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Xenopus ANatomical entity (XAN): nervous system

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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: XA Hierarchy (Xenopus anatomy and development from Xenbase frog anatomy ontology)

Shortest distance to current term (+ for parents, - for children) XA term [XA ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   Xenopus anatomical entity [XAO:0000000] <9>
+ + + 3:   whole organism [XAO:0003004] <12>(470|603) (471|338|143)
+ + + 3:   anatomical structure [XAO:0003000] <11>(574|729) (574|397|161)
+ + 2:   anatomical group [XAO:0003001] <2>(426|540) (428|312|132)
+ 1:   anatomical system [XAO:0003002] <19>(302|393) (307|210|91)
0:   nervous system [XAO:0000177] <10>(133|200) (138|113|51)
- 1:   neuron [XAO:0003023] <16>(10|12) (11|3|1)
- 1:   peripheral nervous system [XAO:0000178] <8>(15|14) (15|4|0)
- 1:   nerve [XAO:0003047] <7>(10|10) (10|3|0)
- 1:   central nervous system [XAO:0000215] <6>(129|191) (132|105|48)
- 1:   glial cell [XAO:0004308] <6>(0|0) (0|0|0)
- 1:   sensory system [XAO:0003194] <5>(39|53) (44|27|13)
- 1:   migrating neuroblast [XAO:0004272](0|0) (0|0|0)
- 1:   neural progenitor cell [XAO:0005034](1|1) (1|0|0)
- 1:   neural stem cell [XAO:0005032](0|0) (0|0|0)
- 1:   radial glial cell [XAO:0005031](0|0) (0|0|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Thiamin diphosphate-binding fold (THDP-binding)0Direct
Pentein0Direct
LuxS/MPP-like metallohydrolase0Direct
Zn-binding ribosomal proteins0Direct
A heparin-binding domain0Direct
Amyloid beta a4 protein copper binding domain (domain 2)0Direct
Cytokine0Direct
TGS-like0Direct
TK C-terminal domain-like0Direct
14-3-3 protein0Direct
Endosomal sorting complex assembly domain0Direct
TNF receptor-like0Direct
Nop domain0Direct
Mss4-like0Direct
PriA/YqbF domain0Direct
Phosphoglucomutase, C-terminal domain0Direct
Tim10-like0Direct
CAPPD, an extracellular domain of amyloid beta A4 protein0Direct
HSP90 C-terminal domain0Direct
Myosin phosphatase inhibitor 17kDa protein, CPI-170Direct
alpha-catenin/vinculin-like0Direct
Phosphoglucomutase, first 3 domains0Direct
SWIB/MDM2 domain0Direct
post-AAA+ oligomerization domain-like0Direct
USP8 N-terminal domain-like0Direct
SRF-like0Direct
DLC0Direct
PLP-binding barrel0Direct
Enolase C-terminal domain-like0Direct
F1F0 ATP synthase subunit C0Direct
Mib/herc2 domain-like0Direct
Isocitrate/Isopropylmalate dehydrogenase-like0Direct
Oligoxyloglucan reducing end-specific cellobiohydrolase0Direct
BRK domain-like0Direct
ClpS-like0Direct
TAFH domain-like0Direct
Helical domain of Sec23/240Direct
4Fe-4S ferredoxins0Direct
Zn-finger domain of Sec23/240Direct
CCHHC domain0Direct
MAST3 pre-PK domain-like0Direct
Synuclein0Direct
alpha-ketoacid dehydrogenase kinase, N-terminal domain0Direct
GroEL-intermediate domain like0Direct
Families 57/38 glycoside transferase middle domain0Direct
Bacterial exopeptidase dimerisation domain0Direct
PAH2 domain0Direct
Hedgehog/DD-peptidase0Direct
Hook domain0Direct
Transducin (heterotrimeric G protein), gamma chain0Direct
Subunits of heterodimeric actin filament capping protein Capz0Direct
beta-sandwich domain of Sec23/240Direct
Ribulose-phoshate binding barrel0Direct
Nuclear receptor coactivator interlocking domain0Direct
Enolase N-terminal domain-like0Direct
DnaJ/Hsp40 cysteine-rich domain0Direct
BEACH domain0Direct
Cullin homology domain0Direct
Stathmin0Direct
Subdomain of clathrin and coatomer appendage domain0Direct
NAP-like0Direct
Aconitase iron-sulfur domain0Direct
Acyl-CoA binding protein0Direct
ARID-like0Direct
Thioesterase/thiol ester dehydrase-isomerase0Direct
Clathrin adaptor appendage domain0Direct
SPOC domain-like0Direct
Dimeric alpha+beta barrel0Direct
G protein-binding domain0Direct
eIF1-like0Direct
ACP-like0Direct
Glutamine synthetase/guanido kinase0Direct
RNase III domain-like0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0Direct
Notch domain0Direct
Glycoside hydrolase/deacetylase0Direct
ThrRS/AlaRS common domain0Direct
AraD/HMP-PK domain-like0Direct
Ligand-binding domain in the NO signalling and Golgi transport0Direct
Alanine racemase C-terminal domain-like0Direct
Transcription factor STAT-4 N-domain0Direct
GYF domain0Direct
HSP40/DnaJ peptide-binding domain0Direct
Sec1/munc18-like (SM) proteins0Direct
SMAD MH1 domain0Direct
Moesin tail domain0Direct
Succinyl-CoA synthetase domains0Direct
