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Worm Phenotype (WP): gene expression variant

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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)

Shortest distance to current term (+ for parents, - for children) WP term [WP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + 5:   Variant [WBPhenotype:0000886] <2>
+ + + + 4:   physiology variant [WBPhenotype:0000519] <14>(510|587) (510|248|68)
+ + + 3:   organism physiology variant [WBPhenotype:0000576] <9>(369|431) (372|193|56)
+ + 2:   organism homeostasis metabolism variant [WBPhenotype:0000577] <16>(361|421) (363|190|55)
+ 1:   organism metabolism processing variant [WBPhenotype:0000027] <25>(178|190) (182|87|26)
0:   gene expression variant [WBPhenotype:0000717] <11>(127|139) (131|64|20)
- 1:   RNA expression variant [WBPhenotype:0000113] <10>(20|16) (20|5|0)
- 1:   protein expression variant [WBPhenotype:0000112] <6>(39|44) (41|19|6)
- 1:   dosage compensation variant [WBPhenotype:0000718] <3>(1|0) (1|0|0)
- 1:   transgene expression variant [WBPhenotype:0000306] <3>(82|99) (85|43|14)
- 1:   antimicrobial gene expression variant [WBPhenotype:0002534] <2>(8|9) (9|3|1)
- 1:   gene expression level high [WBPhenotype:0000135] <1>(2|2) (2|0|0)
- 1:   gene expression level reduced [WBPhenotype:0000134] <1>(6|3) (6|0|0)
- 1:   pathogen induced gene expression variant [WBPhenotype:0001857] <1>(8|9) (9|3|1)
- 1:   drug induced gene expression variant [WBPhenotype:0001838](5|6) (5|2|0)
- 1:   environmental stimuli induced gene expression variant [WBPhenotype:0001861](0|0) (0|0|0)
- 1:   pattern of gene expression variant [WBPhenotype:0000111](0|0) (0|0|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Heat shock protein 70kD (HSP70), C-terminal subdomain0Direct
F1F0 ATP synthase subunit C0Direct
FF domain0Direct
JAB1/MPN domain0Direct
Ribosomal protein L10-like0Direct
Helical domain of Sec23/240Direct
TK C-terminal domain-like0Direct
Ribosomal proteins S24e, L23 and L15e0Direct
Cytochrome c0Direct
GroEL-intermediate domain like0Direct
GroEL equatorial domain-like0Direct
MIR domain0Direct
C-terminal, gelsolin-like domain of Sec23/240Direct
Sec1/munc18-like (SM) proteins0Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Class II aaRS ABD-related0Direct
Heme-dependent catalase-like0Direct
14-3-3 protein0Direct
Cu,Zn superoxide dismutase-like0Direct
Histone-fold0Direct
Ribosomal protein L10Direct
Zn-finger domain of Sec23/240Direct
S-adenosylmethionine synthetase0Direct
ValRS/IleRS/LeuRS editing domain0Direct
ISP domain0Direct
Nop domain0Direct
SMAD MH1 domain0Direct
Subdomain of clathrin and coatomer appendage domain0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Cullin homology domain0Direct
Clathrin adaptor appendage domain0Direct
Epsilon subunit of mitochondrial F1F0-ATP synthase0Direct
Tubulin C-terminal domain-like0Direct
GroEL apical domain-like0Direct
HSP90 C-terminal domain0Direct
Tubulin nucleotide-binding domain-like0Direct
Chromo domain-like0.0000000003088Direct
FYVE/PHD zinc finger0.0000000157Direct
SET domain0.0000001156Direct
RING/U-box0.000003572Direct
Acid proteases0.000003616Direct
Class II aaRS and biotin synthetases0.000003616Direct
Cysteine-rich domain0.000004141Direct
SNARE-like0.000009201Direct
PAP/OAS1 substrate-binding domain0.00001716Direct
Translation proteins0.00001827Direct
Bromodomain0.00004687Direct
Translation proteins SH3-like domain0.0000765Direct
Arginase/deacetylase0.00009084Direct
Heat shock protein 70kD (HSP70), peptide-binding domain0.00009084Direct
Cullin repeat-like0.00009084Direct
Hect, E3 ligase catalytic domain0.00009084Direct
