SUPERFAMILY 1.75 HMM library and genome assignments server

Superfamily is undergoing a server migration - you are now browsing on the new server. Please contact us if you experience any problems.

Xenopus ANatomical entity (XAN): trunk

(show info)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: XA Hierarchy (Xenopus anatomy and development from Xenbase frog anatomy ontology)

Shortest distance to current term (+ for parents, - for children) XA term [XA ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   anatomical structure [XAO:0003000] <11>(574|728) (574|396|161)
+ + + 3:   whole organism [XAO:0003004] <12>(448|575) (454|327|143)
+ + + 3:   Xenopus anatomical entity [XAO:0000000] <9>
+ + 2:   multicellular anatomical structure [XAO:0005002] <4>(435|562) (438|323|141)
+ + 2:   anatomical region [XAO:0003186] <43>(371|485) (375|286|122)
+ 1:   organism subdivision [XAO:0003013] <11>(375|497) (382|292|125)
+ 1:   trunk region [XAO:0000054] <1>(215|301) (217|157|81)
0:   trunk [XAO:0003025] <10>(214|300) (216|157|81)
- 1:   trunk vasculature [XAO:0004423] <30>(3|4) (3|1|0)
- 1:   trunk somite [XAO:0000314] <13>(1|2) (1|1|1)
- 1:   viscus [XAO:0003034] <9>(64|97) (67|45|21)
- 1:   gonad [XAO:0003146] <2>(84|128) (84|69|34)
- 1:   mesonephric kidney [XAO:0000141] <2>(2|1) (2|0|0)
- 1:   trunk musculature [XAO:0003230] <2>(3|5) (3|2|1)
- 1:   coelom [XAO:0004521] <1>(12|16) (12|5|4)
- 1:   dorsal trunk [XAO:0005265](0|0) (0|0|0)
- 1:   mesonephric mesenchyme [XAO:0000291](0|0) (0|0|0)
- 1:   ventral trunk [XAO:0005260](0|0) (0|0|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
LDH C-terminal domain-like0Direct
KA1-like0Direct
TGS-like0Direct
Phosphoglucomutase, first 3 domains0Direct
occludin/ELL-like0Direct
Transducin (alpha subunit), insertion domain0Direct
Cation efflux protein cytoplasmic domain-like0Direct
PEBP-like0Direct
VHP, Villin headpiece domain0Direct
ACP-like0Direct
Formate/glycerate dehydrogenase catalytic domain-like0Direct
MHC antigen-recognition domain0Direct
Lipovitellin-phosvitin complex; beta-sheet shell regions0Direct
HSP90 C-terminal domain0Direct
2Fe-2S ferredoxin-like0Direct
PA domain0Direct
Supernatant protein factor (SPF), C-terminal domain0Direct
Chitinase insertion domain0Direct
MIR domain0Direct
FtsH protease domain-like0Direct
Elongation factor TFIIS domain 20Direct
TK C-terminal domain-like0Direct
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex0Direct
Ribonuclease PH domain 2-like0Direct
FMN-linked oxidoreductases0Direct
FabD/lysophospholipase-like0Direct
Notch domain0Direct
Sec63 N-terminal domain-like0Direct
Alanine racemase C-terminal domain-like0Direct
GAT-like domain0Direct
Insulin-like0Direct
Fibrinogen coiled-coil and central regions0Direct
Lipovitellin-phosvitin complex, superhelical domain0Direct
Zn-finger domain of Sec23/240Direct
PAH2 domain0Direct
TSP type-3 repeat0Direct
BAG domain0Direct
SPOC domain-like0Direct
ADP-ribosylglycohydrolase0Direct
Thioesterase/thiol ester dehydrase-isomerase0Direct
Guanido kinase N-terminal domain0Direct
Homocysteine S-methyltransferase0Direct
G protein-binding domain0Direct
Nuclear receptor coactivator interlocking domain0Direct
FMT C-terminal domain-like0Direct
DHS-like NAD/FAD-binding domain0Direct
Nop domain0Direct
Succinyl-CoA synthetase domains0Direct
Subunits of heterodimeric actin filament capping protein Capz0Direct
RNase III domain-like0Direct
Families 57/38 glycoside transferase middle domain0Direct
Invertebrate chitin-binding proteins0Direct
Smc hinge domain0Direct
Zinc beta-ribbon0Direct
Cu,Zn superoxide dismutase-like0Direct
Cullin repeat-like0Direct
Eferin C-derminal domain-like0Direct
FAD-binding/transporter-associated domain-like0Direct
USP8 N-terminal domain-like0Direct
Ligand-binding domain in the NO signalling and Golgi transport0Direct
Delta-sleep-inducing peptide immunoreactive peptide0Direct
C-terminal domain of adenylylcyclase associated protein0Direct
HRDC-like0Direct
THUMP domain-like0Direct
IP3 receptor type 1 binding core, domain 20Direct
Surp module (SWAP domain)0Direct
Enolase C-terminal domain-like0Direct
AraD/HMP-PK domain-like0Direct
SRF-like0Direct
Ammonium transporter0Direct
Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain0Direct
Nucleoporin domain0Direct
Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain0Direct
F1F0 ATP synthase subunit C0Direct
Cullin homology domain0Direct
L27 domain0Direct
Restriction endonuclease-like0Direct
Glycolipid transfer protein, GLTP0Direct
Cryptochrome/photolyase, N-terminal domain0Direct
Aconitase iron-sulfur domain0Direct
HR1 repeat0Direct
Amidase signature (AS) enzymes0Direct
ValRS/IleRS/LeuRS editing domain0Direct
Apolipoprotein A-I0Direct
Isocitrate/Isopropylmalate dehydrogenase-like0Direct
Nucleoside diphosphate kinase, NDK0Direct
PapD-like0Direct
EF-G C-terminal domain-like0Direct
Mannose 6-phosphate receptor domain0Direct
Tricorn protease domain 20Direct
Helical domain of Sec23/240Direct
SMAD MH1 domain0Direct
Adenine nucleotide alpha hydrolases-like0Direct
Cryptochrome/photolyase FAD-binding domain0Direct
PAZ domain0Direct
GYF domain0Direct
S15/NS1 RNA-binding domain0Direct
Myosin phosphatase inhibitor 17kDa protein, CPI-170Direct
SAP domain0Direct
SIS domain0Direct
Creatinase/aminopeptidase0Direct
FAD-linked oxidoreductase0Direct
Cap-Gly domain0Direct
RmlC-like cupins0Direct
MAPEG domain-like0Direct
DNA repair protein MutS, domain III0Direct
Carbon-nitrogen hydrolase0Direct
eIF1-like0Direct
Proteasome activator0Direct
FF domain0Direct
post-AAA+ oligomerization domain-like0Direct
DnaJ/Hsp40 cysteine-rich domain0Direct
6-phosphogluconate dehydrogenase C-terminal domain-like0Direct
DNA clamp0Direct
Nucleotide cyclase0Direct
Sec1/munc18-like (SM) proteins0Direct
Endosomal sorting complex assembly domain0Direct
DNA polymerase beta, N-terminal domain-like0Direct
Moesin tail domain0Direct
NAP-like0Direct
MIT domain0Direct
Oxysterol-binding protein-like0Direct
C-terminal, gelsolin-like domain of Sec23/240Direct
PABC (PABP) domain0Direct
WGR domain-like0Direct
Alpha-macroglobulin receptor domain0Direct
N-acetylmuramoyl-L-alanine amidase-like0Direct
Glutamine synthetase/guanido kinase0Direct
TB module/8-cys domain0Direct
4Fe-4S ferredoxins0Direct
Ribosomal proteins S24e, L23 and L15e0Direct
CoA-dependent acyltransferases0Direct
UBC-like0Direct
Enolase N-terminal domain-like0Direct
L-aspartase-like0Direct
Mib/herc2 domain-like0Direct
Creatinase/prolidase N-terminal domain0Direct
Heat shock protein 70kD (HSP70), C-terminal subdomain0Direct
Aminomethyltransferase beta-barrel domain0Direct
