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Worm Phenotype (WP): cell death variant

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Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)

Shortest distance to current term (+ for parents, - for children) WP term [WP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   Variant [WBPhenotype:0000886] <5>
+ + 2:   physiology variant [WBPhenotype:0000519] <6>(490|567) (491|248|69)
+ 1:   cell physiology variant [WBPhenotype:0000536] <27>(143|144) (143|64|18)
0:   cell death variant [WBPhenotype:0000729] <3>(57|51) (58|17|5)
- 1:   programmed cell death variant [WBPhenotype:0001172] <3>(55|48) (56|16|5)
- 1:   induced cell death variant [WBPhenotype:0001268] <2>(1|2) (1|1|0)
- 1:   cell degeneration [WBPhenotype:0000178] <1>(0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Clathrin adaptor appendage domain0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Subdomain of clathrin and coatomer appendage domain0Direct
DLC0Direct
PX domain0Direct
VPS9 domain0Direct
RBP11-like subunits of RNA polymerase0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Calpain large subunit, middle domain (domain III)0.0000004504Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase0.000000771Direct
Cullin repeat-like0.00000184Direct
FYVE/PHD zinc finger0.00000436Direct
Skp1 dimerisation domain-like0.00001504Direct
Integrin domains0.0001136Direct
Terpenoid cyclases/Protein prenyltransferases0.0001136Direct
Cupredoxins0.0005002Direct
Tubby C-terminal domain-like0.0005002Direct
Caspase-like0.0005002Direct
Protein kinase-like (PK-like)0.0008686Direct
Cullin homology domain0.001037Inherited
GroEL apical domain-like0.002063Inherited
GroEL-intermediate domain like0.00536Inherited
GroEL equatorial domain-like0.00536Inherited
ENTH/VHS domain0.006799Inherited
Sm-like ribonucleoproteins0.006799Inherited
SET domain0.007492Inherited
BAR/IMD domain-like0.007492Inherited
Cysteine proteinases0.01371Inherited
Calcium ATPase, transmembrane domain M0.01656Inherited
Metal cation-transporting ATPase, ATP-binding domain N0.01656Inherited
F1F0 ATP synthase subunit C0.02445Inherited
DNA repair protein MutS, domain III0.02445Inherited
5' to 3' exonuclease, C-terminal subdomain0.02445Inherited
Activating enzymes of the ubiquitin-like proteins0.03356Inherited
DEATH domain0.03356Inherited
Calcium ATPase, transduction domain A0.0354Inherited
SH3-domain0.04873Inherited
PH domain-like0.06736Inherited
HLH, helix-loop-helix DNA-binding domain0.07038Inherited
Sec1/munc18-like (SM) proteins0.08012Inherited
Hect, E3 ligase catalytic domain0.08012Inherited
Lamin A/C globular tail domain0.1425Inherited
ARM repeat0.143Inherited
PIN domain-like0.1625Inherited
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.1625Inherited
SNARE-like0.1885Inherited
POZ domain0.1943Inherited
Saposin0.2147Inherited
Intermediate filament protein, coiled coil region0.2624Inherited
Chromo domain-like0.2624Inherited
"Winged helix" DNA-binding domain0.409Inherited
Metallo-dependent phosphatases0.4303Inherited
Nucleic acid-binding proteins0.4807Inherited
Histone-fold0.5666Inherited
WD40 repeat-like0.6288Inherited
S-adenosyl-L-methionine-dependent methyltransferases0.6926Inherited
RNA-binding domain, RBD0.9492Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
DLC0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Cullin repeat0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Protein prenyltransferases0Direct
Phoshoinositide 3-kinase (PI3K) helical domain0Direct
Arginine methyltransferase0Direct
RNA-polymerase beta0Direct
Integrin domains0Direct
SCF ubiquitin ligase complex WHB domain0Direct
Myotubularin-like phosphatases0Direct
PX domain0Direct
Group II chaperonin (CCT, TRIC), intermediate domain0Direct
FYVE, a phosphatidylinositol-3-phosphate binding domain0.000000000000001258Direct
Calpain large subunit, middle domain (domain III)0.000001292Direct
RecA protein-like (ATPase-domain)0.000001848Direct
Skp1 dimerisation domain-like0.00001597Direct
Ephrin ectodomain0.0001861Direct
Caspase catalytic domain0.0001861Direct
Calpain large subunit, catalytic domain (domain II)0.0002926Direct
Group II chaperonin (CCT, TRIC), apical domain0.0003249Direct
Group II chaperonin (CCT, TRIC), ATPase domain0.0009427Direct
Cullin homology domain0.0009427Direct
Phoshoinositide 3-kinase (PI3K), catalytic domain0.001926Inherited
BTB/POZ domain0.008136Inherited
Sm motif of small nuclear ribonucleoproteins, SNRNP0.01267Inherited
Histone lysine methyltransferases0.01505Inherited
Protein kinases, catalytic subunit0.01587Inherited
G proteins0.01665Inherited
BAR domain0.02225Inherited
5' to 3' exonuclease, C-terminal subdomain0.02225Inherited
DNA repair protein MutS, domain III0.02225Inherited
5' to 3' exonuclease catalytic domain0.02225Inherited
Ubiquitin activating enzymes (UBA)0.02225Inherited
F1F0 ATP synthase subunit C0.02225Inherited
Cold shock DNA-binding domain-like0.03015Inherited
Calcium ATPase, transduction domain A0.03399Inherited
SH3-domain0.05085Inherited
HLH, helix-loop-helix DNA-binding domain0.07031Inherited
Clathrin adaptor core protein0.07438Inherited
Sec1/munc18-like (SM) proteins0.07473Inherited
