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Worm Phenotype (WP): cell death variant

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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)

Shortest distance to current term (+ for parents, - for children) WP term [WP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   Variant [WBPhenotype:0000886] <5>
+ + 2:   physiology variant [WBPhenotype:0000519] <6>(495|573) (496|248|69)
+ 1:   cell physiology variant [WBPhenotype:0000536] <27>(145|145) (146|64|18)
0:   cell death variant [WBPhenotype:0000729] <3>(58|51) (59|17|5)
- 1:   programmed cell death variant [WBPhenotype:0001172] <3>(56|48) (57|16|5)
- 1:   induced cell death variant [WBPhenotype:0001268] <2>(1|2) (1|1|0)
- 1:   cell degeneration [WBPhenotype:0000178] <1>(0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
DLC0Direct
RBP11-like subunits of RNA polymerase0Direct
PX domain0Direct
Subdomain of clathrin and coatomer appendage domain0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
VPS9 domain0Direct
Clathrin adaptor appendage domain0Direct
Calpain large subunit, middle domain (domain III)0.0000004494Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase0.0000007698Direct
Cullin repeat-like0.000001838Direct
FYVE/PHD zinc finger0.000004267Direct
Skp1 dimerisation domain-like0.00001478Direct
Integrin domains0.0001135Direct
Terpenoid cyclases/Protein prenyltransferases0.0001135Direct
Tubby C-terminal domain-like0.0005002Direct
Caspase-like0.0005002Direct
Cupredoxins0.0005002Direct
Cullin homology domain0.001028Inherited
Protein kinase-like (PK-like)0.001354Inherited
GroEL apical domain-like0.002044Inherited
GroEL equatorial domain-like0.00532Inherited
GroEL-intermediate domain like0.00532Inherited
ENTH/VHS domain0.006743Inherited
Sm-like ribonucleoproteins0.006743Inherited
SET domain0.007422Inherited
Cysteine proteinases0.0137Inherited
BAR/IMD domain-like0.01612Inherited
Calcium ATPase, transmembrane domain M0.01643Inherited
Metal cation-transporting ATPase, ATP-binding domain N0.01643Inherited
DNA repair protein MutS, domain III0.02433Inherited
5' to 3' exonuclease, C-terminal subdomain0.02433Inherited
F1F0 ATP synthase subunit C0.02433Inherited
DEATH domain0.03337Inherited
Activating enzymes of the ubiquitin-like proteins0.03337Inherited
Calcium ATPase, transduction domain A0.03518Inherited
SH3-domain0.04825Inherited
HLH, helix-loop-helix DNA-binding domain0.06977Inherited
Sec1/munc18-like (SM) proteins0.07968Inherited
Hect, E3 ligase catalytic domain0.07968Inherited
PH domain-like0.08045Inherited
ARM repeat0.141Inherited
Lamin A/C globular tail domain0.1419Inherited
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.1617Inherited
PIN domain-like0.1617Inherited
SNARE-like0.1877Inherited
POZ domain0.1941Inherited
Saposin0.2143Inherited
Intermediate filament protein, coiled coil region0.2614Inherited
Chromo domain-like0.3668Inherited
"Winged helix" DNA-binding domain0.4088Inherited
Metallo-dependent phosphatases0.43Inherited
Nucleic acid-binding proteins0.4778Inherited
Histone-fold0.5637Inherited
PLP-dependent transferases0.5729Inherited
WD40 repeat-like0.6253Inherited
S-adenosyl-L-methionine-dependent methyltransferases0.7036Inherited
RNA-binding domain, RBD0.9483Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Arginine methyltransferase0Direct
RNA-polymerase beta0Direct
Integrin domains0Direct
Phoshoinositide 3-kinase (PI3K) helical domain0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Group II chaperonin (CCT, TRIC), intermediate domain0Direct
Myotubularin-like phosphatases0Direct
Cullin repeat0Direct
Protein prenyltransferases0Direct
PX domain0Direct
SCF ubiquitin ligase complex WHB domain0Direct
DLC0Direct
FYVE, a phosphatidylinositol-3-phosphate binding domain0.000000000000001256Direct
Calpain large subunit, middle domain (domain III)0.000001288Direct
RecA protein-like (ATPase-domain)0.000001844Direct
Skp1 dimerisation domain-like0.00001572Direct
Caspase catalytic domain0.0001857Direct
Ephrin ectodomain0.0001857Direct
Calpain large subunit, catalytic domain (domain II)0.0002918Direct
Group II chaperonin (CCT, TRIC), apical domain0.0003223Direct
Cullin homology domain0.0009363Direct
Group II chaperonin (CCT, TRIC), ATPase domain0.0009363Direct
Phoshoinositide 3-kinase (PI3K), catalytic domain0.001911Inherited
BTB/POZ domain0.008039Inherited
Sm motif of small nuclear ribonucleoproteins, SNRNP0.01259Inherited
Histone lysine methyltransferases0.01494Inherited
G proteins0.0164Inherited
Protein kinases, catalytic subunit0.01647Inherited
Ubiquitin activating enzymes (UBA)0.02215Inherited
F1F0 ATP synthase subunit C0.02215Inherited
DNA repair protein MutS, domain III0.02215Inherited
BAR domain0.02215Inherited
5' to 3' exonuclease, C-terminal subdomain0.02215Inherited
5' to 3' exonuclease catalytic domain0.02215Inherited
Cold shock DNA-binding domain-like0.02992Inherited
Calcium ATPase, transduction domain A0.03381Inherited
SH3-domain0.05036Inherited
HLH, helix-loop-helix DNA-binding domain0.06981Inherited
Clathrin adaptor core protein0.07406Inherited
Sec1/munc18-like (SM) proteins0.07442Inherited
Hect, E3 ligase catalytic domain0.07442Inherited
Phosphotyrosine-binding domain (PTB)0.1197Inherited
