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Xenopus ANatomical entity (XAN): central nervous system

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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: XA Hierarchy (Xenopus anatomy and development from Xenbase frog anatomy ontology)

Shortest distance to current term (+ for parents, - for children) XA term [XA ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + 5:   Xenopus anatomical entity [XAO:0000000] <9>
+ + + + 4:   whole organism [XAO:0003004] <12>(448|575) (454|327|143)
+ + + + 4:   anatomical structure [XAO:0003000] <11>(574|728) (574|396|161)
+ + + 3:   anatomical group [XAO:0003001] <2>(372|480) (379|295|130)
+ + 2:   anatomical system [XAO:0003002] <19>(237|329) (246|189|86)
+ 1:   nervous system [XAO:0000177] <11>(136|202) (143|113|51)
0:   central nervous system [XAO:0000215] <7>(131|193) (136|108|47)
- 1:   neural nucleus [XAO:0004609] <34>(4|4) (4|1|0)
- 1:   eye [XAO:0000179] <16>(22|29) (25|14|6)
- 1:   brain [XAO:0000010] <15>(78|122) (81|64|28)
- 1:   spinal cord [XAO:0000020] <10>(18|24) (20|18|8)
- 1:   neural tube [XAO:0003204] <7>(10|14) (10|2|2)
- 1:   neuromere [XAO:0004597] <2>(3|3) (3|1|0)
- 1:   presumptive midbrain-hindbrain boundary [XAO:0004086](5|5) (5|2|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
TGS-like0Direct
Synuclein0Direct
DLC0Direct
MAST3 pre-PK domain-like0Direct
Phosphoglucomutase, first 3 domains0Direct
Cysteine-rich DNA binding domain, (DM domain)0Direct
A heparin-binding domain0Direct
ACP-like0Direct
HSP90 C-terminal domain0Direct
I/LWEQ domain0Direct
TK C-terminal domain-like0Direct
Hook domain0Direct
Notch domain0Direct
Alanine racemase C-terminal domain-like0Direct
Zn-finger domain of Sec23/240Direct
PAH2 domain0Direct
SPOC domain-like0Direct
Zn-binding ribosomal proteins0Direct
LuxS/MPP-like metallohydrolase0Direct
Ribulose-phoshate binding barrel0Direct
Thioesterase/thiol ester dehydrase-isomerase0Direct
Guanido kinase N-terminal domain0Direct
G protein-binding domain0Direct
Nuclear receptor coactivator interlocking domain0Direct
Nop domain0Direct
Succinyl-CoA synthetase domains0Direct
Subunits of heterodimeric actin filament capping protein Capz0Direct
BEACH domain0Direct
RNase III domain-like0Direct
Families 57/38 glycoside transferase middle domain0Direct
Glycoside hydrolase/deacetylase0Direct
USP8 N-terminal domain-like0Direct
Ligand-binding domain in the NO signalling and Golgi transport0Direct
Delta-sleep-inducing peptide immunoreactive peptide0Direct
Enolase C-terminal domain-like0Direct
AraD/HMP-PK domain-like0Direct
SRF-like0Direct
Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain0Direct
F1F0 ATP synthase subunit C0Direct
Cullin homology domain0Direct
Aconitase iron-sulfur domain0Direct
Isocitrate/Isopropylmalate dehydrogenase-like0Direct
Helical domain of Sec23/240Direct
SMAD MH1 domain0Direct
CCHHC domain0Direct
GroEL-intermediate domain like0Direct
GYF domain0Direct
Myosin phosphatase inhibitor 17kDa protein, CPI-170Direct
SWIB/MDM2 domain0Direct
Transcription factor STAT-4 N-domain0Direct
HSP40/DnaJ peptide-binding domain0Direct
ARID-like0Direct
eIF1-like0Direct
post-AAA+ oligomerization domain-like0Direct
DnaJ/Hsp40 cysteine-rich domain0Direct
Lamin A/C globular tail domain0Direct
Sec1/munc18-like (SM) proteins0Direct
Endosomal sorting complex assembly domain0Direct
Acyl-CoA binding protein0Direct
CAPPD, an extracellular domain of amyloid beta A4 protein0Direct
Cysteine alpha-hairpin motif0Direct
Moesin tail domain0Direct
NAP-like0Direct
Pentein0Direct
TAFH domain-like0Direct
Glutamine synthetase/guanido kinase0Direct
Bacterial exopeptidase dimerisation domain0Direct
4Fe-4S ferredoxins0Direct
Transducin (heterotrimeric G protein), gamma chain0Direct
Enolase N-terminal domain-like0Direct
Mib/herc2 domain-like0Direct
Aminomethyltransferase beta-barrel domain0Direct
Tim10-like0Direct
BRK domain-like0Direct
PLP-binding barrel0Direct
alpha-ketoacid dehydrogenase kinase, N-terminal domain0Direct
Stathmin0Direct
Clathrin adaptor appendage domain0Direct
LeuD/IlvD-like0Direct
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0Direct
Hedgehog/DD-peptidase0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Subdomain of clathrin and coatomer appendage domain0Direct