Hect, E3 ligase catalytic domain0.07473Inherited
Phosphotyrosine-binding domain (PTB)0.1203Inherited
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.1551Inherited
Translational machinery components0.2544Inherited
Intermediate filament protein, coiled coil region0.2544Inherited
Armadillo repeat0.3035Inherited
Nucleosome core histones0.5547Inherited
Proteasome subunits0.6561Inherited
ABC transporter ATPase domain-like0.8626Inherited
Canonical RBD0.9467Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
DLC0Direct
Clathrin adaptor appendage domain0Direct
RBP11-like subunits of RNA polymerase0Direct
Subdomain of clathrin and coatomer appendage domain0Direct
PX domain0Direct
VPS9 domain0Direct
Calpain large subunit, middle domain (domain III)0.0000003607Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase0.0000006192Direct
Cullin repeat-like0.000001483Direct
FYVE/PHD zinc finger0.000003519Direct
Skp1 dimerisation domain-like0.00001218Direct
Integrin domains0.00009268Direct
Terpenoid cyclases/Protein prenyltransferases0.00009268Direct
Caspase-like0.0004119Direct
Cupredoxins0.0004119Direct
Tubby C-terminal domain-like0.0004119Direct
Protein kinase-like (PK-like)0.000718Direct
Cullin homology domain0.0008586Direct
GroEL apical domain-like0.001724Inherited
GroEL equatorial domain-like0.004537Inherited
GroEL-intermediate domain like0.004537Inherited
ENTH/VHS domain0.005774Inherited
Sm-like ribonucleoproteins0.005774Inherited
SET domain0.00637Inherited
BAR/IMD domain-like0.00637Inherited
Cysteine proteinases0.01178Inherited
Calcium ATPase, transmembrane domain M0.01429Inherited
Metal cation-transporting ATPase, ATP-binding domain N0.01429Inherited
DNA repair protein MutS, domain III0.02128Inherited
FAD/NAD-linked reductases, dimerisation (C-terminal) domain0.02128Inherited
F1F0 ATP synthase subunit C0.02128Inherited
5' to 3' exonuclease, C-terminal subdomain0.02128Inherited
DEATH domain0.02936Inherited
Activating enzymes of the ubiquitin-like proteins0.02936Inherited
Calcium ATPase, transduction domain A0.031Inherited
SH3-domain0.04297Inherited
PH domain-like0.05987Inherited
HLH, helix-loop-helix DNA-binding domain0.06259Inherited
Hect, E3 ligase catalytic domain0.07153Inherited
Sec1/munc18-like (SM) proteins0.07153Inherited
Lamin A/C globular tail domain0.1296Inherited
ARM repeat0.1301Inherited
PIN domain-like0.1483Inherited
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.1483Inherited
SNARE-like0.1728Inherited
POZ domain0.1782Inherited
Saposin0.1978Inherited
Intermediate filament protein, coiled coil region0.2436Inherited
Chromo domain-like0.2436Inherited
"Winged helix" DNA-binding domain0.3867Inherited
Metallo-dependent phosphatases0.4079Inherited
Nucleic acid-binding proteins0.458Inherited
Histone-fold0.5441Inherited
WD40 repeat-like0.6066Inherited
S-adenosyl-L-methionine-dependent methyltransferases0.6716Inherited
RNA-binding domain, RBD0.9378Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
52540,47917
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase
  • 0Direct
    74788,75632
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 0Direct
    75632,46785
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    49348,55711
  • 49348 - Clathrin adaptor appendage domain
  • 55711 - Subdomain of clathrin and coatomer appendage domain
  • 0Direct
    49562,48371
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 0Direct
    54001,49758
  • 54001 - Cysteine proteinases
  • 49758 - Calpain large subunit, middle domain (domain III)
  • 0.00000004947Direct
    48371,56112
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.000007647Direct
    54695,81382
  • 54695 - POZ domain
  • 81382 - Skp1 dimerisation domain-like
  • 0.00003131Direct
    81333,81333
  • 81333 - F1F0 ATP synthase subunit C
  • 81333 - F1F0 ATP synthase subunit C
  • 0.00009268Direct
    54849,52029
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.004537Inherited
    48592,54849
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 0.004537Inherited
    81660,56784
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 0.01429Inherited
    51905,55424
  • 51905 - FAD/NAD(P)-binding domain
  • 55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain
  • 0.02128Inherited
    48334,52540
  • 48334 - DNA repair protein MutS, domain III
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.02128Inherited
    57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.1483Inherited
    54928,54928
  • 54928 - RNA-binding domain, RBD
  • 54928 - RNA-binding domain, RBD
  • 0.1728Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.3417Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    49562,48371,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    74788,75632,46785
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    48592,54849,52029
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.004537Inherited
    81660,56784,81665
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 81665 - Calcium ATPase, transmembrane domain M
  • 0.01429Inherited
    57424,57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.1483Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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