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Worm Phenotype (WP): endocytic transport defect

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Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)

Shortest distance to current term (+ for parents, - for children) WP term [WP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + 5:   Variant [WBPhenotype:0000886] <2>
+ + + + 4:   physiology variant [WBPhenotype:0000519] <14>(510|587) (510|248|68)
+ + + 3:   cell physiology variant [WBPhenotype:0000536] <36>(149|149) (150|64|19)
+ + 2:   vesicle trafficking variant [WBPhenotype:0001752] <2>(31|26) (32|10|2)
+ 1:   endocytic transport variant [WBPhenotype:0001421] <2>(31|26) (32|10|2)
0:   endocytic transport defect [WBPhenotype:0001422] <6>(24|23) (25|9|1)
- 1:   coelomocyte endocytosis defective [WBPhenotype:0001426](5|5) (5|2|0)
- 1:   endocytic recycling defective [WBPhenotype:0001860](0|0) (0|0|0)
- 1:   endosome fusion defective [WBPhenotype:0001638](1|1) (1|0|0)
- 1:   receptor mediated endocytosis defective [WBPhenotype:0001425](13|12) (14|7|1)
- 1:   synaptic vesicle endocytosis variant [WBPhenotype:0001514](0|0) (0|0|0)
- 1:   uptake of yolk defective [WBPhenotype:0001762](0|1) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Neurotransmitter-gated ion-channel transmembrane pore0Direct
Sec7 domain0Direct
Nicotinic receptor ligand binding domain-like0Direct
14-3-3 protein0Direct
t-snare proteins0.0000000001075Direct
GroEL apical domain-like0.00000006089Direct
Class II aaRS ABD-related0.0000001692Direct
Sec1/munc18-like (SM) proteins0.0000003318Direct
GroEL equatorial domain-like0.0000006998Direct
GroEL-intermediate domain like0.0000006998Direct
FYVE/PHD zinc finger0.000001072Direct
F1F0 ATP synthase subunit C0.000004692Direct
ValRS/IleRS/LeuRS editing domain0.000004692Direct
Class II aaRS and biotin synthetases0.000007957Direct
Nucleic acid-binding proteins0.0000242Direct
Sm-like ribonucleoproteins0.00003195Direct
DNA ligase/mRNA capping enzyme, catalytic domain0.00006519Direct
Actin-like ATPase domain0.00006606Direct
CAD & PB1 domains0.0002909Direct
Myosin rod fragments0.000407Direct
Translation proteins0.0004663Direct
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.001258Inherited
ENTH/VHS domain0.004238Inherited
PH domain-like1Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Nicotinic receptor ligand binding domain-like0Direct
Sec7 domain0Direct
14-3-3 protein0Direct
Group II chaperonin (CCT, TRIC), intermediate domain0Direct
Neurotransmitter-gated ion-channel transmembrane pore0Direct
FYVE, a phosphatidylinositol-3-phosphate binding domain0.000000000001666Direct
t-snare proteins0.0000000004205Direct
Group II chaperonin (CCT, TRIC), apical domain0.00000004208Direct
Group II chaperonin (CCT, TRIC), ATPase domain0.0000004504Direct
Sec1/munc18-like (SM) proteins0.0000007413Direct
Actin/HSP700.000002352Direct
F1F0 ATP synthase subunit C0.000008737Direct
ValRS/IleRS/LeuRS editing domain0.000008737Direct
Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain0.000009329Direct
Sm motif of small nuclear ribonucleoproteins, SNRNP0.00006089Direct
Anticodon-binding domain of Class II aaRS0.0001017Direct
Pumilio repeat0.0001054Direct
Armadillo repeat0.0003848Direct
Myosin rod fragments0.0007338Direct
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.001334Inherited
Pleckstrin-homology domain (PH domain)0.003863Inherited
Class I aminoacyl-tRNA synthetases (RS), catalytic domain0.004534Inherited
Myotubularin-like phosphatases1Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
14-3-3 protein0Direct
Neurotransmitter-gated ion-channel transmembrane pore0Direct
Sec7 domain0Direct
Nicotinic receptor ligand binding domain-like0Direct
t-snare proteins0.00000000008508Direct
GroEL apical domain-like0.00000004874Direct
Class II aaRS ABD-related0.0000001358Direct
Sec1/munc18-like (SM) proteins0.0000002669Direct
GroEL-intermediate domain like0.0000005646Direct
GroEL equatorial domain-like0.0000005646Direct
FYVE/PHD zinc finger0.0000008666Direct
ValRS/IleRS/LeuRS editing domain0.000003813Direct
F1F0 ATP synthase subunit C0.000003813Direct
Class II aaRS and biotin synthetases0.000006472Direct
Nucleic acid-binding proteins0.00001974Direct
Sm-like ribonucleoproteins0.00002609Direct
DNA ligase/mRNA capping enzyme, catalytic domain0.00005331Direct
Actin-like ATPase domain0.00005403Direct
CAD & PB1 domains0.0002395Direct
Myosin rod fragments0.000336Direct
Translation proteins0.0003856Direct
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.001049Inherited
Zinc beta-ribbon0.002567Inherited
ENTH/VHS domain0.003593Inherited
PH domain-like0.9994Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
63712,90112
  • 63712 - Nicotinic receptor ligand binding domain-like
  • 90112 - Neurotransmitter-gated ion-channel transmembrane pore
  • 0Direct
    48425,50729
  • 48425 - Sec7 domain
  • 50729 - PH domain-like
  • 0Direct
    54849,52029
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.0000005646Direct
    48592,54849
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 0.0000005646Direct
    50677,52374
  • 50677 - ValRS/IleRS/LeuRS editing domain
  • 52374 - Nucleotidylyl transferase
  • 0.000003813Direct
    53067,53067
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 0.0000116Direct
    81333,81333
  • 81333 - F1F0 ATP synthase subunit C
  • 81333 - F1F0 ATP synthase subunit C
  • 0.00005331Direct
    55681,52954
  • 55681 - Class II aaRS and biotin synthetases
  • 52954 - Class II aaRS ABD-related
  • 0.00005331Direct
    48371,48371
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 0.0001048Direct

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    48592,54849,52029
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.0000005646Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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