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Worm Phenotype (WP): organism homeostasis metabolism variant

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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)

Shortest distance to current term (+ for parents, - for children) WP term [WP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   Variant [WBPhenotype:0000886] <2>
+ + 2:   physiology variant [WBPhenotype:0000519] <14>(510|587) (510|248|68)
+ 1:   organism physiology variant [WBPhenotype:0000576] <9>(369|431) (372|193|56)
0:   organism homeostasis metabolism variant [WBPhenotype:0000577] <16>(361|421) (363|190|55)
- 1:   organism metabolism processing variant [WBPhenotype:0000027] <25>(178|190) (182|87|26)
- 1:   organism environmental stimulus response variant [WBPhenotype:0000738] <15>(138|128) (139|57|18)
- 1:   RNAi response variant [WBPhenotype:0000743] <11>(8|10) (8|5|2)
- 1:   metal homeostasis variant [WBPhenotype:0002029] <6>(0|0) (0|0|0)
- 1:   growth variant [WBPhenotype:0000030] <5>(202|266) (204|116|38)
- 1:   maintenance of gene silencing variant [WBPhenotype:0002063] <4>(11|8) (11|2|0)
- 1:   hydrogen peroxide homeostasis variant [WBPhenotype:0002003] <2>(1|1) (1|0|0)
- 1:   osmotic integrity variant [WBPhenotype:0000041] <2>(6|7) (6|1|0)
- 1:   reactive oxygen species homeostasis variant [WBPhenotype:0002182] <2>(1|1) (1|0|0)
- 1:   spontaneous mutation rate increased [WBPhenotype:0000228] <2>(6|5) (6|3|1)
- 1:   ascaroside biosynthesis variant [WBPhenotype:0002051] <1>(2|2) (2|2|1)
- 1:   cation homeostasis variant [WBPhenotype:0002073](0|0) (0|0|0)
- 1:   hypersensitive to laser ablation [WBPhenotype:0001998](0|0) (0|0|0)
- 1:   hypersensitivity to mutagen [WBPhenotype:0001781](0|0) (0|0|0)
- 1:   protein signaling variant [WBPhenotype:0001207](0|0) (0|0|0)
- 1:   starved [WBPhenotype:0000547](0|0) (0|0|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Integrin alpha N-terminal domain0Direct
Cytochrome c0Direct
Class II aaRS ABD-related0Direct
FAD-linked oxidases, C-terminal domain0Direct
JAB1/MPN domain0Direct
BEACH domain0Direct
Ferritin-like0Direct
ACP-like0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
VPS9 domain0Direct
MFPT repeat-like0Direct
PEP carboxykinase-like0Direct
ADP-ribosylation0Direct
Families 57/38 glycoside transferase middle domain0Direct
Thyroglobulin type-1 domain0Direct
HSP40/DnaJ peptide-binding domain0Direct
Intermediate filament protein, coiled coil region0Direct
GroEL apical domain-like0Direct
t-snare proteins0Direct
Lipovitellin-phosvitin complex, superhelical domain0Direct
Glycolipid transfer protein, GLTP0Direct
F1F0 ATP synthase subunit C0Direct
Zn-finger domain of Sec23/240Direct
Translational machinery components0Direct
alpha-catenin/vinculin-like0Direct
TGS-like0Direct
FAD/NAD-linked reductases, dimerisation (C-terminal) domain0Direct
Tubulin nucleotide-binding domain-like0Direct
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0Direct
Nucleoporin domain0Direct
PEBP-like0Direct
L30e-like0Direct
Sec1/munc18-like (SM) proteins0Direct
CO dehydrogenase molybdoprotein N-domain-like0Direct
ARID-like0Direct
ValRS/IleRS/LeuRS editing domain0Direct
Subdomain of clathrin and coatomer appendage domain0Direct
Tim10-like0Direct
Heat shock protein 70kD (HSP70), C-terminal subdomain0Direct
Proton glutamate symport protein0Direct
ArfGap/RecO-like zinc finger0Direct
Band 7/SPFH domain0Direct
Polo-box domain0Direct
FAD-dependent thiol oxidase0Direct
FAD-binding/transporter-associated domain-like0Direct
Succinyl-CoA synthetase domains0Direct
Carboxypeptidase regulatory domain-like0Direct
PurM C-terminal domain-like0Direct
LDH C-terminal domain-like0Direct
Composite domain of metallo-dependent hydrolases0Direct
Spectrin repeat0Direct
Class I glutamine amidotransferase-like0Direct
Lesion bypass DNA polymerase (Y-family), little finger domain0Direct
CO dehydrogenase ISP C-domain like0Direct
PABC (PABP) domain0Direct
DNA ligase/mRNA capping enzyme, catalytic domain0Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0Direct
LysM domain0Direct
Transducin (alpha subunit), insertion domain0Direct
Molybdenum cofactor-binding domain0Direct
Cadherin-like0Direct
Skp1 dimerisation domain-like0Direct
Troponin coil-coiled subunits0Direct
3-carboxy-cis,cis-mucoante lactonizing enzyme0Direct
Acid phosphatase/Vanadium-dependent haloperoxidase0Direct
LEM domain0Direct
Profilin (actin-binding protein)0Direct
Tryptophan synthase beta subunit-like PLP-dependent enzymes0Direct
Chitinase insertion domain0Direct
Small-conductance potassium channel0Direct
Formate/glycerate dehydrogenase catalytic domain-like0Direct
Galactose mutarotase-like0Direct
Outer arm dynein light chain 10Direct
Tubulin C-terminal domain-like0Direct
HCP-like0Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase0Direct
R3H domain0Direct
Subtilisin-like0Direct
beta-lactamase/transpeptidase-like0Direct
cAMP-binding domain-like0Direct
Cullin homology domain0Direct
FF domain0Direct
Thiamin diphosphate-binding fold (THDP-binding)0Direct
Thiolase-like0Direct
CBD9-like0Direct
Phosphoenolpyruvate/pyruvate domain0Direct
Heme-dependent catalase-like0Direct
HRDC-like0Direct
Cation efflux protein cytoplasmic domain-like0Direct
2Fe-2S ferredoxin-like0Direct
Tubby C-terminal domain-like0Direct
Surp module (SWAP domain)0Direct
Citrate synthase0Direct
5' to 3' exonuclease, C-terminal subdomain0Direct
PK beta-barrel domain-like0Direct
SIS domain0Direct
Aquaporin-like0Direct
YbiA-like0Direct
Protease propeptides/inhibitors0Direct
PGBD-like0Direct
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0Direct
PAP/OAS1 substrate-binding domain0Direct
lambda repressor-like DNA-binding domains0Direct
GAS2 domain-like0Direct
Cu,Zn superoxide dismutase-like0Direct
Acetyl-CoA synthetase-like0Direct
Invertebrate chitin-binding proteins0Direct
Rap/Ran-GAP0Direct
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit0Direct
YWTD domain0Direct
RBP11-like subunits of RNA polymerase0Direct
Smc hinge domain0Direct
MOSC N-terminal domain-like0Direct
Glutathione synthetase ATP-binding domain-like0Direct
Ribosomal L27 protein-like0Direct
Zn-binding ribosomal proteins0Direct
Clathrin adaptor appendage domain0Direct
SMAD MH1 domain0Direct
Lamin A/C globular tail domain0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Sec7 domain0Direct
Ribosomal proteins S24e, L23 and L15e0Direct
CAD & PB1 domains0Direct
AN1-like Zinc finger0Direct
HSP90 C-terminal domain0Direct
Doublecortin (DC)0Direct
Ribosomal protein L10Direct
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase0Direct
SAICAR synthase-like0Direct
Terpenoid cyclases/Protein prenyltransferases0Direct
Ribosomal protein S100Direct
GroEL equatorial domain-like0Direct
PurM N-terminal domain-like0Direct
Activating enzymes of the ubiquitin-like proteins0Direct
WGR domain-like0Direct
Ribosomal protein S180Direct
L-aspartase-like0Direct
Annexin0Direct
Phoshotransferase/anion transport protein0Direct
Galactose oxidase, central domain0Direct
alpha/beta knot0Direct
MgtE membrane domain-like0Direct
PIN domain-like0Direct
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain0Direct
Retrovirus zinc finger-like domains0Direct
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain0Direct
Elafin-like0Direct
Heat shock protein 70kD (HSP70), peptide-binding domain0Direct
Domain of poly(ADP-ribose) polymerase0Direct
Integrin domains0Direct
Epsilon subunit of mitochondrial F1F0-ATP synthase0Direct
ISP domain0Direct
Nucleoside diphosphate kinase, NDK0Direct
Chromo domain-like0Direct
NagB/RpiA/CoA transferase-like0Direct
S-adenosylmethionine synthetase0Direct
Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase)0Direct
Radical SAM enzymes0Direct
Molybdenum cofactor biosynthesis proteins0Direct
TK C-terminal domain-like0Direct
Mitochondrial carrier0Direct
Cystatin/monellin0Direct
Fibrinogen C-terminal domain-like0Direct
Creatinase/prolidase N-terminal domain0Direct
Terpenoid synthases0Direct
CRAL/TRIO N-terminal domain0Direct
GAT-like domain0Direct
Cdc48 domain 2-like0Direct
GYF domain0Direct
Blood coagulation inhibitor (disintegrin)0Direct
14-3-3 protein0Direct
Transducin (heterotrimeric G protein), gamma chain0Direct
Cullin repeat-like0Direct
Oxysterol-binding protein-like0Direct
Nop domain0Direct
PLC-like phosphodiesterases0Direct
Hormone receptor domain0Direct
Sec63 N-terminal domain-like0Direct
Histone-fold0Direct
eIF4e-like0Direct
SAND domain-like0Direct
Phosphoglucomutase, first 3 domains0Direct
Hedgehog/intein (Hint) domain0Direct
MIR domain0Direct
DNA repair protein MutS, domain III0Direct
SPOC domain-like0Direct
Putative DNA-binding domain0Direct
PEP carboxykinase N-terminal domain0Direct
Complement control module/SCR domain0Direct
