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Worm Phenotype (WP): programmed cell death variant

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Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)

Shortest distance to current term (+ for parents, - for children) WP term [WP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   Variant [WBPhenotype:0000886] <5>
+ + + 3:   physiology variant [WBPhenotype:0000519] <7>(494|573) (495|248|68)
+ + 2:   cell physiology variant [WBPhenotype:0000536] <26>(152|155) (154|66|17)
+ + 2:   blast cell physiology variant [WBPhenotype:0000985] <26>(152|155) (154|66|17)
+ 1:   cell death variant [WBPhenotype:0000729] <3>(58|51) (59|17|5)
0:   programmed cell death variant [WBPhenotype:0001172] <4>(56|48) (57|16|5)
- 1:   apoptosis variant [WBPhenotype:0000730] <13>(51|44) (51|13|5)
- 1:   autophagy variant [WBPhenotype:0000736] <2>(1|0) (1|0|0)
- 1:   non apoptotic cell death variant [WBPhenotype:0001173] <2>(12|10) (12|4|1)
- 1:   somatic cell death variant [WBPhenotype:0000965](3|2) (3|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Subdomain of clathrin and coatomer appendage domain0Direct
DLC0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
VPS9 domain0Direct
Clathrin adaptor appendage domain0Direct
PX domain0Direct
RBP11-like subunits of RNA polymerase0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Skp1 dimerisation domain-like0.00000000000005599Direct
FYVE/PHD zinc finger0.000000003114Direct
Cullin homology domain0.00000005034Direct
GroEL apical domain-like0.0000001457Direct
PH domain-like0.000000638Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase0.0000006482Direct
Cullin repeat-like0.0000015Direct
GroEL-intermediate domain like0.0000015Direct
GroEL equatorial domain-like0.0000015Direct
ENTH/VHS domain0.000006879Direct
Histone-fold0.00001795Direct
Sm-like ribonucleoproteins0.00007128Direct
Nucleic acid-binding proteins0.00008717Direct
SH3-domain0.00008717Direct
Integrin domains0.0001019Direct
DNA repair protein MutS, domain III0.0001019Direct
5' to 3' exonuclease, C-terminal subdomain0.0001019Direct
BAR/IMD domain-like0.0003076Direct
Activating enzymes of the ubiquitin-like proteins0.0003349Direct
WD40 repeat-like0.0003695Direct
F1F0 ATP synthase subunit C0.0004483Direct
Cupredoxins0.0004483Direct
Caspase-like0.0004483Direct
Tubby C-terminal domain-like0.0004483Direct
DEATH domain0.0006806Direct
SNARE-like0.0009126Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.001201Inherited
Sec1/munc18-like (SM) proteins0.001201Inherited
Lamin A/C globular tail domain0.002062Inherited
SET domain0.002932Inherited
PIN domain-like0.004536Inherited
Ubiquitin-like0.006025Inherited
Hect, E3 ligase catalytic domain0.007393Inherited
Intermediate filament protein, coiled coil region0.01597Inherited
Chromo domain-like0.1097Inherited
POZ domain0.1499Inherited
Saposin0.1961Inherited
RNA-binding domain, RBD0.2808Inherited
Protein kinase-like (PK-like)0.392Inherited
PLP-dependent transferases0.5192Inherited
"Winged helix" DNA-binding domain0.5616Inherited
Metallo-dependent phosphatases0.5709Inherited
S-adenosyl-L-methionine-dependent methyltransferases0.5753Inherited
ARM repeat0.6385Inherited
HLH, helix-loop-helix DNA-binding domain0.8071Inherited
Metal cation-transporting ATPase, ATP-binding domain N0.889Inherited
Calcium ATPase, transmembrane domain M0.889Inherited
Calcium ATPase, transduction domain A0.9156Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Cullin repeat0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Phoshoinositide 3-kinase (PI3K) helical domain0Direct
PX domain0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Integrin domains0Direct
Group II chaperonin (CCT, TRIC), intermediate domain0Direct
RNA-polymerase beta0Direct
Arginine methyltransferase0Direct
Myotubularin-like phosphatases0Direct
DLC0Direct
SCF ubiquitin ligase complex WHB domain0Direct
FYVE, a phosphatidylinositol-3-phosphate binding domain6.464e-16Direct
Skp1 dimerisation domain-like0.0000000000002427Direct
Group II chaperonin (CCT, TRIC), apical domain0.0000001124Direct
Cullin homology domain0.000000148Direct
Group II chaperonin (CCT, TRIC), ATPase domain0.000001062Direct
RecA protein-like (ATPase-domain)0.000001564Direct
Nucleosome core histones0.00006934Direct
BTB/POZ domain0.0001111Direct
5' to 3' exonuclease, C-terminal subdomain0.0001679Direct
DNA repair protein MutS, domain III0.0001679Direct
5' to 3' exonuclease catalytic domain0.0001679Direct
Ephrin ectodomain0.0001679Direct
Caspase catalytic domain0.0001679Direct
Cold shock DNA-binding domain-like0.0002639Direct
Clathrin adaptor core protein0.0002712Direct
SH3-domain0.0005978Direct
F1F0 ATP synthase subunit C0.0007354Direct
BAR domain0.0007354Direct
Ubiquitin activating enzymes (UBA)0.0007354Direct
Sm motif of small nuclear ribonucleoproteins, SNRNP0.001262Inherited
Phosphotyrosine-binding domain (PTB)0.001262Inherited
Histone lysine methyltransferases0.001512Inherited
Sec1/munc18-like (SM) proteins0.001959Inherited
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.001959Inherited
Armadillo repeat0.006004Inherited