Heat shock protein 70kD (HSP70), peptide-binding domain0Direct
Tim10-like0Direct
BRK domain-like0Direct
PLP-binding barrel0Direct
The spindle assembly checkpoint protein mad20Direct
DUSP-like0Direct
JAB1/MPN domain0Direct
Galactose mutarotase-like0Direct
alpha-ketoacid dehydrogenase kinase, N-terminal domain0Direct
Band 7/SPFH domain0Direct
Cytidine deaminase-like0Direct
Clathrin adaptor appendage domain0Direct
LeuD/IlvD-like0Direct
Hedgehog/DD-peptidase0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
NTF2-like0Direct
Subdomain of clathrin and coatomer appendage domain0Direct
E2F-DP heterodimerization region0Direct
Phosphoglucomutase, C-terminal domain0Direct
BSD domain-like0Direct
Oligoxyloglucan reducing end-specific cellobiohydrolase0Direct
Domain of poly(ADP-ribose) polymerase0Direct
Activating enzymes of the ubiquitin-like proteins0Direct
alpha-catenin/vinculin-like0Direct
Inosine monophosphate dehydrogenase (IMPDH)0Direct
NagB/RpiA/CoA transferase-like0Direct
RCC1/BLIP-II0Direct
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0Direct
Thiamin diphosphate-binding fold (THDP-binding)0Direct
ThrRS/AlaRS common domain0Direct
GFP-like0Direct
TNF receptor-like0Direct
Thiolase-like0Direct
ClpS-like0Direct
SCP-like0Direct
beta-sandwich domain of Sec23/240Direct
ARM repeat0.00003188Direct
WD40 repeat-like0.0002173Direct
Ribonuclease H-like0.0004559Direct
NAD(P)-binding Rossmann-fold domains0.001072Inherited
Tudor/PWWP/MBT0.003084Inherited
Actin-like ATPase domain0.003822Inherited
P-loop containing nucleoside triphosphate hydrolases0.005763Inherited
RNA-binding domain, RBD0.007206Inherited
Translation proteins0.06202Inherited
PYP-like sensor domain (PAS domain)0.07154Inherited
FYVE/PHD zinc finger0.1524Inherited
SMAD/FHA domain0.1736Inherited
Tropomyosin0.1838Inherited
PLP-dependent transferases0.2038Inherited
Leukotriene A4 hydrolase N-terminal domain0.2173Inherited
ALDH-like0.2237Inherited
Growth factor receptor domain0.2252Inherited
"Winged helix" DNA-binding domain0.2396Inherited
Orange domain-like0.2604Inherited
Clavaminate synthase-like0.2903Inherited
ARID-like0.3105Inherited
Translation proteins SH3-like domain0.3105Inherited
Thioredoxin-like0.4226Inherited
Translational machinery components0.4343Inherited
Zn-binding ribosomal proteins0.5107Inherited
Trypsin-like serine proteases0.5351Inherited
HMG-box0.5597Inherited
EGF/Laminin0.6592Inherited
SAM/Pointed domain0.7469Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.7732Inherited
Snake toxin-like0.8267Inherited
EF-hand0.9178Inherited
Troponin coil-coiled subunits0.9481Inherited
Frizzled cysteine-rich domain1Inherited
lambda repressor-like DNA-binding domains1Inherited
Homeodomain-like1Inherited
Cystine-knot cytokines1Inherited
p53-like transcription factors1Inherited
HLH, helix-loop-helix DNA-binding domain1Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
ValRS/IleRS/LeuRS editing domain0Direct
Cation efflux protein transmembrane domain-like0Direct
Transcriptional factor domain0Direct
Moesin tail domain0Direct
Cystathionine synthase-like0Direct
ELL N2 domain-like0Direct
A20-like zinc finger0Direct
Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta0Direct
a tRNA synthase domain0Direct
Regulator of chromosome condensation RCC10Direct
Ferredoxin reductase FAD-binding domain-like0Direct
ZZ domain0Direct
Ferritin0Direct
Malic enzyme N-domain0Direct
Steroid-binding domain0Direct
Domain of poly(ADP-ribose) polymerase0Direct
Sterol carrier protein, SCP0Direct
GAT domain0Direct
NAP-like0Direct
Thiolase-related0Direct
Nucleoside diphosphate kinase, NDK0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Anticodon-binding domain of Class II aaRS0Direct
Translational machinery components0Direct
Neurolysin-like0Direct
CAD domain0Direct
Dimeric isocitrate & isopropylmalate dehydrogenases0Direct
CAT-like0Direct
Elongation factors0Direct
Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A0Direct
DUSP, domain in ubiquitin-specific proteases0Direct
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0Direct
Hypoxia-inducible factor HIF ihhibitor (FIH1)0Direct
Zn-finger domain of Sec23/240Direct
Occludin/ELL domain0Direct
HCDH C-domain-like0Direct
CUE domain0Direct
Formate/glycerate dehydrogenases, substrate-binding domain0Direct
PABC (PABP) domain0Direct
Notch domain0Direct
Elongation factor TFIIS domain 20Direct
Phosphoglucomutase, first 3 domains0Direct
Deoxycytidylate deaminase-like0Direct
Phosphoglucomutase, C-terminal domain0Direct
Branched-chain alpha-keto acid dehydrogenase Pyr module0Direct
PAH2 domain0Direct
Noncollagenous (NC1) domain of collagen IV0Direct
Cryptochrome/photolyase FAD-binding domain0Direct
Fibronectin type II module0Direct
Myosin phosphatase inhibitor 17kDa protein, CPI-170Direct
UDP-glucose pyrophosphorylase0Direct
Smc hinge domain0Direct
Troponin I0Direct
P4 origin-binding domain-like0Direct
Eferin C-derminal domain-like0Direct
VHS domain0Direct
Carboxylesterase/thioesterase 10Direct
beta-sandwich domain of Sec23/240Direct
SRF-like0Direct
Ubiquitin activating enzymes (UBA)0Direct
Heat shock protein 70kD (HSP70), peptide-binding domain0Direct
SH3BGR (SH3-binding, glutamic acid-rich protein-like)0Direct
AraD-like aldolase/epimerase0Direct
THAP domain0Direct
Fibronectin type I module0Direct
L30e/L7ae ribosomal proteins0Direct
SEA domain0Direct
Heat shock protein 90, HSP90, N-terminal domain0Direct
DNase I-like0Direct
Sec1/munc18-like (SM) proteins0Direct
Insulin-like0Direct
TNF receptor-like0Direct
EF-G/eEF-2 domains III and V0Direct
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain0Direct
MHC antigen-recognition domain0Direct
GRAM domain0Direct
PA domain0Direct
HR1 repeat0Direct
Lipovitellin-phosvitin complex; beta-sheet shell regions0Direct
NagB-like0Direct
NTF2-like0Direct
Enolase N-terminal domain-like0Direct
Homocysteine S-methyltransferase0Direct
alpha-mannosidase0Direct
Nuclear receptor coactivator interlocking domain0Direct
4HBT-like0Direct
Lectin leg-like0Direct
HAT/Suf repeat0Direct
E2F dimerization segment0Direct
Reductases0Direct
Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain0Direct
Phosphatidylethanolamine binding protein0Direct
S-adenosylhomocystein hydrolase0Direct
Guanido kinase N-terminal domain0Direct
Crotonase-like0Direct
Hsp90 middle domain0Direct
FF domain0Direct
LDH N-terminal domain-like0Direct
Serine carboxypeptidase-like0Direct
Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain0Direct
Arginase-like amidino hydrolases0Direct
SMAD domain0Direct
Tudor domain0Direct
FMN-linked oxidoreductases0Direct