Guanido kinase N-terminal domain0Direct
Cysteine-rich DNA binding domain, (DM domain)0Direct
LeuD/IlvD-like0Direct
Aminomethyltransferase beta-barrel domain0Direct
Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain0Direct
Cysteine alpha-hairpin motif0Direct
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0Direct
I/LWEQ domain0Direct
Delta-sleep-inducing peptide immunoreactive peptide0Direct
Cadherin-like0.0009613Direct
RNA-binding domain, RBD0.001509Inherited
Ubiquitin-like0.001848Inherited
Second domain of FERM0.002014Inherited
HMG-box0.002154Inherited
ARM repeat0.003477Inherited
HLH, helix-loop-helix DNA-binding domain0.004742Inherited
UBC-like0.004977Inherited
Frizzled cysteine-rich domain0.009809Inherited
Tubulin C-terminal domain-like0.01286Inherited
Homeodomain-like0.02272Inherited
PH domain-like0.05564Inherited
Tubulin nucleotide-binding domain-like0.06098Inherited
Transducin (alpha subunit), insertion domain0.06316Inherited
Growth factor receptor domain0.09399Inherited
Spectrin repeat0.1083Inherited
lambda repressor-like DNA-binding domains0.1224Inherited
PYP-like sensor domain (PAS domain)0.1294Inherited
Voltage-gated potassium channels0.1421Inherited
Orange domain-like0.1673Inherited
Proton glutamate symport protein0.197Inherited
"Winged helix" DNA-binding domain0.2094Inherited
Galactose-binding domain-like0.3577Inherited
Sema domain0.3922Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.4702Inherited
Plexin repeat0.5044Inherited
p53-like transcription factors0.6347Inherited
Kazal-type serine protease inhibitors0.6934Inherited
DNA-binding domain0.7227Inherited
POZ domain0.8061Inherited
E set domains0.9128Inherited
Intermediate filament protein, coiled coil region0.9264Inherited
gamma-Crystallin-like0.976Inherited
Family A G protein-coupled receptor-like1Inherited
EGF/Laminin1Inherited
Cystine-knot cytokines1Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
TRAPP components0Direct
alpha-catenin/vinculin0Direct
GS domain0Direct
Clathrin adaptor appendage, alpha and beta chain-specific domain0Direct
alpha-mannosidase, domain 20Direct
Mib/herc2 domain0Direct
Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A0Direct
Other IPT/TIG domains0Direct
GDI-like N domain0Direct
Carboxylesterase/thioesterase 10Direct
MSP-like0Direct
Amyloid beta a4 protein copper binding domain (domain 2)0Direct
Group II chaperonin (CCT, TRIC), intermediate domain0Direct
BRK domain-like0Direct
C-terminal, gelsolin-like domain of Sec23/240Direct
DNA ligase0Direct
Phoshoinositide 3-kinase (PI3K) helical domain0Direct
Ferritin0Direct
Fibroblast growth factors (FGF)0Direct
SMAD domain0Direct
HCDH C-domain-like0Direct
TNF receptor-like0Direct
MPP-like0Direct
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain0Direct
PA domain0Direct
CUE domain0Direct
DJ-1/PfpI0Direct
Glycosyl transferases group 10Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
DIX domain0Direct
Hook domain0Direct
Anticodon-binding domain of Class II aaRS0Direct
B56-like0Direct
HD domain0Direct
Heat shock protein 90, HSP90, N-terminal domain0Direct
Phosphoglucomutase, C-terminal domain0Direct
RPR domain (SMART 00582 )0Direct
AraD-like aldolase/epimerase0Direct
F1F0 ATP synthase subunit C0Direct
Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain0Direct
CAPPD, an extracellular domain of amyloid beta A4 protein0Direct
DNA polymerase III clamp loader subunits, C-terminal domain0Direct
Nuclear receptor coactivator interlocking domain0Direct
4HBT-like0Direct
UDP-glucose pyrophosphorylase0Direct
Transducin (heterotrimeric G protein), gamma chain0Direct
Cytochrome b50Direct
Pumilio repeat0Direct
P4 origin-binding domain-like0Direct
Myosin phosphatase inhibitor 17kDa protein, CPI-170Direct
Cullin repeat0Direct
NTF2-like0Direct
SMAD MH1 domain0Direct
Guanido kinase N-terminal domain0Direct
TAFH domain-like0Direct
A heparin-binding domain0Direct
Cyclin A/CDK2-associated p19, Skp20Direct
Cofactor-dependent phosphoglycerate mutase0Direct
Autophagin-like0Direct
S-adenosylhomocystein hydrolase0Direct
SRF-like0Direct
PAS domain of steroid receptor coactivator 1A, NCo-A10Direct
Variant RING domain0Direct
Transferrin0Direct
Notch domain0Direct
Alanine racemase-like, N-terminal domain0Direct
Glyoxalase II (hydroxyacylglutathione hydrolase)0Direct
Eukaryotic ODC-like0Direct
Transcription factor STAT-4 N-domain0Direct
RuBisCo LSMT catalytic domain0Direct