CCCH zinc finger0.000108Direct
B-box zinc-binding domain0.0002035Direct
ARM repeat0.000212Direct
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.0002303Direct
Retrovirus zinc finger-like domains0.0004275Direct
Cyclophilin-like0.0004898Direct
ACP-like0.0008423Direct
Sm-like ribonucleoproteins0.001202Inherited
RNA-binding domain, RBD0.001274Inherited
"Winged helix" DNA-binding domain0.001274Inherited
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0.001648Inherited
L30e-like0.001648Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.002209Inherited
beta and beta-prime subunits of DNA dependent RNA-polymerase0.002521Inherited
Tudor/PWWP/MBT0.002672Inherited
Riboflavin synthase domain-like0.004408Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.004408Inherited
PAZ domain0.005399Inherited
FKBP-like0.005477Inherited
P-loop containing nucleoside triphosphate hydrolases0.005795Inherited
4Fe-4S ferredoxins0.007446Inherited
Frizzled cysteine-rich domain0.007446Inherited
Leucine zipper domain0.007976Inherited
Cyclin-like0.009852Inherited
Zn-binding ribosomal proteins0.01148Inherited
dsRNA-binding domain-like0.01218Inherited
DHS-like NAD/FAD-binding domain0.01317Inherited
Single hybrid motif0.01347Inherited
Saposin0.02037Inherited
ADC-like0.02161Inherited
Cdc48 domain 2-like0.02161Inherited
Integrin domains0.02161Inherited
HIT/MYND zinc finger-like0.02482Inherited
p53-like transcription factors0.02593Inherited
PH domain-like0.02618Inherited
PX domain0.02745Inherited
Homeodomain-like0.0317Inherited
SH3-domain0.03197Inherited
UBC-like0.03648Inherited
Chaperone J-domain0.04743Inherited
Actin-like ATPase domain0.04743Inherited
HLH, helix-loop-helix DNA-binding domain0.05402Inherited
PDZ domain-like0.06917Inherited
ARID-like0.0712Inherited
Tubby C-terminal domain-like0.0712Inherited
S15/NS1 RNA-binding domain0.0712Inherited
CAD & PB1 domains0.0712Inherited
Protein kinase-like (PK-like)0.07575Inherited
Quinoprotein alcohol dehydrogenase-like0.08343Inherited
Nucleic acid-binding proteins0.08688Inherited
HSP20-like chaperones0.09065Inherited
SAM/Pointed domain0.1439Inherited
KA1-like0.1456Inherited
Cysteine proteinases0.1508Inherited
GTPase activation domain, GAP0.1917Inherited
Nucleotidyltransferase0.2195Inherited
Eukaryotic type KH-domain (KH-domain type I)0.2479Inherited
Transducin (alpha subunit), insertion domain0.2479Inherited
HMG-box0.2479Inherited
WD40 repeat-like0.2609Inherited
SH2 domain0.2778Inherited
Second domain of FERM0.3916Inherited
Nucleotidylyl transferase0.4104Inherited
Intermediate filament protein, coiled coil region0.4502Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.4532Inherited
C2 domain (Calcium/lipid-binding domain, CaLB)0.4942Inherited
Spectrin repeat0.5042Inherited
Activating enzymes of the ubiquitin-like proteins0.5042Inherited
PYP-like sensor domain (PAS domain)0.5042Inherited
Lamin A/C globular tail domain0.5042Inherited
Ribonuclease H-like0.5967Inherited
Clavaminate synthase-like0.6951Inherited
Nuclear receptor ligand-binding domain0.9407Inherited
ClpP/crotonase1Inherited


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Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
POU-specific domain0Direct
PDI-like0Direct
CAT-like0Direct
RNA editing terminal uridyl transferase 2, RET2, domain 20Direct
MIR domain0Direct
Ribosomal protein L10Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0Direct
Nop domain0Direct
beta-sandwich domain of Sec23/240Direct
a tRNA synthase domain0Direct
Sir2 family of transcriptional regulators0Direct
Heat shock protein 90, HSP90, N-terminal domain0Direct
ValRS/IleRS/LeuRS editing domain0Direct
Inositol polyphosphate 5-phosphatase (IPP5)0Direct
