SUPERFAMILY 1.75 HMM library and genome assignments server

Superfamily is undergoing a server migration - you are now browsing on the new server. Please contact us if you experience any problems.

Worm Phenotype (WP): sterile

(show info)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)

Shortest distance to current term (+ for parents, - for children) WP term [WP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + + 6:   Variant [WBPhenotype:0000886] <5>
+ + + + + 5:   physiology variant [WBPhenotype:0000519] <7>(494|573) (495|248|68)
+ + + + 4:   organ system physiology variant [WBPhenotype:0000575] <8>(446|531) (446|235|67)
+ + + 3:   reproductive system physiology variant [WBPhenotype:0000613] <4>(440|528) (441|233|67)
+ + 2:   fertility variant [WBPhenotype:0000145] <4>(438|527) (439|232|66)
+ 1:   fertility reduced [WBPhenotype:0001384] <3>(428|521) (429|230|66)
0:   sterile [WBPhenotype:0000688] <3>(362|463) (363|209|58)
- 1:   hermaphrodite sterile [WBPhenotype:0000694] <3>(355|453) (355|209|58)
- 1:   sterile progeny [WBPhenotype:0001037] <2>(87|132) (88|61|17)
- 1:   male sterile [WBPhenotype:0000692] <1>(0|1) (0|0|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain1Inherited
Hormone receptor domain1Inherited
Metal cation-transporting ATPase, ATP-binding domain N1Inherited
Spectrin repeat1Inherited
PLP-binding barrel1Inherited
Cytidine deaminase-like1Inherited
Galactose-binding domain-like1Inherited
Spermadhesin, CUB domain1Inherited
FAD/NAD-linked reductases, dimerisation (C-terminal) domain1Inherited
Acyl-CoA dehydrogenase NM domain-like1Inherited
Phospholipase D/nuclease1Inherited
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain1Inherited
Bacterial exopeptidase dimerisation domain1Inherited
Mitochondrial cytochrome c oxidase subunit VIc1Inherited
Carbohydrate phosphatase1Inherited
Pseudouridine synthase1Inherited
Oxysterol-binding protein-like1Inherited
CRAL/TRIO domain1Inherited
NTF2-like1Inherited
CO dehydrogenase molybdoprotein N-domain-like1Inherited
WWE domain1Inherited
SMR domain-like1Inherited
Acid phosphatase/Vanadium-dependent haloperoxidase1Inherited
t-snare proteins1Inherited
LDH C-terminal domain-like1Inherited
Acyl-CoA dehydrogenase C-terminal domain-like1Inherited
Ribulose-phoshate binding barrel1Inherited
Clc chloride channel1Inherited
PHM/PNGase F1Inherited
NagB/RpiA/CoA transferase-like1Inherited
Transcription factor IIA (TFIIA), alpha-helical domain1Inherited
RCC1/BLIP-II1Inherited
cAMP-binding domain-like1Inherited
Hairpin loop containing domain-like1Inherited
SPOC domain-like1Inherited
HIT/MYND zinc finger-like1Inherited
Osmotin, thaumatin-like protein1Inherited
MFPT repeat-like1Inherited
MgtE membrane domain-like1Inherited
BRCT domain1Inherited
Metallo-hydrolase/oxidoreductase1Inherited
Aminoacid dehydrogenase-like, N-terminal domain1Inherited
Nop domain1Inherited
14-3-3 protein1Inherited
Nucleoporin domain1Inherited
beta and beta-prime subunits of DNA dependent RNA-polymerase1Inherited
TIMP-like1Inherited
Annexin1Inherited
Supernatant protein factor (SPF), C-terminal domain1Inherited
E2F-DP heterodimerization region1Inherited
GYF domain1Inherited
FAD-linked oxidases, C-terminal domain1Inherited
CBD9-like1Inherited
Lipovitellin-phosvitin complex; beta-sheet shell regions1Inherited
Tim10-like1Inherited
F1F0 ATP synthase subunit C1Inherited
Apyrase1Inherited
Zinc beta-ribbon1Inherited
Actin depolymerizing proteins1Inherited
DBL homology domain (DH-domain)1Inherited
HD-domain/PDEase-like1Inherited
Pectin lyase-like1Inherited
Transducin (heterotrimeric G protein), gamma chain1Inherited
BAR/IMD domain-like1Inherited
PYP-like sensor domain (PAS domain)1Inherited
TGS-like1Inherited
Sec7 domain1Inherited
Ganglioside M2 (gm2) activator1Inherited
Nucleotide-diphospho-sugar transferases1Inherited
Acyl-CoA binding protein1Inherited
Rhomboid-like1Inherited
LysM domain1Inherited
Metallo-dependent phosphatases1Inherited
GAS2 domain-like1Inherited
Glycolipid transfer protein, GLTP1Inherited
Polo-box domain1Inherited
Intermediate filament protein, coiled coil region1Inherited
Guanido kinase N-terminal domain1Inherited
RNA-binding domain, RBD1Inherited
Translation proteins SH3-like domain1Inherited
Subdomain of clathrin and coatomer appendage domain1Inherited
Folate-binding domain1Inherited
Succinyl-CoA synthetase domains1Inherited
alpha-helical ferredoxin1Inherited
Restriction endonuclease-like1Inherited
PUA domain-like1Inherited
Metalloproteases ("zincins"), catalytic domain1Inherited
C2 domain (Calcium/lipid-binding domain, CaLB)1Inherited
Glutamine synthetase/guanido kinase1Inherited
Cadherin-like1Inherited
Invertebrate chitin-binding proteins1Inherited
Cyclophilin-like1Inherited
Purine and uridine phosphorylases1Inherited
PurM C-terminal domain-like1Inherited
GHMP Kinase, C-terminal domain1Inherited
TK C-terminal domain-like1Inherited
Leukotriene A4 hydrolase N-terminal domain1Inherited
N-terminal nucleophile aminohydrolases (Ntn hydrolases)1Inherited
NAD kinase/diacylglycerol kinase-like1Inherited
ValRS/IleRS/LeuRS editing domain1Inherited
KA1-like1Inherited
Bromodomain1Inherited
Ammonium transporter1Inherited
Purple acid phosphatase, N-terminal domain1Inherited
Ypt/Rab-GAP domain of gyp1p1Inherited
Regulator of G-protein signaling, RGS1Inherited
3-carboxy-cis,cis-mucoante lactonizing enzyme1Inherited
PAZ domain1Inherited
S-adenosylmethionine synthetase1Inherited
FAD-binding/transporter-associated domain-like1Inherited
Ribosomal protein S101Inherited
WW domain1Inherited
Alkaline phosphatase-like1Inherited
MIT domain1Inherited
DHS-like NAD/FAD-binding domain1Inherited
Complement control module/SCR domain1Inherited
DNase I-like1Inherited
Rap/Ran-GAP1Inherited
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit1Inherited
Proton glutamate symport protein1Inherited
R3H domain1Inherited
Sema domain1Inherited
Surp module (SWAP domain)1Inherited
PEBP-like1Inherited
PapD-like1Inherited
PRTase-like1Inherited
Carbon-nitrogen hydrolase1Inherited
HRDC-like1Inherited
BSD domain-like1Inherited
Cysteine-rich domain1Inherited
ALDH-like1Inherited
C-terminal domain of alpha and beta subunits of F1 ATP synthase1Inherited
Seven-hairpin glycosidases1Inherited
Hemopexin-like domain1Inherited
Integrin alpha N-terminal domain1Inherited
Plexin repeat1Inherited
SAICAR synthase-like1Inherited
RNI-like1Inherited
Ras GEF1Inherited
Tautomerase/MIF1Inherited
eIF4e-like1Inherited
Di-copper centre-containing domain1Inherited
Outer arm dynein light chain 11Inherited
FF domain1Inherited
PEP carboxykinase-like1Inherited
Cytochrome c1Inherited
Bet v1-like1Inherited
Skp1 dimerisation domain-like1Inherited
PLP-dependent transferases1Inherited
CalX-like1Inherited
Protease propeptides/inhibitors1Inherited
Periplasmic binding protein-like II1Inherited
Rudiment single hybrid motif1Inherited
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor1Inherited
Kix domain of CBP (creb binding protein)1Inherited
Nucleotidyltransferase1Inherited
VPS9 domain1Inherited
beta-lactamase/transpeptidase-like1Inherited
SMAD MH1 domain1Inherited
PK beta-barrel domain-like1Inherited
Glycosyl hydrolase domain1Inherited
Carboxypeptidase regulatory domain-like1Inherited
Ribonuclease PH domain 2-like1Inherited
Lysozyme-like1Inherited
Creatinase/aminopeptidase1Inherited
Multidrug efflux transporter AcrB transmembrane domain1Inherited
FtsH protease domain-like1Inherited
Creatinase/prolidase N-terminal domain1Inherited
Glutamine synthetase, N-terminal domain1Inherited
Hect, E3 ligase catalytic domain1Inherited
Second domain of FERM1Inherited
HMG-box1Inherited
Cation efflux protein transmembrane domain-like1Inherited
Mss4-like1Inherited
BolA-like1Inherited
PAP/OAS1 substrate-binding domain1Inherited
Sec63 N-terminal domain-like1Inherited
HSP90 C-terminal domain1Inherited
Adenine nucleotide alpha hydrolases-like1Inherited
Actin-crosslinking proteins1Inherited
Fibronectin type III1Inherited
SGNH hydrolase1Inherited
SAND domain-like1Inherited
Ribosomal protein L11Inherited
ARID-like1Inherited
Aromatic aminoacid monoxygenases, catalytic and oligomerization domains1Inherited
AraD/HMP-PK domain-like1Inherited
Troponin coil-coiled subunits1Inherited
Glycerol-3-phosphate (1)-acyltransferase1Inherited
CBS-domain pair1Inherited
Translational machinery components1Inherited
PIN domain-like1Inherited
6-phosphogluconate dehydrogenase C-terminal domain-like1Inherited
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase1Inherited
PR-1-like1Inherited
Diaminopimelate epimerase-like1Inherited
DNA clamp1Inherited
YbiA-like1Inherited
Blood coagulation inhibitor (disintegrin)1Inherited
Hedgehog/intein (Hint) domain1Inherited
PAP/Archaeal CCA-adding enzyme, C-terminal domain1Inherited
Hypothetical protein c14orf129, hspc2101Inherited
ABC transporter transmembrane region1Inherited
AN1-like Zinc finger1Inherited
Cupredoxins1Inherited
Composite domain of metallo-dependent hydrolases1Inherited
TAZ domain1Inherited
Lipovitellin-phosvitin complex, superhelical domain1Inherited
RUN domain-like1Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain1Inherited
ClpP/crotonase1Inherited
SAP domain1Inherited
LuxS/MPP-like metallohydrolase1Inherited
SpoIIaa-like1Inherited
Transducin (alpha subunit), insertion domain1Inherited
Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase)1Inherited
