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Worm Phenotype (WP): apoptosis variant

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Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)

Shortest distance to current term (+ for parents, - for children) WP term [WP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + 5:   Variant [WBPhenotype:0000886] <5>
+ + + + 4:   physiology variant [WBPhenotype:0000519] <6>(495|573) (496|248|69)
+ + + 3:   cell physiology variant [WBPhenotype:0000536] <27>(145|146) (146|64|18)
+ + 2:   cell death variant [WBPhenotype:0000729] <3>(58|51) (59|17|5)
+ 1:   programmed cell death variant [WBPhenotype:0001172] <3>(56|48) (57|16|5)
0:   apoptosis variant [WBPhenotype:0000730] <13>(51|44) (51|13|5)
- 1:   engulfment variant [WBPhenotype:0000885] <4>(1|1) (1|0|0)
- 1:   apoptosis increased [WBPhenotype:0000183] <2>(7|8) (7|3|1)
- 1:   apoptosis reduced [WBPhenotype:0000182] <2>(3|4) (3|0|0)
- 1:   cell corpse number variant [WBPhenotype:0000590] <2>(29|29) (30|10|5)
- 1:   cell death sexually dimorphic variant [WBPhenotype:0001218] <2>(0|0) (0|0|0)
- 1:   mutagen induced apoptosis variant [WBPhenotype:0002152] <2>(4|1) (4|0|0)
- 1:   apoptosis protracted [WBPhenotype:0000185] <1>(2|2) (2|0|0)
- 1:   apoptotic DNA degradation defective [WBPhenotype:0002201](0|0) (0|0|0)
- 1:   apoptotic arrest [WBPhenotype:0000244](0|0) (0|0|0)
- 1:   apoptotic cell shedding variant [WBPhenotype:0002180](0|0) (0|0|0)
- 1:   cell corpse degradation variant [WBPhenotype:0010004](2|2) (2|0|0)
- 1:   corpse morphology variant [WBPhenotype:0002203](0|0) (0|0|0)
- 1:   starvation induced apoptosis variant [WBPhenotype:0002184](1|1) (1|1|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
VPS9 domain0Direct
Clathrin adaptor appendage domain0Direct
Subdomain of clathrin and coatomer appendage domain0Direct
PX domain0Direct
DLC0Direct
RBP11-like subunits of RNA polymerase0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Skp1 dimerisation domain-like0.00000000000001905Direct
Cullin homology domain0.00000003058Direct
GroEL apical domain-like0.00000008375Direct
PH domain-like0.0000001632Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase0.0000004223Direct
Cullin repeat-like0.0000009244Direct
GroEL-intermediate domain like0.0000009244Direct
GroEL equatorial domain-like0.0000009244Direct
ENTH/VHS domain0.000004052Direct
Histone-fold0.00000651Direct
Nucleic acid-binding proteins0.00003949Direct
SH3-domain0.00003949Direct
"Winged helix" DNA-binding domain0.00004234Direct
Sm-like ribonucleoproteins0.00004313Direct
Integrin domains0.00007665Direct
5' to 3' exonuclease, C-terminal subdomain0.00007665Direct
BAR/IMD domain-like0.0001823Direct
Activating enzymes of the ubiquitin-like proteins0.0002403Direct
Tubby C-terminal domain-like0.0003409Direct
Cupredoxins0.0003409Direct
DEATH domain0.0004929Direct
SNARE-like0.0006299Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.0009209Direct
Sec1/munc18-like (SM) proteins0.0009209Direct
Metal cation-transporting ATPase, ATP-binding domain N0.001128Inherited
Lamin A/C globular tail domain0.001515Inherited
Calcium ATPase, transmembrane domain M0.00153Inherited
HLH, helix-loop-helix DNA-binding domain0.002734Inherited
PIN domain-like0.003527Inherited
Calcium ATPase, transduction domain A0.004984Inherited
Hect, E3 ligase catalytic domain0.0058Inherited
Intermediate filament protein, coiled coil region0.0127Inherited
Chromo domain-like0.09216Inherited
POZ domain0.1013Inherited
Saposin0.1681Inherited
ARM repeat0.176Inherited
RNA-binding domain, RBD0.2135Inherited
PLP-dependent transferases0.4914Inherited
S-adenosyl-L-methionine-dependent methyltransferases0.5849Inherited
SET domain0.7915Inherited
Metallo-dependent phosphatases0.8615Inherited
FYVE/PHD zinc finger0.8645Inherited
Protein kinase-like (PK-like)1Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Group II chaperonin (CCT, TRIC), intermediate domain0Direct
Cullin repeat0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Myotubularin-like phosphatases0Direct
SCF ubiquitin ligase complex WHB domain0Direct
RNA-polymerase beta0Direct
PX domain0Direct
Phoshoinositide 3-kinase (PI3K) helical domain0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
DLC0Direct
Integrin domains0Direct
Arginine methyltransferase0Direct
FYVE, a phosphatidylinositol-3-phosphate binding domain3.144e-16Direct
Skp1 dimerisation domain-like0.00000000000007745Direct
Group II chaperonin (CCT, TRIC), apical domain0.00000006255Direct
Cullin homology domain0.00000008777Direct
Group II chaperonin (CCT, TRIC), ATPase domain0.0000006367Direct
RecA protein-like (ATPase-domain)0.000001001Direct
G proteins0.00001949Direct
Nucleosome core histones0.00002544Direct
BTB/POZ domain0.00004455Direct
Phoshoinositide 3-kinase (PI3K), catalytic domain0.00006173Direct
Ephrin ectodomain0.0001245Direct
5' to 3' exonuclease, C-terminal subdomain0.0001245Direct