Amyloid beta a4 protein copper binding domain (domain 2)0Direct
14-3-3 protein0Direct
PriA/YqbF domain0Direct
Mss4-like0Direct
Phosphoglucomutase, C-terminal domain0Direct
Oligoxyloglucan reducing end-specific cellobiohydrolase0Direct
alpha-catenin/vinculin-like0Direct
GINS helical bundle-like0Direct
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0Direct
Thiamin diphosphate-binding fold (THDP-binding)0Direct
ThrRS/AlaRS common domain0Direct
Tubulin C-terminal domain-like0Direct
Dimeric alpha+beta barrel0Direct
TNF receptor-like0Direct
ClpS-like0Direct
beta-sandwich domain of Sec23/240Direct
RNA-binding domain, RBD0.0001544Direct
Ubiquitin-like0.0001891Direct
ARM repeat0.000561Direct
UBC-like0.0008085Direct
Cadherin-like0.0009503Direct
HMG-box0.001421Inherited
Frizzled cysteine-rich domain0.003504Inherited
Tubulin nucleotide-binding domain-like0.00492Inherited
PYP-like sensor domain (PAS domain)0.06349Inherited
Growth factor receptor domain0.06929Inherited
Orange domain-like0.1131Inherited
Cyclin-like0.2066Inherited
Sema domain0.2389Inherited
FnI-like domain0.4053Inherited
Plexin repeat0.4221Inherited
Fibronectin type III0.6307Inherited
TIMP-like0.6667Inherited
Kazal-type serine protease inhibitors0.6882Inherited
PH domain-like0.7918Inherited
Intermediate filament protein, coiled coil region0.8075Inherited
HLH, helix-loop-helix DNA-binding domain0.8362Inherited
Voltage-gated potassium channels0.9187Inherited
gamma-Crystallin-like0.9687Inherited
"Winged helix" DNA-binding domain0.9981Inherited
Family A G protein-coupled receptor-like1Inherited
EGF/Laminin1Inherited
lambda repressor-like DNA-binding domains1Inherited
Homeodomain-like1Inherited
POZ domain1Inherited
Cystine-knot cytokines1Inherited
Glucocorticoid receptor-like (DNA-binding domain)1Inherited
Cytokine1Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Moesin tail domain0Direct
A20-like zinc finger0Direct
Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta0Direct
a tRNA synthase domain0Direct
ZZ domain0Direct
Ferritin0Direct
HSP40/DnaJ peptide-binding domain0Direct
NAP-like0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Anticodon-binding domain of Class II aaRS0Direct
Group II chaperonin (CCT, TRIC), apical domain0Direct
I/LWEQ domain0Direct
Dimeric isocitrate & isopropylmalate dehydrogenases0Direct
Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A0Direct
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0Direct
Zn-finger domain of Sec23/240Direct
HCDH C-domain-like0Direct
CUE domain0Direct
Extracellular domain of cell surface receptors0Direct
Notch domain0Direct
CAPPD, an extracellular domain of amyloid beta A4 protein0Direct
Phosphoglucomutase, first 3 domains0Direct
Phosphoglucomutase, C-terminal domain0Direct
Branched-chain alpha-keto acid dehydrogenase Pyr module0Direct
PAH2 domain0Direct
Myosin phosphatase inhibitor 17kDa protein, CPI-170Direct
UDP-glucose pyrophosphorylase0Direct
P4 origin-binding domain-like0Direct
TAFH domain-like0Direct
Carboxylesterase/thioesterase 10Direct
beta-sandwich domain of Sec23/240Direct
SRF-like0Direct
SH3BGR (SH3-binding, glutamic acid-rich protein-like)0Direct
AraD-like aldolase/epimerase0Direct
Stathmin0Direct
Phoshoinositide 3-kinase (PI3K) helical domain0Direct
Heat shock protein 90, HSP90, N-terminal domain0Direct
DLC0Direct
Sec1/munc18-like (SM) proteins0Direct
TNF receptor-like0Direct
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain0Direct
PA domain0Direct
NTF2-like0Direct
Enolase N-terminal domain-like0Direct
alpha-mannosidase0Direct
Nuclear receptor coactivator interlocking domain0Direct
4HBT-like0Direct
Tubulin, C-terminal domain0Direct
HAT/Suf repeat0Direct
Glycosyl transferases group 10Direct
Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain0Direct
S-adenosylhomocystein hydrolase0Direct
Guanido kinase N-terminal domain0Direct
Hsp90 middle domain0Direct
Phoshatidylinositol transfer protein, PITP0Direct
Amyloid beta a4 protein copper binding domain (domain 2)0Direct
SMAD domain0Direct
Group II chaperonin (CCT, TRIC), intermediate domain0Direct
DIX domain0Direct
SCF ubiquitin ligase complex WHB domain0Direct
alpha-ketoacid dehydrogenase kinase, N-terminal domain0Direct
