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Worm Phenotype (WP): blast cell physiology variant

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Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)

Shortest distance to current term (+ for parents, - for children) WP term [WP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + 2:   Variant [WBPhenotype:0000886] <5>
+ 1:   physiology variant [WBPhenotype:0000519] <7>(494|573) (495|248|68)
0:   blast cell physiology variant [WBPhenotype:0000985] <26>(152|155) (154|66|17)
- 1:   cell division variant [WBPhenotype:0000746] <20>(55|56) (55|24|4)
- 1:   cell homeostasis metabolism variant [WBPhenotype:0000585] <12>(66|61) (66|26|11)
- 1:   muscle cell physiology variant [WBPhenotype:0000990] <7>(18|20) (19|12|4)
- 1:   neuron physiology variant [WBPhenotype:0000991] <7>(4|5) (4|1|0)
- 1:   cell secretion variant [WBPhenotype:0000258] <6>(7|7) (7|0|0)
- 1:   cell cycle variant [WBPhenotype:0000740] <5>(7|10) (8|4|1)
- 1:   calcium mediated signaling variant [WBPhenotype:0002170] <4>(0|0) (0|0|0)
- 1:   germ cell physiology variant [WBPhenotype:0000987] <4>(7|5) (7|0|0)
- 1:   nuclear positioning variant [WBPhenotype:0000511] <4>(12|14) (13|5|1)
- 1:   cell death variant [WBPhenotype:0000729] <3>(58|51) (59|17|5)
- 1:   cell membrane physiology variant [WBPhenotype:0001965] <3>(0|0) (0|0|0)
- 1:   membrane trafficking variant [WBPhenotype:0001833] <3>(4|3) (4|1|0)
- 1:   oocyte physiology variant [WBPhenotype:0001424] <3>(13|14) (15|7|1)
- 1:   endocytic transport variant [WBPhenotype:0001421] <2>(28|26) (29|11|2)
- 1:   epithelial cell physiology variant [WBPhenotype:0000986] <2>(3|3) (3|2|1)
- 1:   vesicle trafficking variant [WBPhenotype:0001752] <2>(1|0) (1|0|0)
- 1:   coelomocyte physiology variant [WBPhenotype:0001423] <1>(7|7) (7|2|0)
- 1:   embryonic cell physiology variant [WBPhenotype:0000763] <1>(13|17) (13|7|0)
- 1:   lysosome homeostasis deficient [WBPhenotype:0001784] <1>(0|0) (0|0|0)
- 1:   lysosome organization biogenesis variant [WBPhenotype:0001430] <1>(3|3) (3|2|2)
- 1:   nuclear division variant [WBPhenotype:0000504] <1>(7|8) (7|4|2)
- 1:   plasma membrane composition variant [WBPhenotype:0002177] <1>(4|1) (4|1|1)
- 1:   cell growth variant [WBPhenotype:0010001](0|0) (0|0|0)
- 1:   gland cell physiology variant [WBPhenotype:0000988](0|0) (0|0|0)
- 1:   marginal cell physiology variant [WBPhenotype:0000989](0|0) (0|0|0)
- 1:   peroxisome physiology variant [WBPhenotype:0001264](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
14-3-3 protein0Direct
ARM repeat0Direct
Cullin homology domain0Direct
Lipovitellin-phosvitin complex; beta-sheet shell regions0Direct
Helical domain of Sec23/240Direct
Sec7 domain0Direct
Subdomain of clathrin and coatomer appendage domain0Direct
Restriction endonuclease-like0Direct
DLC0Direct
ValRS/IleRS/LeuRS editing domain0Direct
Ribosomal protein S100Direct
Zn-finger domain of Sec23/240Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0Direct
VPS9 domain0Direct
HSP90 C-terminal domain0Direct
Ribosomal protein L10Direct
Lipovitellin-phosvitin complex, superhelical domain0Direct
Smc hinge domain0Direct
Ribosomal protein L10-like0Direct
Clathrin adaptor appendage domain0Direct
The spindle assembly checkpoint protein mad20Direct
P-loop containing nucleoside triphosphate hydrolases0Direct
Histone-fold0Direct
PX domain0Direct
RBP11-like subunits of RNA polymerase0Direct
DNA ligase/mRNA capping enzyme, catalytic domain0Direct
Type II DNA topoisomerase0Direct
LEM domain0Direct
Lesion bypass DNA polymerase (Y-family), little finger domain0Direct
Profilin (actin-binding protein)0Direct
C-terminal, gelsolin-like domain of Sec23/240Direct
DNA repair protein MutS, domain III0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
5' to 3' exonuclease, C-terminal subdomain0Direct