PHM/PNGase F0Direct
Pepsin inhibitor-30Direct
Actin-like ATPase domain0Direct
C-terminal, gelsolin-like domain of Sec23/240Direct
Rudiment single hybrid motif0Direct
WWE domain0Direct
Single hybrid motif0Direct
GroEL-intermediate domain like0Direct
Carbohydrate phosphatase0Direct
Aldolase0Direct
Lipovitellin-phosvitin complex; beta-sheet shell regions0Direct
PAP/Archaeal CCA-adding enzyme, C-terminal domain0Direct
Ribokinase-like0Direct
DnaJ/Hsp40 cysteine-rich domain0Direct
Pentein0Direct
ThrRS/AlaRS common domain0Direct
Ribulose-phoshate binding barrel0Direct
Clc chloride channel0Direct
Aminoacid dehydrogenase-like, N-terminal domain0Direct
DEATH domain0Direct
GroES-like0Direct
Periplasmic binding protein-like II0Direct
Arginase/deacetylase0Direct
Restriction endonuclease-like0Direct
Heme-dependent peroxidases0Direct
Carbon-nitrogen hydrolase0Direct
SWIB/MDM2 domain0Direct
Second domain of FERM0Direct
Helical domain of Sec23/240Direct
Isocitrate/Isopropylmalate dehydrogenase-like0Direct
PLP-binding barrel0Direct
PreATP-grasp domain0Direct
ENTH/VHS domain0Direct
Chaperone J-domain0Direct
Diaminopimelate epimerase-like0Direct
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0Direct
Ran binding protein zinc finger-like0Direct
Ribosomal protein L10-like0Direct
Hypothetical protein c14orf129, hspc2100Direct
Bacterial exopeptidase dimerisation domain0Direct
PYP-like sensor domain (PAS domain)0Direct
Aromatic aminoacid monoxygenases, catalytic and oligomerization domains0Direct
Nucleotidyltransferase0Direct
Phosphoglucomutase, C-terminal domain0Direct
HSP20-like chaperones0Direct
ALDH-like0Direct
FtsH protease domain-like0Direct
Tricorn protease domain 20Direct
PH domain-like0.00001282Direct
PDZ domain-like0.007203Inherited
TPR-like0.009752Inherited
ARM repeat0.01392Inherited
ABC transporter transmembrane region0.01722Inherited
SH3-domain0.03991Inherited
Homeodomain-like0.04118Inherited
WD40 repeat-like0.04816Inherited
CCCH zinc finger0.06231Inherited
Translation proteins0.07835Inherited
"Winged helix" DNA-binding domain0.07882Inherited
HLH, helix-loop-helix DNA-binding domain0.08967Inherited
SMAD/FHA domain0.09815Inherited
Calcium ATPase, transmembrane domain M0.11Inherited
EGF/Laminin0.1181Inherited
Regulator of G-protein signaling, RGS0.1233Inherited
Metal cation-transporting ATPase, ATP-binding domain N0.1233Inherited
Acid proteases0.138Inherited
Calcium ATPase, transduction domain A0.138Inherited
Cysteine-rich domain0.1423Inherited
Quinoprotein alcohol dehydrogenase-like0.1541Inherited
Multidrug efflux transporter AcrB transmembrane domain0.1557Inherited
Cytochrome P4500.16Inherited
(Trans)glycosidases0.1699Inherited
P-loop containing nucleoside triphosphate hydrolases0.1716Inherited
HMG-box0.1722Inherited
DBL homology domain (DH-domain)0.1722Inherited
ClpP/crotonase0.1722Inherited
Ankyrin repeat0.1826Inherited
Cysteine proteinases0.2142Inherited
POZ domain0.22Inherited
Cyclin-like0.2211Inherited
6-phosphogluconate dehydrogenase C-terminal domain-like0.2397Inherited
Bromodomain0.2397Inherited
Tudor/PWWP/MBT0.2397Inherited
Metallo-dependent phosphatases0.2531Inherited
RNA-binding domain, RBD0.2567Inherited
Lipocalins0.261Inherited
SNARE-like0.2667Inherited
Cation efflux protein transmembrane domain-like0.3312Inherited
PX domain0.3312Inherited
Nicotinic receptor ligand binding domain-like0.3365Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.3762Inherited
RNI-like0.392Inherited
HD-domain/PDEase-like0.4076Inherited
FKBP-like0.4076Inherited
Class II aaRS and biotin synthetases0.4184Inherited
Hect, E3 ligase catalytic domain0.4519Inherited
DHS-like NAD/FAD-binding domain0.4519Inherited
Myosin rod fragments0.4519Inherited
PRTase-like0.4519Inherited
Galactose-binding domain-like0.4721Inherited
SH2 domain0.4733Inherited
Sm-like ribonucleoproteins0.484Inherited
Cystine-knot cytokines0.484Inherited
Voltage-gated potassium channels0.4979Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.5007Inherited
Calpain large subunit, middle domain (domain III)0.5007Inherited
Riboflavin synthase domain-like0.5007Inherited
WW domain0.5183Inherited
UBC-like0.5201Inherited
SAM/Pointed domain0.5213Inherited
Protein kinase-like (PK-like)0.5257Inherited
Seven-hairpin glycosidases0.5556Inherited
Multidrug resistance efflux transporter EmrE0.557Inherited
C2 domain (Calcium/lipid-binding domain, CaLB)0.577Inherited
S-adenosyl-L-methionine-dependent methyltransferases0.608Inherited
Di-copper centre-containing domain0.6117Inherited
KA1-like0.6117Inherited
HIT/MYND zinc finger-like0.6321Inherited
GST C-terminal domain-like0.6586Inherited
Frizzled cysteine-rich domain0.6771Inherited
S15/NS1 RNA-binding domain0.6771Inherited
4Fe-4S ferredoxins0.6771Inherited
alpha/beta-Hydrolases0.6971Inherited
MIT domain0.7478Inherited
ADC-like0.7478Inherited
Clavaminate synthase-like0.7901Inherited
NAD kinase/diacylglycerol kinase-like0.8023Inherited
Cyclophilin-like0.8082Inherited
CoA-dependent acyltransferases0.8082Inherited
EF-hand0.8236Inherited
SNF-like0.8388Inherited
Leucine zipper domain0.8422Inherited
GTPase activation domain, GAP0.8485Inherited
Eukaryotic type KH-domain (KH-domain type I)0.8485Inherited
Ubiquitin-like0.8489Inherited
Thioredoxin-like0.8606Inherited
Ribonuclease H-like0.8829Inherited
Immunoglobulin0.8882Inherited
p53-like transcription factors0.8914Inherited
Nucleic acid-binding proteins0.8959Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.9018Inherited
MFS general substrate transporter0.9102Inherited
FYVE/PHD zinc finger0.9153Inherited
Nucleotide-diphospho-sugar transferases0.9173Inherited
HAD-like0.924Inherited
Ribonuclease PH domain 2-like0.9265Inherited
Saposin0.9479Inherited
FAD/NAD(P)-binding domain0.9495Inherited
Periplasmic binding protein-like I0.9495Inherited
PLP-dependent transferases0.9559Inherited
Nucleotide cyclase0.9619Inherited
Ribosomal protein S5 domain 2-like0.9704Inherited
SET domain0.9772Inherited
PAZ domain0.9837Inherited
Ligand-binding domain in the NO signalling and Golgi transport0.9971Inherited
beta-beta-alpha zinc fingers1Inherited
dsRNA-binding domain-like1Inherited
Nuclear receptor ligand-binding domain1Inherited
PapD-like1Inherited
F-box domain1Inherited
Acyl-CoA dehydrogenase NM domain-like1Inherited
Translation proteins SH3-like domain1Inherited
B-box zinc-binding domain1Inherited
Acyl-CoA dehydrogenase C-terminal domain-like1Inherited
Bet v1-like1Inherited
UBA-like1Inherited
Snake toxin-like1Inherited
Family A G protein-coupled receptor-like1Inherited
Nucleotidylyl transferase1Inherited
RING/U-box1Inherited
DNA/RNA polymerases1Inherited
Insulin-like1Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
HSP90 C-terminal domain0Direct
NOL1/NOP2/sun0Direct
WWE domain0Direct
LEM domain0Direct
Sir2 family of transcriptional regulators0Direct
5' to 3' exonuclease catalytic domain0Direct
PurM N-terminal domain-like0Direct
Cullin repeat0Direct
RecA protein-like (ATPase-domain)0Direct
Glycogenin0Direct
Sec63 C-terminal domain-like0Direct
Adenosine/AMP deaminase0Direct
CoA-binding domain0Direct
Class II glutamine amidotransferases0Direct
Ribosomal protein S100Direct
Skp1 dimerisation domain-like0Direct
Second domain of FERM0Direct
SWIB/MDM2 domain0Direct
Translational machinery components0Direct
Clathrin adaptor core protein0Direct
Acylamino-acid-releasing enzyme, C-terminal donain0Direct
ALDH-like0Direct
Sec7 domain0Direct
DPP6 catalytic domain-like0Direct
Aminoacid dehydrogenase-like, C-terminal domain0Direct
Pancreatic carboxypeptidases0Direct
PDI-like0Direct
Tim10/DDP0Direct
Fatty acid binding protein-like0Direct
Pepsin inhibitor-30Direct
DnaJ/Hsp40 cysteine-rich domain0Direct
Actin/HSP700Direct
Transducin (heterotrimeric G protein), gamma chain0Direct
BEACH domain0Direct
L-aminoacid/polyamine oxidase0Direct
Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase)0Direct
Epsilon subunit of mitochondrial F1F0-ATP synthase0Direct
a tRNA synthase domain0Direct
RNA-polymerase beta-prime0Direct
Mitochondrial carrier0Direct
AMPK-beta glycogen binding domain-like0Direct
Intermediate filament protein, coiled coil region0Direct
Arylsulfatase0Direct
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0Direct
D-aminoacid oxidase, N-terminal domain0Direct
Formate/glycerate dehydrogenases, NAD-domain0Direct
Cu,Zn superoxide dismutase-like0Direct
DPP6 N-terminal domain-like0Direct
Regulator of G-protein signaling, RGS0Direct
Band 7/SPFH domain0Direct
14-3-3 protein0Direct
Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain0Direct
Acireductone dioxygenase0Direct
Branched-chain alpha-keto acid dehydrogenase PP module0Direct
HCDH C-domain-like0Direct
XPF/Rad1/Mus81 nuclease0Direct
CO dehydrogenase ISP C-domain like0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