Sec1/munc18-like (SM) proteins0Direct
DnaJ/Hsp40 cysteine-rich domain0Direct
Ubiquitin carboxyl-terminal hydrolase UCH-L0Direct
I/LWEQ domain0Direct
Guanido kinase catalytic domain0Direct
Acyl-CoA binding protein0Direct
Phosphoribosylpyrophosphate synthetase-like0Direct
a tRNA synthase domain0Direct
HSP90 C-terminal domain0Direct
alpha-mannosidase, C-terminal domain0Direct
Cell cycle control phosphatase, catalytic domain0Direct
SIAH, seven in absentia homolog0Direct
beta-sandwich domain of Sec23/240Direct
Gonadodropin/Follitropin0Direct
Alpha-adaptin ear subdomain-like0Direct
NIPSNAP0Direct
HAT/Suf repeat0Direct
Moesin tail domain0Direct
Threonyl-tRNA synthetase (ThrRS), second 'additional' domain0Direct
Neutral endopeptidase (neprilysin)0Direct
DLC0Direct
Trunk domain of Sec23/240Direct
HSP40/DnaJ peptide-binding domain0Direct
Ran-binding domain0Direct
PreBEACH PH-like domain0Direct
Cullin homology domain0Direct
SWIB/MDM2 domain0Direct
gamma-adaptin C-terminal appendage domain-like0Direct
Chromo barrel domain0Direct
1,3-glucuronyltransferase0Direct
Phoshatidylinositol transfer protein, PITP0Direct
ZZ domain0Direct
NAP-like0Direct
Tim10/DDP0Direct
DNA gyrase/MutL, N-terminal domain0Direct
Group II chaperonin (CCT, TRIC), apical domain0Direct
Delta-sleep-inducing peptide immunoreactive peptide0Direct
Branched-chain alpha-keto acid dehydrogenase PP module0Direct
Zn-finger domain of Sec23/240Direct
Enolase N-terminal domain-like0Direct
USP8 N-terminal domain-like0Direct
DNA gyrase/MutL, second domain0Direct
14-3-3 protein0Direct
Cysteine-rich DNA binding domain, (DM domain)0Direct
Aminomethyltransferase beta-barrel domain0Direct
SH3BGR (SH3-binding, glutamic acid-rich protein-like)0Direct
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain0Direct
Arrestin/Vps26-like0Direct
ARID domain0Direct
Succinyl-CoA synthetase domains0Direct
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0Direct
Stathmin0Direct
Helical domain of Sec23/240Direct
A20-like zinc finger0Direct
CCHHC domain0Direct
Bacterial exopeptidase dimerisation domain0Direct
APC10-like0Direct
Synuclein0Direct
Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta0Direct
Noggin0Direct
IF2B-like0Direct
alpha-ketoacid dehydrogenase kinase, N-terminal domain0Direct
eIF1-like0Direct
Sedlin (SEDL)0Direct
Cytidylyltransferase0Direct
LeuD-like0Direct
Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain0Direct
Linker histone H1/H50Direct
TRASH domain0Direct
Phosphoglucomutase, first 3 domains0Direct
Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain0Direct
Aconitase iron-sulfur domain0Direct
BEACH domain0Direct
Hedgehog (development protein), N-terminal signaling domain0Direct
Hsp90 middle domain0Direct
Extracellular domain of cell surface receptors0Direct
alpha-ketoacid dehydrogenase kinase, C-terminal domain0Direct
Dimeric isocitrate & isopropylmalate dehydrogenases0Direct
alpha-mannosidase0Direct
Branched-chain alpha-keto acid dehydrogenase Pyr module0Direct
Adenain-like0Direct
Ephrin receptor ligand binding domain0Direct
Protein-L-isoaspartyl O-methyltransferase0Direct
PAH2 domain0Direct
Nop domain0Direct
MAST3 pre-PK domain-like0Direct
SCF ubiquitin ligase complex WHB domain0Direct
Canonical RBD0.0001088Direct
UBC-related0.0003952Direct
Cadherin0.00125Inherited
Third domain of FERM0.001666Inherited
HMG-box0.002138Inherited
Second domain of FERM0.003235Inherited
HLH, helix-loop-helix DNA-binding domain0.005238Inherited
Frizzled cysteine-rich domain0.008931Inherited
Tubulin, C-terminal domain0.01177Inherited
Tubulin, GTPase domain0.01177Inherited
Laminin G-like module0.0296Inherited
G proteins0.03173Inherited
Growth factor receptor domain0.035Inherited
Transducin (alpha subunit), insertion domain0.05782Inherited
Homeodomain0.08074Inherited
Voltage-gated potassium channels0.08414Inherited
LIM domain0.0947Inherited
Enabled/VASP homology 1 domain (EVH1 domain)0.09539Inherited
POU-specific domain0.149Inherited
Hairy Orange domain0.1555Inherited
Spectrin repeat0.1757Inherited
Proton glutamate symport protein0.183Inherited
Glutathione peroxidase-like0.1881Inherited
Paired domain0.1977Inherited
Forkhead DNA-binding domain0.2333Inherited
Hypoxia-inducible factor Hif2a, C-terminal domain0.2799Inherited
ets domain0.283Inherited
Higher-molecular-weight phosphotyrosine protein phosphatases0.3042Inherited
T-box0.3075Inherited
L domain0.3128Inherited
Sema domain0.3169Inherited