Nucleoside diphosphate kinase, NDK1Inherited
HCP-like1Inherited
Galactose oxidase, central domain1Inherited
Six-hairpin glycosidases1Inherited
Ribosomal protein L10-like1Inherited
Arginase/deacetylase1Inherited
Thioesterase/thiol ester dehydrase-isomerase1Inherited
FAD-dependent thiol oxidase1Inherited
Acid proteases1Inherited
ADC-like1Inherited
Calpain large subunit, middle domain (domain III)1Inherited
FAD-linked reductases, C-terminal domain1Inherited
L30e-like1Inherited
Nucleotide cyclase1Inherited
Clathrin adaptor appendage domain1Inherited
CRAL/TRIO N-terminal domain1Inherited
Caspase-like1Inherited
Cysteine-rich DNA binding domain, (DM domain)1Inherited
Ribokinase-like1Inherited
Metallo-dependent hydrolases1Inherited
Epsilon subunit of mitochondrial F1F0-ATP synthase1Inherited
Myosin rod fragments1Inherited
HLH, helix-loop-helix DNA-binding domain1Inherited
Elafin-like1Inherited
Cation efflux protein cytoplasmic domain-like1Inherited
Integrin domains1Inherited
Periplasmic binding protein-like I1Inherited
SCP-like1Inherited
The spindle assembly checkpoint protein mad21Inherited
Calcium ATPase, transduction domain A1Inherited
B-box zinc-binding domain1Inherited
RuvA domain 2-like1Inherited
Chitinase insertion domain1Inherited
Cystatin/monellin1Inherited
PEP carboxykinase N-terminal domain1Inherited
Cytochrome b5-like heme/steroid binding domain1Inherited
Serine protease inhibitors1Inherited
Heme-dependent catalase-like1Inherited
Immunoglobulin1Inherited
DPP6 N-terminal domain-like1Inherited
Tricorn protease domain 21Inherited
Transcription factor IIA (TFIIA), beta-barrel domain1Inherited
Galactose mutarotase-like1Inherited
Activating enzymes of the ubiquitin-like proteins1Inherited
Thyroglobulin type-1 domain1Inherited
NHL repeat1Inherited
Serpins1Inherited
Cdc48 domain 2-like1Inherited
PX domain1Inherited
Phosphoenolpyruvate/pyruvate domain1Inherited
Calcium ATPase, transmembrane domain M1Inherited
Amidase signature (AS) enzymes1Inherited
dsRNA-binding domain-like1Inherited
Heme-dependent peroxidases1Inherited
RmlC-like cupins1Inherited
Phospholipase A2, PLA21Inherited
SWIB/MDM2 domain1Inherited
RBP11-like subunits of RNA polymerase1Inherited
ADP-ribosylation1Inherited
MOSC N-terminal domain-like1Inherited
BEACH domain1Inherited
SET domain1Inherited
FMN-linked oxidoreductases1Inherited
Cu,Zn superoxide dismutase-like1Inherited
Nudix1Inherited
Mob1/phocein1Inherited
Phosphoglycerate mutase-like1Inherited
EF-G C-terminal domain-like1Inherited
PP2C-like1Inherited
Small-conductance potassium channel1Inherited
alpha/beta knot1Inherited
GAT-like domain1Inherited
Aldolase1Inherited
Riboflavin synthase domain-like1Inherited
SMAD/FHA domain1Inherited
Rhodanese/Cell cycle control phosphatase1Inherited
Formate/glycerate dehydrogenase catalytic domain-like1Inherited
Glycoside hydrolase/deacetylase1Inherited
LEM domain1Inherited
Kringle-like1Inherited
MIR domain1Inherited
Kelch motif1Inherited
Flavoproteins1Inherited
BPTI-like1Inherited
lambda repressor-like DNA-binding domains1Inherited
DEATH domain1Inherited
Ricin B-like lectins1Inherited
ArfGap/RecO-like zinc finger1Inherited
p53-like transcription factors1Inherited
Lesion bypass DNA polymerase (Y-family), little finger domain1Inherited
Tubby C-terminal domain-like1Inherited
Carbonic anhydrase1Inherited
Domain of poly(ADP-ribose) polymerase1Inherited
Isocitrate/Isopropylmalate dehydrogenase-like1Inherited
Mitochondrial carrier1Inherited
Inhibitor of apoptosis (IAP) repeat1Inherited
SH2 domain1Inherited
Multidrug resistance efflux transporter EmrE1Inherited
Fibrinogen C-terminal domain-like1Inherited
Families 57/38 glycoside transferase middle domain1Inherited
Ran binding protein zinc finger-like1Inherited
Radical SAM enzymes1Inherited
Chromo domain-like1Inherited
Putative DNA-binding domain1Inherited
Phoshotransferase/anion transport protein1Inherited
Calcium-dependent phosphotriesterase1Inherited
PLC-like phosphodiesterases1Inherited
SNF-like1Inherited
Sec1/munc18-like (SM) proteins1Inherited
NAD(P)-linked oxidoreductase1Inherited
Alpha-L RNA-binding motif1Inherited
Subtilisin-like1Inherited
Doublecortin (DC)1Inherited
Pepsin inhibitor-31Inherited
CO dehydrogenase ISP C-domain like1Inherited
PABC (PABP) domain1Inherited
Ribosomal protein S181Inherited
SIS domain1Inherited
2Fe-2S ferredoxin-like1Inherited
eIF1-like1Inherited
Profilin (actin-binding protein)1Inherited
Pentein1Inherited
Ankyrin repeat1Inherited
Nucleotide-binding domain1Inherited
Molybdenum cofactor-binding domain1Inherited
Lipocalins1Inherited
Terpenoid cyclases/Protein prenyltransferases1Inherited
DNA repair protein MutS, domain III1Inherited
Molybdenum cofactor biosynthesis proteins1Inherited
Aquaporin-like1Inherited
N-terminal domain of alpha and beta subunits of F1 ATP synthase1Inherited
L-aspartase-like1Inherited
alpha-catenin/vinculin-like1Inherited
EB1 dimerisation domain-like1Inherited
Ferritin-like1Inherited
PreATP-grasp domain1Inherited
Aminomethyltransferase beta-barrel domain1Inherited
PGBD-like1Inherited
ISP domain1Inherited
5' to 3' exonuclease, C-terminal subdomain1Inherited
PurM N-terminal domain-like1Inherited
Acyl-CoA N-acyltransferases (Nat)1Inherited
Tudor/PWWP/MBT1Inherited
Cystine-knot cytokines1Inherited
HIT-like1Inherited
WGR domain-like1Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Clathrin coat assembly domain1Inherited
Oxysterol-binding protein1Inherited
HMG-box1Inherited
Ribonuclease PH domain 2-like1Inherited
Peptidylglycine alpha-hydroxylating monooxygenase, PHM1Inherited
POU-specific domain1Inherited
Translation initiation factor eIF4e1Inherited
Hydantoinase (dihydropyrimidinase)1Inherited
RIO1-like kinases1Inherited
YihX-like1Inherited
WWE domain1Inherited
AAT-like1Inherited
Methionine aminopeptidase, insert domain1Inherited
Chitinase insertion domain1Inherited
Small-conductance potassium channel1Inherited
6-phosphogluconate dehydrogenase-like, N-terminal domain1Inherited
H-NOX domain1Inherited
Apyrase1Inherited
Epsilon subunit of mitochondrial F1F0-ATP synthase1Inherited
PurM C-terminal domain-like1Inherited
Zf-UBP1Inherited
Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta1Inherited
Profilin (actin-binding protein)1Inherited
LIM domain1Inherited
Acireductone dioxygenase1Inherited
CalX-beta domain1Inherited
4HBT-like1Inherited
28-residue LRR1Inherited
PEP carboxykinase N-terminal domain1Inherited
Doublecortin (DC)1Inherited
RecA protein-like (ATPase-domain)1Inherited
Supernatant protein factor (SPF), C-terminal domain1Inherited
Osmotin, thaumatin-like protein1Inherited
Translational machinery components1Inherited
GHMP Kinase, N-terminal domain1Inherited
Kix domain of CBP (creb binding protein)1Inherited
cAMP-binding domain1Inherited
Cell cycle transcription factor e2f-dp1Inherited
Protein kinases, catalytic subunit1Inherited
GAS2 domain1Inherited
COMT-like1Inherited
SWIRM domain1Inherited
Glutamine synthetase catalytic domain1Inherited
PDEase1Inherited
Troponin I1Inherited
Acyl-CoA thioesterase1Inherited
MFPT repeat1Inherited
Arylsulfatase1Inherited
BEACH domain1Inherited
BC C-terminal domain-like1Inherited
LysM domain1Inherited
DPP6 catalytic domain-like1Inherited
Transducin (alpha subunit), insertion domain1Inherited
ValRS/IleRS/LeuRS editing domain1Inherited
Protein prenyltransferases1Inherited
BC N-terminal domain-like1Inherited
Ganglioside M2 (gm2) activator1Inherited
UBX domain1Inherited
acyl-CoA oxidase C-terminal domains1Inherited
Ribosomal protein L11Inherited
Sir2 family of transcriptional regulators1Inherited
PR-1-like1Inherited
Neurolysin-like1Inherited
F1F0 ATP synthase subunit C1Inherited
Lipovitellin-phosvitin complex; beta-sheet shell regions1Inherited
Subtilases1Inherited
Poly(ADP-ribose) polymerase, C-terminal domain1Inherited
Guanido kinase catalytic domain1Inherited
BolA-like1Inherited
beta-glycanases1Inherited
Poly(A) polymerase, PAP, C-terminal domain1Inherited
Eps15 homology domain (EH domain)1Inherited
Acylamino-acid-releasing enzyme, C-terminal donain1Inherited
Transducin (heterotrimeric G protein), gamma chain1Inherited
Third domain of FERM1Inherited
NLI interacting factor-like phosphatase1Inherited
Pseudouridine synthase I TruA1Inherited
Purple acid phosphatase-like1Inherited
Thyroglobulin type-1 domain1Inherited
Double-stranded RNA-binding domain (dsRBD)1Inherited
SMAD MH1 domain1Inherited
Sterol carrier protein, SCP1Inherited
Amidase signature (AS) enzymes1Inherited
AraD-like aldolase/epimerase1Inherited
Bacterial dinuclear zinc exopeptidases1Inherited
MIF-related1Inherited
Cell cycle control phosphatase, catalytic domain1Inherited
Smr domain1Inherited
Guanido kinase N-terminal domain1Inherited
Hemocyanin middle domain1Inherited
HLH, helix-loop-helix DNA-binding domain1Inherited
Gastric lipase1Inherited
Laminin-type module1Inherited
Astacin1Inherited
Quinoprotein alcohol dehydrogenase-like1Inherited
Inositol polyphosphate kinase (IPK)1Inherited
GAPDH-like1Inherited
PhyH-like1Inherited
PaaI/YdiI-like1Inherited
Lesion bypass DNA polymerase (Y-family), little finger domain1Inherited
14-3-3 protein1Inherited
Hsp90 middle domain1Inherited
Tetramerization domain of potassium channels1Inherited
Ribosomal protein L18 and S111Inherited
Choline/Carnitine O-acyltransferase1Inherited
t-snare proteins1Inherited
Phosphatidylethanolamine binding protein1Inherited
