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Worm Phenotype (WP): programmed cell death variant

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Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)

Shortest distance to current term (+ for parents, - for children) WP term [WP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   Variant [WBPhenotype:0000886] <5>
+ + + 3:   physiology variant [WBPhenotype:0000519] <6>(495|573) (496|248|69)
+ + 2:   cell physiology variant [WBPhenotype:0000536] <27>(145|145) (146|64|18)
+ 1:   cell death variant [WBPhenotype:0000729] <3>(58|51) (59|17|5)
0:   programmed cell death variant [WBPhenotype:0001172] <3>(56|48) (57|16|5)
- 1:   apoptosis variant [WBPhenotype:0000730] <13>(51|44) (51|13|5)
- 1:   non apoptotic cell death variant [WBPhenotype:0001173] <2>(3|3) (3|1|0)
- 1:   somatic cell death variant [WBPhenotype:0000965](3|2) (3|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
PX domain0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Clathrin adaptor appendage domain0Direct
Subdomain of clathrin and coatomer appendage domain0Direct
DLC0Direct
RBP11-like subunits of RNA polymerase0Direct
VPS9 domain0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Skp1 dimerisation domain-like0.0000000000000468Direct
FYVE/PHD zinc finger0.000000002552Direct
Cullin homology domain0.00000004551Direct
GroEL apical domain-like0.0000001308Direct
PH domain-like0.0000005127Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase0.0000005921Direct
GroEL equatorial domain-like0.000001361Direct
Cullin repeat-like0.000001361Direct
GroEL-intermediate domain like0.000001361Direct
ENTH/VHS domain0.000006204Direct
Histone-fold0.00001521Direct
Sm-like ribonucleoproteins0.00006491Direct
Nucleic acid-binding proteins0.00007622Direct
SH3-domain0.00007622Direct
DNA repair protein MutS, domain III0.00009558Direct
5' to 3' exonuclease, C-terminal subdomain0.00009558Direct
Integrin domains0.00009558Direct
BAR/IMD domain-like0.0002794Direct
Activating enzymes of the ubiquitin-like proteins0.0003126Direct
Cupredoxins0.000423Direct
Tubby C-terminal domain-like0.000423Direct
Caspase-like0.000423Direct
F1F0 ATP synthase subunit C0.000423Direct
DEATH domain0.0006378Direct
WD40 repeat-like0.0007706Direct
SNARE-like0.0008503Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.001138Inherited
Sec1/munc18-like (SM) proteins0.001138Inherited
Lamin A/C globular tail domain0.001943Inherited
SET domain0.002707Inherited
PIN domain-like0.004323Inherited
Hect, E3 ligase catalytic domain0.007071Inherited
Intermediate filament protein, coiled coil region0.01535Inherited
Chromo domain-like0.1077Inherited
POZ domain0.1479Inherited
Saposin0.1933Inherited
RNA-binding domain, RBD0.2729Inherited
Protein kinase-like (PK-like)0.3843Inherited
Metallo-dependent phosphatases0.3844Inherited
PLP-dependent transferases0.5358Inherited
"Winged helix" DNA-binding domain0.571Inherited
ARM repeat0.6103Inherited
S-adenosyl-L-methionine-dependent methyltransferases0.6499Inherited
HLH, helix-loop-helix DNA-binding domain0.8307Inherited
Calcium ATPase, transmembrane domain M0.8846Inherited
Metal cation-transporting ATPase, ATP-binding domain N0.8846Inherited
Calcium ATPase, transduction domain A0.9156Inherited
Cysteine proteinases1Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
RNA-polymerase beta0Direct
Myotubularin-like phosphatases0Direct
DLC0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Arginine methyltransferase0Direct
Group II chaperonin (CCT, TRIC), intermediate domain0Direct
Integrin domains0Direct
PX domain0Direct
Phoshoinositide 3-kinase (PI3K) helical domain0Direct
SCF ubiquitin ligase complex WHB domain0Direct
Cullin repeat0Direct
FYVE, a phosphatidylinositol-3-phosphate binding domain6.283e-16Direct
Skp1 dimerisation domain-like0.0000000000001978Direct
Group II chaperonin (CCT, TRIC), apical domain0.0000001001Direct
Cullin homology domain0.0000001331Direct
Group II chaperonin (CCT, TRIC), ATPase domain0.0000009585Direct
RecA protein-like (ATPase-domain)0.000001427Direct
Nucleosome core histones0.000058Direct
BTB/POZ domain0.00009435Direct
Caspase catalytic domain0.0001569Direct
DNA repair protein MutS, domain III0.0001569Direct
5' to 3' exonuclease catalytic domain0.0001569Direct
5' to 3' exonuclease, C-terminal subdomain0.0001569Direct
Ephrin ectodomain0.0001569Direct
Cold shock DNA-binding domain-like0.0002371Direct
Clathrin adaptor core protein0.0002516Direct
SH3-domain0.0005195Direct
F1F0 ATP synthase subunit C0.0006905Direct
Ubiquitin activating enzymes (UBA)0.0006905Direct
BAR domain0.0006905Direct
Sm motif of small nuclear ribonucleoproteins, SNRNP0.001171Inherited
Phosphotyrosine-binding domain (PTB)0.001171Inherited
Histone lysine methyltransferases0.001392Inherited
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.001849Inherited
Sec1/munc18-like (SM) proteins0.001849Inherited
Armadillo repeat0.00566Inherited
Translational machinery components0.006971Inherited
Protein kinases, catalytic subunit0.007407Inherited