Tetramerization domain of potassium channels0.4012Inherited
I set domains0.4697Inherited
Tandem AAA-ATPase domain0.4787Inherited
Plexin repeat0.4992Inherited
Ovomucoid domain III-like0.504Inherited
Ephrin ectodomain0.622Inherited
Classic zinc finger, C2H20.6906Inherited
Erythroid transcription factor GATA-10.8399Inherited
Intermediate filament protein, coiled coil region0.9189Inherited
Crystallins/Ca-binding development proteins0.9592Inherited
Transforming growth factor (TGF)-beta0.9986Inherited
Rhodopsin-like1Inherited


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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
14-3-3 protein0Direct
TK C-terminal domain-like0Direct
Cytokine0Direct
TGS-like0Direct
Phosphoglucomutase, first 3 domains0Direct
Synuclein0Direct
Tim10-like0Direct
Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain0Direct
ACP-like0Direct
Aconitase iron-sulfur domain0Direct
PLP-binding barrel0Direct
4Fe-4S ferredoxins0Direct
Enolase N-terminal domain-like0Direct
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0Direct
Aminomethyltransferase beta-barrel domain0Direct
Notch domain0Direct
Sec1/munc18-like (SM) proteins0Direct
Transducin (heterotrimeric G protein), gamma chain0Direct
HSP40/DnaJ peptide-binding domain0Direct
alpha-ketoacid dehydrogenase kinase, N-terminal domain0Direct
HSP90 C-terminal domain0Direct
G protein-binding domain0Direct
Oligoxyloglucan reducing end-specific cellobiohydrolase0Direct
Phosphoglucomutase, C-terminal domain0Direct
Glycoside hydrolase/deacetylase0Direct
Bacterial exopeptidase dimerisation domain0Direct
Hook domain0Direct
beta-sandwich domain of Sec23/240Direct
Thiamin diphosphate-binding fold (THDP-binding)0Direct
CCHHC domain0Direct
ThrRS/AlaRS common domain0Direct
Thioesterase/thiol ester dehydrase-isomerase0Direct
Glutamine synthetase/guanido kinase0Direct
Myosin phosphatase inhibitor 17kDa protein, CPI-170Direct
Subunits of heterodimeric actin filament capping protein Capz0Direct
TAFH domain-like0Direct
SRF-like0Direct
Guanido kinase N-terminal domain0Direct
SMAD MH1 domain0Direct
Amyloid beta a4 protein copper binding domain (domain 2)0Direct
Succinyl-CoA synthetase domains0Direct
alpha-catenin/vinculin-like0Direct
ClpS-like0Direct
Zn-binding ribosomal proteins0Direct
eIF1-like0Direct
ARID-like0Direct
BEACH domain0Direct
A heparin-binding domain0Direct
BRK domain-like0Direct
Zn-finger domain of Sec23/240Direct
Nuclear receptor coactivator interlocking domain0Direct
Pentein0Direct
Moesin tail domain0Direct
DnaJ/Hsp40 cysteine-rich domain0Direct
Cullin homology domain0Direct
PriA/YqbF domain0Direct
Cysteine-rich DNA binding domain, (DM domain)0Direct
Alanine racemase C-terminal domain-like0Direct
Stathmin0Direct
GroEL-intermediate domain like0Direct
Subdomain of clathrin and coatomer appendage domain0Direct
Cysteine alpha-hairpin motif0Direct
Helical domain of Sec23/240Direct
SWIB/MDM2 domain0Direct
F1F0 ATP synthase subunit C0Direct
LuxS/MPP-like metallohydrolase0Direct
Mib/herc2 domain-like0Direct
DLC0Direct
Endosomal sorting complex assembly domain0Direct
LeuD/IlvD-like0Direct
USP8 N-terminal domain-like0Direct
Nop domain0Direct
Hedgehog/DD-peptidase0Direct
Ligand-binding domain in the NO signalling and Golgi transport0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
I/LWEQ domain0Direct
Isocitrate/Isopropylmalate dehydrogenase-like0Direct
post-AAA+ oligomerization domain-like0Direct
Delta-sleep-inducing peptide immunoreactive peptide0Direct
AraD/HMP-PK domain-like0Direct
Transcription factor STAT-4 N-domain0Direct
Enolase C-terminal domain-like0Direct
Families 57/38 glycoside transferase middle domain0Direct
Clathrin adaptor appendage domain0Direct
RNase III domain-like0Direct
MAST3 pre-PK domain-like0Direct
NAP-like0Direct
PAH2 domain0Direct
GYF domain0Direct
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0Direct
Ribulose-phoshate binding barrel0Direct
Dimeric alpha+beta barrel0Direct
Mss4-like0Direct
SPOC domain-like0Direct
CAPPD, an extracellular domain of amyloid beta A4 protein0Direct
TNF receptor-like0Direct
Acyl-CoA binding protein0Direct
Cadherin-like0.0007367Direct
RNA-binding domain, RBD0.001164Inherited
Ubiquitin-like0.001427Inherited
Second domain of FERM0.001558Inherited
HMG-box0.001669Inherited
ARM repeat0.00271Inherited
HLH, helix-loop-helix DNA-binding domain0.003708Inherited
UBC-like0.003896Inherited
