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Worm Phenotype (WP): gene expression variant

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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)

Shortest distance to current term (+ for parents, - for children) WP term [WP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + 5:   Variant [WBPhenotype:0000886] <5>
+ + + + 4:   physiology variant [WBPhenotype:0000519] <7>(494|573) (495|248|68)
+ + + 3:   organism physiology variant [WBPhenotype:0000576] <10>(354|423) (357|200|60)
+ + 2:   organism homeostasis metabolism variant [WBPhenotype:0000577] <17>(343|412) (348|198|59)
+ 1:   organism metabolism processing variant [WBPhenotype:0000027] <25>(167|178) (172|81|24)
0:   gene expression variant [WBPhenotype:0000717] <10>(121|132) (128|62|19)
- 1:   RNA expression variant [WBPhenotype:0000113] <10>(19|16) (19|5|0)
- 1:   protein expression variant [WBPhenotype:0000112] <6>(38|43) (40|20|6)
- 1:   dosage compensation variant [WBPhenotype:0000718] <3>(1|0) (1|0|0)
- 1:   transgene expression variant [WBPhenotype:0000306] <3>(83|93) (89|41|13)
- 1:   gene expression level high [WBPhenotype:0000135] <1>(2|2) (2|0|0)
- 1:   gene expression level reduced [WBPhenotype:0000134] <1>(5|3) (5|0|0)
- 1:   drug induced gene expression variant [WBPhenotype:0001838](5|6) (5|2|0)
- 1:   environmental stimuli induced gene expression variant [WBPhenotype:0001861](0|0) (0|0|0)
- 1:   pathogen induced gene expression variant [WBPhenotype:0001857](1|1) (1|0|0)
- 1:   pattern of gene expression variant [WBPhenotype:0000111](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Nop domain0Direct
14-3-3 protein0Direct
Cullin homology domain0Direct
Class II aaRS ABD-related0Direct
F1F0 ATP synthase subunit C0Direct
Helical domain of Sec23/240Direct
Subdomain of clathrin and coatomer appendage domain0Direct
TK C-terminal domain-like0Direct
ValRS/IleRS/LeuRS editing domain0Direct
S-adenosylmethionine synthetase0Direct
Zn-finger domain of Sec23/240Direct
GroEL-intermediate domain like0Direct
Heat shock protein 70kD (HSP70), C-terminal subdomain0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
GroEL apical domain-like0Direct
FF domain0Direct
Cytochrome c0Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0Direct
SMAD MH1 domain0Direct
GroEL equatorial domain-like0Direct
HSP90 C-terminal domain0Direct
Ribosomal protein L10Direct
Tubulin C-terminal domain-like0Direct
Tubulin nucleotide-binding domain-like0Direct
JAB1/MPN domain0Direct
Ribosomal protein L10-like0Direct
Clathrin adaptor appendage domain0Direct
Epsilon subunit of mitochondrial F1F0-ATP synthase0Direct
Heme-dependent catalase-like0Direct
Cu,Zn superoxide dismutase-like0Direct
MIR domain0Direct
Ribosomal proteins S24e, L23 and L15e0Direct
C-terminal, gelsolin-like domain of Sec23/240Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
ISP domain0Direct
Class II aaRS and biotin synthetases0.00000151Direct
RING/U-box0.000002404Direct
SNARE-like0.000004622Direct
Acid proteases0.000006619Direct
Translation proteins0.000007347Direct
PAP/OAS1 substrate-binding domain0.000008339Direct
B-box zinc-binding domain0.00003297Direct
Translation proteins SH3-like domain0.00004304Direct
CCCH zinc finger0.00004553Direct
Cullin repeat-like0.0000561Direct
Heat shock protein 70kD (HSP70), peptide-binding domain0.0000561Direct
Hect, E3 ligase catalytic domain0.0000561Direct
Arginase/deacetylase0.0000561Direct
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.00009975Direct
ARM repeat0.0002184Direct
Cyclophilin-like0.000266Direct
ENTH/VHS domain0.0006247Direct
Sm-like ribonucleoproteins0.0006652Direct
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0.001105Inherited
L30e-like0.001105Inherited
RNA-binding domain, RBD0.001396Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.001437Inherited
beta and beta-prime subunits of DNA dependent RNA-polymerase0.001855Inherited
Sec1/munc18-like (SM) proteins0.001855Inherited
"Winged helix" DNA-binding domain0.002332Inherited
P-loop containing nucleoside triphosphate hydrolases0.002748Inherited
PAZ domain0.002831Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.003128Inherited
Activating enzymes of the ubiquitin-like proteins0.003128Inherited