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.1545Inherited
Intermediate filament protein, coiled coil region0.2536Inherited
Translational machinery components0.2536Inherited
Armadillo repeat0.3025Inherited
Nucleosome core histones0.5519Inherited
Proteasome subunits0.6548Inherited
ABC transporter ATPase domain-like0.861Inherited
Canonical RBD0.9455Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Clathrin adaptor appendage domain0Direct
RBP11-like subunits of RNA polymerase0Direct
VPS9 domain0Direct
PX domain0Direct
DLC0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Subdomain of clathrin and coatomer appendage domain0Direct
Calpain large subunit, middle domain (domain III)0.0000003607Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase0.0000006194Direct
Cullin repeat-like0.000001483Direct
FYVE/PHD zinc finger0.000003448Direct
Skp1 dimerisation domain-like0.00001198Direct
Terpenoid cyclases/Protein prenyltransferases0.00009267Direct
Integrin domains0.00009267Direct
Cupredoxins0.0004122Direct
Caspase-like0.0004122Direct
Tubby C-terminal domain-like0.0004122Direct
Cullin homology domain0.0008522Direct
Protein kinase-like (PK-like)0.001126Inherited
GroEL apical domain-like0.00171Inherited
GroEL-intermediate domain like0.004505Inherited
GroEL equatorial domain-like0.004505Inherited
ENTH/VHS domain0.00573Inherited
Sm-like ribonucleoproteins0.00573Inherited
SET domain0.006316Inherited
Cysteine proteinases0.01179Inherited
BAR/IMD domain-like0.01391Inherited
Calcium ATPase, transmembrane domain M0.01418Inherited
Metal cation-transporting ATPase, ATP-binding domain N0.01418Inherited
F1F0 ATP synthase subunit C0.0212Inherited
DNA repair protein MutS, domain III0.0212Inherited
FAD/NAD-linked reductases, dimerisation (C-terminal) domain0.0212Inherited
5' to 3' exonuclease, C-terminal subdomain0.0212Inherited
Activating enzymes of the ubiquitin-like proteins0.0292Inherited
DEATH domain0.0292Inherited
Calcium ATPase, transduction domain A0.03081Inherited
SH3-domain0.04255Inherited
HLH, helix-loop-helix DNA-binding domain0.06208Inherited
Sec1/munc18-like (SM) proteins0.07119Inherited
Hect, E3 ligase catalytic domain0.07119Inherited
PH domain-like0.07189Inherited
ARM repeat0.1283Inherited
Lamin A/C globular tail domain0.129Inherited
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.1477Inherited
PIN domain-like0.1477Inherited
SNARE-like0.172Inherited
POZ domain0.1782Inherited
Saposin0.1976Inherited
Intermediate filament protein, coiled coil region0.2428Inherited
Chromo domain-like0.3458Inherited
"Winged helix" DNA-binding domain0.3867Inherited
Metallo-dependent phosphatases0.4077Inherited
Nucleic acid-binding proteins0.4554Inherited
Histone-fold0.5412Inherited
PLP-dependent transferases0.5506Inherited
WD40 repeat-like0.6034Inherited
S-adenosyl-L-methionine-dependent methyltransferases0.6833Inherited
RNA-binding domain, RBD0.9366Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
52540,47917
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase
  • 0Direct
    49562,48371
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 0Direct
    74788,75632
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 0Direct
    49348,55711
  • 49348 - Clathrin adaptor appendage domain
  • 55711 - Subdomain of clathrin and coatomer appendage domain
  • 0Direct
    75632,46785
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    54001,49758
  • 54001 - Cysteine proteinases
  • 49758 - Calpain large subunit, middle domain (domain III)
  • 0.00000004949Direct
    48371,56112
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.000007648Direct
    54695,81382
  • 54695 - POZ domain
  • 81382 - Skp1 dimerisation domain-like
  • 0.00003083Direct
    81333,81333
  • 81333 - F1F0 ATP synthase subunit C
  • 81333 - F1F0 ATP synthase subunit C
  • 0.00009267Direct
    54849,52029
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.004505Inherited
    48592,54849
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 0.004505Inherited
    81660,56784
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 0.01418Inherited
    51905,55424
  • 51905 - FAD/NAD(P)-binding domain
  • 55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain
  • 0.0212Inherited
    48334,52540
  • 48334 - DNA repair protein MutS, domain III
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.0212Inherited
    57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.1477Inherited
    54928,54928
  • 54928 - RNA-binding domain, RBD
  • 54928 - RNA-binding domain, RBD
  • 0.172Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.3402Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    74788,75632,46785
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    49562,48371,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    48592,54849,52029
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.004505Inherited
    81660,56784,81665
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 81665 - Calcium ATPase, transmembrane domain M
  • 0.01418Inherited
    57424,57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.1477Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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