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Worm Phenotype (WP): gene expression variant

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Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)

Shortest distance to current term (+ for parents, - for children) WP term [WP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + 5:   Variant [WBPhenotype:0000886] <2>
+ + + + 4:   physiology variant [WBPhenotype:0000519] <14>(510|587) (510|248|69)
+ + + 3:   organism physiology variant [WBPhenotype:0000576] <9>(369|431) (372|193|57)
+ + 2:   organism homeostasis metabolism variant [WBPhenotype:0000577] <16>(361|421) (363|190|56)
+ 1:   organism metabolism processing variant [WBPhenotype:0000027] <25>(178|190) (182|87|26)
0:   gene expression variant [WBPhenotype:0000717] <11>(127|139) (131|64|20)
- 1:   RNA expression variant [WBPhenotype:0000113] <10>(20|16) (20|5|0)
- 1:   protein expression variant [WBPhenotype:0000112] <6>(39|44) (41|19|6)
- 1:   dosage compensation variant [WBPhenotype:0000718] <3>(1|0) (1|0|0)
- 1:   transgene expression variant [WBPhenotype:0000306] <3>(82|99) (85|43|14)
- 1:   antimicrobial gene expression variant [WBPhenotype:0002534] <2>(8|9) (9|3|1)
- 1:   gene expression level high [WBPhenotype:0000135] <1>(2|2) (2|0|0)
- 1:   gene expression level reduced [WBPhenotype:0000134] <1>(6|3) (6|0|0)
- 1:   pathogen induced gene expression variant [WBPhenotype:0001857] <1>(8|9) (9|3|1)
- 1:   drug induced gene expression variant [WBPhenotype:0001838](5|6) (5|2|0)
- 1:   environmental stimuli induced gene expression variant [WBPhenotype:0001861](0|0) (0|0|0)
- 1:   pattern of gene expression variant [WBPhenotype:0000111](0|0) (0|0|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
SMAD MH1 domain0Direct
Helical domain of Sec23/240Direct
JAB1/MPN domain0Direct
S-adenosylmethionine synthetase0Direct
Histone-fold0Direct
Cu,Zn superoxide dismutase-like0Direct
ISP domain0Direct
Tubulin C-terminal domain-like0Direct
MIR domain0Direct
Subdomain of clathrin and coatomer appendage domain0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Ribosomal protein L10Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Epsilon subunit of mitochondrial F1F0-ATP synthase0Direct
Heme-dependent catalase-like0Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0Direct
Ribosomal proteins S24e, L23 and L15e0Direct
Tubulin nucleotide-binding domain-like0Direct
Class II aaRS ABD-related0Direct
Cytochrome c0Direct
TK C-terminal domain-like0Direct
GroEL apical domain-like0Direct
Nop domain0Direct
Sec1/munc18-like (SM) proteins0Direct
FF domain0Direct
Cullin homology domain0Direct
ValRS/IleRS/LeuRS editing domain0Direct
Zn-finger domain of Sec23/240Direct
F1F0 ATP synthase subunit C0Direct
HSP90 C-terminal domain0Direct
GroEL equatorial domain-like0Direct
Heat shock protein 70kD (HSP70), C-terminal subdomain0Direct
Clathrin adaptor appendage domain0Direct
14-3-3 protein0Direct
C-terminal, gelsolin-like domain of Sec23/240Direct
GroEL-intermediate domain like0Direct
Ribosomal protein L10-like0Direct
Chromo domain-like0.0000000003011Direct
FYVE/PHD zinc finger0.00000001509Direct
SET domain0.0000001122Direct
Acid proteases0.000003547Direct
Class II aaRS and biotin synthetases0.000003547Direct
RING/U-box0.000003587Direct
Cysteine-rich domain0.000004036Direct
SNARE-like0.000009056Direct
PAP/OAS1 substrate-binding domain0.00001687Direct
Translation proteins0.0000179Direct
Bromodomain0.00004617Direct
Translation proteins SH3-like domain0.00007551Direct
Cullin repeat-like0.00008984Direct
Hect, E3 ligase catalytic domain0.00008984Direct
Arginase/deacetylase0.00008984Direct