Rhomboid-like1Inherited
ALDH-like1Inherited
Heat shock protein 90, HSP90, N-terminal domain1Inherited
Medium chain acyl-CoA dehydrogenase-like, C-terminal domain1Inherited
Nop domain1Inherited
Succinyl-CoA synthetase domains1Inherited
Bromodomain1Inherited
FAD/NAD-linked reductases, dimerisation (C-terminal) domain1Inherited
Choline kinase1Inherited
HEAT repeat1Inherited
alpha-mannosidase, domain 21Inherited
Laminin G-like module1Inherited
DEP domain1Inherited
Aromatic aminoacid monoxygenases, catalytic and oligomerization domains1Inherited
TatD Mg-dependent DNase-like1Inherited
Ribokinase-like1Inherited
Cdc48 N-terminal domain-like1Inherited
BAR domain1Inherited
Adenosine/AMP deaminase1Inherited
D-aminoacid oxidase, N-terminal domain1Inherited
Spermadhesin, CUB domain1Inherited
Neutral endopeptidase (neprilysin)1Inherited
EF-G/eEF-2 domains III and V1Inherited
Cystathionine synthase-like1Inherited
BSD domain1Inherited
Glycogenin1Inherited
RNA editing terminal uridyl transferase 2, RET2, domain 21Inherited
Ngr ectodomain-like1Inherited
Matrix metalloproteases, catalytic domain1Inherited
Inhibitor of apoptosis (IAP) repeat1Inherited
Gelsolin-like1Inherited
Cytochrome b51Inherited
Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain1Inherited
Calcium ATPase, transduction domain A1Inherited
L-aminoacid/polyamine oxidase1Inherited
Glycerol-3-phosphate transporter1Inherited
Reprolysin-like1Inherited
NHL repeat1Inherited
Hedgehog C-terminal (Hog) autoprocessing domain1Inherited
Second domain of FERM1Inherited
Hydantoinase (dihydropyrimidinase), catalytic domain1Inherited
C-terminal domain of alpha and beta subunits of F1 ATP synthase1Inherited
F-box domain1Inherited
Formate/glycerate dehydrogenases, NAD-domain1Inherited
Phoshoinositide 3-kinase (PI3K) helical domain1Inherited
Sec7 domain1Inherited
L-arabinose binding protein-like1Inherited
IF2B-like1Inherited
FHA domain1Inherited
PX domain1Inherited
Aminomethyltransferase beta-barrel domain1Inherited
Plexin repeat1Inherited
AN1-like Zinc finger1Inherited
Calpain large subunit, catalytic domain (domain II)1Inherited
5' to 3' exonuclease, C-terminal subdomain1Inherited
Calcium ATPase, transmembrane domain M1Inherited
Fibronectin type III1Inherited
FAD-dependent thiol oxidase1Inherited
RhoGDI-like1Inherited
Regulator of chromosome condensation RCC11Inherited
Autophagin-like1Inherited
Fungal lipases1Inherited
Internalin LRR domain1Inherited
Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains1Inherited
NADPH-cytochrome p450 reductase FAD-binding domain-like1Inherited
Cdc48 domain 2-like1Inherited
Catalytic, N-terminal domain of histone methyltransferase Dot1l1Inherited
Galectin (animal S-lectin)1Inherited
Ribonucleotide reductase-like1Inherited
HSP201Inherited
Domain of poly(ADP-ribose) polymerase1Inherited
Tetraspanin1Inherited
N-terminal domain of alpha and beta subunits of F1 ATP synthase1Inherited
PDI-like1Inherited
Ubiquitin carboxyl-terminal hydrolase UCH-L1Inherited
Histone deacetylase, HDAC1Inherited
Amylase, catalytic domain1Inherited
E2F dimerization segment1Inherited
Erythroid transcription factor GATA-11Inherited
NTF2-like1Inherited
Ran binding protein zinc finger-like1Inherited
PurM N-terminal domain-like1Inherited
PP2C-like1Inherited
Polo-box duplicated region1Inherited
beta 1,4 galactosyltransferase (b4GalT1)1Inherited
Phoshatidylinositol transfer protein, PITP1Inherited
Sec63 C-terminal domain-like1Inherited
YbiA-like1Inherited
Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase)1Inherited
Clc chloride channel1Inherited
AlkB-like1Inherited
DNA repair protein MutS, domain III1Inherited
Serine carboxypeptidase-like1Inherited
NagD-like1Inherited
Acetylcholinesterase-like1Inherited
HD domain1Inherited
Surp module (SWAP domain)1Inherited
Cytidylyltransferase1Inherited
Cysteine-rich DNA binding domain, (DM domain)1Inherited
Bacterial lipase1Inherited
SNF-like1Inherited
Integrin domains1Inherited
RNA-polymerase beta-prime1Inherited
CRAL/TRIO N-terminal domain1Inherited
Skp1 dimerisation domain-like1Inherited
SAP domain1Inherited
Cadherin1Inherited
STAR domain1Inherited
Neurotransmitter-gated ion-channel transmembrane pore1Inherited
Class II glutamine amidotransferases1Inherited
HSP90 C-terminal domain1Inherited
Epoxide hydrolase1Inherited
Tim10/DDP1Inherited
Group II chaperonin (CCT, TRIC), intermediate domain1Inherited
Proteasome subunits1Inherited
Blood coagulation inhibitor (disintegrin)1Inherited
CBS-domain pair1Inherited
Ras GEF1Inherited
PEP carboxykinase C-terminal domain1Inherited
Kinase associated domain 1, KA11Inherited
Multidomain sulfurtransferase (rhodanese)1Inherited
WW domain1Inherited
Transcription factor IIA (TFIIA), alpha-helical domain1Inherited
Poly(A) polymerase, PAP, N-terminal domain1Inherited
T-box1Inherited
Myosin rod fragments1Inherited
2Fe-2S ferredoxin domains from multidomain proteins1Inherited
Ribosomal protein S101Inherited
Ribosomal protein S181Inherited
RUN domain1Inherited
Class I aldolase1Inherited
Myeloperoxidase-like1Inherited
Rv2717c-like1Inherited
Ypt/Rab-GAP domain of gyp1p1Inherited
5' to 3' exonuclease catalytic domain1Inherited
Heme-dependent catalases1Inherited
Anticodon-binding domain1Inherited
Leukotriene A4 hydrolase N-terminal domain1Inherited
Aquaporin-like1Inherited
Ribonuclease PH domain 1-like1Inherited
Mitochondrial carrier1Inherited
XPF/Rad1/Mus81 nuclease1Inherited
Ras-binding domain, RBD1Inherited
Bactericidal permeability-increasing protein, BPI1Inherited
Hect, E3 ligase catalytic domain1Inherited
Dimeric isocitrate & isopropylmalate dehydrogenases1Inherited
LacY-like proton/sugar symporter1Inherited
Small Kunitz-type inhibitors & BPTI-like toxins1Inherited
YicI catalytic domain-like1Inherited
Proton glutamate symport protein1Inherited
Creatinase/aminopeptidase1Inherited
Purine and uridine phosphorylases1Inherited
Phosphate binding protein-like1Inherited
Hermes transposase-like1Inherited
Sm motif of small nuclear ribonucleoproteins, SNRNP1Inherited
Carbonic anhydrase1Inherited
Gamma-glutamyltranspeptidase-like1Inherited
Lipovitellin-phosvitin complex, superhelical domain1Inherited
Extended PAW domain1Inherited
Hexokinase1Inherited
N-acetylglucosaminyltransferase I1Inherited
Proprotein convertase P-domain1Inherited
Annexin1Inherited
CoA transferase alpha subunit-like1Inherited
Adenain-like1Inherited
Pyk2-associated protein beta ARF-GAP domain1Inherited
SWIB/MDM2 domain1Inherited
Hypothetical protein c14orf129, hspc2101Inherited
LDH N-terminal domain-like1Inherited
beta-CASP RNA-metabolising hydrolases1Inherited
Aldo-keto reductases (NADP)1Inherited
First domain of FERM1Inherited
NOL1/NOP2/sun1Inherited
SH2 domain1Inherited
WGR domain1Inherited
Higher-molecular-weight phosphotyrosine protein phosphatases1Inherited
Calpain large subunit, middle domain (domain III)1Inherited
1,3-glucuronyltransferase1Inherited
Glutaminase1Inherited
Biotin dependent carboxylase carboxyltransferase domain1Inherited
Ribonuclease H1Inherited
Kelch motif1Inherited
Phoshoinositide 3-kinase (PI3K), catalytic domain1Inherited
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit1Inherited
I set domains1Inherited
FCH domain1Inherited
L domain1Inherited
Reductases1Inherited
Serum paraoxonase/arylesterase 1, PON11Inherited
Elongation factors1Inherited
Aminomethyltransferase folate-binding domain1Inherited
Arylamine N-methyltransferase1Inherited
Glycerol kinase1Inherited
ets domain1Inherited
Pancreatic carboxypeptidase, activation domain1Inherited
NADPH-cytochrome p450 reductase-like1Inherited
Mob1/phocein1Inherited
Cofilin-like1Inherited
Patatin1Inherited
Meta-cation ATPase, catalytic domain P1Inherited
SMAD domain1Inherited
Fibrinogen C-terminal domain-like1Inherited
Linker histone H1/H51Inherited
Chromo domain1Inherited
MPP-like1Inherited
Rap/Ran-GAP1Inherited
C-type lectin domain1Inherited
RNA-polymerase beta1Inherited
Protein serine/threonine phosphatase1Inherited
Lactate & malate dehydrogenases, C-terminal domain1Inherited
D-aminoacid oxidase-like1Inherited
Adenylyl and guanylyl cyclase catalytic domain1Inherited
Family 19 glycosidase1Inherited
PAZ domain1Inherited
Crotonase-like1Inherited
Sec63 N-terminal domain1Inherited
FAD/NAD-linked reductases, N-terminal and central domains1Inherited
EF-hand modules in multidomain proteins1Inherited
FMN-linked oxidoreductases1Inherited
Polypeptide N-acetylgalactosaminyltransferase 1, N-terminal domain1Inherited
Purple acid phosphatase, N-terminal domain1Inherited
Multidrug efflux transporter AcrB transmembrane domain1Inherited
N-type ATP pyrophosphatases1Inherited
Sema domain1Inherited
Synaptotagmin-like (S variant)1Inherited
AMPK-beta glycogen binding domain-like1Inherited
GABA-aminotransferase-like1Inherited
Ankyrin repeat1Inherited
Arginine methyltransferase1Inherited
DBL homology domain (DH-domain)1Inherited
Acyl-CoA binding protein1Inherited
LEM domain1Inherited
MIT domain1Inherited
N-acetyl transferase, NAT1Inherited
Aminoacid dehydrogenase-like, C-terminal domain1Inherited
FAD-linked reductases, N-terminal domain1Inherited
Intermediate filament protein, coiled coil region1Inherited
Poly(A) polymerase, PAP, middle domain1Inherited
Leukotriene A4 hydrolase catalytic domain1Inherited
eIF1-like1Inherited
Pancreatic carboxypeptidases1Inherited
SAND domain1Inherited