14-3-3 protein0Direct
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain0Direct
SMAD MH1 domain0Direct
Ubiquitin carboxyl-terminal hydrolase UCH-L0Direct
Cyclin A/CDK2-associated p19, Skp20Direct
GDI-like N domain0Direct
Alanine racemase-like, N-terminal domain0Direct
C-terminal, gelsolin-like domain of Sec23/240Direct
Eukaryotic ODC-like0Direct
B56-like0Direct
Transferrin0Direct
Arrestin/Vps26-like0Direct
Cullin homology domain0Direct
GS domain0Direct
ARID domain0Direct
HD domain0Direct
Transcription factor STAT-4 N-domain0Direct
LeuD-like0Direct
Linker histone H1/H50Direct
Delta-sleep-inducing peptide immunoreactive peptide0Direct
Guanido kinase catalytic domain0Direct
Branched-chain alpha-keto acid dehydrogenase PP module0Direct
Cell cycle control phosphatase, catalytic domain0Direct
Tim10/DDP0Direct
Acyl-CoA binding protein0Direct
Autophagin-like0Direct
RuBisCo LSMT catalytic domain0Direct
NIPSNAP0Direct
Cysteine-rich DNA binding domain, (DM domain)0Direct
alpha-catenin/vinculin0Direct
Glyoxalase II (hydroxyacylglutathione hydrolase)0Direct
alpha-mannosidase, C-terminal domain0Direct
TRAPP components0Direct
A heparin-binding domain0Direct
MSP-like0Direct
Hedgehog (development protein), N-terminal signaling domain0Direct
Bacterial exopeptidase dimerisation domain0Direct
Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain0Direct
DNA gyrase/MutL, second domain0Direct
Nop domain0Direct
Ran-binding domain0Direct
BRK domain-like0Direct
PAS domain of steroid receptor coactivator 1A, NCo-A10Direct
Clathrin adaptor appendage, alpha and beta chain-specific domain0Direct
Trunk domain of Sec23/240Direct
eIF1-like0Direct
Cytidylyltransferase0Direct
Gonadodropin/Follitropin0Direct
HSP90 C-terminal domain0Direct
gamma-adaptin C-terminal appendage domain-like0Direct
APC10-like0Direct
Variant RING domain0Direct
F1F0 ATP synthase subunit C0Direct
Aconitase iron-sulfur domain0Direct
Ephrin receptor ligand binding domain0Direct
Noggin0Direct
DnaJ/Hsp40 cysteine-rich domain0Direct
DJ-1/PfpI0Direct
Cofactor-dependent phosphoglycerate mutase0Direct
USP8 N-terminal domain-like0Direct
Chromo barrel domain0Direct
MAST3 pre-PK domain-like0Direct
DNA polymerase III clamp loader subunits, C-terminal domain0Direct
MPP-like0Direct
Mib/herc2 domain0Direct
Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain0Direct
SIAH, seven in absentia homolog0Direct
Adenain-like0Direct
SWIB/MDM2 domain0Direct
DNA gyrase/MutL, N-terminal domain0Direct
TRASH domain0Direct
Cullin repeat0Direct
BEACH domain0Direct
Sedlin (SEDL)0Direct
Lamin A/C globular tail domain0Direct
Cytochrome b50Direct
DNA ligase0Direct
Pumilio repeat0Direct
alpha-ketoacid dehydrogenase kinase, C-terminal domain0Direct
CCHHC domain0Direct
Threonyl-tRNA synthetase (ThrRS), second 'additional' domain0Direct
Succinyl-CoA synthetase domains0Direct
IF2B-like0Direct
Tubulin, GTPase domain0Direct
Phosphoribosylpyrophosphate synthetase-like0Direct
Transducin (heterotrimeric G protein), gamma chain0Direct
alpha-mannosidase, domain 20Direct
1,3-glucuronyltransferase0Direct
Neutral endopeptidase (neprilysin)0Direct
Aminomethyltransferase beta-barrel domain0Direct
Helical domain of Sec23/240Direct
PreBEACH PH-like domain0Direct
Other IPT/TIG domains0Direct
Hook domain0Direct
Alpha-adaptin ear subdomain-like0Direct
Synuclein0Direct
RPR domain (SMART 00582 )0Direct
Protein-L-isoaspartyl O-methyltransferase0Direct
Canonical RBD0.00003031Direct
UBC-related0.00007274Direct
Third domain of FERM0.0004137Direct
HMG-box0.001419Inherited
Frizzled cysteine-rich domain0.003185Inherited
Laminin G-like module0.01034Inherited
Histone lysine methyltransferases0.01191Inherited
Growth factor receptor domain0.03523Inherited
ets domain0.05633Inherited
Hairy Orange domain0.1036Inherited
Sema domain0.1897Inherited
VWC domain0.2344Inherited
L domain0.2408Inherited
Tandem AAA-ATPase domain0.2603Inherited
Higher-molecular-weight phosphotyrosine protein phosphatases0.2689Inherited
Cyclin0.345Inherited
Tetramerization domain of potassium channels0.3981Inherited
Plexin repeat0.419Inherited
Ovomucoid domain III-like0.5017Inherited
Fibronectin type III0.5924Inherited
Intermediate filament protein, coiled coil region0.8033Inherited