COMT-like0Direct
Ribokinase-like0Direct
Gamma-glutamyltranspeptidase-like0Direct
F1F0 ATP synthase subunit C0Direct
Ribosomal protein L18 and S110Direct
HEAT repeat0Direct
La domain0Direct
Heat shock protein 70kD (HSP70), C-terminal subdomain0Direct
Dimeric isocitrate & isopropylmalate dehydrogenases0Direct
1,3-glucuronyltransferase0Direct
GYF domain0Direct
beta 1,4 galactosyltransferase (b4GalT1)0Direct
VHS domain0Direct
Small-conductance potassium channel0Direct
PhzC/PhzF-like0Direct
ValRS/IleRS/LeuRS editing domain0Direct
Cadherin0Direct
Elafin-like0Direct
Vertebrate phospholipase A20Direct
Ran binding protein zinc finger-like0Direct
Calcium ATPase, transmembrane domain M0Direct
Anticodon-binding domain of Class II aaRS0Direct
Protein prenyltransferases0Direct
PaaI/YdiI-like0Direct
Alcohol dehydrogenase-like, C-terminal domain0Direct
CO dehydrogenase molybdoprotein N-domain-like0Direct
Hedgehog C-terminal (Hog) autoprocessing domain0Direct
CoA transferase alpha subunit-like0Direct
28-residue LRR0Direct
Lamin A/C globular tail domain0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Clathrin coat assembly domain0Direct
Ubiquitin activating enzymes (UBA)0Direct
MOSC N-terminal domain-like0Direct
Proton glutamate symport protein0Direct
Tubulin, C-terminal domain0Direct
FtsH protease domain-like0Direct
SAM (sterile alpha motif) domain0Direct
Arginine methyltransferase0Direct
RNA editing terminal uridyl transferase 2, RET2, domain 20Direct
beta-Lactamase/D-ala carboxypeptidase0Direct
Profilin (actin-binding protein)0Direct
Fibrinogen C-terminal domain-like0Direct
Group II chaperonin (CCT, TRIC), apical domain0Direct
MIR domain0Direct
Glycerol kinase0Direct
YicI catalytic domain-like0Direct
Carboxypeptidase regulatory domain0Direct
Surp module (SWAP domain)0Direct
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0Direct
LysM domain0Direct
PEP carboxykinase N-terminal domain0Direct
FAD/NAD-linked reductases, dimerisation (C-terminal) domain0Direct
Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain0Direct
FHA domain0Direct
Armadillo repeat0Direct
acyl-CoA oxidase C-terminal domains0Direct
Inositol polyphosphate 5-phosphatase (IPP5)0Direct
Molybdenum cofactor-binding domain0Direct
SMAD MH1 domain0Direct
Phoshoinositide 3-kinase (PI3K), catalytic domain0Direct
Blood coagulation inhibitor (disintegrin)0Direct
Amylase, catalytic domain0Direct
Mammalian PLC0Direct
TBP-associated factors, TAFs0Direct
Phosphatidylethanolamine binding protein0Direct
alpha-mannosidase0Direct
Internalin LRR domain0Direct
Ubiquitin carboxyl-terminal hydrolase UCH-L0Direct
Serum paraoxonase/arylesterase 1, PON10Direct
BC C-terminal domain-like0Direct
FF domain0Direct
Lipovitellin-phosvitin complex, superhelical domain0Direct
Ribosomal protein L10Direct
Nucleosome core histones0Direct
Poly(A) polymerase, PAP, N-terminal domain0Direct
Class I glutamine amidotransferases (GAT)0Direct
Chitinase insertion domain0Direct
Class I aldolase0Direct
YihX-like0Direct
Poly(A) polymerase, PAP, middle domain0Direct
Ngr ectodomain-like0Direct
HSP40/DnaJ peptide-binding domain0Direct
Complement control module/SCR domain0Direct
beta-sandwich domain of Sec23/240Direct
Phosphate binding protein-like0Direct
Chromo domain0Direct
Clc chloride channel0Direct
Reductases0Direct
Acetyl-CoA synthetase-like0Direct
Methionine aminopeptidase, insert domain0Direct
Pancreatic carboxypeptidase, activation domain0Direct
Pumilio repeat0Direct
Glycolipid transfer protein, GLTP0Direct
POU-specific domain0Direct
Thyroglobulin type-1 domain0Direct
alpha-Amylases, C-terminal beta-sheet domain0Direct
Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain0Direct
BAR domain0Direct
Trunk domain of Sec23/240Direct
CAT-like0Direct
Ras-binding domain, RBD0Direct
Dual specificity phosphatase-like0Direct
PLC-like (P variant)0Direct
t-snare proteins0Direct
L30e/L7ae ribosomal proteins0Direct
Cell cycle control phosphatase, catalytic domain0Direct
Inositol polyphosphate kinase (IPK)0Direct
ARID domain0Direct
D-aminoacid oxidase-like0Direct
DNA replication initiator (cdc21/cdc54) N-terminal domain0Direct
SAND domain0Direct
Nop domain0Direct
Nucleoside diphosphate kinase, NDK0Direct
Peptidylglycine alpha-hydroxylating monooxygenase, PHM0Direct
NTF2-like0Direct
Cofilin-like0Direct
Cation efflux protein cytoplasmic domain-like0Direct
Hormone receptor domain0Direct
Matrix metalloproteases, catalytic domain0Direct
Domain of poly(ADP-ribose) polymerase0Direct
PUA domain0Direct
Translation initiation factor eIF4e0Direct
Alcohol dehydrogenase-like, N-terminal domain0Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0Direct
MFPT repeat0Direct
Helical domain of Sec23/240Direct
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit0Direct
PDZ domain0Direct
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain0Direct
MIF4G domain-like0Direct
Pleckstrin-homology domain (PH domain)0Direct
p120GAP domain-like0Direct
Bacterial exopeptidase dimerisation domain0Direct
Branched-chain alpha-keto acid dehydrogenase Pyr module0Direct
LacY-like proton/sugar symporter0Direct
Sec63 N-terminal domain0Direct
Cytoplasmic domain of inward rectifier potassium channel0Direct
Doublecortin (DC)0Direct
BC ATP-binding domain-like0Direct
Biotinyl/lipoyl-carrier proteins and domains0Direct
Ribosomal protein S180Direct
Tryptophan synthase beta subunit-like PLP-dependent enzymes0Direct
Group II chaperonin (CCT, TRIC), intermediate domain0Direct
Cullin homology domain0Direct
DNA repair protein MutS, domain III0Direct
Aromatic aminoacid monoxygenases, catalytic and oligomerization domains0Direct
Heat shock protein 70kD (HSP70), peptide-binding domain0Direct
Phoshoinositide 3-kinase (PI3K) helical domain0Direct
PDEase0Direct
Paired domain0Direct
Third domain of FERM0Direct
UDP-glucose pyrophosphorylase0Direct
Chaperone J-domain0Direct
RNA-polymerase beta0Direct
Proprotein convertase P-domain0Direct
Spectrin repeat0Direct
PABC (PABP) domain0Direct
Epoxide hydrolase0Direct
Quinoprotein alcohol dehydrogenase-like0Direct
Poly(ADP-ribose) polymerase, C-terminal domain0Direct
GAS2 domain0Direct
Histone deacetylase, HDAC0Direct
LDH N-terminal domain-like0Direct
Eps15 homology domain (EH domain)0Direct
Tubulin, GTPase domain0Direct
HAT/Suf repeat0Direct
BC N-terminal domain-like0Direct
YWTD domain0Direct
Aquaporin-like0Direct
Smc hinge domain0Direct
SWIRM domain0Direct
Anticodon-binding domain0Direct
First domain of FERM0Direct
Troponin I0Direct
WGR domain0Direct
Laminin G-like module0Direct
Acyl-carrier protein (ACP)0Direct
Lesion bypass DNA polymerase (Y-family), catalytic domain0Direct
Lesion bypass DNA polymerase (Y-family), little finger domain0Direct
alpha-mannosidase, domain 20Direct
PurM C-terminal domain-like0Direct
Heme-dependent catalases0Direct
Retrovirus zinc finger-like domains0Direct
Arfaptin, Rac-binding fragment0Direct
Acyl-CoA thioesterase0Direct
RhoGDI-like0Direct
CUT domain0Direct
FAD-dependent thiol oxidase0Direct
Phosphotyrosine-binding domain (PTB)0Direct
SCF ubiquitin ligase complex WHB domain0Direct
MutT-like0Direct
Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta0Direct
Zn-finger domain of Sec23/240Direct
Annexin0Direct
Rap/Ran-GAP0Direct
Heat shock protein 90, HSP90, N-terminal domain0Direct
Polo-box duplicated region0Direct
Choline kinase0Direct
U-box0Direct
ets domain0Direct
Lactate & malate dehydrogenases, C-terminal domain0Direct
Myeloperoxidase-like0Direct
YbiA-like0Direct
Calpain large subunit, catalytic domain (domain II)0Direct
Hsp90 middle domain0Direct
DEATH domain, DD0Direct
alpha-mannosidase, C-terminal domain0Direct
SMAD domain0Direct
Integrin domains0Direct
Hydantoinase (dihydropyrimidinase), catalytic domain0Direct
NHL repeat0Direct
Glycosyl transferases group 10Direct
Poly(A) polymerase, PAP, C-terminal domain0Direct
C-terminal, gelsolin-like domain of Sec23/240Direct
Phosphoglucomutase, first 3 domains0Direct
Phosphoribosyltransferases (PRTases)0Direct
UBA domain0Direct
DEP domain0Direct
2Fe-2S ferredoxin domains from multidomain proteins0Direct
CO dehydrogenase flavoprotein N-terminal domain-like0Direct
Brix domain0Direct
Glutaminase0Direct
HSP200Direct
5' to 3' exonuclease, C-terminal subdomain0Direct
S-adenosylmethionine synthetase0Direct
ATP-dependent protease Lon (La), catalytic domain0Direct
cAMP-binding domain0Direct
Pyk2-associated protein beta ARF-GAP domain0Direct
Subtilases0Direct
Inositol monophosphatase/fructose-1,6-bisphosphatase-like0Direct
Transducin (alpha subunit), insertion domain0Direct
Biotin dependent carboxylase carboxyltransferase domain0Direct
AN1-like Zinc finger0Direct
Adenain-like0Direct
alpha-catenin/vinculin0Direct
Hexokinase0Direct
Hydantoinase (dihydropyrimidinase)0Direct
Hypothetical protein c14orf129, hspc2100Direct