Heat shock protein 70kD (HSP70), peptide-binding domain0.00008984Direct
CCCH zinc finger0.0001059Direct
B-box zinc-binding domain0.0002005Direct
ARM repeat0.0002129Direct
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.0002261Direct
Retrovirus zinc finger-like domains0.000422Direct
Cyclophilin-like0.000483Direct
ACP-like0.0008353Direct
Sm-like ribonucleoproteins0.001187Inherited
"Winged helix" DNA-binding domain0.001277Inherited
RNA-binding domain, RBD0.001277Inherited
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0.001633Inherited
L30e-like0.001633Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.002187Inherited
beta and beta-prime subunits of DNA dependent RNA-polymerase0.002503Inherited
Tudor/PWWP/MBT0.002642Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.004374Inherited
Riboflavin synthase domain-like0.004374Inherited
PAZ domain0.005318Inherited
FKBP-like0.00543Inherited
P-loop containing nucleoside triphosphate hydrolases0.005826Inherited
4Fe-4S ferredoxins0.007402Inherited
Frizzled cysteine-rich domain0.007402Inherited
Leucine zipper domain0.00788Inherited
Cyclin-like0.009727Inherited
Zn-binding ribosomal proteins0.0114Inherited
dsRNA-binding domain-like0.01207Inherited
DHS-like NAD/FAD-binding domain0.01308Inherited
Single hybrid motif0.01337Inherited
Saposin0.02015Inherited
ADC-like0.02151Inherited
Cdc48 domain 2-like0.02151Inherited
Integrin domains0.02151Inherited
HIT/MYND zinc finger-like0.02463Inherited
p53-like transcription factors0.02563Inherited
PH domain-like0.02624Inherited
PX domain0.02725Inherited
Homeodomain-like0.03178Inherited
SH3-domain0.03201Inherited
UBC-like0.03651Inherited
Chaperone J-domain0.04749Inherited
Actin-like ATPase domain0.04749Inherited
HLH, helix-loop-helix DNA-binding domain0.05409Inherited
Protein kinase-like (PK-like)0.06419Inherited
PDZ domain-like0.06821Inherited
Tubby C-terminal domain-like0.07094Inherited
CAD & PB1 domains0.07094Inherited
S15/NS1 RNA-binding domain0.07094Inherited
ARID-like0.07094Inherited
Quinoprotein alcohol dehydrogenase-like0.08286Inherited
Nucleic acid-binding proteins0.08702Inherited
HSP20-like chaperones0.09075Inherited
SAM/Pointed domain0.1429Inherited
KA1-like0.1452Inherited
Cysteine proteinases0.151Inherited
GTPase activation domain, GAP0.1903Inherited
Nucleotidyltransferase0.2196Inherited
Eukaryotic type KH-domain (KH-domain type I)0.248Inherited
HMG-box0.248Inherited
Transducin (alpha subunit), insertion domain0.248Inherited
WD40 repeat-like0.2613Inherited
SH2 domain0.2753Inherited
Second domain of FERM0.3901Inherited
Nucleotidylyl transferase0.4106Inherited
Intermediate filament protein, coiled coil region0.4505Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.4538Inherited
C2 domain (Calcium/lipid-binding domain, CaLB)0.4945Inherited
Activating enzymes of the ubiquitin-like proteins0.5043Inherited
PYP-like sensor domain (PAS domain)0.5043Inherited
Lamin A/C globular tail domain0.5043Inherited
Spectrin repeat0.5043Inherited
Ribonuclease H-like0.5938Inherited
Clavaminate synthase-like0.6933Inherited
Nuclear receptor ligand-binding domain0.9377Inherited
ClpP/crotonase1Inherited


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Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Trunk domain of Sec23/240Direct
Ribosomal protein L10Direct
Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta0Direct
Integrin domains0Direct
Acyl-carrier protein (ACP)0Direct
Phoshoinositide 3-kinase (PI3K) helical domain0Direct
Hsp90 middle domain0Direct
S-adenosylmethionine synthetase0Direct
ValRS/IleRS/LeuRS editing domain0Direct
Helical domain of Sec23/240Direct
Heat shock protein 70kD (HSP70), C-terminal subdomain0Direct
p120GAP domain-like0Direct
