 0 | Direct |
Retrovirus zinc finger-like domains | 0 | Direct |
Integrin domains | 0 | Direct |
FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | Direct |
SIS domain | 0 | Direct |
CO dehydrogenase ISP C-domain like | 0 | Direct |
Carbonic anhydrase | 0 | Direct |
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | Direct |
Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
TGS-like | 0 | Direct |
Sec1/munc18-like (SM) proteins | 0 | Direct |
Annexin | 0 | Direct |
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
Terpenoid synthases | 0 | Direct |
14-3-3 protein | 0 | Direct |
Carbohydrate phosphatase | 0 | Direct |
Lipovitellin-phosvitin complex, superhelical domain | 0 | Direct |
Tim10-like | 0 | Direct |
PLP-binding barrel | 0 | Direct |
Carboxypeptidase regulatory domain-like | 0 | Direct |
Translational machinery components | 0 | Direct |
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | Direct |
Sec63 N-terminal domain-like | 0 | Direct |
Subtilisin-like | 0 | Direct |
Glycolipid transfer protein, GLTP | 0 | Direct |
Succinyl-CoA synthetase domains | 0 | Direct |
Cytochrome c | 0 | Direct |
Heme-dependent catalase-like | 0 | Direct |
FAD-linked oxidases, C-terminal domain | 0 | Direct |
P-loop containing nucleoside triphosphate hydrolases | 0.00000006269 | Direct |
PH domain-like | 0.00001559 | Direct |
PDZ domain-like | 0.007473 | Inherited |
TPR-like | 0.01055 | Inherited |
Periplasmic binding protein-like I | 0.01206 | Inherited |
ARM repeat | 0.01567 | Inherited |
ABC transporter transmembrane region | 0.01707 | Inherited |
PapD-like | 0.0201 | Inherited |
Protein kinase-like (PK-like) | 0.04005 | Inherited |
Nucleic acid-binding proteins | 0.04102 | Inherited |
Homeodomain-like | 0.04592 | Inherited |
WD40 repeat-like | 0.05454 | Inherited |
CCCH zinc finger | 0.06072 | Inherited |
FYVE/PHD zinc finger | 0.06888 | Inherited |
Translation proteins | 0.07633 | Inherited |
"Winged helix" DNA-binding domain | 0.08457 | Inherited |
Ankyrin repeat | 0.08941 | Inherited |
HLH, helix-loop-helix DNA-binding domain | 0.0896 | Inherited |
Nucleotide cyclase | 0.0896 | Inherited |
SMAD/FHA domain | 0.09584 | Inherited |
BRCT domain | 0.09584 | Inherited |
Calcium ATPase, transmembrane domain M | 0.1072 | Inherited |
SH3-domain | 0.1117 | Inherited |
Regulator of G-protein signaling, RGS | 0.1201 | Inherited |
Metal cation-transporting ATPase, ATP-binding domain N | 0.1201 | Inherited |
EGF/Laminin | 0.123 | Inherited |
Calcium ATPase, transduction domain A | 0.1342 | Inherited |
Acid proteases | 0.1342 | Inherited |
Cysteine-rich domain | 0.1415 | Inherited |
Quinoprotein alcohol dehydrogenase-like | 0.1501 | Inherited |
Multidrug efflux transporter AcrB transmembrane domain | 0.1549 | Inherited |
Cytochrome P450 | 0.167 | Inherited |
DBL homology domain (DH-domain) | 0.1678 | Inherited |
HMG-box | 0.1678 | Inherited |
ClpP/crotonase | 0.1678 | Inherited |
E set domains | 0.171 | Inherited |
(Trans)glycosidases | 0.1772 | Inherited |
Cyclin-like | 0.2192 | Inherited |
Cysteine proteinases | 0.2254 | Inherited |
Bromodomain | 0.2334 | Inherited |
6-phosphogluconate dehydrogenase C-terminal domain-like | 0.2334 | Inherited |
Tudor/PWWP/MBT | 0.2334 | Inherited |
POZ domain | 0.2422 | Inherited |
RNA-binding domain, RBD | 0.2527 | Inherited |
Lipocalins | 0.2595 | Inherited |
SNARE-like | 0.2605 | Inherited |
Metallo-dependent phosphatases | 0.2619 | Inherited |
Translation proteins SH3-like domain | 0.3231 | Inherited |
Cation efflux protein transmembrane domain-like | 0.3231 | Inherited |
PX domain | 0.3231 | Inherited |
HAD-like | 0.3421 | Inherited |
Nicotinic receptor ligand binding domain-like | 0.3545 | Inherited |
Ubiquitin-like | 0.3716 | Inherited |
Neurotransmitter-gated ion-channel transmembrane pore | 0.3906 | Inherited |
RNI-like | 0.3971 | Inherited |
HD-domain/PDEase-like | 0.3984 | Inherited |
FKBP-like | 0.3984 | Inherited |
Class II aaRS and biotin synthetases | 0.4143 | Inherited |
DHS-like NAD/FAD-binding domain | 0.4431 | Inherited |
Myosin rod fragments | 0.4431 | Inherited |
PRTase-like | 0.4431 | Inherited |
Hect, E3 ligase catalytic domain | 0.4431 | Inherited |
Ribosomal protein S5 domain 2-like | 0.4749 | Inherited |
Galactose-binding domain-like | 0.4749 | Inherited |
WW domain | 0.4789 | Inherited |
Sm-like ribonucleoproteins | 0.4789 | Inherited |
Cystine-knot cytokines | 0.4789 | Inherited |
SH2 domain | 0.4824 | Inherited |
Ferredoxin reductase-like, C-terminal NADP-linked domain | 0.4892 | Inherited |
Zinc beta-ribbon | 0.4892 | Inherited |
Calpain large subunit, middle domain (domain III) | 0.4892 | Inherited |
Riboflavin synthase domain-like | 0.4892 | Inherited |
FAD/NAD(P)-binding domain | 0.5006 | Inherited |
FAD-linked reductases, C-terminal domain | 0.5139 | Inherited |
Voltage-gated potassium channels | 0.5149 | Inherited |
Nucleotidylyl transferase | 0.5216 | Inherited |
SAM/Pointed domain | 0.5216 | Inherited |
SET domain | 0.5239 | Inherited |
UBC-like | 0.5239 | Inherited |
Seven-hairpin glycosidases | 0.5446 | Inherited |
Multidrug resistance efflux transporter EmrE | 0.55 | Inherited |
PLP-dependent transferases | 0.5676 | Inherited |
C2 domain (Calcium/lipid-binding domain, CaLB) | 0.5836 | Inherited |
KA1-like | 0.5996 | Inherited |
Nucleotide-binding domain | 0.5996 | Inherited |
Di-copper centre-containing domain | 0.5996 | Inherited |
HIT/MYND zinc finger-like | 0.6261 | Inherited |
S-adenosyl-L-methionine-dependent methyltransferases | 0.6272 | Inherited |
MFS general substrate transporter | 0.6647 | Inherited |
Frizzled cysteine-rich domain | 0.6648 | Inherited |
4Fe-4S ferredoxins | 0.6648 | Inherited |
S15/NS1 RNA-binding domain | 0.6648 | Inherited |
GST C-terminal domain-like | 0.6707 | Inherited |
alpha/beta-Hydrolases | 0.729 | Inherited |
EF-hand | 0.735 | Inherited |
Fibronectin type III | 0.7353 | Inherited |
ADC-like | 0.7358 | Inherited |
MIT domain | 0.7358 | Inherited |
Clavaminate synthase-like | 0.7895 | Inherited |
NAD kinase/diacylglycerol kinase-like | 0.7948 | Inherited |
CoA-dependent acyltransferases | 0.8028 | Inherited |
Cyclophilin-like | 0.8028 | Inherited |
UBA-like | 0.8141 | Inherited |
SNF-like | 0.8347 | Inherited |
Leucine zipper domain | 0.8406 | Inherited |
GTPase activation domain, GAP | 0.8492 | Inherited |
Eukaryotic type KH-domain (KH-domain type I) | 0.8492 | Inherited |
Thioredoxin-like | 0.8798 | Inherited |
Glucocorticoid receptor-like (DNA-binding domain) | 0.8892 | Inherited |
p53-like transcription factors | 0.8894 | Inherited |
Immunoglobulin | 0.8945 | Inherited |
Ribonuclease PH domain 2-like | 0.9179 | Inherited |
DNA/RNA polymerases | 0.9215 | Inherited |
Saposin | 0.9441 | Inherited |
Ribonuclease H-like | 0.961 | Inherited |
PAZ domain | 0.9799 | Inherited |
Ligand-binding domain in the NO signalling and Golgi transport | 0.9906 | Inherited |
Bet v1-like | 1 | Inherited |
B-box zinc-binding domain | 1 | Inherited |
Snake toxin-like | 1 | Inherited |
RING/U-box | 1 | Inherited |
Family A G protein-coupled receptor-like | 1 | Inherited |
Nuclear receptor ligand-binding domain | 1 | Inherited |
F-box domain | 1 | Inherited |
beta-beta-alpha zinc fingers | 1 | Inherited |
(show details)
Supra-domains annotated to this WP term (Not in SPWP)
Highlighted in gray are those with FDR>0.001
Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
56112,82615 56112 - Protein kinase-like (PK-like) 82615 - Polo-box domain | 0 | DIRECT |
82919,53300 82919 - Zn-finger domain of Sec23/24 53300 - vWA-like | 0 | DIRECT |
50156,50044 50156 - PDZ domain-like 50044 - SH3-domain | 0 | DIRECT |
81324,81296 81324 - Voltage-gated potassium channels 81296 - E set domains | 0 | DIRECT |
54236,47031 54236 - Ubiquitin-like 47031 - Second domain of FERM | 0 | DIRECT |
48179,48179 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | DIRECT |
56176,55103 56176 - FAD-binding/transporter-associated domain-like 55103 - FAD-linked oxidases, C-terminal domain | 0 | DIRECT |
51905,56425 51905 - FAD/NAD(P)-binding domain 56425 - Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | DIRECT |
161093,161093 161093 - MgtE membrane domain-like 161093 - MgtE membrane domain-like | 0 | DIRECT |
52540,90123 52540 - P-loop containing nucleoside triphosphate hydrolases 90123 - ABC transporter transmembrane region | 0 | DIRECT |
