SUPERFAMILY 1.75 HMM library and genome assignments server

Superfamily is undergoing a server migration - you are now browsing on the new server. Please contact us if you experience any problems.

Worm Phenotype (WP): germ cell development variant

(show info)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)

Shortest distance to current term (+ for parents, - for children) WP term [WP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   Variant [WBPhenotype:0000886] <5>
+ + + 3:   development variant [WBPhenotype:0000518] <7>(511|586) (511|253|70)
+ + 2:   cell development variant [WBPhenotype:0000529] <16>(125|123) (125|48|16)
+ 1:   gametogenesis variant [WBPhenotype:0000774] <2>(64|59) (64|26|6)
0:   germ cell development variant [WBPhenotype:0000812] <8>(62|59) (62|26|6)
- 1:   meiosis defective early emb [WBPhenotype:0001041] <11>(37|33) (37|16|4)
- 1:   meiosis variant [WBPhenotype:0000775] <11>(37|33) (37|16|4)
- 1:   germline proliferation variant [WBPhenotype:0000823] <6>(6|5) (7|0|0)
- 1:   oogenesis variant [WBPhenotype:0000186] <5>(31|33) (31|14|2)
- 1:   no germ line [WBPhenotype:0000215] <2>(7|9) (7|3|1)
- 1:   distal germline variant [WBPhenotype:0000288](0|1) (0|0|0)
- 1:   feminization of germline [WBPhenotype:0000682](1|0) (1|0|0)
- 1:   masculinization of germline [WBPhenotype:0000683](1|2) (1|0|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
14-3-3 protein0Direct
Helical domain of Sec23/240Direct
Zn-finger domain of Sec23/240Direct
GroEL-intermediate domain like0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
GroEL equatorial domain-like0Direct
Ribosomal protein L10Direct
Smc hinge domain0Direct
Ribosomal protein L10-like0Direct
The spindle assembly checkpoint protein mad20Direct
LEM domain0Direct
C-terminal, gelsolin-like domain of Sec23/240Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Skp1 dimerisation domain-like0.000000000001041Direct
"Winged helix" DNA-binding domain0.0000000001443Direct
GroEL apical domain-like0.000000001206Direct
Nucleic acid-binding proteins0.000000006224Direct
Sm-like ribonucleoproteins0.000000008217Direct
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.00000001848Direct
WD40 repeat-like0.0000003781Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase0.000006871Direct
Class II aaRS and biotin synthetases0.000007612Direct
HMG-box0.00009284Direct
Class II aaRS ABD-related0.0001435Direct
Histone-fold0.0001988Direct
Translation proteins SH3-like domain0.0003205Direct
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.000373Direct
Heat shock protein 70kD (HSP70), peptide-binding domain0.000373Direct
L30e-like0.000373Direct
beta-sandwich domain of Sec23/240.000474Direct
ADC-like0.000474Direct
Cdc48 domain 2-like0.000474Direct
RBP11-like subunits of RNA polymerase0.000474Direct
DNA repair protein MutS, domain III0.000474Direct
Heat shock protein 70kD (HSP70), C-terminal subdomain0.00081Direct
Cullin homology domain0.0008859Direct
Nucleotidylyl transferase0.001218Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.001553Inherited
F1F0 ATP synthase subunit C0.001993Inherited
S15/NS1 RNA-binding domain0.001993Inherited
Ribosomal proteins S24e, L23 and L15e0.001993Inherited
Activating enzymes of the ubiquitin-like proteins0.002043Inherited
TPR-like0.002225Inherited
POZ domain0.002823Inherited
SMAD MH1 domain0.005091Inherited
Translational machinery components0.005091Inherited
Retrovirus zinc finger-like domains0.005853Inherited
Ribosomal protein S5 domain 2-like0.005933Inherited
SNARE-like0.006753Inherited
FKBP-like0.006921Inherited
Quinoprotein alcohol dehydrogenase-like0.008164Inherited
Translation proteins0.01116Inherited
CCCH zinc finger0.0179Inherited
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0.02771Inherited
Cysteine-rich domain0.1277Inherited
SET domain0.1778Inherited
P-loop containing nucleoside triphosphate hydrolases0.188Inherited
ARM repeat0.6034Inherited
EGF/Laminin0.8997Inherited
RNA-binding domain, RBD1Inherited
Protein kinase-like (PK-like)1Inherited
F-box domain1Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
POU-specific domain0Direct
Trunk domain of Sec23/240Direct
beta-sandwich domain of Sec23/240Direct