Reprolysin-like0Direct
Myotubularin-like phosphatases0Direct
Regulator of chromosome condensation RCC10Direct
Ferredoxin reductase FAD-binding domain-like0Direct
Linker histone H1/H50Direct
CRAL/TRIO N-terminal domain0Direct
IF2B-like0Direct
Citrate synthase0Direct
Cdc48 domain 2-like0Direct
Lipovitellin-phosvitin complex; beta-sheet shell regions0Direct
Tetraspanin0Direct
GAPDH-like0Direct
Group II chaperonin (CCT, TRIC), ATPase domain0Direct
Sec1/munc18-like (SM) proteins0Direct
PEP carboxykinase C-terminal domain0Direct
Type II chitinase0Direct
Bactericidal permeability-increasing protein, BPI0Direct
Succinyl-CoA synthetase domains0Direct
Erythroid transcription factor GATA-10Direct
Proteasome subunits0Direct
Glycerophosphoryl diester phosphodiesterase0Direct
acyl-CoA oxidase N-terminal domains0Direct
Single strand DNA-binding domain, SSB0Direct
Thiolase-related0Direct
HD domain0Direct
Oxysterol-binding protein0Direct
Tandem AAA-ATPase domain0.002575Inherited
ABC transporter ATPase domain-like0.007482Inherited
Homeodomain0.02783Inherited
G proteins0.03312Inherited
WD40-repeat0.03433Inherited
ABC transporter transmembrane region0.03603Inherited
SH3-domain0.06044Inherited
CCCH zinc finger0.07548Inherited
Canonical RBD0.07909Inherited
Extended AAA-ATPase domain0.08921Inherited
Tetratricopeptide repeat (TPR)0.09709Inherited
Motor proteins0.1153Inherited
HLH, helix-loop-helix DNA-binding domain0.1153Inherited
Calcium ATPase, transduction domain A0.1565Inherited
Cyclin0.1925Inherited
DBL homology domain (DH-domain)0.1925Inherited
Class I aminoacyl-tRNA synthetases (RS), catalytic domain0.1925Inherited
Elongation factors0.1925Inherited
HMG-box0.1925Inherited
Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain0.1925Inherited
Pepsin-like0.2132Inherited
Cytochrome P4500.2308Inherited
Forkhead DNA-binding domain0.2358Inherited
Metal cation-transporting ATPase, ATP-binding domain N0.2358Inherited
Multidrug efflux transporter AcrB transmembrane domain0.2399Inherited
Acetylcholinesterase-like0.2585Inherited
6-phosphogluconate dehydrogenase-like, N-terminal domain0.261Inherited
Bromodomain0.261Inherited
Ankyrin repeat0.2781Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.2781Inherited
FAD/NAD-linked reductases, N-terminal and central domains0.2885Inherited
Crotonase-like0.3191Inherited
Sm motif of small nuclear ribonucleoproteins, SNRNP0.3191Inherited
Meta-cation ATPase, catalytic domain P0.3191Inherited
PX domain0.3533Inherited
BTB/POZ domain0.3864Inherited
Protein kinase cysteine-rich domain (cys2, phorbol-binding domain)0.4017Inherited
Cation efflux protein transmembrane domain-like0.4292Inherited
FKBP immunophilin/proline isomerase0.4292Inherited
PHD domain0.4315Inherited
Glutathione S-transferase (GST), N-terminal domain0.4541Inherited
Nicotinic receptor ligand binding domain-like0.465Inherited
Pyridoxal-dependent decarboxylase0.4714Inherited
Hect, E3 ligase catalytic domain0.4714Inherited
I set domains0.4916Inherited
Papain-like0.496Inherited
Calpain large subunit, middle domain (domain III)0.5196Inherited
Gastric lipase0.5196Inherited
Myb/SANT domain0.5196Inherited
Protein kinases, catalytic subunit0.5383Inherited
UBC-related0.5482Inherited
WW domain0.5573Inherited
Class I alpha-1;2-mannosidase, catalytic domain0.5687Inherited
SH2 domain0.5729Inherited
Synaptotagmin-like (S variant)0.5926Inherited
Ubiquitin carboxyl-terminal hydrolase, UCH0.6347Inherited
Frizzled cysteine-rich domain0.6893Inherited
Transforming growth factor (TGF)-beta0.6893Inherited
EF-hand modules in multidomain proteins0.6893Inherited
Ubiquitin-related0.7133Inherited
Voltage-gated potassium channels0.7449Inherited
H-NOX domain0.7563Inherited
Cdc48 N-terminal domain-like0.7563Inherited
Hemocyanin middle domain0.7563Inherited
MIT domain0.7563Inherited
Bacterial lipase0.7563Inherited
LIM domain0.8231Inherited
AAT-like0.8231Inherited
Cyclophilin (peptidylprolyl isomerase)0.8408Inherited
Glutathione S-transferase (GST), C-terminal domain0.8608Inherited
Calmodulin-like0.8723Inherited
Leucine zipper domain0.8802Inherited
Extended PAW domain0.8947Inherited
SNF-like0.8947Inherited
Thioltransferase0.9207Inherited
Adenylyl and guanylyl cyclase catalytic domain0.9356Inherited
Ribonuclease PH domain 1-like0.9358Inherited
Ribonuclease PH domain 2-like0.9358Inherited
L-arabinose binding protein-like0.9585Inherited
Cold shock DNA-binding domain-like0.988Inherited
Choline/Carnitine O-acyltransferase0.9881Inherited
GABA-aminotransferase-like1Inherited
Histone lysine methyltransferases1Inherited
N-acetyl transferase, NAT1Inherited
B-box zinc-binding domain1Inherited
Nuclear receptor1Inherited
Medium chain acyl-CoA dehydrogenase-like, C-terminal domain1Inherited
Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains1Inherited
Insulin-like1Inherited
MSP-like1Inherited
Nuclear receptor ligand-binding domain1Inherited
Double-stranded RNA-binding domain (dsRBD)1Inherited
PAZ domain1Inherited
RING finger domain, C3HC41Inherited
Rhodopsin-like1Inherited
F-box domain1Inherited
Glutathione peroxidase-like1Inherited
DnaQ-like 3'-5' exonuclease1Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Nucleotidyltransferase0Direct
PurM N-terminal domain-like0Direct
Phosphoenolpyruvate/pyruvate domain0Direct
Ribosomal protein L10-like0Direct
Clathrin adaptor appendage domain0Direct
Annexin0Direct
Lipovitellin-phosvitin complex; beta-sheet shell regions0Direct
Troponin coil-coiled subunits0Direct
Intermediate filament protein, coiled coil region0Direct
Families 57/38 glycoside transferase middle domain0Direct
ALDH-like0Direct
Cytochrome c0Direct
PEP carboxykinase N-terminal domain0Direct
PEBP-like0Direct
Pentein0Direct
WWE domain0Direct
Integrin domains0Direct
Tubby C-terminal domain-like0Direct
Cu,Zn superoxide dismutase-like0Direct
Bacterial exopeptidase dimerisation domain0Direct
Phoshotransferase/anion transport protein0Direct
Rudiment single hybrid motif0Direct
14-3-3 protein0Direct
Proton glutamate symport protein0Direct
FtsH protease domain-like0Direct
LEM domain0Direct
TK C-terminal domain-like0Direct
Ferritin-like0Direct
Putative DNA-binding domain0Direct
SWIB/MDM2 domain0Direct
SAICAR synthase-like0Direct
Thyroglobulin type-1 domain0Direct
HSP90 C-terminal domain0Direct
Glycolipid transfer protein, GLTP0Direct
GroES-like0Direct
Citrate synthase0Direct
Lesion bypass DNA polymerase (Y-family), little finger domain0Direct
DEATH domain0Direct
PYP-like sensor domain (PAS domain)0Direct
Translational machinery components0Direct
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0Direct
GroEL-intermediate domain like0Direct
CO dehydrogenase ISP C-domain like0Direct
Class I glutamine amidotransferase-like0Direct
Tubulin nucleotide-binding domain-like0Direct
Lipovitellin-phosvitin complex, superhelical domain0Direct
Actin-like ATPase domain0Direct
DnaJ/Hsp40 cysteine-rich domain0Direct
Aldolase0Direct
Cystatin/monellin0Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0Direct
GAS2 domain-like0Direct
DNA ligase/mRNA capping enzyme, catalytic domain0Direct
JAB1/MPN domain0Direct
PLP-binding barrel0Direct
Chaperone J-domain0Direct
SPOC domain-like0Direct
ADP-ribosylation0Direct
Complement control module/SCR domain0Direct
MgtE membrane domain-like0Direct
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Thiolase-like0Direct
Glutathione synthetase ATP-binding domain-like0Direct
Ribosomal protein S180Direct
eIF4e-like0Direct
Ribulose-phoshate binding barrel0Direct
Retrovirus zinc finger-like domains0Direct
PK beta-barrel domain-like0Direct
Sec1/munc18-like (SM) proteins0Direct
Acid phosphatase/Vanadium-dependent haloperoxidase0Direct
Second domain of FERM0Direct
GAT-like domain0Direct
PIN domain-like0Direct
Diaminopimelate epimerase-like0Direct
Pepsin inhibitor-30Direct
Chitinase insertion domain0Direct
Aquaporin-like0Direct
ArfGap/RecO-like zinc finger0Direct
Doublecortin (DC)0Direct
FAD-dependent thiol oxidase0Direct
Surp module (SWAP domain)0Direct
PurM C-terminal domain-like0Direct
Tubulin C-terminal domain-like0Direct
HSP20-like chaperones0Direct
Tryptophan synthase beta subunit-like PLP-dependent enzymes0Direct
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit0Direct
Molybdenum cofactor biosynthesis proteins0Direct
Nop domain0Direct
Succinyl-CoA synthetase domains0Direct
CAD & PB1 domains0Direct
Cullin repeat-like0Direct
alpha-catenin/vinculin-like0Direct
Tricorn protease domain 20Direct
MFPT repeat-like0Direct
Helical domain of Sec23/240Direct
Mitochondrial carrier0Direct
HCP-like0Direct
t-snare proteins0Direct
Phosphoglucomutase, first 3 domains0Direct
GroEL equatorial domain-like0Direct
FF domain0Direct
ACP-like0Direct
GYF domain0Direct
Nucleoside diphosphate kinase, NDK0Direct
HRDC-like0Direct