Ferredoxin reductase FAD-binding domain-like1Inherited
p120GAP domain-like1Inherited
Lesion bypass DNA polymerase (Y-family), catalytic domain1Inherited
TAZ domain1Inherited
S-adenosylmethionine synthetase1Inherited
Hormone receptor domain1Inherited
MIR domain1Inherited
Phosphotyrosine-binding domain (PTB)1Inherited
Complement control module/SCR domain1Inherited
HAT/Suf repeat1Inherited
Inositol polyphosphate 5-phosphatase (IPP5)1Inherited
Classic zinc finger, C2H21Inherited
Glycolipid transfer protein, GLTP1Inherited
Type II chitinase1Inherited
beta-Lactamase/D-ala carboxypeptidase1Inherited
HCDH C-domain-like1Inherited
SAM (sterile alpha motif) domain1Inherited
Myotubularin-like phosphatases1Inherited
Hemopexin-like domain1Inherited
ZZ domain1Inherited
CO dehydrogenase molybdoprotein N-domain-like1Inherited
Cyclophilin (peptidylprolyl isomerase)1Inherited
PABC (PABP) domain1Inherited
Mammalian PLC1Inherited
CRAL/TRIO domain1Inherited
GYF domain1Inherited
Transcriptional factor domain1Inherited
Clathrin adaptor core protein1Inherited
La domain1Inherited
Canonical RBD1Inherited
Ubiquitin activating enzymes (UBA)1Inherited
alpha-catenin/vinculin1Inherited
Papain-like1Inherited
Carboxypeptidase regulatory domain1Inherited
DEATH domain, DD1Inherited
Band 7/SPFH domain1Inherited
CO dehydrogenase ISP C-domain like1Inherited
Serpins1Inherited
Glycerophosphoryl diester phosphodiesterase1Inherited
Sec1/munc18-like (SM) proteins1Inherited
FF domain1Inherited
Nucleoside diphosphate kinase, NDK1Inherited
Cation efflux protein cytoplasmic domain-like1Inherited
Glutamine synthetase, N-terminal domain1Inherited
CoA-binding domain1Inherited
Molybdenum cofactor-binding domain1Inherited
alpha-mannosidase, C-terminal domain1Inherited
Transforming growth factor (TGF)-beta1Inherited
MSP-like1Inherited
PLC-like (P variant)1Inherited
PhzC/PhzF-like1Inherited
Metal cation-transporting ATPase, ATP-binding domain N1Inherited
BC ATP-binding domain-like1Inherited
RNA methyltransferase FtsJ1Inherited
Transcription factor IIA (TFIIA), beta-barrel domain1Inherited
Integrin A (or I) domain1Inherited
TBP-associated factors, TAFs1Inherited
alpha-mannosidase1Inherited
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor1Inherited
Cation efflux protein transmembrane domain-like1Inherited
UDP-glucose pyrophosphorylase1Inherited
FtsH protease domain-like1Inherited
Fatty acid binding protein-like1Inherited
U-box1Inherited
MOSC N-terminal domain-like1Inherited
Regulator of G-protein signaling, RGS1Inherited
Pepsin inhibitor-31Inherited
Pyridoxal-dependent decarboxylase1Inherited
Spectrin repeat1Inherited
Ephrin ectodomain1Inherited
Histidine acid phosphatase1Inherited
MIF4G domain-like1Inherited
Deoxycytidylate deaminase-like1Inherited
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain1Inherited
MutT-like1Inherited
Elafin-like1Inherited
Filamin repeat (rod domain)1Inherited
Inositol monophosphatase/fructose-1,6-bisphosphatase-like1Inherited
Tandem AAA-ATPase domain1Inherited
Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain1Inherited
Histone lysine methyltransferases1Inherited
Trehalase-like1Inherited
L30e/L7ae ribosomal proteins1Inherited
Ammonium transporter1Inherited
Protein kinase cysteine-rich domain (cys2, phorbol-binding domain)1Inherited
Cu,Zn superoxide dismutase-like1Inherited
Phosphoribosyltransferases (PRTases)1Inherited
ABC transporter transmembrane region1Inherited
Tudor domain1Inherited
Ricin B-like1Inherited
ATP-dependent protease Lon (La), catalytic domain1Inherited
UDPGT-like1Inherited
EB1 dimerisation domain-like1Inherited
Dual specificity phosphatase-like1Inherited
B-box zinc-binding domain1Inherited
Cytoplasmic domain of inward rectifier potassium channel1Inherited
alpha-Amylases, C-terminal beta-sheet domain1Inherited
Carboxylesterase1Inherited
Class I alpha-1;2-mannosidase, catalytic domain1Inherited
Bacterial exopeptidase dimerisation domain1Inherited
ATI-like1Inherited
CUT domain1Inherited
Paired domain1Inherited
DPP6 N-terminal domain-like1Inherited
CO dehydrogenase flavoprotein N-terminal domain-like1Inherited
Caspase catalytic domain1Inherited
UBA domain1Inherited
PUA domain1Inherited
acyl-CoA oxidase N-terminal domains1Inherited
ARID domain1Inherited
Mo25 protein1Inherited
Arfaptin, Rac-binding fragment1Inherited
Pepsin-like1Inherited
Pleckstrin-homology domain (PH domain)1Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
Plot tree as:   Download Newick format tree:
(show help)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
SNF-like1Inherited
Lipocalins1Inherited
Rhomboid-like1Inherited
Lipovitellin-phosvitin complex, superhelical domain1Inherited
Outer arm dynein light chain 11Inherited
Sema domain1Inherited
DNA repair protein MutS, domain III1Inherited
Cupredoxins1Inherited
Polo-box domain1Inherited
Kringle-like1Inherited
Mitochondrial carrier1Inherited
NAD(P)-linked oxidoreductase1Inherited
ABC transporter transmembrane region1Inherited
MFPT repeat-like1Inherited
ADP-ribosylation1Inherited
Purple acid phosphatase, N-terminal domain1Inherited
Cu,Zn superoxide dismutase-like1Inherited
beta-lactamase/transpeptidase-like1Inherited
Metallo-dependent phosphatases1Inherited
ArfGap/RecO-like zinc finger1Inherited
Calcium ATPase, transduction domain A1Inherited
Glycerol-3-phosphate (1)-acyltransferase1Inherited
Restriction endonuclease-like1Inherited
eIF4e-like1Inherited
DPP6 N-terminal domain-like1Inherited
CRAL/TRIO domain1Inherited
Surp module (SWAP domain)1Inherited
Pentein1Inherited
Subtilisin-like1Inherited
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain1Inherited
MIR domain1Inherited
Seven-hairpin glycosidases1Inherited
Creatinase/aminopeptidase1Inherited
Ribosomal protein L11Inherited
RBP11-like subunits of RNA polymerase1Inherited
Nudix1Inherited
Cystine-knot cytokines1Inherited
Mitochondrial cytochrome c oxidase subunit VIc1Inherited
B-box zinc-binding domain1Inherited
p53-like transcription factors1Inherited
PABC (PABP) domain1Inherited
Invertebrate chitin-binding proteins1Inherited
Cadherin-like1Inherited
Chitinase insertion domain1Inherited
EB1 dimerisation domain-like1Inherited
dsRNA-binding domain-like1Inherited
Profilin (actin-binding protein)1Inherited
Multidrug resistance efflux transporter EmrE1Inherited
SWIB/MDM2 domain1Inherited
Acid phosphatase/Vanadium-dependent haloperoxidase1Inherited
LysM domain1Inherited
PAP/OAS1 substrate-binding domain1Inherited
SAP domain1Inherited
NagB/RpiA/CoA transferase-like1Inherited
CBD9-like1Inherited
HCP-like1Inherited
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase1Inherited
Pseudouridine synthase1Inherited
Osmotin, thaumatin-like protein1Inherited
FAD-dependent thiol oxidase1Inherited
alpha/beta knot1Inherited
ValRS/IleRS/LeuRS editing domain1Inherited
Terpenoid cyclases/Protein prenyltransferases1Inherited
Skp1 dimerisation domain-like1Inherited
RNI-like1Inherited
Adenine nucleotide alpha hydrolases-like1Inherited
Cdc48 domain 2-like1Inherited
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor1Inherited
Pectin lyase-like1Inherited
LEM domain1Inherited
Activating enzymes of the ubiquitin-like proteins1Inherited
Heme-dependent peroxidases1Inherited
Kix domain of CBP (creb binding protein)1Inherited
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit1Inherited
Lesion bypass DNA polymerase (Y-family), little finger domain1Inherited
Sec1/munc18-like (SM) proteins1Inherited
MOSC N-terminal domain-like1Inherited
Aldolase1Inherited
Small-conductance potassium channel1Inherited
Serine protease inhibitors1Inherited
6-phosphogluconate dehydrogenase C-terminal domain-like1Inherited
lambda repressor-like DNA-binding domains1Inherited
GAT-like domain1Inherited
ClpP/crotonase1Inherited
E2F-DP heterodimerization region1Inherited
Hect, E3 ligase catalytic domain1Inherited
EF-G C-terminal domain-like1Inherited
3-carboxy-cis,cis-mucoante lactonizing enzyme1Inherited
Ran binding protein zinc finger-like1Inherited
Phosphoenolpyruvate/pyruvate domain1Inherited
Rap/Ran-GAP1Inherited
Nucleotide cyclase1Inherited
SpoIIaa-like1Inherited
Transducin (heterotrimeric G protein), gamma chain1Inherited
Tudor/PWWP/MBT1Inherited
PRTase-like1Inherited
MgtE membrane domain-like1Inherited
PX domain1Inherited
RCC1/BLIP-II1Inherited
FtsH protease domain-like1Inherited
PurM N-terminal domain-like1Inherited
Chromo domain-like1Inherited
Glutamine synthetase/guanido kinase1Inherited
Galactose-binding domain-like1Inherited
Tubby C-terminal domain-like1Inherited
Annexin1Inherited
N-terminal nucleophile aminohydrolases (Ntn hydrolases)1Inherited
WW domain1Inherited
Epsilon subunit of mitochondrial F1F0-ATP synthase1Inherited
KA1-like1Inherited
TK C-terminal domain-like1Inherited
PR-1-like1Inherited
R3H domain1Inherited
Protein kinase-like (PK-like)1Inherited
Aromatic aminoacid monoxygenases, catalytic and oligomerization domains1Inherited
Translational machinery components1Inherited
NTF2-like1Inherited
DNase I-like1Inherited
Aminomethyltransferase beta-barrel domain1Inherited
Leukotriene A4 hydrolase N-terminal domain1Inherited
NAD kinase/diacylglycerol kinase-like1Inherited
2Fe-2S ferredoxin-like1Inherited
t-snare proteins1Inherited
BAR/IMD domain-like1Inherited
Glycosyl hydrolase domain1Inherited
CBS-domain pair1Inherited
PLP-binding barrel1Inherited
Metalloproteases ("zincins"), catalytic domain1Inherited