HLH, helix-loop-helix DNA-binding domain0.8169Inherited
Erythroid transcription factor GATA-10.8362Inherited
I set domains0.9185Inherited
Crystallins/Ca-binding development proteins0.9532Inherited
Voltage-gated potassium channels0.9667Inherited
Paired domain1Inherited
Homeodomain1Inherited
Forkhead DNA-binding domain1Inherited
Fibroblast growth factors (FGF)1Inherited
POU-specific domain1Inherited
Rhodopsin-like1Inherited
Classic zinc finger, C2H21Inherited
LIM domain1Inherited


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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Aconitase iron-sulfur domain0Direct
Nop domain0Direct
A heparin-binding domain0Direct
ARID-like0Direct
TK C-terminal domain-like0Direct
Phosphoglucomutase, C-terminal domain0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Ribulose-phoshate binding barrel0Direct
SPOC domain-like0Direct
Zn-binding ribosomal proteins0Direct
Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain0Direct
Myosin phosphatase inhibitor 17kDa protein, CPI-170Direct
DLC0Direct
GINS helical bundle-like0Direct
PLP-binding barrel0Direct
GroEL-intermediate domain like0Direct
beta-sandwich domain of Sec23/240Direct
PriA/YqbF domain0Direct
Amyloid beta a4 protein copper binding domain (domain 2)0Direct
RNase III domain-like0Direct
Guanido kinase N-terminal domain0Direct
Tubulin C-terminal domain-like0Direct
Lamin A/C globular tail domain0Direct
Succinyl-CoA synthetase domains0Direct
Sec1/munc18-like (SM) proteins0Direct
4Fe-4S ferredoxins0Direct
BEACH domain0Direct
HSP40/DnaJ peptide-binding domain0Direct
ThrRS/AlaRS common domain0Direct
TGS-like0Direct
SRF-like0Direct
Glycoside hydrolase/deacetylase0Direct
Helical domain of Sec23/240Direct
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0Direct
Subunits of heterodimeric actin filament capping protein Capz0Direct
Phosphoglucomutase, first 3 domains0Direct
Nuclear receptor coactivator interlocking domain0Direct
Cysteine alpha-hairpin motif0Direct
BRK domain-like0Direct
post-AAA+ oligomerization domain-like0Direct
CAPPD, an extracellular domain of amyloid beta A4 protein0Direct
SWIB/MDM2 domain0Direct
Thioesterase/thiol ester dehydrase-isomerase0Direct
Zn-finger domain of Sec23/240Direct
Subdomain of clathrin and coatomer appendage domain0Direct
Pentein0Direct
Endosomal sorting complex assembly domain0Direct
Delta-sleep-inducing peptide immunoreactive peptide0Direct
Acyl-CoA binding protein0Direct
LeuD/IlvD-like0Direct
Moesin tail domain0Direct
Synuclein0Direct
USP8 N-terminal domain-like0Direct
Aminomethyltransferase beta-barrel domain0Direct
Hedgehog/DD-peptidase0Direct
Clathrin adaptor appendage domain0Direct
G protein-binding domain0Direct
TAFH domain-like0Direct
I/LWEQ domain0Direct
HSP90 C-terminal domain0Direct
F1F0 ATP synthase subunit C0Direct
Bacterial exopeptidase dimerisation domain0Direct
Alanine racemase C-terminal domain-like0Direct
Ligand-binding domain in the NO signalling and Golgi transport0Direct
Isocitrate/Isopropylmalate dehydrogenase-like0Direct
alpha-catenin/vinculin-like0Direct
Enolase C-terminal domain-like0Direct
14-3-3 protein0Direct
Transcription factor STAT-4 N-domain0Direct
Thiamin diphosphate-binding fold (THDP-binding)0Direct
TNF receptor-like0Direct
AraD/HMP-PK domain-like0Direct
Hook domain0Direct
DnaJ/Hsp40 cysteine-rich domain0Direct
Stathmin0Direct
NAP-like0Direct
Mib/herc2 domain-like0Direct
PAH2 domain0Direct
Oligoxyloglucan reducing end-specific cellobiohydrolase0Direct
ClpS-like0Direct
Transducin (heterotrimeric G protein), gamma chain0Direct
eIF1-like0Direct
Families 57/38 glycoside transferase middle domain0Direct
SMAD MH1 domain0Direct
CCHHC domain0Direct
ACP-like0Direct
Glutamine synthetase/guanido kinase0Direct
alpha-ketoacid dehydrogenase kinase, N-terminal domain0Direct
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0Direct
Enolase N-terminal domain-like0Direct
Tim10-like0Direct
Cysteine-rich DNA binding domain, (DM domain)0Direct
Dimeric alpha+beta barrel0Direct
Notch domain0Direct
Cullin homology domain0Direct
Mss4-like0Direct
LuxS/MPP-like metallohydrolase0Direct
MAST3 pre-PK domain-like0Direct
GYF domain0Direct
RNA-binding domain, RBD0.0001138Direct
Ubiquitin-like0.0001398Direct