Riboflavin synthase domain-like0.003128Inherited
FKBP-like0.003763Inherited
Leucine zipper domain0.004608Inherited
4Fe-4S ferredoxins0.005789Inherited
Frizzled cysteine-rich domain0.005789Inherited
Zn-binding ribosomal proteins0.008652Inherited
Single hybrid motif0.00951Inherited
DHS-like NAD/FAD-binding domain0.009607Inherited
Saposin0.0123Inherited
Histone-fold0.01285Inherited
Cyclin-like0.01554Inherited
p53-like transcription factors0.01554Inherited
FYVE/PHD zinc finger0.0158Inherited
ADC-like0.01778Inherited
Integrin domains0.01778Inherited
Cdc48 domain 2-like0.01778Inherited
SET domain0.01803Inherited
PH domain-like0.02096Inherited
Protein kinase-like (PK-like)0.02611Inherited
SH3-domain0.02819Inherited
Homeodomain-like0.03023Inherited
UBC-like0.03234Inherited
PDZ domain-like0.03596Inherited
Actin-like ATPase domain0.04246Inherited
Chaperone J-domain0.04246Inherited
dsRNA-binding domain-like0.04851Inherited
HLH, helix-loop-helix DNA-binding domain0.0486Inherited
ARID-like0.05956Inherited
CAD & PB1 domains0.05956Inherited
Tubby C-terminal domain-like0.05956Inherited
S15/NS1 RNA-binding domain0.05956Inherited
Quinoprotein alcohol dehydrogenase-like0.05975Inherited
Cysteine-rich domain0.07286Inherited
HSP20-like chaperones0.08303Inherited
Nucleic acid-binding proteins0.09614Inherited
Cysteine proteinases0.1025Inherited
KA1-like0.1241Inherited
GTPase activation domain, GAP0.138Inherited
SH2 domain0.2077Inherited
Nucleotidyltransferase0.208Inherited
Transducin (alpha subunit), insertion domain0.2366Inherited
HMG-box0.2685Inherited
Eukaryotic type KH-domain (KH-domain type I)0.285Inherited
Second domain of FERM0.3313Inherited
Nucleotidylyl transferase0.3591Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.3846Inherited
Intermediate filament protein, coiled coil region0.4403Inherited
C2 domain (Calcium/lipid-binding domain, CaLB)0.4734Inherited
Spectrin repeat0.4961Inherited
PYP-like sensor domain (PAS domain)0.4961Inherited
Lamin A/C globular tail domain0.4961Inherited
Chromo domain-like0.5245Inherited
FAD/NAD-linked reductases, dimerisation (C-terminal) domain0.5608Inherited
Ribonuclease H-like0.6208Inherited
Nuclear receptor ligand-binding domain0.8069Inherited
Clavaminate synthase-like0.9324Inherited
ClpP/crotonase1Inherited


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Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Clathrin coat assembly domain0Direct
POU-specific domain0Direct
Cullin repeat0Direct
Trunk domain of Sec23/240Direct
Epsilon subunit of mitochondrial F1F0-ATP synthase0Direct
Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta0Direct
Acyl-carrier protein (ACP)0Direct
beta-sandwich domain of Sec23/240Direct
RecA protein-like (ATPase-domain)0Direct
Brix domain0Direct
ValRS/IleRS/LeuRS editing domain0Direct
Ribosomal protein L10Direct
Helical domain of Sec23/240Direct
Sir2 family of transcriptional regulators0Direct
F1F0 ATP synthase subunit C0Direct
SMAD MH1 domain0Direct
Quinoprotein alcohol dehydrogenase-like0Direct
14-3-3 protein0Direct
Hsp90 middle domain0Direct
Heat shock protein 90, HSP90, N-terminal domain0Direct
Nop domain0Direct
Heat shock protein 70kD (HSP70), C-terminal subdomain0Direct
a tRNA synthase domain0Direct
RNA editing terminal uridyl transferase 2, RET2, domain 20Direct
Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain0Direct
Group II chaperonin (CCT, TRIC), ATPase domain0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Phoshoinositide 3-kinase (PI3K) helical domain0Direct
HSP200Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
PDI-like0Direct
Ubiquitin carboxyl-terminal hydrolase UCH-L0Direct
Histone deacetylase, HDAC0Direct
Erythroid transcription factor GATA-10Direct
Integrin domains0Direct
HSP90 C-terminal domain0Direct
Group II chaperonin (CCT, TRIC), intermediate domain0Direct
Proteasome subunits0Direct
Heme-dependent catalases0Direct
Tubulin, C-terminal domain0Direct
Group II chaperonin (CCT, TRIC), apical domain0Direct
Adenain-like0Direct
Phoshoinositide 3-kinase (PI3K), catalytic domain0Direct
Cullin homology domain0Direct
ets domain0Direct
RNA-polymerase beta0Direct
Anticodon-binding domain of Class II aaRS0Direct
C-terminal, gelsolin-like domain of Sec23/240Direct