Nicotinic receptor ligand binding domain-like0.0000000000004475Direct
Nucleic acid-binding proteins0.000000000001469Direct
"Winged helix" DNA-binding domain0.000000000002588Direct
Neurotransmitter-gated ion-channel transmembrane pore0.000000000009503Direct
Skp1 dimerisation domain-like0.00000000006318Direct
PH domain-like0.00000000009077Direct
WD40 repeat-like0.0000000007934Direct
GroEL apical domain-like0.000003542Direct
FYVE/PHD zinc finger0.000005265Direct
Translation proteins SH3-like domain0.000008057Direct
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.000008237Direct
C2 domain (Calcium/lipid-binding domain, CaLB)0.000011Direct
SNARE-like0.00001164Direct
t-snare proteins0.00001362Direct
GroEL-intermediate domain like0.00001362Direct
GroEL equatorial domain-like0.00001362Direct
Translation proteins0.0000264Direct
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.00002847Direct
SH3-domain0.00003073Direct
Activating enzymes of the ubiquitin-like proteins0.00005229Direct
Calponin-homology domain, CH-domain0.0000904Direct
Actin-like ATPase domain0.0001314Direct
ENTH/VHS domain0.0001333Direct
Cyclin-like0.0002186Direct
HLH, helix-loop-helix DNA-binding domain0.0002197Direct
Tubulin C-terminal domain-like0.0003222Direct
Spectrin repeat0.0003993Direct
Lamin A/C globular tail domain0.0003993Direct
Clc chloride channel0.0007419Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase0.0007419Direct
Sec1/munc18-like (SM) proteins0.0007419Direct
Ribosomal protein S5 domain 2-like0.0007458Direct
Tubulin nucleotide-binding domain-like0.0008701Direct
DNA/RNA polymerases0.001031Inherited
Class II aaRS ABD-related0.001135Inherited
PIN domain-like0.001135Inherited
Calpain large subunit, middle domain (domain III)0.001135Inherited
Prefoldin0.001135Inherited
RNA-binding domain, RBD0.001456Inherited
Nucleotidylyl transferase0.001977Inherited
Class II aaRS and biotin synthetases0.002664Inherited
F1F0 ATP synthase subunit C0.002728Inherited
CAD & PB1 domains0.002728Inherited
Ribosomal proteins S24e, L23 and L15e0.002728Inherited
Frizzled cysteine-rich domain0.002728Inherited
Intermediate filament protein, coiled coil region0.003301Inherited
Sm-like ribonucleoproteins0.003468Inherited
DBL homology domain (DH-domain)0.003468Inherited
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0.003687Inherited
Cullin repeat-like0.003687Inherited
L30e-like0.003687Inherited
DEATH domain0.003687Inherited
Protein kinase-like (PK-like)0.004031Inherited
Growth factor receptor domain0.004225Inherited
Metal cation-transporting ATPase, ATP-binding domain N0.004615Inherited
Ubiquitin-like0.005429Inherited
BAR/IMD domain-like0.006545Inherited
GTPase activation domain, GAP0.006744Inherited
TPR-like0.006918Inherited
Calcium ATPase, transmembrane domain M0.007548Inherited
SET domain0.00837Inherited
Hedgehog/intein (Hint) domain0.008986Inherited
beta-sandwich domain of Sec23/240.009839Inherited
ADC-like0.009839Inherited
Integrin domains0.009839Inherited
Cdc48 domain 2-like0.009839Inherited
BEACH domain0.009839Inherited
Cu,Zn superoxide dismutase-like0.009839Inherited
Terpenoid cyclases/Protein prenyltransferases0.009839Inherited
post-AAA+ oligomerization domain-like0.009839Inherited
Calcium ATPase, transduction domain A0.01007Inherited
FAD/NAD-linked reductases, dimerisation (C-terminal) domain0.01154Inherited
Di-copper centre-containing domain0.01154Inherited
Translational machinery components0.01154Inherited
Quinoprotein alcohol dehydrogenase-like0.02112Inherited
Hect, E3 ligase catalytic domain0.02327Inherited
cAMP-binding domain-like0.02402Inherited
YWTD domain0.02919Inherited
Chromo domain-like0.03153Inherited
Invertebrate chitin-binding proteins0.03215Inherited
Cupredoxins0.03464Inherited
Caspase-like0.03464Inherited
Tubby C-terminal domain-like0.03464Inherited
S15/NS1 RNA-binding domain0.03464Inherited
