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Worm Phenotype (WP): cell component morphology variant

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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)

Shortest distance to current term (+ for parents, - for children) WP term [WP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   Variant [WBPhenotype:0000886] <2>
+ + 2:   morphology variant [WBPhenotype:0000520] <5>(443|528) (444|229|63)
+ 1:   cell morphology variant [WBPhenotype:0000533] <10>(104|103) (106|55|17)
0:   cell component morphology variant [WBPhenotype:0002089] <17>(84|85) (84|42|9)
- 1:   nuclear appearance variant [WBPhenotype:0001028] <7>(7|9) (7|4|0)
- 1:   cell organization biogenesis variant [WBPhenotype:0010002] <5>(40|43) (41|18|4)
- 1:   cilia morphology variant [WBPhenotype:0000615] <5>(1|0) (1|1|0)
- 1:   germ cell cytoplasmic morphology variant [WBPhenotype:0001300] <3>(11|8) (11|5|2)
- 1:   mitochondria morphology variant [WBPhenotype:0001401] <3>(17|18) (18|10|2)
- 1:   cell membrane morphology variant [WBPhenotype:0001399] <2>(2|1) (2|0|0)
- 1:   extracellular matrix variant [WBPhenotype:0001523] <2>(0|0) (0|0|0)
- 1:   synapse morphology variant [WBPhenotype:0000616] <2>(6|5) (6|2|1)
- 1:   vesicle organization variant [WBPhenotype:0001671] <2>(15|13) (15|5|1)
- 1:   endoplasmic reticulum morphology variant [WBPhenotype:0001880] <1>(3|4) (3|3|2)
- 1:   neurite morphology variant [WBPhenotype:0001398] <1>(12|8) (13|4|2)
- 1:   annulae morphology variant [WBPhenotype:0001517](1|1) (1|0|0)
- 1:   golgi apparatus morphology variant [WBPhenotype:0002096](0|0) (0|0|0)
- 1:   lysosome morphology variant [WBPhenotype:0002097](2|2) (2|0|0)
- 1:   lysosome-related organelle morphology variant [WBPhenotype:0002095](7|7) (7|3|0)
- 1:   peroxisome morphology variant [WBPhenotype:0001263](0|0) (0|0|0)
- 1:   struts variant [WBPhenotype:0001515](0|0) (0|0|0)


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Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Zn-finger domain of Sec23/240Direct
Sec1/munc18-like (SM) proteins0Direct
Subdomain of clathrin and coatomer appendage domain0Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0Direct
LEM domain0Direct
Profilin (actin-binding protein)0Direct
Heme-dependent catalase-like0Direct
RBP11-like subunits of RNA polymerase0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
GroEL equatorial domain-like0Direct
C-terminal, gelsolin-like domain of Sec23/240Direct
GroEL-intermediate domain like0Direct
Helical domain of Sec23/240Direct
Skp1 dimerisation domain-like0.000000000351Direct
Tubulin C-terminal domain-like0.0000000113Direct
Tubulin nucleotide-binding domain-like0.00000005751Direct
SNARE-like0.00000006867Direct
Class II aaRS and biotin synthetases0.0000323Direct
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.00009579Direct
Intermediate filament protein, coiled coil region0.0001392Direct
Lamin A/C globular tail domain0.0001392Direct
ValRS/IleRS/LeuRS editing domain0.0003162Direct
Ribosomal proteins S24e, L23 and L15e0.0003162Direct
Translation proteins SH3-like domain0.0003456Direct
Class II aaRS ABD-related0.0009961Direct
Ferredoxin reductase-like, C-terminal NADP-linked domain0.0009961Direct
Calpain large subunit, middle domain (domain III)0.0009961Direct
Activating enzymes of the ubiquitin-like proteins0.0009961Direct
Riboflavin synthase domain-like0.0009961Direct
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.001358Inherited
Cdc48 domain 2-like0.001803Inherited
beta-sandwich domain of Sec23/240.001803Inherited
ADC-like0.001803Inherited
Zn-binding ribosomal proteins0.00429Inherited
F1F0 ATP synthase subunit C0.007125Inherited
CAD & PB1 domains0.007125Inherited
L30e-like0.01719Inherited
Histone-fold0.01727Inherited
Cyclin-like0.02011Inherited
Nucleic acid-binding proteins0.02749Inherited
EGF/Laminin0.03268Inherited
SH2 domain0.05474Inherited
Actin-like ATPase domain0.07696Inherited
Sm-like ribonucleoproteins0.15Inherited
PDZ domain-like0.1727Inherited
GTPase activation domain, GAP0.1968Inherited
Ribosomal protein S5 domain 2-like0.2084Inherited
GroEL apical domain-like0.2446Inherited
SNARE fusion complex0.2446Inherited
"Winged helix" DNA-binding domain0.2485Inherited
ARM repeat0.2587Inherited
P-loop containing nucleoside triphosphate hydrolases0.2728Inherited
PH domain-like0.2854Inherited