Creatinase/prolidase N-terminal domain1Inherited
Nucleoporin domain1Inherited
Aquaporin-like1Inherited
Galactose mutarotase-like1Inherited
Ras GEF1Inherited
LuxS/MPP-like metallohydrolase1Inherited
PK beta-barrel domain-like1Inherited
SAND domain-like1Inherited
Phosphoglycerate mutase-like1Inherited
Phospholipase A2, PLA21Inherited
Serpins1Inherited
SCP-like1Inherited
Ypt/Rab-GAP domain of gyp1p1Inherited
Spermadhesin, CUB domain1Inherited
CO dehydrogenase molybdoprotein N-domain-like1Inherited
Transcription factor IIA (TFIIA), beta-barrel domain1Inherited
ADC-like1Inherited
SGNH hydrolase1Inherited
BolA-like1Inherited
Multidrug efflux transporter AcrB transmembrane domain1Inherited
Translation proteins SH3-like domain1Inherited
Thyroglobulin type-1 domain1Inherited
Oxysterol-binding protein-like1Inherited
Metallo-hydrolase/oxidoreductase1Inherited
PIN domain-like1Inherited
Flavoproteins1Inherited
Acyl-CoA dehydrogenase C-terminal domain-like1Inherited
DBL homology domain (DH-domain)1Inherited
Proton glutamate symport protein1Inherited
Spectrin repeat1Inherited
Subdomain of clathrin and coatomer appendage domain1Inherited
Arginase/deacetylase1Inherited
TIMP-like1Inherited
Lipovitellin-phosvitin complex; beta-sheet shell regions1Inherited
Calpain large subunit, middle domain (domain III)1Inherited
Six-hairpin glycosidases1Inherited
eIF1-like1Inherited
FAD-binding/transporter-associated domain-like1Inherited
CRAL/TRIO N-terminal domain1Inherited
Ankyrin repeat1Inherited
Immunoglobulin1Inherited
Cysteine-rich domain1Inherited
14-3-3 protein1Inherited
Galactose oxidase, central domain1Inherited
Metallo-dependent hydrolases1Inherited
HD-domain/PDEase-like1Inherited
Cysteine-rich DNA binding domain, (DM domain)1Inherited
Clc chloride channel1Inherited
Fibrinogen C-terminal domain-like1Inherited
FAD/NAD-linked reductases, dimerisation (C-terminal) domain1Inherited
C-terminal domain of alpha and beta subunits of F1 ATP synthase1Inherited
Periplasmic binding protein-like II1Inherited
BRCT domain1Inherited
Intermediate filament protein, coiled coil region1Inherited
Domain of poly(ADP-ribose) polymerase1Inherited
Lysozyme-like1Inherited
Inhibitor of apoptosis (IAP) repeat1Inherited
Integrin domains1Inherited
FMN-linked oxidoreductases1Inherited
Ribosomal protein S181Inherited
Phospholipase D/nuclease1Inherited
SIS domain1Inherited
Composite domain of metallo-dependent hydrolases1Inherited
S-adenosylmethionine synthetase1Inherited
Purine and uridine phosphorylases1Inherited
SH2 domain1Inherited
PYP-like sensor domain (PAS domain)1Inherited
Acyl-CoA binding protein1Inherited
Kelch motif1Inherited
Second domain of FERM1Inherited
Ribokinase-like1Inherited
Fibronectin type III1Inherited
Sec63 N-terminal domain-like1Inherited
Cystatin/monellin1Inherited
SMR domain-like1Inherited
L30e-like1Inherited
PUA domain-like1Inherited
TAZ domain1Inherited
Nucleotide-diphospho-sugar transferases1Inherited
PapD-like1Inherited
Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase)1Inherited
Actin-crosslinking proteins1Inherited
Protease propeptides/inhibitors1Inherited
Phoshotransferase/anion transport protein1Inherited
Alkaline phosphatase-like1Inherited
NHL repeat1Inherited
Carbohydrate phosphatase1Inherited
GYF domain1Inherited
PEP carboxykinase-like1Inherited
Di-copper centre-containing domain1Inherited
Hairpin loop containing domain-like1Inherited
Calcium ATPase, transmembrane domain M1Inherited
Ribosomal protein S101Inherited
Folate-binding domain1Inherited
Ganglioside M2 (gm2) activator1Inherited
Ricin B-like lectins1Inherited
Tim10-like1Inherited
YbiA-like1Inherited
Clathrin adaptor appendage domain1Inherited
Ribosomal protein L10-like1Inherited
CalX-like1Inherited
Diaminopimelate epimerase-like1Inherited
cAMP-binding domain-like1Inherited
Carbonic anhydrase1Inherited
HMG-box1Inherited
Cyclophilin-like1Inherited
Ribulose-phoshate binding barrel1Inherited
AraD/HMP-PK domain-like1Inherited
SAICAR synthase-like1Inherited
FF domain1Inherited
Plexin repeat1Inherited
Putative DNA-binding domain1Inherited
Amidase signature (AS) enzymes1Inherited
Glycoside hydrolase/deacetylase1Inherited
F1F0 ATP synthase subunit C1Inherited
RmlC-like cupins1Inherited
BEACH domain1Inherited
alpha-catenin/vinculin-like1Inherited
Formate/glycerate dehydrogenase catalytic domain-like1Inherited
PEP carboxykinase N-terminal domain1Inherited
Hormone receptor domain1Inherited
Blood coagulation inhibitor (disintegrin)1Inherited
WWE domain1Inherited
RUN domain-like1Inherited
Cytidine deaminase-like1Inherited
Mss4-like1Inherited
Apyrase1Inherited
Hemopexin-like domain1Inherited
Acyl-CoA dehydrogenase NM domain-like1Inherited
alpha-helical ferredoxin1Inherited
Families 57/38 glycoside transferase middle domain1Inherited
Glycolipid transfer protein, GLTP1Inherited
BSD domain-like1Inherited
Elafin-like1Inherited
GHMP Kinase, C-terminal domain1Inherited
Nop domain1Inherited
Riboflavin synthase domain-like1Inherited
Zinc beta-ribbon1Inherited
Glutamine synthetase, N-terminal domain1Inherited
VPS9 domain1Inherited
Bet v1-like1Inherited
DNA clamp1Inherited
Cytochrome c1Inherited
Transducin (alpha subunit), insertion domain1Inherited
beta and beta-prime subunits of DNA dependent RNA-polymerase1Inherited
Ribonuclease PH domain 2-like1Inherited
CO dehydrogenase ISP C-domain like1Inherited
Carbon-nitrogen hydrolase1Inherited
Rudiment single hybrid motif1Inherited
Tricorn protease domain 21Inherited
SPOC domain-like1Inherited
DEATH domain1Inherited
Cytochrome b5-like heme/steroid binding domain1Inherited
Caspase-like1Inherited
ARID-like1Inherited
SMAD/FHA domain1Inherited
Rhodanese/Cell cycle control phosphatase1Inherited
Actin depolymerizing proteins1Inherited
Succinyl-CoA synthetase domains1Inherited
DHS-like NAD/FAD-binding domain1Inherited
Complement control module/SCR domain1Inherited
Molybdenum cofactor-binding domain1Inherited
SMAD MH1 domain1Inherited
Aminoacid dehydrogenase-like, N-terminal domain1Inherited
TGS-like1Inherited
Radical SAM enzymes1Inherited
Ammonium transporter1Inherited
Sec7 domain1Inherited
HRDC-like1Inherited
LDH C-terminal domain-like1Inherited
N-terminal domain of alpha and beta subunits of F1 ATP synthase1Inherited
PurM C-terminal domain-like1Inherited
Regulator of G-protein signaling, RGS1Inherited
Mob1/phocein1Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain1Inherited
PAZ domain1Inherited
Acyl-CoA N-acyltransferases (Nat)1Inherited
5' to 3' exonuclease, C-terminal subdomain1Inherited
Nucleoside diphosphate kinase, NDK1Inherited
BPTI-like1Inherited
PAP/Archaeal CCA-adding enzyme, C-terminal domain1Inherited
PP2C-like1Inherited
The spindle assembly checkpoint protein mad21Inherited
Alpha-L RNA-binding motif1Inherited
Nucleotide-binding domain1Inherited
RNA-binding domain, RBD1Inherited
AN1-like Zinc finger1Inherited
Acid proteases1Inherited
Thioesterase/thiol ester dehydrase-isomerase1Inherited
Isocitrate/Isopropylmalate dehydrogenase-like1Inherited
HLH, helix-loop-helix DNA-binding domain1Inherited
Pepsin inhibitor-31Inherited
PLC-like phosphodiesterases1Inherited
HIT-like1Inherited
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain1Inherited
Bromodomain1Inherited
Troponin coil-coiled subunits1Inherited
Integrin alpha N-terminal domain1Inherited
PGBD-like1Inherited
Tautomerase/MIF1Inherited
RuvA domain 2-like1Inherited
Periplasmic binding protein-like I1Inherited
Transcription factor IIA (TFIIA), alpha-helical domain1Inherited
Myosin rod fragments1Inherited
Supernatant protein factor (SPF), C-terminal domain1Inherited
HSP90 C-terminal domain1Inherited
Calcium-dependent phosphotriesterase1Inherited
PEBP-like1Inherited
Doublecortin (DC)1Inherited
PHM/PNGase F1Inherited
ALDH-like1Inherited
FAD-linked oxidases, C-terminal domain1Inherited
Hypothetical protein c14orf129, hspc2101Inherited
Cation efflux protein cytoplasmic domain-like1Inherited
FAD-linked reductases, C-terminal domain1Inherited
Hedgehog/intein (Hint) domain1Inherited
Metal cation-transporting ATPase, ATP-binding domain N1Inherited
PLP-dependent transferases1Inherited
Heme-dependent catalase-like1Inherited
Nucleotidyltransferase1Inherited
ISP domain1Inherited
Carboxypeptidase regulatory domain-like1Inherited
Ferritin-like1Inherited
HIT/MYND zinc finger-like1Inherited
C2 domain (Calcium/lipid-binding domain, CaLB)1Inherited
Cation efflux protein transmembrane domain-like1Inherited
L-aspartase-like1Inherited
GAS2 domain-like1Inherited
Molybdenum cofactor biosynthesis proteins1Inherited
Guanido kinase N-terminal domain1Inherited
PreATP-grasp domain1Inherited
MIT domain1Inherited
SET domain1Inherited
WGR domain-like1Inherited
Bacterial exopeptidase dimerisation domain1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
55486,57552
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 57552 - Blood coagulation inhibitor (disintegrin)
  • 1Inherited
    141673,50800
  • 141673 - MOSC N-terminal domain-like
  • 50800 - PK beta-barrel domain-like
  • 1Inherited
    90123,52540
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 1Inherited
    51206,51206
  • 51206 - cAMP-binding domain-like
  • 51206 - cAMP-binding domain-like
  • 1Inherited
    100950,100950
  • 100950 - NagB/RpiA/CoA transferase-like
  • 100950 - NagB/RpiA/CoA transferase-like
  • 1Inherited
    57889,48350
  • 57889 - Cysteine-rich domain