Brix domain0Direct
Heme-dependent catalases0Direct
Epsilon subunit of mitochondrial F1F0-ATP synthase0Direct
FF domain0Direct
Cullin repeat0Direct
Hsp90 middle domain0Direct
Tubulin, GTPase domain0Direct
Cu,Zn superoxide dismutase-like0Direct
Quinoprotein alcohol dehydrogenase-like0Direct
Helical domain of Sec23/240Direct
L30e/L7ae ribosomal proteins0Direct
Smc hinge domain0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Acyl-carrier protein (ACP)0Direct
Group II chaperonin (CCT, TRIC), apical domain0Direct
Sec1/munc18-like (SM) proteins0Direct
Zn-finger domain of Sec23/240Direct
SCF ubiquitin ligase complex WHB domain0Direct
HSP200Direct
Group II chaperonin (CCT, TRIC), intermediate domain0Direct
Phoshoinositide 3-kinase (PI3K), catalytic domain0Direct
Ubiquitin carboxyl-terminal hydrolase UCH-L0Direct
Clathrin adaptor core protein0Direct
Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain0Direct
RNA-polymerase beta0Direct
14-3-3 protein0Direct
p120GAP domain-like0Direct
Proteasome subunits0Direct
Phoshoinositide 3-kinase (PI3K) helical domain0Direct
Histone deacetylase, HDAC0Direct
Clathrin coat assembly domain0Direct
Erythroid transcription factor GATA-10Direct
Mammalian PLC0Direct
Chromo domain0Direct
Cullin homology domain0Direct
Trunk domain of Sec23/240Direct
Adenain-like0Direct
SMAD MH1 domain0Direct
HSP90 C-terminal domain0Direct
Group II chaperonin (CCT, TRIC), ATPase domain0Direct
F1F0 ATP synthase subunit C0Direct
MIF4G domain-like0Direct
Integrin domains0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
ets domain0Direct
S-adenosylmethionine synthetase0Direct
Tubulin, C-terminal domain0Direct
Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta0Direct
RecA protein-like (ATPase-domain)0Direct
Heat shock protein 70kD (HSP70), C-terminal subdomain0Direct
Anticodon-binding domain of Class II aaRS0Direct
C-terminal, gelsolin-like domain of Sec23/240Direct
Nucleosome core histones0.000000000000003129Direct
Actin/HSP700.000000004572Direct
UBC-related0.00000008393Direct
Forkhead DNA-binding domain0.000000307Direct
Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain0.0000013Direct
PHD domain0.000001336Direct
Dual specificity phosphatase-like0.000003282Direct
Pepsin-like0.000003282Direct
Histone lysine methyltransferases0.00004426Direct
Papain-like0.00005275Direct
Ubiquitin carboxyl-terminal hydrolase, UCH0.00006882Direct
Class I aminoacyl-tRNA synthetases (RS), catalytic domain0.0001677Direct
Bromodomain0.0002415Direct
Hect, E3 ligase catalytic domain0.0002854Direct
Protein kinase cysteine-rich domain (cys2, phorbol-binding domain)0.0003044Direct
Armadillo repeat0.0003073Direct
SMAD domain0.0007469Direct
Translational machinery components0.0007469Direct
Heat shock protein 70kD (HSP70), peptide-binding domain0.0007469Direct
CCCH zinc finger0.0009152Direct
B-box zinc-binding domain0.001056Inherited
Cyclophilin (peptidylprolyl isomerase)0.002184Inherited
TBP-associated factors, TAFs0.002801Inherited
Cold shock DNA-binding domain-like0.003045Inherited
Canonical RBD0.004154Inherited
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0.004183Inherited
PDZ domain0.00568Inherited
Sm motif of small nuclear ribonucleoproteins, SNRNP0.007675Inherited
Extended PAW domain0.008803Inherited
Ubiquitin activating enzymes (UBA)0.0129Inherited
Transforming growth factor (TGF)-beta0.0129Inherited
Frizzled cysteine-rich domain0.0129Inherited
EF-hand modules in multidomain proteins0.0129Inherited
Pumilio repeat0.01318Inherited
FKBP immunophilin/proline isomerase0.01318Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.01318Inherited
Cyclin0.01836Inherited
Elongation factors0.01836Inherited
