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Worm Phenotype (WP): programmed cell death variant

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Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)

Shortest distance to current term (+ for parents, - for children) WP term [WP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   Variant [WBPhenotype:0000886] <2>
+ + + 3:   physiology variant [WBPhenotype:0000519] <14>(510|587) (510|248|69)
+ + 2:   cell physiology variant [WBPhenotype:0000536] <36>(149|149) (150|64|19)
+ 1:   cell death variant [WBPhenotype:0000729] <3>(58|51) (58|15|5)
0:   programmed cell death variant [WBPhenotype:0001172] <3>(56|48) (56|14|5)
- 1:   apoptosis variant [WBPhenotype:0000730] <13>(51|44) (51|12|5)
- 1:   non apoptotic cell death variant [WBPhenotype:0001173] <2>(3|3) (3|1|0)
- 1:   somatic cell death variant [WBPhenotype:0000965](3|2) (3|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
RBP11-like subunits of RNA polymerase0Direct
Subdomain of clathrin and coatomer appendage domain0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
DLC0Direct
Clathrin adaptor appendage domain0Direct
VPS9 domain0Direct
PX domain0Direct
Skp1 dimerisation domain-like0.00000000000007224Direct
FYVE/PHD zinc finger0.000000004127Direct
Cullin homology domain0.00000005555Direct
GroEL apical domain-like0.000000163Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase0.0000007007Direct
PH domain-like0.0000008796Direct
Cullin repeat-like0.000001648Direct
GroEL equatorial domain-like0.000001648Direct
GroEL-intermediate domain like0.000001648Direct
ENTH/VHS domain0.00000763Direct
Histone-fold0.0000227Direct
Sm-like ribonucleoproteins0.0000789Direct
Nucleic acid-binding proteins0.0001038Direct
SH3-domain0.0001038Direct
5' to 3' exonuclease, C-terminal subdomain0.0001065Direct
Integrin domains0.0001065Direct
DNA repair protein MutS, domain III0.0001065Direct
BAR/IMD domain-like0.0003429Direct
Activating enzymes of the ubiquitin-like proteins0.0003554Direct
Tubby C-terminal domain-like0.0004691Direct
Cupredoxins0.0004691Direct
F1F0 ATP synthase subunit C0.0004691Direct
Caspase-like0.0004691Direct
WD40 repeat-like0.0004698Direct
DEATH domain0.0007229Direct
SNARE-like0.0009813Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.001259Inherited
Sec1/munc18-like (SM) proteins0.001259Inherited
Lamin A/C globular tail domain0.002181Inherited
SET domain0.00264Inherited
PIN domain-like0.004738Inherited
Hect, E3 ligase catalytic domain0.007714Inherited
Intermediate filament protein, coiled coil region0.01661Inherited
Chromo domain-like0.1137Inherited
Protein kinase-like (PK-like)0.1167Inherited
POZ domain0.1539Inherited
Saposin0.2021Inherited
ARM repeat0.2273Inherited
RNA-binding domain, RBD0.2983Inherited
PLP-dependent transferases0.5478Inherited
"Winged helix" DNA-binding domain0.5532Inherited
Metallo-dependent phosphatases0.5675Inherited
S-adenosyl-L-methionine-dependent methyltransferases0.635Inherited
HLH, helix-loop-helix DNA-binding domain0.8119Inherited
Metal cation-transporting ATPase, ATP-binding domain N0.8691Inherited
Calcium ATPase, transmembrane domain M0.8691Inherited
Calcium ATPase, transduction domain A0.8975Inherited
Cysteine proteinases1Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Integrin domains0Direct
Phoshoinositide 3-kinase (PI3K) helical domain0Direct
Cullin repeat0Direct
SCF ubiquitin ligase complex WHB domain0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
DLC0Direct
RNA-polymerase beta0Direct
PX domain0Direct
Group II chaperonin (CCT, TRIC), intermediate domain0Direct
Myotubularin-like phosphatases0Direct
Arginine methyltransferase0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
FYVE, a phosphatidylinositol-3-phosphate binding domain6.264e-16Direct
Skp1 dimerisation domain-like0.0000000000002658Direct
Group II chaperonin (CCT, TRIC), apical domain0.000000116Direct
Cullin homology domain0.0000001517Direct
Group II chaperonin (CCT, TRIC), ATPase domain0.000001088Direct
RecA protein-like (ATPase-domain)0.000001592Direct
Nucleosome core histones0.00007476Direct
BTB/POZ domain0.000146Direct
Caspase catalytic domain0.0001679Direct
Ephrin ectodomain0.0001679Direct
5' to 3' exonuclease catalytic domain0.0001679Direct
5' to 3' exonuclease, C-terminal subdomain0.0001679Direct
DNA repair protein MutS, domain III0.0001679Direct
Cold shock DNA-binding domain-like0.0002717Direct
Clathrin adaptor core protein0.000273Direct
SH3-domain0.0006298Direct
BAR domain0.0007372Direct
F1F0 ATP synthase subunit C0.0007372Direct
Ubiquitin activating enzymes (UBA)0.0007372Direct
Histone lysine methyltransferases0.001041Inherited
Phosphotyrosine-binding domain (PTB)0.001282Inherited
Sm motif of small nuclear ribonucleoproteins, SNRNP0.001282Inherited
Sec1/munc18-like (SM) proteins0.001965Inherited
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.001965Inherited
