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Worm Phenotype (WP): reproductive system development variant

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Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)

Shortest distance to current term (+ for parents, - for children) WP term [WP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   Variant [WBPhenotype:0000886] <5>
+ + 2:   development variant [WBPhenotype:0000518] <4>(511|586) (511|253|70)
+ 1:   organ system development variant [WBPhenotype:0000530] <9>(78|71) (81|32|12)
0:   reproductive system development variant [WBPhenotype:0000624] <10>(46|39) (47|21|8)
- 1:   vulva development variant [WBPhenotype:0000699] <3>(17|15) (17|3|1)
- 1:   copulatory structure development variant [WBPhenotype:0000429] <2>(0|0) (0|0|0)
- 1:   gonad development variant [WBPhenotype:0000691] <2>(17|14) (18|8|3)
- 1:   sex muscle development variant [WBPhenotype:0000669] <2>(0|0) (0|0|0)
- 1:   vulva uterus connection defective [WBPhenotype:0000283] <2>(9|7) (9|7|3)
- 1:   feminization of XX and XO animals [WBPhenotype:0000687] <1>(1|0) (1|0|0)
- 1:   fewer eggs in utero [WBPhenotype:0002019](0|0) (0|0|0)
- 1:   gonad migration variant [WBPhenotype:0000690](0|1) (0|0|0)
- 1:   no uterus [WBPhenotype:0000401](0|0) (0|0|0)
- 1:   sexual maturation defective [WBPhenotype:0000434](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Integrin alpha N-terminal domain0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Cullin repeat-like0.00003523Direct
Sema domain0.00003903Direct
Plexin repeat0.00003903Direct
Integrin domains0.00009198Direct
Cdc48 domain 2-like0.00009198Direct
E2F-DP heterodimerization region0.00009198Direct
ADC-like0.00009198Direct
Cullin homology domain0.0001236Direct
F1F0 ATP synthase subunit C0.0004073Direct
Immunoglobulin0.0005906Direct
Chromo domain-like0.001072Inherited
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.001888Inherited
Sm-like ribonucleoproteins0.005132Inherited
Bromodomain0.008667Inherited
HMG-box0.02452Inherited
Fibronectin type III0.02619Inherited
FYVE/PHD zinc finger0.03799Inherited
SET domain0.04104Inherited
Acyl-CoA N-acyltransferases (Nat)0.04282Inherited
Cadherin-like0.04375Inherited
EGF/Laminin0.05661Inherited
WD40 repeat-like0.07112Inherited
Cystine-knot cytokines0.07725Inherited
Nucleic acid-binding proteins0.07745Inherited
Cyclin-like0.09435Inherited
GroEL-intermediate domain like0.1128Inherited
GroEL equatorial domain-like0.1128Inherited
GroEL apical domain-like0.1128Inherited
HIT/MYND zinc finger-like0.1848Inherited
Arginase/deacetylase0.1848Inherited
P-loop containing nucleoside triphosphate hydrolases0.1977Inherited
TPR-like0.3414Inherited
Protein kinase-like (PK-like)0.3492Inherited
SNARE-like0.5072Inherited
"Winged helix" DNA-binding domain0.5659Inherited
Nucleotide-diphospho-sugar transferases0.5849Inherited
Homeodomain-like0.9189Inherited
TSP-1 type 1 repeat0.922Inherited
Tubulin nucleotide-binding domain-like0.922Inherited
NAD(P)-binding Rossmann-fold domains0.9422Inherited
F-box domain0.9731Inherited
Tubulin C-terminal domain-like0.9934Inherited
RNA-binding domain, RBD1Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Integrin domains0Direct
PHD domain0.00001003Direct
Sema domain0.00001321Direct
Proteasome subunits0.00001665Direct
Cullin repeat0.0000707Direct
DNA replication initiator (cdc21/cdc54) N-terminal domain0.0000707Direct
SCF ubiquitin ligase complex WHB domain0.0000707Direct
Plexin repeat0.0000707Direct
Cdc48 N-terminal domain-like0.0001416Direct
Cell cycle transcription factor e2f-dp0.0001416Direct
Cdc48 domain 2-like0.0001416Direct
Cullin homology domain0.0002221Direct
F1F0 ATP synthase subunit C0.0006247Direct
Transforming growth factor (TGF)-beta0.0006247Direct
N-acetyl transferase, NAT0.0008007Direct
RecA protein-like (ATPase-domain)0.001674Inherited
Armadillo repeat0.005057Inherited
I set domains0.006735Inherited
Bromodomain0.006735Inherited
Sm motif of small nuclear ribonucleoproteins, SNRNP0.01154Inherited
HMG-box0.01975Inherited
Fibronectin type III0.02075Inherited
Cadherin0.03072Inherited
TBP-associated factors, TAFs0.03072Inherited
Histone lysine methyltransferases0.03373Inherited
Chromo domain0.04046Inherited
Pumilio repeat0.05706Inherited
WD40-repeat0.07297Inherited
Group II chaperonin (CCT, TRIC), ATPase domain0.1623Inherited
Clathrin adaptor core protein0.1623Inherited
Group II chaperonin (CCT, TRIC), apical domain0.1623Inherited
Histone deacetylase, HDAC0.1623Inherited
Protein kinases, catalytic subunit0.3111Inherited
PDZ domain0.4699Inherited