51445,51011 51445 - (Trans)glycosidases 51011 - Glycosyl hydrolase domain | 0 | DIRECT |
50249,50249 50249 - Nucleic acid-binding proteins 50249 - Nucleic acid-binding proteins | 0 | DIRECT |
48334,52540 48334 - DNA repair protein MutS, domain III 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
141739,141739 141739 - MFPT repeat-like 141739 - MFPT repeat-like | 0 | DIRECT |
74788,75632 74788 - Cullin repeat-like 75632 - Cullin homology domain | 0 | DIRECT |
54495,46934 54495 - UBC-like 46934 - UBA-like | 0 | DIRECT |
46966,46966 46966 - Spectrin repeat 46966 - Spectrin repeat | 0 | DIRECT |
54695,81382 54695 - POZ domain 81382 - Skp1 dimerisation domain-like | 0 | DIRECT |
48371,56112 48371 - ARM repeat 56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
57196,63825 57196 - EGF/Laminin 63825 - YWTD domain | 0 | DIRECT |
51735,56327 51735 - NAD(P)-binding Rossmann-fold domains 56327 - LDH C-terminal domain-like | 0 | DIRECT |
52490,55307 52490 - Tubulin nucleotide-binding domain-like 55307 - Tubulin C-terminal domain-like | 0 | DIRECT |
64356,49447 64356 - SNARE-like 49447 - Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
46938,52087 46938 - CRAL/TRIO N-terminal domain 52087 - CRAL/TRIO domain | 0 | DIRECT |
53738,55957 53738 - Phosphoglucomutase, first 3 domains 55957 - Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
48065,50729 48065 - DBL homology domain (DH-domain) 50729 - PH domain-like | 0 | DIRECT |
56091,50249 56091 - DNA ligase/mRNA capping enzyme, catalytic domain 50249 - Nucleic acid-binding proteins | 0 | DIRECT |
56112,48371 56112 - Protein kinase-like (PK-like) 48371 - ARM repeat | 0 | DIRECT |
52540,81271 52540 - P-loop containing nucleoside triphosphate hydrolases 81271 - TGS-like | 0 | DIRECT |
64593,74853 64593 - Intermediate filament protein, coiled coil region 74853 - Lamin A/C globular tail domain | 0 | DIRECT |
52113,52113 52113 - BRCT domain 52113 - BRCT domain | 0 | DIRECT |
52374,47323 52374 - Nucleotidylyl transferase 47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
50729,47473 50729 - PH domain-like 47473 - EF-hand | 0 | DIRECT |
57889,50729 57889 - Cysteine-rich domain 50729 - PH domain-like | 0 | DIRECT |
57903,82199 57903 - FYVE/PHD zinc finger 82199 - SET domain | 0 | DIRECT |
51206,51206 51206 - cAMP-binding domain-like 51206 - cAMP-binding domain-like | 0 | DIRECT |
47031,50729 47031 - Second domain of FERM 50729 - PH domain-like | 0 | DIRECT |
47473,51695 47473 - EF-hand 51695 - PLC-like phosphodiesterases | 0 | DIRECT |
47741,56176 47741 - CO dehydrogenase ISP C-domain like 56176 - FAD-binding/transporter-associated domain-like | 0 | DIRECT |
55486,57552 55486 - Metalloproteases ("zincins"), catalytic domain 57552 - Blood coagulation inhibitor (disintegrin) | 0 | DIRECT |
55874,54211 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 54211 - Ribosomal protein S5 domain 2-like | 0 | DIRECT |
52743,49785 52743 - Subtilisin-like 49785 - Galactose-binding domain-like | 0 | DIRECT |
54211,55060 54211 - Ribosomal protein S5 domain 2-like 55060 - GHMP Kinase, C-terminal domain | 0 | DIRECT |
49742,49742 49742 - PHM/PNGase F 49742 - PHM/PNGase F | 0 | DIRECT |
47954,47954 47954 - Cyclin-like 47954 - Cyclin-like | 0 | DIRECT |
52518,52922 52518 - Thiamin diphosphate-binding fold (THDP-binding) 52922 - TK C-terminal domain-like | 0 | DIRECT |
48371,48371 48371 - ARM repeat 48371 - ARM repeat | 0 | DIRECT |
47576,47576 47576 - Calponin-homology domain, CH-domain 47576 - Calponin-homology domain, CH-domain | 0 | DIRECT |
82615,82615 82615 - Polo-box domain 82615 - Polo-box domain | 0 | DIRECT |
55973,55973 55973 - S-adenosylmethionine synthetase 55973 - S-adenosylmethionine synthetase | 0 | DIRECT |
55785,55785 55785 - PYP-like sensor domain (PAS domain) 55785 - PYP-like sensor domain (PAS domain) | 0 | DIRECT |
53901,53901 53901 - Thiolase-like 53901 - Thiolase-like | 0 | DIRECT |
57362,57362 57362 - BPTI-like 57362 - BPTI-like | 0 | DIRECT |
56968,48431 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions 48431 - Lipovitellin-phosvitin complex, superhelical domain | 0 | DIRECT |
56059,52210 56059 - Glutathione synthetase ATP-binding domain-like 52210 - Succinyl-CoA synthetase domains | 0 | DIRECT |
68923,53795 68923 - PEP carboxykinase N-terminal domain 53795 - PEP carboxykinase-like | 0 | DIRECT |
52047,52047 52047 - RNI-like 52047 - RNI-like | 0 | DIRECT |
52440,56059 52440 - PreATP-grasp domain 56059 - Glutathione synthetase ATP-binding domain-like | 0 | DIRECT |
50677,52374 50677 - ValRS/IleRS/LeuRS editing domain 52374 - Nucleotidylyl transferase | 0 | DIRECT |
57196,49899 57196 - EGF/Laminin 49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
52540,46785 52540 - P-loop containing nucleoside triphosphate hydrolases 46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
82895,82895 82895 - TSP-1 type 1 repeat 82895 - TSP-1 type 1 repeat | 0 | DIRECT |
81301,81631 81301 - Nucleotidyltransferase 81631 - PAP/OAS1 substrate-binding domain | 0 | DIRECT |
50692,54585 50692 - ADC-like 54585 - Cdc48 domain 2-like | 0 | DIRECT |
54001,49758 54001 - Cysteine proteinases 49758 - Calpain large subunit, middle domain (domain III) | 0 | DIRECT |
57535,57535 57535 - Complement control module/SCR domain 57535 - Complement control module/SCR domain | 0 | DIRECT |
57863,48403 57863 - ArfGap/RecO-like zinc finger 48403 - Ankyrin repeat | 0 | DIRECT |
51971,54373 51971 - Nucleotide-binding domain 54373 - FAD-linked reductases, C-terminal domain | 0 | DIRECT |
47769,47769 47769 - SAM/Pointed domain 47769 - SAM/Pointed domain | 0 | DIRECT |
81383,52047 81383 - F-box domain 52047 - RNI-like | 0 | DIRECT |
81698,81698 81698 - FF domain 81698 - FF domain | 0 | DIRECT |
53067,100920 53067 - Actin-like ATPase domain 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
48592,54849 48592 - GroEL equatorial domain-like 54849 - GroEL-intermediate domain like | 0 | DIRECT |
57184,57196 57184 - Growth factor receptor domain 57196 - EGF/Laminin | 0 | DIRECT |
51338,51556 51338 - Composite domain of metallo-dependent hydrolases 51556 - Metallo-dependent hydrolases | 0 | DIRECT |
47413,46689 47413 - lambda repressor-like DNA-binding domains 46689 - Homeodomain-like | 0 | DIRECT |
50044,50044 50044 - SH3-domain 50044 - SH3-domain | 0 | DIRECT |
57414,57414 57414 - Hairpin loop containing domain-like 57414 - Hairpin loop containing domain-like | 0 | DIRECT |
55729,55729 55729 - Acyl-CoA N-acyltransferases (Nat) 55729 - Acyl-CoA N-acyltransferases (Nat) | 0 | DIRECT |
55486,50923 55486 - Metalloproteases ("zincins"), catalytic domain 50923 - Hemopexin-like domain | 0 | DIRECT |
51445,54556 51445 - (Trans)glycosidases 54556 - Chitinase insertion domain | 0 | DIRECT |
51905,55424 51905 - FAD/NAD(P)-binding domain 55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | DIRECT |
50729,56112 50729 - PH domain-like 56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
49493,49493 49493 - HSP40/DnaJ peptide-binding domain 49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
47895,52540 47895 - Transducin (alpha subunit), insertion domain 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
88713,88688 88713 - Glycoside hydrolase/deacetylase 88688 - Families 57/38 glycoside transferase middle domain | 0 | DIRECT |
56645,47203 56645 - Acyl-CoA dehydrogenase NM domain-like 47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
100950,100950 100950 - NagB/RpiA/CoA transferase-like 100950 - NagB/RpiA/CoA transferase-like | 0 | DIRECT |
48431,56968 48431 - Lipovitellin-phosvitin complex, superhelical domain 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | DIRECT |
52540,47917 52540 - P-loop containing nucleoside triphosphate hydrolases 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
54160,52540 54160 - Chromo domain-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
51695,49562 51695 - PLC-like phosphodiesterases 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
90229,90229 90229 - CCCH zinc finger 90229 - CCCH zinc finger | 0 | DIRECT |
75632,46785 75632 - Cullin homology domain 46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
48425,50729 48425 - Sec7 domain 50729 - PH domain-like | 0 | DIRECT |
49313,49313 49313 - Cadherin-like 49313 - Cadherin-like | 0 | DIRECT |
