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Worm Phenotype (WP): blast cell physiology variant

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Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)

Shortest distance to current term (+ for parents, - for children) WP term [WP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + 2:   Variant [WBPhenotype:0000886] <4>
+ 1:   physiology variant [WBPhenotype:0000519] <7>(489|563) (489|241|65)
0:   blast cell physiology variant [WBPhenotype:0000985] <26>(152|154) (153|67|17)
- 1:   cell division variant [WBPhenotype:0000746] <20>(55|57) (55|24|4)
- 1:   cell homeostasis metabolism variant [WBPhenotype:0000585] <12>(65|61) (65|26|11)
- 1:   muscle cell physiology variant [WBPhenotype:0000990] <7>(18|20) (19|12|4)
- 1:   neuron physiology variant [WBPhenotype:0000991] <7>(4|5) (4|1|0)
- 1:   cell secretion variant [WBPhenotype:0000258] <6>(7|7) (7|0|0)
- 1:   cell cycle variant [WBPhenotype:0000740] <5>(8|10) (8|4|1)
- 1:   calcium mediated signaling variant [WBPhenotype:0002170] <4>(0|0) (0|0|0)
- 1:   germ cell physiology variant [WBPhenotype:0000987] <4>(7|5) (7|0|0)
- 1:   nuclear positioning variant [WBPhenotype:0000511] <4>(12|14) (13|5|1)
- 1:   cell death variant [WBPhenotype:0000729] <3>(57|51) (58|17|5)
- 1:   cell membrane physiology variant [WBPhenotype:0001965] <3>(0|0) (0|0|0)
- 1:   membrane trafficking variant [WBPhenotype:0001833] <3>(4|3) (4|1|0)
- 1:   oocyte physiology variant [WBPhenotype:0001424] <3>(14|14) (15|7|1)
- 1:   endocytic transport variant [WBPhenotype:0001421] <2>(28|26) (29|11|2)
- 1:   epithelial cell physiology variant [WBPhenotype:0000986] <2>(3|3) (3|2|1)
- 1:   vesicle trafficking variant [WBPhenotype:0001752] <2>(1|0) (1|0|0)
- 1:   coelomocyte physiology variant [WBPhenotype:0001423] <1>(7|7) (7|2|0)
- 1:   embryonic cell physiology variant [WBPhenotype:0000763] <1>(13|17) (13|7|0)
- 1:   lysosome homeostasis deficient [WBPhenotype:0001784] <1>(0|0) (0|0|0)
- 1:   lysosome organization biogenesis variant [WBPhenotype:0001430] <1>(3|3) (3|2|2)
- 1:   nuclear division variant [WBPhenotype:0000504] <1>(7|8) (7|4|2)
- 1:   plasma membrane composition variant [WBPhenotype:0002177] <1>(4|1) (4|1|1)
- 1:   cell growth variant [WBPhenotype:0010001](0|0) (0|0|0)
- 1:   gland cell physiology variant [WBPhenotype:0000988](0|0) (0|0|0)
- 1:   marginal cell physiology variant [WBPhenotype:0000989](0|0) (0|0|0)
- 1:   peroxisome physiology variant [WBPhenotype:0001264](0|0) (0|0|0)


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Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Lipovitellin-phosvitin complex, superhelical domain0Direct
HSP90 C-terminal domain0Direct
RBP11-like subunits of RNA polymerase0Direct
Smc hinge domain0Direct
Ribosomal protein S100Direct
Lesion bypass DNA polymerase (Y-family), little finger domain0Direct
ARM repeat0Direct
DNA repair protein MutS, domain III0Direct
DNA ligase/mRNA capping enzyme, catalytic domain0Direct
Helical domain of Sec23/240Direct
14-3-3 protein0Direct
LEM domain0Direct
The spindle assembly checkpoint protein mad20Direct
C-terminal, gelsolin-like domain of Sec23/240Direct
VPS9 domain0Direct
Profilin (actin-binding protein)0Direct
Cullin homology domain0Direct
Lipovitellin-phosvitin complex; beta-sheet shell regions0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
PX domain0Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0Direct
Restriction endonuclease-like0Direct
5' to 3' exonuclease, C-terminal subdomain0Direct
Clathrin adaptor appendage domain0Direct
ValRS/IleRS/LeuRS editing domain0Direct
Subdomain of clathrin and coatomer appendage domain0Direct
Sec7 domain0Direct
Ribosomal protein L10-like0Direct
Zn-finger domain of Sec23/240Direct
DLC0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
P-loop containing nucleoside triphosphate hydrolases0Direct
