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Worm Phenotype (WP): programmed cell death variant

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Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)

Shortest distance to current term (+ for parents, - for children) WP term [WP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   Variant [WBPhenotype:0000886] <2>
+ + + 3:   physiology variant [WBPhenotype:0000519] <14>(510|587) (510|248|68)
+ + 2:   cell physiology variant [WBPhenotype:0000536] <36>(149|149) (150|64|19)
+ 1:   cell death variant [WBPhenotype:0000729] <3>(58|51) (58|15|5)
0:   programmed cell death variant [WBPhenotype:0001172] <3>(56|48) (56|14|5)
- 1:   apoptosis variant [WBPhenotype:0000730] <13>(51|44) (51|12|5)
- 1:   non apoptotic cell death variant [WBPhenotype:0001173] <2>(3|3) (3|1|0)
- 1:   somatic cell death variant [WBPhenotype:0000965](3|2) (3|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
PX domain0Direct
RBP11-like subunits of RNA polymerase0Direct
DLC0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
VPS9 domain0Direct
Subdomain of clathrin and coatomer appendage domain0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Clathrin adaptor appendage domain0Direct
Skp1 dimerisation domain-like0.00000000000007132Direct
FYVE/PHD zinc finger0.000000004054Direct
Cullin homology domain0.00000005514Direct
GroEL apical domain-like0.0000001616Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase0.0000006966Direct
PH domain-like0.0000008618Direct
GroEL-intermediate domain like0.000001636Direct
GroEL equatorial domain-like0.000001636Direct
Cullin repeat-like0.000001636Direct
ENTH/VHS domain0.000007572Direct
Histone-fold0.00002237Direct
Sm-like ribonucleoproteins0.00007829Direct
Nucleic acid-binding proteins0.0001026Direct
SH3-domain0.0001026Direct
DNA repair protein MutS, domain III0.000106Direct
5' to 3' exonuclease, C-terminal subdomain0.000106Direct
Integrin domains0.000106Direct
BAR/IMD domain-like0.0003403Direct
Activating enzymes of the ubiquitin-like proteins0.0003537Direct
WD40 repeat-like0.0004628Direct
F1F0 ATP synthase subunit C0.0004671Direct
Tubby C-terminal domain-like0.0004671Direct
Cupredoxins0.0004671Direct
Caspase-like0.0004671Direct
DEATH domain0.0007194Direct
SNARE-like0.0009757Direct
Sec1/munc18-like (SM) proteins0.001254Inherited
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.001254Inherited
Lamin A/C globular tail domain0.002171Inherited
SET domain0.002621Inherited
PIN domain-like0.00472Inherited
Hect, E3 ligase catalytic domain0.007687Inherited
Intermediate filament protein, coiled coil region0.01654Inherited
Chromo domain-like0.1134Inherited
Protein kinase-like (PK-like)0.1207Inherited
POZ domain0.1529Inherited
Saposin0.2016Inherited
ARM repeat0.2262Inherited
RNA-binding domain, RBD0.3994Inherited
PLP-dependent transferases0.5468Inherited
"Winged helix" DNA-binding domain0.5519Inherited
Metallo-dependent phosphatases0.5662Inherited
S-adenosyl-L-methionine-dependent methyltransferases0.6336Inherited
HLH, helix-loop-helix DNA-binding domain0.8108Inherited
Calcium ATPase, transmembrane domain M0.8682Inherited
Metal cation-transporting ATPase, ATP-binding domain N0.8682Inherited
Calcium ATPase, transduction domain A0.8969Inherited
Cysteine proteinases1Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
PX domain0Direct
Cullin repeat0Direct
DLC0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Myotubularin-like phosphatases0Direct
SCF ubiquitin ligase complex WHB domain0Direct
Group II chaperonin (CCT, TRIC), intermediate domain0Direct
RNA-polymerase beta0Direct
Phoshoinositide 3-kinase (PI3K) helical domain0Direct
Integrin domains0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Arginine methyltransferase0Direct
FYVE, a phosphatidylinositol-3-phosphate binding domain6.263e-16Direct
Skp1 dimerisation domain-like0.000000000000259Direct
Group II chaperonin (CCT, TRIC), apical domain0.0000001145Direct
Cullin homology domain0.0000001499Direct
Group II chaperonin (CCT, TRIC), ATPase domain0.000001076Direct
RecA protein-like (ATPase-domain)0.000001576Direct
Nucleosome core histones0.0000731Direct
BTB/POZ domain0.000143Direct
Ephrin ectodomain0.0001668Direct
DNA repair protein MutS, domain III0.0001668Direct
5' to 3' exonuclease catalytic domain0.0001668Direct
Caspase catalytic domain0.0001668Direct
5' to 3' exonuclease, C-terminal subdomain0.0001668Direct
Cold shock DNA-binding domain-like0.0002681Direct
Clathrin adaptor core protein0.0002708Direct
SH3-domain0.0006187Direct
BAR domain0.0007322Direct
Ubiquitin activating enzymes (UBA)0.0007322Direct
F1F0 ATP synthase subunit C0.0007322Direct
Histone lysine methyltransferases0.001031Inherited
Phosphotyrosine-binding domain (PTB)0.001271Inherited
Sm motif of small nuclear ribonucleoproteins, SNRNP0.001271Inherited
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.001952Inherited
Sec1/munc18-like (SM) proteins0.001952Inherited