46785,46785 46785 - "Winged helix" DNA-binding domain 46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
57889,48350 57889 - Cysteine-rich domain 48350 - GTPase activation domain, GAP | 0 | DIRECT |
55326,56042 55326 - PurM N-terminal domain-like 56042 - PurM C-terminal domain-like | 0 | DIRECT |
49265,48726 49265 - Fibronectin type III 48726 - Immunoglobulin | 0 | DIRECT |
49562,48371 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) 48371 - ARM repeat | 0 | DIRECT |
47203,47203 47203 - Acyl-CoA dehydrogenase C-terminal domain-like 47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
53738,53738 53738 - Phosphoglucomutase, first 3 domains 53738 - Phosphoglucomutase, first 3 domains | 0 | DIRECT |
53187,49464 53187 - Zn-dependent exopeptidases 49464 - Carboxypeptidase regulatory domain-like | 0 | DIRECT |
51735,55347 51735 - NAD(P)-binding Rossmann-fold domains 55347 - Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | DIRECT |
81383,50978 81383 - F-box domain 50978 - WD40 repeat-like | 0 | DIRECT |
52518,52518 52518 - Thiamin diphosphate-binding fold (THDP-binding) 52518 - Thiamin diphosphate-binding fold (THDP-binding) | 0 | DIRECT |
54897,53187 54897 - Protease propeptides/inhibitors 53187 - Zn-dependent exopeptidases | 0 | DIRECT |
57196,57184 57196 - EGF/Laminin 57184 - Growth factor receptor domain | 0 | DIRECT |
47587,56399 47587 - Domain of poly(ADP-ribose) polymerase 56399 - ADP-ribosylation | 0 | DIRECT |
54534,54534 54534 - FKBP-like 54534 - FKBP-like | 0 | DIRECT |
144232,82199 144232 - HIT/MYND zinc finger-like 82199 - SET domain | 0 | DIRECT |
50129,51735 50129 - GroES-like 51735 - NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
54160,54160 54160 - Chromo domain-like 54160 - Chromo domain-like | 0 | DIRECT |
48403,52151 48403 - Ankyrin repeat 52151 - FabD/lysophospholipase-like | 0 | DIRECT |
81324,53850 81324 - Voltage-gated potassium channels 53850 - Periplasmic binding protein-like II | 0 | DIRECT |
48464,89009 48464 - ENTH/VHS domain 89009 - GAT-like domain | 0 | DIRECT |
74650,51445 74650 - Galactose mutarotase-like 51445 - (Trans)glycosidases | 0 | DIRECT |
53187,55031 53187 - Zn-dependent exopeptidases 55031 - Bacterial exopeptidase dimerisation domain | 0 | DIRECT |
47473,103506 47473 - EF-hand 103506 - Mitochondrial carrier | 0 | DIRECT |
54236,54236 54236 - Ubiquitin-like 54236 - Ubiquitin-like | 0 | DIRECT |
81333,81333 81333 - F1F0 ATP synthase subunit C 81333 - F1F0 ATP synthase subunit C | 0 | DIRECT |
57756,57756 57756 - Retrovirus zinc finger-like domains 57756 - Retrovirus zinc finger-like domains | 0 | DIRECT |
56601,48403 56601 - beta-lactamase/transpeptidase-like 48403 - Ankyrin repeat | 0 | DIRECT |
54665,56003 54665 - CO dehydrogenase molybdoprotein N-domain-like 56003 - Molybdenum cofactor-binding domain | 0 | DIRECT |
54897,52743 54897 - Protease propeptides/inhibitors 52743 - Subtilisin-like | 0 | DIRECT |
54849,52029 54849 - GroEL-intermediate domain like 52029 - GroEL apical domain-like | 0 | DIRECT |
53067,53067 53067 - Actin-like ATPase domain 53067 - Actin-like ATPase domain | 0 | DIRECT |
52283,51735 52283 - Formate/glycerate dehydrogenase catalytic domain-like 51735 - NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
100920,100934 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
161111,160240 161111 - Cation efflux protein transmembrane domain-like 160240 - Cation efflux protein cytoplasmic domain-like | 0 | DIRECT |
141673,50800 141673 - MOSC N-terminal domain-like 50800 - PK beta-barrel domain-like | 0 | DIRECT |
47220,47220 47220 - alpha-catenin/vinculin-like 47220 - alpha-catenin/vinculin-like | 0 | DIRECT |
50447,50465 50447 - Translation proteins 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
57938,49493 57938 - DnaJ/Hsp40 cysteine-rich domain 49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
54768,54768 54768 - dsRNA-binding domain-like 54768 - dsRNA-binding domain-like | 0 | DIRECT |
55681,52954 55681 - Class II aaRS and biotin synthetases 52954 - Class II aaRS ABD-related | 0 | DIRECT |
52540,140990 52540 - P-loop containing nucleoside triphosphate hydrolases 140990 - FtsH protease domain-like | 0 | DIRECT |
49348,55711 49348 - Clathrin adaptor appendage domain 55711 - Subdomain of clathrin and coatomer appendage domain | 0 | DIRECT |
54292,47741 54292 - 2Fe-2S ferredoxin-like 47741 - CO dehydrogenase ISP C-domain like | 0 | DIRECT |
57184,57184 57184 - Growth factor receptor domain 57184 - Growth factor receptor domain | 0 | DIRECT |
51556,51338 51556 - Metallo-dependent hydrolases 51338 - Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
57889,57889 57889 - Cysteine-rich domain 57889 - Cysteine-rich domain | 0 | DIRECT |
50044,52540 50044 - SH3-domain 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
47090,55486 47090 - PGBD-like 55486 - Metalloproteases ("zincins"), catalytic domain | 0 | DIRECT |
57903,51197 57903 - FYVE/PHD zinc finger 51197 - Clavaminate synthase-like | 0 | DIRECT |
54585,52540 54585 - Cdc48 domain 2-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
81811,82754 81811 - Helical domain of Sec23/24 82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
55920,46785 55920 - Creatinase/aminopeptidase 46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
81324,81327 81324 - Voltage-gated potassium channels 81327 - Small-conductance potassium channel | 0 | DIRECT |
50978,50998 50978 - WD40 repeat-like 50998 - Quinoprotein alcohol dehydrogenase-like | 0 | DIRECT |
57850,117839 57850 - RING/U-box 117839 - WWE domain | 0 | DIRECT |
56672,100879 56672 - DNA/RNA polymerases 100879 - Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
55394,55394 55394 - Bactericidal permeability-increasing protein, BPI 55394 - Bactericidal permeability-increasing protein, BPI | 0 | DIRECT |
56059,51246 56059 - Glutathione synthetase ATP-binding domain-like 51246 - Rudiment single hybrid motif | 0 | DIRECT |
57625,57625 57625 - Invertebrate chitin-binding proteins 57625 - Invertebrate chitin-binding proteins | 0 | DIRECT |
90123,52540 90123 - ABC transporter transmembrane region 52540 - P-loop containing nucleoside triphosphate hydrolases | 0.01707 | INHERITED FROM: colchicine hypersensitive || organism environmental stimulus response variant || metal response variant || cadmium response variant || RNAi response variant || RNAi resistant |
52540,52540 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0.07493 | INHERITED FROM: organism stress response variant || organism UV response variant || dauer lifespan variant || organism environmental stimulus response variant || dauer lifespan extended || sick |
48452,48452 48452 - TPR-like 48452 - TPR-like | 0.09584 | INHERITED FROM: gene expression variant || aqueous chemosensory response variant || positive chemotaxis defective || organism environmental stimulus response variant || chemical response variant || ivermectin response variant || antihelmintic response variant || dauer defective || aldicarb response variant || pattern of transgene expression variant |
56112,55073 56112 - Protein kinase-like (PK-like) 55073 - Nucleotide cyclase | 0.1201 | INHERITED FROM: benzaldehyde chemotaxis variant || lithium chemotaxis defective || iodide chemotaxis defective || chemotaxis variant || aqueous chemosensory response variant || organism environmental stimulus response variant || magnesium chemotaxis defective || cation positive chemotaxis variant || alkaline pH chemotaxis variant || cation positive chemotaxis defective || chemical response variant || AWC odorant chemotaxis defective || anion positive chemotaxis defective || anion positive chemotaxis variant || chemosensory response variant || AWC odorant chemotaxis variant || bromide chemotaxis defective || iodide chemotaxis variant || chemosensory behavior variant || bromide chemotaxis variant || positive chemotaxis variant |
81660,56784 81660 - Metal cation-transporting ATPase, ATP-binding domain N 56784 - HAD-like | 0.1201 | INHERITED FROM: organism environmental stimulus response variant || nicotine hypersensitive || lipid composition variant |
56436,56436 56436 - C-type lectin-like 56436 - C-type lectin-like | 0.129 | INHERITED FROM: cadmium response variant |