Concanavalin A-like lectins/glucanases0.2856Inherited
Nucleotidylyl transferase0.287Inherited
C2 domain (Calcium/lipid-binding domain, CaLB)0.3293Inherited
t-snare proteins0.3364Inherited
DBL homology domain (DH-domain)0.3364Inherited
SH3-domain0.3883Inherited
SAM/Pointed domain0.3936Inherited
Prefoldin0.4577Inherited
SMAD/FHA domain0.4577Inherited
Second domain of FERM0.4577Inherited
(Phosphotyrosine protein) phosphatases II0.5057Inherited
TPR-like0.535Inherited
WD40 repeat-like0.5621Inherited
Integrin domains0.6167Inherited
Cystine-knot cytokines0.6167Inherited
PYP-like sensor domain (PAS domain)0.6167Inherited
Tropomyosin0.7348Inherited
POZ domain0.7424Inherited
Immunoglobulin0.7907Inherited
dsRNA-binding domain-like0.7982Inherited
Spectrin repeat0.7982Inherited
Protein kinase-like (PK-like)0.803Inherited
Fibronectin type III0.8141Inherited
CCCH zinc finger0.8921Inherited
Calponin-homology domain, CH-domain0.9101Inherited
Voltage-gated potassium channels0.9147Inherited
Cysteine-rich domain0.9177Inherited
EF-hand1Inherited
NAD(P)-binding Rossmann-fold domains1Inherited
RNA-binding domain, RBD1Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
LEM domain0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Anticodon-binding domain of Class II aaRS0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Profilin (actin-binding protein)0Direct
beta-sandwich domain of Sec23/240Direct
Trunk domain of Sec23/240Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0Direct
Helical domain of Sec23/240Direct
Group II chaperonin (CCT, TRIC), intermediate domain0Direct
Phoshoinositide 3-kinase (PI3K) helical domain0Direct
Heme-dependent catalases0Direct
Zn-finger domain of Sec23/240Direct
Integrin domains0Direct
C-terminal, gelsolin-like domain of Sec23/240Direct
Group II chaperonin (CCT, TRIC), ATPase domain0Direct
Sec1/munc18-like (SM) proteins0Direct
Skp1 dimerisation domain-like0.0000000009924Direct
Tubulin, C-terminal domain0.00000008367Direct
BCR-homology GTPase activation domain (BH-domain)0.0000001823Direct
Tubulin, GTPase domain0.0000003578Direct
Proteasome subunits0.0000003712Direct
Pumilio repeat0.000006851Direct
PDZ domain0.000008036Direct
Clathrin adaptor core protein0.0000222Direct
Clathrin coat assembly domain0.0000222Direct
Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain0.00003231Direct
Armadillo repeat0.00009741Direct
RecA protein-like (ATPase-domain)0.0001119Direct
Laminin-type module0.0001119Direct
DNA replication initiator (cdc21/cdc54) N-terminal domain0.0001119Direct
Intermediate filament protein, coiled coil region0.0003693Direct
Extended AAA-ATPase domain0.0005249Direct
ValRS/IleRS/LeuRS editing domain0.0005556Direct
Ubiquitin activating enzymes (UBA)0.0005556Direct
BAR domain0.0005556Direct
Smc hinge domain0.0005556Direct
Prefoldin0.0006172Direct
Calpain large subunit, middle domain (domain III)0.001968Inherited
Cdc48 N-terminal domain-like0.002723Inherited
Anticodon-binding domain0.002723Inherited
Ferredoxin reductase FAD-binding domain-like0.002723Inherited
Cdc48 domain 2-like0.002723Inherited
Nucleosome core histones0.004611Inherited
F1F0 ATP synthase subunit C0.0107Inherited
DEP domain0.0107Inherited
Transforming growth factor (TGF)-beta0.0107Inherited
Translational machinery components0.01572Inherited
Laminin G-like module0.01703Inherited
Cyclin0.0223Inherited
Class I aminoacyl-tRNA synthetases (RS), catalytic domain0.0223Inherited
Cold shock DNA-binding domain-like0.03601Inherited
DNA polymerase I0.04881Inherited
SH2 domain0.04968Inherited
Calpain large subunit, catalytic domain (domain II)0.06011Inherited
G proteins0.06701Inherited
Elongation factors0.06814Inherited
Actin/HSP700.09827Inherited
DnaQ-like 3'-5' exonuclease0.1077Inherited
I set domains0.1167Inherited
FHA domain0.1316Inherited
BTB/POZ domain0.1852Inherited
Sm motif of small nuclear ribonucleoproteins, SNRNP0.2289Inherited
Group II chaperonin (CCT, TRIC), apical domain0.2698Inherited
SNARE fusion complex0.2698Inherited
DBL homology domain (DH-domain)0.3177Inherited
t-snare proteins0.3177Inherited
SH3-domain0.3771Inherited
Pleckstrin-homology domain (PH domain)0.3853Inherited
Second domain of FERM0.4384Inherited
Third domain of FERM0.5117Inherited
First domain of FERM0.5956Inherited
LIM domain0.7171Inherited
Ubiquitin-related0.7171Inherited
Tropomyosin0.7171Inherited
Spectrin repeat0.7819Inherited
WD40-repeat0.8024Inherited