Cryptochrome/photolyase, N-terminal domain0Direct
Proteasome activator0Direct
PDI-like0Direct
Scavenger receptor cysteine-rich (SRCR) domain0Direct
Sir2 family of transcriptional regulators0Direct
Group II chaperonin (CCT, TRIC), intermediate domain0Direct
SCF ubiquitin ligase complex WHB domain0Direct
alpha-ketoacid dehydrogenase kinase, N-terminal domain0Direct
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain0Direct
SMAD MH1 domain0Direct
Ubiquitin carboxyl-terminal hydrolase UCH-L0Direct
Glycolipid transfer protein, GLTP0Direct
HCP-like0Direct
BSD domain0Direct
Chitinase insertion domain0Direct
Alanine racemase-like, N-terminal domain0Direct
C-terminal, gelsolin-like domain of Sec23/240Direct
Formate/glycerate dehydrogenases, NAD-domain0Direct
Outer arm dynein light chain 10Direct
Eukaryotic ODC-like0Direct
B56-like0Direct
Retinol binding protein-like0Direct
Transferrin0Direct
DNA polymerase beta, N-terminal domain-like0Direct
Oxysterol-binding protein0Direct
Cullin homology domain0Direct
GS domain0Direct
Band 7/SPFH domain0Direct
Amidase signature (AS) enzymes0Direct
Lactate & malate dehydrogenases, C-terminal domain0Direct
FtsH protease domain-like0Direct
HD domain0Direct
Complement components0Direct
Surp module (SWAP domain)0Direct
Adenylyl and guanylyl cyclase catalytic domain0Direct
MIR domain0Direct
Cu,Zn superoxide dismutase-like0Direct
LeuD-like0Direct
Lipovitellin-phosvitin complex, superhelical domain0Direct
Delta-sleep-inducing peptide immunoreactive peptide0Direct
DNA repair protein MutS, domain III0Direct
Guanido kinase catalytic domain0Direct
Branched-chain alpha-keto acid dehydrogenase PP module0Direct
Cofilin-like0Direct
Ribonuclease PH domain 1-like0Direct
Heat shock protein 70kD (HSP70), C-terminal subdomain0Direct
Mannose 6-phosphate receptor domain0Direct
UBX domain0Direct
MAPEG domain0Direct
Tim10/DDP0Direct
Actin/HSP700Direct
RWD domain0Direct
Creatinase/aminopeptidase0Direct
ets domain0Direct
Autophagin-like0Direct
RuBisCo LSMT catalytic domain0Direct
NIPSNAP0Direct
Domain G2 of nidogen-10Direct
alpha-Amylases, C-terminal beta-sheet domain0Direct
Protein serine/threonine phosphatase0Direct
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex0Direct
alpha-catenin/vinculin0Direct
Glyoxalase II (hydroxyacylglutathione hydrolase)0Direct
alpha-mannosidase, C-terminal domain0Direct
TRAPP components0Direct
Amylase, catalytic domain0Direct
MSP-like0Direct
C1 set domains (antibody constant domain-like)0Direct
Hedgehog (development protein), N-terminal signaling domain0Direct
WGR domain0Direct
Inosine monophosphate dehydrogenase (IMPDH)0Direct
Nop domain0Direct
Ran-binding domain0Direct
Neurotrophin0Direct
BRK domain-like0Direct
PAS domain of steroid receptor coactivator 1A, NCo-A10Direct
Supernatant protein factor (SPF), C-terminal domain0Direct
ADP-ribosylglycohydrolase0Direct
JAB1/MPN domain0Direct
C-terminal domain of adenylylcyclase associated protein0Direct
(Glycosyl)asparaginase0Direct
Clathrin adaptor appendage, alpha and beta chain-specific domain0Direct
D-aminoacid oxidase-like0Direct
Kinase associated domain 1, KA10Direct
VHP, Villin headpiece domain0Direct
ECR1 N-terminal domain-like0Direct
Trunk domain of Sec23/240Direct
eIF1-like0Direct
Synatpobrevin N-terminal domain0Direct
Apolipoprotein A-I0Direct
Cytidylyltransferase0Direct
N-acetylmuramoyl-L-alanine amidase-like0Direct
LON domain-like0Direct
HSP90 C-terminal domain0Direct
RNA-polymerase beta0Direct
gamma-adaptin C-terminal appendage domain-like0Direct
APC10-like0Direct
Variant RING domain0Direct
F1F0 ATP synthase subunit C0Direct
Aconitase iron-sulfur domain0Direct
Gamma-glutamyltranspeptidase-like0Direct
Cell cycle transcription factor e2f-dp0Direct
Pointed domain0Direct
DnaJ/Hsp40 cysteine-rich domain0Direct
RhoGDI-like0Direct
UDPGT-like0Direct
Fibrinogen coiled-coil and central regions0Direct
Fumble-like0Direct
Cofactor-dependent phosphoglycerate mutase0Direct
USP8 N-terminal domain-like0Direct
Chromo barrel domain0Direct
Polo-box duplicated region0Direct
TSP type-3 repeat0Direct
DNA polymerase III clamp loader subunits, C-terminal domain0Direct
Netrin-like domain (NTR/C345C module)0Direct
Mib/herc2 domain0Direct
Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain0Direct
Choline/Carnitine O-acyltransferase0Direct
SAP domain0Direct
SIAH, seven in absentia homolog0Direct
HEAT repeat0Direct
PUA domain0Direct
MutT-like0Direct
Transducin (alpha subunit), insertion domain0Direct
PAZ domain0Direct
TRASH domain0Direct
Cullin repeat0Direct
Sedlin (SEDL)0Direct
AAT-like0Direct
BAG domain0Direct
U-box0Direct
Alpha-macroglobulin receptor domain0Direct
DNA ligase0Direct
Pumilio repeat0Direct
alpha-ketoacid dehydrogenase kinase, C-terminal domain0Direct
Threonyl-tRNA synthetase (ThrRS), second 'additional' domain0Direct
Succinyl-CoA synthetase domains0Direct
UBC-related0Direct
IF2B-like0Direct
GABARAP-like0Direct
Phosphoribosylpyrophosphate synthetase-like0Direct
alpha-mannosidase, domain 20Direct
TB module/8-cys domain0Direct
IP3 receptor type 1 binding core, domain 20Direct
Neutral endopeptidase (neprilysin)0Direct
Class I glutamine amidotransferases (GAT)0Direct
Aminomethyltransferase beta-barrel domain0Direct
Type II chitinase0Direct
L27 domain0Direct
Helical domain of Sec23/240Direct
Thrombospondin C-terminal domain0Direct
Other IPT/TIG domains0Direct
MIT domain0Direct
Alpha-adaptin ear subdomain-like0Direct
XPF/Rad1/Mus81 nuclease0Direct
Ribonuclease PH domain 2-like0Direct
N-type ATP pyrophosphatases0Direct
Ammonium transporter0Direct
RPR domain (SMART 00582 )0Direct
Protein-L-isoaspartyl O-methyltransferase0Direct
Cap-Gly domain0Direct
Inositol polyphosphate 5-phosphatase (IPP5)0Direct
Zf-UBP0Direct
Tandem AAA-ATPase domain0.0001488Direct
WD40-repeat0.001109Inherited
Canonical RBD0.001268Inherited
PHD domain0.006641Inherited
Extended AAA-ATPase domain0.02448Inherited
Tropomyosin0.08233Inherited
LIM domain0.09314Inherited
GABA-aminotransferase-like0.1245Inherited
ALDH-like0.1884Inherited
Hairy Orange domain0.2262Inherited
Leukotriene A4 hydrolase N-terminal domain0.2262Inherited
Leukotriene A4 hydrolase catalytic domain0.2262Inherited
Hypoxia-inducible factor Hif2a, C-terminal domain0.2352Inherited
ARID domain0.2689Inherited
Eukaryotic proteases0.2689Inherited
Class I aldolase0.3278Inherited
28-residue LRR0.3399Inherited
Growth factor receptor domain0.3425Inherited
Glutathione peroxidase-like0.3905Inherited
Erythroid transcription factor GATA-10.4647Inherited
Laminin G-like module0.4811Inherited
G proteins0.4829Inherited