ARM repeat0.0004205Direct
UBC-like0.0006091Direct
Cadherin-like0.0007169Direct
HMG-box0.00108Inherited
Frizzled cysteine-rich domain0.002693Inherited
Tubulin nucleotide-binding domain-like0.003798Inherited
PYP-like sensor domain (PAS domain)0.05243Inherited
Growth factor receptor domain0.05745Inherited
Orange domain-like0.09668Inherited
SET domain0.1561Inherited
Cyclin-like0.1831Inherited
Sema domain0.2135Inherited
Galactose-binding domain-like0.3189Inherited
FnI-like domain0.3736Inherited
Plexin repeat0.389Inherited
P-domain of calnexin/calreticulin0.3996Inherited
Fibronectin type III0.595Inherited
TIMP-like0.6312Inherited
Kazal-type serine protease inhibitors0.6522Inherited
PH domain-like0.7588Inherited
Intermediate filament protein, coiled coil region0.7757Inherited
HLH, helix-loop-helix DNA-binding domain0.8058Inherited
Voltage-gated potassium channels0.8906Inherited
gamma-Crystallin-like0.9428Inherited
"Winged helix" DNA-binding domain0.9743Inherited
p53-like transcription factors0.9948Inherited
Cytokine1Inherited
Cystine-knot cytokines1Inherited
EGF/Laminin1Inherited
Immunoglobulin1Inherited
Homeodomain-like1Inherited
Family A G protein-coupled receptor-like1Inherited
Glucocorticoid receptor-like (DNA-binding domain)1Inherited
lambda repressor-like DNA-binding domains1Inherited
POZ domain1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
74788,75632
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 0Direct
    54160,54160
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 0Direct
    51045,50156
  • 51045 - WW domain
  • 50156 - PDZ domain-like
  • 0Direct
    49493,49493
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 0Direct
    50447,50465
  • 50447 - Translation proteins
  • 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
  • 0Direct
    81324,53850
  • 81324 - Voltage-gated potassium channels
  • 53850 - Periplasmic binding protein-like II
  • 0Direct
    50729,57889
  • 50729 - PH domain-like
  • 57889 - Cysteine-rich domain
  • 0Direct
    52540,47917
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase
  • 0Direct
    50729,81837
  • 50729 - PH domain-like
  • 81837 - BEACH domain
  • 0Direct
    47370,47370
  • 47370 - Bromodomain
  • 47370 - Bromodomain
  • 0Direct
    54637,54637
  • 54637 - Thioesterase/thiol ester dehydrase-isomerase
  • 54637 - Thioesterase/thiol ester dehydrase-isomerase
  • 0Direct
    49899,48726
  • 49899 - Concanavalin A-like lectins/glucanases
  • 48726 - Immunoglobulin
  • 0Direct
    53738,53738
  • 53738 - Phosphoglucomutase, first 3 domains
  • 53738 - Phosphoglucomutase, first 3 domains
  • 0Direct
    57424,57184
  • 57424 - LDL receptor-like module
  • 57184 - Growth factor receptor domain
  • 0Direct
    54631,54631
  • 54631 - CBS-domain pair
  • 54631 - CBS-domain pair
  • 0Direct
    51419,50621
  • 51419 - PLP-binding barrel
  • 50621 - Alanine racemase C-terminal domain-like
  • 0Direct
    75632,46785
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    57184,49265
  • 57184 - Growth factor receptor domain
  • 49265 - Fibronectin type III
  • 0Direct
    57863,48403
  • 57863 - ArfGap/RecO-like zinc finger
  • 48403 - Ankyrin repeat
  • 0Direct
    56491,89811
  • 56491 - A heparin-binding domain
  • 89811 - Amyloid beta a4 protein copper binding domain (domain 2)
  • 0Direct
    52490,55307
  • 52490 - Tubulin nucleotide-binding domain-like
  • 55307 - Tubulin C-terminal domain-like
  • 0Direct
    57938,49493
  • 57938 - DnaJ/Hsp40 cysteine-rich domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 0Direct
    52518,52518
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 0Direct
    55874,54211
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0Direct
    52821,52799
  • 52821 - Rhodanese/Cell cycle control phosphatase
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    47473,57889
  • 47473 - EF-hand
  • 57889 - Cysteine-rich domain
  • 0Direct
    56436,57535
  • 56436 - C-type lectin-like
  • 57535 - Complement control module/SCR domain
  • 0Direct
    53300,81995
  • 53300 - vWA-like
  • 81995 - beta-sandwich domain of Sec23/24
  • 0Direct
    57196,100895
  • 57196 - EGF/Laminin
  • 100895 - Kazal-type serine protease inhibitors
  • 0Direct
