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Worm Phenotype (WP): cell cycle variant

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Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)

Shortest distance to current term (+ for parents, - for children) WP term [WP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   Variant [WBPhenotype:0000886] <2>
+ + 2:   physiology variant [WBPhenotype:0000519] <14>(510|587) (510|248|68)
+ 1:   cell physiology variant [WBPhenotype:0000536] <36>(149|149) (150|64|19)
0:   cell cycle variant [WBPhenotype:0000740] <6>(35|35) (35|17|4)
- 1:   meiosis variant [WBPhenotype:0000775] <10>(34|32) (34|14|4)
- 1:   cell cycle progression variant [WBPhenotype:0001995] <4>(1|1) (1|1|0)
- 1:   DNA damage checkpoint variant [WBPhenotype:0000741] <3>(0|0) (0|0|0)
- 1:   metaphase to anaphase transition defect [WBPhenotype:0001496] <2>(1|1) (1|1|0)
- 1:   cell cycle defective early emb [WBPhenotype:0001114] <1>(2|2) (2|0|0)
- 1:   interphase entry defective early emb [WBPhenotype:0001043](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Smc hinge domain0Direct
LEM domain0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
The spindle assembly checkpoint protein mad20Direct
Skp1 dimerisation domain-like0.0000000678Direct
P-loop containing nucleoside triphosphate hydrolases0.00000008389Direct
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.0000002227Direct
Nucleic acid-binding proteins0.000006681Direct
ADC-like0.00006709Direct
Cdc48 domain 2-like0.00006709Direct
GroEL-intermediate domain like0.00008506Direct
GroEL equatorial domain-like0.00008506Direct
Sm-like ribonucleoproteins0.0001688Direct
POZ domain0.0001887Direct
S15/NS1 RNA-binding domain0.0002995Direct
GroEL apical domain-like0.0005384Direct
"Winged helix" DNA-binding domain0.00789Inherited
F1F0 ATP synthase subunit C0.01231Inherited
Ribosomal proteins S24e, L23 and L15e0.01231Inherited
Translation proteins SH3-like domain0.01279Inherited
Activating enzymes of the ubiquitin-like proteins0.01508Inherited
Class II aaRS and biotin synthetases0.02531Inherited
L30e-like0.03758Inherited
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0.04283Inherited
Translational machinery components0.04283Inherited
Nucleotidylyl transferase0.04422Inherited
TPR-like0.04723Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.07255Inherited
Ribosomal protein S5 domain 2-like0.1101Inherited
Histone-fold0.1348Inherited
Translation proteins0.1426Inherited
SNARE-like0.2409Inherited
Cyclin-like0.3023Inherited
Protein kinase-like (PK-like)0.9873Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Smc hinge domain0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Group II chaperonin (CCT, TRIC), intermediate domain0Direct
Proteasome subunits0Direct
LEM domain0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Group II chaperonin (CCT, TRIC), ATPase domain0.000000004692Direct
BTB/POZ domain0.00000001676Direct
Skp1 dimerisation domain-like0.00000005216Direct
Extended AAA-ATPase domain0.0000001427Direct
RecA protein-like (ATPase-domain)0.0000006955Direct
Group II chaperonin (CCT, TRIC), apical domain0.00006551Direct
Cdc48 domain 2-like0.0000975Direct
Anticodon-binding domain0.0000975Direct
Cdc48 N-terminal domain-like0.0000975Direct
Sm motif of small nuclear ribonucleoproteins, SNRNP0.0002339Direct
Single strand DNA-binding domain, SSB0.0008287Direct
Motor proteins0.001708Inherited
F1F0 ATP synthase subunit C0.01009Inherited
DNA replication initiator (cdc21/cdc54) N-terminal domain0.0125Inherited
Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain0.02139Inherited
Elongation factors0.02654Inherited
Cold shock DNA-binding domain-like0.02945Inherited
Translational machinery components0.03204Inherited
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0.03647Inherited
L30e/L7ae ribosomal proteins0.03647Inherited
Nucleosome core histones0.0628Inherited
Nitrogenase iron protein-like0.08049Inherited
Clathrin adaptor core protein0.1401Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.1401Inherited
Class I aminoacyl-tRNA synthetases (RS), catalytic domain0.1586Inherited
Cyclin0.2201Inherited
Tetratricopeptide repeat (TPR)0.383Inherited
Protein serine/threonine phosphatase0.4374Inherited
Protein kinases, catalytic subunit0.973Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
LEM domain0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
The spindle assembly checkpoint protein mad20Direct
Smc hinge domain0Direct
Skp1 dimerisation domain-like0.00000005427Direct
P-loop containing nucleoside triphosphate hydrolases0.0000000672Direct
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.000000179Direct
Nucleic acid-binding proteins0.000005434Direct
Cdc48 domain 2-like0.00005489Direct
ADC-like0.00005489Direct
GroEL equatorial domain-like0.00006965Direct
GroEL-intermediate domain like0.00006965Direct
Sm-like ribonucleoproteins0.0001386Direct
POZ domain0.000155Direct
S15/NS1 RNA-binding domain0.0002466Direct
GroEL apical domain-like0.0004458Direct
"Winged helix" DNA-binding domain0.006748Inherited
F1F0 ATP synthase subunit C0.01063Inherited
Ribosomal proteins S24e, L23 and L15e0.01063Inherited
Translation proteins SH3-like domain0.01104Inherited
Activating enzymes of the ubiquitin-like proteins0.01306Inherited
Class II aaRS and biotin synthetases0.02214Inherited
L30e-like0.03313Inherited
Translational machinery components0.03782Inherited
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0.03782Inherited
Nucleotidylyl transferase0.03908Inherited
TPR-like0.04178Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.06489Inherited
Ribosomal protein S5 domain 2-like0.09962Inherited
Histone-fold0.1227Inherited
Translation proteins0.13Inherited
SNARE-like0.2233Inherited
Cyclin-like0.2832Inherited
Protein kinase-like (PK-like)0.9763Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
56091,50249
  • 56091 - DNA ligase/mRNA capping enzyme, catalytic domain
  • 50249 - Nucleic acid-binding proteins
  • 0Direct
    52540,47917
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase
  • 0Direct
    54585,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    50692,54585
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 0Direct
    54695,81382
  • 54695 - POZ domain
  • 81382 - Skp1 dimerisation domain-like
  • 0.000000179Direct
    81333,81333
  • 81333 - F1F0 ATP synthase subunit C
  • 81333 - F1F0 ATP synthase subunit C
  • 0.00005489Direct
    48592,54849
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 0.00006965Direct
    54849,52029
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.00006965Direct
    50249,55681
  • 50249 - Nucleic acid-binding proteins
  • 55681 - Class II aaRS and biotin synthetases
  • 0.0002466Direct
    52374,47323
  • 52374 - Nucleotidylyl transferase
  • 47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
  • 0.01063Inherited
    52540,50447
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 0.02743Inherited
    50447,50465
  • 50447 - Translation proteins
  • 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
  • 0.03782Inherited
    52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.05912Inherited
    48452,48452
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 0.09281Inherited
    48371,48371
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 0.2832Inherited
    47954,47954
  • 47954 - Cyclin-like
  • 47954 - Cyclin-like
  • 0.3786Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.6242Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    50692,54585,52540
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    54585,52540,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    48592,54849,52029
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.00006965Direct
    52540,50447,50465
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
  • 0.03782Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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