PLC-like phosphodiesterases0.07771Inherited
Second domain of FERM0.08125Inherited
Myosin rod fragments0.09595Inherited
Cysteine-rich domain0.09614Inherited
Homeodomain-like0.09996Inherited
PDZ domain-like0.101Inherited
HAD-like0.1025Inherited
FKBP-like0.1407Inherited
CCCH zinc finger0.2001Inherited
p53-like transcription factors0.2372Inherited
UBC-like0.243Inherited
Multidrug efflux transporter AcrB transmembrane domain0.259Inherited
SH2 domain0.2905Inherited
CBS-domain pair0.3066Inherited
BRCT domain0.4312Inherited
Transducin (alpha subunit), insertion domain0.4459Inherited
Cysteine proteinases0.4637Inherited
HSP20-like chaperones0.4989Inherited
E set domains0.5794Inherited
Immunoglobulin0.6011Inherited
Lipocalins0.6481Inherited
ABC transporter transmembrane region0.6513Inherited
EF-hand0.7105Inherited
PLP-dependent transferases0.759Inherited
Clavaminate synthase-like0.7835Inherited
RING/U-box0.7895Inherited
S-adenosyl-L-methionine-dependent methyltransferases0.8556Inherited
POZ domain0.8887Inherited
Voltage-gated potassium channels0.9992Inherited
(Phosphotyrosine protein) phosphatases II1Inherited
Metallo-dependent phosphatases1Inherited
Saposin1Inherited
Thioredoxin-like1Inherited


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Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Clathrin coat assembly domain0Direct
Cullin repeat0Direct
Trunk domain of Sec23/240Direct
Profilin (actin-binding protein)0Direct
Acyl-carrier protein (ACP)0Direct
beta-sandwich domain of Sec23/240Direct
Cell cycle transcription factor e2f-dp0Direct
ValRS/IleRS/LeuRS editing domain0Direct
Protein prenyltransferases0Direct
Ribosomal protein L10Direct
Helical domain of Sec23/240Direct
Lipovitellin-phosvitin complex; beta-sheet shell regions0Direct
Lesion bypass DNA polymerase (Y-family), little finger domain0Direct
14-3-3 protein0Direct
Hsp90 middle domain0Direct
Heat shock protein 90, HSP90, N-terminal domain0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Phoshoinositide 3-kinase (PI3K) helical domain0Direct
Sec7 domain0Direct
DNA replication initiator (cdc21/cdc54) N-terminal domain0Direct
PX domain0Direct
5' to 3' exonuclease, C-terminal subdomain0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
DNA repair protein MutS, domain III0Direct
Integrin domains0Direct
Type II DNA topoisomerase0Direct
HSP90 C-terminal domain0Direct
Group II chaperonin (CCT, TRIC), intermediate domain0Direct
Proteasome subunits0Direct
Ribosomal protein S100Direct
5' to 3' exonuclease catalytic domain0Direct
XPF/Rad1/Mus81 nuclease0Direct
Lipovitellin-phosvitin complex, superhelical domain0Direct
Smc hinge domain0Direct
DNA gyrase/MutL, second domain0Direct
Phoshoinositide 3-kinase (PI3K), catalytic domain0Direct
Cullin homology domain0Direct
RNA-polymerase beta0Direct
C-terminal, gelsolin-like domain of Sec23/240Direct
Arginine methyltransferase0Direct
LEM domain0Direct
Lesion bypass DNA polymerase (Y-family), catalytic domain0Direct
Inositol polyphosphate 5-phosphatase (IPP5)0Direct
Myotubularin-like phosphatases0Direct
Mammalian PLC0Direct
Clathrin adaptor core protein0Direct
Ubiquitin activating enzymes (UBA)0Direct
DEATH domain, DD0Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0Direct
DLC0Direct
SCF ubiquitin ligase complex WHB domain0Direct
L30e/L7ae ribosomal proteins0Direct
Zn-finger domain of Sec23/240Direct
Nucleosome core histones0.00000000000001353Direct
Skp1 dimerisation domain-like0.0000000000965Direct
Nicotinic receptor ligand binding domain-like0.0000000001353Direct
Neurotransmitter-gated ion-channel transmembrane pore0.0000000005299Direct
FYVE, a phosphatidylinositol-3-phosphate binding domain0.00000003869Direct
WD40-repeat0.000001307Direct
Actin/HSP700.000002368Direct
Extended AAA-ATPase domain0.000002602Direct
Pleckstrin-homology domain (PH domain)0.000003094Direct