    57889,50729
  • 57889 - Cysteine-rich domain
  • 50729 - PH domain-like
  • 0Direct
    63411,63411
  • 63411 - LuxS/MPP-like metallohydrolase
  • 63411 - LuxS/MPP-like metallohydrolase
  • 0Direct
    50998,50978
  • 50998 - Quinoprotein alcohol dehydrogenase-like
  • 50978 - WD40 repeat-like
  • 0Direct
    50044,50156
  • 50044 - SH3-domain
  • 50156 - PDZ domain-like
  • 0Direct
    53732,52016
  • 53732 - Aconitase iron-sulfur domain
  • 52016 - LeuD/IlvD-like
  • 0Direct
    54452,48726
  • 54452 - MHC antigen-recognition domain
  • 48726 - Immunoglobulin
  • 0Direct
    46565,57938
  • 46565 - Chaperone J-domain
  • 57938 - DnaJ/Hsp40 cysteine-rich domain
  • 0Direct
    103637,103637
  • 103637 - CCHHC domain
  • 103637 - CCHHC domain
  • 0Direct
    48371,46785
  • 48371 - ARM repeat
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    57196,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0Direct
    49562,48371
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 0Direct
    57903,51197
  • 57903 - FYVE/PHD zinc finger
  • 51197 - Clavaminate synthase-like
  • 0Direct
    53850,53850
  • 53850 - Periplasmic binding protein-like II
  • 53850 - Periplasmic binding protein-like II
  • 0Direct
    100895,47473
  • 100895 - Kazal-type serine protease inhibitors
  • 47473 - EF-hand
  • 0Direct
    54160,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    52540,46785
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    54160,57850
  • 54160 - Chromo domain-like
  • 57850 - RING/U-box
  • 0Direct
    117281,50965
  • 117281 - Kelch motif
  • 50965 - Galactose oxidase, central domain
  • 0Direct
    88713,88688
  • 88713 - Glycoside hydrolase/deacetylase
  • 88688 - Families 57/38 glycoside transferase middle domain
  • 0Direct
    48065,103657
  • 48065 - DBL homology domain (DH-domain)
  • 103657 - BAR/IMD domain-like
  • 0Direct
    56059,52210
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 52210 - Succinyl-CoA synthetase domains
  • 0Direct
    57535,49854
  • 57535 - Complement control module/SCR domain
  • 49854 - Spermadhesin, CUB domain
  • 0Direct
    48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 0Direct
    47095,47095
  • 47095 - HMG-box
  • 47095 - HMG-box
  • 0Direct
    81995,81811
  • 81995 - beta-sandwich domain of Sec23/24
  • 81811 - Helical domain of Sec23/24
  • 0Direct
    57196,49899
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    52540,48019
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 48019 - post-AAA+ oligomerization domain-like
  • 0Direct
    57440,50494
  • 57440 - Kringle-like
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    82919,53300
  • 82919 - Zn-finger domain of Sec23/24
  • 53300 - vWA-like
  • 0Direct
    48350,50729
  • 48350 - GTPase activation domain, GAP
  • 50729 - PH domain-like
  • 0Direct
    56112,48371
  • 56112 - Protein kinase-like (PK-like)
  • 48371 - ARM repeat
  • 0Direct
    81271,55186
  • 81271 - TGS-like
  • 55186 - ThrRS/AlaRS common domain
  • 0Direct
    47220,47220
  • 47220 - alpha-catenin/vinculin-like
  • 47220 - alpha-catenin/vinculin-like
  • 0Direct
    69012,55874
  • 69012 - alpha-ketoacid dehydrogenase kinase, N-terminal domain
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 0Direct
    81811,82754
  • 81811 - Helical domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0Direct
    53223,51735
  • 53223 - Aminoacid dehydrogenase-like, N-terminal domain
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0Direct
    64593,74853
  • 64593 - Intermediate filament protein, coiled coil region
  • 74853 - Lamin A/C globular tail domain
  • 0Direct
    63501,50242
  • 63501 - Frizzled cysteine-rich domain
  • 50242 - TIMP-like
  • 0Direct
    56112,47769
  • 56112 - Protein kinase-like (PK-like)
  • 47769 - SAM/Pointed domain
  • 0Direct
    52540,51045
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51045 - WW domain
  • 0Direct
    48726,56436
  • 48726 - Immunoglobulin
  • 56436 - C-type lectin-like
  • 0Direct
    57903,47370
  • 57903 - FYVE/PHD zinc finger
  • 47370 - Bromodomain
  • 0Direct
    49562,53300
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 53300 - vWA-like
  • 0Direct
    53187,55031
