SUPERFAMILY 1.75 HMM library and genome assignments server

Superfamily is undergoing a server migration - you are now browsing on the new server. Please contact us if you experience any problems.

Yeast Phenotype (YP): cellular processes

(show info)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: YP Hierarchy (yeast phenotype from Ascomycete phenotype ontology)

Shortest distance to current term (+ for parents, - for children) YP term [YP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ 1:   observable [APO:0000017] <7>
0:   cellular processes [APO:0000066] <6>(218|225) (221|88|20)
- 1:   stress resistance [APO:0000080] <10>(186|199) (188|78|18)
- 1:   chromosome/plasmid maintenance [APO:0000143] <8>(12|10) (12|3|0)
- 1:   intracellular transport [APO:0000073] <6>(6|6) (7|1|1)
- 1:   mitotic cell cycle [APO:0000072] <5>(10|10) (10|2|0)
- 1:   cell death [APO:0000312] <4>(1|2) (1|0|0)
- 1:   prion state [APO:0000274] <3>(2|1) (2|0|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Retrovirus zinc finger-like domains0Direct
Arginase/deacetylase0Direct
Seven-hairpin glycosidases0Direct
ThrRS/AlaRS common domain0Direct
JAB1/MPN domain0Direct
Thiolase-like0Direct
post-AAA+ oligomerization domain-like0Direct
Ribonuclease PH domain 2-like0Direct
GINS helical bundle-like0Direct
Trimeric LpxA-like enzymes0Direct
HMA, heavy metal-associated domain0Direct
CorA soluble domain-like0Direct
HSP40/DnaJ peptide-binding domain0Direct
Glutathione synthetase ATP-binding domain-like0Direct
YVTN repeat-like/Quinoprotein amine dehydrogenase0Direct
tRNA-intron endonuclease catalytic domain-like0Direct
DNA-binding domain of Mlu1-box binding protein MBP10Direct
Tubulin nucleotide-binding domain-like0Direct
Single hybrid motif0Direct
F1F0 ATP synthase subunit C0Direct
LeuD/IlvD-like0Direct
Transferrin receptor-like dimerisation domain0Direct
Ypt/Rab-GAP domain of gyp1p0Direct
GAT-like domain0Direct
Zn-binding ribosomal proteins0Direct
Cation efflux protein transmembrane domain-like0Direct
SET domain0Direct
EPT/RTPC-like0Direct
Supernatant protein factor (SPF), C-terminal domain0Direct
Rudiment single hybrid motif0Direct
RmlC-like cupins0Direct
CoA-dependent acyltransferases0Direct
Heat shock protein 70kD (HSP70), C-terminal subdomain0Direct
Phosphoenolpyruvate/pyruvate domain0Direct
Ribosomal protein L30p/L7e0Direct
Tricorn protease domain 20Direct
NTF2-like0Direct
Zinc domain conserved in yeast copper-regulated transcription factors0Direct
Ras GEF0Direct
Phospholipase D/nuclease0Direct
DBL homology domain (DH-domain)0Direct
Ribosomal protein S80Direct
DNA repair protein MutS, domain II0Direct
Ribosomal L11/L12e N-terminal domain0Direct
Alpha-L RNA-binding motif0Direct
Translational machinery components0Direct
Inosine monophosphate dehydrogenase (IMPDH)0Direct
PriA/YqbF domain0Direct
PAP/OAS1 substrate-binding domain0Direct
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD0Direct
LuxS/MPP-like metallohydrolase0Direct
Helical domain of Sec23/240Direct
Zn-finger domain of Sec23/240Direct
POZ domain0Direct
Tubulin C-terminal domain-like0Direct
post-HMGL domain-like0Direct
Aldolase0Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0Direct
Ribosomal protein L140Direct
alpha/beta knot0Direct
R3H domain0Direct
Magnesium transport protein CorA, transmembrane region0Direct
Acid proteases0Direct
Tryptophan synthase beta subunit-like PLP-dependent enzymes0Direct
4'-phosphopantetheinyl transferase0Direct
C-terminal autoproteolytic domain of nucleoporin nup980Direct
Nucleoporin domain0Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase0Direct
PP2C-like0Direct
Ribonuclease H-like0Direct
L-aspartase-like0Direct
Kelch motif0Direct
RBP11-like subunits of RNA polymerase0Direct
TK C-terminal domain-like0Direct
EF-G C-terminal domain-like0Direct
Subtilisin-like0Direct
C-terminal, gelsolin-like domain of Sec23/240Direct
