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Worm Phenotype (WP): protein metabolism variant

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Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)

Shortest distance to current term (+ for parents, - for children) WP term [WP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   organism physiology variant [WBPhenotype:0000576] <11>(366|425) (369|192|56)
+ + + + 4:   Variant [WBPhenotype:0000886] <2>
+ + + 3:   organism homeostasis metabolism variant [WBPhenotype:0000577] <16>(358|416) (360|189|55)
+ + + 3:   physiology variant [WBPhenotype:0000519] <15>(509|582) (509|247|68)
+ + 2:   organism metabolism processing variant [WBPhenotype:0000027] <25>(176|187) (179|86|26)
+ + 2:   cell physiology variant [WBPhenotype:0000536] <35>(156|154) (158|67|19)
+ 1:   metabolic pathway variant [WBPhenotype:0000463] <8>(39|31) (40|17|9)
+ 1:   cell homeostasis metabolism variant [WBPhenotype:0000585] <12>(72|65) (73|28|12)
0:   protein metabolism variant [WBPhenotype:0001644] <9>(30|26) (31|15|8)
- 1:   protein modification variant [WBPhenotype:0001382] <9>(13|10) (13|3|0)
- 1:   translation variant [WBPhenotype:0000121] <4>(0|0) (0|0|0)
- 1:   proteasome core activity variant [WBPhenotype:0002009](1|1) (1|1|0)
- 1:   protein degradation variant [WBPhenotype:0001645](7|8) (7|4|4)
- 1:   protein stabilization variant [WBPhenotype:0001806](0|0) (0|0|0)
- 1:   protein transport variant [WBPhenotype:0001864](2|1) (2|1|0)
- 1:   protein turnover variant [WBPhenotype:0002010](0|0) (0|0|0)
- 1:   unfolded protein accumulation [WBPhenotype:0001486](0|0) (0|0|0)
- 1:   unfolded protein response variant [WBPhenotype:0001719](6|5) (6|4|2)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Heme-dependent catalase-like0Direct
Arginase/deacetylase0.000000000009249Direct
SET domain0.00000003044Direct
Calpain large subunit, middle domain (domain III)0.000001593Direct
GroEL equatorial domain-like0.000004469Direct
GroEL-intermediate domain like0.000004469Direct
GroEL apical domain-like0.00001048Direct
Integrin domains0.00002239Direct
ADC-like0.00002239Direct
Cdc48 domain 2-like0.00002239Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.0002834Direct
Spectrin repeat0.0003698Direct
SH3-domain0.0006014Direct
PH domain-like0.0008236Direct
Voltage-gated potassium channels0.001625Inherited
Protein kinase-like (PK-like)0.002633Inherited
Quinoprotein alcohol dehydrogenase-like0.005605Inherited
Lipovitellin-phosvitin complex; beta-sheet shell regions0.006764Inherited
DHS-like NAD/FAD-binding domain0.006764Inherited
Lipovitellin-phosvitin complex, superhelical domain0.006764Inherited
Immunoglobulin0.0244Inherited
Translation proteins0.03554Inherited
Chromo domain-like0.04106Inherited
F1F0 ATP synthase subunit C0.04106Inherited
Sm-like ribonucleoproteins0.04106Inherited
Transducin (alpha subunit), insertion domain0.04919Inherited
Clavaminate synthase-like0.07208Inherited
FYVE/PHD zinc finger0.1168Inherited
Homeodomain-like0.1277Inherited
Cyclin-like0.7849Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Sir2 family of transcriptional regulators0Direct
Histone deacetylase, HDAC0Direct
Integrin domains0Direct
Heme-dependent catalases0Direct
Histone lysine methyltransferases0.0000006652Direct
Calpain large subunit, middle domain (domain III)0.00000414Direct
Cdc48 N-terminal domain-like0.00003907Direct
Cdc48 domain 2-like0.00003907Direct
Group II chaperonin (CCT, TRIC), intermediate domain0.00003907Direct
Group II chaperonin (CCT, TRIC), ATPase domain0.0001149Direct
Group II chaperonin (CCT, TRIC), apical domain0.0002392Direct
Calpain large subunit, catalytic domain (domain II)0.0002863Direct
Spectrin repeat0.000443Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.0004885Direct
G proteins0.002889Inherited
Protein kinases, catalytic subunit0.003444Inherited
LIM domain0.005022Inherited
Lipovitellin-phosvitin complex; beta-sheet shell regions0.007318Inherited
Lipovitellin-phosvitin complex, superhelical domain0.007318Inherited
Voltage-gated potassium channels0.009721Inherited