Fibronectin type III0.8042Inherited
Protein kinases, catalytic subunit0.8154Inherited
Motor proteins0.8431Inherited
CCCH zinc finger0.8786Inherited
Calponin-homology domain, CH-domain0.899Inherited
Calmodulin-like1Inherited
Voltage-gated potassium channels1Inherited
Canonical RBD1Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
LEM domain0Direct
GroEL-intermediate domain like0Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Sec1/munc18-like (SM) proteins0Direct
Helical domain of Sec23/240Direct
GroEL equatorial domain-like0Direct
RBP11-like subunits of RNA polymerase0Direct
Profilin (actin-binding protein)0Direct
C-terminal, gelsolin-like domain of Sec23/240Direct
Subdomain of clathrin and coatomer appendage domain0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Zn-finger domain of Sec23/240Direct
Heme-dependent catalase-like0Direct
Skp1 dimerisation domain-like0.0000000002784Direct
Tubulin C-terminal domain-like0.00000000901Direct
Tubulin nucleotide-binding domain-like0.00000004602Direct
SNARE-like0.00000005496Direct
Class II aaRS and biotin synthetases0.00002637Direct
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.00007849Direct
Intermediate filament protein, coiled coil region0.0001142Direct
Lamin A/C globular tail domain0.0001142Direct
ValRS/IleRS/LeuRS editing domain0.0002605Direct
Ribosomal proteins S24e, L23 and L15e0.0002605Direct
Translation proteins SH3-like domain0.0002849Direct
Calpain large subunit, middle domain (domain III)0.0008292Direct
Riboflavin synthase domain-like0.0008292Direct
Ferredoxin reductase-like, C-terminal NADP-linked domain0.0008292Direct
Activating enzymes of the ubiquitin-like proteins0.0008292Direct
Class II aaRS ABD-related0.0008292Direct
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.001133Inherited
beta-sandwich domain of Sec23/240.001509Inherited
Cdc48 domain 2-like0.001509Inherited
ADC-like0.001509Inherited
Zn-binding ribosomal proteins0.003638Inherited
CAD & PB1 domains0.006082Inherited
F1F0 ATP synthase subunit C0.006082Inherited
L30e-like0.01492Inherited
Histone-fold0.015Inherited
Cyclin-like0.0175Inherited
Nucleic acid-binding proteins0.02408Inherited
EGF/Laminin0.02874Inherited
SH2 domain0.04861Inherited
Actin-like ATPase domain0.06896Inherited
Sm-like ribonucleoproteins0.1368Inherited
PDZ domain-like0.1584Inherited
GTPase activation domain, GAP0.1812Inherited
Ribosomal protein S5 domain 2-like0.1922Inherited
GroEL apical domain-like0.227Inherited
SNARE fusion complex0.227Inherited
"Winged helix" DNA-binding domain0.2307Inherited
ARM repeat0.2407Inherited
P-loop containing nucleoside triphosphate hydrolases0.2544Inherited
PH domain-like0.2668Inherited
Concanavalin A-like lectins/glucanases0.2671Inherited
Nucleotidylyl transferase0.2684Inherited
C2 domain (Calcium/lipid-binding domain, CaLB)0.3097Inherited
DBL homology domain (DH-domain)0.3167Inherited
t-snare proteins0.3167Inherited
SH3-domain0.3678Inherited
SAM/Pointed domain0.3731Inherited
Second domain of FERM0.4367Inherited
Prefoldin0.4367Inherited
SMAD/FHA domain0.4367Inherited
(Phosphotyrosine protein) phosphatases II0.4839Inherited
TPR-like0.5131Inherited
WD40 repeat-like0.5403Inherited
Integrin domains0.5947Inherited
PYP-like sensor domain (PAS domain)0.5947Inherited
Cystine-knot cytokines0.5947Inherited
Tropomyosin0.7146Inherited
POZ domain0.7226Inherited
Immunoglobulin0.7723Inherited
dsRNA-binding domain-like0.7797Inherited
Spectrin repeat0.7797Inherited
Protein kinase-like (PK-like)0.7846Inherited
Fibronectin type III0.7959Inherited
CCCH zinc finger0.8767Inherited
Calponin-homology domain, CH-domain0.8949Inherited
Voltage-gated potassium channels0.8996Inherited
Cysteine-rich domain0.9028Inherited
NAD(P)-binding Rossmann-fold domains1Inherited
EF-hand1Inherited
RNA-binding domain, RBD1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
54849,52029
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0Direct
    49348,55711
  • 49348 - Clathrin adaptor appendage domain
  • 55711 - Subdomain of clathrin and coatomer appendage domain
  • 0Direct
    50692,54585
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 0Direct
    81383,50978
  • 81383 - F-box domain
  • 50978 - WD40 repeat-like
  • 0Direct
    54585,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    81811,82754
  • 81811 - Helical domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0Direct
    82919,53300