52540,50447 52540 - P-loop containing nucleoside triphosphate hydrolases 50447 - Translation proteins | 0.1875 | INHERITED FROM: mRNA levels reduced || protein phosphorylation variant || mRNA levels increased || transgene expression variant || protein aggregation variant || proteasome core activity variant || protein protein interaction variant || protein phosphorylation increased |
56436,49854 56436 - C-type lectin-like 49854 - Spermadhesin, CUB domain | 0.2192 | INHERITED FROM: cadmium response variant || cadmium hypersensitive |
51735,48179 51735 - NAD(P)-binding Rossmann-fold domains 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0.2334 | INHERITED FROM: lipid metabolism variant || fat content variant |
56784,81665 56784 - HAD-like 81665 - Calcium ATPase, transmembrane domain M | 0.2334 | INHERITED FROM: organism environmental stimulus response variant || nicotine hypersensitive |
52833,52833 52833 - Thioredoxin-like 52833 - Thioredoxin-like | 0.2902 | INHERITED FROM: protein interaction variant || protein aggregation variant || protein protein interaction variant || pattern of transgene expression variant |
50978,50978 50978 - WD40 repeat-like 50978 - WD40 repeat-like | 0.2902 | INHERITED FROM: pesticide response variant || ivermectin resistant || chemotaxis variant || aqueous positive chemotaxis defective || aqueous chemosensory response variant || positive chemotaxis defective || negative chemotaxis variant || drug resistant || odorant chemosensory response variant || ivermectin response variant || chemosensory response variant || dauer defective || chemosensory behavior variant || aqueous positive chemotaxis variant || osmotic avoidance variant || mechanosensation variant || positive chemotaxis variant |
47473,47473 47473 - EF-hand 47473 - EF-hand | 0.3231 | INHERITED FROM: drug response variant || acetylcholinesterase inhibitor response variant || aldicarb response variant |
54928,54928 54928 - RNA-binding domain, RBD 54928 - RNA-binding domain, RBD | 0.3304 | INHERITED FROM: RNA metabolism variant || gene expression variant || organism starvation response variant || late larval arrest || starvation induced apoptosis variant |
63712,90112 63712 - Nicotinic receptor ligand binding domain-like 90112 - Neurotransmitter-gated ion-channel transmembrane pore | 0.3906 | INHERITED FROM: benzaldehyde chemotaxis variant || drug response variant || chemotaxis variant || hypoosmotic shock hypersensitive || organism environmental stimulus response variant || DMPP response variant || chemical response variant || organism temperature response variant || selenium response variant || nicotine resistant || cholinergic agonist resistant || chemosensory response variant || AWC odorant chemotaxis variant || antihelmintic response variant || sodium chloride chemotaxis variant || thermosensory behavior variant || chemosensory behavior variant || mechanosensation variant || slowing response on food variant || positive chemotaxis variant |
57716,57716 57716 - Glucocorticoid receptor-like (DNA-binding domain) 57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0.4474 | INHERITED FROM: protein expression variant || protein expression reduced || organism metabolism processing variant |
52833,47616 52833 - Thioredoxin-like 47616 - GST C-terminal domain-like | 0.5016 | INHERITED FROM: organism stress response variant || organism environmental stimulus response variant || metal response variant || organism heat hypersensitive || paraquat response variant || enzyme activity reduced || organism electrophilic stress hypersensitive || enzyme activity variant || cadmium hypersensitive |
101690,53098 101690 - PAZ domain 53098 - Ribonuclease H-like | 0.5446 | INHERITED FROM: RNA expression variant || gene expression variant || maintenance of gene silencing variant || RNAi response variant || 21U RNA expression variant |
90257,90257 90257 - Myosin rod fragments 90257 - Myosin rod fragments | 0.5446 | INHERITED FROM: hermaphrodite physiology variant || sexually dimorphic physiology variant |
50044,55550 50044 - SH3-domain 55550 - SH2 domain | 0.5446 | INHERITED FROM: protein expression reduced |
51045,51045 51045 - WW domain 51045 - WW domain | 0.5996 | INHERITED FROM: transgene expression variant |
57903,57903 57903 - FYVE/PHD zinc finger 57903 - FYVE/PHD zinc finger | 0.6648 | INHERITED FROM: organism UV response variant || organism UV hypersensitive |
50249,55681 50249 - Nucleic acid-binding proteins 55681 - Class II aaRS and biotin synthetases | 0.6648 | INHERITED FROM: transgene expression increased |
51905,54373 51905 - FAD/NAD(P)-binding domain 54373 - FAD-linked reductases, C-terminal domain | 0.667 | INHERITED FROM: shortened life span || life span variant |
57196,57196 57196 - EGF/Laminin 57196 - EGF/Laminin | 0.6809 | INHERITED FROM: protein expression reduced |
55550,50044 55550 - SH2 domain 50044 - SH3-domain | 0.7358 | INHERITED FROM: protein expression variant || level of protein expression variant || protein expression reduced |
57716,48508 57716 - Glucocorticoid receptor-like (DNA-binding domain) 48508 - Nuclear receptor ligand-binding domain | 0.766 | INHERITED FROM: SDS sensitive dauer || chemical hypersensitive || dauer resistance to harsh conditions variant |
48726,49265 48726 - Immunoglobulin 49265 - Fibronectin type III | 0.8028 | INHERITED FROM: growth rate variant || aldicarb resistant || chemical response variant || protein degradation variant |
48726,48726 48726 - Immunoglobulin 48726 - Immunoglobulin | 0.8376 | INHERITED FROM: growth rate variant || protein degradation variant |
54211,55666 54211 - Ribosomal protein S5 domain 2-like 55666 - Ribonuclease PH domain 2-like | 0.9179 | INHERITED FROM: early larval arrest |
49562,49562 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0.9215 | INHERITED FROM: drug resistant |
52777,52777 52777 - CoA-dependent acyltransferases 52777 - CoA-dependent acyltransferases | 0.9472 | INHERITED FROM: lipid metabolism variant || fat content variant |
49785,49785 49785 - Galactose-binding domain-like 49785 - Galactose-binding domain-like | 0.9472 | INHERITED FROM: protein interaction variant || protein aggregation variant || protein protein interaction variant |
57850,57845 57850 - RING/U-box 57845 - B-box zinc-binding domain | 1 | INHERITED FROM: protein interaction variant || protein aggregation variant || transgene subcellular localization variant || protein protein interaction variant |
57850,57850 57850 - RING/U-box 57850 - RING/U-box | 1 | INHERITED FROM: protein interaction variant || protein aggregation variant || transgene subcellular localization variant || protein protein interaction variant |
53300,56436 53300 - vWA-like 56436 - C-type lectin-like | 1 | INHERITED FROM: pathogen susceptibility increased || pathogen induced death increased |
Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
56112,82615 56112 - Protein kinase-like (PK-like) 82615 - Polo-box domain | 0 | Direct |
82919,53300 82919 - Zn-finger domain of Sec23/24 53300 - vWA-like | 0 | Direct |
50156,50044 50156 - PDZ domain-like 50044 - SH3-domain | 0 | Direct |
81324,81296 81324 - Voltage-gated potassium channels 81296 - E set domains | 0 | Direct |
54236,47031 54236 - Ubiquitin-like 47031 - Second domain of FERM | 0 | Direct |
48179,48179 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | Direct |
56176,55103 56176 - FAD-binding/transporter-associated domain-like 55103 - FAD-linked oxidases, C-terminal domain | 0 | Direct |
51905,56425 51905 - FAD/NAD(P)-binding domain 56425 - Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | Direct |
161093,161093 161093 - MgtE membrane domain-like 161093 - MgtE membrane domain-like | 0 | Direct |
52540,90123 52540 - P-loop containing nucleoside triphosphate hydrolases 90123 - ABC transporter transmembrane region | 0 | Direct |
51445,51011 51445 - (Trans)glycosidases 51011 - Glycosyl hydrolase domain | 0 | Direct |
50249,50249 50249 - Nucleic acid-binding proteins 50249 - Nucleic acid-binding proteins | 0 | Direct |
48334,52540 48334 - DNA repair protein MutS, domain III 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
141739,141739 141739 - MFPT repeat-like 141739 - MFPT repeat-like | 0 | Direct |
74788,75632 74788 - Cullin repeat-like 75632 - Cullin homology domain | 0 | Direct |
54495,46934 54495 - UBC-like 46934 - UBA-like | 0 | Direct |
46966,46966 46966 - Spectrin repeat 46966 - Spectrin repeat | 0 | Direct |