Ribosomal protein L10Direct
Histone-fold8.891e-16Direct
Nicotinic receptor ligand binding domain-like0.0000000000009126Direct
Nucleic acid-binding proteins0.000000000002936Direct
Neurotransmitter-gated ion-channel transmembrane pore0.0000000000178Direct
"Winged helix" DNA-binding domain0.00000000002151Direct
Skp1 dimerisation domain-like0.00000000009069Direct
PH domain-like0.0000000002213Direct
WD40 repeat-like0.000000004651Direct
FYVE/PHD zinc finger0.0000004662Direct
GroEL apical domain-like0.000004176Direct
Translation proteins SH3-like domain0.000009638Direct
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.00001099Direct
SNARE-like0.00001413Direct
t-snare proteins0.0000158Direct
GroEL equatorial domain-like0.0000158Direct
GroEL-intermediate domain like0.0000158Direct
C2 domain (Calcium/lipid-binding domain, CaLB)0.00001611Direct
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.00003346Direct
Translation proteins0.00003411Direct
SH3-domain0.00004574Direct
Activating enzymes of the ubiquitin-like proteins0.00005934Direct
Calponin-homology domain, CH-domain0.0001167Direct
ENTH/VHS domain0.0001579Direct
Actin-like ATPase domain0.0001746Direct
Cyclin-like0.0002769Direct
HLH, helix-loop-helix DNA-binding domain0.0002897Direct
Tubulin C-terminal domain-like0.0003849Direct
Lamin A/C globular tail domain0.0004576Direct
Spectrin repeat0.0004576Direct
Ribosomal protein S5 domain 2-like0.0006128Direct
Sec1/munc18-like (SM) proteins0.0008113Direct
Clc chloride channel0.0008113Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase0.0008113Direct
Tubulin nucleotide-binding domain-like0.001019Inherited
DNA/RNA polymerases0.00119Inherited
Calpain large subunit, middle domain (domain III)0.001258Inherited
Prefoldin0.001258Inherited
PIN domain-like0.001258Inherited
Class II aaRS ABD-related0.001258Inherited
Nucleotidylyl transferase0.001436Inherited
RNA-binding domain, RBD0.002144Inherited
Ribosomal proteins S24e, L23 and L15e0.002936Inherited
CAD & PB1 domains0.002936Inherited
Frizzled cysteine-rich domain0.002936Inherited
F1F0 ATP synthase subunit C0.002936Inherited
Class II aaRS and biotin synthetases0.003129Inherited
Intermediate filament protein, coiled coil region0.003705Inherited
Sm-like ribonucleoproteins0.004021Inherited
DBL homology domain (DH-domain)0.004021Inherited
DEATH domain0.004081Inherited
Cullin repeat-like0.004081Inherited
L30e-like0.004081Inherited
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0.004081Inherited
Growth factor receptor domain0.005021Inherited
Metal cation-transporting ATPase, ATP-binding domain N0.005363Inherited
Protein kinase-like (PK-like)0.005624Inherited
Ubiquitin-like0.006824Inherited
GTPase activation domain, GAP0.007692Inherited
TPR-like0.007707Inherited
BAR/IMD domain-like0.007721Inherited
Calcium ATPase, transmembrane domain M0.008729Inherited
Hedgehog/intein (Hint) domain0.009848Inherited
SET domain0.01008Inherited
beta-sandwich domain of Sec23/240.01036Inherited
Integrin domains0.01036Inherited
post-AAA+ oligomerization domain-like0.01036Inherited
ADC-like0.01036Inherited
Terpenoid cyclases/Protein prenyltransferases0.01036Inherited
Cdc48 domain 2-like0.01036Inherited
Cu,Zn superoxide dismutase-like0.01036Inherited
BEACH domain0.01036Inherited
Calcium ATPase, transduction domain A0.01151Inherited
Di-copper centre-containing domain0.01233Inherited
FAD/NAD-linked reductases, dimerisation (C-terminal) domain0.01233Inherited
Translational machinery components0.01233Inherited
Quinoprotein alcohol dehydrogenase-like0.02368Inherited
Hect, E3 ligase catalytic domain0.02507Inherited
cAMP-binding domain-like0.02643Inherited
YWTD domain0.03107Inherited
Invertebrate chitin-binding proteins0.0349Inherited
Chromo domain-like0.03516Inherited
Tubby C-terminal domain-like0.03637Inherited
S15/NS1 RNA-binding domain0.03637Inherited