Armadillo repeat0.0000376Direct
t-snare proteins0.00004782Direct
Group II chaperonin (CCT, TRIC), apical domain0.00004782Direct
PLC-like (P variant)0.0001122Direct
Translational machinery components0.0001547Direct
Group II chaperonin (CCT, TRIC), ATPase domain0.0001547Direct
Phosphotyrosine-binding domain (PTB)0.0001702Direct
G proteins0.0002429Direct
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.0003296Direct
Class I aminoacyl-tRNA synthetases (RS), catalytic domain0.0006015Direct
Cyclin0.0006015Direct
Motor proteins0.0007163Direct
Calponin-homology domain, CH-domain0.0007661Direct
SH3-domain0.0007934Direct
Tandem AAA-ATPase domain0.0008456Direct
Cold shock DNA-binding domain-like0.001104Inherited
Pumilio repeat0.001252Inherited
Tubulin, C-terminal domain0.001411Inherited
RecA protein-like (ATPase-domain)0.001569Inherited
Clc chloride channel0.001569Inherited
Sec1/munc18-like (SM) proteins0.001569Inherited
HLH, helix-loop-helix DNA-binding domain0.002155Inherited
Calpain large subunit, middle domain (domain III)0.002711Inherited
Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain0.002974Inherited
Histone lysine methyltransferases0.002974Inherited
Tubulin, GTPase domain0.003248Inherited
Spectrin repeat0.003304Inherited
F1F0 ATP synthase subunit C0.004962Inherited
Frizzled cysteine-rich domain0.004962Inherited
BAR domain0.004962Inherited
EF-hand modules in multidomain proteins0.004962Inherited
BTB/POZ domain0.006485Inherited
Canonical RBD0.006485Inherited
Prefoldin0.007539Inherited
Intermediate filament protein, coiled coil region0.008459Inherited
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0.008464Inherited
Elongation factors0.01172Inherited
DBL homology domain (DH-domain)0.01172Inherited
Tetratricopeptide repeat (TPR)0.01199Inherited
DNA polymerase III clamp loader subunits, C-terminal domain0.01542Inherited
BEACH domain0.01542Inherited
Hemocyanin middle domain0.01542Inherited
Cdc48 N-terminal domain-like0.01542Inherited
Cdc48 domain 2-like0.01542Inherited
Ubiquitin carboxyl-terminal hydrolase UCH-L0.01542Inherited
Anticodon-binding domain0.01542Inherited
Anticodon-binding domain of Class II aaRS0.01542Inherited
Ephrin ectodomain0.01542Inherited
Cu,Zn superoxide dismutase-like0.01542Inherited
Caspase catalytic domain0.01542Inherited
DNA gyrase/MutL, N-terminal domain0.01542Inherited
FAD/NAD-linked reductases, N-terminal and central domains0.01569Inherited
PDZ domain0.01783Inherited
I set domains0.01966Inherited
LIM domain0.01979Inherited
Hedgehog C-terminal (Hog) autoprocessing domain0.01979Inherited
FAD/NAD-linked reductases, dimerisation (C-terminal) domain0.02041Inherited
Calcium ATPase, transduction domain A0.03102Inherited
cAMP-binding domain0.03289Inherited
Sm motif of small nuclear ribonucleoproteins, SNRNP0.03289Inherited
Nitrogenase iron protein-like0.03852Inherited
Erythroid transcription factor GATA-10.04459Inherited
Hect, E3 ligase catalytic domain0.04459Inherited
DNA polymerase I0.05029Inherited
Linker histone H1/H50.05029Inherited
DEP domain0.05352Inherited
BCR-homology GTPase activation domain (BH-domain)0.0631Inherited
Growth factor receptor domain0.08334Inherited
Protein kinases, catalytic subunit0.1093Inherited
Class II glutamine amidotransferases0.1143Inherited
First domain of FERM0.1143Inherited
YWTD domain0.1143Inherited
Second domain of FERM0.1197Inherited
DnaQ-like 3'-5' exonuclease0.1197Inherited
Calpain large subunit, catalytic domain (domain II)0.1473Inherited
Fatty acid binding protein-like0.1822Inherited
Homeodomain0.2157Inherited
PHD domain0.216Inherited
FKBP immunophilin/proline isomerase0.2215Inherited
Third domain of FERM0.226Inherited
Protein kinase cysteine-rich domain (cys2, phorbol-binding domain)0.2728Inherited
ABC transporter ATPase domain-like0.3117Inherited
Multidrug efflux transporter AcrB transmembrane domain0.3267Inherited