ENTH/VHS domain0Direct
Heat shock protein 70kD (HSP70), C-terminal subdomain0Direct
Carboxypeptidase regulatory domain-like0Direct
cAMP-binding domain-like0Direct
Single hybrid motif0Direct
Carbon-nitrogen hydrolase0Direct
PAP/Archaeal CCA-adding enzyme, C-terminal domain0Direct
Galactose oxidase, central domain0Direct
beta-lactamase/transpeptidase-like0Direct
ThrRS/AlaRS common domain0Direct
Invertebrate chitin-binding proteins0Direct
Ribosomal L27 protein-like0Direct
CBD9-like0Direct
Galactose mutarotase-like0Direct
Tim10-like0Direct
ValRS/IleRS/LeuRS editing domain0Direct
Transducin (alpha subunit), insertion domain0Direct
Ribosomal protein S100Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase0Direct
Elafin-like0Direct
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain0Direct
Zn-binding ribosomal proteins0Direct
Skp1 dimerisation domain-like0Direct
Cadherin-like0Direct
Terpenoid synthases0Direct
Radical SAM enzymes0Direct
Cdc48 domain 2-like0Direct
Protease propeptides/inhibitors0Direct
Band 7/SPFH domain0Direct
GroEL apical domain-like0Direct
Isocitrate/Isopropylmalate dehydrogenase-like0Direct
Spectrin repeat0Direct
Creatinase/prolidase N-terminal domain0Direct
S-adenosylmethionine synthetase0Direct
SAND domain-like0Direct
Sec7 domain0Direct
NagB/RpiA/CoA transferase-like0Direct
Aminoacid dehydrogenase-like, N-terminal domain0Direct
Subtilisin-like0Direct
Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase)0Direct
Hormone receptor domain0Direct
Aromatic aminoacid monoxygenases, catalytic and oligomerization domains0Direct
Heme-dependent peroxidases0Direct
PLC-like phosphodiesterases0Direct
TGS-like0Direct
PAP/OAS1 substrate-binding domain0Direct
L30e-like0Direct
Hedgehog/intein (Hint) domain0Direct
PHM/PNGase F0Direct
PABC (PABP) domain0Direct
MOSC N-terminal domain-like0Direct
ISP domain0Direct
Rap/Ran-GAP0Direct
RBP11-like subunits of RNA polymerase0Direct
Clc chloride channel0Direct
alpha/beta knot0Direct
PreATP-grasp domain0Direct
Phosphoglucomutase, C-terminal domain0Direct
Sec63 N-terminal domain-like0Direct
Lamin A/C globular tail domain0Direct
SMAD MH1 domain0Direct
Molybdenum cofactor-binding domain0Direct
Carbohydrate phosphatase0Direct
CRAL/TRIO N-terminal domain0Direct
Smc hinge domain0Direct
Cullin homology domain0Direct
Hypothetical protein c14orf129, hspc2100Direct
AN1-like Zinc finger0Direct
Activating enzymes of the ubiquitin-like proteins0Direct
CO dehydrogenase molybdoprotein N-domain-like0Direct
Profilin (actin-binding protein)0Direct
C-terminal, gelsolin-like domain of Sec23/240Direct
Histone-fold0Direct
Terpenoid cyclases/Protein prenyltransferases0Direct
FAD-linked oxidases, C-terminal domain0Direct
ARID-like0Direct
Epsilon subunit of mitochondrial F1F0-ATP synthase0Direct
Subdomain of clathrin and coatomer appendage domain0Direct
5' to 3' exonuclease, C-terminal subdomain0Direct
Ribosomal proteins S24e, L23 and L15e0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Cation efflux protein cytoplasmic domain-like0Direct
Transducin (heterotrimeric G protein), gamma chain0Direct
Composite domain of metallo-dependent hydrolases0Direct
Class II aaRS ABD-related0Direct
R3H domain0Direct
Small-conductance potassium channel0Direct
Restriction endonuclease-like0Direct
Thiamin diphosphate-binding fold (THDP-binding)0Direct
Zn-finger domain of Sec23/240Direct
Nucleoporin domain0Direct
FAD/NAD-linked reductases, dimerisation (C-terminal) domain0Direct
2Fe-2S ferredoxin-like0Direct
WGR domain-like0Direct
Fibrinogen C-terminal domain-like0Direct
MIR domain0Direct
L-aspartase-like0Direct
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0Direct
Oxysterol-binding protein-like0Direct
Polo-box domain0Direct
3-carboxy-cis,cis-mucoante lactonizing enzyme0Direct
YbiA-like0Direct
FAD-binding/transporter-associated domain-like0Direct
F1F0 ATP synthase subunit C0Direct
Chromo domain-like0Direct
Ribokinase-like0Direct
Heme-dependent catalase-like0Direct
Ribosomal protein L10Direct
Heat shock protein 70kD (HSP70), peptide-binding domain0Direct
Periplasmic binding protein-like II0Direct
SIS domain0Direct
Ran binding protein zinc finger-like0Direct
Integrin alpha N-terminal domain0Direct
PEP carboxykinase-like0Direct
DNA repair protein MutS, domain III0Direct
Blood coagulation inhibitor (disintegrin)0Direct
Acetyl-CoA synthetase-like0Direct
VPS9 domain0Direct
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0Direct
Outer arm dynein light chain 10Direct
BEACH domain0Direct
Formate/glycerate dehydrogenase catalytic domain-like0Direct
PGBD-like0Direct
LDH C-terminal domain-like0Direct
lambda repressor-like DNA-binding domains0Direct
LysM domain0Direct
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain0Direct
HSP40/DnaJ peptide-binding domain0Direct
Domain of poly(ADP-ribose) polymerase0Direct
Arginase/deacetylase0Direct
YWTD domain0Direct
PH domain-like0.00001044Direct
PDZ domain-like0.006149Inherited
TPR-like0.008382Inherited
ARM repeat0.01204Inherited
ABC transporter transmembrane region0.01495Inherited
SH3-domain0.03519Inherited
Homeodomain-like0.03632Inherited
WD40 repeat-like0.04264Inherited
CCCH zinc finger0.05551Inherited
Translation proteins0.07024Inherited
"Winged helix" DNA-binding domain0.07068Inherited
HLH, helix-loop-helix DNA-binding domain0.08068Inherited
SMAD/FHA domain0.08858Inherited
Calcium ATPase, transmembrane domain M0.09956Inherited
EGF/Laminin0.1071Inherited
Metal cation-transporting ATPase, ATP-binding domain N0.1119Inherited
Regulator of G-protein signaling, RGS0.1119Inherited
Acid proteases0.1257Inherited
Calcium ATPase, transduction domain A0.1257Inherited
Cysteine-rich domain0.1298Inherited
Quinoprotein alcohol dehydrogenase-like0.1407Inherited
Multidrug efflux transporter AcrB transmembrane domain0.1422Inherited
Cytochrome P4500.1463Inherited
(Trans)glycosidases0.1557Inherited
P-loop containing nucleoside triphosphate hydrolases0.1574Inherited
HMG-box0.158Inherited
DBL homology domain (DH-domain)0.158Inherited
ClpP/crotonase0.158Inherited
Ankyrin repeat0.1678Inherited
Cysteine proteinases0.1979Inherited
POZ domain0.2033Inherited
Cyclin-like0.2044Inherited
Bromodomain0.2221Inherited
Tudor/PWWP/MBT0.2221Inherited
6-phosphogluconate dehydrogenase C-terminal domain-like0.2221Inherited
Metallo-dependent phosphatases0.2352Inherited
RNA-binding domain, RBD0.2387Inherited
Lipocalins0.243Inherited
SNARE-like0.2486Inherited
PX domain0.3116Inherited
Cation efflux protein transmembrane domain-like0.3116Inherited
Nicotinic receptor ligand binding domain-like0.3168Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.3558Inherited
RNI-like0.3715Inherited
HD-domain/PDEase-like0.3869Inherited
FKBP-like0.3869Inherited
Class II aaRS and biotin synthetases0.3977Inherited
DHS-like NAD/FAD-binding domain0.4309Inherited
Myosin rod fragments0.4309Inherited
PRTase-like0.4309Inherited
Hect, E3 ligase catalytic domain0.4309Inherited
Galactose-binding domain-like0.4508Inherited
SH2 domain0.452Inherited
Sm-like ribonucleoproteins0.4624Inherited
Cystine-knot cytokines0.4624Inherited
Voltage-gated potassium channels0.4761Inherited
Calpain large subunit, middle domain (domain III)0.479Inherited
Riboflavin synthase domain-like0.479Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.479Inherited
WW domain0.4964Inherited
UBC-like0.4982Inherited
SAM/Pointed domain0.4995Inherited
Protein kinase-like (PK-like)0.5038Inherited
Seven-hairpin glycosidases0.5337Inherited
Multidrug resistance efflux transporter EmrE0.5352Inherited
C2 domain (Calcium/lipid-binding domain, CaLB)0.555Inherited
S-adenosyl-L-methionine-dependent methyltransferases0.586Inherited
Di-copper centre-containing domain0.5896Inherited
KA1-like0.5896Inherited
HIT/MYND zinc finger-like0.6102Inherited
GST C-terminal domain-like0.637Inherited
DNase I-like0.6528Inherited
S15/NS1 RNA-binding domain0.6557Inherited
4Fe-4S ferredoxins0.6557Inherited
Frizzled cysteine-rich domain0.6557Inherited
alpha/beta-Hydrolases0.6764Inherited
Fibronectin type III0.7107Inherited
MIT domain0.728Inherited
ADC-like0.728Inherited
Clavaminate synthase-like0.7715Inherited
NAD kinase/diacylglycerol kinase-like0.7839Inherited
Cyclophilin-like0.79Inherited
CoA-dependent acyltransferases0.79Inherited
EF-hand0.8057Inherited
SNF-like0.8213Inherited
Leucine zipper domain0.8249Inherited
Eukaryotic type KH-domain (KH-domain type I)0.8315Inherited
GTPase activation domain, GAP0.8315Inherited
Ubiquitin-like0.8319Inherited
Thioredoxin-like0.8443Inherited
Ribonuclease H-like0.8672Inherited
Immunoglobulin0.8729Inherited
p53-like transcription factors0.876Inherited
Nucleic acid-binding proteins0.8805Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.8863Inherited
MFS general substrate transporter0.895Inherited
FYVE/PHD zinc finger0.9003Inherited