Cupredoxins0.03637Inherited
Caspase-like0.03637Inherited
Nucleotide-diphospho-sugar transferases0.05531Inherited
PLC-like phosphodiesterases0.05611Inherited
Second domain of FERM0.08814Inherited
Myosin rod fragments0.1014Inherited
Cysteine-rich domain0.1075Inherited
PDZ domain-like0.118Inherited
HAD-like0.1181Inherited
Homeodomain-like0.1191Inherited
FKBP-like0.1458Inherited
BRCT domain0.1875Inherited
CCCH zinc finger0.2157Inherited
p53-like transcription factors0.2543Inherited
UBC-like0.2628Inherited
SH2 domain0.2734Inherited
Multidrug efflux transporter AcrB transmembrane domain0.2784Inherited
CBS-domain pair0.3208Inherited
Cysteine proteinases0.4276Inherited
Transducin (alpha subunit), insertion domain0.4631Inherited
PLP-dependent transferases0.5106Inherited
HSP20-like chaperones0.5151Inherited
E set domains0.5326Inherited
Clavaminate synthase-like0.6139Inherited
Immunoglobulin0.6326Inherited
Lipocalins0.6608Inherited
ABC transporter transmembrane region0.6698Inherited
RING/U-box0.7775Inherited
EF-hand0.7842Inherited
POZ domain0.8695Inherited
S-adenosyl-L-methionine-dependent methyltransferases0.9355Inherited
(Phosphotyrosine protein) phosphatases II0.9859Inherited
Voltage-gated potassium channels0.9979Inherited
Metallo-dependent phosphatases1Inherited
Saposin1Inherited
Thioredoxin-like1Inherited


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Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Helical domain of Sec23/240Direct
L30e/L7ae ribosomal proteins0Direct
XPF/Rad1/Mus81 nuclease0Direct
LEM domain0Direct
SCF ubiquitin ligase complex WHB domain0Direct
Cullin homology domain0Direct
Zn-finger domain of Sec23/240Direct
Arginine methyltransferase0Direct
Smc hinge domain0Direct
Trunk domain of Sec23/240Direct
Protein prenyltransferases0Direct
Clathrin coat assembly domain0Direct
Group II chaperonin (CCT, TRIC), intermediate domain0Direct
DLC0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
DNA replication initiator (cdc21/cdc54) N-terminal domain0Direct
ValRS/IleRS/LeuRS editing domain0Direct
Ribosomal protein L10Direct
RNA-polymerase beta0Direct
Mammalian PLC0Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0Direct
Myotubularin-like phosphatases0Direct
Cullin repeat0Direct
Proteasome subunits0Direct
Profilin (actin-binding protein)0Direct
Phoshoinositide 3-kinase (PI3K) helical domain0Direct
14-3-3 protein0Direct
Heat shock protein 90, HSP90, N-terminal domain0Direct
Lipovitellin-phosvitin complex, superhelical domain0Direct
PX domain0Direct
Acyl-carrier protein (ACP)0Direct
Phoshoinositide 3-kinase (PI3K), catalytic domain0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
DNA repair protein MutS, domain III0Direct
Cell cycle transcription factor e2f-dp0Direct
Lesion bypass DNA polymerase (Y-family), catalytic domain0Direct
DNA gyrase/MutL, second domain0Direct
5' to 3' exonuclease catalytic domain0Direct
Lesion bypass DNA polymerase (Y-family), little finger domain0Direct
Integrin domains0Direct
Ubiquitin activating enzymes (UBA)0Direct
C-terminal, gelsolin-like domain of Sec23/240Direct
HSP90 C-terminal domain0Direct
Sec7 domain0Direct
Lipovitellin-phosvitin complex; beta-sheet shell regions0Direct
beta-sandwich domain of Sec23/240Direct
Clathrin adaptor core protein0Direct
Hsp90 middle domain0Direct
Ribosomal protein S100Direct
5' to 3' exonuclease, C-terminal subdomain0Direct
DEATH domain, DD0Direct
Inositol polyphosphate 5-phosphatase (IPP5)0Direct
Nucleosome core histones0.00000000000002425Direct
Skp1 dimerisation domain-like0.0000000001215Direct
Nicotinic receptor ligand binding domain-like0.0000000001912Direct
Neurotransmitter-gated ion-channel transmembrane pore0.0000000008748Direct
FYVE, a phosphatidylinositol-3-phosphate binding domain0.0000000456Direct
Actin/HSP700.000002867Direct
Extended AAA-ATPase domain0.000003375Direct
Pleckstrin-homology domain (PH domain)0.000003921Direct