Ubiquitin carboxyl-terminal hydrolase UCH-L0Direct
HSP90 C-terminal domain0Direct
beta-sandwich domain of Sec23/240Direct
Cullin repeat0Direct
HSP200Direct
Group II chaperonin (CCT, TRIC), ATPase domain0Direct
Anticodon-binding domain of Class II aaRS0Direct
CAT-like0Direct
Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain0Direct
L30e/L7ae ribosomal proteins0Direct
Smc hinge domain0Direct
Cu,Zn superoxide dismutase-like0Direct
F1F0 ATP synthase subunit C0Direct
Mammalian PLC0Direct
Sec1/munc18-like (SM) proteins0Direct
SCF ubiquitin ligase complex WHB domain0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
POU-specific domain0Direct
Erythroid transcription factor GATA-10Direct
Clathrin coat assembly domain0Direct
RNA-polymerase beta0Direct
Inositol polyphosphate 5-phosphatase (IPP5)0Direct
PDI-like0Direct
Group II chaperonin (CCT, TRIC), intermediate domain0Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0Direct
ets domain0Direct
Epsilon subunit of mitochondrial F1F0-ATP synthase0Direct
a tRNA synthase domain0Direct
Sir2 family of transcriptional regulators0Direct
Chromo domain0Direct
Proteasome subunits0Direct
FF domain0Direct
14-3-3 protein0Direct
SMAD MH1 domain0Direct
Tubulin, C-terminal domain0Direct
MIF4G domain-like0Direct
Quinoprotein alcohol dehydrogenase-like0Direct
Clathrin adaptor core protein0Direct
Tubulin, GTPase domain0Direct
Heme-dependent catalases0Direct
Brix domain0Direct
Nop domain0Direct
Histone deacetylase, HDAC0Direct
Cullin homology domain0Direct
MIR domain0Direct
Adenain-like0Direct
C-terminal, gelsolin-like domain of Sec23/240Direct
RNA editing terminal uridyl transferase 2, RET2, domain 20Direct
Heat shock protein 90, HSP90, N-terminal domain0Direct
Zn-finger domain of Sec23/240Direct
RecA protein-like (ATPase-domain)0Direct
Phoshoinositide 3-kinase (PI3K), catalytic domain0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Group II chaperonin (CCT, TRIC), apical domain0Direct
Nucleosome core histones0.00000000000000313Direct
Actin/HSP700.000000004466Direct
UBC-related0.000000082Direct
Forkhead DNA-binding domain0.0000003019Direct
Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain0.000001278Direct
PHD domain0.000001311Direct
Pepsin-like0.00000323Direct
Dual specificity phosphatase-like0.00000323Direct
Histone lysine methyltransferases0.00004364Direct
Papain-like0.00005176Direct
Ubiquitin carboxyl-terminal hydrolase, UCH0.00006768Direct
Class I aminoacyl-tRNA synthetases (RS), catalytic domain0.0001655Direct
Bromodomain0.0002386Direct
Hect, E3 ligase catalytic domain0.000283Direct
Protein kinase cysteine-rich domain (cys2, phorbol-binding domain)0.0003001Direct
Armadillo repeat0.0003041Direct
Heat shock protein 70kD (HSP70), peptide-binding domain0.0007409Direct
Translational machinery components0.0007409Direct
SMAD domain0.0007409Direct
CCCH zinc finger0.0009017Direct
B-box zinc-binding domain0.001043Inherited
Cyclophilin (peptidylprolyl isomerase)0.002161Inherited
TBP-associated factors, TAFs0.002776Inherited
Cold shock DNA-binding domain-like0.003009Inherited
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0.004153Inherited
Canonical RBD0.004165Inherited
PDZ domain0.005605Inherited
Sm motif of small nuclear ribonucleoproteins, SNRNP0.00761Inherited
Extended PAW domain0.008725Inherited
Transforming growth factor (TGF)-beta0.01284Inherited
Ubiquitin activating enzymes (UBA)0.01284Inherited
EF-hand modules in multidomain proteins0.01284Inherited
Frizzled cysteine-rich domain0.01284Inherited
FKBP immunophilin/proline isomerase0.01308Inherited
Pumilio repeat0.01308Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.01308Inherited