CCCH zinc finger0.381Inherited
CBS-domain pair0.3876Inherited
RING finger domain, C3HC40.6209Inherited
SH2 domain0.622Inherited
Transducin (alpha subunit), insertion domain0.6377Inherited
UBC-related0.7229Inherited
ABC transporter transmembrane region0.7278Inherited
Glutathione peroxidase-like0.8916Inherited
Glutathione S-transferase (GST), N-terminal domain1Inherited
Voltage-gated potassium channels1Inherited


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Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Lipovitellin-phosvitin complex, superhelical domain0Direct
DNA repair protein MutS, domain III0Direct
DNA ligase/mRNA capping enzyme, catalytic domain0Direct
Restriction endonuclease-like0Direct
Ribosomal protein L10Direct
RBP11-like subunits of RNA polymerase0Direct
Type II DNA topoisomerase0Direct
Profilin (actin-binding protein)0Direct
Zn-finger domain of Sec23/240Direct
ValRS/IleRS/LeuRS editing domain0Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0Direct
LEM domain0Direct
Lesion bypass DNA polymerase (Y-family), little finger domain0Direct
PX domain0Direct
Helical domain of Sec23/240Direct
Histone-fold0Direct
DLC0Direct
Cullin homology domain0Direct
Subdomain of clathrin and coatomer appendage domain0Direct
Lipovitellin-phosvitin complex; beta-sheet shell regions0Direct
14-3-3 protein0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Smc hinge domain0Direct
Ribosomal protein S100Direct
Clathrin adaptor appendage domain0Direct
Ribosomal protein L10-like0Direct
VPS9 domain0Direct
Sec7 domain0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
5' to 3' exonuclease, C-terminal subdomain0Direct
The spindle assembly checkpoint protein mad20Direct
C-terminal, gelsolin-like domain of Sec23/240Direct
P-loop containing nucleoside triphosphate hydrolases0Direct
ARM repeat0Direct
HSP90 C-terminal domain0Direct
Nicotinic receptor ligand binding domain-like0.0000000000003488Direct
Nucleic acid-binding proteins0.000000000001147Direct
"Winged helix" DNA-binding domain0.000000000002022Direct
Neurotransmitter-gated ion-channel transmembrane pore0.00000000000744Direct
Skp1 dimerisation domain-like0.00000000004957Direct
PH domain-like0.00000000007126Direct
WD40 repeat-like0.0000000006249Direct
GroEL apical domain-like0.000002855Direct
FYVE/PHD zinc finger0.000004246Direct
Translation proteins SH3-like domain0.000006504Direct
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.000006651Direct
C2 domain (Calcium/lipid-binding domain, CaLB)0.000008889Direct
SNARE-like0.000009416Direct
GroEL equatorial domain-like0.00001102Direct
t-snare proteins0.00001102Direct
GroEL-intermediate domain like0.00001102Direct
Translation proteins0.00002141Direct
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.00002309Direct
SH3-domain0.00002493Direct
Activating enzymes of the ubiquitin-like proteins0.00004252Direct
Calponin-homology domain, CH-domain0.00007365Direct
Actin-like ATPase domain0.0001073Direct
ENTH/VHS domain0.0001088Direct
Cyclin-like0.0001786Direct
HLH, helix-loop-helix DNA-binding domain0.0001795Direct
Tubulin C-terminal domain-like0.0002641Direct
Lamin A/C globular tail domain0.0003277Direct
Spectrin repeat0.0003277Direct
Sec1/munc18-like (SM) proteins0.000612Direct
Clc chloride channel0.000612Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase0.000612Direct
Ribosomal protein S5 domain 2-like0.0006153Direct
Tubulin nucleotide-binding domain-like0.0007189Direct
DNA/RNA polymerases0.000853Direct
Class II aaRS ABD-related0.0009394Direct
PIN domain-like0.0009394Direct
Calpain large subunit, middle domain (domain III)0.0009394Direct
Prefoldin0.0009394Direct
RNA-binding domain, RBD0.001209Inherited
Nucleotidylyl transferase0.001647Inherited
Class II aaRS and biotin synthetases0.002231Inherited
CAD & PB1 domains0.002286Inherited