Homeodomain0.01914Inherited
RING finger domain, C3HC40.02256Inherited
PAZ domain0.027Inherited
Leucine zipper domain0.02978Inherited
Biotinyl/lipoyl-carrier proteins and domains0.03099Inherited
Cdc48 domain 2-like0.03294Inherited
Anticodon-binding domain0.03294Inherited
Biotin dependent carboxylase carboxyltransferase domain0.03294Inherited
Cdc48 N-terminal domain-like0.03294Inherited
Chaperone J-domain0.04377Inherited
HLH, helix-loop-helix DNA-binding domain0.0499Inherited
PX domain0.0599Inherited
SH3-domain0.07594Inherited
DEP domain0.1049Inherited
WD40-repeat0.1098Inherited
Pleckstrin-homology domain (PH domain)0.1541Inherited
G proteins0.2042Inherited
First domain of FERM0.2083Inherited
Extended AAA-ATPase domain0.2296Inherited
Transducin (alpha subunit), insertion domain0.2338Inherited
PLC-like (P variant)0.3399Inherited
N-acetyl transferase, NAT0.3671Inherited
Third domain of FERM0.3973Inherited
Double-stranded RNA-binding domain (dsRBD)0.3973Inherited
Intermediate filament protein, coiled coil region0.4335Inherited
Second domain of FERM0.4868Inherited
Synaptotagmin-like (S variant)0.4868Inherited
LIM domain0.4869Inherited
Protein kinases, catalytic subunit0.5371Inherited
Spectrin repeat0.5467Inherited
Lamin A/C globular tail domain0.5467Inherited
Ubiquitin-related0.5836Inherited
SH2 domain0.6303Inherited
Nuclear receptor1Inherited
Nuclear receptor ligand-binding domain1Inherited


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Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Ribosomal protein L10-like0Direct
F1F0 ATP synthase subunit C0Direct
GroEL equatorial domain-like0Direct
Epsilon subunit of mitochondrial F1F0-ATP synthase0Direct
ValRS/IleRS/LeuRS editing domain0Direct
Clathrin adaptor appendage domain0Direct
Cullin homology domain0Direct
Heme-dependent catalase-like0Direct
C-terminal, gelsolin-like domain of Sec23/240Direct
14-3-3 protein0Direct
S-adenosylmethionine synthetase0Direct
Ribosomal proteins S24e, L23 and L15e0Direct
Tubulin C-terminal domain-like0Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0Direct
Heat shock protein 70kD (HSP70), C-terminal subdomain0Direct
SMAD MH1 domain0Direct
HSP90 C-terminal domain0Direct
JAB1/MPN domain0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
GroEL apical domain-like0Direct
Class II aaRS ABD-related0Direct
Tubulin nucleotide-binding domain-like0Direct
Ribosomal protein L10Direct
GroEL-intermediate domain like0Direct
Subdomain of clathrin and coatomer appendage domain0Direct
Helical domain of Sec23/240Direct
FF domain0Direct
Sec1/munc18-like (SM) proteins0Direct
Nop domain0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
ISP domain0Direct
Cytochrome c0Direct
MIR domain0Direct
TK C-terminal domain-like0Direct
Zn-finger domain of Sec23/240Direct
Histone-fold0Direct
Cu,Zn superoxide dismutase-like0Direct
Chromo domain-like0.0000000002448Direct
FYVE/PHD zinc finger0.00000001252Direct
SET domain0.00000009259Direct
RING/U-box0.0000029Direct
Class II aaRS and biotin synthetases0.000002937Direct
Acid proteases0.000002937Direct
Cysteine-rich domain0.000003364Direct
SNARE-like0.000007486Direct
PAP/OAS1 substrate-binding domain0.00001398Direct
Translation proteins0.0000149Direct
Bromodomain0.00003832Direct
Translation proteins SH3-like domain0.0000626Direct
Hect, E3 ligase catalytic domain0.00007442Direct
Heat shock protein 70kD (HSP70), peptide-binding domain0.00007442Direct
Cullin repeat-like0.00007442Direct
Arginase/deacetylase0.00007442Direct
CCCH zinc finger0.0000885Direct
B-box zinc-binding domain0.0001671Direct
ARM repeat0.0001742Direct
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.0001894Direct
