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Worm Phenotype (WP): protein metabolism variant

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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)

Shortest distance to current term (+ for parents, - for children) WP term [WP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   Variant [WBPhenotype:0000886] <5>
+ + + + 4:   organism physiology variant [WBPhenotype:0000576] <10>(354|423) (357|200|60)
+ + + 3:   organism homeostasis metabolism variant [WBPhenotype:0000577] <17>(343|412) (348|198|59)
+ + + 3:   physiology variant [WBPhenotype:0000519] <7>(494|573) (495|248|68)
+ + 2:   cell physiology variant [WBPhenotype:0000536] <26>(152|155) (154|66|17)
+ + 2:   blast cell physiology variant [WBPhenotype:0000985] <26>(152|155) (154|66|17)
+ + 2:   organism metabolism processing variant [WBPhenotype:0000027] <25>(167|178) (172|81|24)
+ 1:   metabolic pathway variant [WBPhenotype:0000463] <8>(34|27) (34|16|8)
+ 1:   cell homeostasis metabolism variant [WBPhenotype:0000585] <12>(66|61) (66|26|11)
0:   protein metabolism variant [WBPhenotype:0001644] <10>(28|24) (28|15|8)
- 1:   translation variant [WBPhenotype:0000121] <4>(0|0) (0|0|0)
- 1:   protein phosphorylation variant [WBPhenotype:0001349] <2>(4|4) (4|3|0)
- 1:   protein methylation variant [WBPhenotype:0001383] <1>(3|2) (3|0|0)
- 1:   proteasome core activity variant [WBPhenotype:0002009](1|1) (1|1|0)
- 1:   protein degradation variant [WBPhenotype:0001645](7|8) (7|4|4)
- 1:   protein stabilization variant [WBPhenotype:0001806](0|0) (0|0|0)
- 1:   protein transport variant [WBPhenotype:0001864](2|1) (2|1|0)
- 1:   protein turnover variant [WBPhenotype:0002010](0|0) (0|0|0)
- 1:   unfolded protein accumulation [WBPhenotype:0001486](0|0) (0|0|0)
- 1:   unfolded protein response variant [WBPhenotype:0001719](6|5) (6|4|2)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
SET domain0.00000001268Direct
Calpain large subunit, middle domain (domain III)0.0000008684Direct
GroEL-intermediate domain like0.000002451Direct
GroEL equatorial domain-like0.000002451Direct
GroEL apical domain-like0.00000579Direct
ADC-like0.00001503Direct
Integrin domains0.00001503Direct
Cdc48 domain 2-like0.00001503Direct
F1F0 ATP synthase subunit C0.00006946Direct
PH domain-like0.0001703Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.0001931Direct
Spectrin repeat0.0002303Direct
Voltage-gated potassium channels0.0006154Direct
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.0006318Direct
cAMP-binding domain-like0.0008335Direct
SNARE-like0.0008335Direct
Protein kinase-like (PK-like)0.00136Inherited
Quinoprotein alcohol dehydrogenase-like0.003635Inherited
Immunoglobulin0.01886Inherited
Lipovitellin-phosvitin complex; beta-sheet shell regions0.02794Inherited
Lipovitellin-phosvitin complex, superhelical domain0.02794Inherited
FYVE/PHD zinc finger0.04351Inherited
Clavaminate synthase-like0.05347Inherited
Sm-like ribonucleoproteins0.06152Inherited
Transducin (alpha subunit), insertion domain0.06152Inherited
Translation proteins0.06446Inherited
Homeodomain-like0.07364Inherited
Cyclin-like0.8893Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Integrin domains0Direct
Histone lysine methyltransferases0.0000005378Direct
Calpain large subunit, middle domain (domain III)0.000002339Direct
Proteasome subunits0.00001229Direct
Cdc48 N-terminal domain-like0.00002685Direct
Cdc48 domain 2-like0.00002685Direct
Group II chaperonin (CCT, TRIC), intermediate domain0.00002685Direct
Group II chaperonin (CCT, TRIC), ATPase domain0.00007255Direct
F1F0 ATP synthase subunit C0.0001233Direct
Group II chaperonin (CCT, TRIC), apical domain0.0001525Direct
Calpain large subunit, catalytic domain (domain II)0.0001687Direct
Spectrin repeat0.0002842Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.0003409Direct
Clathrin adaptor core protein0.0007357Direct
Protein kinases, catalytic subunit0.001569Inherited
LIM domain0.003573Inherited
Voltage-gated potassium channels0.00452Inherited