5' to 3' exonuclease catalytic domain0.0001245Direct
Cold shock DNA-binding domain-like0.0001507Direct
Clathrin adaptor core protein0.00019Direct
SH3-domain0.0002744Direct
BAR domain0.0005511Direct
Ubiquitin activating enzymes (UBA)0.0005511Direct
Phosphotyrosine-binding domain (PTB)0.0008569Direct
Sm motif of small nuclear ribonucleoproteins, SNRNP0.0008569Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.00148Inherited
Sec1/munc18-like (SM) proteins0.00148Inherited
Armadillo repeat0.004396Inherited
Translational machinery components0.005659Inherited
HLH, helix-loop-helix DNA-binding domain0.007889Inherited
Proteasome subunits0.009218Inherited
Hect, E3 ligase catalytic domain0.009233Inherited
Calcium ATPase, transduction domain A0.01022Inherited
Intermediate filament protein, coiled coil region0.02013Inherited
Canonical RBD0.2991Inherited
Histone lysine methyltransferases0.8327Inherited
Protein kinases, catalytic subunit1Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Clathrin adaptor appendage domain0Direct
DLC0Direct
Subdomain of clathrin and coatomer appendage domain0Direct
VPS9 domain0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
PX domain0Direct
RBP11-like subunits of RNA polymerase0Direct
Skp1 dimerisation domain-like0.00000000000001488Direct
Cullin homology domain0.00000002436Direct
GroEL apical domain-like0.00000006688Direct
PH domain-like0.0000001305Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase0.0000003388Direct
Cullin repeat-like0.0000007438Direct
GroEL equatorial domain-like0.0000007438Direct
GroEL-intermediate domain like0.0000007438Direct
ENTH/VHS domain0.000003275Direct
Histone-fold0.000005269Direct
Nucleic acid-binding proteins0.0000321Direct
SH3-domain0.0000321Direct
"Winged helix" DNA-binding domain0.00003443Direct
Sm-like ribonucleoproteins0.00003508Direct
Integrin domains0.00006245Direct
5' to 3' exonuclease, C-terminal subdomain0.00006245Direct
BAR/IMD domain-like0.000149Direct
Activating enzymes of the ubiquitin-like proteins0.0001966Direct
Cupredoxins0.0002798Direct
Tubby C-terminal domain-like0.0002798Direct
DEATH domain0.0004058Direct
SNARE-like0.0005199Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.0007624Direct
Sec1/munc18-like (SM) proteins0.0007624Direct
Metal cation-transporting ATPase, ATP-binding domain N0.0009356Direct
Lamin A/C globular tail domain0.00126Inherited
Calcium ATPase, transmembrane domain M0.001273Inherited
HLH, helix-loop-helix DNA-binding domain0.002296Inherited
PIN domain-like0.002969Inherited
Calcium ATPase, transduction domain A0.004217Inherited
Hect, E3 ligase catalytic domain0.004917Inherited
Intermediate filament protein, coiled coil region0.01091Inherited
Chromo domain-like0.08269Inherited
POZ domain0.09119Inherited
Saposin0.1537Inherited
ARM repeat0.161Inherited
RNA-binding domain, RBD0.1968Inherited
PLP-dependent transferases0.4689Inherited
S-adenosyl-L-methionine-dependent methyltransferases0.5626Inherited
SET domain0.7736Inherited
Metallo-dependent phosphatases0.8465Inherited
FYVE/PHD zinc finger0.8496Inherited
Protein kinase-like (PK-like)1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
49562,48371
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 0Direct
    52540,47917
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase
  • 0Direct
    49348,55711
  • 49348 - Clathrin adaptor appendage domain
  • 55711 - Subdomain of clathrin and coatomer appendage domain
  • 0Direct
    75632,46785
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    74788,75632
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 0Direct
    54695,81382
  • 54695 - POZ domain
  • 81382 - Skp1 dimerisation domain-like
  • 0.00000000000004352Direct
    54849,52029
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.0000007438Direct
    48592,54849
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 0.0000007438Direct
    48371,56112
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.0002798Direct
    81660,56784
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 0.0009356Direct
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.006895Inherited
    54928,54928
  • 54928 - RNA-binding domain, RBD
  • 54928 - RNA-binding domain, RBD
  • 0.008748Inherited
    57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.0263Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    49562,48371,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    74788,75632,46785
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    48592,54849,52029
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.0000007438Direct
    81660,56784,81665
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 81665 - Calcium ATPase, transmembrane domain M
  • 0.0006726Direct
    57424,57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.01091Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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