Retrovirus zinc finger-like domains0.0003531Direct
Cyclophilin-like0.0004054Direct
ACP-like0.0007007Direct
ENTH/VHS domain0.000879Direct
Sm-like ribonucleoproteins0.001002Inherited
RNA-binding domain, RBD0.001063Inherited
"Winged helix" DNA-binding domain0.001063Inherited
L30e-like0.001378Inherited
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0.001378Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.001856Inherited
beta and beta-prime subunits of DNA dependent RNA-polymerase0.002123Inherited
Tudor/PWWP/MBT0.002252Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.003738Inherited
Riboflavin synthase domain-like0.003738Inherited
PAZ domain0.00459Inherited
FKBP-like0.004657Inherited
P-loop containing nucleoside triphosphate hydrolases0.004933Inherited
4Fe-4S ferredoxins0.00636Inherited
Frizzled cysteine-rich domain0.00636Inherited
Leucine zipper domain0.006825Inherited
Cyclin-like0.008468Inherited
Zn-binding ribosomal proteins0.009892Inherited
dsRNA-binding domain-like0.01051Inherited
DHS-like NAD/FAD-binding domain0.01138Inherited
Single hybrid motif0.01165Inherited
Saposin0.01773Inherited
Cdc48 domain 2-like0.01883Inherited
Integrin domains0.01883Inherited
ADC-like0.01883Inherited
HIT/MYND zinc finger-like0.0217Inherited
p53-like transcription factors0.02269Inherited
PH domain-like0.02291Inherited
PX domain0.02405Inherited
Homeodomain-like0.02786Inherited
SH3-domain0.0281Inherited
UBC-like0.03213Inherited
Chaperone J-domain0.04197Inherited
Actin-like ATPase domain0.04197Inherited
HLH, helix-loop-helix DNA-binding domain0.04797Inherited
PDZ domain-like0.06179Inherited
Tubby C-terminal domain-like0.06366Inherited
CAD & PB1 domains0.06366Inherited
ARID-like0.06366Inherited
S15/NS1 RNA-binding domain0.06366Inherited
Protein kinase-like (PK-like)0.06784Inherited
Quinoprotein alcohol dehydrogenase-like0.07495Inherited
Nucleic acid-binding proteins0.0781Inherited
HSP20-like chaperones0.08159Inherited
DNase I-like0.1262Inherited
PLC-like phosphodiesterases0.1262Inherited
SAM/Pointed domain0.1312Inherited
KA1-like0.1327Inherited
Cysteine proteinases0.1375Inherited
GTPase activation domain, GAP0.1763Inherited
Nucleotidyltransferase0.2029Inherited
HMG-box0.2302Inherited
Eukaryotic type KH-domain (KH-domain type I)0.2302Inherited
Transducin (alpha subunit), insertion domain0.2302Inherited
WD40 repeat-like0.2429Inherited
SH2 domain0.2593Inherited
Second domain of FERM0.3711Inherited
Nucleotidylyl transferase0.3897Inherited
Intermediate filament protein, coiled coil region0.4293Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.4322Inherited
C2 domain (Calcium/lipid-binding domain, CaLB)0.4725Inherited
Lamin A/C globular tail domain0.4823Inherited
PYP-like sensor domain (PAS domain)0.4823Inherited
Activating enzymes of the ubiquitin-like proteins0.4823Inherited
Spectrin repeat0.4823Inherited
FAD/NAD-linked reductases, dimerisation (C-terminal) domain0.5464Inherited
Ribonuclease H-like0.5748Inherited
Clavaminate synthase-like0.6743Inherited
Nuclear receptor ligand-binding domain0.9271Inherited
ClpP/crotonase1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
47473,51695
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 0Direct
    50677,52374
  • 50677 - ValRS/IleRS/LeuRS editing domain
  • 52374 - Nucleotidylyl transferase
  • 0Direct
    48592,54849
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 0Direct
    50729,56112
  • 50729 - PH domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    81333,81333
  • 81333 - F1F0 ATP synthase subunit C
  • 81333 - F1F0 ATP synthase subunit C
  • 0Direct
    54495,46934
  • 54495 - UBC-like
  • 46934 - UBA-like
  • 0Direct
    81811,82754
