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Worm Phenotype (WP): germ cell development variant

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Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)

Shortest distance to current term (+ for parents, - for children) WP term [WP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   Variant [WBPhenotype:0000886] <5>
+ + + 3:   development variant [WBPhenotype:0000518] <4>(511|586) (511|253|70)
+ + 2:   cell development variant [WBPhenotype:0000529] <16>(118|121) (119|46|13)
+ 1:   gametogenesis variant [WBPhenotype:0000774] <2>(56|54) (57|22|5)
0:   germ cell development variant [WBPhenotype:0000812] <6>(45|42) (46|17|5)
- 1:   meiosis variant [WBPhenotype:0000775] <10>(33|29) (33|14|4)
- 1:   germline proliferation variant [WBPhenotype:0000823] <6>(6|5) (6|0|0)
- 1:   distal germline variant [WBPhenotype:0000288](0|1) (0|0|0)
- 1:   feminization of germline [WBPhenotype:0000682](1|0) (1|0|0)
- 1:   masculinization of germline [WBPhenotype:0000683](1|2) (1|0|0)
- 1:   no germ line [WBPhenotype:0000215](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
GroEL equatorial domain-like0Direct
LEM domain0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Ribosomal protein L10-like0Direct
The spindle assembly checkpoint protein mad20Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
GroEL-intermediate domain like0Direct
Smc hinge domain0Direct
Skp1 dimerisation domain-like0.00000000000007322Direct
Nucleic acid-binding proteins0.00000000003029Direct
GroEL apical domain-like0.0000000002399Direct
Sm-like ribonucleoproteins0.000000001113Direct
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.000000001761Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase0.000002614Direct
Translation proteins SH3-like domain0.0001158Direct
HMG-box0.0002306Direct
Cdc48 domain 2-like0.0002524Direct
ADC-like0.0002524Direct
RBP11-like subunits of RNA polymerase0.0002524Direct
S15/NS1 RNA-binding domain0.001088Inherited
Ribosomal proteins S24e, L23 and L15e0.001088Inherited
F1F0 ATP synthase subunit C0.001088Inherited
Nucleotidylyl transferase0.001713Inherited
L30e-like0.001965Inherited
Translational machinery components0.002841Inherited
SMAD MH1 domain0.002841Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.005693Inherited
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0.01648Inherited
Ribosomal protein S5 domain 2-like0.019Inherited
POZ domain0.03915Inherited
"Winged helix" DNA-binding domain0.03915Inherited
SET domain0.09873Inherited
ARM repeat0.1213Inherited
Histone-fold0.1292Inherited
P-loop containing nucleoside triphosphate hydrolases0.1939Inherited
EGF/Laminin0.2184Inherited
Translation proteins0.5898Inherited
SNARE-like0.7102Inherited
Activating enzymes of the ubiquitin-like proteins0.779Inherited
TPR-like0.7901Inherited
Protein kinase-like (PK-like)0.8183Inherited
Class II aaRS and biotin synthetases0.9184Inherited
F-box domain0.9543Inherited
Cysteine-rich domain0.9901Inherited
RNA-binding domain, RBD1Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
LEM domain0Direct
RNA-polymerase beta0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Proteasome subunits0Direct
Group II chaperonin (CCT, TRIC), intermediate domain0Direct
Group II chaperonin (CCT, TRIC), ATPase domain0Direct
Smc hinge domain0Direct
Skp1 dimerisation domain-like0.0000000000001171Direct
Group II chaperonin (CCT, TRIC), apical domain0.000000006403Direct
Sm motif of small nuclear ribonucleoproteins, SNRNP0.0000001436Direct
Pumilio repeat0.0000002777Direct
RecA protein-like (ATPase-domain)0.000004482Direct
Nucleosome core histones0.00002338Direct
DNA replication initiator (cdc21/cdc54) N-terminal domain0.0002028Direct
Actin/HSP700.0002695Direct
RNA editing terminal uridyl transferase 2, RET2, domain 20.0003325Direct
Anticodon-binding domain0.0003325Direct
Cdc48 N-terminal domain-like0.0003325Direct
Cdc48 domain 2-like0.0003325Direct
HMG-box0.0004659Direct
Single strand DNA-binding domain, SSB0.000559Direct
Cold shock DNA-binding domain-like0.0009874Direct
F1F0 ATP synthase subunit C0.001433Inherited
L30e/L7ae ribosomal proteins0.001433Inherited
SMAD domain0.00145Inherited
Translational machinery components0.00145Inherited
SMAD MH1 domain0.00377Inherited
Class I aminoacyl-tRNA synthetases (RS), catalytic domain0.004224Inherited
Clathrin adaptor core protein0.007717Inherited
Elongation factors0.01915Inherited
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0.02179Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.03238Inherited