Homeodomain0.8019Inherited
Tubulin, GTPase domain0.9018Inherited
Tubulin, C-terminal domain0.9802Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Integrin alpha N-terminal domain0Direct
Cullin repeat-like0.00002862Direct
Sema domain0.00003172Direct
Plexin repeat0.00003172Direct
Integrin domains0.00007505Direct
Cdc48 domain 2-like0.00007505Direct
ADC-like0.00007505Direct
E2F-DP heterodimerization region0.00007505Direct
Cullin homology domain0.0001009Direct
F1F0 ATP synthase subunit C0.0003349Direct
Immunoglobulin0.0004868Direct
Chromo domain-like0.0008886Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase0.0009085Direct
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.001577Inherited
Sm-like ribonucleoproteins0.004342Inherited
Bromodomain0.007394Inherited
HMG-box0.02135Inherited
Fibronectin type III0.02283Inherited
FYVE/PHD zinc finger0.03332Inherited
SET domain0.03606Inherited
Acyl-CoA N-acyltransferases (Nat)0.03765Inherited
Cadherin-like0.03848Inherited
EGF/Laminin0.05013Inherited
WD40 repeat-like0.06334Inherited
Cystine-knot cytokines0.06894Inherited
Nucleic acid-binding proteins0.06912Inherited
Cyclin-like0.08471Inherited
GroEL apical domain-like0.1018Inherited
GroEL equatorial domain-like0.1018Inherited
GroEL-intermediate domain like0.1018Inherited
Arginase/deacetylase0.1694Inherited
HIT/MYND zinc finger-like0.1694Inherited
P-loop containing nucleoside triphosphate hydrolases0.1816Inherited
TPR-like0.3208Inherited
Protein kinase-like (PK-like)0.3285Inherited
SNARE-like0.4849Inherited
"Winged helix" DNA-binding domain0.5434Inherited
Nucleotide-diphospho-sugar transferases0.5627Inherited
Homeodomain-like0.9061Inherited
TSP-1 type 1 repeat0.9094Inherited
Tubulin nucleotide-binding domain-like0.9094Inherited
NAD(P)-binding Rossmann-fold domains0.9303Inherited
F-box domain0.9629Inherited
Tubulin C-terminal domain-like0.9835Inherited
RNA-binding domain, RBD1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
52540,47917
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase
  • 0Direct
    46785,144074
  • 46785 - "Winged helix" DNA-binding domain
  • 144074 - E2F-DP heterodimerization region
  • 0Direct
    54585,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    50692,54585
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 0Direct
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.00001872Direct
    75632,46785
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0.00003172Direct
    74788,75632
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 0.00003172Direct
    81333,81333
  • 81333 - F1F0 ATP synthase subunit C
  • 81333 - F1F0 ATP synthase subunit C
  • 0.00007505Direct
    101912,103575
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 0.00007505Direct
    55550,50044
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0.00007505Direct
    57903,57903
  • 57903 - FYVE/PHD zinc finger
  • 57903 - FYVE/PHD zinc finger
  • 0.0003349Direct
    54160,54160
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 0.00193Inherited
    49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.0128Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.06912Inherited
    48452,48452
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 0.08471Inherited
    48726,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.08471Inherited
    54849,52029
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.1018Inherited
    49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.1018Inherited
    48592,54849
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 0.1018Inherited
    57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.2831Inherited
    52490,55307
  • 52490 - Tubulin nucleotide-binding domain-like
  • 55307 - Tubulin C-terminal domain-like
  • 0.9094Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    54585,52540,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    50692,54585,52540
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    74788,75632,46785
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0.00003172Direct
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.004342Inherited
    49313,49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.0128Inherited
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.02135Inherited
    48726,48726,49265
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.06081Inherited
    48592,54849,52029
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.1018Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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