Armadillo repeat0.006046Inherited
Translational machinery components0.007343Inherited
Protein kinases, catalytic subunit0.009991Inherited
Hect, E3 ligase catalytic domain0.01193Inherited
Proteasome subunits0.01252Inherited
Intermediate filament protein, coiled coil region0.02563Inherited
Canonical RBD0.3888Inherited
ABC transporter ATPase domain-like0.5613Inherited
G proteins0.7613Inherited
HLH, helix-loop-helix DNA-binding domain0.7907Inherited
Phoshoinositide 3-kinase (PI3K), catalytic domain0.85Inherited
Calcium ATPase, transduction domain A0.8791Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
PX domain0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
VPS9 domain0Direct
Clathrin adaptor appendage domain0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
DLC0Direct
RBP11-like subunits of RNA polymerase0Direct
Subdomain of clathrin and coatomer appendage domain0Direct
Skp1 dimerisation domain-like0.00000000000005668Direct
FYVE/PHD zinc finger0.000000003285Direct
Cullin homology domain0.00000004443Direct
GroEL apical domain-like0.0000001307Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase0.0000005652Direct
PH domain-like0.0000007099Direct
GroEL equatorial domain-like0.000001333Direct
Cullin repeat-like0.000001333Direct
GroEL-intermediate domain like0.000001333Direct
ENTH/VHS domain0.000006203Direct
Histone-fold0.0000185Direct
Sm-like ribonucleoproteins0.00006454Direct
Nucleic acid-binding proteins0.00008501Direct
SH3-domain0.00008501Direct
DNA repair protein MutS, domain III0.00008722Direct
Integrin domains0.00008722Direct
5' to 3' exonuclease, C-terminal subdomain0.00008722Direct
BAR/IMD domain-like0.0002825Direct
Activating enzymes of the ubiquitin-like proteins0.0002929Direct
Caspase-like0.0003878Direct
F1F0 ATP synthase subunit C0.0003878Direct
Cupredoxins0.0003878Direct
Tubby C-terminal domain-like0.0003878Direct
WD40 repeat-like0.0003884Direct
DEATH domain0.0006Direct
SNARE-like0.0008163Direct
Sec1/munc18-like (SM) proteins0.00105Inherited
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.00105Inherited
Lamin A/C globular tail domain0.001832Inherited
SET domain0.002223Inherited
PIN domain-like0.004022Inherited
Hect, E3 ligase catalytic domain0.006594Inherited
Intermediate filament protein, coiled coil region0.01441Inherited
Chromo domain-like0.103Inherited
Protein kinase-like (PK-like)0.1058Inherited
POZ domain0.1405Inherited
Saposin0.1862Inherited
ARM repeat0.2103Inherited
RNA-binding domain, RBD0.2793Inherited
PLP-dependent transferases0.5258Inherited
"Winged helix" DNA-binding domain0.5313Inherited
Metallo-dependent phosphatases0.5456Inherited
S-adenosyl-L-methionine-dependent methyltransferases0.6131Inherited
HLH, helix-loop-helix DNA-binding domain0.7936Inherited
Metal cation-transporting ATPase, ATP-binding domain N0.8528Inherited
Calcium ATPase, transmembrane domain M0.8528Inherited
Calcium ATPase, transduction domain A0.8822Inherited
Cysteine proteinases1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
75632,46785
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    49348,55711
  • 49348 - Clathrin adaptor appendage domain
  • 55711 - Subdomain of clathrin and coatomer appendage domain
  • 0Direct
    52540,47917
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase
  • 0Direct
    49562,48371
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 0Direct
    74788,75632
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 0Direct
    54695,81382
  • 54695 - POZ domain
  • 81382 - Skp1 dimerisation domain-like
  • 0.0000000000001526Direct
    48592,54849
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 0.000001333Direct
    54849,52029
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.000001333Direct
    48334,52540
  • 48334 - DNA repair protein MutS, domain III
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.00008722Direct
    81333,81333
  • 81333 - F1F0 ATP synthase subunit C
  • 81333 - F1F0 ATP synthase subunit C
  • 0.00008722Direct
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.01068Inherited
    54928,54928
  • 54928 - RNA-binding domain, RBD
  • 54928 - RNA-binding domain, RBD
  • 0.01286Inherited
    81660,56784
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 0.8528Inherited
    48371,56112
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.9438Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    49562,48371,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    74788,75632,46785
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    48592,54849,52029
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.000001333Direct
    57424,57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.01441Inherited
    81660,56784,81665
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 81665 - Calcium ATPase, transmembrane domain M
  • 0.8528Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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