Nucleotide-diphospho-sugar transferases0.9025Inherited
HAD-like0.9096Inherited
Ribonuclease PH domain 2-like0.9123Inherited
Saposin0.9346Inherited
Periplasmic binding protein-like I0.9362Inherited
FAD/NAD(P)-binding domain0.9362Inherited
PLP-dependent transferases0.9425Inherited
Nucleotide cyclase0.9491Inherited
Ribosomal protein S5 domain 2-like0.9582Inherited
SET domain0.9655Inherited
PAZ domain0.9724Inherited
Ligand-binding domain in the NO signalling and Golgi transport0.9868Inherited
Acyl-CoA dehydrogenase C-terminal domain-like0.9913Inherited
Acyl-CoA dehydrogenase NM domain-like0.9913Inherited
Nucleotidylyl transferase0.9913Inherited
beta-beta-alpha zinc fingers1Inherited
Insulin-like1Inherited
Translation proteins SH3-like domain1Inherited
UBA-like1Inherited
dsRNA-binding domain-like1Inherited
DNA/RNA polymerases1Inherited
PapD-like1Inherited
B-box zinc-binding domain1Inherited
Nuclear receptor ligand-binding domain1Inherited
Bet v1-like1Inherited
RING/U-box1Inherited
Family A G protein-coupled receptor-like1Inherited
Snake toxin-like1Inherited
F-box domain1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57903,82199
  • 57903 - FYVE/PHD zinc finger
  • 82199 - SET domain
  • 0Direct
    51905,56425
  • 51905 - FAD/NAD(P)-binding domain
  • 56425 - Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain
  • 0Direct
    56672,100879
  • 56672 - DNA/RNA polymerases
  • 100879 - Lesion bypass DNA polymerase (Y-family), little finger domain
  • 0Direct
    82895,82895
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 0Direct
    51735,56327
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 56327 - LDH C-terminal domain-like
  • 0Direct
    54849,52029
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0Direct
    57414,57414
  • 57414 - Hairpin loop containing domain-like
  • 57414 - Hairpin loop containing domain-like
  • 0Direct
    53067,100920
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 0Direct
    56601,48403
  • 56601 - beta-lactamase/transpeptidase-like
  • 48403 - Ankyrin repeat
  • 0Direct
    56112,82615
  • 56112 - Protein kinase-like (PK-like)
  • 82615 - Polo-box domain
  • 0Direct
    161093,161093
  • 161093 - MgtE membrane domain-like
  • 161093 - MgtE membrane domain-like
  • 0Direct
    49493,49493
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 0Direct
    48464,89009
  • 48464 - ENTH/VHS domain
  • 89009 - GAT-like domain
  • 0Direct
    48334,52540
  • 48334 - DNA repair protein MutS, domain III
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    81333,81333
  • 81333 - F1F0 ATP synthase subunit C
  • 81333 - F1F0 ATP synthase subunit C
  • 0Direct
    56968,48431
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 48431 - Lipovitellin-phosvitin complex, superhelical domain
  • 0Direct
    52540,81271
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 81271 - TGS-like
  • 0Direct
    49348,55711
  • 49348 - Clathrin adaptor appendage domain
  • 55711 - Subdomain of clathrin and coatomer appendage domain
  • 0Direct
    47769,47769
  • 47769 - SAM/Pointed domain
  • 47769 - SAM/Pointed domain
  • 0Direct
    50692,54585
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 0Direct
    51206,51206
  • 51206 - cAMP-binding domain-like
  • 51206 - cAMP-binding domain-like
  • 0Direct
    50729,56112
  • 50729 - PH domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    55486,57552
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 57552 - Blood coagulation inhibitor (disintegrin)
  • 0Direct
    81324,81296
  • 81324 - Voltage-gated potassium channels
  • 81296 - E set domains
  • 0Direct
    52540,140990
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 140990 - FtsH protease domain-like
  • 0Direct
    47203,47203
  • 47203 - Acyl-CoA dehydrogenase C-terminal domain-like
  • 47203 - Acyl-CoA dehydrogenase C-terminal domain-like
  • 0Direct
    52113,52113
  • 52113 - BRCT domain
  • 52113 - BRCT domain
  • 0Direct
    81698,81698
  • 81698 - FF domain
  • 81698 - FF domain
  • 0Direct
    56112,48371
  • 56112 - Protein kinase-like (PK-like)
  • 48371 - ARM repeat
  • 0Direct
    51556,51338
  • 51556 - Metallo-dependent hydrolases
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 0Direct
    74788,75632
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 0Direct
    52374,47323
  • 52374 - Nucleotidylyl transferase
  • 47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
  • 0Direct
    81383,52047
  • 81383 - F-box domain
  • 52047 - RNI-like
  • 0Direct
    55973,55973
  • 55973 - S-adenosylmethionine synthetase
  • 55973 - S-adenosylmethionine synthetase
  • 0Direct
    54695,81382
  • 54695 - POZ domain
  • 81382 - Skp1 dimerisation domain-like
  • 0Direct
    52283,51735
  • 52283 - Formate/glycerate dehydrogenase catalytic domain-like
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0Direct
    53187,49464
  • 53187 - Zn-dependent exopeptidases
  • 49464 - Carboxypeptidase regulatory domain-like
  • 0Direct
    81383,50978
  • 81383 - F-box domain
  • 50978 - WD40 repeat-like
  • 0Direct
    52440,56059
  • 52440 - PreATP-grasp domain
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 0Direct
    55729,55729
  • 55729 - Acyl-CoA N-acyltransferases (Nat)
  • 55729 - Acyl-CoA N-acyltransferases (Nat)
  • 0Direct
    50729,47473
  • 50729 - PH domain-like
  • 47473 - EF-hand
  • 0Direct
    50044,52540
  • 50044 - SH3-domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    144232,82199
  • 144232 - HIT/MYND zinc finger-like
  • 82199 - SET domain
  • 0Direct
    54236,54236
  • 54236 - Ubiquitin-like
  • 54236 - Ubiquitin-like
  • 0Direct
    54292,47741
  • 54292 - 2Fe-2S ferredoxin-like
  • 47741 - CO dehydrogenase ISP C-domain like
  • 0Direct
    81324,53850
  • 81324 - Voltage-gated potassium channels
  • 53850 - Periplasmic binding protein-like II
  • 0Direct
    54897,52743
  • 54897 - Protease propeptides/inhibitors
  • 52743 - Subtilisin-like
  • 0Direct
    50129,51735
  • 50129 - GroES-like
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0Direct
    54897,53187
  • 54897 - Protease propeptides/inhibitors
  • 53187 - Zn-dependent exopeptidases
  • 0Direct
    57938,49493
  • 57938 - DnaJ/Hsp40 cysteine-rich domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 0Direct
    50447,50465
  • 50447 - Translation proteins
  • 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
  • 0Direct
    64593,74853
  • 64593 - Intermediate filament protein, coiled coil region
  • 74853 - Lamin A/C globular tail domain
  • 0Direct
    48371,48371
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 0Direct
    51971,54373
  • 51971 - Nucleotide-binding domain
  • 54373 - FAD-linked reductases, C-terminal domain
  • 0Direct
    47576,47576
  • 47576 - Calponin-homology domain, CH-domain
  • 47576 - Calponin-homology domain, CH-domain
  • 0Direct
    51338,51556
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 51556 - Metallo-dependent hydrolases
  • 0Direct
    52540,46785
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    52047,52047
  • 52047 - RNI-like
  • 52047 - RNI-like
  • 0Direct
    50677,52374
  • 50677 - ValRS/IleRS/LeuRS editing domain
  • 52374 - Nucleotidylyl transferase
  • 0Direct
    47741,56176
  • 47741 - CO dehydrogenase ISP C-domain like
  • 56176 - FAD-binding/transporter-associated domain-like
  • 0Direct
    54585,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    51695,49562
  • 51695 - PLC-like phosphodiesterases
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0Direct
    50249,50249
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 0Direct
    81301,81631
  • 81301 - Nucleotidyltransferase
  • 81631 - PAP/OAS1 substrate-binding domain
  • 0Direct
    90229,90229
  • 90229 - CCCH zinc finger
  • 90229 - CCCH zinc finger
  • 0Direct
    46785,46785
  • 46785 - "Winged helix" DNA-binding domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    54160,54160
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 0Direct
    56176,55103
  • 56176 - FAD-binding/transporter-associated domain-like
  • 55103 - FAD-linked oxidases, C-terminal domain
  • 0Direct
    48403,52151
  • 48403 - Ankyrin repeat
  • 52151 - FabD/lysophospholipase-like
  • 0Direct
    56059,52210
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 52210 - Succinyl-CoA synthetase domains
  • 0Direct
    50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0Direct
    47031,50729
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0Direct
    81811,82754
  • 81811 - Helical domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0Direct
    57196,49899
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    82919,53300