Armadillo repeat0.006003Inherited
Translational machinery components0.007299Inherited
Hect, E3 ligase catalytic domain0.01186Inherited
Proteasome subunits0.01245Inherited
Protein kinases, catalytic subunit0.01397Inherited
Intermediate filament protein, coiled coil region0.0255Inherited
Canonical RBD0.4968Inherited
ABC transporter ATPase domain-like0.5595Inherited
G proteins0.7598Inherited
HLH, helix-loop-helix DNA-binding domain0.7898Inherited
Phoshoinositide 3-kinase (PI3K), catalytic domain0.8492Inherited
Calcium ATPase, transduction domain A0.8785Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Clathrin adaptor appendage domain0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
RBP11-like subunits of RNA polymerase0Direct
VPS9 domain0Direct
Subdomain of clathrin and coatomer appendage domain0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
DLC0Direct
PX domain0Direct
Skp1 dimerisation domain-like0.000000000000056Direct
FYVE/PHD zinc finger0.000000003228Direct
Cullin homology domain0.00000004413Direct
GroEL apical domain-like0.0000001297Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase0.0000005621Direct
PH domain-like0.000000696Direct
GroEL equatorial domain-like0.000001324Direct
GroEL-intermediate domain like0.000001324Direct
Cullin repeat-like0.000001324Direct
ENTH/VHS domain0.000006158Direct
Histone-fold0.00001823Direct
Sm-like ribonucleoproteins0.00006407Direct
SH3-domain0.00008405Direct
Nucleic acid-binding proteins0.00008405Direct
Integrin domains0.00008687Direct
DNA repair protein MutS, domain III0.00008687Direct
5' to 3' exonuclease, C-terminal subdomain0.00008687Direct
BAR/IMD domain-like0.0002805Direct
Activating enzymes of the ubiquitin-like proteins0.0002915Direct
WD40 repeat-like0.0003826Direct
F1F0 ATP synthase subunit C0.0003863Direct
Tubby C-terminal domain-like0.0003863Direct
Cupredoxins0.0003863Direct
Caspase-like0.0003863Direct
DEATH domain0.0005972Direct
SNARE-like0.000812Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.001046Inherited
Sec1/munc18-like (SM) proteins0.001046Inherited
Lamin A/C globular tail domain0.001824Inherited
SET domain0.002208Inherited
PIN domain-like0.004007Inherited
Hect, E3 ligase catalytic domain0.00657Inherited
Intermediate filament protein, coiled coil region0.01436Inherited
Chromo domain-like0.1027Inherited
Protein kinase-like (PK-like)0.1096Inherited
POZ domain0.1395Inherited
Saposin0.1857Inherited
ARM repeat0.2093Inherited
RNA-binding domain, RBD0.3789Inherited
PLP-dependent transferases0.5249Inherited
"Winged helix" DNA-binding domain0.5301Inherited
Metallo-dependent phosphatases0.5443Inherited
S-adenosyl-L-methionine-dependent methyltransferases0.6117Inherited
HLH, helix-loop-helix DNA-binding domain0.7927Inherited
Metal cation-transporting ATPase, ATP-binding domain N0.8519Inherited
Calcium ATPase, transmembrane domain M0.8519Inherited
Calcium ATPase, transduction domain A0.8817Inherited
Cysteine proteinases1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
52540,47917
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase
  • 0Direct
    49562,48371
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 0Direct
    74788,75632
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 0Direct
    75632,46785
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    49348,55711
  • 49348 - Clathrin adaptor appendage domain
  • 55711 - Subdomain of clathrin and coatomer appendage domain
  • 0Direct
    54695,81382
  • 54695 - POZ domain
  • 81382 - Skp1 dimerisation domain-like
  • 0.0000000000001503Direct
    48592,54849
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 0.000001324Direct
    54849,52029
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.000001324Direct
    81333,81333
  • 81333 - F1F0 ATP synthase subunit C
  • 81333 - F1F0 ATP synthase subunit C
  • 0.00008687Direct
    48334,52540
  • 48334 - DNA repair protein MutS, domain III
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.00008687Direct
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.01063Inherited
    54928,54928
  • 54928 - RNA-binding domain, RBD
  • 54928 - RNA-binding domain, RBD
  • 0.03474Inherited
    81660,56784
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 0.8519Inherited
    48371,56112
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.9433Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    49562,48371,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    74788,75632,46785
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    48592,54849,52029
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.000001324Direct
    57424,57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.01436Inherited
    81660,56784,81665
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 81665 - Calcium ATPase, transmembrane domain M
  • 0.8519Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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