Frizzled cysteine-rich domain0.002286Inherited
Ribosomal proteins S24e, L23 and L15e0.002286Inherited
F1F0 ATP synthase subunit C0.002286Inherited
Intermediate filament protein, coiled coil region0.002775Inherited
DBL homology domain (DH-domain)0.002916Inherited
Sm-like ribonucleoproteins0.002916Inherited
L30e-like0.003102Inherited
DEATH domain0.003102Inherited
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0.003102Inherited
Cullin repeat-like0.003102Inherited
Protein kinase-like (PK-like)0.003395Inherited
Growth factor receptor domain0.003562Inherited
Metal cation-transporting ATPase, ATP-binding domain N0.003893Inherited
Ubiquitin-like0.004588Inherited
BAR/IMD domain-like0.005544Inherited
GTPase activation domain, GAP0.005715Inherited
TPR-like0.005866Inherited
Calcium ATPase, transmembrane domain M0.00641Inherited
SET domain0.007122Inherited
Hedgehog/intein (Hint) domain0.007656Inherited
Cu,Zn superoxide dismutase-like0.008395Inherited
Terpenoid cyclases/Protein prenyltransferases0.008395Inherited
Cdc48 domain 2-like0.008395Inherited
ADC-like0.008395Inherited
Integrin domains0.008395Inherited
post-AAA+ oligomerization domain-like0.008395Inherited
BEACH domain0.008395Inherited
beta-sandwich domain of Sec23/240.008395Inherited
Calcium ATPase, transduction domain A0.008593Inherited
Zinc beta-ribbon0.009079Inherited
Translational machinery components0.009874Inherited
FAD/NAD-linked reductases, dimerisation (C-terminal) domain0.009874Inherited
Di-copper centre-containing domain0.009874Inherited
Quinoprotein alcohol dehydrogenase-like0.01829Inherited
Hect, E3 ligase catalytic domain0.0202Inherited
cAMP-binding domain-like0.02087Inherited
YWTD domain0.02549Inherited
Chromo domain-like0.02756Inherited
Invertebrate chitin-binding proteins0.02812Inherited
Cupredoxins0.03035Inherited
S15/NS1 RNA-binding domain0.03035Inherited
Tubby C-terminal domain-like0.03035Inherited
Caspase-like0.03035Inherited
Nucleotide-diphospho-sugar transferases0.03913Inherited
PLC-like phosphodiesterases0.0694Inherited
Second domain of FERM0.07269Inherited
Myosin rod fragments0.08631Inherited
Cysteine-rich domain0.08648Inherited
Homeodomain-like0.09004Inherited
PDZ domain-like0.09098Inherited
HAD-like0.09239Inherited
FKBP-like0.128Inherited
CCCH zinc finger0.1838Inherited
p53-like transcription factors0.2195Inherited
UBC-like0.225Inherited
Multidrug efflux transporter AcrB transmembrane domain0.2404Inherited
SH2 domain0.271Inherited
CBS-domain pair0.287Inherited
BRCT domain0.4092Inherited
Transducin (alpha subunit), insertion domain0.4239Inherited
Cysteine proteinases0.4418Inherited
HSP20-like chaperones0.4768Inherited
E set domains0.5571Inherited
Immunoglobulin0.5788Inherited
Lipocalins0.626Inherited
ABC transporter transmembrane region0.6293Inherited
EF-hand0.6902Inherited
PLP-dependent transferases0.7399Inherited
Clavaminate synthase-like0.7653Inherited
RING/U-box0.7715Inherited
S-adenosyl-L-methionine-dependent methyltransferases0.8398Inherited
POZ domain0.8739Inherited
Voltage-gated potassium channels0.9898Inherited
(Phosphotyrosine protein) phosphatases II0.9999Inherited
Metallo-dependent phosphatases1Inherited
Thioredoxin-like1Inherited
Saposin1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
51695,49562
  • 51695 - PLC-like phosphodiesterases
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0Direct
    48334,52540
  • 48334 - DNA repair protein MutS, domain III
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    50692,54585
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 0Direct
    48431,56968
  • 48431 - Lipovitellin-phosvitin complex, superhelical domain
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 0Direct
    57863,48403
  • 57863 - ArfGap/RecO-like zinc finger
  • 48403 - Ankyrin repeat
  • 0Direct
    64356,49447
  • 64356 - SNARE-like