Protein kinases, catalytic subunit0.006025Inherited
Translational machinery components0.007335Inherited
Hect, E3 ligase catalytic domain0.01189Inherited
Proteasome subunits0.01243Inherited
Intermediate filament protein, coiled coil region0.02547Inherited
Canonical RBD0.3858Inherited
ABC transporter ATPase domain-like0.5773Inherited
HLH, helix-loop-helix DNA-binding domain0.7862Inherited
G proteins0.8037Inherited
Calcium ATPase, transduction domain A0.8998Inherited
Phoshoinositide 3-kinase (PI3K), catalytic domain1Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
RBP11-like subunits of RNA polymerase0Direct
PX domain0Direct
DLC0Direct
Subdomain of clathrin and coatomer appendage domain0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Clathrin adaptor appendage domain0Direct
VPS9 domain0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Skp1 dimerisation domain-like0.00000000000004355Direct
FYVE/PHD zinc finger0.000000002461Direct
Cullin homology domain0.00000004Direct
GroEL apical domain-like0.000000116Direct
PH domain-like0.000000511Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase0.0000005192Direct
GroEL equatorial domain-like0.000001205Direct
GroEL-intermediate domain like0.000001205Direct
Cullin repeat-like0.000001205Direct
ENTH/VHS domain0.000005553Direct
Histone-fold0.00001454Direct
Sm-like ribonucleoproteins0.00005798Direct
Nucleic acid-binding proteins0.00007099Direct
SH3-domain0.00007099Direct
DNA repair protein MutS, domain III0.00008308Direct
Integrin domains0.00008308Direct
5' to 3' exonuclease, C-terminal subdomain0.00008308Direct
BAR/IMD domain-like0.000252Direct
Activating enzymes of the ubiquitin-like proteins0.0002746Direct
WD40 repeat-like0.000303Direct
Cupredoxins0.0003684Direct
Tubby C-terminal domain-like0.0003684Direct
F1F0 ATP synthase subunit C0.0003684Direct
Caspase-like0.0003684Direct
DEATH domain0.0005613Direct
SNARE-like0.0007544Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.0009951Direct
Sec1/munc18-like (SM) proteins0.0009951Direct
FAD/NAD-linked reductases, dimerisation (C-terminal) domain0.0009951Direct
Lamin A/C globular tail domain0.00172Inherited
SET domain0.002458Inherited
PIN domain-like0.003826Inherited
Ubiquitin-like0.005098Inherited
Hect, E3 ligase catalytic domain0.006276Inherited
Intermediate filament protein, coiled coil region0.01374Inherited
Chromo domain-like0.09901Inherited
POZ domain0.1367Inherited
Saposin0.1799Inherited
RNA-binding domain, RBD0.2616Inherited
Protein kinase-like (PK-like)0.3708Inherited
PLP-dependent transferases0.4966Inherited
"Winged helix" DNA-binding domain0.5391Inherited
Metallo-dependent phosphatases0.5485Inherited
S-adenosyl-L-methionine-dependent methyltransferases0.5529Inherited
ARM repeat0.6165Inherited
HLH, helix-loop-helix DNA-binding domain0.7893Inherited
Calcium ATPase, transmembrane domain M0.8741Inherited
Metal cation-transporting ATPase, ATP-binding domain N0.8741Inherited
Calcium ATPase, transduction domain A0.9021Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
49562,48371
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 0Direct
    49348,55711
  • 49348 - Clathrin adaptor appendage domain
  • 55711 - Subdomain of clathrin and coatomer appendage domain
  • 0Direct
    74788,75632
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 0Direct
    75632,46785
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    52540,47917
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase
  • 0Direct
    54695,81382
  • 54695 - POZ domain
  • 81382 - Skp1 dimerisation domain-like
  • 0.0000000000001198Direct
    48592,54849
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 0.000001205Direct
    54849,52029
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.000001205Direct
    48334,52540
  • 48334 - DNA repair protein MutS, domain III
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.00008308Direct
    81333,81333
  • 81333 - F1F0 ATP synthase subunit C
  • 81333 - F1F0 ATP synthase subunit C
  • 0.00008308Direct
    51905,55424
  • 51905 - FAD/NAD(P)-binding domain
  • 55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain
  • 0.0009951Direct
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.001816Inherited
    54928,54928
  • 54928 - RNA-binding domain, RBD
  • 54928 - RNA-binding domain, RBD
  • 0.012Inherited
    57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.03249Inherited
    81660,56784
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 0.8741Inherited
    48371,56112
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.9629Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    49562,48371,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    74788,75632,46785
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    48592,54849,52029
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.000001205Direct
    57424,57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.01374Inherited
    81660,56784,81665
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 81665 - Calcium ATPase, transmembrane domain M
  • 0.8741Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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