HMG-box0.4937Inherited
Extracellular domain of cell surface receptors0.5294Inherited
Parvalbumin0.8001Inherited
Calmodulin-like0.9242Inherited
Frizzled cysteine-rich domain1Inherited
T-box1Inherited
Homeodomain1Inherited
Transforming growth factor (TGF)-beta1Inherited
Forkhead DNA-binding domain1Inherited
POU-specific domain1Inherited
HLH, helix-loop-helix DNA-binding domain1Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
Plot tree as:   Download Newick format tree:
(show help)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Aconitase iron-sulfur domain0Direct
Nop domain0Direct
Band 7/SPFH domain0Direct
TK C-terminal domain-like0Direct
NTF2-like0Direct
JAB1/MPN domain0Direct
Cap-Gly domain0Direct
Phosphoglucomutase, C-terminal domain0Direct
BSD domain-like0Direct
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Homocysteine S-methyltransferase0Direct
SPOC domain-like0Direct
Formate/glycerate dehydrogenase catalytic domain-like0Direct
Sec63 N-terminal domain-like0Direct
Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain0Direct
GFP-like0Direct
HR1 repeat0Direct
Cullin repeat-like0Direct
Myosin phosphatase inhibitor 17kDa protein, CPI-170Direct
C-terminal domain of adenylylcyclase associated protein0Direct
PLP-binding barrel0Direct
L27 domain0Direct
Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain0Direct
Thiolase-like0Direct
Supernatant protein factor (SPF), C-terminal domain0Direct
beta-sandwich domain of Sec23/240Direct
DNA polymerase beta, N-terminal domain-like0Direct
Smc hinge domain0Direct
Lipovitellin-phosvitin complex; beta-sheet shell regions0Direct
RNase III domain-like0Direct
Guanido kinase N-terminal domain0Direct
Surp module (SWAP domain)0Direct
Succinyl-CoA synthetase domains0Direct
ADP-ribosylglycohydrolase0Direct
Sec1/munc18-like (SM) proteins0Direct
Ammonium transporter0Direct
Eferin C-derminal domain-like0Direct
4Fe-4S ferredoxins0Direct
ThrRS/AlaRS common domain0Direct
MAPEG domain-like0Direct
TGS-like0Direct
FtsH protease domain-like0Direct
SRF-like0Direct
Invertebrate chitin-binding proteins0Direct
Creatinase/prolidase N-terminal domain0Direct
DNA repair protein MutS, domain III0Direct
Helical domain of Sec23/240Direct
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0Direct
DNA clamp0Direct
EF-G C-terminal domain-like0Direct
Subunits of heterodimeric actin filament capping protein Capz0Direct
Apolipoprotein A-I0Direct
Phosphoglucomutase, first 3 domains0Direct
FAD-linked oxidoreductase0Direct
FF domain0Direct
Nuclear receptor coactivator interlocking domain0Direct
FAD-binding/transporter-associated domain-like0Direct
BRK domain-like0Direct
post-AAA+ oligomerization domain-like0Direct
Nucleoside diphosphate kinase, NDK0Direct
DHS-like NAD/FAD-binding domain0Direct
Thioesterase/thiol ester dehydrase-isomerase0Direct
Inosine monophosphate dehydrogenase (IMPDH)0Direct
Zn-finger domain of Sec23/240Direct
Subdomain of clathrin and coatomer appendage domain0Direct
PABC (PABP) domain0Direct
PapD-like0Direct
Heat shock protein 70kD (HSP70), C-terminal subdomain0Direct
Adenine nucleotide alpha hydrolases-like0Direct
Endosomal sorting complex assembly domain0Direct
Delta-sleep-inducing peptide immunoreactive peptide0Direct
LeuD/IlvD-like0Direct
Moesin tail domain0Direct
Galactose mutarotase-like0Direct
Amidase signature (AS) enzymes0Direct
NagB/RpiA/CoA transferase-like0Direct
E2F-DP heterodimerization region0Direct
Cryptochrome/photolyase, N-terminal domain0Direct
Tricorn protease domain 20Direct
USP8 N-terminal domain-like0Direct
Aminomethyltransferase beta-barrel domain0Direct
IP3 receptor type 1 binding core, domain 20Direct
Creatinase/aminopeptidase0Direct
TSP type-3 repeat0Direct
Hedgehog/DD-peptidase0Direct
Cytidine deaminase-like0Direct
2Fe-2S ferredoxin-like0Direct
Clathrin adaptor appendage domain0Direct
G protein-binding domain0Direct
HSP90 C-terminal domain0Direct
F1F0 ATP synthase subunit C0Direct
TB module/8-cys domain0Direct
Alanine racemase C-terminal domain-like0Direct
Ligand-binding domain in the NO signalling and Golgi transport0Direct
Heat shock protein 70kD (HSP70), peptide-binding domain0Direct
Isocitrate/Isopropylmalate dehydrogenase-like0Direct
alpha-catenin/vinculin-like0Direct
Enolase C-terminal domain-like0Direct
Elongation factor TFIIS domain 20Direct
SAP domain0Direct
Thiamin diphosphate-binding fold (THDP-binding)0Direct
TNF receptor-like0Direct
Fibrinogen coiled-coil and central regions0Direct
GAT-like domain0Direct
AraD/HMP-PK domain-like0Direct
Insulin-like0Direct
Activating enzymes of the ubiquitin-like proteins0Direct
Carbon-nitrogen hydrolase0Direct
DnaJ/Hsp40 cysteine-rich domain0Direct
Mannose 6-phosphate receptor domain0Direct
BAG domain0Direct
RCC1/BLIP-II0Direct
RmlC-like cupins0Direct
NAP-like0Direct
SCP-like0Direct
L-aspartase-like0Direct
Mib/herc2 domain-like0Direct
Glycolipid transfer protein, GLTP0Direct
Chitinase insertion domain0Direct
LDH C-terminal domain-like0Direct
PAH2 domain0Direct
Transducin (alpha subunit), insertion domain0Direct
PEBP-like0Direct
Oligoxyloglucan reducing end-specific cellobiohydrolase0Direct
MIT domain0Direct
6-phosphogluconate dehydrogenase C-terminal domain-like0Direct
WGR domain-like0Direct
MIR domain0Direct
Alpha-macroglobulin receptor domain0Direct
Restriction endonuclease-like0Direct
ClpS-like0Direct
Nucleoporin domain0Direct
eIF1-like0Direct
Ribonuclease PH domain 2-like0Direct
Families 57/38 glycoside transferase middle domain0Direct
HRDC-like0Direct
N-acetylmuramoyl-L-alanine amidase-like0Direct
CoA-dependent acyltransferases0Direct
FabD/lysophospholipase-like0Direct
The spindle assembly checkpoint protein mad20Direct
UBC-like0Direct
VHP, Villin headpiece domain0Direct
C-terminal, gelsolin-like domain of Sec23/240Direct
occludin/ELL-like0Direct
FMT C-terminal domain-like0Direct
Ribosomal proteins S24e, L23 and L15e0Direct
SMAD MH1 domain0Direct
Nucleotide cyclase0Direct
ValRS/IleRS/LeuRS editing domain0Direct
ACP-like0Direct
Glutamine synthetase/guanido kinase0Direct
alpha-ketoacid dehydrogenase kinase, N-terminal domain0Direct
DUSP-like0Direct
Enolase N-terminal domain-like0Direct
Lipovitellin-phosvitin complex, superhelical domain0Direct
S15/NS1 RNA-binding domain0Direct
Cation efflux protein cytoplasmic domain-like0Direct
SIS domain0Direct
Zinc beta-ribbon0Direct
Tim10-like0Direct
Domain of poly(ADP-ribose) polymerase0Direct
MHC antigen-recognition domain0Direct
PAZ domain0Direct
Cryptochrome/photolyase FAD-binding domain0Direct
PA domain0Direct
Cu,Zn superoxide dismutase-like0Direct
Notch domain0Direct
