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Worm Phenotype (WP): apoptosis variant

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Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)

Shortest distance to current term (+ for parents, - for children) WP term [WP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + 5:   Variant [WBPhenotype:0000886] <5>
+ + + + 4:   physiology variant [WBPhenotype:0000519] <6>(494|573) (495|248|68)
+ + + 3:   cell physiology variant [WBPhenotype:0000536] <27>(145|146) (146|64|17)
+ + 2:   cell death variant [WBPhenotype:0000729] <3>(58|51) (59|17|5)
+ 1:   programmed cell death variant [WBPhenotype:0001172] <3>(56|48) (57|16|5)
0:   apoptosis variant [WBPhenotype:0000730] <13>(51|44) (51|13|5)
- 1:   engulfment variant [WBPhenotype:0000885] <4>(1|1) (1|0|0)
- 1:   apoptosis increased [WBPhenotype:0000183] <2>(7|8) (7|3|1)
- 1:   apoptosis reduced [WBPhenotype:0000182] <2>(3|4) (3|0|0)
- 1:   cell corpse number variant [WBPhenotype:0000590] <2>(29|29) (30|10|5)
- 1:   cell death sexually dimorphic variant [WBPhenotype:0001218] <2>(0|0) (0|0|0)
- 1:   mutagen induced apoptosis variant [WBPhenotype:0002152] <2>(4|1) (4|0|0)
- 1:   apoptosis protracted [WBPhenotype:0000185] <1>(2|2) (2|0|0)
- 1:   apoptotic DNA degradation defective [WBPhenotype:0002201](0|0) (0|0|0)
- 1:   apoptotic arrest [WBPhenotype:0000244](0|0) (0|0|0)
- 1:   apoptotic cell shedding variant [WBPhenotype:0002180](0|0) (0|0|0)
- 1:   cell corpse degradation variant [WBPhenotype:0010004](2|2) (2|0|0)
- 1:   corpse morphology variant [WBPhenotype:0002203](0|0) (0|0|0)
- 1:   starvation induced apoptosis variant [WBPhenotype:0002184](1|1) (1|1|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
VPS9 domain0Direct
RBP11-like subunits of RNA polymerase0Direct
DLC0Direct
Subdomain of clathrin and coatomer appendage domain0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Clathrin adaptor appendage domain0Direct
PX domain0Direct
Skp1 dimerisation domain-like0.0000000000000178Direct
Cullin homology domain0.00000002962Direct
GroEL apical domain-like0.00000008078Direct
PH domain-like0.0000001475Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase0.000000411Direct
GroEL equatorial domain-like0.0000008957Direct
GroEL-intermediate domain like0.0000008957Direct
Cullin repeat-like0.0000008957Direct
ENTH/VHS domain0.000003912Direct
Histone-fold0.000006039Direct
SH3-domain0.00003723Direct
Nucleic acid-binding proteins0.00003723Direct
"Winged helix" DNA-binding domain0.00003942Direct
Sm-like ribonucleoproteins0.00004165Direct
5' to 3' exonuclease, C-terminal subdomain0.00007523Direct
Integrin domains0.00007523Direct
BAR/IMD domain-like0.0001754Direct
Activating enzymes of the ubiquitin-like proteins0.0002346Direct
Cupredoxins0.0003346Direct
Tubby C-terminal domain-like0.0003346Direct
DEATH domain0.0004822Direct
SNARE-like0.0006139Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.0009038Direct
Sec1/munc18-like (SM) proteins0.0009038Direct
Metal cation-transporting ATPase, ATP-binding domain N0.001094Inherited
Lamin A/C globular tail domain0.001479Inherited
Calcium ATPase, transmembrane domain M0.001484Inherited
HLH, helix-loop-helix DNA-binding domain0.002639Inherited
PIN domain-like0.003466Inherited
Calcium ATPase, transduction domain A0.004864Inherited
Hect, E3 ligase catalytic domain0.005697Inherited
Intermediate filament protein, coiled coil region0.01249Inherited
Chromo domain-like0.0908Inherited
POZ domain0.09354Inherited
Saposin0.1659Inherited
ARM repeat0.174Inherited
RNA-binding domain, RBD0.2082Inherited
PLP-dependent transferases0.4867Inherited
S-adenosyl-L-methionine-dependent methyltransferases0.5786Inherited
SET domain0.7891Inherited
FYVE/PHD zinc finger0.8611Inherited
Metallo-dependent phosphatases0.8987Inherited
Protein kinase-like (PK-like)1Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Phoshoinositide 3-kinase (PI3K) helical domain0Direct
Integrin domains0Direct
PX domain0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Myotubularin-like phosphatases0Direct
DLC0Direct
Cullin repeat0Direct
RNA-polymerase beta0Direct
Group II chaperonin (CCT, TRIC), intermediate domain0Direct
SCF ubiquitin ligase complex WHB domain0Direct
Arginine methyltransferase0Direct
FYVE, a phosphatidylinositol-3-phosphate binding domain3.149e-16Direct
Skp1 dimerisation domain-like0.00000000000007165Direct
Group II chaperonin (CCT, TRIC), apical domain0.00000006015Direct
Cullin homology domain0.00000008483Direct
Group II chaperonin (CCT, TRIC), ATPase domain0.0000006155Direct
RecA protein-like (ATPase-domain)0.0000009725Direct
Nucleosome core histones0.00002373Direct
BTB/POZ domain0.00004182Direct
G proteins0.00004997Direct
Phoshoinositide 3-kinase (PI3K), catalytic domain0.00006Direct
5' to 3' exonuclease, C-terminal subdomain0.0001221Direct
5' to 3' exonuclease catalytic domain0.0001221Direct
Ephrin ectodomain0.0001221Direct