WD40-repeat0.000004442Direct
Armadillo repeat0.00004188Direct
t-snare proteins0.00005216Direct
Group II chaperonin (CCT, TRIC), apical domain0.00005216Direct
PLC-like (P variant)0.0001231Direct
Translational machinery components0.0001661Direct
Group II chaperonin (CCT, TRIC), ATPase domain0.0001661Direct
Phosphotyrosine-binding domain (PTB)0.0001883Direct
G proteins0.0002728Direct
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.000357Direct
Pumilio repeat0.000357Direct
Cyclin0.0006728Direct
Class I aminoacyl-tRNA synthetases (RS), catalytic domain0.0006728Direct
Motor proteins0.0008515Direct
Calponin-homology domain, CH-domain0.0008881Direct
SH3-domain0.0009881Direct
Cold shock DNA-binding domain-like0.001256Inherited
Tubulin, C-terminal domain0.001565Inherited
Sec1/munc18-like (SM) proteins0.001653Inherited
RecA protein-like (ATPase-domain)0.001653Inherited
Clc chloride channel0.001653Inherited
HLH, helix-loop-helix DNA-binding domain0.00252Inherited
Calpain large subunit, middle domain (domain III)0.002873Inherited
Tandem AAA-ATPase domain0.002997Inherited
Histone lysine methyltransferases0.003286Inherited
Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain0.003286Inherited
Spectrin repeat0.003538Inherited
Tubulin, GTPase domain0.00356Inherited
EF-hand modules in multidomain proteins0.005166Inherited
Frizzled cysteine-rich domain0.005166Inherited
BAR domain0.005166Inherited
F1F0 ATP synthase subunit C0.005166Inherited
Canonical RBD0.007476Inherited
BTB/POZ domain0.007776Inherited
Prefoldin0.007903Inherited
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0.008946Inherited
Intermediate filament protein, coiled coil region0.009003Inherited
Elongation factors0.01275Inherited
DBL homology domain (DH-domain)0.01275Inherited
Tetratricopeptide repeat (TPR)0.01367Inherited
Ephrin ectodomain0.01588Inherited
Ubiquitin carboxyl-terminal hydrolase UCH-L0.01588Inherited
DNA polymerase III clamp loader subunits, C-terminal domain0.01588Inherited
BEACH domain0.01588Inherited
Caspase catalytic domain0.01588Inherited
DNA gyrase/MutL, N-terminal domain0.01588Inherited
Anticodon-binding domain0.01588Inherited
Hemocyanin middle domain0.01588Inherited
Cdc48 N-terminal domain-like0.01588Inherited
Cdc48 domain 2-like0.01588Inherited
Cu,Zn superoxide dismutase-like0.01588Inherited
Anticodon-binding domain of Class II aaRS0.01588Inherited
FAD/NAD-linked reductases, N-terminal and central domains0.01682Inherited
LIM domain0.02089Inherited
Hedgehog C-terminal (Hog) autoprocessing domain0.02089Inherited
FAD/NAD-linked reductases, dimerisation (C-terminal) domain0.02121Inherited
I set domains0.02128Inherited
PDZ domain0.02804Inherited
Calcium ATPase, transduction domain A0.03342Inherited
cAMP-binding domain0.03476Inherited
Sm motif of small nuclear ribonucleoproteins, SNRNP0.03476Inherited
Nitrogenase iron protein-like0.04045Inherited
Erythroid transcription factor GATA-10.04645Inherited
Hect, E3 ligase catalytic domain0.04645Inherited
Linker histone H1/H50.05202Inherited
DNA polymerase I0.05202Inherited
DEP domain0.05494Inherited
BCR-homology GTPase activation domain (BH-domain)0.06558Inherited
Growth factor receptor domain0.08735Inherited
PHD domain0.1089Inherited
YWTD domain0.1167Inherited
First domain of FERM0.1167Inherited
Class II glutamine amidotransferases0.1167Inherited
Second domain of FERM0.125Inherited
DnaQ-like 3'-5' exonuclease0.125Inherited
Protein kinases, catalytic subunit0.1278Inherited
Calpain large subunit, catalytic domain (domain II)0.1529Inherited
Fatty acid binding protein-like0.1875Inherited
FKBP immunophilin/proline isomerase0.2235Inherited
Homeodomain0.2281Inherited
Third domain of FERM0.2312Inherited
Protein kinase cysteine-rich domain (cys2, phorbol-binding domain)0.2828Inherited
ABC transporter ATPase domain-like0.2943Inherited
Multidrug efflux transporter AcrB transmembrane domain0.3401Inherited
