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Worm Phenotype (WP): level of transgene expression variant

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Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)

Shortest distance to current term (+ for parents, - for children) WP term [WP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + + + 7:   Variant [WBPhenotype:0000886] <2>
+ + + + + + 6:   physiology variant [WBPhenotype:0000519] <14>(510|587) (510|248|68)
+ + + + + 5:   organism physiology variant [WBPhenotype:0000576] <9>(369|431) (372|193|56)
+ + + + 4:   organism homeostasis metabolism variant [WBPhenotype:0000577] <16>(361|421) (363|190|55)
+ + + 3:   organism metabolism processing variant [WBPhenotype:0000027] <25>(178|190) (182|87|26)
+ + 2:   gene expression variant [WBPhenotype:0000717] <11>(127|139) (131|64|20)
+ 1:   transgene expression variant [WBPhenotype:0000306] <3>(82|99) (85|43|14)
0:   level of transgene expression variant [WBPhenotype:0000962] <2>(36|44) (39|12|5)
- 1:   transgene expression reduced [WBPhenotype:0001278] <3>(12|14) (12|2|2)
- 1:   transgene expression increased [WBPhenotype:0001236](15|22) (15|8|3)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
F1F0 ATP synthase subunit C0Direct
FF domain0Direct
TK C-terminal domain-like0Direct
Cytochrome c0Direct
GroEL-intermediate domain like0Direct
GroEL equatorial domain-like0Direct
Heme-dependent catalase-like0Direct
14-3-3 protein0Direct
Ribosomal protein L10Direct
ValRS/IleRS/LeuRS editing domain0Direct
Epsilon subunit of mitochondrial F1F0-ATP synthase0Direct
HSP90 C-terminal domain0Direct
GroEL apical domain-like0.00000001805Direct
Homeodomain-like0.0000001661Direct
Glucocorticoid receptor-like (DNA-binding domain)0.0000002882Direct
Saposin0.000006782Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase0.00003339Direct
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.00007662Direct
Single hybrid motif0.00007662Direct
Leucine zipper domain0.00009024Direct
Zn-binding ribosomal proteins0.0001928Direct
ClpP/crotonase0.0002057Direct
Nuclear receptor ligand-binding domain0.0008344Direct
ADC-like0.001323Inherited
Cdc48 domain 2-like0.001323Inherited
Protein kinase-like (PK-like)0.00355Inherited
Tubby C-terminal domain-like0.005304Inherited
S15/NS1 RNA-binding domain0.005304Inherited
Nucleotidylyl transferase0.02074Inherited
SMAD MH1 domain0.0524Inherited
4Fe-4S ferredoxins0.1542Inherited
Frizzled cysteine-rich domain0.1542Inherited
S-adenosylmethionine synthetase0.1542Inherited
PYP-like sensor domain (PAS domain)0.2526Inherited
Class II aaRS ABD-related0.3236Inherited
Heat shock protein 70kD (HSP70), C-terminal subdomain0.6351Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
CAT-like0Direct
Ribosomal protein L10Direct
a tRNA synthase domain0Direct
Heat shock protein 90, HSP90, N-terminal domain0Direct
ValRS/IleRS/LeuRS editing domain0Direct
Heme-dependent catalases0Direct
Epsilon subunit of mitochondrial F1F0-ATP synthase0Direct
FF domain0Direct
Hsp90 middle domain0Direct
Group II chaperonin (CCT, TRIC), intermediate domain0Direct
Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain0Direct
RNA-polymerase beta0Direct
14-3-3 protein0Direct
HSP90 C-terminal domain0Direct
Group II chaperonin (CCT, TRIC), ATPase domain0Direct
F1F0 ATP synthase subunit C0Direct
Anticodon-binding domain of Class II aaRS0Direct
Group II chaperonin (CCT, TRIC), apical domain0.0000004493Direct
Homeodomain0.000003612Direct
Biotinyl/lipoyl-carrier proteins and domains0.0002192Direct
Transforming growth factor (TGF)-beta0.0003908Direct
Leucine zipper domain0.0004108Direct
Dual specificity phosphatase-like0.0005378Direct
Proteasome subunits0.0005378Direct
Cyclin0.0007226Direct
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.0008629Direct
Cdc48 domain 2-like0.002061Inherited
Anticodon-binding domain0.002061Inherited
Biotin dependent carboxylase carboxyltransferase domain0.002061Inherited
MIF4G domain-like0.002061Inherited
Cdc48 N-terminal domain-like0.002061Inherited