Oxysterol-binding protein-like0Direct
Cullin homology domain0Direct
FMN-linked oxidoreductases0Direct
Proteasome activator0Direct
KA1-like0Direct
THUMP domain-like0Direct
GYF domain0Direct
ARM repeat0.00002313Direct
WD40 repeat-like0.0001609Direct
Ribonuclease H-like0.0003406Direct
NAD(P)-binding Rossmann-fold domains0.0008111Direct
Tudor/PWWP/MBT0.002368Inherited
Actin-like ATPase domain0.002939Inherited
P-loop containing nucleoside triphosphate hydrolases0.004465Inherited
RNA-binding domain, RBD0.005607Inherited
Translation proteins0.05117Inherited
PYP-like sensor domain (PAS domain)0.05943Inherited
FYVE/PHD zinc finger0.1327Inherited
SMAD/FHA domain0.1521Inherited
Tropomyosin0.1615Inherited
PLP-dependent transferases0.1804Inherited
Leukotriene A4 hydrolase N-terminal domain0.1931Inherited
ALDH-like0.1991Inherited
Growth factor receptor domain0.2006Inherited
"Winged helix" DNA-binding domain0.2141Inherited
TIMP-like0.2312Inherited
Orange domain-like0.2334Inherited
Clavaminate synthase-like0.2621Inherited
ARID-like0.2813Inherited
Translation proteins SH3-like domain0.2813Inherited
Thioredoxin-like0.3896Inherited
Translational machinery components0.4005Inherited
Zn-binding ribosomal proteins0.4754Inherited
Trypsin-like serine proteases0.4997Inherited
HMG-box0.523Inherited
EGF/Laminin0.6234Inherited
FnI-like domain0.6455Inherited
SAM/Pointed domain0.7121Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.7392Inherited
Snake toxin-like0.7956Inherited
EF-hand0.8897Inherited
Troponin coil-coiled subunits0.9207Inherited
Cystine-knot cytokines1Inherited
Homeodomain-like1Inherited
p53-like transcription factors1Inherited
lambda repressor-like DNA-binding domains1Inherited
Frizzled cysteine-rich domain1Inherited
HLH, helix-loop-helix DNA-binding domain1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
74788,75632
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 0Direct
    103575,81296
  • 103575 - Plexin repeat
  • 81296 - E set domains
  • 0Direct
    53300,49265
  • 53300 - vWA-like
  • 49265 - Fibronectin type III
  • 0Direct
    52540,140990
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 140990 - FtsH protease domain-like
  • 0Direct
    82895,57424
  • 82895 - TSP-1 type 1 repeat
  • 57424 - LDL receptor-like module
  • 0Direct
    50447,54980
  • 50447 - Translation proteins
  • 54980 - EF-G C-terminal domain-like
  • 0Direct
    46785,144074
  • 46785 - "Winged helix" DNA-binding domain
  • 144074 - E2F-DP heterodimerization region
  • 0Direct
    53901,53901
  • 53901 - Thiolase-like
  • 53901 - Thiolase-like
  • 0Direct
    54236,50729
  • 54236 - Ubiquitin-like
  • 50729 - PH domain-like
  • 0Direct
    57196,50494
  • 57196 - EGF/Laminin
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    57196,63825
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 0Direct
    64356,49447
  • 64356 - SNARE-like
  • 49447 - Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor
  • 0Direct
    63825,57196
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 0Direct
    57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0Direct
    52087,101576
  • 52087 - CRAL/TRIO domain
  • 101576 - Supernatant protein factor (SPF), C-terminal domain
  • 0Direct
    50447,50465
  • 50447 - Translation proteins
  • 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
  • 0Direct
    57603,57440
  • 57603 - FnI-like domain
  • 57440 - Kringle-like
  • 0Direct
    55550,50729
  • 55550 - SH2 domain
  • 50729 - PH domain-like
  • 0Direct
    52540,47917
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase
  • 0Direct
    56968,48431
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 48431 - Lipovitellin-phosvitin complex, superhelical domain
  • 0Direct
    47370,47370
  • 47370 - Bromodomain
  • 47370 - Bromodomain
  • 0Direct
    64268,103657
  • 64268 - PX domain
  • 103657 - BAR/IMD domain-like
  • 0Direct
    54637,54637
  • 54637 - Thioesterase/thiol ester dehydrase-isomerase
  • 54637 - Thioesterase/thiol ester dehydrase-isomerase
  • 0Direct
    49265,56496
  • 49265 - Fibronectin type III
  • 56496 - Fibrinogen C-terminal domain-like
  • 0Direct
    52799,49562
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0Direct
    54211,54980
  • 54211 - Ribosomal protein S5 domain 2-like
  • 54980 - EF-G C-terminal domain-like
  • 0Direct
    57196,57535
  • 57196 - EGF/Laminin
  • 57535 - Complement control module/SCR domain
  • 0Direct
    53738,53738
  • 53738 - Phosphoglucomutase, first 3 domains
  • 53738 - Phosphoglucomutase, first 3 domains
  • 0Direct
    54768,54768
  • 54768 - dsRNA-binding domain-like
  • 54768 - dsRNA-binding domain-like
  • 0Direct
    57424,57184
  • 57424 - LDL receptor-like module
  • 57184 - Growth factor receptor domain
  • 0Direct
    57196,49854
  • 57196 - EGF/Laminin
  • 49854 - Spermadhesin, CUB domain
  • 0Direct
    55486,48371
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 48371 - ARM repeat
  • 0Direct
    47005,52777
  • 47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
  • 52777 - CoA-dependent acyltransferases
  • 0Direct
    82185,82185
  • 82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
  • 82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
  • 0Direct
    51419,50621
  • 51419 - PLP-binding barrel
  • 50621 - Alanine racemase C-terminal domain-like
  • 0Direct
    49854,57196
  • 49854 - Spermadhesin, CUB domain
  • 57196 - EGF/Laminin
  • 0Direct
    75632,46785
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    57850,49599
  • 57850 - RING/U-box
  • 49599 - TRAF domain-like
  • 0Direct
    57938,49493
  • 57938 - DnaJ/Hsp40 cysteine-rich domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 0Direct
    52518,52518
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 0Direct
    82109,82109
  • 82109 - MIR domain
  • 82109 - MIR domain
  • 0Direct
    81698,81698
  • 81698 - FF domain
  • 81698 - FF domain
  • 0Direct
    57581,57184
  • 57581 - TB module/8-cys domain
  • 57184 - Growth factor receptor domain
  • 0Direct
    48464,89009
  • 48464 - ENTH/VHS domain
  • 89009 - GAT-like domain
  • 0Direct
    51735,56327
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 56327 - LDH C-terminal domain-like
  • 0Direct
    81296,48239
  • 81296 - E set domains
  • 48239 - Terpenoid cyclases/Protein prenyltransferases
  • 0Direct
    53067,100920
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 0Direct
    53300,81995
  • 53300 - vWA-like
  • 81995 - beta-sandwich domain of Sec23/24
  • 0Direct
    57196,100895
  • 57196 - EGF/Laminin