Hect, E3 ligase catalytic domain0.01135Inherited
Proteasome subunits0.01178Inherited
Intermediate filament protein, coiled coil region0.02447Inherited
Canonical RBD0.3732Inherited
ABC transporter ATPase domain-like0.5718Inherited
G proteins0.7888Inherited
HLH, helix-loop-helix DNA-binding domain0.8146Inherited
Calcium ATPase, transduction domain A0.903Inherited
Phoshoinositide 3-kinase (PI3K), catalytic domain1Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Clathrin adaptor appendage domain0Direct
PX domain0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Subdomain of clathrin and coatomer appendage domain0Direct
RBP11-like subunits of RNA polymerase0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
VPS9 domain0Direct
DLC0Direct
Skp1 dimerisation domain-like0.0000000000000366Direct
FYVE/PHD zinc finger0.000000002024Direct
Cullin homology domain0.00000003629Direct
GroEL apical domain-like0.0000001046Direct
PH domain-like0.0000004118Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase0.0000004758Direct
GroEL equatorial domain-like0.000001097Direct
Cullin repeat-like0.000001097Direct
GroEL-intermediate domain like0.000001097Direct
ENTH/VHS domain0.000005022Direct
Histone-fold0.00001233Direct
Sm-like ribonucleoproteins0.00005286Direct
SH3-domain0.00006212Direct
Nucleic acid-binding proteins0.00006212Direct
5' to 3' exonuclease, C-terminal subdomain0.00007798Direct
Integrin domains0.00007798Direct
DNA repair protein MutS, domain III0.00007798Direct
BAR/IMD domain-like0.0002291Direct
Activating enzymes of the ubiquitin-like proteins0.0002564Direct
Tubby C-terminal domain-like0.0003479Direct
Caspase-like0.0003479Direct
F1F0 ATP synthase subunit C0.0003479Direct
Cupredoxins0.0003479Direct
DEATH domain0.0005266Direct
WD40 repeat-like0.0006373Direct
SNARE-like0.0007035Direct
Sec1/munc18-like (SM) proteins0.0009436Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.0009436Direct
FAD/NAD-linked reductases, dimerisation (C-terminal) domain0.0009436Direct
Lamin A/C globular tail domain0.001623Inherited
SET domain0.002274Inherited
PIN domain-like0.003651Inherited
Hect, E3 ligase catalytic domain0.006011Inherited
Intermediate filament protein, coiled coil region0.01323Inherited
Chromo domain-like0.09705Inherited
POZ domain0.1347Inherited
Saposin0.1774Inherited
RNA-binding domain, RBD0.2538Inherited
Protein kinase-like (PK-like)0.3627Inherited
Metallo-dependent phosphatases0.3628Inherited
PLP-dependent transferases0.5131Inherited
"Winged helix" DNA-binding domain0.5487Inherited
ARM repeat0.5881Inherited
S-adenosyl-L-methionine-dependent methyltransferases0.6285Inherited
HLH, helix-loop-helix DNA-binding domain0.8142Inherited
Calcium ATPase, transmembrane domain M0.871Inherited
Metal cation-transporting ATPase, ATP-binding domain N0.871Inherited
Calcium ATPase, transduction domain A0.9031Inherited
Cysteine proteinases1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
75632,46785
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    52540,47917
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase
  • 0Direct
    74788,75632
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 0Direct
    49562,48371
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 0Direct
    49348,55711
  • 49348 - Clathrin adaptor appendage domain
  • 55711 - Subdomain of clathrin and coatomer appendage domain
  • 0Direct
    54695,81382
  • 54695 - POZ domain
  • 81382 - Skp1 dimerisation domain-like
  • 0.000000000000101Direct
    54849,52029
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.000001097Direct
    48592,54849
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 0.000001097Direct
    48334,52540
  • 48334 - DNA repair protein MutS, domain III
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.00007798Direct
    81333,81333
  • 81333 - F1F0 ATP synthase subunit C
  • 81333 - F1F0 ATP synthase subunit C
  • 0.00007798Direct
    51905,55424
  • 51905 - FAD/NAD(P)-binding domain
  • 55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain
  • 0.0009436Direct
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.009285Inherited
    54928,54928
  • 54928 - RNA-binding domain, RBD
  • 54928 - RNA-binding domain, RBD
  • 0.0114Inherited
    57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.0315Inherited
    81660,56784
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 0.871Inherited
    48371,56112
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.9644Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    74788,75632,46785
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    49562,48371,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    48592,54849,52029
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.000001097Direct
    57424,57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.01323Inherited
    81660,56784,81665
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 81665 - Calcium ATPase, transmembrane domain M
  • 0.871Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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