  • 81811 - Helical domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0Direct
    100920,100934
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
  • 0Direct
    144232,82199
  • 144232 - HIT/MYND zinc finger-like
  • 82199 - SET domain
  • 0Direct
    50729,47473
  • 50729 - PH domain-like
  • 47473 - EF-hand
  • 0Direct
    54849,52029
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0Direct
    52518,52922
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 52922 - TK C-terminal domain-like
  • 0Direct
    52540,47917
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase
  • 0Direct
    49562,48371
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 0Direct
    74788,75632
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 0Direct
    54534,54534
  • 54534 - FKBP-like
  • 54534 - FKBP-like
  • 0Direct
    55681,52954
  • 55681 - Class II aaRS and biotin synthetases
  • 52954 - Class II aaRS ABD-related
  • 0Direct
    57756,57756
  • 57756 - Retrovirus zinc finger-like domains
  • 57756 - Retrovirus zinc finger-like domains
  • 0Direct
    81698,81698
  • 81698 - FF domain
  • 81698 - FF domain
  • 0Direct
    55973,55973
  • 55973 - S-adenosylmethionine synthetase
  • 55973 - S-adenosylmethionine synthetase
  • 0Direct
    55785,55785
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0Direct
    57903,51197
  • 57903 - FYVE/PHD zinc finger
  • 51197 - Clavaminate synthase-like
  • 0Direct
    54585,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    55729,55729
  • 55729 - Acyl-CoA N-acyltransferases (Nat)
  • 55729 - Acyl-CoA N-acyltransferases (Nat)
  • 0Direct
    54160,54160
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 0Direct
    57903,82199
  • 57903 - FYVE/PHD zinc finger
  • 82199 - SET domain
  • 0Direct
    46785,46785
  • 46785 - "Winged helix" DNA-binding domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    75632,46785
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    51695,49562
  • 51695 - PLC-like phosphodiesterases
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0Direct
    50692,54585
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 0Direct
    82919,53300
  • 82919 - Zn-finger domain of Sec23/24
  • 53300 - vWA-like
  • 0Direct
    64356,49447
  • 64356 - SNARE-like
  • 49447 - Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor
  • 0Direct
    57863,48403
  • 57863 - ArfGap/RecO-like zinc finger
  • 48403 - Ankyrin repeat
  • 0Direct
    54160,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    52490,55307
  • 52490 - Tubulin nucleotide-binding domain-like
  • 55307 - Tubulin C-terminal domain-like
  • 0Direct
    49348,55711
  • 49348 - Clathrin adaptor appendage domain
  • 55711 - Subdomain of clathrin and coatomer appendage domain
  • 0Direct
    81301,81631
  • 81301 - Nucleotidyltransferase
  • 81631 - PAP/OAS1 substrate-binding domain
  • 0.000007486Direct
    47954,47954
  • 47954 - Cyclin-like
  • 47954 - Cyclin-like
  • 0.000007486Direct
    53067,100920
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 0.00007442Direct
    54928,54928
  • 54928 - RNA-binding domain, RBD
  • 54928 - RNA-binding domain, RBD
  • 0.00007779Direct
    48452,48452
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 0.0004404Direct
    101690,53098
  • 101690 - PAZ domain
  • 53098 - Ribonuclease H-like
  • 0.0007007Direct
    50447,50465
  • 50447 - Translation proteins
  • 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
  • 0.001378Inherited
    57889,57889
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 0.001378Inherited
    51045,51045
  • 51045 - WW domain
  • 51045 - WW domain
  • 0.002123Inherited
    52540,50447