  • 53187 - Zn-dependent exopeptidases
  • 55031 - Bacterial exopeptidase dimerisation domain
  • 0Direct
    48403,50044
  • 48403 - Ankyrin repeat
  • 50044 - SH3-domain
  • 0Direct
    52518,52922
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 52922 - TK C-terminal domain-like
  • 0Direct
    57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0Direct
    69065,54768
  • 69065 - RNase III domain-like
  • 54768 - dsRNA-binding domain-like
  • 0Direct
    57184,100895
  • 57184 - Growth factor receptor domain
  • 100895 - Kazal-type serine protease inhibitors
  • 0Direct
    47473,57850
  • 47473 - EF-hand
  • 57850 - RING/U-box
  • 0Direct
    48592,54849
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 0Direct
    47473,103506
  • 47473 - EF-hand
  • 103506 - Mitochondrial carrier
  • 0Direct
    57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0Direct
    53738,55957
  • 53738 - Phosphoglucomutase, first 3 domains
  • 55957 - Phosphoglucomutase, C-terminal domain
  • 0Direct
    52540,53254
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 53254 - Phosphoglycerate mutase-like
  • 0Direct
    49348,55711
  • 49348 - Clathrin adaptor appendage domain
  • 55711 - Subdomain of clathrin and coatomer appendage domain
  • 0Direct
    57184,49899
  • 57184 - Growth factor receptor domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    103025,101790
  • 103025 - Folate-binding domain
  • 101790 - Aminomethyltransferase beta-barrel domain
  • 0Direct
    48034,55931
  • 48034 - Guanido kinase N-terminal domain
  • 55931 - Glutamine synthetase/guanido kinase
  • 0Direct
    54849,52029
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0Direct
    49899,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 0.02019Inherited
    47459,158457
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 158457 - Orange domain-like
  • 0.09668Inherited
    47459,55785
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.1088Inherited
    57603,57603
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 0.1306Inherited
    52799,52799
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0.1759Inherited
    101912,103575
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 0.2135Inherited
    52058,57184
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.2322Inherited
    57184,52058
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.2322Inherited
    55785,55785
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.2754Inherited
    49899,63887
  • 49899 - Concanavalin A-like lectins/glucanases
  • 63887 - P-domain of calnexin/calreticulin
  • 0.3996Inherited
    103575,48726
  • 103575 - Plexin repeat
  • 48726 - Immunoglobulin
  • 0.5048Inherited
    48726,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.506Inherited
    47954,47954
  • 47954 - Cyclin-like
  • 47954 - Cyclin-like
  • 0.5605Inherited
    49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.5928Inherited
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.6895Inherited
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 1Inherited
    57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 1Inherited
    47413,46689
  • 47413 - lambda repressor-like DNA-binding domains
  • 46689 - Homeodomain-like
  • 1Inherited
    50729,50729
  • 50729 - PH domain-like
  • 50729 - PH domain-like
  • 1Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57196,57196,49899
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    103657,50729,48350
  • 103657 - BAR/IMD domain-like
  • 50729 - PH domain-like
  • 48350 - GTPase activation domain, GAP
  • 0Direct
    74788,75632,46785
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    81995,81811,82754
  • 81995 - beta-sandwich domain of Sec23/24
  • 81811 - Helical domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0Direct
    57440,57440,50494
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    46565,57938,49493
  • 46565 - Chaperone J-domain
  • 57938 - DnaJ/Hsp40 cysteine-rich domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 0Direct
    52540,51045,51045
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51045 - WW domain
  • 51045 - WW domain
  • 0Direct
    57424,57184,63825
  • 57424 - LDL receptor-like module