cAMP-binding domain-like0Direct
The spindle assembly checkpoint protein mad20Direct
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain0Direct
Sec63 N-terminal domain-like0Direct
Chromo domain-like0Direct
Terpenoid synthases0Direct
DNA/RNA polymerases0Direct
Cysteine alpha-hairpin motif0Direct
vWA-like0Direct
Calponin-homology domain, CH-domain0Direct
VPS9 domain0Direct
PreATP-grasp domain0Direct
KA1-like0Direct
Cdc48 domain 2-like0Direct
HD-domain/PDEase-like0Direct
Nucleotidylyl transferase0Direct
WW domain0Direct
YAP1 redox domain0Direct
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain0Direct
HRDC-like0Direct
DNA-glycosylase0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Sec7 domain0Direct
CBS-domain pair0Direct
ALDH-like0Direct
Class II aaRS ABD-related0Direct
CheY-like0Direct
FAD-linked oxidoreductase0Direct
Ribokinase-like0Direct
DNA repair protein MutS, domain I0Direct
Aquaporin-like0Direct
Fumarate reductase respiratory complex transmembrane subunits0Direct
Bromodomain0Direct
SAICAR synthase-like0Direct
FAD/NAD-linked reductases, dimerisation (C-terminal) domain0Direct
Actin depolymerizing proteins0Direct
Six-hairpin glycosidases0Direct
Ribosomal protein L60Direct
MurD-like peptide ligases, peptide-binding domain0Direct
SNARE-like0Direct
YjgF-like0Direct
L30e-like0Direct
Ribosomal protein S20Direct
PYP-like sensor domain (PAS domain)0Direct
Alkaline phosphatase-like0Direct
Glycoside hydrolase/deacetylase0Direct
Cytochrome c0Direct
eIF1-like0Direct
CRAL/TRIO N-terminal domain0Direct
Mitochondrial cytochrome c oxidase subunit IV0Direct
HLH, helix-loop-helix DNA-binding domain0Direct
Eukaryotic type KH-domain (KH-domain type I)0Direct
Clathrin adaptor appendage domain0Direct
Cap-Gly domain0Direct
CRAL/TRIO domain0Direct
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0Direct
Clavaminate synthase-like0Direct
FtsH protease domain-like0Direct
HIT/MYND zinc finger-like0Direct
DNA ligase/mRNA capping enzyme, catalytic domain0Direct
Ferritin-like0Direct
Family A G protein-coupled receptor-like0Direct
Smc hinge domain0Direct
Adenine nucleotide alpha hydrolases-like0Direct
Metallo-dependent hydrolases0Direct
Chaperone J-domain0Direct
Endosomal sorting complex assembly domain0Direct
Carbohydrate phosphatase0Direct
Cytidine deaminase-like0Direct
Prefoldin0Direct
LexA/Signal peptidase0Direct
Methylglyoxal synthase-like0Direct
Mss4-like0Direct
PA domain0Direct
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0Direct
Heat shock protein 70kD (HSP70), peptide-binding domain0Direct
Protein prenylyltransferase0Direct
Aconitase iron-sulfur domain0Direct
Amidase signature (AS) enzymes0Direct
Undecaprenyl diphosphate synthase0Direct
Ribosomal protein L11, C-terminal domain0Direct
ArfGap/RecO-like zinc finger0Direct
HMG-box0Direct
Restriction endonuclease-like0Direct
ValRS/IleRS/LeuRS editing domain0Direct
RNase III domain-like0Direct
Glutamine synthetase/guanido kinase0Direct
HSP20-like chaperones0Direct
Ribosomal protein L220Direct
Ribulose-phoshate binding barrel0Direct
RNI-like0Direct
BRCT domain0Direct
Regulator of G-protein signaling, RGS0Direct
Nucleotide-binding domain0Direct
Ribosomal protein L130Direct
Terpenoid cyclases/Protein prenyltransferases0Direct
SAP domain0Direct
Fe,Mn superoxide dismutase (SOD), C-terminal domain0Direct
Carbamate kinase-like0Direct
S13-like H2TH domain0Direct
Acetyl-CoA synthetase-like0Direct
GHMP Kinase, C-terminal domain0Direct
MurD-like peptide ligases, catalytic domain0Direct
Ligand-binding domain in the NO signalling and Golgi transport0Direct
GST C-terminal domain-like0Direct
PUA domain-like0Direct
HCP-like0Direct
FabD/lysophospholipase-like0Direct
Carbon-nitrogen hydrolase0Direct
Ribosomal protein L10-like0Direct
Metallo-hydrolase/oxidoreductase0Direct
GYF domain0Direct
beta-sandwich domain of Sec23/240Direct
PR-1-like0Direct
Nop domain0Direct
DNA repair protein MutS, domain III0Direct