  • 82919 - Zn-finger domain of Sec23/24
  • 53300 - vWA-like
  • 0Direct
    48592,54849
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 0Direct
    64356,49447
  • 64356 - SNARE-like
  • 49447 - Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor
  • 0Direct
    52540,47917
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase
  • 0Direct
    49562,48371
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 0Direct
    54695,81382
  • 54695 - POZ domain
  • 81382 - Skp1 dimerisation domain-like
  • 0.0000000003324Direct
    52490,55307
  • 52490 - Tubulin nucleotide-binding domain-like
  • 55307 - Tubulin C-terminal domain-like
  • 0.00000004602Direct
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.0000247Direct
    64593,74853
  • 64593 - Intermediate filament protein, coiled coil region
  • 74853 - Lamin A/C globular tail domain
  • 0.0002518Direct
    54001,49758
  • 54001 - Cysteine proteinases
  • 49758 - Calpain large subunit, middle domain (domain III)
  • 0.0002518Direct
    50677,52374
  • 50677 - ValRS/IleRS/LeuRS editing domain
  • 52374 - Nucleotidylyl transferase
  • 0.0002605Direct
    50978,50978
  • 50978 - WD40 repeat-like
  • 50978 - WD40 repeat-like
  • 0.0006175Direct
    49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.0008292Direct
    47954,47954
  • 47954 - Cyclin-like
  • 47954 - Cyclin-like
  • 0.0012Inherited
    63380,52343
  • 63380 - Riboflavin synthase domain-like
  • 52343 - Ferredoxin reductase-like, C-terminal NADP-linked domain
  • 0.001267Inherited
    55550,50044
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0.001509Inherited
    81333,81333
  • 81333 - F1F0 ATP synthase subunit C
  • 81333 - F1F0 ATP synthase subunit C
  • 0.001509Inherited
    50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0.003638Inherited
    50249,55681
  • 50249 - Nucleic acid-binding proteins
  • 55681 - Class II aaRS and biotin synthetases
  • 0.006082Inherited
    57625,57625
  • 57625 - Invertebrate chitin-binding proteins
  • 57625 - Invertebrate chitin-binding proteins
  • 0.01492Inherited
    53098,56672
  • 53098 - Ribonuclease H-like
  • 56672 - DNA/RNA polymerases
  • 0.01492Inherited
    52540,50447
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 0.02279Inherited
    52374,47323
  • 52374 - Nucleotidylyl transferase
  • 47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
  • 0.02899Inherited
    53067,53067
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 0.06896Inherited
    90229,90229
  • 90229 - CCCH zinc finger
  • 90229 - CCCH zinc finger
  • 0.0738Inherited
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.4142Inherited
    47031,50729
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.4367Inherited
    48065,50729
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0.4367Inherited
    55550,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.4489Inherited
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.5103Inherited
    54236,47031
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 0.5103Inherited
    48371,48371
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 0.5343Inherited
    48726,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.5887Inherited
    52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.8294Inherited
    48452,48452
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 0.9642Inherited
    57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 1Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    49562,48371,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    50692,54585,52540
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    48592,54849,52029
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0Direct
    54585,52540,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    57625,57625,57625
  • 57625 - Invertebrate chitin-binding proteins
  • 57625 - Invertebrate chitin-binding proteins
  • 57625 - Invertebrate chitin-binding proteins
  • 0.006082Inherited
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.3028Inherited
    57716,57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.3167Inherited
    48726,48726,49265
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.3731Inherited
    54236,47031,50729
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.5103Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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