Frizzled cysteine-rich domain0.007765Inherited
Tubulin C-terminal domain-like0.01024Inherited
Homeodomain-like0.01827Inherited
PH domain-like0.0461Inherited
Eukaryotic type KH-domain (KH-domain type I)0.04828Inherited
Tubulin nucleotide-binding domain-like0.05067Inherited
Transducin (alpha subunit), insertion domain0.05259Inherited
Growth factor receptor domain0.07975Inherited
Spectrin repeat0.09277Inherited
lambda repressor-like DNA-binding domains0.1057Inherited
PYP-like sensor domain (PAS domain)0.112Inherited
Voltage-gated potassium channels0.1236Inherited
Orange domain-like0.1469Inherited
Proton glutamate symport protein0.1745Inherited
"Winged helix" DNA-binding domain0.1863Inherited
Galactose-binding domain-like0.3284Inherited
F-box domain0.3381Inherited
Sema domain0.3618Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.4375Inherited
Plexin repeat0.4707Inherited
P-loop containing nucleoside triphosphate hydrolases0.5342Inherited
p53-like transcription factors0.6007Inherited
Kazal-type serine protease inhibitors0.6591Inherited
DNA-binding domain0.6879Inherited
Fibronectin type III0.6937Inherited
POZ domain0.7747Inherited
Cupredoxins0.8315Inherited
E set domains0.8852Inherited
Intermediate filament protein, coiled coil region0.8987Inherited
gamma-Crystallin-like0.9491Inherited
Family A G protein-coupled receptor-like1Inherited
EGF/Laminin1Inherited
Cystine-knot cytokines1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 0Direct
    54160,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    47220,47220
  • 47220 - alpha-catenin/vinculin-like
  • 47220 - alpha-catenin/vinculin-like
  • 0Direct
    48403,50044
  • 48403 - Ankyrin repeat
  • 50044 - SH3-domain
  • 0Direct
    47473,57889
  • 47473 - EF-hand
  • 57889 - Cysteine-rich domain
  • 0Direct
    69012,55874
  • 69012 - alpha-ketoacid dehydrogenase kinase, N-terminal domain
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 0Direct
    63501,50242
  • 63501 - Frizzled cysteine-rich domain
  • 50242 - TIMP-like
  • 0Direct
    53187,55031
  • 53187 - Zn-dependent exopeptidases
  • 55031 - Bacterial exopeptidase dimerisation domain
  • 0Direct
    56491,89811
  • 56491 - A heparin-binding domain
  • 89811 - Amyloid beta a4 protein copper binding domain (domain 2)
  • 0Direct
    52540,48019
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 48019 - post-AAA+ oligomerization domain-like
  • 0Direct
    47473,103506
  • 47473 - EF-hand
  • 103506 - Mitochondrial carrier
  • 0Direct
    52540,46785
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    49562,53300
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 53300 - vWA-like
  • 0Direct
    53223,51735
  • 53223 - Aminoacid dehydrogenase-like, N-terminal domain
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0Direct
    47095,47095
  • 47095 - HMG-box
  • 47095 - HMG-box
  • 0Direct
    75632,46785
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    53738,53738
  • 53738 - Phosphoglucomutase, first 3 domains
  • 53738 - Phosphoglucomutase, first 3 domains
  • 0Direct
    57196,49899
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    81324,53850
  • 81324 - Voltage-gated potassium channels
  • 53850 - Periplasmic binding protein-like II
  • 0Direct
    56059,52210
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 52210 - Succinyl-CoA synthetase domains
  • 0Direct
    54631,54631
  • 54631 - CBS-domain pair
  • 54631 - CBS-domain pair
  • 0Direct
    53300,81995
  • 53300 - vWA-like
  • 81995 - beta-sandwich domain of Sec23/24
  • 0Direct
    57440,50494
  • 57440 - Kringle-like
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    48592,54849
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 0Direct
    50729,57889
  • 50729 - PH domain-like
  • 57889 - Cysteine-rich domain
  • 0Direct
    63411,63411
  • 63411 - LuxS/MPP-like metallohydrolase
  • 63411 - LuxS/MPP-like metallohydrolase
  • 0Direct
    47370,47370
  • 47370 - Bromodomain
  • 47370 - Bromodomain
  • 0Direct
    103637,103637
  • 103637 - CCHHC domain
  • 103637 - CCHHC domain
  • 0Direct
    48065,103657
  • 48065 - DBL homology domain (DH-domain)
  • 103657 - BAR/IMD domain-like
  • 0Direct
    88713,88688
  • 88713 - Glycoside hydrolase/deacetylase
  • 88688 - Families 57/38 glycoside transferase middle domain
  • 0Direct
    117281,50965
  • 117281 - Kelch motif
  • 50965 - Galactose oxidase, central domain
  • 0Direct