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 0.002253Inherited
    57850,57845
  • 57850 - RING/U-box
  • 57845 - B-box zinc-binding domain
  • 0.005095Inherited
    48371,56112
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.00636Inherited
    90229,90229
  • 90229 - CCCH zinc finger
  • 90229 - CCCH zinc finger
  • 0.009601Inherited
    50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0.009892Inherited
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.009892Inherited
    55550,50044
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0.01883Inherited
    53067,53067
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 0.04197Inherited
    57850,57850
  • 57850 - RING/U-box
  • 57850 - RING/U-box
  • 0.04328Inherited
    50249,55681
  • 50249 - Nucleic acid-binding proteins
  • 55681 - Class II aaRS and biotin synthetases
  • 0.06366Inherited
    57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.1568Inherited
    47895,52540
  • 47895 - Transducin (alpha subunit), insertion domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.2302Inherited
    47031,50729
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.2852Inherited
    52833,52833
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 0.3813Inherited
    54236,47031
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 0.5089Inherited
    64593,74853
  • 64593 - Intermediate filament protein, coiled coil region
  • 74853 - Lamin A/C globular tail domain
  • 0.5464Inherited
    51905,55424
  • 51905 - FAD/NAD(P)-binding domain
  • 55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain
  • 0.5464Inherited
    46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.6117Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.7586Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    54160,54160,52540
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    48371,48371,48371
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 0Direct
    48452,48452,48452
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 0Direct
    49562,48371,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    53067,100920,100934
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
  • 0Direct
    50729,47473,51695
  • 50729 - PH domain-like
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 0Direct
    55973,55973,55973
  • 55973 - S-adenosylmethionine synthetase
  • 55973 - S-adenosylmethionine synthetase
  • 55973 - S-adenosylmethionine synthetase
  • 0Direct
    50692,54585,52540
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    54585,52540,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    48592,54849,52029
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0Direct
    74788,75632,46785
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    54160,52540,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    53067,53067,100920
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 0.00007442Direct
    52540,50447,50465
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
  • 0.001378Inherited
    57850,57850,57850
  • 57850 - RING/U-box
  • 57850 - RING/U-box
  • 57850 - RING/U-box
  • 0.01138Inherited
    54236,47031,50729
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.4272Inherited
    52833,52833,52833
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 0.4293Inherited
    57716,57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.4293Inherited
    46966,46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.6117Inherited
    57424,57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.9656Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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