  • 100895 - Kazal-type serine protease inhibitors
  • 0Direct
    100920,100934
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
  • 0Direct
    57889,50729
  • 57889 - Cysteine-rich domain
  • 50729 - PH domain-like
  • 0Direct
    103647,103647
  • 103647 - TSP type-3 repeat
  • 103647 - TSP type-3 repeat
  • 0Direct
    54534,47473
  • 54534 - FKBP-like
  • 47473 - EF-hand
  • 0Direct
    50998,50978
  • 50998 - Quinoprotein alcohol dehydrogenase-like
  • 50978 - WD40 repeat-like
  • 0Direct
    52777,52777
  • 52777 - CoA-dependent acyltransferases
  • 52777 - CoA-dependent acyltransferases
  • 0Direct
    50044,50156
  • 50044 - SH3-domain
  • 50156 - PDZ domain-like
  • 0Direct
    54534,54534
  • 54534 - FKBP-like
  • 54534 - FKBP-like
  • 0Direct
    53732,52016
  • 53732 - Aconitase iron-sulfur domain
  • 52016 - LeuD/IlvD-like
  • 0Direct
    54452,48726
  • 54452 - MHC antigen-recognition domain
  • 48726 - Immunoglobulin
  • 0Direct
    46565,57938
  • 46565 - Chaperone J-domain
  • 57938 - DnaJ/Hsp40 cysteine-rich domain
  • 0Direct
    101690,53098
  • 101690 - PAZ domain
  • 53098 - Ribonuclease H-like
  • 0Direct
    54403,54403
  • 54403 - Cystatin/monellin
  • 54403 - Cystatin/monellin
  • 0Direct
    48371,46785
  • 48371 - ARM repeat
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    55785,55785
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0Direct
    57196,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0Direct
    103647,49899
  • 103647 - TSP type-3 repeat
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    51045,56204
  • 51045 - WW domain
  • 56204 - Hect, E3 ligase catalytic domain
  • 0Direct
    57903,51197
  • 57903 - FYVE/PHD zinc finger
  • 51197 - Clavaminate synthase-like
  • 0Direct
    48334,52540
  • 48334 - DNA repair protein MutS, domain III
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    52540,48340
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 48340 - Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain
  • 0Direct
    110324,50249
  • 110324 - Ribosomal L27 protein-like
  • 50249 - Nucleic acid-binding proteins
  • 0Direct
    52540,50447
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 0Direct
    53850,53850
  • 53850 - Periplasmic binding protein-like II
  • 53850 - Periplasmic binding protein-like II
  • 0Direct
    100895,47473
  • 100895 - Kazal-type serine protease inhibitors
  • 47473 - EF-hand
  • 0Direct
    54160,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    50677,52374
  • 50677 - ValRS/IleRS/LeuRS editing domain
  • 52374 - Nucleotidylyl transferase
  • 0Direct
    52540,46785
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    54160,57850
  • 54160 - Chromo domain-like
  • 57850 - RING/U-box
  • 0Direct
    117281,50965
  • 117281 - Kelch motif
  • 50965 - Galactose oxidase, central domain
  • 0Direct
    88713,88688
  • 88713 - Glycoside hydrolase/deacetylase
  • 88688 - Families 57/38 glycoside transferase middle domain
  • 0Direct
    56059,52210
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 52210 - Succinyl-CoA synthetase domains
  • 0Direct
    52283,51735
  • 52283 - Formate/glycerate dehydrogenase catalytic domain-like
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0Direct
    47095,47095
  • 47095 - HMG-box
  • 47095 - HMG-box
  • 0Direct
    81995,81811
  • 81995 - beta-sandwich domain of Sec23/24
  • 81811 - Helical domain of Sec23/24
  • 0Direct
    82615,82615
  • 82615 - Polo-box domain
  • 82615 - Polo-box domain
  • 0Direct
    54511,57184
  • 54511 - GFP-like
  • 57184 - Growth factor receptor domain
  • 0Direct
    52540,48019
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 48019 - post-AAA+ oligomerization domain-like
  • 0Direct
    47986,52129
  • 47986 - DEATH domain
  • 52129 - Caspase-like
  • 0Direct
    52058,49265
  • 52058 - L domain-like
  • 49265 - Fibronectin type III
  • 0Direct
    57924,57924
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 0Direct
    52425,48173
  • 52425 - Cryptochrome/photolyase, N-terminal domain
  • 48173 - Cryptochrome/photolyase FAD-binding domain
  • 0Direct
    46942,57783
  • 46942 - Elongation factor TFIIS domain 2
  • 57783 - Zinc beta-ribbon
  • 0Direct
    57440,50494
  • 57440 - Kringle-like
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    57184,57610
  • 57184 - Growth factor receptor domain
  • 57610 - Thyroglobulin type-1 domain
  • 0Direct
    57630,57196
  • 57630 - GLA-domain
  • 57196 - EGF/Laminin
  • 0Direct
    82919,53300
  • 82919 - Zn-finger domain of Sec23/24
  • 53300 - vWA-like
  • 0Direct
    49899,52540
  • 49899 - Concanavalin A-like lectins/glucanases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    74650,51445
  • 74650 - Galactose mutarotase-like
  • 51445 - (Trans)glycosidases
  • 0Direct
    57184,57581
  • 57184 - Growth factor receptor domain
  • 57581 - TB module/8-cys domain
  • 0Direct
    55753,82754
  • 55753 - Actin depolymerizing proteins
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0Direct
    56112,55073
  • 56112 - Protein kinase-like (PK-like)
  • 55073 - Nucleotide cyclase
  • 0Direct
    48350,50729
  • 48350 - GTPase activation domain, GAP
  • 50729 - PH domain-like
  • 0Direct
    101288,50156
  • 101288 - L27 domain
  • 50156 - PDZ domain-like
  • 0Direct
    82109,100909
  • 82109 - MIR domain
  • 100909 - IP3 receptor type 1 binding core, domain 2
  • 0Direct
    50494,50494
  • 50494 - Trypsin-like serine proteases
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    81271,55186
  • 81271 - TGS-like
  • 55186 - ThrRS/AlaRS common domain
  • 0Direct
    47220,47220
  • 47220 - alpha-catenin/vinculin-like
  • 47220 - alpha-catenin/vinculin-like
  • 0Direct
    69012,55874
  • 69012 - alpha-ketoacid dehydrogenase kinase, N-terminal domain
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 0Direct
    81811,82754
  • 81811 - Helical domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0Direct
    90209,90209
  • 90209 - Ran binding protein zinc finger-like
  • 90209 - Ran binding protein zinc finger-like
  • 0Direct
    50978,50978
  • 50978 - WD40 repeat-like
  • 50978 - WD40 repeat-like
  • 0Direct
    52833,52833
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 0Direct
    46585,46585
  • 46585 - HR1 repeat
  • 46585 - HR1 repeat
  • 0Direct
    54211,55666
  • 54211 - Ribosomal protein S5 domain 2-like
  • 55666 - Ribonuclease PH domain 2-like
  • 0Direct
    50156,50044
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 0Direct
    57581,57196