    57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0Direct
    57424,57184
  • 57424 - LDL receptor-like module
  • 57184 - Growth factor receptor domain
  • 0Direct
    53732,52016
  • 53732 - Aconitase iron-sulfur domain
  • 52016 - LeuD/IlvD-like
  • 0Direct
    57184,49899
  • 57184 - Growth factor receptor domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    48726,56436
  • 48726 - Immunoglobulin
  • 56436 - C-type lectin-like
  • 0Direct
    48350,50729
  • 48350 - GTPase activation domain, GAP
  • 50729 - PH domain-like
  • 0Direct
    54160,54160
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 0Direct
    51419,50621
  • 51419 - PLP-binding barrel
  • 50621 - Alanine racemase C-terminal domain-like
  • 0Direct
    57938,49493
  • 57938 - DnaJ/Hsp40 cysteine-rich domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 0Direct
    50447,50465
  • 50447 - Translation proteins
  • 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
  • 0Direct
    54160,57850
  • 54160 - Chromo domain-like
  • 57850 - RING/U-box
  • 0Direct
    48371,46785
  • 48371 - ARM repeat
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    49348,55711
  • 49348 - Clathrin adaptor appendage domain
  • 55711 - Subdomain of clathrin and coatomer appendage domain
  • 0Direct
    52540,53254
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 53254 - Phosphoglycerate mutase-like
  • 0Direct
    57889,50729
  • 57889 - Cysteine-rich domain
  • 50729 - PH domain-like
  • 0Direct
    52518,52922
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 52922 - TK C-terminal domain-like
  • 0Direct
    74788,75632
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 0Direct
    50729,81837
  • 50729 - PH domain-like
  • 81837 - BEACH domain
  • 0Direct
    82919,53300
  • 82919 - Zn-finger domain of Sec23/24
  • 53300 - vWA-like
  • 0Direct
    81995,81811
  • 81995 - beta-sandwich domain of Sec23/24
  • 81811 - Helical domain of Sec23/24
  • 0Direct
    47473,57850
  • 47473 - EF-hand
  • 57850 - RING/U-box
  • 0Direct
    54637,54637
  • 54637 - Thioesterase/thiol ester dehydrase-isomerase
  • 54637 - Thioesterase/thiol ester dehydrase-isomerase
  • 0Direct
    52821,52799
  • 52821 - Rhodanese/Cell cycle control phosphatase
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    69065,54768
  • 69065 - RNase III domain-like
  • 54768 - dsRNA-binding domain-like
  • 0Direct
    57535,57196
  • 57535 - Complement control module/SCR domain
  • 57196 - EGF/Laminin
  • 0Direct
    46565,57938
  • 46565 - Chaperone J-domain
  • 57938 - DnaJ/Hsp40 cysteine-rich domain
  • 0Direct
    50998,50978
  • 50998 - Quinoprotein alcohol dehydrogenase-like
  • 50978 - WD40 repeat-like
  • 0Direct
    81811,82754
  • 81811 - Helical domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0Direct
    49562,48371
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 0Direct
    57196,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0Direct
    52540,51045
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51045 - WW domain
  • 0Direct
    49493,49493
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 0Direct
    57196,100895
  • 57196 - EGF/Laminin
  • 100895 - Kazal-type serine protease inhibitors
  • 0Direct
    53850,53850
  • 53850 - Periplasmic binding protein-like II
  • 53850 - Periplasmic binding protein-like II
  • 0Direct
    49899,48726
  • 49899 - Concanavalin A-like lectins/glucanases
  • 48726 - Immunoglobulin
  • 0Direct
    52540,47917
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase
  • 0Direct
    100895,47473
  • 100895 - Kazal-type serine protease inhibitors
  • 47473 - EF-hand
  • 0Direct
    57535,49854
  • 57535 - Complement control module/SCR domain
  • 49854 - Spermadhesin, CUB domain
  • 0Direct
    55874,54211
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0Direct
    50044,50156
  • 50044 - SH3-domain
  • 50156 - PDZ domain-like
  • 0Direct
    57863,48403
  • 57863 - ArfGap/RecO-like zinc finger
  • 48403 - Ankyrin repeat
  • 0Direct
    56436,57535
  • 56436 - C-type lectin-like
  • 57535 - Complement control module/SCR domain
  • 0Direct
    57184,49265
  • 57184 - Growth factor receptor domain
  • 49265 - Fibronectin type III
  • 0Direct
    103025,101790
  • 103025 - Folate-binding domain
  • 101790 - Aminomethyltransferase beta-barrel domain
  • 0Direct
    54452,48726
  • 54452 - MHC antigen-recognition domain