  • 82919 - Zn-finger domain of Sec23/24
  • 53300 - vWA-like
  • 0Direct
    57184,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0Direct
    52518,52518
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 0Direct
    57889,48350
  • 57889 - Cysteine-rich domain
  • 48350 - GTPase activation domain, GAP
  • 0Direct
    75632,46785
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    100950,100950
  • 100950 - NagB/RpiA/CoA transferase-like
  • 100950 - NagB/RpiA/CoA transferase-like
  • 0Direct
    51445,54556
  • 51445 - (Trans)glycosidases
  • 54556 - Chitinase insertion domain
  • 0Direct
    49742,49742
  • 49742 - PHM/PNGase F
  • 49742 - PHM/PNGase F
  • 0Direct
    46938,52087
  • 46938 - CRAL/TRIO N-terminal domain
  • 52087 - CRAL/TRIO domain
  • 0Direct
    57756,57756
  • 57756 - Retrovirus zinc finger-like domains
  • 57756 - Retrovirus zinc finger-like domains
  • 0Direct
    47090,55486
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0Direct
    53738,53738
  • 53738 - Phosphoglucomutase, first 3 domains
  • 53738 - Phosphoglucomutase, first 3 domains
  • 0Direct
    47954,47954
  • 47954 - Cyclin-like
  • 47954 - Cyclin-like
  • 0Direct
    54001,49758
  • 54001 - Cysteine proteinases
  • 49758 - Calpain large subunit, middle domain (domain III)
  • 0Direct
    48179,48179
  • 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
  • 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
  • 0Direct
    82615,82615
  • 82615 - Polo-box domain
  • 82615 - Polo-box domain
  • 0Direct
    49265,48726
  • 49265 - Fibronectin type III
  • 48726 - Immunoglobulin
  • 0Direct
    56059,51246
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 51246 - Rudiment single hybrid motif
  • 0Direct
    55681,52954
  • 55681 - Class II aaRS and biotin synthetases
  • 52954 - Class II aaRS ABD-related
  • 0Direct
    52743,49785
  • 52743 - Subtilisin-like
  • 49785 - Galactose-binding domain-like
  • 0Direct
    161111,160240
  • 161111 - Cation efflux protein transmembrane domain-like
  • 160240 - Cation efflux protein cytoplasmic domain-like
  • 0Direct
    53738,55957
  • 53738 - Phosphoglucomutase, first 3 domains
  • 55957 - Phosphoglucomutase, C-terminal domain
  • 0Direct
    53067,53067
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 0Direct
    47473,51695
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 0Direct
    53901,53901
  • 53901 - Thiolase-like
  • 53901 - Thiolase-like
  • 0Direct
    50156,50044
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 0Direct
    88713,88688
  • 88713 - Glycoside hydrolase/deacetylase
  • 88688 - Families 57/38 glycoside transferase middle domain
  • 0Direct
    55326,56042
  • 55326 - PurM N-terminal domain-like
  • 56042 - PurM C-terminal domain-like
  • 0Direct
    47220,47220
  • 47220 - alpha-catenin/vinculin-like
  • 47220 - alpha-catenin/vinculin-like
  • 0Direct
    141739,141739
  • 141739 - MFPT repeat-like
  • 141739 - MFPT repeat-like
  • 0Direct
    47895,52540
  • 47895 - Transducin (alpha subunit), insertion domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    57889,57889
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 0Direct
    57625,57625
  • 57625 - Invertebrate chitin-binding proteins
  • 57625 - Invertebrate chitin-binding proteins
  • 0Direct
    55394,55394
  • 55394 - Bactericidal permeability-increasing protein, BPI
  • 55394 - Bactericidal permeability-increasing protein, BPI
  • 0Direct
    54236,47031
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 0Direct
    57850,117839
  • 57850 - RING/U-box
  • 117839 - WWE domain
  • 0Direct
    81324,81327
  • 81324 - Voltage-gated potassium channels
  • 81327 - Small-conductance potassium channel
  • 0Direct
    50978,50998
  • 50978 - WD40 repeat-like
  • 50998 - Quinoprotein alcohol dehydrogenase-like
  • 0Direct
    57196,63825
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 0Direct
    100920,100934
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
  • 0Direct
    46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0Direct
    54211,55060
  • 54211 - Ribosomal protein S5 domain 2-like
  • 55060 - GHMP Kinase, C-terminal domain
  • 0Direct
    57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0Direct
    51905,55424
  • 51905 - FAD/NAD(P)-binding domain
  • 55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain
  • 0Direct
    52518,52922
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 52922 - TK C-terminal domain-like
  • 0Direct
    68923,53795
  • 68923 - PEP carboxykinase N-terminal domain
  • 53795 - PEP carboxykinase-like
  • 0Direct
    54665,56003
  • 54665 - CO dehydrogenase molybdoprotein N-domain-like
  • 56003 - Molybdenum cofactor-binding domain
  • 0Direct
    57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0Direct
    56091,50249
  • 56091 - DNA ligase/mRNA capping enzyme, catalytic domain
  • 50249 - Nucleic acid-binding proteins
  • 0Direct
    81631,55003
  • 81631 - PAP/OAS1 substrate-binding domain
  • 55003 - PAP/Archaeal CCA-adding enzyme, C-terminal domain
  • 0Direct
    54495,46934
  • 54495 - UBC-like
  • 46934 - UBA-like
  • 0Direct
    55785,55785
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0Direct
    74650,51445
  • 74650 - Galactose mutarotase-like
  • 51445 - (Trans)glycosidases
  • 0Direct
    48371,56112
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    48592,54849
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 0Direct
    48425,50729
  • 48425 - Sec7 domain
  • 50729 - PH domain-like
  • 0Direct
    51735,55347
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 55347 - Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain
  • 0Direct
    52490,55307
  • 52490 - Tubulin nucleotide-binding domain-like
  • 55307 - Tubulin C-terminal domain-like
  • 0Direct
    57863,48403
  • 57863 - ArfGap/RecO-like zinc finger
  • 48403 - Ankyrin repeat
  • 0Direct
    48065,50729
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0Direct
    57362,57362
  • 57362 - BPTI-like
  • 57362 - BPTI-like
  • 0Direct
    141673,50800
  • 141673 - MOSC N-terminal domain-like
  • 50800 - PK beta-barrel domain-like
  • 0Direct
    47587,56399
  • 47587 - Domain of poly(ADP-ribose) polymerase
  • 56399 - ADP-ribosylation
  • 0Direct
    47473,103506
  • 47473 - EF-hand
  • 103506 - Mitochondrial carrier
  • 0Direct
    64356,49447
  • 64356 - SNARE-like
  • 49447 - Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor
  • 0Direct
    51445,51011
  • 51445 - (Trans)glycosidases
  • 51011 - Glycosyl hydrolase domain
  • 0Direct
    57889,50729
  • 57889 - Cysteine-rich domain
  • 50729 - PH domain-like
  • 0Direct
    55486,50923
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 0Direct
    54534,54534
  • 54534 - FKBP-like
  • 54534 - FKBP-like
  • 0Direct
    48431,56968
  • 48431 - Lipovitellin-phosvitin complex, superhelical domain
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 0Direct
    54768,54768
  • 54768 - dsRNA-binding domain-like
  • 54768 - dsRNA-binding domain-like
  • 0Direct
    55920,46785
  • 55920 - Creatinase/aminopeptidase
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    52540,90123
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 90123 - ABC transporter transmembrane region
  • 0Direct
    49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0Direct
    57903,51197
  • 57903 - FYVE/PHD zinc finger
  • 51197 - Clavaminate synthase-like
  • 0Direct
    53187,55031
  • 53187 - Zn-dependent exopeptidases
  • 55031 - Bacterial exopeptidase dimerisation domain
  • 0Direct
    47413,46689
  • 47413 - lambda repressor-like DNA-binding domains
  • 46689 - Homeodomain-like
  • 0Direct
    54160,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    52540,47917
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase
  • 0Direct
    57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0Direct
    49562,48371
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 0Direct
    90123,52540
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.01495Inherited
    48452,48452
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 0.08858Inherited
    52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.1009Inherited
    56112,55073
  • 56112 - Protein kinase-like (PK-like)
  • 55073 - Nucleotide cyclase
  • 0.1119Inherited
    81660,56784
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 0.1119Inherited
    56436,56436
  • 56436 - C-type lectin-like
  • 56436 - C-type lectin-like
  • 0.1143Inherited
    52540,50447
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 0.1772Inherited
    56436,49854
  • 56436 - C-type lectin-like
  • 49854 - Spermadhesin, CUB domain
  • 0.2044Inherited
    51735,48179