  • 48350 - GTPase activation domain, GAP
  • 1Inherited
    54897,53187
  • 54897 - Protease propeptides/inhibitors
  • 53187 - Zn-dependent exopeptidases
  • 1Inherited
    141739,141739
  • 141739 - MFPT repeat-like
  • 141739 - MFPT repeat-like
  • 1Inherited
    53187,55031
  • 53187 - Zn-dependent exopeptidases
  • 55031 - Bacterial exopeptidase dimerisation domain
  • 1Inherited
    141072,141072
  • 141072 - CalX-like
  • 141072 - CalX-like
  • 1Inherited
    57414,57414
  • 57414 - Hairpin loop containing domain-like
  • 57414 - Hairpin loop containing domain-like
  • 1Inherited
    63411,63411
  • 63411 - LuxS/MPP-like metallohydrolase
  • 63411 - LuxS/MPP-like metallohydrolase
  • 1Inherited
    57184,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 1Inherited
    81383,52047
  • 81383 - F-box domain
  • 52047 - RNI-like
  • 1Inherited
    54637,54637
  • 54637 - Thioesterase/thiol ester dehydrase-isomerase
  • 54637 - Thioesterase/thiol ester dehydrase-isomerase
  • 1Inherited
    57889,50729
  • 57889 - Cysteine-rich domain
  • 50729 - PH domain-like
  • 1Inherited
    55486,50923
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 1Inherited
    47220,47220
  • 47220 - alpha-catenin/vinculin-like
  • 47220 - alpha-catenin/vinculin-like
  • 1Inherited
    47741,56176
  • 47741 - CO dehydrogenase ISP C-domain like
  • 56176 - FAD-binding/transporter-associated domain-like
  • 1Inherited
    81631,55003
  • 81631 - PAP/OAS1 substrate-binding domain
  • 55003 - PAP/Archaeal CCA-adding enzyme, C-terminal domain
  • 1Inherited
    57756,50630
  • 57756 - Retrovirus zinc finger-like domains
  • 50630 - Acid proteases
  • 1Inherited
    53474,53474
  • 53474 - alpha/beta-Hydrolases
  • 53474 - alpha/beta-Hydrolases
  • 1Inherited
    46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 1Inherited
    48403,52151
  • 48403 - Ankyrin repeat
  • 52151 - FabD/lysophospholipase-like
  • 1Inherited
    52058,52058
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 1Inherited
    101690,53098
  • 101690 - PAZ domain
  • 53098 - Ribonuclease H-like
  • 1Inherited
    51695,49562
  • 51695 - PLC-like phosphodiesterases
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 1Inherited
    49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 1Inherited
    49854,49854
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 1Inherited
    53901,53901
  • 53901 - Thiolase-like
  • 53901 - Thiolase-like
  • 1Inherited
    55486,49854
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 49854 - Spermadhesin, CUB domain
  • 1Inherited
    48334,52540
  • 48334 - DNA repair protein MutS, domain III
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 1Inherited
    47895,52540
  • 47895 - Transducin (alpha subunit), insertion domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 1Inherited
    51971,54373
  • 51971 - Nucleotide-binding domain
  • 54373 - FAD-linked reductases, C-terminal domain
  • 1Inherited
    161111,160240
  • 161111 - Cation efflux protein transmembrane domain-like
  • 160240 - Cation efflux protein cytoplasmic domain-like
  • 1Inherited
    51735,56327
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 56327 - LDH C-terminal domain-like
  • 1Inherited
    51735,55347
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 55347 - Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain
  • 1Inherited
    63380,52343
  • 63380 - Riboflavin synthase domain-like
  • 52343 - Ferredoxin reductase-like, C-terminal NADP-linked domain
  • 1Inherited
    56601,48403
  • 56601 - beta-lactamase/transpeptidase-like
  • 48403 - Ankyrin repeat
  • 1Inherited
    56059,52210
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 52210 - Succinyl-CoA synthetase domains
  • 1Inherited
    54495,46934
  • 54495 - UBC-like
  • 46934 - UBA-like
  • 1Inherited
    50447,50465
  • 50447 - Translation proteins
  • 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
  • 1Inherited
    50692,54585
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 1Inherited
    48431,56968
  • 48431 - Lipovitellin-phosvitin complex, superhelical domain
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 1Inherited
    117281,117281
  • 117281 - Kelch motif
  • 117281 - Kelch motif
  • 1Inherited
    54001,49758
  • 54001 - Cysteine proteinases
  • 49758 - Calpain large subunit, middle domain (domain III)
  • 1Inherited
    56784,81665
  • 56784 - HAD-like
  • 81665 - Calcium ATPase, transmembrane domain M
  • 1Inherited
    47576,47576
  • 47576 - Calponin-homology domain, CH-domain
  • 47576 - Calponin-homology domain, CH-domain
  • 1Inherited
    57756,57756
  • 57756 - Retrovirus zinc finger-like domains
  • 57756 - Retrovirus zinc finger-like domains
  • 1Inherited
    48403,48403
  • 48403 - Ankyrin repeat
  • 48403 - Ankyrin repeat
  • 1Inherited
    48371,56112
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 1Inherited
    63737,55486
  • 63737 - Leukotriene A4 hydrolase N-terminal domain
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 1Inherited
    82615,82615
  • 82615 - Polo-box domain
  • 82615 - Polo-box domain
  • 1Inherited
    54160,54160
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 1Inherited
    53300,56436
  • 53300 - vWA-like
  • 56436 - C-type lectin-like
  • 1Inherited
    51045,51045
  • 51045 - WW domain
  • 51045 - WW domain
  • 1Inherited
    81301,81631
  • 81301 - Nucleotidyltransferase
  • 81631 - PAP/OAS1 substrate-binding domain
  • 1Inherited
    57863,48403
  • 57863 - ArfGap/RecO-like zinc finger
  • 48403 - Ankyrin repeat
  • 1Inherited
    52540,46785
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 46785 - "Winged helix" DNA-binding domain
  • 1Inherited
    50249,55681
  • 50249 - Nucleic acid-binding proteins
  • 55681 - Class II aaRS and biotin synthetases
  • 1Inherited
    57903,82199
  • 57903 - FYVE/PHD zinc finger
  • 82199 - SET domain
  • 1Inherited
    55326,56042
  • 55326 - PurM N-terminal domain-like
  • 56042 - PurM C-terminal domain-like
  • 1Inherited
    57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 1Inherited
    48726,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 1Inherited
    51735,50129
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 50129 - GroES-like
  • 1Inherited
    51905,54373
  • 51905 - FAD/NAD(P)-binding domain
  • 54373 - FAD-linked reductases, C-terminal domain
  • 1Inherited
    54695,81382
  • 54695 - POZ domain
  • 81382 - Skp1 dimerisation domain-like
  • 1Inherited
    64356,49447
  • 64356 - SNARE-like
  • 49447 - Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor
  • 1Inherited
    81324,53850
  • 81324 - Voltage-gated potassium channels
  • 53850 - Periplasmic binding protein-like II
  • 1Inherited
    56436,49854
  • 56436 - C-type lectin-like
  • 49854 - Spermadhesin, CUB domain
  • 1Inherited
    54665,56003
  • 54665 - CO dehydrogenase molybdoprotein N-domain-like
  • 56003 - Molybdenum cofactor-binding domain
  • 1Inherited
    52518,52922
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 52922 - TK C-terminal domain-like
  • 1Inherited
    52087,101576
  • 52087 - CRAL/TRIO domain
  • 101576 - Supernatant protein factor (SPF), C-terminal domain
  • 1Inherited
    82171,53474
  • 82171 - DPP6 N-terminal domain-like
  • 53474 - alpha/beta-Hydrolases
  • 1Inherited
    50729,56112
  • 50729 - PH domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 1Inherited
    52799,52799
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 1Inherited
    48403,52113
  • 48403 - Ankyrin repeat
  • 52113 - BRCT domain
  • 1Inherited
    56112,48371
  • 56112 - Protein kinase-like (PK-like)
  • 48371 - ARM repeat
  • 1Inherited
    53187,49464
  • 53187 - Zn-dependent exopeptidases
  • 49464 - Carboxypeptidase regulatory domain-like
  • 1Inherited
    81698,81698
  • 81698 - FF domain
  • 81698 - FF domain
  • 1Inherited
    56176,55103
  • 56176 - FAD-binding/transporter-associated domain-like
  • 55103 - FAD-linked oxidases, C-terminal domain
  • 1Inherited
    50447,54980
  • 50447 - Translation proteins
  • 54980 - EF-G C-terminal domain-like
  • 1Inherited
    90257,90257
  • 90257 - Myosin rod fragments
  • 90257 - Myosin rod fragments
  • 1Inherited
    57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 1Inherited
    57362,57362
  • 57362 - BPTI-like
  • 57362 - BPTI-like
  • 1Inherited
    52540,90123
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 90123 - ABC transporter transmembrane region
  • 1Inherited
    161093,161093
  • 161093 - MgtE membrane domain-like
  • 161093 - MgtE membrane domain-like
  • 1Inherited
    56436,56436
  • 56436 - C-type lectin-like
  • 56436 - C-type lectin-like
  • 1Inherited
    55785,55785
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55785 - PYP-like sensor domain (PAS domain)
  • 1Inherited
    47473,51695
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 1Inherited
    81333,81333
  • 81333 - F1F0 ATP synthase subunit C
  • 81333 - F1F0 ATP synthase subunit C
  • 1Inherited
    54292,47741
  • 54292 - 2Fe-2S ferredoxin-like
  • 47741 - CO dehydrogenase ISP C-domain like
  • 1Inherited
    49562,48371
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 1Inherited
    52283,51735
  • 52283 - Formate/glycerate dehydrogenase catalytic domain-like