Elongation factors0.01822Inherited
Cyclin0.01822Inherited
Homeodomain0.0192Inherited
RING finger domain, C3HC40.0226Inherited
PAZ domain0.02673Inherited
Leucine zipper domain0.02951Inherited
Biotinyl/lipoyl-carrier proteins and domains0.0308Inherited
Biotin dependent carboxylase carboxyltransferase domain0.03282Inherited
Cdc48 N-terminal domain-like0.03282Inherited
Anticodon-binding domain0.03282Inherited
Cdc48 domain 2-like0.03282Inherited
Chaperone J-domain0.04384Inherited
HLH, helix-loop-helix DNA-binding domain0.04997Inherited
PX domain0.05956Inherited
SH3-domain0.07506Inherited
DEP domain0.1046Inherited
WD40-repeat0.11Inherited
Pleckstrin-homology domain (PH domain)0.1544Inherited
G proteins0.2046Inherited
First domain of FERM0.2078Inherited
Extended AAA-ATPase domain0.2299Inherited
Transducin (alpha subunit), insertion domain0.2341Inherited
PLC-like (P variant)0.3401Inherited
N-acetyl transferase, NAT0.3658Inherited
Double-stranded RNA-binding domain (dsRBD)0.3962Inherited
Third domain of FERM0.3962Inherited
Intermediate filament protein, coiled coil region0.4336Inherited
Second domain of FERM0.4854Inherited
Synaptotagmin-like (S variant)0.4854Inherited
LIM domain0.4871Inherited
Protein kinases, catalytic subunit0.5024Inherited
Lamin A/C globular tail domain0.547Inherited
Spectrin repeat0.547Inherited
Ubiquitin-related0.584Inherited
SH2 domain0.6274Inherited
Nuclear receptor1Inherited
Nuclear receptor ligand-binding domain1Inherited


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Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
14-3-3 protein0Direct
GroEL equatorial domain-like0Direct
Tubulin nucleotide-binding domain-like0Direct
Cullin homology domain0Direct
Ribosomal protein L10Direct
TK C-terminal domain-like0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Class II aaRS ABD-related0Direct
FF domain0Direct
Histone-fold0Direct
F1F0 ATP synthase subunit C0Direct
C-terminal, gelsolin-like domain of Sec23/240Direct
Cu,Zn superoxide dismutase-like0Direct
Cytochrome c0Direct
S-adenosylmethionine synthetase0Direct
Heat shock protein 70kD (HSP70), C-terminal subdomain0Direct
ISP domain0Direct
MIR domain0Direct
HSP90 C-terminal domain0Direct
Sec1/munc18-like (SM) proteins0Direct
Clathrin adaptor appendage domain0Direct
Ribosomal protein L10-like0Direct
Ribosomal proteins S24e, L23 and L15e0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0Direct
Zn-finger domain of Sec23/240Direct
GroEL apical domain-like0Direct
SMAD MH1 domain0Direct
Heme-dependent catalase-like0Direct
Helical domain of Sec23/240Direct
JAB1/MPN domain0Direct
Nop domain0Direct
ValRS/IleRS/LeuRS editing domain0Direct
GroEL-intermediate domain like0Direct
Epsilon subunit of mitochondrial F1F0-ATP synthase0Direct
Tubulin C-terminal domain-like0Direct
Subdomain of clathrin and coatomer appendage domain0Direct
Chromo domain-like0.0000000002386Direct
FYVE/PHD zinc finger0.00000001203Direct
SET domain0.0000000898Direct
Acid proteases0.000002878Direct
Class II aaRS and biotin synthetases0.000002878Direct
RING/U-box0.000002912Direct
Cysteine-rich domain0.000003277Direct
SNARE-like0.000007364Direct
PAP/OAS1 substrate-binding domain0.00001375Direct
Translation proteins0.00001459Direct
Bromodomain0.00003773Direct
Translation proteins SH3-like domain0.00006177Direct
Heat shock protein 70kD (HSP70), peptide-binding domain0.00007356Direct
Cullin repeat-like0.00007356Direct
Arginase/deacetylase0.00007356Direct
Hect, E3 ligase catalytic domain0.00007356Direct
CCCH zinc finger0.00008677Direct
B-box zinc-binding domain0.0001646Direct
ARM repeat0.0001749Direct
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.0001858Direct
