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Worm Phenotype (WP): endocytic transport defect

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Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)

Shortest distance to current term (+ for parents, - for children) WP term [WP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   Variant [WBPhenotype:0000886] <5>
+ + + 3:   physiology variant [WBPhenotype:0000519] <7>(494|573) (495|248|68)
+ + 2:   blast cell physiology variant [WBPhenotype:0000985] <26>(152|155) (154|66|17)
+ + 2:   cell physiology variant [WBPhenotype:0000536] <26>(152|155) (154|66|17)
+ 1:   endocytic transport variant [WBPhenotype:0001421] <2>(28|26) (29|11|2)
0:   endocytic transport defect [WBPhenotype:0001422] <7>(27|25) (28|11|2)
- 1:   coelomocyte uptake defective [WBPhenotype:0001426] <1>(5|5) (5|2|0)
- 1:   uptake by intestinal cell defective [WBPhenotype:0001763] <1>(3|3) (3|2|1)
- 1:   endocytic recycling defective [WBPhenotype:0001860](0|0) (0|0|0)
- 1:   endosome fusion defective [WBPhenotype:0001638](1|1) (1|0|0)
- 1:   receptor mediated endocytosis defective [WBPhenotype:0001425](12|11) (13|6|1)
- 1:   synaptic vesicle endocytosis variant [WBPhenotype:0001514](0|0) (0|0|0)
- 1:   uptake of yolk defective [WBPhenotype:0001762](0|1) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
14-3-3 protein0Direct
Sec7 domain0Direct
Neurotransmitter-gated ion-channel transmembrane pore0Direct
Nicotinic receptor ligand binding domain-like0Direct
t-snare proteins0.0000000004311Direct
GroEL apical domain-like0.000000203Direct
Class II aaRS ABD-related0.0000004906Direct
Sec1/munc18-like (SM) proteins0.000000835Direct
GroEL-intermediate domain like0.000002003Direct
GroEL equatorial domain-like0.000002003Direct
Nucleic acid-binding proteins0.000007695Direct
FYVE/PHD zinc finger0.000007931Direct
F1F0 ATP synthase subunit C0.00001014Direct
ValRS/IleRS/LeuRS editing domain0.00001014Direct
Class II aaRS and biotin synthetases0.00002768Direct
Actin-like ATPase domain0.00004954Direct
Sm-like ribonucleoproteins0.00009646Direct
DNA ligase/mRNA capping enzyme, catalytic domain0.0001204Direct
CAD & PB1 domains0.0005275Direct
Myosin rod fragments0.0008265Direct
Translation proteins0.001283Inherited
Lipovitellin-phosvitin complex; beta-sheet shell regions0.001405Inherited
Lipovitellin-phosvitin complex, superhelical domain0.001405Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.002481Inherited
ENTH/VHS domain0.008066Inherited
HSP20-like chaperones0.06119Inherited
PH domain-like1Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Nicotinic receptor ligand binding domain-like0Direct
14-3-3 protein0Direct
Sec7 domain0Direct
Neurotransmitter-gated ion-channel transmembrane pore0Direct
Group II chaperonin (CCT, TRIC), intermediate domain0Direct
FYVE, a phosphatidylinositol-3-phosphate binding domain0.00000000001304Direct
t-snare proteins0.000000001789Direct
Group II chaperonin (CCT, TRIC), apical domain0.0000001502Direct
Actin/HSP700.000001308Direct
Group II chaperonin (CCT, TRIC), ATPase domain0.000001366Direct
Sec1/munc18-like (SM) proteins0.000001946Direct
ValRS/IleRS/LeuRS editing domain0.00001958Direct
F1F0 ATP synthase subunit C0.00001958Direct
Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain0.00003447Direct
Sm motif of small nuclear ribonucleoproteins, SNRNP0.0001708Direct
Anticodon-binding domain of Class II aaRS0.0001939Direct
Pumilio repeat0.000512Direct
Armadillo repeat0.0009165Direct
Lipovitellin-phosvitin complex; beta-sheet shell regions0.002246Inherited
Lipovitellin-phosvitin complex, superhelical domain0.002246Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.002757Inherited
Linker histone H1/H50.00467Inherited
Class I aminoacyl-tRNA synthetases (RS), catalytic domain0.009887Inherited
Pleckstrin-homology domain (PH domain)0.01088Inherited
Myotubularin-like phosphatases1Inherited


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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
14-3-3 protein0Direct
Neurotransmitter-gated ion-channel transmembrane pore0Direct
Sec7 domain0Direct
Nicotinic receptor ligand binding domain-like0Direct
t-snare proteins0.0000000003392Direct
GroEL apical domain-like0.000000162Direct
Class II aaRS ABD-related0.0000003924Direct
Sec1/munc18-like (SM) proteins0.0000006695Direct
GroEL equatorial domain-like0.000001611Direct
GroEL-intermediate domain like0.000001611Direct
Nucleic acid-binding proteins0.000006212Direct
FYVE/PHD zinc finger0.000006401Direct
ValRS/IleRS/LeuRS editing domain0.000008187Direct
F1F0 ATP synthase subunit C0.000008187Direct
Class II aaRS and biotin synthetases0.00002246Direct
Actin-like ATPase domain0.00004027Direct
Sm-like ribonucleoproteins0.00007861Direct
DNA ligase/mRNA capping enzyme, catalytic domain0.00009819Direct
CAD & PB1 domains0.000434Direct
Myosin rod fragments0.0006826Direct
Translation proteins0.001064Inherited
Lipovitellin-phosvitin complex, superhelical domain0.001167Inherited
Lipovitellin-phosvitin complex; beta-sheet shell regions0.001167Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.002075Inherited
Zinc beta-ribbon0.004448Inherited
ENTH/VHS domain0.00686Inherited
HSP20-like chaperones0.05431Inherited
PH domain-like1Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
63712,90112
  • 63712 - Nicotinic receptor ligand binding domain-like
  • 90112 - Neurotransmitter-gated ion-channel transmembrane pore
  • 0Direct
    48425,50729
  • 48425 - Sec7 domain
  • 50729 - PH domain-like
  • 0Direct
    48592,54849
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 0.000001611Direct
    54849,52029
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.000001611Direct
    53067,53067
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 0.000007406Direct
    50677,52374
  • 50677 - ValRS/IleRS/LeuRS editing domain
  • 52374 - Nucleotidylyl transferase
  • 0.000008187Direct
    81333,81333
  • 81333 - F1F0 ATP synthase subunit C
  • 81333 - F1F0 ATP synthase subunit C
  • 0.00009819Direct
    55681,52954
  • 55681 - Class II aaRS and biotin synthetases
  • 52954 - Class II aaRS ABD-related
  • 0.00009819Direct
    48371,48371
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 0.0002731Direct
    48431,56968
  • 48431 - Lipovitellin-phosvitin complex, superhelical domain
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 0.001167Inherited
    56968,48431
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 48431 - Lipovitellin-phosvitin complex, superhelical domain
  • 0.001167Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    48592,54849,52029
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.000001611Direct
    56968,48431,56968
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 48431 - Lipovitellin-phosvitin complex, superhelical domain
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 0.001167Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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