Ribosomal protein L10Direct
Helical domain of Sec23/240Direct
14-3-3 protein0Direct
Group II chaperonin (CCT, TRIC), ATPase domain0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Group II chaperonin (CCT, TRIC), intermediate domain0Direct
Proteasome subunits0Direct
Smc hinge domain0Direct
RNA-polymerase beta0Direct
C-terminal, gelsolin-like domain of Sec23/240Direct
LEM domain0Direct
Zn-finger domain of Sec23/240Direct
Skp1 dimerisation domain-like0.000000000001869Direct
Group II chaperonin (CCT, TRIC), apical domain0.00000002888Direct
BTB/POZ domain0.00000009271Direct
Sm motif of small nuclear ribonucleoproteins, SNRNP0.0000007115Direct
Extended AAA-ATPase domain0.0000008299Direct
WD40-repeat0.000001258Direct
Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain0.000005965Direct
RecA protein-like (ATPase-domain)0.00001214Direct
Pumilio repeat0.00002307Direct
L30e/L7ae ribosomal proteins0.0000893Direct
Actin/HSP700.0002024Direct
HMG-box0.0002228Direct
Nucleosome core histones0.0002853Direct
Cyclin0.0003861Direct
G proteins0.0004293Direct
DNA replication initiator (cdc21/cdc54) N-terminal domain0.0004524Direct
Cdc48 N-terminal domain-like0.0006422Direct
RNA editing terminal uridyl transferase 2, RET2, domain 20.0006422Direct
Cdc48 domain 2-like0.0006422Direct
DNA repair protein MutS, domain III0.0006422Direct
Anticodon-binding domain0.0006422Direct
Anticodon-binding domain of Class II aaRS0.0006422Direct
DNA gyrase/MutL, N-terminal domain0.0006422Direct
Class I aminoacyl-tRNA synthetases (RS), catalytic domain0.00224Inherited
F1F0 ATP synthase subunit C0.002698Inherited
Translational machinery components0.003086Inherited
SMAD domain0.003086Inherited
SMAD MH1 domain0.006901Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.01035Inherited
FKBP immunophilin/proline isomerase0.01035Inherited
Retrovirus zinc finger-like domains0.01047Inherited
Cold shock DNA-binding domain-like0.01253Inherited
Clathrin adaptor core protein0.01385Inherited
CCCH zinc finger0.03302Inherited
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0.03743Inherited
Elongation factors0.03955Inherited
Ubiquitin-related0.05837Inherited
Nitrogenase iron protein-like0.0747Inherited
Tetratricopeptide repeat (TPR)0.1098Inherited
Histone lysine methyltransferases0.1197Inherited
Motor proteins0.9419Inherited
Protein kinases, catalytic subunit1Inherited
Canonical RBD1Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
Plot tree as:   Download Newick format tree:
(show help)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
GroEL equatorial domain-like0Direct
Ribosomal protein L10Direct
Zn-finger domain of Sec23/240Direct
LEM domain0Direct
Helical domain of Sec23/240Direct
14-3-3 protein0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
GroEL-intermediate domain like0Direct
Smc hinge domain0Direct
Ribosomal protein L10-like0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
The spindle assembly checkpoint protein mad20Direct
C-terminal, gelsolin-like domain of Sec23/240Direct
Skp1 dimerisation domain-like0.0000000000008125Direct
"Winged helix" DNA-binding domain0.0000000001134Direct
GroEL apical domain-like0.0000000009506Direct
Nucleic acid-binding proteins0.000000004924Direct
Sm-like ribonucleoproteins0.000000006505Direct
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.00000001465Direct
WD40 repeat-like0.0000003021Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase0.000005546Direct
Class II aaRS and biotin synthetases0.000006144Direct
HMG-box0.00007563Direct
Class II aaRS ABD-related0.0001171Direct
Histone-fold0.0001624Direct
Translation proteins SH3-like domain0.0002627Direct
Heat shock protein 70kD (HSP70), peptide-binding domain0.0003059Direct
L30e-like0.0003059Direct
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.0003059Direct
DNA repair protein MutS, domain III0.0003897Direct
RBP11-like subunits of RNA polymerase0.0003897Direct
Cdc48 domain 2-like0.0003897Direct
ADC-like0.0003897Direct
beta-sandwich domain of Sec23/240.0003897Direct
Heat shock protein 70kD (HSP70), C-terminal subdomain0.0006689Direct
Cullin homology domain0.0007321Direct
Nucleotidylyl transferase0.00101Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.001291Inherited