Retrovirus zinc finger-like domains0.0003484Direct
Cyclophilin-like0.0003995Direct
ACP-like0.0006944Direct
ENTH/VHS domain0.0008681Direct
Sm-like ribonucleoproteins0.0009887Direct
"Winged helix" DNA-binding domain0.001065Inherited
RNA-binding domain, RBD0.001065Inherited
L30e-like0.001365Inherited
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0.001365Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.001837Inherited
beta and beta-prime subunits of DNA dependent RNA-polymerase0.002107Inherited
Tudor/PWWP/MBT0.002226Inherited
Riboflavin synthase domain-like0.003707Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.003707Inherited
PAZ domain0.00452Inherited
FKBP-like0.004616Inherited
P-loop containing nucleoside triphosphate hydrolases0.004958Inherited
Frizzled cysteine-rich domain0.006321Inherited
4Fe-4S ferredoxins0.006321Inherited
Leucine zipper domain0.006739Inherited
Cyclin-like0.008359Inherited
Zn-binding ribosomal proteins0.009822Inherited
dsRNA-binding domain-like0.0104Inherited
DHS-like NAD/FAD-binding domain0.01129Inherited
Single hybrid motif0.01155Inherited
Saposin0.01752Inherited
Cdc48 domain 2-like0.01873Inherited
Integrin domains0.01873Inherited
ADC-like0.01873Inherited
HIT/MYND zinc finger-like0.02152Inherited
p53-like transcription factors0.02242Inherited
PH domain-like0.02296Inherited
PX domain0.02385Inherited
Homeodomain-like0.02792Inherited
SH3-domain0.02813Inherited
UBC-like0.03215Inherited
Chaperone J-domain0.04201Inherited
Actin-like ATPase domain0.04201Inherited
HLH, helix-loop-helix DNA-binding domain0.04803Inherited
Protein kinase-like (PK-like)0.05723Inherited
PDZ domain-like0.0609Inherited
CAD & PB1 domains0.0634Inherited
ARID-like0.0634Inherited
S15/NS1 RNA-binding domain0.0634Inherited
Tubby C-terminal domain-like0.0634Inherited
Quinoprotein alcohol dehydrogenase-like0.07441Inherited
Nucleic acid-binding proteins0.07822Inherited
HSP20-like chaperones0.08168Inherited
PLC-like phosphodiesterases0.1255Inherited
DNase I-like0.1255Inherited
SAM/Pointed domain0.1302Inherited
KA1-like0.1323Inherited
Cysteine proteinases0.1378Inherited
GTPase activation domain, GAP0.175Inherited
Nucleotidyltransferase0.2029Inherited
Transducin (alpha subunit), insertion domain0.2303Inherited
HMG-box0.2303Inherited
Eukaryotic type KH-domain (KH-domain type I)0.2303Inherited
WD40 repeat-like0.2433Inherited
SH2 domain0.2569Inherited
Second domain of FERM0.3696Inherited
Nucleotidylyl transferase0.3898Inherited
Intermediate filament protein, coiled coil region0.4295Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.4328Inherited
C2 domain (Calcium/lipid-binding domain, CaLB)0.4728Inherited
Activating enzymes of the ubiquitin-like proteins0.4824Inherited
PYP-like sensor domain (PAS domain)0.4824Inherited
Spectrin repeat0.4824Inherited
Lamin A/C globular tail domain0.4824Inherited
FAD/NAD-linked reductases, dimerisation (C-terminal) domain0.5465Inherited
Ribonuclease H-like0.5717Inherited
Clavaminate synthase-like0.6724Inherited
Nuclear receptor ligand-binding domain0.924Inherited
ClpP/crotonase1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
48592,54849
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 0Direct
    46785,46785
  • 46785 - "Winged helix" DNA-binding domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    52518,52922
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 52922 - TK C-terminal domain-like
  • 0Direct
    50692,54585
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 0Direct
    57903,82199
  • 57903 - FYVE/PHD zinc finger
  • 82199 - SET domain
  • 0Direct
    75632,46785
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    144232,82199