54695,81382 54695 - POZ domain 81382 - Skp1 dimerisation domain-like | 0 | Direct |
48371,56112 48371 - ARM repeat 56112 - Protein kinase-like (PK-like) | 0 | Direct |
57196,63825 57196 - EGF/Laminin 63825 - YWTD domain | 0 | Direct |
51735,56327 51735 - NAD(P)-binding Rossmann-fold domains 56327 - LDH C-terminal domain-like | 0 | Direct |
52490,55307 52490 - Tubulin nucleotide-binding domain-like 55307 - Tubulin C-terminal domain-like | 0 | Direct |
64356,49447 64356 - SNARE-like 49447 - Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
46938,52087 46938 - CRAL/TRIO N-terminal domain 52087 - CRAL/TRIO domain | 0 | Direct |
53738,55957 53738 - Phosphoglucomutase, first 3 domains 55957 - Phosphoglucomutase, C-terminal domain | 0 | Direct |
48065,50729 48065 - DBL homology domain (DH-domain) 50729 - PH domain-like | 0 | Direct |
56091,50249 56091 - DNA ligase/mRNA capping enzyme, catalytic domain 50249 - Nucleic acid-binding proteins | 0 | Direct |
56112,48371 56112 - Protein kinase-like (PK-like) 48371 - ARM repeat | 0 | Direct |
52540,81271 52540 - P-loop containing nucleoside triphosphate hydrolases 81271 - TGS-like | 0 | Direct |
64593,74853 64593 - Intermediate filament protein, coiled coil region 74853 - Lamin A/C globular tail domain | 0 | Direct |
52113,52113 52113 - BRCT domain 52113 - BRCT domain | 0 | Direct |
52374,47323 52374 - Nucleotidylyl transferase 47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
50729,47473 50729 - PH domain-like 47473 - EF-hand | 0 | Direct |
57889,50729 57889 - Cysteine-rich domain 50729 - PH domain-like | 0 | Direct |
57903,82199 57903 - FYVE/PHD zinc finger 82199 - SET domain | 0 | Direct |
51206,51206 51206 - cAMP-binding domain-like 51206 - cAMP-binding domain-like | 0 | Direct |
47031,50729 47031 - Second domain of FERM 50729 - PH domain-like | 0 | Direct |
47473,51695 47473 - EF-hand 51695 - PLC-like phosphodiesterases | 0 | Direct |
47741,56176 47741 - CO dehydrogenase ISP C-domain like 56176 - FAD-binding/transporter-associated domain-like | 0 | Direct |
55486,57552 55486 - Metalloproteases ("zincins"), catalytic domain 57552 - Blood coagulation inhibitor (disintegrin) | 0 | Direct |
55874,54211 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 54211 - Ribosomal protein S5 domain 2-like | 0 | Direct |
52743,49785 52743 - Subtilisin-like 49785 - Galactose-binding domain-like | 0 | Direct |
54211,55060 54211 - Ribosomal protein S5 domain 2-like 55060 - GHMP Kinase, C-terminal domain | 0 | Direct |
49742,49742 49742 - PHM/PNGase F 49742 - PHM/PNGase F | 0 | Direct |
47954,47954 47954 - Cyclin-like 47954 - Cyclin-like | 0 | Direct |
52518,52922 52518 - Thiamin diphosphate-binding fold (THDP-binding) 52922 - TK C-terminal domain-like | 0 | Direct |
48371,48371 48371 - ARM repeat 48371 - ARM repeat | 0 | Direct |
47576,47576 47576 - Calponin-homology domain, CH-domain 47576 - Calponin-homology domain, CH-domain | 0 | Direct |
82615,82615 82615 - Polo-box domain 82615 - Polo-box domain | 0 | Direct |
55973,55973 55973 - S-adenosylmethionine synthetase 55973 - S-adenosylmethionine synthetase | 0 | Direct |
55785,55785 55785 - PYP-like sensor domain (PAS domain) 55785 - PYP-like sensor domain (PAS domain) | 0 | Direct |
53901,53901 53901 - Thiolase-like 53901 - Thiolase-like | 0 | Direct |
57362,57362 57362 - BPTI-like 57362 - BPTI-like | 0 | Direct |
56968,48431 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions 48431 - Lipovitellin-phosvitin complex, superhelical domain | 0 | Direct |
56059,52210 56059 - Glutathione synthetase ATP-binding domain-like 52210 - Succinyl-CoA synthetase domains | 0 | Direct |
68923,53795 68923 - PEP carboxykinase N-terminal domain 53795 - PEP carboxykinase-like | 0 | Direct |
52047,52047 52047 - RNI-like 52047 - RNI-like | 0 | Direct |
52440,56059 52440 - PreATP-grasp domain 56059 - Glutathione synthetase ATP-binding domain-like | 0 | Direct |
50677,52374 50677 - ValRS/IleRS/LeuRS editing domain 52374 - Nucleotidylyl transferase | 0 | Direct |
57196,49899 57196 - EGF/Laminin 49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
52540,46785 52540 - P-loop containing nucleoside triphosphate hydrolases 46785 - "Winged helix" DNA-binding domain | 0 | Direct |
82895,82895 82895 - TSP-1 type 1 repeat 82895 - TSP-1 type 1 repeat | 0 | Direct |
81301,81631 81301 - Nucleotidyltransferase 81631 - PAP/OAS1 substrate-binding domain | 0 | Direct |
50692,54585 50692 - ADC-like 54585 - Cdc48 domain 2-like | 0 | Direct |
54001,49758 54001 - Cysteine proteinases 49758 - Calpain large subunit, middle domain (domain III) | 0 | Direct |
57535,57535 57535 - Complement control module/SCR domain 57535 - Complement control module/SCR domain | 0 | Direct |
57863,48403 57863 - ArfGap/RecO-like zinc finger 48403 - Ankyrin repeat | 0 | Direct |
51971,54373 51971 - Nucleotide-binding domain 54373 - FAD-linked reductases, C-terminal domain | 0 | Direct |
47769,47769 47769 - SAM/Pointed domain 47769 - SAM/Pointed domain | 0 | Direct |
81383,52047 81383 - F-box domain 52047 - RNI-like | 0 | Direct |
81698,81698 81698 - FF domain 81698 - FF domain | 0 | Direct |
53067,100920 53067 - Actin-like ATPase domain 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
48592,54849 48592 - GroEL equatorial domain-like 54849 - GroEL-intermediate domain like | 0 | Direct |
57184,57196 57184 - Growth factor receptor domain 57196 - EGF/Laminin | 0 | Direct |
51338,51556 51338 - Composite domain of metallo-dependent hydrolases 51556 - Metallo-dependent hydrolases | 0 | Direct |
47413,46689 47413 - lambda repressor-like DNA-binding domains 46689 - Homeodomain-like | 0 | Direct |
50044,50044 50044 - SH3-domain 50044 - SH3-domain | 0 | Direct |
57414,57414 57414 - Hairpin loop containing domain-like 57414 - Hairpin loop containing domain-like | 0 | Direct |
55729,55729 55729 - Acyl-CoA N-acyltransferases (Nat) 55729 - Acyl-CoA N-acyltransferases (Nat) | 0 | Direct |
55486,50923 55486 - Metalloproteases ("zincins"), catalytic domain 50923 - Hemopexin-like domain | 0 | Direct |
51445,54556 51445 - (Trans)glycosidases 54556 - Chitinase insertion domain | 0 | Direct |
51905,55424 51905 - FAD/NAD(P)-binding domain 55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | Direct |
50729,56112 50729 - PH domain-like 56112 - Protein kinase-like (PK-like) | 0 | Direct |
49493,49493 49493 - HSP40/DnaJ peptide-binding domain 49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
47895,52540 47895 - Transducin (alpha subunit), insertion domain 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
88713,88688 88713 - Glycoside hydrolase/deacetylase 88688 - Families 57/38 glycoside transferase middle domain | 0 | Direct |
56645,47203 56645 - Acyl-CoA dehydrogenase NM domain-like 47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
100950,100950 100950 - NagB/RpiA/CoA transferase-like 100950 - NagB/RpiA/CoA transferase-like | 0 | Direct |
48431,56968 48431 - Lipovitellin-phosvitin complex, superhelical domain 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | Direct |
52540,47917 52540 - P-loop containing nucleoside triphosphate hydrolases 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
54160,52540 54160 - Chromo domain-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
51695,49562 51695 - PLC-like phosphodiesterases 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
90229,90229 90229 - CCCH zinc finger 90229 - CCCH zinc finger | 0 | Direct |
75632,46785 75632 - Cullin homology domain 46785 - "Winged helix" DNA-binding domain | 0 | Direct |
48425,50729 48425 - Sec7 domain 50729 - PH domain-like | 0 | Direct |
49313,49313 49313 - Cadherin-like 49313 - Cadherin-like | 0 | Direct |
46785,46785 46785 - "Winged helix" DNA-binding domain 46785 - "Winged helix" DNA-binding domain | 0 | Direct |
57889,48350 57889 - Cysteine-rich domain 48350 - GTPase activation domain, GAP | 0 | Direct |
55326,56042 55326 - PurM N-terminal domain-like 56042 - PurM C-terminal domain-like | 0 | Direct |
49265,48726 49265 - Fibronectin type III 48726 - Immunoglobulin | 0 | Direct |
49562,48371 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) 48371 - ARM repeat | 0 | Direct |
47203,47203 47203 - Acyl-CoA dehydrogenase C-terminal domain-like 47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