CCCH zinc finger0.391Inherited
CBS-domain pair0.3939Inherited
RING finger domain, C3HC40.5021Inherited
SH2 domain0.5815Inherited
Transducin (alpha subunit), insertion domain0.6424Inherited
UBC-related0.7269Inherited
ABC transporter transmembrane region0.7338Inherited
Glutathione peroxidase-like0.8828Inherited
Voltage-gated potassium channels1Inherited
Glutathione S-transferase (GST), N-terminal domain1Inherited


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Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Smc hinge domain0Direct
Zn-finger domain of Sec23/240Direct
Ribosomal protein L10-like0Direct
Lipovitellin-phosvitin complex; beta-sheet shell regions0Direct
Restriction endonuclease-like0Direct
P-loop containing nucleoside triphosphate hydrolases0Direct
HSP90 C-terminal domain0Direct
The spindle assembly checkpoint protein mad20Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Profilin (actin-binding protein)0Direct
ValRS/IleRS/LeuRS editing domain0Direct
RBP11-like subunits of RNA polymerase0Direct
DLC0Direct
Subdomain of clathrin and coatomer appendage domain0Direct
PX domain0Direct
Lesion bypass DNA polymerase (Y-family), little finger domain0Direct
14-3-3 protein0Direct
Helical domain of Sec23/240Direct
Clathrin adaptor appendage domain0Direct
Ribosomal protein S100Direct
C-terminal, gelsolin-like domain of Sec23/240Direct
LEM domain0Direct
VPS9 domain0Direct
Cullin homology domain0Direct
ARM repeat0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
5' to 3' exonuclease, C-terminal subdomain0Direct
DNA repair protein MutS, domain III0Direct
Lipovitellin-phosvitin complex, superhelical domain0Direct
Ribosomal protein L10Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0Direct
Sec7 domain0Direct
DNA ligase/mRNA capping enzyme, catalytic domain0Direct
Histone-fold7.012e-16Direct
Nicotinic receptor ligand binding domain-like0.0000000000007233Direct
Nucleic acid-binding proteins0.000000000002332Direct
Neurotransmitter-gated ion-channel transmembrane pore0.00000000001416Direct
"Winged helix" DNA-binding domain0.00000000001712Direct
Skp1 dimerisation domain-like0.00000000007227Direct
PH domain-like0.0000000001765Direct
WD40 repeat-like0.000000003729Direct
FYVE/PHD zinc finger0.0000003778Direct
GroEL apical domain-like0.000003412Direct
Translation proteins SH3-like domain0.000007886Direct
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.000008994Direct
SNARE-like0.00001158Direct
GroEL equatorial domain-like0.00001295Direct
t-snare proteins0.00001295Direct
GroEL-intermediate domain like0.00001295Direct
C2 domain (Calcium/lipid-binding domain, CaLB)0.00001321Direct
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.0000275Direct
Translation proteins0.00002804Direct
SH3-domain0.00003766Direct
Activating enzymes of the ubiquitin-like proteins0.00004889Direct
Calponin-homology domain, CH-domain0.00009641Direct
ENTH/VHS domain0.0001304Direct
Actin-like ATPase domain0.0001442Direct
Cyclin-like0.0002293Direct
HLH, helix-loop-helix DNA-binding domain0.0002401Direct
Tubulin C-terminal domain-like0.0003194Direct
Spectrin repeat0.0003802Direct
Lamin A/C globular tail domain0.0003802Direct
Ribosomal protein S5 domain 2-like0.0005108Direct
Sec1/munc18-like (SM) proteins0.0006785Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase0.0006785Direct
Clc chloride channel0.0006785Direct
Tubulin nucleotide-binding domain-like0.0008544Direct
DNA/RNA polymerases0.0009978Direct
Class II aaRS ABD-related0.001055Inherited
Calpain large subunit, middle domain (domain III)0.001055Inherited
Prefoldin0.001055Inherited
PIN domain-like0.001055Inherited
Nucleotidylyl transferase0.001206Inherited
RNA-binding domain, RBD0.00181Inherited
CAD & PB1 domains0.002486Inherited
F1F0 ATP synthase subunit C0.002486Inherited
Frizzled cysteine-rich domain0.002486Inherited