  • 49447 - Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor
  • 0Direct
    47473,51695
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 0Direct
    49562,48371
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 0Direct
    56672,100879
  • 56672 - DNA/RNA polymerases
  • 100879 - Lesion bypass DNA polymerase (Y-family), little finger domain
  • 0Direct
    49348,55711
  • 49348 - Clathrin adaptor appendage domain
  • 55711 - Subdomain of clathrin and coatomer appendage domain
  • 0Direct
    55874,54211
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0Direct
    81811,82754
  • 81811 - Helical domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0Direct
    50729,47473
  • 50729 - PH domain-like
  • 47473 - EF-hand
  • 0Direct
    56968,48431
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 48431 - Lipovitellin-phosvitin complex, superhelical domain
  • 0Direct
    56091,50249
  • 56091 - DNA ligase/mRNA capping enzyme, catalytic domain
  • 50249 - Nucleic acid-binding proteins
  • 0Direct
    82919,53300
  • 82919 - Zn-finger domain of Sec23/24
  • 53300 - vWA-like
  • 0Direct
    74788,75632
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 0Direct
    75632,46785
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    50677,52374
  • 50677 - ValRS/IleRS/LeuRS editing domain
  • 52374 - Nucleotidylyl transferase
  • 0Direct
    46785,144074
  • 46785 - "Winged helix" DNA-binding domain
  • 144074 - E2F-DP heterodimerization region
  • 0Direct
    52540,47917
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase
  • 0Direct
    54585,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    48425,50729
  • 48425 - Sec7 domain
  • 50729 - PH domain-like
  • 0Direct
    63712,90112
  • 63712 - Nicotinic receptor ligand binding domain-like
  • 90112 - Neurotransmitter-gated ion-channel transmembrane pore
  • 0.00000000000744Direct
    54695,81382
  • 54695 - POZ domain
  • 81382 - Skp1 dimerisation domain-like
  • 0.00000000001241Direct
    48371,48371
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 0.0000000368Direct
    48592,54849
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 0.00001102Direct
    54849,52029
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.00001102Direct
    53067,53067
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 0.00002332Direct
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.00003723Direct
    47954,47954
  • 47954 - Cyclin-like
  • 47954 - Cyclin-like
  • 0.0001088Direct
    46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.0001623Direct
    54001,49758
  • 54001 - Cysteine proteinases
  • 49758 - Calpain large subunit, middle domain (domain III)
  • 0.0001623Direct
    57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.0002229Direct
    48452,48452
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 0.0007186Direct
    52490,55307
  • 52490 - Tubulin nucleotide-binding domain-like
  • 55307 - Tubulin C-terminal domain-like
  • 0.0007189Direct
    52540,50447
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 0.001518Inherited
    48371,56112
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.002286Inherited
    52374,47323
  • 52374 - Nucleotidylyl transferase
  • 47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
  • 0.003096Inherited
    50447,50465
  • 50447 - Translation proteins
  • 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
  • 0.003102Inherited
    81660,56784
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 0.003893Inherited
    81333,81333
  • 81333 - F1F0 ATP synthase subunit C
  • 81333 - F1F0 ATP synthase subunit C
  • 0.008395Inherited
    55681,52954
  • 55681 - Class II aaRS and biotin synthetases
  • 52954 - Class II aaRS ABD-related
  • 0.008395Inherited
    49265,48726
  • 49265 - Fibronectin type III
  • 48726 - Immunoglobulin
  • 0.008395Inherited