  • 48726 - Immunoglobulin
  • 0Direct
    81271,55186
  • 81271 - TGS-like
  • 55186 - ThrRS/AlaRS common domain
  • 0Direct
    57903,51197
  • 57903 - FYVE/PHD zinc finger
  • 51197 - Clavaminate synthase-like
  • 0Direct
    53738,55957
  • 53738 - Phosphoglucomutase, first 3 domains
  • 55957 - Phosphoglucomutase, C-terminal domain
  • 0Direct
    54849,52029
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0Direct
    48034,55931
  • 48034 - Guanido kinase N-terminal domain
  • 55931 - Glutamine synthetase/guanido kinase
  • 0Direct
    52518,52518
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 0Direct
    56112,47769
  • 56112 - Protein kinase-like (PK-like)
  • 47769 - SAM/Pointed domain
  • 0Direct
    57903,47370
  • 57903 - FYVE/PHD zinc finger
  • 47370 - Bromodomain
  • 0Direct
    56112,48371
  • 56112 - Protein kinase-like (PK-like)
  • 48371 - ARM repeat
  • 0Direct
    57184,100895
  • 57184 - Growth factor receptor domain
  • 100895 - Kazal-type serine protease inhibitors
  • 0Direct
    51045,50156
  • 51045 - WW domain
  • 50156 - PDZ domain-like
  • 0Direct
    57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0Direct
    49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.001268Inherited
    47031,50729
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.004435Inherited
    52490,55307
  • 52490 - Tubulin nucleotide-binding domain-like
  • 55307 - Tubulin C-terminal domain-like
  • 0.01024Inherited
    49899,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 0.04032Inherited
    57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.0462Inherited
    47895,52540
  • 47895 - Transducin (alpha subunit), insertion domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.05259Inherited
    46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.07939Inherited
    47459,158457
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 158457 - Orange domain-like
  • 0.1469Inherited
    52799,52799
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0.1772Inherited
    47459,55785
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.1812Inherited
    57603,57603
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 0.1879Inherited
    47413,46689
  • 47413 - lambda repressor-like DNA-binding domains
  • 46689 - Homeodomain-like
  • 0.2421Inherited
    52058,57184
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.3008Inherited
    57184,52058
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.3008Inherited
    101912,103575
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 0.3618Inherited
    55785,55785
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.3769Inherited
    52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.3952Inherited
    57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 0.5004Inherited
    48726,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.5154Inherited
    103575,48726
  • 103575 - Plexin repeat
  • 48726 - Immunoglobulin
  • 0.6098Inherited
    57850,49599
  • 57850 - RING/U-box
  • 49599 - TRAF domain-like
  • 0.6098Inherited
    47954,47954
  • 47954 - Cyclin-like
  • 47954 - Cyclin-like
  • 0.7453Inherited
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.7453Inherited
    46689,46689
  • 46689 - Homeodomain-like
  • 46689 - Homeodomain-like
  • 0.941Inherited
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 1Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57196,57196,49899
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    49562,49562,53300
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 53300 - vWA-like
  • 0Direct
    57196,49899,49899
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    53300,81995,81811
  • 53300 - vWA-like
  • 81995 - beta-sandwich domain of Sec23/24
  • 81811 - Helical domain of Sec23/24
  • 0Direct
    53738,53738,53738
  • 53738 - Phosphoglucomutase, first 3 domains
  • 53738 - Phosphoglucomutase, first 3 domains
  • 53738 - Phosphoglucomutase, first 3 domains
  • 0Direct
    49899,57196,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0Direct
    52540,51045,51045
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51045 - WW domain
  • 51045 - WW domain
  • 0Direct
    49899,57196,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    54160,57850,57845
  • 54160 - Chromo domain-like
  • 57850 - RING/U-box
  • 57845 - B-box zinc-binding domain