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 1Inherited
    52374,52374
  • 52374 - Nucleotidylyl transferase
  • 52374 - Nucleotidylyl transferase
  • 1Inherited
    54495,57850
  • 54495 - UBC-like
  • 57850 - RING/U-box
  • 1Inherited
    55753,55753
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 1Inherited
    48034,55931
  • 48034 - Guanido kinase N-terminal domain
  • 55931 - Glutamine synthetase/guanido kinase
  • 1Inherited
    88713,88688
  • 88713 - Glycoside hydrolase/deacetylase
  • 88688 - Families 57/38 glycoside transferase middle domain
  • 1Inherited
    55973,55973
  • 55973 - S-adenosylmethionine synthetase
  • 55973 - S-adenosylmethionine synthetase
  • 1Inherited
    54980,54211
  • 54980 - EF-G C-terminal domain-like
  • 54211 - Ribosomal protein S5 domain 2-like
  • 1Inherited
    51126,51126
  • 51126 - Pectin lyase-like
  • 51126 - Pectin lyase-like
  • 1Inherited
    56112,56112
  • 56112 - Protein kinase-like (PK-like)
  • 56112 - Protein kinase-like (PK-like)
  • 1Inherited
    81383,50978
  • 81383 - F-box domain
  • 50978 - WD40 repeat-like
  • 1Inherited
    54368,55931
  • 54368 - Glutamine synthetase, N-terminal domain
  • 55931 - Glutamine synthetase/guanido kinase
  • 1Inherited
    56672,100879
  • 56672 - DNA/RNA polymerases
  • 100879 - Lesion bypass DNA polymerase (Y-family), little finger domain
  • 1Inherited
    68923,53795
  • 68923 - PEP carboxykinase N-terminal domain
  • 53795 - PEP carboxykinase-like
  • 1Inherited
    57850,117839
  • 57850 - RING/U-box
  • 117839 - WWE domain
  • 1Inherited
    49348,55711
  • 49348 - Clathrin adaptor appendage domain
  • 55711 - Subdomain of clathrin and coatomer appendage domain
  • 1Inherited
    49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 1Inherited
    54631,54631
  • 54631 - CBS-domain pair
  • 54631 - CBS-domain pair
  • 1Inherited
    64593,74853
  • 64593 - Intermediate filament protein, coiled coil region
  • 74853 - Lamin A/C globular tail domain
  • 1Inherited
    103473,100895
  • 103473 - MFS general substrate transporter
  • 100895 - Kazal-type serine protease inhibitors
  • 1Inherited
    52821,52821
  • 52821 - Rhodanese/Cell cycle control phosphatase
  • 52821 - Rhodanese/Cell cycle control phosphatase
  • 1Inherited
    50978,50978
  • 50978 - WD40 repeat-like
  • 50978 - WD40 repeat-like
  • 1Inherited
    54236,54236
  • 54236 - Ubiquitin-like
  • 54236 - Ubiquitin-like
  • 1Inherited
    101912,103575
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 1Inherited
    54534,54534
  • 54534 - FKBP-like
  • 54534 - FKBP-like
  • 1Inherited
    144232,82199
  • 144232 - HIT/MYND zinc finger-like
  • 82199 - SET domain
  • 1Inherited
    50044,52540
  • 50044 - SH3-domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 1Inherited
    49742,49742
  • 49742 - PHM/PNGase F
  • 49742 - PHM/PNGase F
  • 1Inherited
    52540,81271
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 81271 - TGS-like
  • 1Inherited
    50156,50044
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 1Inherited
    50729,47473
  • 50729 - PH domain-like
  • 47473 - EF-hand
  • 1Inherited
    46938,52087
  • 46938 - CRAL/TRIO N-terminal domain
  • 52087 - CRAL/TRIO domain
  • 1Inherited
    56968,48431
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 48431 - Lipovitellin-phosvitin complex, superhelical domain
  • 1Inherited
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 1Inherited
    81660,56784
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 1Inherited
    81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 1Inherited
    55394,55394
  • 55394 - Bactericidal permeability-increasing protein, BPI
  • 55394 - Bactericidal permeability-increasing protein, BPI
  • 1Inherited
    49785,49785
  • 49785 - Galactose-binding domain-like
  • 49785 - Galactose-binding domain-like
  • 1Inherited
    54211,55060
  • 54211 - Ribosomal protein S5 domain 2-like
  • 55060 - GHMP Kinase, C-terminal domain
  • 1Inherited
    52113,52113
  • 52113 - BRCT domain
  • 52113 - BRCT domain
  • 1Inherited
    47413,46689
  • 47413 - lambda repressor-like DNA-binding domains
  • 46689 - Homeodomain-like
  • 1Inherited
    51445,51445
  • 51445 - (Trans)glycosidases
  • 51445 - (Trans)glycosidases
  • 1Inherited
    47769,47769
  • 47769 - SAM/Pointed domain
  • 47769 - SAM/Pointed domain
  • 1Inherited
    54211,54980
  • 54211 - Ribosomal protein S5 domain 2-like
  • 54980 - EF-G C-terminal domain-like
  • 1Inherited
    81324,81327
  • 81324 - Voltage-gated potassium channels
  • 81327 - Small-conductance potassium channel
  • 1Inherited
    48065,50729
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 1Inherited
    49265,48726
  • 49265 - Fibronectin type III
  • 48726 - Immunoglobulin
  • 1Inherited
    52047,48371
  • 52047 - RNI-like
  • 48371 - ARM repeat
  • 1Inherited
    46785,46785
  • 46785 - "Winged helix" DNA-binding domain
  • 46785 - "Winged helix" DNA-binding domain
  • 1Inherited
    54897,52743
  • 54897 - Protease propeptides/inhibitors
  • 52743 - Subtilisin-like
  • 1Inherited
    47090,55486
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 1Inherited
    47473,103506
  • 47473 - EF-hand
  • 103506 - Mitochondrial carrier
  • 1Inherited
    52540,140990
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 140990 - FtsH protease domain-like
  • 1Inherited
    56059,51246
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 51246 - Rudiment single hybrid motif
  • 1Inherited
    56645,47203
  • 56645 - Acyl-CoA dehydrogenase NM domain-like
  • 47203 - Acyl-CoA dehydrogenase C-terminal domain-like
  • 1Inherited
    55920,46785
  • 55920 - Creatinase/aminopeptidase
  • 46785 - "Winged helix" DNA-binding domain
  • 1Inherited
    53448,50370
  • 53448 - Nucleotide-diphospho-sugar transferases
  • 50370 - Ricin B-like lectins
  • 1Inherited
    57850,57845
  • 57850 - RING/U-box
  • 57845 - B-box zinc-binding domain
  • 1Inherited
    50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 1Inherited
    74650,51445
  • 74650 - Galactose mutarotase-like
  • 51445 - (Trans)glycosidases
  • 1Inherited
    49562,49562
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 1Inherited
    46689,46689
  • 46689 - Homeodomain-like
  • 46689 - Homeodomain-like
  • 1Inherited
    52540,50447
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 1Inherited
    52833,52833
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 1Inherited
    51556,51338
  • 51556 - Metallo-dependent hydrolases
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 1Inherited
    47587,56399
  • 47587 - Domain of poly(ADP-ribose) polymerase
  • 56399 - ADP-ribosylation
  • 1Inherited
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 1Inherited
    54928,54928
  • 54928 - RNA-binding domain, RBD
  • 54928 - RNA-binding domain, RBD
  • 1Inherited
    57903,57903
  • 57903 - FYVE/PHD zinc finger
  • 57903 - FYVE/PHD zinc finger
  • 1Inherited
    54160,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 1Inherited
    50677,52374
  • 50677 - ValRS/IleRS/LeuRS editing domain
  • 52374 - Nucleotidylyl transferase
  • 1Inherited
    48464,89009
  • 48464 - ENTH/VHS domain
  • 89009 - GAT-like domain
  • 1Inherited
    55550,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 1Inherited
    53300,53300
  • 53300 - vWA-like
  • 53300 - vWA-like
  • 1Inherited
    51905,51905
  • 51905 - FAD/NAD(P)-binding domain
  • 51905 - FAD/NAD(P)-binding domain
  • 1Inherited
    47031,50729
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 1Inherited
    54236,47031
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 1Inherited
    81324,81296
  • 81324 - Voltage-gated potassium channels
  • 81296 - E set domains
  • 1Inherited
    46785,144074
  • 46785 - "Winged helix" DNA-binding domain
  • 144074 - E2F-DP heterodimerization region
  • 1Inherited
    52540,47917
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase
  • 1Inherited
    54585,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 1Inherited
    51445,54556
  • 51445 - (Trans)glycosidases
  • 54556 - Chitinase insertion domain
  • 1Inherited
    51905,55424
  • 51905 - FAD/NAD(P)-binding domain
  • 55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain
  • 1Inherited
    50978,50998
  • 50978 - WD40 repeat-like
  • 50998 - Quinoprotein alcohol dehydrogenase-like
  • 1Inherited
    51338,51556
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 51556 - Metallo-dependent hydrolases
  • 1Inherited
    48425,50729
  • 48425 - Sec7 domain
  • 50729 - PH domain-like
  • 1Inherited
    56112,82615
  • 56112 - Protein kinase-like (PK-like)
  • 82615 - Polo-box domain
  • 1Inherited
    49899,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 1Inherited
    49363,56300
  • 49363 - Purple acid phosphatase, N-terminal domain
  • 56300 - Metallo-dependent phosphatases
  • 1Inherited
    56112,55073
  • 56112 - Protein kinase-like (PK-like)
  • 55073 - Nucleotide cyclase
  • 1Inherited
    54211,55666
  • 54211 - Ribosomal protein S5 domain 2-like
  • 55666 - Ribonuclease PH domain 2-like
  • 1Inherited
    57889,57889
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 1Inherited
    52743,49785
  • 52743 - Subtilisin-like
  • 49785 - Galactose-binding domain-like