p120GAP domain-like0Direct
S-adenosylmethionine synthetase0Direct
MIR domain0Direct
Inositol polyphosphate 5-phosphatase (IPP5)0Direct
Mammalian PLC0Direct
Clathrin adaptor core protein0Direct
FF domain0Direct
CAT-like0Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0Direct
Tubulin, GTPase domain0Direct
SCF ubiquitin ligase complex WHB domain0Direct
MIF4G domain-like0Direct
L30e/L7ae ribosomal proteins0Direct
Cu,Zn superoxide dismutase-like0Direct
Zn-finger domain of Sec23/240Direct
Actin/HSP700.000000001659Direct
UBC-related0.0000000307Direct
Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain0.0000006282Direct
Pepsin-like0.0000006282Direct
Dual specificity phosphatase-like0.000001662Direct
Ubiquitin carboxyl-terminal hydrolase, UCH0.000001945Direct
Papain-like0.00002357Direct
Class I aminoacyl-tRNA synthetases (RS), catalytic domain0.00009396Direct
Hect, E3 ligase catalytic domain0.0001963Direct
Armadillo repeat0.0001976Direct
B-box zinc-binding domain0.0002182Direct
CCCH zinc finger0.0004836Direct
Translational machinery components0.0005375Direct
Heat shock protein 70kD (HSP70), peptide-binding domain0.0005375Direct
SMAD domain0.0005375Direct
Cyclophilin (peptidylprolyl isomerase)0.00137Inherited
PDZ domain0.001811Inherited
TBP-associated factors, TAFs0.001925Inherited
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0.00307Inherited
Histone lysine methyltransferases0.003212Inherited
Canonical RBD0.005191Inherited
Sm motif of small nuclear ribonucleoproteins, SNRNP0.005401Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.009899Inherited
FKBP immunophilin/proline isomerase0.009899Inherited
Frizzled cysteine-rich domain0.01061Inherited
EF-hand modules in multidomain proteins0.01061Inherited
Ubiquitin activating enzymes (UBA)0.01061Inherited
Transforming growth factor (TGF)-beta0.01061Inherited
Extended PAW domain0.01264Inherited
Elongation factors0.01264Inherited
PAZ domain0.01737Inherited
Homeodomain0.01879Inherited
Leucine zipper domain0.01998Inherited
Cold shock DNA-binding domain-like0.01998Inherited
Biotinyl/lipoyl-carrier proteins and domains0.02367Inherited
Pumilio repeat0.02367Inherited
RING finger domain, C3HC40.02393Inherited
Cdc48 N-terminal domain-like0.02824Inherited
Cdc48 domain 2-like0.02824Inherited
Anticodon-binding domain0.02824Inherited
Nucleosome core histones0.03547Inherited
Cyclin0.03975Inherited
Chaperone J-domain0.04105Inherited
SH3-domain0.0439Inherited
HLH, helix-loop-helix DNA-binding domain0.04694Inherited
PHD domain0.05697Inherited
DEP domain0.0918Inherited
G proteins0.1092Inherited
Calmodulin-like0.1341Inherited
Pleckstrin-homology domain (PH domain)0.1468Inherited
Protein kinase cysteine-rich domain (cys2, phorbol-binding domain)0.1552Inherited
First domain of FERM0.1854Inherited
Extended AAA-ATPase domain0.2211Inherited
Transducin (alpha subunit), insertion domain0.2288Inherited
PLC-like (P variant)0.3349Inherited
Third domain of FERM0.3587Inherited
Intermediate filament protein, coiled coil region0.4297Inherited
Second domain of FERM0.4349Inherited
Synaptotagmin-like (S variant)0.4349Inherited
Protein kinases, catalytic subunit0.4512Inherited
LIM domain0.4841Inherited
N-acetyl transferase, NAT0.5136Inherited
Lamin A/C globular tail domain0.5485Inherited
Spectrin repeat0.5485Inherited
SH2 domain0.5593Inherited
Ubiquitin-related0.5752Inherited
Double-stranded RNA-binding domain (dsRBD)0.6239Inherited
Nuclear receptor1Inherited
Nuclear receptor ligand-binding domain1Inherited


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Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
GroEL equatorial domain-like0Direct
Cu,Zn superoxide dismutase-like0Direct
Heat shock protein 70kD (HSP70), C-terminal subdomain0Direct
MIR domain0Direct
Ribosomal protein L10Direct
Zn-finger domain of Sec23/240Direct
Class II aaRS ABD-related0Direct
ValRS/IleRS/LeuRS editing domain0Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0Direct
Epsilon subunit of mitochondrial F1F0-ATP synthase0Direct
TK C-terminal domain-like0Direct
Tubulin nucleotide-binding domain-like0Direct
Helical domain of Sec23/240Direct
Cullin homology domain0Direct
Subdomain of clathrin and coatomer appendage domain0Direct