Ribosomal proteins S24e, L23 and L15e0.002486Inherited
Class II aaRS and biotin synthetases0.002651Inherited
Intermediate filament protein, coiled coil region0.003146Inherited
Sm-like ribonucleoproteins0.003415Inherited
DBL homology domain (DH-domain)0.003415Inherited
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0.003467Inherited
DEATH domain0.003467Inherited
Cullin repeat-like0.003467Inherited
L30e-like0.003467Inherited
Growth factor receptor domain0.004276Inherited
Metal cation-transporting ATPase, ATP-binding domain N0.004568Inherited
Protein kinase-like (PK-like)0.004795Inherited
Ubiquitin-like0.005836Inherited
GTPase activation domain, GAP0.006593Inherited
TPR-like0.006606Inherited
BAR/IMD domain-like0.006618Inherited
Calcium ATPase, transmembrane domain M0.007498Inherited
Hedgehog/intein (Hint) domain0.008477Inherited
SET domain0.008679Inherited
Cdc48 domain 2-like0.008923Inherited
BEACH domain0.008923Inherited
Cu,Zn superoxide dismutase-like0.008923Inherited
ADC-like0.008923Inherited
Integrin domains0.008923Inherited
Terpenoid cyclases/Protein prenyltransferases0.008923Inherited
beta-sandwich domain of Sec23/240.008923Inherited
post-AAA+ oligomerization domain-like0.008923Inherited
Zinc beta-ribbon0.009917Inherited
Calcium ATPase, transduction domain A0.00992Inherited
Di-copper centre-containing domain0.01064Inherited
Translational machinery components0.01064Inherited
FAD/NAD-linked reductases, dimerisation (C-terminal) domain0.01064Inherited
Quinoprotein alcohol dehydrogenase-like0.02067Inherited
Hect, E3 ligase catalytic domain0.02191Inherited
cAMP-binding domain-like0.02312Inherited
YWTD domain0.02729Inherited
Invertebrate chitin-binding proteins0.03074Inherited
Chromo domain-like0.03098Inherited
S15/NS1 RNA-binding domain0.03207Inherited
Tubby C-terminal domain-like0.03207Inherited
Caspase-like0.03207Inherited
Cupredoxins0.03207Inherited
Nucleotide-diphospho-sugar transferases0.04913Inherited
PLC-like phosphodiesterases0.04987Inherited
Second domain of FERM0.07931Inherited
Myosin rod fragments0.09157Inherited
Cysteine-rich domain0.09725Inherited
PDZ domain-like0.107Inherited
HAD-like0.1071Inherited
Homeodomain-like0.1081Inherited
FKBP-like0.1332Inherited
BRCT domain0.1724Inherited
CCCH zinc finger0.1994Inherited
p53-like transcription factors0.2365Inherited
UBC-like0.2447Inherited
SH2 domain0.2549Inherited
Multidrug efflux transporter AcrB transmembrane domain0.2598Inherited
CBS-domain pair0.301Inherited
Cysteine proteinases0.4061Inherited
Transducin (alpha subunit), insertion domain0.4415Inherited
PLP-dependent transferases0.4885Inherited
HSP20-like chaperones0.493Inherited
E set domains0.5104Inherited
Clavaminate synthase-like0.5919Inherited
Immunoglobulin0.6107Inherited
Lipocalins0.6395Inherited
ABC transporter transmembrane region0.6486Inherited
RING/U-box0.7581Inherited
EF-hand0.7649Inherited
POZ domain0.8531Inherited
S-adenosyl-L-methionine-dependent methyltransferases0.9218Inherited
(Phosphotyrosine protein) phosphatases II0.9748Inherited
Voltage-gated potassium channels0.9876Inherited
Metallo-dependent phosphatases0.9989Inherited
Saposin0.9992Inherited
Thioredoxin-like1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
56091,50249
  • 56091 - DNA ligase/mRNA capping enzyme, catalytic domain
  • 50249 - Nucleic acid-binding proteins
  • 0Direct
    56968,48431
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 48431 - Lipovitellin-phosvitin complex, superhelical domain
  • 0Direct
    75632,46785
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    49348,55711
  • 49348 - Clathrin adaptor appendage domain
  • 55711 - Subdomain of clathrin and coatomer appendage domain
  • 0Direct
    50692,54585
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 0Direct
    81811,82754
  • 81811 - Helical domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0Direct