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 0Direct
    57903,47370
  • 57903 - FYVE/PHD zinc finger
  • 47370 - Bromodomain
  • 0Direct
    48403,50044
  • 48403 - Ankyrin repeat
  • 50044 - SH3-domain
  • 0Direct
    161111,160240
  • 161111 - Cation efflux protein transmembrane domain-like
  • 160240 - Cation efflux protein cytoplasmic domain-like
  • 0Direct
    142921,47587
  • 142921 - WGR domain-like
  • 47587 - Domain of poly(ADP-ribose) polymerase
  • 0Direct
    54980,54211
  • 54980 - EF-G C-terminal domain-like
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0Direct
    50729,57863
  • 50729 - PH domain-like
  • 57863 - ArfGap/RecO-like zinc finger
  • 0Direct
    47587,56399
  • 47587 - Domain of poly(ADP-ribose) polymerase
  • 56399 - ADP-ribosylation
  • 0Direct
    51230,47005
  • 51230 - Single hybrid motif
  • 47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
  • 0Direct
    52518,52922
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 52922 - TK C-terminal domain-like
  • 0Direct
    57196,57581
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 0Direct
    57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0Direct
    69065,54768
  • 69065 - RNase III domain-like
  • 54768 - dsRNA-binding domain-like
  • 0Direct
    103657,50729
  • 103657 - BAR/IMD domain-like
  • 50729 - PH domain-like
  • 0Direct
    51735,48179
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
  • 0Direct
    50729,55550
  • 50729 - PH domain-like
  • 55550 - SH2 domain
  • 0Direct
    48592,54849
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 0Direct
    47473,103506
  • 47473 - EF-hand
  • 103506 - Mitochondrial carrier
  • 0Direct
    57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0Direct
    47895,52540
  • 47895 - Transducin (alpha subunit), insertion domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    51445,54556
  • 51445 - (Trans)glycosidases
  • 54556 - Chitinase insertion domain
  • 0Direct
    53738,55957
  • 53738 - Phosphoglucomutase, first 3 domains
  • 55957 - Phosphoglucomutase, C-terminal domain
  • 0Direct
    52540,53254
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 53254 - Phosphoglycerate mutase-like
  • 0Direct
    49348,55711
  • 49348 - Clathrin adaptor appendage domain
  • 55711 - Subdomain of clathrin and coatomer appendage domain
  • 0Direct
    82754,55753
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 55753 - Actin depolymerizing proteins
  • 0Direct
    57184,49899
  • 57184 - Growth factor receptor domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    103025,101790
  • 103025 - Folate-binding domain
  • 101790 - Aminomethyltransferase beta-barrel domain
  • 0Direct
    48034,55931
  • 48034 - Guanido kinase N-terminal domain
  • 55931 - Glutamine synthetase/guanido kinase
  • 0Direct
    55681,52954
  • 55681 - Class II aaRS and biotin synthetases
  • 52954 - Class II aaRS ABD-related
  • 0Direct
    52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.0002088Direct
    53067,53067
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 0.006709Inherited
    48371,48371
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 0.01754Inherited
    57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.1426Inherited
    47459,55785
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.1874Inherited
    63737,55486
  • 63737 - Leukotriene A4 hydrolase N-terminal domain
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0.1931Inherited
    47459,158457
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 158457 - Orange domain-like
  • 0.2334Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.245Inherited
    54928,54928
  • 54928 - RNA-binding domain, RBD
  • 54928 - RNA-binding domain, RBD
  • 0.47Inherited
    57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.4974Inherited
    54791,54791
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 0.7126Inherited
    49899,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.9426Inherited
    47413,46689
  • 47413 - lambda repressor-like DNA-binding domains
  • 46689 - Homeodomain-like
  • 1Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57184,57196,57184
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0Direct
    103657,50729,48350
  • 103657 - BAR/IMD domain-like
  • 50729 - PH domain-like
  • 48350 - GTPase activation domain, GAP
  • 0Direct
    74788,75632,46785
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    57184,52058,49265
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 49265 - Fibronectin type III
  • 0Direct
    46938,52087,101576
  • 46938 - CRAL/TRIO N-terminal domain
  • 52087 - CRAL/TRIO domain
  • 101576 - Supernatant protein factor (SPF), C-terminal domain
  • 0Direct
    142921,47587,56399
  • 142921 - WGR domain-like
  • 47587 - Domain of poly(ADP-ribose) polymerase
  • 56399 - ADP-ribosylation
  • 0Direct
    63825,57196,63825
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 0Direct
    81995,81811,82754
  • 81995 - beta-sandwich domain of Sec23/24
  • 81811 - Helical domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0Direct
    57440,57440,50494
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    46565,57938,49493
  • 46565 - Chaperone J-domain
  • 57938 - DnaJ/Hsp40 cysteine-rich domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 0Direct
    53067,53067,100920
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 0Direct
    57196,57535,57535
  • 57196 - EGF/Laminin
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0Direct
    57424,57184,63825
  • 57424 - LDL receptor-like module
  • 57184 - Growth factor receptor domain
  • 63825 - YWTD domain
  • 0Direct
    52540,50447,50465
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
  • 0Direct
    57850,49599,49599
  • 57850 - RING/U-box
  • 49599 - TRAF domain-like
  • 49599 - TRAF domain-like
  • 0Direct
    49899,57196,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    57184,57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0Direct
    53738,53738,53738
  • 53738 - Phosphoglucomutase, first 3 domains
  • 53738 - Phosphoglucomutase, first 3 domains
  • 53738 - Phosphoglucomutase, first 3 domains
  • 0Direct
    57581,57196,57196
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0Direct
    57440,57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0Direct
    103647,103647,49899
  • 103647 - TSP type-3 repeat
  • 103647 - TSP type-3 repeat
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    103657,50729,57863
  • 103657 - BAR/IMD domain-like
