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Worm Phenotype (WP): germ cell development variant

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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)

Shortest distance to current term (+ for parents, - for children) WP term [WP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   Variant [WBPhenotype:0000886] <4>
+ + + 3:   development variant [WBPhenotype:0000518] <7>(506|577) (506|246|68)
+ + 2:   cell development variant [WBPhenotype:0000529] <17>(128|124) (129|49|15)
+ 1:   gametogenesis variant [WBPhenotype:0000774] <2>(65|59) (66|27|6)
0:   germ cell development variant [WBPhenotype:0000812] <8>(63|59) (64|27|6)
- 1:   meiosis defective early emb [WBPhenotype:0001041] <11>(38|34) (38|16|4)
- 1:   meiosis variant [WBPhenotype:0000775] <11>(38|34) (38|16|4)
- 1:   germline proliferation variant [WBPhenotype:0000823] <6>(6|5) (7|0|0)
- 1:   oogenesis variant [WBPhenotype:0000186] <5>(32|33) (32|14|2)
- 1:   no germ line [WBPhenotype:0000215] <2>(7|9) (7|3|1)
- 1:   distal germline variant [WBPhenotype:0000288](0|1) (0|0|0)
- 1:   feminization of germline [WBPhenotype:0000682](1|0) (1|0|0)
- 1:   masculinization of germline [WBPhenotype:0000683](1|2) (1|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Smc hinge domain0Direct
The spindle assembly checkpoint protein mad20Direct
GroEL equatorial domain-like0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Helical domain of Sec23/240Direct
Ribosomal protein L10Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Zn-finger domain of Sec23/240Direct
LEM domain0Direct
Ribosomal protein L10-like0Direct
GroEL-intermediate domain like0Direct
C-terminal, gelsolin-like domain of Sec23/240Direct
14-3-3 protein0Direct
Skp1 dimerisation domain-like0.000000000001251Direct
"Winged helix" DNA-binding domain0.0000000002033Direct
GroEL apical domain-like0.000000001332Direct
Nucleic acid-binding proteins0.000000007927Direct
Sm-like ribonucleoproteins0.000000009373Direct
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.00000002169Direct
WD40 repeat-like0.000001474Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase0.000007199Direct
Class II aaRS and biotin synthetases0.000008401Direct
Class II aaRS ABD-related0.0001505Direct
HMG-box0.0001766Direct
Histone-fold0.0002357Direct
Translation proteins SH3-like domain0.0003394Direct
Heat shock protein 70kD (HSP70), peptide-binding domain0.0003913Direct
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.0003913Direct
L30e-like0.0003913Direct
RBP11-like subunits of RNA polymerase0.0004875Direct
beta-sandwich domain of Sec23/240.0004875Direct
DNA repair protein MutS, domain III0.0004875Direct
Cdc48 domain 2-like0.0004875Direct
ADC-like0.0004875Direct
Heat shock protein 70kD (HSP70), C-terminal subdomain0.0008479Direct
Cullin homology domain0.0009187Direct
Nucleotidylyl transferase0.0009408Direct
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.001623Inherited
Retrovirus zinc finger-like domains0.001845Inherited
Ribosomal proteins S24e, L23 and L15e0.002042Inherited
F1F0 ATP synthase subunit C0.002042Inherited
S15/NS1 RNA-binding domain0.002042Inherited
Activating enzymes of the ubiquitin-like proteins0.002114Inherited
TPR-like0.002209Inherited
POZ domain0.002534Inherited
Ribosomal protein S5 domain 2-like0.005147Inherited
Translational machinery components0.005209Inherited
SMAD MH1 domain0.005209Inherited
SNARE-like0.007025Inherited
FKBP-like0.007138Inherited
Quinoprotein alcohol dehydrogenase-like0.008566Inherited
ACP-like0.01045Inherited
Translation proteins0.01177Inherited
CCCH zinc finger0.01879Inherited
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0.02833Inherited
Cysteine-rich domain0.1321Inherited
SET domain0.1834Inherited
P-loop containing nucleoside triphosphate hydrolases0.1892Inherited
ARM repeat0.5852Inherited
EGF/Laminin0.8851Inherited
RNA-binding domain, RBD0.9878Inherited
F-box domain1Inherited
Protein kinase-like (PK-like)1Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Ribosomal protein L10Direct
LEM domain0Direct
C-terminal, gelsolin-like domain of Sec23/240Direct
Zn-finger domain of Sec23/240Direct
Helical domain of Sec23/240Direct