    49562,48371
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 0Direct
    82919,53300
  • 82919 - Zn-finger domain of Sec23/24
  • 53300 - vWA-like
  • 0Direct
    54585,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    50677,52374
  • 50677 - ValRS/IleRS/LeuRS editing domain
  • 52374 - Nucleotidylyl transferase
  • 0Direct
    51695,49562
  • 51695 - PLC-like phosphodiesterases
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0Direct
    48425,50729
  • 48425 - Sec7 domain
  • 50729 - PH domain-like
  • 0Direct
    55874,54211
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0Direct
    57903,51197
  • 57903 - FYVE/PHD zinc finger
  • 51197 - Clavaminate synthase-like
  • 0Direct
    52540,47917
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase
  • 0Direct
    48334,52540
  • 48334 - DNA repair protein MutS, domain III
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    57863,48403
  • 57863 - ArfGap/RecO-like zinc finger
  • 48403 - Ankyrin repeat
  • 0Direct
    48431,56968
  • 48431 - Lipovitellin-phosvitin complex, superhelical domain
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 0Direct
    50729,47473
  • 50729 - PH domain-like
  • 47473 - EF-hand
  • 0Direct
    64356,49447
  • 64356 - SNARE-like
  • 49447 - Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor
  • 0Direct
    56672,100879
  • 56672 - DNA/RNA polymerases
  • 100879 - Lesion bypass DNA polymerase (Y-family), little finger domain
  • 0Direct
    46785,144074
  • 46785 - "Winged helix" DNA-binding domain
  • 144074 - E2F-DP heterodimerization region
  • 0Direct
    47473,51695
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 0Direct
    74788,75632
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 0Direct
    63712,90112
  • 63712 - Nicotinic receptor ligand binding domain-like
  • 90112 - Neurotransmitter-gated ion-channel transmembrane pore
  • 0.00000000001416Direct
    54695,81382
  • 54695 - POZ domain
  • 81382 - Skp1 dimerisation domain-like
  • 0.00000000001784Direct
    48371,48371
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 0.0000000485Direct
    54849,52029
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.00001295Direct
    48592,54849
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 0.00001295Direct
    53067,53067
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 0.00003157Direct
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.00009641Direct
    47954,47954
  • 47954 - Cyclin-like
  • 47954 - Cyclin-like
  • 0.0001304Direct
    46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.000183Direct
    54001,49758
  • 54001 - Cysteine proteinases
  • 49758 - Calpain large subunit, middle domain (domain III)
  • 0.000183Direct
    57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.000273Direct
    52490,55307
  • 52490 - Tubulin nucleotide-binding domain-like
  • 55307 - Tubulin C-terminal domain-like
  • 0.0008544Direct
    48452,48452
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 0.0008837Direct
    52540,50447
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 0.00179Inherited
    48371,56112
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.002486Inherited
    52374,47323
  • 52374 - Nucleotidylyl transferase
  • 47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
  • 0.003413Inherited
    50447,50465
  • 50447 - Translation proteins
  • 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
  • 0.003467Inherited
    81660,56784
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 0.004568Inherited
    52540,48019
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 48019 - post-AAA+ oligomerization domain-like
  • 0.008923Inherited
    55550,50044
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0.008923Inherited
    55681,52954
  • 55681 - Class II aaRS and biotin synthetases
  • 52954 - Class II aaRS ABD-related