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
  • 0.2221Inherited
    56784,81665
  • 56784 - HAD-like
  • 81665 - Calcium ATPase, transmembrane domain M
  • 0.2221Inherited
    50978,50978
  • 50978 - WD40 repeat-like
  • 50978 - WD40 repeat-like
  • 0.2785Inherited
    52833,52833
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 0.2785Inherited
    47473,47473
  • 47473 - EF-hand
  • 47473 - EF-hand
  • 0.3116Inherited
    63712,90112
  • 63712 - Nicotinic receptor ligand binding domain-like
  • 90112 - Neurotransmitter-gated ion-channel transmembrane pore
  • 0.3558Inherited
    54928,54928
  • 54928 - RNA-binding domain, RBD
  • 54928 - RNA-binding domain, RBD
  • 0.369Inherited
    57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.4294Inherited
    52833,47616
  • 52833 - Thioredoxin-like
  • 47616 - GST C-terminal domain-like
  • 0.4697Inherited
    101690,53098
  • 101690 - PAZ domain
  • 53098 - Ribonuclease H-like
  • 0.5337Inherited
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.5337Inherited
    51045,51045
  • 51045 - WW domain
  • 51045 - WW domain
  • 0.5896Inherited
    57903,57903
  • 57903 - FYVE/PHD zinc finger
  • 57903 - FYVE/PHD zinc finger
  • 0.6557Inherited
    50249,55681
  • 50249 - Nucleic acid-binding proteins
  • 55681 - Class II aaRS and biotin synthetases
  • 0.6557Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.6592Inherited
    55550,50044
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0.728Inherited
    48726,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.79Inherited
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.817Inherited
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.8238Inherited
    54211,55666
  • 54211 - Ribosomal protein S5 domain 2-like
  • 55666 - Ribonuclease PH domain 2-like
  • 0.9123Inherited
    49562,49562
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.9139Inherited
    49785,49785
  • 49785 - Galactose-binding domain-like
  • 49785 - Galactose-binding domain-like
  • 0.9409Inherited
    52777,52777
  • 52777 - CoA-dependent acyltransferases
  • 52777 - CoA-dependent acyltransferases
  • 0.9409Inherited
    56645,47203
  • 56645 - Acyl-CoA dehydrogenase NM domain-like
  • 47203 - Acyl-CoA dehydrogenase C-terminal domain-like
  • 0.9913Inherited
    53300,56436
  • 53300 - vWA-like
  • 56436 - C-type lectin-like
  • 1Inherited
    57850,57850
  • 57850 - RING/U-box
  • 57850 - RING/U-box
  • 1Inherited
    57850,57845
  • 57850 - RING/U-box
  • 57845 - B-box zinc-binding domain
  • 1Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    81301,81631,55003
  • 81301 - Nucleotidyltransferase
  • 81631 - PAP/OAS1 substrate-binding domain
  • 55003 - PAP/Archaeal CCA-adding enzyme, C-terminal domain
  • 0Direct
    57535,57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0Direct
    46966,46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0Direct
    49562,48371,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    53738,53738,53738
  • 53738 - Phosphoglucomutase, first 3 domains
  • 53738 - Phosphoglucomutase, first 3 domains
  • 53738 - Phosphoglucomutase, first 3 domains
  • 0Direct
    52540,90123,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    50044,50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0Direct
    57362,57362,57362
  • 57362 - BPTI-like
  • 57362 - BPTI-like
  • 57362 - BPTI-like
  • 0Direct
    74650,51445,51011
  • 74650 - Galactose mutarotase-like
  • 51445 - (Trans)glycosidases
  • 51011 - Glycosyl hydrolase domain
  • 0Direct
    53067,53067,100920
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 0Direct
    50044,55550,56112
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    54236,47031,50729
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0Direct
    56112,82615,82615
  • 56112 - Protein kinase-like (PK-like)
  • 82615 - Polo-box domain
  • 82615 - Polo-box domain
  • 0Direct
    51735,48179,48179
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
  • 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
  • 0Direct
    46938,52087,101576
  • 46938 - CRAL/TRIO N-terminal domain
  • 52087 - CRAL/TRIO domain
  • 101576 - Supernatant protein factor (SPF), C-terminal domain
  • 0Direct
    74788,75632,46785
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    55973,55973,55973
  • 55973 - S-adenosylmethionine synthetase
  • 55973 - S-adenosylmethionine synthetase
  • 55973 - S-adenosylmethionine synthetase
  • 0Direct
    50729,47473,51695
  • 50729 - PH domain-like
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 0Direct
    47090,55486,50923
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 0Direct
    54292,47741,56176
  • 54292 - 2Fe-2S ferredoxin-like
  • 47741 - CO dehydrogenase ISP C-domain like
  • 56176 - FAD-binding/transporter-associated domain-like
  • 0Direct
    57414,57414,57414
  • 57414 - Hairpin loop containing domain-like
  • 57414 - Hairpin loop containing domain-like
  • 57414 - Hairpin loop containing domain-like
  • 0Direct
    49899,49899,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    50692,54585,52540
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    57567,57567,57567
  • 57567 - Serine protease inhibitors
  • 57567 - Serine protease inhibitors
  • 57567 - Serine protease inhibitors
  • 0Direct
    48592,54849,52029
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0Direct
    50156,50044,52540
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    49313,49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0Direct
    52440,56059,51246
  • 52440 - PreATP-grasp domain
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 51246 - Rudiment single hybrid motif
  • 0Direct
    50249,50249,50249
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 0Direct
    57938,49493,49493
  • 57938 - DnaJ/Hsp40 cysteine-rich domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 0Direct
    82895,82895,82895
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 0Direct
    56968,48431,56968
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 48431 - Lipovitellin-phosvitin complex, superhelical domain
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 0Direct
    56645,47203,47203
  • 56645 - Acyl-CoA dehydrogenase NM domain-like
  • 47203 - Acyl-CoA dehydrogenase C-terminal domain-like
  • 47203 - Acyl-CoA dehydrogenase C-terminal domain-like
  • 0Direct
    57625,57625,57625
  • 57625 - Invertebrate chitin-binding proteins
  • 57625 - Invertebrate chitin-binding proteins
  • 57625 - Invertebrate chitin-binding proteins
  • 0Direct
    54585,52540,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    48452,48452,48452
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 0Direct
    52540,52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    53067,100920,100934
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
  • 0Direct
    54897,52743,49785
  • 54897 - Protease propeptides/inhibitors
  • 52743 - Subtilisin-like
  • 49785 - Galactose-binding domain-like
  • 0Direct
    48371,48371,48371
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 0Direct
    56436,49854,49854
  • 56436 - C-type lectin-like
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 0Direct
    90123,52540,90123
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 90123 - ABC transporter transmembrane region
  • 0Direct
    48726,49265,48726
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 48726 - Immunoglobulin
  • 0Direct
    54160,52540,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    53738,53738,55957
  • 53738 - Phosphoglucomutase, first 3 domains
  • 53738 - Phosphoglucomutase, first 3 domains
  • 55957 - Phosphoglucomutase, C-terminal domain
  • 0Direct
    52540,50447,50465
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
  • 0Direct
    54160,54160,52540
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    81660,56784,81665
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 81665 - Calcium ATPase, transmembrane domain M
  • 0.1257Inherited
    56436,56436,49854
  • 56436 - C-type lectin-like
  • 56436 - C-type lectin-like
  • 49854 - Spermadhesin, CUB domain
  • 0.3403Inherited
    57424,57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.3477Inherited
    52833,52833,52833
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 0.3477Inherited
    57716,57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.4309Inherited
    57850,57850,57850
  • 57850 - RING/U-box
  • 57850 - RING/U-box
  • 57850 - RING/U-box
  • 0.8268Inherited
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.9346Inherited
    48726,48726,49265
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.9868Inherited


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