Group II chaperonin (CCT, TRIC), intermediate domain0Direct
beta-sandwich domain of Sec23/240Direct
Group II chaperonin (CCT, TRIC), ATPase domain0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Smc hinge domain0Direct
POU-specific domain0Direct
RNA-polymerase beta0Direct
Proteasome subunits0Direct
14-3-3 protein0Direct
Trunk domain of Sec23/240Direct
Skp1 dimerisation domain-like0.000000000002015Direct
Group II chaperonin (CCT, TRIC), apical domain0.00000002971Direct
BTB/POZ domain0.0000001027Direct
Sm motif of small nuclear ribonucleoproteins, SNRNP0.0000007358Direct
Extended AAA-ATPase domain0.0000008926Direct
WD40-repeat0.000004273Direct
Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain0.00000619Direct
Pumilio repeat0.00000745Direct
RecA protein-like (ATPase-domain)0.00001228Direct
L30e/L7ae ribosomal proteins0.00008963Direct
Actin/HSP700.0002087Direct
Nucleosome core histones0.0003045Direct
Cyclin0.0003946Direct
HMG-box0.0003946Direct
DNA replication initiator (cdc21/cdc54) N-terminal domain0.0004546Direct
G proteins0.0004696Direct
DNA gyrase/MutL, N-terminal domain0.0006426Direct
Anticodon-binding domain of Class II aaRS0.0006426Direct
Cdc48 N-terminal domain-like0.0006426Direct
DNA repair protein MutS, domain III0.0006426Direct
RNA editing terminal uridyl transferase 2, RET2, domain 20.0006426Direct
Anticodon-binding domain0.0006426Direct
Cdc48 domain 2-like0.0006426Direct
Class I aminoacyl-tRNA synthetases (RS), catalytic domain0.002279Inherited
F1F0 ATP synthase subunit C0.002702Inherited
SMAD domain0.003109Inherited
Translational machinery components0.003109Inherited
Retrovirus zinc finger-like domains0.003277Inherited
SMAD MH1 domain0.006927Inherited
FKBP immunophilin/proline isomerase0.01041Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.01041Inherited
Cold shock DNA-binding domain-like0.01275Inherited
Clathrin adaptor core protein0.01389Inherited
CCCH zinc finger0.03354Inherited
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0.03751Inherited
Elongation factors0.03993Inherited
Ubiquitin-related0.0592Inherited
Nitrogenase iron protein-like0.07489Inherited
Tetratricopeptide repeat (TPR)0.1113Inherited
Histone lysine methyltransferases0.12Inherited
Motor proteins0.924Inherited
Canonical RBD0.9999Inherited
Protein kinases, catalytic subunit1Inherited


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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
The spindle assembly checkpoint protein mad20Direct
GroEL-intermediate domain like0Direct
GroEL equatorial domain-like0Direct
14-3-3 protein0Direct
Ribosomal protein L10Direct
Ribosomal protein L10-like0Direct
Helical domain of Sec23/240Direct
C-terminal, gelsolin-like domain of Sec23/240Direct
Zn-finger domain of Sec23/240Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
LEM domain0Direct
Smc hinge domain0Direct
Skp1 dimerisation domain-like0.0000000000009923Direct
"Winged helix" DNA-binding domain0.0000000001622Direct
GroEL apical domain-like0.000000001066Direct
Nucleic acid-binding proteins0.000000006363Direct
Sm-like ribonucleoproteins0.000000007529Direct
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.00000001745Direct
WD40 repeat-like0.000001202Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase0.00000589Direct
Class II aaRS and biotin synthetases0.000006873Direct
Class II aaRS ABD-related0.0001243Direct
HMG-box0.0001459Direct
Histone-fold0.000195Direct
Translation proteins SH3-like domain0.0002815Direct
L30e-like0.0003249Direct
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.0003249Direct
Heat shock protein 70kD (HSP70), peptide-binding domain0.0003249Direct
beta-sandwich domain of Sec23/240.0004053Direct
RBP11-like subunits of RNA polymerase0.0004053Direct
DNA repair protein MutS, domain III0.0004053Direct
ADC-like0.0004053Direct
Cdc48 domain 2-like0.0004053Direct
Heat shock protein 70kD (HSP70), C-terminal subdomain0.0007097Direct
Cullin homology domain0.0007694Direct
Nucleotidylyl transferase0.0007882Direct
PAP/OAS1 substrate-binding domain0.0009416Direct
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.001365Inherited
Retrovirus zinc finger-like domains0.001553Inherited
S15/NS1 RNA-binding domain0.001722Inherited
F1F0 ATP synthase subunit C0.001722Inherited