  • 0.008923Inherited
    81333,81333
  • 81333 - F1F0 ATP synthase subunit C
  • 81333 - F1F0 ATP synthase subunit C
  • 0.008923Inherited
    49265,48726
  • 49265 - Fibronectin type III
  • 48726 - Immunoglobulin
  • 0.008923Inherited
    51905,55424
  • 51905 - FAD/NAD(P)-binding domain
  • 55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain
  • 0.01064Inherited
    54928,54928
  • 54928 - RNA-binding domain, RBD
  • 54928 - RNA-binding domain, RBD
  • 0.01165Inherited
    48065,50729
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0.01329Inherited
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.02729Inherited
    50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0.02729Inherited
    54534,54534
  • 54534 - FKBP-like
  • 54534 - FKBP-like
  • 0.03207Inherited
    50249,55681
  • 50249 - Nucleic acid-binding proteins
  • 55681 - Class II aaRS and biotin synthetases
  • 0.03207Inherited
    52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.03699Inherited
    47031,50729
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.04987Inherited
    53098,56672
  • 53098 - Ribonuclease H-like
  • 56672 - DNA/RNA polymerases
  • 0.07133Inherited
    57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.07507Inherited
    54236,47031
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 0.1435Inherited
    48726,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.1861Inherited
    90229,90229
  • 90229 - CCCH zinc finger
  • 90229 - CCCH zinc finger
  • 0.1861Inherited
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.2305Inherited
    52540,90123
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 90123 - ABC transporter transmembrane region
  • 0.264Inherited
    47895,52540
  • 47895 - Transducin (alpha subunit), insertion domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.4415Inherited
    90123,52540
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.6486Inherited
    52833,47616
  • 52833 - Thioredoxin-like
  • 47616 - GST C-terminal domain-like
  • 1Inherited
    55550,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 1Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    56968,48431,56968
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 48431 - Lipovitellin-phosvitin complex, superhelical domain
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 0Direct
    54585,52540,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    49562,48371,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    46966,46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0Direct
    74788,75632,46785
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    50692,54585,52540
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    50729,47473,51695
  • 50729 - PH domain-like
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 0Direct
    48592,54849,52029
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.00001295Direct
    57716,57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.0003193Direct
    81660,56784,81665
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 81665 - Calcium ATPase, transmembrane domain M
  • 0.002651Inherited
    52540,50447,50465
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
  • 0.003467Inherited
    57424,57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.01715Inherited
    48726,48726,49265
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.04079Inherited
    54236,47031,50729
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.1016Inherited
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.1337Inherited
    90123,52540,90123
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 90123 - ABC transporter transmembrane region
  • 0.264Inherited
    52540,90123,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.264Inherited


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