SUPERFAMILY 1.75 HMM library and genome assignments server

Superfamily is undergoing a server migration - you are now browsing on the new server. Please contact us if you experience any problems.

Worm Phenotype (WP): apoptosis variant

(show info)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)

Shortest distance to current term (+ for parents, - for children) WP term [WP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + 5:   Variant [WBPhenotype:0000886] <2>
+ + + + 4:   physiology variant [WBPhenotype:0000519] <14>(510|587) (510|248|68)
+ + + 3:   cell physiology variant [WBPhenotype:0000536] <36>(149|149) (150|64|19)
+ + 2:   cell death variant [WBPhenotype:0000729] <3>(58|51) (58|15|5)
+ 1:   programmed cell death variant [WBPhenotype:0001172] <3>(56|48) (56|14|5)
0:   apoptosis variant [WBPhenotype:0000730] <13>(51|44) (51|12|5)
- 1:   engulfment variant [WBPhenotype:0000885] <4>(1|1) (1|0|0)
- 1:   apoptosis increased [WBPhenotype:0000183] <2>(7|8) (7|3|1)
- 1:   apoptosis reduced [WBPhenotype:0000182] <2>(3|4) (3|0|0)
- 1:   cell corpse number variant [WBPhenotype:0000590] <2>(29|29) (29|9|5)
- 1:   cell death sexually dimorphic variant [WBPhenotype:0001218] <2>(0|0) (0|0|0)
- 1:   mutagen induced apoptosis variant [WBPhenotype:0002152] <2>(4|1) (4|0|0)
- 1:   apoptosis protracted [WBPhenotype:0000185] <1>(2|2) (2|0|0)
- 1:   apoptotic DNA degradation defective [WBPhenotype:0002201](0|0) (0|0|0)
- 1:   apoptotic arrest [WBPhenotype:0000244](0|0) (0|0|0)
- 1:   apoptotic cell shedding variant [WBPhenotype:0002180](0|0) (0|0|0)
- 1:   cell corpse degradation variant [WBPhenotype:0010004](2|2) (2|0|0)
- 1:   corpse morphology variant [WBPhenotype:0002203](0|0) (0|0|0)
- 1:   starvation induced apoptosis variant [WBPhenotype:0002184](1|1) (1|1|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
PX domain0Direct
RBP11-like subunits of RNA polymerase0Direct
DLC0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
VPS9 domain0Direct
Subdomain of clathrin and coatomer appendage domain0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Clathrin adaptor appendage domain0Direct
Skp1 dimerisation domain-like0.0000000000000277Direct
Cullin homology domain0.00000003628Direct
GroEL apical domain-like0.0000001015Direct
PH domain-like0.0000002632Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase0.0000004887Direct
GroEL-intermediate domain like0.00000109Direct
GroEL equatorial domain-like0.00000109Direct
Cullin repeat-like0.00000109Direct
ENTH/VHS domain0.000004847Direct
Histone-fold0.000009257Direct
Sm-like ribonucleoproteins0.00005108Direct
Nucleic acid-binding proteins0.00005179Direct
SH3-domain0.00005179Direct
"Winged helix" DNA-binding domain0.00005899Direct
5' to 3' exonuclease, C-terminal subdomain0.00008403Direct
Integrin domains0.00008403Direct
BAR/IMD domain-like0.0002176Direct
Activating enzymes of the ubiquitin-like proteins0.0002675Direct
Tubby C-terminal domain-like0.0003732Direct
Cupredoxins0.0003732Direct
DEATH domain0.0005473Direct
SNARE-like0.0007132Direct
Sec1/munc18-like (SM) proteins0.001004Inherited
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.001004Inherited
Metal cation-transporting ATPase, ATP-binding domain N0.001291Inherited
Lamin A/C globular tail domain0.001675Inherited
Calcium ATPase, transmembrane domain M0.001744Inherited
HLH, helix-loop-helix DNA-binding domain0.003192Inherited
PIN domain-like0.003829Inherited
Calcium ATPase, transduction domain A0.005544Inherited
Hect, E3 ligase catalytic domain0.006245Inherited
Intermediate filament protein, coiled coil region0.01361Inherited
Chromo domain-like0.09645Inherited
POZ domain0.1031Inherited
ARM repeat0.1362Inherited
Saposin0.1746Inherited
RNA-binding domain, RBD0.326Inherited
PLP-dependent transferases0.4984Inherited
S-adenosyl-L-methionine-dependent methyltransferases0.5659Inherited
SET domain0.7664Inherited
FYVE/PHD zinc finger0.8364Inherited
Metallo-dependent phosphatases0.8797Inherited
Protein kinase-like (PK-like)0.9837Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
PX domain0Direct
Cullin repeat0Direct
DLC0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Myotubularin-like phosphatases0Direct
SCF ubiquitin ligase complex WHB domain0Direct
Group II chaperonin (CCT, TRIC), intermediate domain0Direct
RNA-polymerase beta0Direct
Phoshoinositide 3-kinase (PI3K) helical domain0Direct
Integrin domains0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Arginine methyltransferase0Direct
FYVE, a phosphatidylinositol-3-phosphate binding domain3.134e-16Direct
Skp1 dimerisation domain-like0.00000000000009845Direct
Group II chaperonin (CCT, TRIC), apical domain0.00000007055Direct
Cullin homology domain0.00000009769Direct
Group II chaperonin (CCT, TRIC), ATPase domain0.0000007061Direct
RecA protein-like (ATPase-domain)0.000001094Direct
Phoshoinositide 3-kinase (PI3K), catalytic domain0.000002869Direct
G proteins0.00002576Direct
Nucleosome core histones0.00003147Direct
BTB/POZ domain0.00006687Direct