  • 0Direct
    57440,57440,50494
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0Direct
    53738,53738,55957
  • 53738 - Phosphoglucomutase, first 3 domains
  • 53738 - Phosphoglucomutase, first 3 domains
  • 55957 - Phosphoglucomutase, C-terminal domain
  • 0Direct
    54160,52540,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    49562,48371,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    54160,54160,52540
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    52540,50447,50465
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
  • 0Direct
    48726,56436,56436
  • 48726 - Immunoglobulin
  • 56436 - C-type lectin-like
  • 56436 - C-type lectin-like
  • 0Direct
    57440,57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0Direct
    48065,103657,50044
  • 48065 - DBL homology domain (DH-domain)
  • 103657 - BAR/IMD domain-like
  • 50044 - SH3-domain
  • 0Direct
    103637,103637,103637
  • 103637 - CCHHC domain
  • 103637 - CCHHC domain
  • 103637 - CCHHC domain
  • 0Direct
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0Direct
    57196,49899,57196
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 0Direct
    103657,50729,48350
  • 103657 - BAR/IMD domain-like
  • 50729 - PH domain-like
  • 48350 - GTPase activation domain, GAP
  • 0Direct
    52058,52058,52058
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 0Direct
    46565,57938,49493
  • 46565 - Chaperone J-domain
  • 57938 - DnaJ/Hsp40 cysteine-rich domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 0Direct
    81995,81811,82754
  • 81995 - beta-sandwich domain of Sec23/24
  • 81811 - Helical domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0Direct
    50249,50249,50249
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 0Direct
    57424,57424,57184
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57184 - Growth factor receptor domain
  • 0Direct
    47220,47220,47220
  • 47220 - alpha-catenin/vinculin-like
  • 47220 - alpha-catenin/vinculin-like
  • 47220 - alpha-catenin/vinculin-like
  • 0Direct
    57184,57184,57196
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0Direct
    57424,57184,63825
  • 57424 - LDL receptor-like module
  • 57184 - Growth factor receptor domain
  • 63825 - YWTD domain
  • 0Direct
    57184,52058,57184
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0Direct
    54768,54768,54768
  • 54768 - dsRNA-binding domain-like
  • 54768 - dsRNA-binding domain-like
  • 54768 - dsRNA-binding domain-like
  • 0Direct
    63748,63748,63748
  • 63748 - Tudor/PWWP/MBT
  • 63748 - Tudor/PWWP/MBT
  • 63748 - Tudor/PWWP/MBT
  • 0Direct
    74788,75632,46785
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    54791,54791,54791
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 0Direct
    48592,54849,52029
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0Direct
    49854,57535,57535
  • 49854 - Spermadhesin, CUB domain
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0Direct
    49899,48726,49265
  • 49899 - Concanavalin A-like lectins/glucanases
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0Direct
    57535,49854,57535
  • 57535 - Complement control module/SCR domain
  • 49854 - Spermadhesin, CUB domain
  • 57535 - Complement control module/SCR domain
  • 0Direct
    57938,49493,49493
  • 57938 - DnaJ/Hsp40 cysteine-rich domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 0Direct
    48726,49265,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.1745Inherited
    46966,46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.22Inherited
    49899,49899,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 0.2391Inherited
    57603,57603,57603
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 0.3008Inherited
    48726,48726,49265
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.3097Inherited
    50044,55550,56112
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.3769Inherited
    52058,57184,52058
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.3792Inherited
    47459,55785,55785
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.4478Inherited
    49899,49899,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.6066Inherited
    101912,103575,48726
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 48726 - Immunoglobulin
  • 0.6098Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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