Tubulin C-terminal domain-like0Direct
14-3-3 protein0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
GroEL-intermediate domain like0Direct
S-adenosylmethionine synthetase0Direct
Ribosomal proteins S24e, L23 and L15e0Direct
Clathrin adaptor appendage domain0Direct
Ribosomal protein L10-like0Direct
FF domain0Direct
F1F0 ATP synthase subunit C0Direct
Nop domain0Direct
Cytochrome c0Direct
GroEL apical domain-like0Direct
JAB1/MPN domain0Direct
SMAD MH1 domain0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
C-terminal, gelsolin-like domain of Sec23/240Direct
HSP90 C-terminal domain0Direct
Heme-dependent catalase-like0Direct
ISP domain0Direct
Class II aaRS and biotin synthetases0.000001214Direct
RING/U-box0.000001936Direct
SNARE-like0.000003727Direct
Acid proteases0.000005342Direct
Translation proteins0.00000593Direct
PAP/OAS1 substrate-binding domain0.000006734Direct
B-box zinc-binding domain0.00002675Direct
Translation proteins SH3-like domain0.00003499Direct
CCCH zinc finger0.00003702Direct
Hect, E3 ligase catalytic domain0.00004563Direct
Heat shock protein 70kD (HSP70), peptide-binding domain0.00004563Direct
Arginase/deacetylase0.00004563Direct
Cullin repeat-like0.00004563Direct
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.00008132Direct
ARM repeat0.0001784Direct
Cyclophilin-like0.0002178Direct
ENTH/VHS domain0.0005141Direct
Sm-like ribonucleoproteins0.0005484Direct
L30e-like0.0009146Direct
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0.0009146Direct
RNA-binding domain, RBD0.001158Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.001193Inherited
Sec1/munc18-like (SM) proteins0.001543Inherited
beta and beta-prime subunits of DNA dependent RNA-polymerase0.001543Inherited
"Winged helix" DNA-binding domain0.001949Inherited
P-loop containing nucleoside triphosphate hydrolases0.002302Inherited
PAZ domain0.002372Inherited
Activating enzymes of the ubiquitin-like proteins0.002627Inherited
Riboflavin synthase domain-like0.002627Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.002627Inherited
FKBP-like0.003167Inherited
Leucine zipper domain0.003887Inherited
4Fe-4S ferredoxins0.004895Inherited
Frizzled cysteine-rich domain0.004895Inherited
Zn-binding ribosomal proteins0.007368Inherited
Single hybrid motif0.008109Inherited
DHS-like NAD/FAD-binding domain0.008191Inherited
Saposin0.01054Inherited
Histone-fold0.01102Inherited
p53-like transcription factors0.01336Inherited
Cyclin-like0.01336Inherited
FYVE/PHD zinc finger0.0136Inherited
Cdc48 domain 2-like0.01533Inherited
ADC-like0.01533Inherited
Integrin domains0.01533Inherited
SET domain0.01555Inherited
PH domain-like0.01816Inherited
Protein kinase-like (PK-like)0.02274Inherited
SH3-domain0.0246Inherited
Homeodomain-like0.02641Inherited
UBC-like0.02829Inherited
PDZ domain-like0.03152Inherited
Chaperone J-domain0.03731Inherited
Actin-like ATPase domain0.03731Inherited
dsRNA-binding domain-like0.04281Inherited
HLH, helix-loop-helix DNA-binding domain0.04289Inherited
S15/NS1 RNA-binding domain0.05283Inherited
Tubby C-terminal domain-like0.05283Inherited
CAD & PB1 domains0.05283Inherited
ARID-like0.05283Inherited
Quinoprotein alcohol dehydrogenase-like0.053Inherited
Cysteine-rich domain0.06498Inherited
HSP20-like chaperones0.07433Inherited
Ribosomal protein S5 domain 2-like0.08521Inherited
Nucleic acid-binding proteins0.08648Inherited
Cysteine proteinases0.09238Inherited
KA1-like0.1125Inherited
GTPase activation domain, GAP0.1255Inherited
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.1513Inherited
SH2 domain0.1911Inherited
Nucleotidyltransferase0.1914Inherited
Transducin (alpha subunit), insertion domain0.2189Inherited
HMG-box0.2497Inherited
Calponin-homology domain, CH-domain0.2497Inherited
Eukaryotic type KH-domain (KH-domain type I)0.2657Inherited
Second domain of FERM0.3112Inherited
Nucleotidylyl transferase0.3385Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.3636Inherited
Intermediate filament protein, coiled coil region0.4181Inherited
C2 domain (Calcium/lipid-binding domain, CaLB)0.4516Inherited
Lamin A/C globular tail domain0.4741Inherited
Spectrin repeat0.4741Inherited
PYP-like sensor domain (PAS domain)0.4741Inherited
cAMP-binding domain-like0.4741Inherited