    52540,48019
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 48019 - post-AAA+ oligomerization domain-like
  • 0.008395Inherited
    55550,50044
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0.008395Inherited
    51905,55424
  • 51905 - FAD/NAD(P)-binding domain
  • 55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain
  • 0.009874Inherited
    54928,54928
  • 54928 - RNA-binding domain, RBD
  • 54928 - RNA-binding domain, RBD
  • 0.01003Inherited
    48065,50729
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0.01195Inherited
    52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.01928Inherited
    50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0.02549Inherited
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.02549Inherited
    50249,55681
  • 50249 - Nucleic acid-binding proteins
  • 55681 - Class II aaRS and biotin synthetases
  • 0.03035Inherited
    54534,54534
  • 54534 - FKBP-like
  • 54534 - FKBP-like
  • 0.03035Inherited
    47031,50729
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.04586Inherited
    53098,56672
  • 53098 - Ribonuclease H-like
  • 56672 - DNA/RNA polymerases
  • 0.06796Inherited
    57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.0694Inherited
    54236,47031
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 0.1348Inherited
    90229,90229
  • 90229 - CCCH zinc finger
  • 90229 - CCCH zinc finger
  • 0.1746Inherited
    48726,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.1746Inherited
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.2106Inherited
    52540,90123
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 90123 - ABC transporter transmembrane region
  • 0.2548Inherited
    47895,52540
  • 47895 - Transducin (alpha subunit), insertion domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.4239Inherited
    90123,52540
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.6293Inherited
    52833,47616
  • 52833 - Thioredoxin-like
  • 47616 - GST C-terminal domain-like
  • 1Inherited
    55550,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 1Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    56968,48431,56968
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 48431 - Lipovitellin-phosvitin complex, superhelical domain
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 0Direct
    50692,54585,52540
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    46966,46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0Direct
    49562,48371,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    50729,47473,51695
  • 50729 - PH domain-like
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 0Direct
    54585,52540,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    74788,75632,46785
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    48592,54849,52029
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.00001102Direct
    57716,57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.0002789Direct
    81660,56784,81665
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 81665 - Calcium ATPase, transmembrane domain M
  • 0.002231Inherited
    52540,50447,50465
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
  • 0.003102Inherited
    57424,57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.01563Inherited
    48726,48726,49265
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.03781Inherited
    54236,47031,50729
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.09517Inherited
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.122Inherited
    52540,90123,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.2548Inherited
    90123,52540,90123
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 90123 - ABC transporter transmembrane region
  • 0.2548Inherited


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