Nitrogenase iron protein-like0.0453Inherited
Histone lysine methyltransferases0.06941Inherited
BTB/POZ domain0.07874Inherited
Extended AAA-ATPase domain0.1545Inherited
Motor proteins0.2971Inherited
Protein kinases, catalytic subunit0.8213Inherited
G proteins0.8287Inherited
Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain0.899Inherited
Canonical RBD1Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Ribosomal protein L10-like0Direct
GroEL-intermediate domain like0Direct
Smc hinge domain0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
GroEL equatorial domain-like0Direct
LEM domain0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
The spindle assembly checkpoint protein mad20Direct
Skp1 dimerisation domain-like0.00000000000005728Direct
Nucleic acid-binding proteins0.00000000002387Direct
GroEL apical domain-like0.0000000001895Direct
Sm-like ribonucleoproteins0.0000000008815Direct
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.000000001396Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase0.000002112Direct
Translation proteins SH3-like domain0.0000946Direct
HMG-box0.0001887Direct
RBP11-like subunits of RNA polymerase0.0002068Direct
Cdc48 domain 2-like0.0002068Direct
ADC-like0.0002068Direct
PAP/OAS1 substrate-binding domain0.0008895Direct
F1F0 ATP synthase subunit C0.0009019Direct
S15/NS1 RNA-binding domain0.0009019Direct
Ribosomal proteins S24e, L23 and L15e0.0009019Direct
Nucleotidylyl transferase0.001428Inherited
L30e-like0.001642Inherited
SMAD MH1 domain0.002388Inherited
Translational machinery components0.002388Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.004826Inherited
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0.01423Inherited
Ribosomal protein S5 domain 2-like0.01645Inherited
"Winged helix" DNA-binding domain0.03437Inherited
POZ domain0.03437Inherited
SET domain0.08877Inherited
ARM repeat0.1097Inherited
Histone-fold0.1172Inherited
P-loop containing nucleoside triphosphate hydrolases0.178Inherited
EGF/Laminin0.2016Inherited
Translation proteins0.5676Inherited
SNARE-like0.6898Inherited
Activating enzymes of the ubiquitin-like proteins0.7608Inherited
TPR-like0.7721Inherited
Protein kinase-like (PK-like)0.8015Inherited
Class II aaRS and biotin synthetases0.9057Inherited
F-box domain0.9433Inherited
Cysteine-rich domain0.98Inherited
RNA-binding domain, RBD1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
54585,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    50692,54585
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 0Direct
    52540,47917
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase
  • 0Direct
    54849,52029
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0Direct
    48592,54849
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 0Direct
    54695,81382
  • 54695 - POZ domain
  • 81382 - Skp1 dimerisation domain-like
  • 0.0000000000001065Direct
    81333,81333
  • 81333 - F1F0 ATP synthase subunit C
  • 81333 - F1F0 ATP synthase subunit C
  • 0.0002068Direct
    81301,81631
  • 81301 - Nucleotidyltransferase
  • 81631 - PAP/OAS1 substrate-binding domain
  • 0.0003302Direct
    100920,100934
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
  • 0.0008178Direct
    50249,55681
  • 50249 - Nucleic acid-binding proteins
  • 55681 - Class II aaRS and biotin synthetases
  • 0.0009019Direct
    55753,55753
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 0.0009019Direct
    52374,47323
  • 52374 - Nucleotidylyl transferase
  • 47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
  • 0.004945Inherited
    48371,48371
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 0.005575Inherited
    52540,50447
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 0.007735Inherited
    50447,50465
  • 50447 - Translation proteins
  • 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
  • 0.01423Inherited
    52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.06083Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.4646Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    50692,54585,52540
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    54585,52540,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    48592,54849,52029
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0Direct
    53067,100920,100934
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
  • 0.0008178Direct
    52540,50447,50465
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
  • 0.01423Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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