DEP domain0.008219Inherited
Nuclear receptor0.0183Inherited
SMAD domain0.0281Inherited
Class I aminoacyl-tRNA synthetases (RS), catalytic domain0.04806Inherited
SMAD MH1 domain0.04886Inherited
Nuclear receptor ligand-binding domain0.059Inherited
Protein kinases, catalytic subunit0.1193Inherited
Frizzled cysteine-rich domain0.1444Inherited
S-adenosylmethionine synthetase0.1444Inherited
PDI-like0.2436Inherited
RecA protein-like (ATPase-domain)0.2436Inherited
PLC-like (P variant)0.4813Inherited
Heat shock protein 70kD (HSP70), C-terminal subdomain0.6335Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
F1F0 ATP synthase subunit C0Direct
GroEL equatorial domain-like0Direct
Epsilon subunit of mitochondrial F1F0-ATP synthase0Direct
ValRS/IleRS/LeuRS editing domain0Direct
Heme-dependent catalase-like0Direct
14-3-3 protein0Direct
HSP90 C-terminal domain0Direct
Ribosomal protein L10Direct
GroEL-intermediate domain like0Direct
FF domain0Direct
Cytochrome c0Direct
TK C-terminal domain-like0Direct
GroEL apical domain-like0.00000001441Direct
Homeodomain-like0.0000001333Direct
Glucocorticoid receptor-like (DNA-binding domain)0.0000002318Direct
Saposin0.000005516Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase0.00002727Direct
Single hybrid motif0.0000627Direct
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.0000627Direct
Leucine zipper domain0.00007392Direct
Zn-binding ribosomal proteins0.0001583Direct
ClpP/crotonase0.000169Direct
Nuclear receptor ligand-binding domain0.000694Direct
Cyclin-like0.0008355Direct
p53-like transcription factors0.0008355Direct
Histone-fold0.0009359Direct
Cdc48 domain 2-like0.001104Inherited
ADC-like0.001104Inherited
Protein kinase-like (PK-like)0.003004Inherited
Tubby C-terminal domain-like0.004509Inherited
S15/NS1 RNA-binding domain0.004509Inherited
Nucleotidylyl transferase0.01806Inherited
SMAD MH1 domain0.0465Inherited
S-adenosylmethionine synthetase0.1408Inherited
4Fe-4S ferredoxins0.1408Inherited
Frizzled cysteine-rich domain0.1408Inherited
PYP-like sensor domain (PAS domain)0.2347Inherited
Class II aaRS ABD-related0.3041Inherited
Heat shock protein 70kD (HSP70), C-terminal subdomain0.6132Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
50677,52374
  • 50677 - ValRS/IleRS/LeuRS editing domain
  • 52374 - Nucleotidylyl transferase
  • 0Direct
    48592,54849
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 0Direct
    81333,81333
  • 81333 - F1F0 ATP synthase subunit C
  • 81333 - F1F0 ATP synthase subunit C
  • 0Direct
    54849,52029
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0Direct
    52518,52922
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 52922 - TK C-terminal domain-like
  • 0Direct
    81698,81698
  • 81698 - FF domain
  • 81698 - FF domain
  • 0Direct
    54585,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    50692,54585
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 0Direct
    50249,55681
  • 50249 - Nucleic acid-binding proteins
  • 55681 - Class II aaRS and biotin synthetases
  • 0.004509Inherited
    55681,52954
  • 55681 - Class II aaRS and biotin synthetases
  • 52954 - Class II aaRS ABD-related
  • 0.1408Inherited
    55973,55973
  • 55973 - S-adenosylmethionine synthetase
  • 55973 - S-adenosylmethionine synthetase
  • 0.1408Inherited
    100920,100934
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
  • 0.5872Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    50692,54585,52540
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    54585,52540,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    48592,54849,52029
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0Direct
    55973,55973,55973
  • 55973 - S-adenosylmethionine synthetase
  • 55973 - S-adenosylmethionine synthetase
  • 55973 - S-adenosylmethionine synthetase
  • 0.1408Inherited
    53067,100920,100934
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
  • 0.5872Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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