53738,53738 53738 - Phosphoglucomutase, first 3 domains 53738 - Phosphoglucomutase, first 3 domains | 0 | Direct |
53187,49464 53187 - Zn-dependent exopeptidases 49464 - Carboxypeptidase regulatory domain-like | 0 | Direct |
51735,55347 51735 - NAD(P)-binding Rossmann-fold domains 55347 - Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | Direct |
81383,50978 81383 - F-box domain 50978 - WD40 repeat-like | 0 | Direct |
52518,52518 52518 - Thiamin diphosphate-binding fold (THDP-binding) 52518 - Thiamin diphosphate-binding fold (THDP-binding) | 0 | Direct |
54897,53187 54897 - Protease propeptides/inhibitors 53187 - Zn-dependent exopeptidases | 0 | Direct |
57196,57184 57196 - EGF/Laminin 57184 - Growth factor receptor domain | 0 | Direct |
47587,56399 47587 - Domain of poly(ADP-ribose) polymerase 56399 - ADP-ribosylation | 0 | Direct |
54534,54534 54534 - FKBP-like 54534 - FKBP-like | 0 | Direct |
144232,82199 144232 - HIT/MYND zinc finger-like 82199 - SET domain | 0 | Direct |
50129,51735 50129 - GroES-like 51735 - NAD(P)-binding Rossmann-fold domains | 0 | Direct |
54160,54160 54160 - Chromo domain-like 54160 - Chromo domain-like | 0 | Direct |
48403,52151 48403 - Ankyrin repeat 52151 - FabD/lysophospholipase-like | 0 | Direct |
81324,53850 81324 - Voltage-gated potassium channels 53850 - Periplasmic binding protein-like II | 0 | Direct |
48464,89009 48464 - ENTH/VHS domain 89009 - GAT-like domain | 0 | Direct |
74650,51445 74650 - Galactose mutarotase-like 51445 - (Trans)glycosidases | 0 | Direct |
53187,55031 53187 - Zn-dependent exopeptidases 55031 - Bacterial exopeptidase dimerisation domain | 0 | Direct |
47473,103506 47473 - EF-hand 103506 - Mitochondrial carrier | 0 | Direct |
54236,54236 54236 - Ubiquitin-like 54236 - Ubiquitin-like | 0 | Direct |
81333,81333 81333 - F1F0 ATP synthase subunit C 81333 - F1F0 ATP synthase subunit C | 0 | Direct |
57756,57756 57756 - Retrovirus zinc finger-like domains 57756 - Retrovirus zinc finger-like domains | 0 | Direct |
56601,48403 56601 - beta-lactamase/transpeptidase-like 48403 - Ankyrin repeat | 0 | Direct |
54665,56003 54665 - CO dehydrogenase molybdoprotein N-domain-like 56003 - Molybdenum cofactor-binding domain | 0 | Direct |
54897,52743 54897 - Protease propeptides/inhibitors 52743 - Subtilisin-like | 0 | Direct |
54849,52029 54849 - GroEL-intermediate domain like 52029 - GroEL apical domain-like | 0 | Direct |
53067,53067 53067 - Actin-like ATPase domain 53067 - Actin-like ATPase domain | 0 | Direct |
52283,51735 52283 - Formate/glycerate dehydrogenase catalytic domain-like 51735 - NAD(P)-binding Rossmann-fold domains | 0 | Direct |
100920,100934 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
161111,160240 161111 - Cation efflux protein transmembrane domain-like 160240 - Cation efflux protein cytoplasmic domain-like | 0 | Direct |
141673,50800 141673 - MOSC N-terminal domain-like 50800 - PK beta-barrel domain-like | 0 | Direct |
47220,47220 47220 - alpha-catenin/vinculin-like 47220 - alpha-catenin/vinculin-like | 0 | Direct |
50447,50465 50447 - Translation proteins 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
57938,49493 57938 - DnaJ/Hsp40 cysteine-rich domain 49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
54768,54768 54768 - dsRNA-binding domain-like 54768 - dsRNA-binding domain-like | 0 | Direct |
55681,52954 55681 - Class II aaRS and biotin synthetases 52954 - Class II aaRS ABD-related | 0 | Direct |
52540,140990 52540 - P-loop containing nucleoside triphosphate hydrolases 140990 - FtsH protease domain-like | 0 | Direct |
49348,55711 49348 - Clathrin adaptor appendage domain 55711 - Subdomain of clathrin and coatomer appendage domain | 0 | Direct |
54292,47741 54292 - 2Fe-2S ferredoxin-like 47741 - CO dehydrogenase ISP C-domain like | 0 | Direct |
57184,57184 57184 - Growth factor receptor domain 57184 - Growth factor receptor domain | 0 | Direct |
51556,51338 51556 - Metallo-dependent hydrolases 51338 - Composite domain of metallo-dependent hydrolases | 0 | Direct |
57889,57889 57889 - Cysteine-rich domain 57889 - Cysteine-rich domain | 0 | Direct |
50044,52540 50044 - SH3-domain 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
47090,55486 47090 - PGBD-like 55486 - Metalloproteases ("zincins"), catalytic domain | 0 | Direct |
57903,51197 57903 - FYVE/PHD zinc finger 51197 - Clavaminate synthase-like | 0 | Direct |
54585,52540 54585 - Cdc48 domain 2-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
81811,82754 81811 - Helical domain of Sec23/24 82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
55920,46785 55920 - Creatinase/aminopeptidase 46785 - "Winged helix" DNA-binding domain | 0 | Direct |
81324,81327 81324 - Voltage-gated potassium channels 81327 - Small-conductance potassium channel | 0 | Direct |
50978,50998 50978 - WD40 repeat-like 50998 - Quinoprotein alcohol dehydrogenase-like | 0 | Direct |
57850,117839 57850 - RING/U-box 117839 - WWE domain | 0 | Direct |
56672,100879 56672 - DNA/RNA polymerases 100879 - Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
55394,55394 55394 - Bactericidal permeability-increasing protein, BPI 55394 - Bactericidal permeability-increasing protein, BPI | 0 | Direct |
56059,51246 56059 - Glutathione synthetase ATP-binding domain-like 51246 - Rudiment single hybrid motif | 0 | Direct |
57625,57625 57625 - Invertebrate chitin-binding proteins 57625 - Invertebrate chitin-binding proteins | 0 | Direct |
90123,52540 90123 - ABC transporter transmembrane region 52540 - P-loop containing nucleoside triphosphate hydrolases | 0.01707 | Inherited |
52540,52540 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0.07493 | Inherited |
48452,48452 48452 - TPR-like 48452 - TPR-like | 0.09584 | Inherited |
56112,55073 56112 - Protein kinase-like (PK-like) 55073 - Nucleotide cyclase | 0.1201 | Inherited |
81660,56784 81660 - Metal cation-transporting ATPase, ATP-binding domain N 56784 - HAD-like | 0.1201 | Inherited |
56436,56436 56436 - C-type lectin-like 56436 - C-type lectin-like | 0.129 | Inherited |
52540,50447 52540 - P-loop containing nucleoside triphosphate hydrolases 50447 - Translation proteins | 0.1875 | Inherited |
56436,49854 56436 - C-type lectin-like 49854 - Spermadhesin, CUB domain | 0.2192 | Inherited |
51735,48179 51735 - NAD(P)-binding Rossmann-fold domains 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0.2334 | Inherited |
56784,81665 56784 - HAD-like 81665 - Calcium ATPase, transmembrane domain M | 0.2334 | Inherited |
52833,52833 52833 - Thioredoxin-like 52833 - Thioredoxin-like | 0.2902 | Inherited |
50978,50978 50978 - WD40 repeat-like 50978 - WD40 repeat-like | 0.2902 | Inherited |
47473,47473 47473 - EF-hand 47473 - EF-hand | 0.3231 | Inherited |
54928,54928 54928 - RNA-binding domain, RBD 54928 - RNA-binding domain, RBD | 0.3304 | Inherited |
63712,90112 63712 - Nicotinic receptor ligand binding domain-like 90112 - Neurotransmitter-gated ion-channel transmembrane pore | 0.3906 | Inherited |
57716,57716 57716 - Glucocorticoid receptor-like (DNA-binding domain) 57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0.4474 | Inherited |
52833,47616 52833 - Thioredoxin-like 47616 - GST C-terminal domain-like | 0.5016 | Inherited |
101690,53098 101690 - PAZ domain 53098 - Ribonuclease H-like | 0.5446 | Inherited |
90257,90257 90257 - Myosin rod fragments 90257 - Myosin rod fragments | 0.5446 | Inherited |
50044,55550 50044 - SH3-domain 55550 - SH2 domain | 0.5446 | Inherited |
51045,51045 51045 - WW domain 51045 - WW domain | 0.5996 | Inherited |
57903,57903 57903 - FYVE/PHD zinc finger 57903 - FYVE/PHD zinc finger | 0.6648 | Inherited |
50249,55681 50249 - Nucleic acid-binding proteins 55681 - Class II aaRS and biotin synthetases | 0.6648 | Inherited |
51905,54373 51905 - FAD/NAD(P)-binding domain 54373 - FAD-linked reductases, C-terminal domain | 0.667 | Inherited |
57196,57196 57196 - EGF/Laminin 57196 - EGF/Laminin | 0.6809 | Inherited |
55550,50044 55550 - SH2 domain 50044 - SH3-domain | 0.7358 | Inherited |
57716,48508 57716 - Glucocorticoid receptor-like (DNA-binding domain) 48508 - Nuclear receptor ligand-binding domain | 0.766 | Inherited |
48726,49265 48726 - Immunoglobulin 49265 - Fibronectin type III | 0.8028 | Inherited |
48726,48726 48726 - Immunoglobulin 48726 - Immunoglobulin | 0.8376 | Inherited |
