SUPERFAMILY 1.75 HMM library and genome assignments server

Superfamily is undergoing a server migration - you are now browsing on the new server. Please contact us if you experience any problems.

Worm Phenotype (WP): protein metabolism variant

(show info)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)

Shortest distance to current term (+ for parents, - for children) WP term [WP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   Variant [WBPhenotype:0000886] <2>
+ + + + 4:   organism physiology variant [WBPhenotype:0000576] <9>(369|431) (372|193|56)
+ + + 3:   physiology variant [WBPhenotype:0000519] <14>(510|587) (510|248|68)
+ + + 3:   organism homeostasis metabolism variant [WBPhenotype:0000577] <16>(361|421) (363|190|55)
+ + 2:   cell physiology variant [WBPhenotype:0000536] <36>(149|149) (150|64|19)
+ + 2:   organism metabolism processing variant [WBPhenotype:0000027] <25>(178|190) (182|87|26)
+ 1:   metabolic pathway variant [WBPhenotype:0000463] <8>(39|32) (39|15|9)
+ 1:   cell homeostasis metabolism variant [WBPhenotype:0000585] <12>(60|54) (60|23|12)
0:   protein metabolism variant [WBPhenotype:0001644] <9>(30|26) (30|15|8)
- 1:   protein modification variant [WBPhenotype:0001382] <9>(13|10) (13|3|0)
- 1:   translation variant [WBPhenotype:0000121] <4>(0|0) (0|0|0)
- 1:   proteasome core activity variant [WBPhenotype:0002009] <1>(1|1) (1|1|0)
- 1:   protein degradation variant [WBPhenotype:0001645](7|8) (7|4|4)
- 1:   protein stabilization variant [WBPhenotype:0001806](0|0) (0|0|0)
- 1:   protein transport variant [WBPhenotype:0001864](2|1) (2|1|0)
- 1:   protein turnover variant [WBPhenotype:0002010](0|0) (0|0|0)
- 1:   unfolded protein accumulation [WBPhenotype:0001486](0|0) (0|0|0)
- 1:   unfolded protein response variant [WBPhenotype:0001719](6|5) (6|4|2)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Heme-dependent catalase-like0Direct
Arginase/deacetylase0.000000000009886Direct
SET domain0.00000003313Direct
Calpain large subunit, middle domain (domain III)0.000001666Direct
GroEL equatorial domain-like0.000004675Direct
GroEL-intermediate domain like0.000004675Direct
GroEL apical domain-like0.00001095Direct
Integrin domains0.00002315Direct
Cdc48 domain 2-like0.00002315Direct
ADC-like0.00002315Direct
F1F0 ATP synthase subunit C0.0001059Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.0002922Direct
Spectrin repeat0.0003833Direct
SH3-domain0.0006372Direct
PH domain-like0.0007933Direct
Voltage-gated potassium channels0.001726Inherited
Quinoprotein alcohol dehydrogenase-like0.005768Inherited
Protein kinase-like (PK-like)0.01226Inherited
Lipovitellin-phosvitin complex, superhelical domain0.01518Inherited
DHS-like NAD/FAD-binding domain0.01518Inherited
Lipovitellin-phosvitin complex; beta-sheet shell regions0.01518Inherited
Immunoglobulin0.02532Inherited
Translation proteins0.03052Inherited
FYVE/PHD zinc finger0.05466Inherited
Sm-like ribonucleoproteins0.06951Inherited
Transducin (alpha subunit), insertion domain0.06951Inherited
Chromo domain-like0.06951Inherited
Clavaminate synthase-like0.07361Inherited
Homeodomain-like0.1319Inherited
Cyclin-like0.9083Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Sir2 family of transcriptional regulators0Direct
Histone deacetylase, HDAC0Direct
Heme-dependent catalases0Direct
Integrin domains0Direct
Histone lysine methyltransferases0.0000006947Direct
Calpain large subunit, middle domain (domain III)0.00000427Direct
Cdc48 N-terminal domain-like0.00003991Direct
Group II chaperonin (CCT, TRIC), intermediate domain0.00003991Direct
Cdc48 domain 2-like0.00003991Direct
Group II chaperonin (CCT, TRIC), ATPase domain0.0001177Direct
F1F0 ATP synthase subunit C0.0001814Direct
Group II chaperonin (CCT, TRIC), apical domain0.0002449Direct
Calpain large subunit, catalytic domain (domain II)0.0002941Direct
Spectrin repeat0.0004538Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.0004986Direct
G proteins0.0006917Direct
LIM domain0.005107Inherited
Voltage-gated potassium channels0.01009Inherited
Protein kinases, catalytic subunit0.01257Inherited
Elongation factors0.01569Inherited