  • 57184 - Growth factor receptor domain
  • 63825 - YWTD domain
  • 0Direct
    52540,50447,50465
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
  • 0Direct
    48065,103657,50044
  • 48065 - DBL homology domain (DH-domain)
  • 103657 - BAR/IMD domain-like
  • 50044 - SH3-domain
  • 0Direct
    49562,48371,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    49899,57196,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    53738,53738,53738
  • 53738 - Phosphoglucomutase, first 3 domains
  • 53738 - Phosphoglucomutase, first 3 domains
  • 53738 - Phosphoglucomutase, first 3 domains
  • 0Direct
    57440,57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0Direct
    53738,53738,55957
  • 53738 - Phosphoglucomutase, first 3 domains
  • 53738 - Phosphoglucomutase, first 3 domains
  • 55957 - Phosphoglucomutase, C-terminal domain
  • 0Direct
    50249,50249,50249
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 0Direct
    54768,54768,54768
  • 54768 - dsRNA-binding domain-like
  • 54768 - dsRNA-binding domain-like
  • 54768 - dsRNA-binding domain-like
  • 0Direct
    54791,54791,54791
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 0Direct
    49854,57535,57535
  • 49854 - Spermadhesin, CUB domain
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0Direct
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0Direct
    57424,57424,57184
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57184 - Growth factor receptor domain
  • 0Direct
    48726,56436,56436
  • 48726 - Immunoglobulin
  • 56436 - C-type lectin-like
  • 56436 - C-type lectin-like
  • 0Direct
    54160,52540,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    49899,57196,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0Direct
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0Direct
    57196,49899,57196
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 0Direct
    48592,54849,52029
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0Direct
    57184,57184,57196
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0Direct
    47220,47220,47220
  • 47220 - alpha-catenin/vinculin-like
  • 47220 - alpha-catenin/vinculin-like
  • 47220 - alpha-catenin/vinculin-like
  • 0Direct
    52058,52058,52058
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 0Direct
    54160,57850,57845
  • 54160 - Chromo domain-like
  • 57850 - RING/U-box
  • 57845 - B-box zinc-binding domain
  • 0Direct
    49562,49562,53300
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 53300 - vWA-like
  • 0Direct
    57184,52058,57184
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0Direct
    103637,103637,103637
  • 103637 - CCHHC domain
  • 103637 - CCHHC domain
  • 103637 - CCHHC domain
  • 0Direct
    49899,48726,49265
  • 49899 - Concanavalin A-like lectins/glucanases
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0Direct
    54160,54160,52540
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    53300,81995,81811
  • 53300 - vWA-like
  • 81995 - beta-sandwich domain of Sec23/24
  • 81811 - Helical domain of Sec23/24
  • 0Direct
    57535,49854,57535
  • 57535 - Complement control module/SCR domain
  • 49854 - Spermadhesin, CUB domain
  • 57535 - Complement control module/SCR domain
  • 0Direct
    57938,49493,49493
  • 57938 - DnaJ/Hsp40 cysteine-rich domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 0Direct
    57196,49899,49899
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    48371,48371,48371
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 0.1306Inherited
    48726,48726,49265
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.1982Inherited
    57603,57603,57603
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 0.2322Inherited
    50044,55550,56112
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.2754Inherited
    52058,57184,52058
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.3055Inherited
    47459,55785,55785
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.3402Inherited
    101912,103575,48726
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 48726 - Immunoglobulin
  • 0.5048Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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