Chromo domain-like0.5019Inherited
FAD/NAD-linked reductases, dimerisation (C-terminal) domain0.5383Inherited
Ribonuclease H-like0.5986Inherited
Lipovitellin-phosvitin complex, superhelical domain0.6061Inherited
Thiamin diphosphate-binding fold (THDP-binding)0.6061Inherited
Lipovitellin-phosvitin complex; beta-sheet shell regions0.6061Inherited
Nuclear receptor ligand-binding domain0.7891Inherited
Clavaminate synthase-like0.9194Inherited
ClpP/crotonase1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
51695,49562
  • 51695 - PLC-like phosphodiesterases
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0Direct
    48592,54849
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 0Direct
    54495,46934
  • 54495 - UBC-like
  • 46934 - UBA-like
  • 0Direct
    50692,54585
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 0Direct
    57756,57756
  • 57756 - Retrovirus zinc finger-like domains
  • 57756 - Retrovirus zinc finger-like domains
  • 0Direct
    57863,48403
  • 57863 - ArfGap/RecO-like zinc finger
  • 48403 - Ankyrin repeat
  • 0Direct
    64356,49447
  • 64356 - SNARE-like
  • 49447 - Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor
  • 0Direct
    52518,52922
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 52922 - TK C-terminal domain-like
  • 0Direct
    50729,56112
  • 50729 - PH domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    54849,52029
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0Direct
    81698,81698
  • 81698 - FF domain
  • 81698 - FF domain
  • 0Direct
    55785,55785
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0Direct
    47473,51695
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 0Direct
    81333,81333
  • 81333 - F1F0 ATP synthase subunit C
  • 81333 - F1F0 ATP synthase subunit C
  • 0Direct
    49562,48371
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 0Direct
    55973,55973
  • 55973 - S-adenosylmethionine synthetase
  • 55973 - S-adenosylmethionine synthetase
  • 0Direct
    49348,55711
  • 49348 - Clathrin adaptor appendage domain
  • 55711 - Subdomain of clathrin and coatomer appendage domain
  • 0Direct
    55681,52954
  • 55681 - Class II aaRS and biotin synthetases
  • 52954 - Class II aaRS ABD-related
  • 0Direct
    54534,54534
  • 54534 - FKBP-like
  • 54534 - FKBP-like
  • 0Direct
    81811,82754
  • 81811 - Helical domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0Direct
    50729,47473
  • 50729 - PH domain-like
  • 47473 - EF-hand
  • 0Direct
    100920,100934
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
  • 0Direct
    82919,53300
  • 82919 - Zn-finger domain of Sec23/24
  • 53300 - vWA-like
  • 0Direct
    46785,46785
  • 46785 - "Winged helix" DNA-binding domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    74788,75632
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 0Direct
    75632,46785
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    52490,55307
  • 52490 - Tubulin nucleotide-binding domain-like
  • 55307 - Tubulin C-terminal domain-like
  • 0Direct
    50677,52374
  • 50677 - ValRS/IleRS/LeuRS editing domain
  • 52374 - Nucleotidylyl transferase
  • 0Direct
    52540,47917
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase
  • 0Direct
    54585,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    81301,81631
  • 81301 - Nucleotidyltransferase
  • 81631 - PAP/OAS1 substrate-binding domain
  • 0.000003727Direct
    53067,100920
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 0.00004563Direct
    47954,47954
  • 47954 - Cyclin-like
  • 47954 - Cyclin-like
  • 0.00005615Direct
    54928,54928
  • 54928 - RNA-binding domain, RBD
  • 54928 - RNA-binding domain, RBD
  • 0.0002142Direct
    48452,48452
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 0.0002142Direct
    101690,53098
  • 101690 - PAZ domain
  • 53098 - Ribonuclease H-like
  • 0.0004809Direct
    50447,50465
  • 50447 - Translation proteins
  • 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
  • 0.0009146Direct
    57889,57889
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 0.0009146Direct
    52540,50447
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 0.001307Inherited
    57850,57845
  • 57850 - RING/U-box