Cold shock DNA-binding domain-like0.000145Direct
Clathrin adaptor core protein0.0001856Direct
SH3-domain0.0002597Direct
BAR domain0.0005399Direct
Ubiquitin activating enzymes (UBA)0.0005399Direct
Sm motif of small nuclear ribonucleoproteins, SNRNP0.0008328Direct
Phosphotyrosine-binding domain (PTB)0.0008328Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.001451Inherited
Sec1/munc18-like (SM) proteins0.001451Inherited
Armadillo repeat0.004294Inherited
Translational machinery components0.005547Inherited
HLH, helix-loop-helix DNA-binding domain0.007628Inherited
Proteasome subunits0.009016Inherited
Hect, E3 ligase catalytic domain0.009059Inherited
Calcium ATPase, transduction domain A0.009962Inherited
Intermediate filament protein, coiled coil region0.01973Inherited
Canonical RBD0.2931Inherited
Histone lysine methyltransferases0.8317Inherited
Protein kinases, catalytic subunit1Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Subdomain of clathrin and coatomer appendage domain0Direct
Clathrin adaptor appendage domain0Direct
PX domain0Direct
VPS9 domain0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
DLC0Direct
RBP11-like subunits of RNA polymerase0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Skp1 dimerisation domain-like0.00000000000001387Direct
Cullin homology domain0.00000002352Direct
GroEL apical domain-like0.00000006433Direct
PH domain-like0.0000001176Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase0.000000329Direct
GroEL-intermediate domain like0.0000007192Direct
Cullin repeat-like0.0000007192Direct
GroEL equatorial domain-like0.0000007192Direct
ENTH/VHS domain0.000003154Direct
Histone-fold0.000004877Direct
Nucleic acid-binding proteins0.00003023Direct
SH3-domain0.00003023Direct
"Winged helix" DNA-binding domain0.00003199Direct
Sm-like ribonucleoproteins0.00003382Direct
Integrin domains0.00006121Direct
5' to 3' exonuclease, C-terminal subdomain0.00006121Direct
BAR/IMD domain-like0.0001432Direct
Activating enzymes of the ubiquitin-like proteins0.0001918Direct
Tubby C-terminal domain-like0.0002743Direct
Cupredoxins0.0002743Direct
DEATH domain0.0003963Direct
SNARE-like0.000506Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.0007476Direct
Sec1/munc18-like (SM) proteins0.0007476Direct
Metal cation-transporting ATPase, ATP-binding domain N0.0009071Direct
Lamin A/C globular tail domain0.00123Inherited
Calcium ATPase, transmembrane domain M0.001234Inherited
HLH, helix-loop-helix DNA-binding domain0.002215Inherited
PIN domain-like0.002916Inherited
Calcium ATPase, transduction domain A0.004112Inherited
Hect, E3 ligase catalytic domain0.004827Inherited
Intermediate filament protein, coiled coil region0.01072Inherited
Chromo domain-like0.0815Inherited
POZ domain0.08404Inherited
Saposin0.1516Inherited
ARM repeat0.1592Inherited
RNA-binding domain, RBD0.1917Inherited
PLP-dependent transferases0.4646Inherited
S-adenosyl-L-methionine-dependent methyltransferases0.5563Inherited
SET domain0.7712Inherited
FYVE/PHD zinc finger0.8463Inherited
Metallo-dependent phosphatases0.8852Inherited
Protein kinase-like (PK-like)1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
52540,47917
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase
  • 0Direct
    75632,46785
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    49348,55711
  • 49348 - Clathrin adaptor appendage domain
  • 55711 - Subdomain of clathrin and coatomer appendage domain
  • 0Direct
    74788,75632
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 0Direct
    49562,48371
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 0Direct
    54695,81382
  • 54695 - POZ domain
  • 81382 - Skp1 dimerisation domain-like
  • 0.00000000000004016Direct
    48592,54849
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 0.0000007192Direct
    54849,52029
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.0000007192Direct
    48371,56112
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.0002743Direct
    81660,56784
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 0.0009071Direct
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.00671Inherited
    54928,54928
  • 54928 - RNA-binding domain, RBD
  • 54928 - RNA-binding domain, RBD
  • 0.008534Inherited
    57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.02585Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    49562,48371,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    74788,75632,46785
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    48592,54849,52029
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.0000007192Direct
    81660,56784,81665
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 81665 - Calcium ATPase, transmembrane domain M
  • 0.0006523Direct
    57424,57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.01072Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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