  • 50729 - PH domain-like
  • 57863 - ArfGap/RecO-like zinc finger
  • 0Direct
    53738,53738,55957
  • 53738 - Phosphoglucomutase, first 3 domains
  • 53738 - Phosphoglucomutase, first 3 domains
  • 55957 - Phosphoglucomutase, C-terminal domain
  • 0Direct
    53067,100920,100934
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
  • 0Direct
    103647,103647,103647
  • 103647 - TSP type-3 repeat
  • 103647 - TSP type-3 repeat
  • 103647 - TSP type-3 repeat
  • 0Direct
    54980,54211,54980
  • 54980 - EF-G C-terminal domain-like
  • 54211 - Ribosomal protein S5 domain 2-like
  • 54980 - EF-G C-terminal domain-like
  • 0Direct
    54511,57184,57184
  • 54511 - GFP-like
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0Direct
    50249,50249,50249
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 0Direct
    54768,54768,54768
  • 54768 - dsRNA-binding domain-like
  • 54768 - dsRNA-binding domain-like
  • 54768 - dsRNA-binding domain-like
  • 0Direct
    49785,49785,49899
  • 49785 - Galactose-binding domain-like
  • 49785 - Galactose-binding domain-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    54791,54791,54791
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 0Direct
    50156,50044,52540
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    47459,55785,55785
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0Direct
    50447,54980,54211
  • 50447 - Translation proteins
  • 54980 - EF-G C-terminal domain-like
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0Direct
    57630,57196,57196
  • 57630 - GLA-domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0Direct
    56436,56436,56436
  • 56436 - C-type lectin-like
  • 56436 - C-type lectin-like
  • 56436 - C-type lectin-like
  • 0Direct
    57196,63825,57196
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 0Direct
    52540,52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    57424,57424,57184
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57184 - Growth factor receptor domain
  • 0Direct
    103575,81296,81296
  • 103575 - Plexin repeat
  • 81296 - E set domains
  • 81296 - E set domains
  • 0Direct
    52540,50447,54980
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 54980 - EF-G C-terminal domain-like
  • 0Direct
    57196,57581,57196
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 0Direct
    50729,55550,56112
  • 50729 - PH domain-like
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    55550,56112,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    54160,52540,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    49854,57196,49854
  • 49854 - Spermadhesin, CUB domain
  • 57196 - EGF/Laminin
  • 49854 - Spermadhesin, CUB domain
  • 0Direct
    57196,49899,57196
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 0Direct
    48592,54849,52029
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0Direct
    74650,51445,51011
  • 74650 - Galactose mutarotase-like
  • 51445 - (Trans)glycosidases
  • 51011 - Glycosyl hydrolase domain
  • 0Direct
    57196,57184,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0Direct
    57184,57184,57196
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0Direct
    57196,49854,57535
  • 57196 - EGF/Laminin
  • 49854 - Spermadhesin, CUB domain
  • 57535 - Complement control module/SCR domain
  • 0Direct
    50044,50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0Direct
    51230,47005,52777
  • 51230 - Single hybrid motif
  • 47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
  • 52777 - CoA-dependent acyltransferases
  • 0Direct
    57184,57581,57196
  • 57184 - Growth factor receptor domain
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 0Direct
    57581,57184,57581
  • 57581 - TB module/8-cys domain
  • 57184 - Growth factor receptor domain
  • 57581 - TB module/8-cys domain
  • 0Direct
    46689,46689,46689
  • 46689 - Homeodomain-like
  • 46689 - Homeodomain-like
  • 46689 - Homeodomain-like
  • 0Direct
    57196,57581,57184
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 57184 - Growth factor receptor domain
  • 0Direct
    57581,57196,57581
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 0Direct
    57196,57196,57581
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 0Direct
    47220,47220,47220
  • 47220 - alpha-catenin/vinculin-like
  • 47220 - alpha-catenin/vinculin-like
  • 47220 - alpha-catenin/vinculin-like
  • 0Direct
    52058,52058,52058
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 0Direct
    46585,46585,46585
  • 46585 - HR1 repeat
  • 46585 - HR1 repeat
  • 46585 - HR1 repeat
  • 0Direct
    54160,57850,57845
  • 54160 - Chromo domain-like
  • 57850 - RING/U-box
  • 57845 - B-box zinc-binding domain
  • 0Direct
    101288,50156,50044
  • 101288 - L27 domain
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 0Direct
    52058,49265,49265
  • 52058 - L domain-like
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0Direct
    52833,52833,52833
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 0Direct
    63737,55486,48371
  • 63737 - Leukotriene A4 hydrolase N-terminal domain
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 48371 - ARM repeat
  • 0Direct
    82109,82109,100909
  • 82109 - MIR domain
  • 82109 - MIR domain
  • 100909 - IP3 receptor type 1 binding core, domain 2
  • 0Direct
    51045,51045,56204
  • 51045 - WW domain
  • 51045 - WW domain
  • 56204 - Hect, E3 ligase catalytic domain
  • 0Direct
    54160,54160,52540
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    82754,55753,55753
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 0Direct
    53300,81995,81811
  • 53300 - vWA-like
  • 81995 - beta-sandwich domain of Sec23/24
  • 81811 - Helical domain of Sec23/24
  • 0Direct
    52743,49785,57184
  • 52743 - Subtilisin-like
  • 49785 - Galactose-binding domain-like
  • 57184 - Growth factor receptor domain
  • 0Direct
    57938,49493,49493
  • 57938 - DnaJ/Hsp40 cysteine-rich domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 0Direct
    57716,57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.1702Inherited
    49899,49899,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.2161Inherited
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.3211Inherited
    50044,55550,56112
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.3211Inherited
    57184,57196,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.4166Inherited
    48371,48371,48371
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 0.6593Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)