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Worm Phenotype (WP): apoptosis variant

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Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)

Shortest distance to current term (+ for parents, - for children) WP term [WP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + 5:   Variant [WBPhenotype:0000886] <2>
+ + + + 4:   physiology variant [WBPhenotype:0000519] <15>(509|582) (509|247|68)
+ + + 3:   cell physiology variant [WBPhenotype:0000536] <35>(156|154) (158|67|19)
+ + 2:   cell death variant [WBPhenotype:0000729] <3>(58|51) (58|15|5)
+ 1:   programmed cell death variant [WBPhenotype:0001172] <3>(56|48) (56|14|5)
0:   apoptosis variant [WBPhenotype:0000730] <13>(51|44) (51|12|5)
- 1:   engulfment variant [WBPhenotype:0000885] <4>(1|1) (1|0|0)
- 1:   apoptosis increased [WBPhenotype:0000183] <2>(7|8) (7|3|1)
- 1:   apoptosis reduced [WBPhenotype:0000182] <2>(3|4) (3|0|0)
- 1:   cell corpse number variant [WBPhenotype:0000590] <2>(29|29) (29|9|5)
- 1:   cell death sexually dimorphic variant [WBPhenotype:0001218] <2>(0|0) (0|0|0)
- 1:   mutagen induced apoptosis variant [WBPhenotype:0002152] <2>(4|1) (4|0|0)
- 1:   apoptosis protracted [WBPhenotype:0000185] <1>(2|2) (2|0|0)
- 1:   apoptotic DNA degradation defective [WBPhenotype:0002201](0|0) (0|0|0)
- 1:   apoptotic arrest [WBPhenotype:0000244](0|0) (0|0|0)
- 1:   apoptotic cell shedding variant [WBPhenotype:0002180](0|0) (0|0|0)
- 1:   cell corpse degradation variant [WBPhenotype:0010004](2|2) (2|0|0)
- 1:   corpse morphology variant [WBPhenotype:0002203](0|0) (0|0|0)
- 1:   starvation induced apoptosis variant [WBPhenotype:0002184](1|1) (1|1|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
RBP11-like subunits of RNA polymerase0Direct
VPS9 domain0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
DLC0Direct
Clathrin adaptor appendage domain0Direct
Subdomain of clathrin and coatomer appendage domain0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
PX domain0Direct
Skp1 dimerisation domain-like0.00000000000002745Direct
Cullin homology domain0.00000003585Direct
GroEL apical domain-like0.0000001002Direct
PH domain-like0.0000002582Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase0.0000004836Direct
Cullin repeat-like0.000001078Direct
GroEL equatorial domain-like0.000001078Direct
GroEL-intermediate domain like0.000001078Direct
ENTH/VHS domain0.000004789Direct
Histone-fold0.000009121Direct
Sm-like ribonucleoproteins0.00005057Direct
SH3-domain0.00005117Direct
Nucleic acid-binding proteins0.00005117Direct
"Winged helix" DNA-binding domain0.00005823Direct
Integrin domains0.0000834Direct
5' to 3' exonuclease, C-terminal subdomain0.0000834Direct
BAR/IMD domain-like0.0002156Direct
Activating enzymes of the ubiquitin-like proteins0.0002654Direct
Tubby C-terminal domain-like0.0003702Direct
Cupredoxins0.0003702Direct
DEATH domain0.0005442Direct
SNARE-like0.0007082Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.0009974Direct
Sec1/munc18-like (SM) proteins0.0009974Direct
Metal cation-transporting ATPase, ATP-binding domain N0.001281Inherited
Lamin A/C globular tail domain0.001665Inherited
Calcium ATPase, transmembrane domain M0.001733Inherited
HLH, helix-loop-helix DNA-binding domain0.003174Inherited
PIN domain-like0.003819Inherited
Calcium ATPase, transduction domain A0.005514Inherited
Hect, E3 ligase catalytic domain0.006219Inherited
Intermediate filament protein, coiled coil region0.01358Inherited
Chromo domain-like0.09623Inherited
POZ domain0.1027Inherited
ARM repeat0.1432Inherited
Saposin0.1745Inherited
RNA-binding domain, RBD0.2316Inherited
PLP-dependent transferases0.4976Inherited
S-adenosyl-L-methionine-dependent methyltransferases0.5645Inherited
SET domain0.7654Inherited
FYVE/PHD zinc finger0.835Inherited
Metallo-dependent phosphatases0.8778Inherited
Protein kinase-like (PK-like)0.9813Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
DLC0Direct
Myotubularin-like phosphatases0Direct
Integrin domains0Direct
SCF ubiquitin ligase complex WHB domain0Direct
Phoshoinositide 3-kinase (PI3K) helical domain0Direct
PX domain0Direct
RNA-polymerase beta0Direct
Arginine methyltransferase0Direct
Cullin repeat0Direct
Group II chaperonin (CCT, TRIC), intermediate domain0Direct
FYVE, a phosphatidylinositol-3-phosphate binding domain3.127e-16Direct
Skp1 dimerisation domain-like0.0000000000000982Direct
Group II chaperonin (CCT, TRIC), apical domain0.00000007018Direct
Cullin homology domain0.00000009722Direct
Group II chaperonin (CCT, TRIC), ATPase domain0.0000007031Direct
RecA protein-like (ATPase-domain)0.000001089Direct
Nucleosome core histones0.00003124Direct
BTB/POZ domain0.00006647Direct
Phoshoinositide 3-kinase (PI3K), catalytic domain0.00006678Direct
G proteins0.00007032Direct
5' to 3' exonuclease catalytic domain0.0001309Direct