  • 144232 - HIT/MYND zinc finger-like
  • 82199 - SET domain
  • 0Direct
    54534,54534
  • 54534 - FKBP-like
  • 54534 - FKBP-like
  • 0Direct
    55973,55973
  • 55973 - S-adenosylmethionine synthetase
  • 55973 - S-adenosylmethionine synthetase
  • 0Direct
    57863,48403
  • 57863 - ArfGap/RecO-like zinc finger
  • 48403 - Ankyrin repeat
  • 0Direct
    55681,52954
  • 55681 - Class II aaRS and biotin synthetases
  • 52954 - Class II aaRS ABD-related
  • 0Direct
    49348,55711
  • 49348 - Clathrin adaptor appendage domain
  • 55711 - Subdomain of clathrin and coatomer appendage domain
  • 0Direct
    64356,49447
  • 64356 - SNARE-like
  • 49447 - Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor
  • 0Direct
    55785,55785
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0Direct
    82919,53300
  • 82919 - Zn-finger domain of Sec23/24
  • 53300 - vWA-like
  • 0Direct
    52540,47917
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase
  • 0Direct
    52490,55307
  • 52490 - Tubulin nucleotide-binding domain-like
  • 55307 - Tubulin C-terminal domain-like
  • 0Direct
    81698,81698
  • 81698 - FF domain
  • 81698 - FF domain
  • 0Direct
    50729,56112
  • 50729 - PH domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    50729,47473
  • 50729 - PH domain-like
  • 47473 - EF-hand
  • 0Direct
    51695,49562
  • 51695 - PLC-like phosphodiesterases
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0Direct
    54585,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    50677,52374
  • 50677 - ValRS/IleRS/LeuRS editing domain
  • 52374 - Nucleotidylyl transferase
  • 0Direct
    54160,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    54160,54160
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 0Direct
    55729,55729
  • 55729 - Acyl-CoA N-acyltransferases (Nat)
  • 55729 - Acyl-CoA N-acyltransferases (Nat)
  • 0Direct
    57756,57756
  • 57756 - Retrovirus zinc finger-like domains
  • 57756 - Retrovirus zinc finger-like domains
  • 0Direct
    49562,48371
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 0Direct
    81333,81333
  • 81333 - F1F0 ATP synthase subunit C
  • 81333 - F1F0 ATP synthase subunit C
  • 0Direct
    74788,75632
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 0Direct
    57903,51197
  • 57903 - FYVE/PHD zinc finger
  • 51197 - Clavaminate synthase-like
  • 0Direct
    81811,82754
  • 81811 - Helical domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0Direct
    100920,100934
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
  • 0Direct
    54495,46934
  • 54495 - UBC-like
  • 46934 - UBA-like
  • 0Direct
    47473,51695
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 0Direct
    54849,52029
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0Direct
    81301,81631
  • 81301 - Nucleotidyltransferase
  • 81631 - PAP/OAS1 substrate-binding domain
  • 0.000007364Direct
    47954,47954
  • 47954 - Cyclin-like
  • 47954 - Cyclin-like
  • 0.000007364Direct
    53067,100920
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 0.00007356Direct
    48452,48452
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 0.0004333Direct
    54928,54928
  • 54928 - RNA-binding domain, RBD
  • 54928 - RNA-binding domain, RBD
  • 0.0004333Direct
    101690,53098
  • 101690 - PAZ domain
  • 53098 - Ribonuclease H-like
  • 0.0006944Direct
    57889,57889
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 0.001365Inherited
    50447,50465
  • 50447 - Translation proteins
  • 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
  • 0.001365Inherited
    51045,51045
  • 51045 - WW domain
  • 51045 - WW domain
  • 0.002107Inherited
    52540,50447