Lipovitellin-phosvitin complex, superhelical domain0.01569Inherited
Lipovitellin-phosvitin complex; beta-sheet shell regions0.01569Inherited
Pleckstrin-homology domain (PH domain)0.02738Inherited
Transducin (alpha subunit), insertion domain0.07986Inherited
PHD domain0.1116Inherited
I set domains0.1393Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
Plot tree as:   Download Newick format tree:
(show help)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Heme-dependent catalase-like0Direct
Arginase/deacetylase0.000000000007803Direct
SET domain0.00000002648Direct
Calpain large subunit, middle domain (domain III)0.000001349Direct
GroEL-intermediate domain like0.000003799Direct
GroEL equatorial domain-like0.000003799Direct
GroEL apical domain-like0.000008907Direct
Integrin domains0.00001888Direct
Cdc48 domain 2-like0.00001888Direct
ADC-like0.00001888Direct
F1F0 ATP synthase subunit C0.00008676Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.0002406Direct
Spectrin repeat0.0003161Direct
SH3-domain0.000528Direct
PH domain-like0.0006596Direct
Voltage-gated potassium channels0.001444Inherited
Quinoprotein alcohol dehydrogenase-like0.00491Inherited
Protein kinase-like (PK-like)0.01058Inherited
Lipovitellin-phosvitin complex; beta-sheet shell regions0.01315Inherited
Lipovitellin-phosvitin complex, superhelical domain0.01315Inherited
DHS-like NAD/FAD-binding domain0.01315Inherited
Immunoglobulin0.02215Inherited
Translation proteins0.02681Inherited
FYVE/PHD zinc finger0.04854Inherited
Sm-like ribonucleoproteins0.06209Inherited
Transducin (alpha subunit), insertion domain0.06209Inherited
Chromo domain-like0.06209Inherited
Clavaminate synthase-like0.06586Inherited
Homeodomain-like0.12Inherited
Cyclin-like0.8929Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
50692,54585
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 0Direct
    54585,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    54001,49758
  • 54001 - Cysteine proteinases
  • 49758 - Calpain large subunit, middle domain (domain III)
  • 0.0000003598Direct
    54849,52029
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.000003799Direct
    48592,54849
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 0.000003799Direct
    81333,81333
  • 81333 - F1F0 ATP synthase subunit C
  • 81333 - F1F0 ATP synthase subunit C
  • 0.00001888Direct
    46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.0005225Direct
    48065,50729
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0.0007779Direct
    56968,48431
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 48431 - Lipovitellin-phosvitin complex, superhelical domain
  • 0.01315Inherited
    52540,50447
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 0.01315Inherited
    48431,56968
  • 48431 - Lipovitellin-phosvitin complex, superhelical domain
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 0.01315Inherited
    48726,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.02871Inherited
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.05185Inherited
    47895,52540
  • 47895 - Transducin (alpha subunit), insertion domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.06209Inherited
    47954,47954
  • 47954 - Cyclin-like
  • 47954 - Cyclin-like
  • 0.7272Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    50692,54585,52540
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    54585,52540,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    48592,54849,52029
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.000003799Direct
    46966,46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.0002406Direct
    57716,57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.00164Inherited
    56968,48431,56968
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 48431 - Lipovitellin-phosvitin complex, superhelical domain
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 0.01315Inherited
    48726,48726,49265
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.06209Inherited
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.09808Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)