Ephrin ectodomain0.0001309Direct
5' to 3' exonuclease, C-terminal subdomain0.0001309Direct
Cold shock DNA-binding domain-like0.0001677Direct
Clathrin adaptor core protein0.0002022Direct
SH3-domain0.0003205Direct
BAR domain0.0005785Direct
Ubiquitin activating enzymes (UBA)0.0005785Direct
Phosphotyrosine-binding domain (PTB)0.00092Direct
Sm motif of small nuclear ribonucleoproteins, SNRNP0.00092Direct
Sec1/munc18-like (SM) proteins0.00155Inherited
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.00155Inherited
Armadillo repeat0.004626Inherited
Translational machinery components0.005882Inherited
HLH, helix-loop-helix DNA-binding domain0.008558Inherited
Hect, E3 ligase catalytic domain0.00958Inherited
Proteasome subunits0.009657Inherited
Calcium ATPase, transduction domain A0.0108Inherited
Intermediate filament protein, coiled coil region0.02082Inherited
Canonical RBD0.3109Inherited
Histone lysine methyltransferases0.8099Inherited
Protein kinases, catalytic subunit0.9968Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Subdomain of clathrin and coatomer appendage domain0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Clathrin adaptor appendage domain0Direct
DLC0Direct
RBP11-like subunits of RNA polymerase0Direct
VPS9 domain0Direct
PX domain0Direct
Skp1 dimerisation domain-like0.00000000000002162Direct
Cullin homology domain0.00000002878Direct
GroEL apical domain-like0.00000008055Direct
PH domain-like0.0000002083Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase0.0000003908Direct
Cullin repeat-like0.0000008742Direct
GroEL equatorial domain-like0.0000008742Direct
GroEL-intermediate domain like0.0000008742Direct
ENTH/VHS domain0.000003903Direct
Histone-fold0.000007438Direct
Sm-like ribonucleoproteins0.00004146Direct
SH3-domain0.00004195Direct
Nucleic acid-binding proteins0.00004195Direct
"Winged helix" DNA-binding domain0.00004774Direct
5' to 3' exonuclease, C-terminal subdomain0.00006848Direct
Integrin domains0.00006848Direct
BAR/IMD domain-like0.0001778Direct
Activating enzymes of the ubiquitin-like proteins0.0002193Direct
Tubby C-terminal domain-like0.0003064Direct
Cupredoxins0.0003064Direct
DEATH domain0.0004516Direct
SNARE-like0.0005892Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.0008321Direct
Sec1/munc18-like (SM) proteins0.0008321Direct
Metal cation-transporting ATPase, ATP-binding domain N0.001072Inherited
Lamin A/C globular tail domain0.001395Inherited
Calcium ATPase, transmembrane domain M0.001453Inherited
HLH, helix-loop-helix DNA-binding domain0.002685Inherited
PIN domain-like0.003237Inherited
Calcium ATPase, transduction domain A0.004696Inherited
Hect, E3 ligase catalytic domain0.005307Inherited
Intermediate filament protein, coiled coil region0.01175Inherited
Chromo domain-like0.0869Inherited
POZ domain0.09288Inherited
ARM repeat0.1306Inherited
Saposin0.1602Inherited
RNA-binding domain, RBD0.2146Inherited
PLP-dependent transferases0.4762Inherited
S-adenosyl-L-methionine-dependent methyltransferases0.543Inherited
SET domain0.7462Inherited
FYVE/PHD zinc finger0.8174Inherited
Metallo-dependent phosphatases0.862Inherited
Protein kinase-like (PK-like)0.9706Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
74788,75632
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 0Direct
    52540,47917
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase
  • 0Direct
    75632,46785
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    49562,48371
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 0Direct
    49348,55711
  • 49348 - Clathrin adaptor appendage domain
  • 55711 - Subdomain of clathrin and coatomer appendage domain
  • 0Direct
    54695,81382
  • 54695 - POZ domain
  • 81382 - Skp1 dimerisation domain-like
  • 0.00000000000006128Direct
    48592,54849
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 0.0000008742Direct
    54849,52029
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.0000008742Direct
    48371,56112
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.0003064Direct
    81660,56784
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 0.001072Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.007759Inherited
    54928,54928
  • 54928 - RNA-binding domain, RBD
  • 54928 - RNA-binding domain, RBD
  • 0.009716Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    74788,75632,46785
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    49562,48371,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    48592,54849,52029
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.0000008742Direct
    81660,56784,81665
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 81665 - Calcium ATPase, transmembrane domain M
  • 0.0007723Direct
    57424,57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.01175Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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