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 0.002224Inherited
    57850,57845
  • 57850 - RING/U-box
  • 57845 - B-box zinc-binding domain
  • 0.005044Inherited
    48371,56112
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.006321Inherited
    90229,90229
  • 90229 - CCCH zinc finger
  • 90229 - CCCH zinc finger
  • 0.009507Inherited
    50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0.009822Inherited
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.009822Inherited
    55550,50044
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0.01873Inherited
    53067,53067
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 0.04201Inherited
    57850,57850
  • 57850 - RING/U-box
  • 57850 - RING/U-box
  • 0.04297Inherited
    50249,55681
  • 50249 - Nucleic acid-binding proteins
  • 55681 - Class II aaRS and biotin synthetases
  • 0.0634Inherited
    57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.1569Inherited
    47895,52540
  • 47895 - Transducin (alpha subunit), insertion domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.2303Inherited
    47031,50729
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.284Inherited
    52833,52833
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 0.3815Inherited
    54236,47031
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 0.5075Inherited
    51905,55424
  • 51905 - FAD/NAD(P)-binding domain
  • 55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain
  • 0.5465Inherited
    64593,74853
  • 64593 - Intermediate filament protein, coiled coil region
  • 74853 - Lamin A/C globular tail domain
  • 0.5465Inherited
    46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.6118Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.7589Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    54160,54160,52540
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    53067,100920,100934
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
  • 0Direct
    55973,55973,55973
  • 55973 - S-adenosylmethionine synthetase
  • 55973 - S-adenosylmethionine synthetase
  • 55973 - S-adenosylmethionine synthetase
  • 0Direct
    54585,52540,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    50692,54585,52540
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    54160,52540,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    48592,54849,52029
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0Direct
    49562,48371,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    48452,48452,48452
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 0Direct
    50729,47473,51695
  • 50729 - PH domain-like
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 0Direct
    74788,75632,46785
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    48371,48371,48371
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 0Direct
    53067,53067,100920
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 0.00007356Direct
    52540,50447,50465
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
  • 0.001365Inherited
    57850,57850,57850
  • 57850 - RING/U-box
  • 57850 - RING/U-box
  • 57850 - RING/U-box
  • 0.01129Inherited
    54236,47031,50729
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.4258Inherited
    57716,57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.4295Inherited
    52833,52833,52833
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 0.4295Inherited
    46966,46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.6118Inherited
    57424,57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.9659Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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