  • 1Inherited
    52047,52047
  • 52047 - RNI-like
  • 52047 - RNI-like
  • 1Inherited
    57625,57625
  • 57625 - Invertebrate chitin-binding proteins
  • 57625 - Invertebrate chitin-binding proteins
  • 1Inherited
    55550,50044
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 1Inherited
    47923,47923
  • 47923 - Ypt/Rab-GAP domain of gyp1p
  • 47923 - Ypt/Rab-GAP domain of gyp1p
  • 1Inherited
    49599,49599
  • 49599 - TRAF domain-like
  • 49599 - TRAF domain-like
  • 1Inherited
    51445,51011
  • 51445 - (Trans)glycosidases
  • 51011 - Glycosyl hydrolase domain
  • 1Inherited
    52440,56059
  • 52440 - PreATP-grasp domain
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 1Inherited
    57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 1Inherited
    51735,48179
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
  • 1Inherited
    57850,57850
  • 57850 - RING/U-box
  • 57850 - RING/U-box
  • 1Inherited
    55729,55729
  • 55729 - Acyl-CoA N-acyltransferases (Nat)
  • 55729 - Acyl-CoA N-acyltransferases (Nat)
  • 1Inherited
    103025,101790
  • 103025 - Folate-binding domain
  • 101790 - Aminomethyltransferase beta-barrel domain
  • 1Inherited
    57567,57567
  • 57567 - Serine protease inhibitors
  • 57567 - Serine protease inhibitors
  • 1Inherited
    52777,52777
  • 52777 - CoA-dependent acyltransferases
  • 52777 - CoA-dependent acyltransferases
  • 1Inherited
    103473,103473
  • 103473 - MFS general substrate transporter
  • 103473 - MFS general substrate transporter
  • 1Inherited
    54768,54768
  • 54768 - dsRNA-binding domain-like
  • 54768 - dsRNA-binding domain-like
  • 1Inherited
    57196,49899
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 1Inherited
    47203,47203
  • 47203 - Acyl-CoA dehydrogenase C-terminal domain-like
  • 47203 - Acyl-CoA dehydrogenase C-terminal domain-like
  • 1Inherited
    57903,51197
  • 57903 - FYVE/PHD zinc finger
  • 51197 - Clavaminate synthase-like
  • 1Inherited
    57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 1Inherited
    82895,82895
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 1Inherited
    56024,56024
  • 56024 - Phospholipase D/nuclease
  • 56024 - Phospholipase D/nuclease
  • 1Inherited
    48179,48179
  • 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
  • 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
  • 1Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 1Inherited
    52540,50447,54980
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 54980 - EF-G C-terminal domain-like
  • 1Inherited
    57362,57362,57362
  • 57362 - BPTI-like
  • 57362 - BPTI-like
  • 57362 - BPTI-like
  • 1Inherited
    52540,90123,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 1Inherited
    48726,49265,48726
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 48726 - Immunoglobulin
  • 1Inherited
    50156,50044,52540
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 1Inherited
    81301,81631,55003
  • 81301 - Nucleotidyltransferase
  • 81631 - PAP/OAS1 substrate-binding domain
  • 55003 - PAP/Archaeal CCA-adding enzyme, C-terminal domain
  • 1Inherited
    54160,52540,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 1Inherited
    51735,48179,48179
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
  • 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
  • 1Inherited
    56968,48431,56968
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 48431 - Lipovitellin-phosvitin complex, superhelical domain
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 1Inherited
    63411,63411,63411
  • 63411 - LuxS/MPP-like metallohydrolase
  • 63411 - LuxS/MPP-like metallohydrolase
  • 63411 - LuxS/MPP-like metallohydrolase
  • 1Inherited
    90257,90257,90257
  • 90257 - Myosin rod fragments
  • 90257 - Myosin rod fragments
  • 90257 - Myosin rod fragments
  • 1Inherited
    56112,82615,82615
  • 56112 - Protein kinase-like (PK-like)
  • 82615 - Polo-box domain
  • 82615 - Polo-box domain
  • 1Inherited
    82895,82895,82895
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 1Inherited
    74650,51445,51011
  • 74650 - Galactose mutarotase-like
  • 51445 - (Trans)glycosidases
  • 51011 - Glycosyl hydrolase domain
  • 1Inherited
    50692,54585,52540
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 1Inherited
    49313,49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 1Inherited
    50447,54980,54211
  • 50447 - Translation proteins
  • 54980 - EF-G C-terminal domain-like
  • 54211 - Ribosomal protein S5 domain 2-like
  • 1Inherited
    46966,46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 1Inherited
    49562,48371,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 1Inherited
    54791,54791,54791
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 1Inherited
    50044,55550,56112
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 1Inherited
    48452,48452,48452
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 1Inherited
    49599,49599,49599
  • 49599 - TRAF domain-like
  • 49599 - TRAF domain-like
  • 49599 - TRAF domain-like
  • 1Inherited
    54980,54211,54980
  • 54980 - EF-G C-terminal domain-like
  • 54211 - Ribosomal protein S5 domain 2-like
  • 54980 - EF-G C-terminal domain-like
  • 1Inherited
    50129,51735,50129
  • 50129 - GroES-like
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 50129 - GroES-like
  • 1Inherited
    49785,49785,49785
  • 49785 - Galactose-binding domain-like
  • 49785 - Galactose-binding domain-like
  • 49785 - Galactose-binding domain-like
  • 1Inherited
    48371,48371,48371
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 1Inherited
    52058,52058,52058
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 1Inherited
    81660,56784,81665
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 81665 - Calcium ATPase, transmembrane domain M
  • 1Inherited
    57414,57414,57414
  • 57414 - Hairpin loop containing domain-like
  • 57414 - Hairpin loop containing domain-like
  • 57414 - Hairpin loop containing domain-like
  • 1Inherited
    90123,52540,90123
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 90123 - ABC transporter transmembrane region
  • 1Inherited
    81296,81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 81296 - E set domains
  • 1Inherited
    57625,57625,57625
  • 57625 - Invertebrate chitin-binding proteins
  • 57625 - Invertebrate chitin-binding proteins
  • 57625 - Invertebrate chitin-binding proteins
  • 1Inherited
    54928,54928,54928
  • 54928 - RNA-binding domain, RBD
  • 54928 - RNA-binding domain, RBD
  • 54928 - RNA-binding domain, RBD
  • 1Inherited
    55973,55973,55973
  • 55973 - S-adenosylmethionine synthetase
  • 55973 - S-adenosylmethionine synthetase
  • 55973 - S-adenosylmethionine synthetase
  • 1Inherited
    47090,55486,50923
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 1Inherited
    52833,52833,52833
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 1Inherited
    46938,52087,101576
  • 46938 - CRAL/TRIO N-terminal domain
  • 52087 - CRAL/TRIO domain
  • 101576 - Supernatant protein factor (SPF), C-terminal domain
  • 1Inherited
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 1Inherited
    50729,47473,51695
  • 50729 - PH domain-like
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 1Inherited
    54585,52540,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 1Inherited
    57567,57567,57567
  • 57567 - Serine protease inhibitors
  • 57567 - Serine protease inhibitors
  • 57567 - Serine protease inhibitors
  • 1Inherited
    54160,54160,52540
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 1Inherited
    52540,50447,50465
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
  • 1Inherited
    57850,57850,57850
  • 57850 - RING/U-box
  • 57850 - RING/U-box
  • 57850 - RING/U-box
  • 1Inherited
    56436,49854,49854
  • 56436 - C-type lectin-like
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 1Inherited
    57535,57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 1Inherited
    54292,47741,56176
  • 54292 - 2Fe-2S ferredoxin-like
  • 47741 - CO dehydrogenase ISP C-domain like
  • 56176 - FAD-binding/transporter-associated domain-like
  • 1Inherited
    49899,49899,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 1Inherited
    48726,48726,49265
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 1Inherited
    54897,52743,49785
  • 54897 - Protease propeptides/inhibitors
  • 52743 - Subtilisin-like
  • 49785 - Galactose-binding domain-like
  • 1Inherited
    52440,56059,51246
  • 52440 - PreATP-grasp domain
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 51246 - Rudiment single hybrid motif
  • 1Inherited
    50044,50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 1Inherited
    56645,47203,47203
  • 56645 - Acyl-CoA dehydrogenase NM domain-like
  • 47203 - Acyl-CoA dehydrogenase C-terminal domain-like
  • 47203 - Acyl-CoA dehydrogenase C-terminal domain-like
  • 1Inherited
    57716,57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 1Inherited
    56436,56436,49854
  • 56436 - C-type lectin-like
  • 56436 - C-type lectin-like
  • 49854 - Spermadhesin, CUB domain
  • 1Inherited
    54236,47031,50729
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 1Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)