Pleckstrin-homology domain (PH domain)0.008242Inherited
Lipovitellin-phosvitin complex; beta-sheet shell regions0.02749Inherited
Lipovitellin-phosvitin complex, superhelical domain0.02749Inherited
I set domains0.04989Inherited
Elongation factors0.04989Inherited
Transducin (alpha subunit), insertion domain0.05984Inherited
PHD domain0.09503Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
SET domain0.00000001004Direct
Calpain large subunit, middle domain (domain III)0.0000006964Direct
GroEL equatorial domain-like0.000001974Direct
GroEL-intermediate domain like0.000001974Direct
GroEL apical domain-like0.000004668Direct
Cdc48 domain 2-like0.00001217Direct
ADC-like0.00001217Direct
Integrin domains0.00001217Direct
F1F0 ATP synthase subunit C0.00005648Direct
PH domain-like0.0001389Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.0001578Direct
Spectrin repeat0.0001884Direct
Voltage-gated potassium channels0.0005063Direct
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.0005203Direct
cAMP-binding domain-like0.0006886Direct
SNARE-like0.0006886Direct
Protein kinase-like (PK-like)0.001128Inherited
Quinoprotein alcohol dehydrogenase-like0.003059Inherited
Immunoglobulin0.01628Inherited
Lipovitellin-phosvitin complex, superhelical domain0.02438Inherited
Lipovitellin-phosvitin complex; beta-sheet shell regions0.02438Inherited
FYVE/PHD zinc finger0.03826Inherited
Clavaminate synthase-like0.04729Inherited
Sm-like ribonucleoproteins0.05462Inherited
Transducin (alpha subunit), insertion domain0.05462Inherited
Translation proteins0.05732Inherited
Homeodomain-like0.06569Inherited
Cyclin-like0.8745Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
50692,54585
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 0Direct
    54585,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    54001,49758
  • 54001 - Cysteine proteinases
  • 49758 - Calpain large subunit, middle domain (domain III)
  • 0.0000001844Direct
    48592,54849
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 0.000001974Direct
    54849,52029
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.000001974Direct
    81333,81333
  • 81333 - F1F0 ATP synthase subunit C
  • 81333 - F1F0 ATP synthase subunit C
  • 0.00001217Direct
    46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.0003433Direct
    48065,50729
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0.0004675Direct
    48431,56968
  • 48431 - Lipovitellin-phosvitin complex, superhelical domain
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 0.02438Inherited
    48726,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.02438Inherited
    56968,48431
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 48431 - Lipovitellin-phosvitin complex, superhelical domain
  • 0.02438Inherited
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.04345Inherited
    52540,50447
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 0.04345Inherited
    47895,52540
  • 47895 - Transducin (alpha subunit), insertion domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.05462Inherited
    47954,47954
  • 47954 - Cyclin-like
  • 47954 - Cyclin-like
  • 0.5778Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    50692,54585,52540
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    54585,52540,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    48592,54849,52029
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.000001974Direct
    46966,46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.0001578Direct
    57716,57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.001092Inherited
    56968,48431,56968
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 48431 - Lipovitellin-phosvitin complex, superhelical domain
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 0.02438Inherited
    48726,48726,49265
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.05462Inherited
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.08512Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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