Ephrin ectodomain0.0001313Direct
5' to 3' exonuclease catalytic domain0.0001313Direct
5' to 3' exonuclease, C-terminal subdomain0.0001313Direct
Cold shock DNA-binding domain-like0.0001683Direct
Clathrin adaptor core protein0.000203Direct
SH3-domain0.0003216Direct
BAR domain0.0005799Direct
Ubiquitin activating enzymes (UBA)0.0005799Direct
Phosphotyrosine-binding domain (PTB)0.0009215Direct
Sm motif of small nuclear ribonucleoproteins, SNRNP0.0009215Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.001553Inherited
Sec1/munc18-like (SM) proteins0.001553Inherited
Armadillo repeat0.004632Inherited
Translational machinery components0.005889Inherited
HLH, helix-loop-helix DNA-binding domain0.008571Inherited
Hect, E3 ligase catalytic domain0.009599Inherited
Proteasome subunits0.00968Inherited
Calcium ATPase, transduction domain A0.01083Inherited
Intermediate filament protein, coiled coil region0.0208Inherited
Canonical RBD0.4177Inherited
Histone lysine methyltransferases0.8102Inherited
Protein kinases, catalytic subunit1Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
Plot tree as:   Download Newick format tree:
(show help)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Clathrin adaptor appendage domain0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
RBP11-like subunits of RNA polymerase0Direct
VPS9 domain0Direct
Subdomain of clathrin and coatomer appendage domain0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
DLC0Direct
PX domain0Direct
Skp1 dimerisation domain-like0.00000000000002173Direct
Cullin homology domain0.00000002901Direct
GroEL apical domain-like0.00000008128Direct
PH domain-like0.0000002116Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase0.0000003937Direct
GroEL equatorial domain-like0.0000008809Direct
GroEL-intermediate domain like0.0000008809Direct
Cullin repeat-like0.0000008809Direct
ENTH/VHS domain0.000003939Direct
Histone-fold0.000007531Direct
Sm-like ribonucleoproteins0.00004179Direct
SH3-domain0.00004238Direct
Nucleic acid-binding proteins0.00004238Direct
"Winged helix" DNA-binding domain0.00004826Direct
Integrin domains0.00006881Direct
5' to 3' exonuclease, C-terminal subdomain0.00006881Direct
BAR/IMD domain-like0.0001789Direct
Activating enzymes of the ubiquitin-like proteins0.0002202Direct
Tubby C-terminal domain-like0.0003078Direct
Cupredoxins0.0003078Direct
DEATH domain0.0004532Direct
SNARE-like0.0005919Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.0008357Direct
Sec1/munc18-like (SM) proteins0.0008357Direct
Metal cation-transporting ATPase, ATP-binding domain N0.001077Inherited
Lamin A/C globular tail domain0.001401Inherited
Calcium ATPase, transmembrane domain M0.001459Inherited
HLH, helix-loop-helix DNA-binding domain0.002696Inherited
PIN domain-like0.003243Inherited
Calcium ATPase, transduction domain A0.004715Inherited
Hect, E3 ligase catalytic domain0.005322Inherited
Intermediate filament protein, coiled coil region0.01177Inherited
Chromo domain-like0.08701Inherited
POZ domain0.09316Inherited
ARM repeat0.124Inherited
Saposin0.1602Inherited
RNA-binding domain, RBD0.3065Inherited
PLP-dependent transferases0.4767Inherited
S-adenosyl-L-methionine-dependent methyltransferases0.5441Inherited
SET domain0.7473Inherited
FYVE/PHD zinc finger0.8189Inherited
Metallo-dependent phosphatases0.8638Inherited
Protein kinase-like (PK-like)0.9724Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
52540,47917
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase
  • 0Direct
    49562,48371
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 0Direct
    74788,75632
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 0Direct
    75632,46785
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    49348,55711
  • 49348 - Clathrin adaptor appendage domain
  • 55711 - Subdomain of clathrin and coatomer appendage domain
  • 0Direct
    54695,81382
  • 54695 - POZ domain
  • 81382 - Skp1 dimerisation domain-like
  • 0.0000000000000623Direct
    48592,54849
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 0.0000008809Direct
    54849,52029
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.0000008809Direct
    48371,56112
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.0003078Direct
    81660,56784
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 0.001077Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.007789Inherited
    54928,54928
  • 54928 - RNA-binding domain, RBD
  • 54928 - RNA-binding domain, RBD
  • 0.02783Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    49562,48371,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    74788,75632,46785
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    48592,54849,52029
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.0000008809Direct
    81660,56784,81665
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 81665 - Calcium ATPase, transmembrane domain M
  • 0.0007767Direct
    57424,57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.01177Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)