Ribosomal proteins S24e, L23 and L15e0.001722Inherited
Activating enzymes of the ubiquitin-like proteins0.001784Inherited
TPR-like0.001865Inherited
POZ domain0.002143Inherited
Ribosomal protein S5 domain 2-like0.004386Inherited
Translational machinery components0.00444Inherited
SMAD MH1 domain0.00444Inherited
SNARE-like0.006012Inherited
FKBP-like0.006111Inherited
Quinoprotein alcohol dehydrogenase-like0.007359Inherited
ACP-like0.008997Inherited
Translation proteins0.01015Inherited
CCCH zinc finger0.01632Inherited
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0.02484Inherited
Cysteine-rich domain0.1203Inherited
SET domain0.1685Inherited
P-loop containing nucleoside triphosphate hydrolases0.174Inherited
ARM repeat0.5628Inherited
EGF/Laminin0.8695Inherited
RNA-binding domain, RBD0.9768Inherited
Protein kinase-like (PK-like)0.9985Inherited
F-box domain1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
54849,52029
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0Direct
    48592,54849
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 0Direct
    81811,82754
  • 81811 - Helical domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0Direct
    50692,54585
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 0Direct
    54585,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    52540,47917
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase
  • 0Direct
    82919,53300
  • 82919 - Zn-finger domain of Sec23/24
  • 53300 - vWA-like
  • 0Direct
    54695,81382
  • 54695 - POZ domain
  • 81382 - Skp1 dimerisation domain-like
  • 0.000000000001588Direct
    100920,100934
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
  • 0.0001243Direct
    53067,53067
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 0.0002812Direct
    81301,81631
  • 81301 - Nucleotidyltransferase
  • 81631 - PAP/OAS1 substrate-binding domain
  • 0.0002815Direct
    53067,100920
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 0.0003249Direct
    55681,52954
  • 55681 - Class II aaRS and biotin synthetases
  • 52954 - Class II aaRS ABD-related
  • 0.0004053Direct
    81333,81333
  • 81333 - F1F0 ATP synthase subunit C
  • 81333 - F1F0 ATP synthase subunit C
  • 0.0004053Direct
    48334,52540
  • 48334 - DNA repair protein MutS, domain III
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.0004053Direct
    52540,46785
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 46785 - "Winged helix" DNA-binding domain
  • 0.0004053Direct
    52374,47323
  • 52374 - Nucleotidylyl transferase
  • 47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
  • 0.0007694Direct
    54928,54928
  • 54928 - RNA-binding domain, RBD
  • 54928 - RNA-binding domain, RBD
  • 0.0009077Direct
    50249,55681
  • 50249 - Nucleic acid-binding proteins
  • 55681 - Class II aaRS and biotin synthetases
  • 0.001722Inherited
    54534,54534
  • 54534 - FKBP-like
  • 54534 - FKBP-like
  • 0.001722Inherited
    48371,48371
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 0.01247Inherited
    52540,50447
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 0.017Inherited
    50447,50465
  • 50447 - Translation proteins
  • 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
  • 0.02484Inherited
    47954,47954
  • 47954 - Cyclin-like
  • 47954 - Cyclin-like
  • 0.0293Inherited
    90229,90229
  • 90229 - CCCH zinc finger
  • 90229 - CCCH zinc finger
  • 0.06341Inherited
    52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.09751Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.9619Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    50692,54585,52540
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    54585,52540,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    48592,54849,52029
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0Direct
    53067,100920,100934
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
  • 0.0001243Direct
    53067,53067,100920
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 0.0003249Direct
    52540,50447,50465
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
  • 0.02484Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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