S15/NS1 RNA-binding domain0.00166Inherited
Ribosomal proteins S24e, L23 and L15e0.00166Inherited
F1F0 ATP synthase subunit C0.00166Inherited
Activating enzymes of the ubiquitin-like proteins0.001703Inherited
TPR-like0.001857Inherited
POZ domain0.002365Inherited
Translational machinery components0.0043Inherited
SMAD MH1 domain0.0043Inherited
Retrovirus zinc finger-like domains0.004951Inherited
Ribosomal protein S5 domain 2-like0.00502Inherited
SNARE-like0.005723Inherited
FKBP-like0.005869Inherited
Quinoprotein alcohol dehydrogenase-like0.006946Inherited
Translation proteins0.009542Inherited
CCCH zinc finger0.01543Inherited
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0.02417Inherited
Cysteine-rich domain0.1158Inherited
SET domain0.1628Inherited
P-loop containing nucleoside triphosphate hydrolases0.1722Inherited
ARM repeat0.5811Inherited
EGF/Laminin0.8854Inherited
RNA-binding domain, RBD0.9938Inherited
F-box domain1Inherited
Protein kinase-like (PK-like)1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
48592,54849
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 0Direct
    50692,54585
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 0Direct
    54849,52029
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0Direct
    81811,82754
  • 81811 - Helical domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0Direct
    82919,53300
  • 82919 - Zn-finger domain of Sec23/24
  • 53300 - vWA-like
  • 0Direct
    52540,47917
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase
  • 0Direct
    54585,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    54695,81382
  • 54695 - POZ domain
  • 81382 - Skp1 dimerisation domain-like
  • 0.000000000001316Direct
    100920,100934
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
  • 0.0001171Direct
    53067,53067
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 0.0002517Direct
    53067,100920
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 0.0003059Direct
    48334,52540
  • 48334 - DNA repair protein MutS, domain III
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.0003897Direct
    52540,46785
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 46785 - "Winged helix" DNA-binding domain
  • 0.0003897Direct
    81333,81333
  • 81333 - F1F0 ATP synthase subunit C
  • 81333 - F1F0 ATP synthase subunit C
  • 0.0003897Direct
    55681,52954
  • 55681 - Class II aaRS and biotin synthetases
  • 52954 - Class II aaRS ABD-related
  • 0.0003897Direct
    52374,47323
  • 52374 - Nucleotidylyl transferase
  • 47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
  • 0.0007321Direct
    81301,81631
  • 81301 - Nucleotidyltransferase
  • 81631 - PAP/OAS1 substrate-binding domain
  • 0.0008804Direct
    50249,55681
  • 50249 - Nucleic acid-binding proteins
  • 55681 - Class II aaRS and biotin synthetases
  • 0.00166Inherited
    54534,54534
  • 54534 - FKBP-like
  • 54534 - FKBP-like
  • 0.00166Inherited
    48371,48371
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 0.0119Inherited
    52540,50447
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 0.01628Inherited
    50447,50465
  • 50447 - Translation proteins
  • 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
  • 0.02417Inherited
    47954,47954
  • 47954 - Cyclin-like
  • 47954 - Cyclin-like
  • 0.02829Inherited
    90229,90229
  • 90229 - CCCH zinc finger
  • 90229 - CCCH zinc finger
  • 0.06153Inherited
    52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.06934Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.978Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    48592,54849,52029
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0Direct
    50692,54585,52540
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    54585,52540,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    53067,100920,100934
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
  • 0.0001171Direct
    53067,53067,100920
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 0.0003059Direct
    52540,50447,50465
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
  • 0.02417Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)