54211,55666 54211 - Ribosomal protein S5 domain 2-like 55666 - Ribonuclease PH domain 2-like | 0.9179 | Inherited |
49562,49562 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0.9215 | Inherited |
52777,52777 52777 - CoA-dependent acyltransferases 52777 - CoA-dependent acyltransferases | 0.9472 | Inherited |
49785,49785 49785 - Galactose-binding domain-like 49785 - Galactose-binding domain-like | 0.9472 | Inherited |
57850,57845 57850 - RING/U-box 57845 - B-box zinc-binding domain | 1 | Inherited |
57850,57850 57850 - RING/U-box 57850 - RING/U-box | 1 | Inherited |
53300,56436 53300 - vWA-like 56436 - C-type lectin-like | 1 | Inherited |
(show details)
Supra-domains annotated to this WP term (Not in SPWP)
Highlighted in gray are those with FDR>0.001
Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
56645,47203,47203 56645 - Acyl-CoA dehydrogenase NM domain-like 47203 - Acyl-CoA dehydrogenase C-terminal domain-like 47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
46938,52087,101576 46938 - CRAL/TRIO N-terminal domain 52087 - CRAL/TRIO domain 101576 - Supernatant protein factor (SPF), C-terminal domain | 0 | DIRECT |
54292,47741,56176 54292 - 2Fe-2S ferredoxin-like 47741 - CO dehydrogenase ISP C-domain like 56176 - FAD-binding/transporter-associated domain-like | 0 | DIRECT |
57938,49493,49493 57938 - DnaJ/Hsp40 cysteine-rich domain 49493 - HSP40/DnaJ peptide-binding domain 49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
46966,46966,46966 46966 - Spectrin repeat 46966 - Spectrin repeat 46966 - Spectrin repeat | 0 | DIRECT |
50729,47473,51695 50729 - PH domain-like 47473 - EF-hand 51695 - PLC-like phosphodiesterases | 0 | DIRECT |
90123,52540,90123 90123 - ABC transporter transmembrane region 52540 - P-loop containing nucleoside triphosphate hydrolases 90123 - ABC transporter transmembrane region | 0 | DIRECT |
50249,50249,50249 50249 - Nucleic acid-binding proteins 50249 - Nucleic acid-binding proteins 50249 - Nucleic acid-binding proteins | 0 | DIRECT |
54928,54928,54928 54928 - RNA-binding domain, RBD 54928 - RNA-binding domain, RBD 54928 - RNA-binding domain, RBD | 0 | DIRECT |
81296,81296,81296 81296 - E set domains 81296 - E set domains 81296 - E set domains | 0 | DIRECT |
56436,49854,49854 56436 - C-type lectin-like 49854 - Spermadhesin, CUB domain 49854 - Spermadhesin, CUB domain | 0 | DIRECT |
50156,50044,52540 50156 - PDZ domain-like 50044 - SH3-domain 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
48371,48371,48371 48371 - ARM repeat 48371 - ARM repeat 48371 - ARM repeat | 0 | DIRECT |
54897,52743,49785 54897 - Protease propeptides/inhibitors 52743 - Subtilisin-like 49785 - Galactose-binding domain-like | 0 | DIRECT |
53738,53738,55957 53738 - Phosphoglucomutase, first 3 domains 53738 - Phosphoglucomutase, first 3 domains 55957 - Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
47090,55486,50923 47090 - PGBD-like 55486 - Metalloproteases ("zincins"), catalytic domain 50923 - Hemopexin-like domain | 0 | DIRECT |
54236,47031,50729 54236 - Ubiquitin-like 47031 - Second domain of FERM 50729 - PH domain-like | 0 | DIRECT |
49313,49313,49313 49313 - Cadherin-like 49313 - Cadherin-like 49313 - Cadherin-like | 0 | DIRECT |
55973,55973,55973 55973 - S-adenosylmethionine synthetase 55973 - S-adenosylmethionine synthetase 55973 - S-adenosylmethionine synthetase | 0 | DIRECT |
50044,55550,56112 50044 - SH3-domain 55550 - SH2 domain 56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
56968,48431,56968 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions 48431 - Lipovitellin-phosvitin complex, superhelical domain 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | DIRECT |
56112,82615,82615 56112 - Protein kinase-like (PK-like) 82615 - Polo-box domain 82615 - Polo-box domain | 0 | DIRECT |
54160,52540,52540 54160 - Chromo domain-like 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
53738,53738,53738 53738 - Phosphoglucomutase, first 3 domains 53738 - Phosphoglucomutase, first 3 domains 53738 - Phosphoglucomutase, first 3 domains | 0 | DIRECT |
48592,54849,52029 48592 - GroEL equatorial domain-like 54849 - GroEL-intermediate domain like 52029 - GroEL apical domain-like | 0 | DIRECT |
50692,54585,52540 50692 - ADC-like 54585 - Cdc48 domain 2-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
57362,57362,57362 57362 - BPTI-like 57362 - BPTI-like 57362 - BPTI-like | 0 | DIRECT |
82895,82895,82895 82895 - TSP-1 type 1 repeat 82895 - TSP-1 type 1 repeat 82895 - TSP-1 type 1 repeat | 0 | DIRECT |
57414,57414,57414 57414 - Hairpin loop containing domain-like 57414 - Hairpin loop containing domain-like 57414 - Hairpin loop containing domain-like | 0 | DIRECT |
52540,90123,52540 52540 - P-loop containing nucleoside triphosphate hydrolases 90123 - ABC transporter transmembrane region 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
57625,57625,57625 57625 - Invertebrate chitin-binding proteins 57625 - Invertebrate chitin-binding proteins 57625 - Invertebrate chitin-binding proteins | 0 | DIRECT |
52440,56059,51246 52440 - PreATP-grasp domain 56059 - Glutathione synthetase ATP-binding domain-like 51246 - Rudiment single hybrid motif | 0 | DIRECT |
52540,50447,50465 52540 - P-loop containing nucleoside triphosphate hydrolases 50447 - Translation proteins 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
49899,49899,49899 49899 - Concanavalin A-like lectins/glucanases 49899 - Concanavalin A-like lectins/glucanases 49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
57535,57535,57535 57535 - Complement control module/SCR domain 57535 - Complement control module/SCR domain 57535 - Complement control module/SCR domain | 0 | DIRECT |
50044,50044,50044 50044 - SH3-domain 50044 - SH3-domain 50044 - SH3-domain | 0 | DIRECT |
57567,57567,57567 57567 - Serine protease inhibitors 57567 - Serine protease inhibitors 57567 - Serine protease inhibitors | 0 | DIRECT |
54585,52540,52540 54585 - Cdc48 domain 2-like 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
74788,75632,46785 74788 - Cullin repeat-like 75632 - Cullin homology domain 46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
51735,48179,48179 51735 - NAD(P)-binding Rossmann-fold domains 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | DIRECT |
52540,52540,52540 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
74650,51445,51011 74650 - Galactose mutarotase-like 51445 - (Trans)glycosidases 51011 - Glycosyl hydrolase domain | 0 | DIRECT |
48452,48452,48452 48452 - TPR-like 48452 - TPR-like 48452 - TPR-like | 0 | DIRECT |
53067,53067,100920 53067 - Actin-like ATPase domain 53067 - Actin-like ATPase domain 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
54160,54160,52540 54160 - Chromo domain-like 54160 - Chromo domain-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
48726,49265,48726 48726 - Immunoglobulin 49265 - Fibronectin type III 48726 - Immunoglobulin | 0 | DIRECT |
49562,48371,56112 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) 48371 - ARM repeat 56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
53067,100920,100934 53067 - Actin-like ATPase domain 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
81660,56784,81665 81660 - Metal cation-transporting ATPase, ATP-binding domain N 56784 - HAD-like 81665 - Calcium ATPase, transmembrane domain M | 0.1342 | INHERITED FROM: nicotine hypersensitive || lipid composition variant |
56436,56436,49854 56436 - C-type lectin-like 56436 - C-type lectin-like 49854 - Spermadhesin, CUB domain | 0.3578 | INHERITED FROM: cadmium response variant || cadmium hypersensitive |
57424,57424,57424 57424 - LDL receptor-like module 57424 - LDL receptor-like module 57424 - LDL receptor-like module | 0.3598 | INHERITED FROM: protein expression reduced |
52833,52833,52833 52833 - Thioredoxin-like 52833 - Thioredoxin-like 52833 - Thioredoxin-like | 0.3598 | INHERITED FROM: protein interaction variant || protein aggregation variant || protein protein interaction variant || pattern of transgene expression variant |
57716,57716,57716 57716 - Glucocorticoid receptor-like (DNA-binding domain) 57716 - Glucocorticoid receptor-like (DNA-binding domain) 57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0.4431 | INHERITED FROM: protein expression variant || level of protein expression variant || protein expression reduced || organism metabolism processing variant || protein degradation variant |