  • 57845 - B-box zinc-binding domain
  • 0.001325Inherited
    51045,51045
  • 51045 - WW domain
  • 51045 - WW domain
  • 0.001543Inherited
    48371,56112
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.004895Inherited
    90229,90229
  • 90229 - CCCH zinc finger
  • 90229 - CCCH zinc finger
  • 0.006038Inherited
    50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0.007368Inherited
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.007368Inherited
    55550,50044
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0.01533Inherited
    63380,52343
  • 63380 - Riboflavin synthase domain-like
  • 52343 - Ferredoxin reductase-like, C-terminal NADP-linked domain
  • 0.02004Inherited
    57850,57850
  • 57850 - RING/U-box
  • 57850 - RING/U-box
  • 0.03131Inherited
    53067,53067
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 0.03731Inherited
    50249,55681
  • 50249 - Nucleic acid-binding proteins
  • 55681 - Class II aaRS and biotin synthetases
  • 0.05283Inherited
    57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.1465Inherited
    47895,52540
  • 47895 - Transducin (alpha subunit), insertion domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.2189Inherited
    47031,50729
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.2384Inherited
    52833,52833
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 0.369Inherited
    54236,47031
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 0.4554Inherited
    64593,74853
  • 64593 - Intermediate filament protein, coiled coil region
  • 74853 - Lamin A/C globular tail domain
  • 0.5383Inherited
    51905,55424
  • 51905 - FAD/NAD(P)-binding domain
  • 55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain
  • 0.5383Inherited
    46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.6061Inherited
    48431,56968
  • 48431 - Lipovitellin-phosvitin complex, superhelical domain
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 0.6061Inherited
    56968,48431
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 48431 - Lipovitellin-phosvitin complex, superhelical domain
  • 0.6061Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.7463Inherited
    57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.9729Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    48592,54849,52029
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0Direct
    50692,54585,52540
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    49562,48371,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    48452,48452,48452
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 0Direct
    48371,48371,48371
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 0Direct
    55973,55973,55973
  • 55973 - S-adenosylmethionine synthetase
  • 55973 - S-adenosylmethionine synthetase
  • 55973 - S-adenosylmethionine synthetase
  • 0Direct
    50729,47473,51695
  • 50729 - PH domain-like
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 0Direct
    54585,52540,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    53067,100920,100934
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
  • 0Direct
    74788,75632,46785
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    53067,53067,100920
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 0.00004563Direct
    52540,50447,50465
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
  • 0.0009146Direct
    57850,57850,57850
  • 57850 - RING/U-box
  • 57850 - RING/U-box
  • 57850 - RING/U-box
  • 0.008191Inherited
    54236,47031,50729
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.3762Inherited
    52833,52833,52833
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 0.4181Inherited
    57716,57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.4181Inherited
    56968,48431,56968
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 48431 - Lipovitellin-phosvitin complex, superhelical domain
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 0.6061Inherited
    46966,46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.6061Inherited
    57424,57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.9729Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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