Pleckstrin-homology domain (PH domain)0.01718Inherited
Elongation factors0.03106Inherited
F1F0 ATP synthase subunit C0.04215Inherited
I set domains0.07698Inherited
Transducin (alpha subunit), insertion domain0.07908Inherited
PHD domain0.1417Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Heme-dependent catalase-like0Direct
Arginase/deacetylase0.000000000007328Direct
SET domain0.00000002442Direct
Calpain large subunit, middle domain (domain III)0.000001294Direct
GroEL equatorial domain-like0.000003642Direct
GroEL-intermediate domain like0.000003642Direct
GroEL apical domain-like0.000008549Direct
Cdc48 domain 2-like0.00001832Direct
ADC-like0.00001832Direct
Integrin domains0.00001832Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.0002342Direct
Spectrin repeat0.0003061Direct
SH3-domain0.0004995Direct
PH domain-like0.0006865Direct
Fibronectin type III0.0009031Direct
Voltage-gated potassium channels0.001362Inherited
Protein kinase-like (PK-like)0.002222Inherited
Quinoprotein alcohol dehydrogenase-like0.004775Inherited
Lipovitellin-phosvitin complex; beta-sheet shell regions0.005782Inherited
DHS-like NAD/FAD-binding domain0.005782Inherited
Lipovitellin-phosvitin complex, superhelical domain0.005782Inherited
Immunoglobulin0.02134Inherited
Translation proteins0.03133Inherited
Chromo domain-like0.03629Inherited
F1F0 ATP synthase subunit C0.03629Inherited
Sm-like ribonucleoproteins0.03629Inherited
Transducin (alpha subunit), insertion domain0.04366Inherited
Clavaminate synthase-like0.06454Inherited
FYVE/PHD zinc finger0.106Inherited
Homeodomain-like0.116Inherited
Cyclin-like0.7659Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
50692,54585
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 0Direct
    54585,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    54001,49758
  • 54001 - Cysteine proteinases
  • 49758 - Calpain large subunit, middle domain (domain III)
  • 0.0000003449Direct
    48592,54849
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 0.000003642Direct
    54849,52029
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.000003642Direct
    46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.0005092Direct
    48065,50729
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0.0007543Direct
    56968,48431
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 48431 - Lipovitellin-phosvitin complex, superhelical domain
  • 0.005782Inherited
    48431,56968
  • 48431 - Lipovitellin-phosvitin complex, superhelical domain
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 0.005782Inherited
    48726,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.01453Inherited
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.02482Inherited
    52540,50447
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 0.02482Inherited
    81333,81333
  • 81333 - F1F0 ATP synthase subunit C
  • 81333 - F1F0 ATP synthase subunit C
  • 0.03629Inherited
    47895,52540
  • 47895 - Transducin (alpha subunit), insertion domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.04366Inherited
    47954,47954
  • 47954 - Cyclin-like
  • 47954 - Cyclin-like
  • 0.5773Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    50692,54585,52540
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    54585,52540,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    48592,54849,52029
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.000003642Direct
    46966,46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.0002342Direct
    57716,57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.001602Inherited
    56968,48431,56968
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 48431 - Lipovitellin-phosvitin complex, superhelical domain
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 0.005782Inherited
    48726,48726,49265
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.03629Inherited
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.05396Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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