57850,57850,57850 57850 - RING/U-box 57850 - RING/U-box 57850 - RING/U-box | 0.8368 | INHERITED FROM: protein interaction variant || protein aggregation variant || transgene subcellular localization variant || protein protein interaction variant || pattern of transgene expression variant |
48726,48726,48726 48726 - Immunoglobulin 48726 - Immunoglobulin 48726 - Immunoglobulin | 0.9441 | INHERITED FROM: growth rate variant || protein degradation variant |
48726,48726,49265 48726 - Immunoglobulin 48726 - Immunoglobulin 49265 - Fibronectin type III | 0.9906 | INHERITED FROM: growth rate variant || protein degradation variant |
Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
56645,47203,47203 56645 - Acyl-CoA dehydrogenase NM domain-like 47203 - Acyl-CoA dehydrogenase C-terminal domain-like 47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
46938,52087,101576 46938 - CRAL/TRIO N-terminal domain 52087 - CRAL/TRIO domain 101576 - Supernatant protein factor (SPF), C-terminal domain | 0 | Direct |
54292,47741,56176 54292 - 2Fe-2S ferredoxin-like 47741 - CO dehydrogenase ISP C-domain like 56176 - FAD-binding/transporter-associated domain-like | 0 | Direct |
57938,49493,49493 57938 - DnaJ/Hsp40 cysteine-rich domain 49493 - HSP40/DnaJ peptide-binding domain 49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
46966,46966,46966 46966 - Spectrin repeat 46966 - Spectrin repeat 46966 - Spectrin repeat | 0 | Direct |
50729,47473,51695 50729 - PH domain-like 47473 - EF-hand 51695 - PLC-like phosphodiesterases | 0 | Direct |
90123,52540,90123 90123 - ABC transporter transmembrane region 52540 - P-loop containing nucleoside triphosphate hydrolases 90123 - ABC transporter transmembrane region | 0 | Direct |
50249,50249,50249 50249 - Nucleic acid-binding proteins 50249 - Nucleic acid-binding proteins 50249 - Nucleic acid-binding proteins | 0 | Direct |
54928,54928,54928 54928 - RNA-binding domain, RBD 54928 - RNA-binding domain, RBD 54928 - RNA-binding domain, RBD | 0 | Direct |
81296,81296,81296 81296 - E set domains 81296 - E set domains 81296 - E set domains | 0 | Direct |
56436,49854,49854 56436 - C-type lectin-like 49854 - Spermadhesin, CUB domain 49854 - Spermadhesin, CUB domain | 0 | Direct |
50156,50044,52540 50156 - PDZ domain-like 50044 - SH3-domain 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
48371,48371,48371 48371 - ARM repeat 48371 - ARM repeat 48371 - ARM repeat | 0 | Direct |
54897,52743,49785 54897 - Protease propeptides/inhibitors 52743 - Subtilisin-like 49785 - Galactose-binding domain-like | 0 | Direct |
53738,53738,55957 53738 - Phosphoglucomutase, first 3 domains 53738 - Phosphoglucomutase, first 3 domains 55957 - Phosphoglucomutase, C-terminal domain | 0 | Direct |
47090,55486,50923 47090 - PGBD-like 55486 - Metalloproteases ("zincins"), catalytic domain 50923 - Hemopexin-like domain | 0 | Direct |
54236,47031,50729 54236 - Ubiquitin-like 47031 - Second domain of FERM 50729 - PH domain-like | 0 | Direct |
49313,49313,49313 49313 - Cadherin-like 49313 - Cadherin-like 49313 - Cadherin-like | 0 | Direct |
55973,55973,55973 55973 - S-adenosylmethionine synthetase 55973 - S-adenosylmethionine synthetase 55973 - S-adenosylmethionine synthetase | 0 | Direct |
50044,55550,56112 50044 - SH3-domain 55550 - SH2 domain 56112 - Protein kinase-like (PK-like) | 0 | Direct |
56968,48431,56968 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions 48431 - Lipovitellin-phosvitin complex, superhelical domain 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | Direct |
56112,82615,82615 56112 - Protein kinase-like (PK-like) 82615 - Polo-box domain 82615 - Polo-box domain | 0 | Direct |
54160,52540,52540 54160 - Chromo domain-like 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
53738,53738,53738 53738 - Phosphoglucomutase, first 3 domains 53738 - Phosphoglucomutase, first 3 domains 53738 - Phosphoglucomutase, first 3 domains | 0 | Direct |
48592,54849,52029 48592 - GroEL equatorial domain-like 54849 - GroEL-intermediate domain like 52029 - GroEL apical domain-like | 0 | Direct |
50692,54585,52540 50692 - ADC-like 54585 - Cdc48 domain 2-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
57362,57362,57362 57362 - BPTI-like 57362 - BPTI-like 57362 - BPTI-like | 0 | Direct |
82895,82895,82895 82895 - TSP-1 type 1 repeat 82895 - TSP-1 type 1 repeat 82895 - TSP-1 type 1 repeat | 0 | Direct |
57414,57414,57414 57414 - Hairpin loop containing domain-like 57414 - Hairpin loop containing domain-like 57414 - Hairpin loop containing domain-like | 0 | Direct |
52540,90123,52540 52540 - P-loop containing nucleoside triphosphate hydrolases 90123 - ABC transporter transmembrane region 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
57625,57625,57625 57625 - Invertebrate chitin-binding proteins 57625 - Invertebrate chitin-binding proteins 57625 - Invertebrate chitin-binding proteins | 0 | Direct |
52440,56059,51246 52440 - PreATP-grasp domain 56059 - Glutathione synthetase ATP-binding domain-like 51246 - Rudiment single hybrid motif | 0 | Direct |
52540,50447,50465 52540 - P-loop containing nucleoside triphosphate hydrolases 50447 - Translation proteins 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
49899,49899,49899 49899 - Concanavalin A-like lectins/glucanases 49899 - Concanavalin A-like lectins/glucanases 49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
57535,57535,57535 57535 - Complement control module/SCR domain 57535 - Complement control module/SCR domain 57535 - Complement control module/SCR domain | 0 | Direct |
50044,50044,50044 50044 - SH3-domain 50044 - SH3-domain 50044 - SH3-domain | 0 | Direct |
57567,57567,57567 57567 - Serine protease inhibitors 57567 - Serine protease inhibitors 57567 - Serine protease inhibitors | 0 | Direct |
54585,52540,52540 54585 - Cdc48 domain 2-like 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
74788,75632,46785 74788 - Cullin repeat-like 75632 - Cullin homology domain 46785 - "Winged helix" DNA-binding domain | 0 | Direct |
51735,48179,48179 51735 - NAD(P)-binding Rossmann-fold domains 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | Direct |
52540,52540,52540 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
74650,51445,51011 74650 - Galactose mutarotase-like 51445 - (Trans)glycosidases 51011 - Glycosyl hydrolase domain | 0 | Direct |
48452,48452,48452 48452 - TPR-like 48452 - TPR-like 48452 - TPR-like | 0 | Direct |
53067,53067,100920 53067 - Actin-like ATPase domain 53067 - Actin-like ATPase domain 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
54160,54160,52540 54160 - Chromo domain-like 54160 - Chromo domain-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
48726,49265,48726 48726 - Immunoglobulin 49265 - Fibronectin type III 48726 - Immunoglobulin | 0 | Direct |
49562,48371,56112 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) 48371 - ARM repeat 56112 - Protein kinase-like (PK-like) | 0 | Direct |
53067,100920,100934 53067 - Actin-like ATPase domain 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
81660,56784,81665 81660 - Metal cation-transporting ATPase, ATP-binding domain N 56784 - HAD-like 81665 - Calcium ATPase, transmembrane domain M | 0.1342 | Inherited |
56436,56436,49854 56436 - C-type lectin-like 56436 - C-type lectin-like 49854 - Spermadhesin, CUB domain | 0.3578 | Inherited |
57424,57424,57424 57424 - LDL receptor-like module 57424 - LDL receptor-like module 57424 - LDL receptor-like module | 0.3598 | Inherited |
52833,52833,52833 52833 - Thioredoxin-like 52833 - Thioredoxin-like 52833 - Thioredoxin-like | 0.3598 | Inherited |
57716,57716,57716 57716 - Glucocorticoid receptor-like (DNA-binding domain) 57716 - Glucocorticoid receptor-like (DNA-binding domain) 57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0.4431 | Inherited |
57850,57850,57850 57850 - RING/U-box 57850 - RING/U-box 57850 - RING/U-box | 0.8368 | Inherited |
48726,48726,48726 48726 - Immunoglobulin 48726 - Immunoglobulin 48726 - Immunoglobulin | 0.9441 | Inherited |
48726,48726,49265 48726 - Immunoglobulin 48726 - Immunoglobulin 49265 - Fibronectin type III | 0.9906 | Inherited |
Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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