Radical SAM enzymes0Direct
Cupredoxins0Direct
CCCH zinc finger0Direct
dsRNA-binding domain-like0Direct
Glucocorticoid receptor-like (DNA-binding domain)0Direct
Activating enzymes of the ubiquitin-like proteins0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
HIT-like0Direct
Zn-dependent exopeptidases0Direct
Cytochrome P4500Direct
FMN-binding split barrel0Direct
DnaJ/Hsp40 cysteine-rich domain0Direct
Protein kinase-like (PK-like)0.1415Inherited
ARM repeat0.1885Inherited
Nucleic acid-binding proteins0.2362Inherited
"Winged helix" DNA-binding domain0.2955Inherited
Class II aaRS and biotin synthetases0.3265Inherited
Ankyrin repeat0.3641Inherited
Translation proteins SH3-like domain0.4095Inherited
P-loop containing nucleoside triphosphate hydrolases0.5556Inherited
GroEL apical domain-like0.5945Inherited
Histone-fold0.6407Inherited
SH3-domain0.6407Inherited
5' to 3' exonuclease, C-terminal subdomain0.7955Inherited
Cyclophilin-like0.9067Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
PyrH-like0Direct
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD0Direct
Trunk domain of Sec23/240Direct
Ribosomal protein L11, C-terminal domain0Direct
Chaperone J-domain0Direct
YjgF/L-PSP0Direct
Adenosine/AMP deaminase0Direct
Pepsin-like0Direct
CheY-related0Direct
RNA-polymerase beta-prime0Direct
DNA polymerase I0Direct
LeuD-like0Direct
Glutathione S-transferase (GST), C-terminal domain0Direct
RecA protein-like (ATPase-domain)0Direct
Ferredoxin reductase FAD-binding domain-like0Direct
EF-G/eEF-2 domains III and V0Direct
FAD/NAD-linked reductases, N-terminal and central domains0Direct
Pumilio repeat0Direct
F1F0 ATP synthase subunit C0Direct
Inositol monophosphatase/fructose-1,6-bisphosphatase-like0Direct
NTF2-like0Direct
BC ATP-binding domain-like0Direct
Forkhead DNA-binding domain0Direct
DNA polymerase III clamp loader subunits, C-terminal domain0Direct
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain0Direct
Ribosomal L11/L12e N-terminal domain0Direct
Nucleosome core histones0Direct
HAT/Suf repeat0Direct
SAP domain0Direct
GYF domain0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Translational machinery components0Direct
Zinc domain conserved in yeast copper-regulated transcription factors0Direct
Group II chaperonin (CCT, TRIC), apical domain0Direct
Sir2 family of transcriptional regulators0Direct
Aconitase iron-sulfur domain0Direct
HSP40/DnaJ peptide-binding domain0Direct
Tryptophan synthase beta subunit-like PLP-dependent enzymes0Direct
Ribosomal protein L220Direct
FAD/NAD-linked reductases, dimerisation (C-terminal) domain0Direct
Ribosomal protein L14e0Direct
Bacteriorhodopsin-like0Direct
DNA repair protein MutS, domain III0Direct
Protein prenyltransferases0Direct
HLH, helix-loop-helix DNA-binding domain0Direct
Hexokinase0Direct
Retrovirus zinc finger-like domains0Direct
Inosine monophosphate dehydrogenase (IMPDH)0Direct
Pyk2-associated protein beta ARF-GAP domain0Direct
eIF1-like0Direct
Serine carboxypeptidase-like0Direct
Biotinyl/lipoyl-carrier proteins and domains0Direct
VPS9 domain0Direct
MIF4G domain-like0Direct
C-terminal, gelsolin-like domain of Sec23/240Direct
GHMP Kinase, N-terminal domain0Direct
Pseudouridine synthase I TruA0Direct
Glycosyl hydrolases family 160Direct
ALDH-like0Direct
Nucleotide and nucleoside kinases0Direct
Ribosomal protein L140Direct
Glutathione S-transferase (GST), N-terminal domain0Direct
Prefoldin0Direct
Histone deacetylase, HDAC0Direct
Ypt/Rab-GAP domain of gyp1p0Direct
Erythroid transcription factor GATA-10Direct
CorA soluble domain-like0Direct
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain0Direct
PR-1-like0Direct
p120GAP domain-like0Direct
Group II chaperonin (CCT, TRIC), ATPase domain0Direct
DNA ligase/mRNA capping enzyme postcatalytic domain0Direct
Ribosomal protein S130Direct
Gastric lipase0Direct
FAD-linked oxidases, N-terminal domain0Direct
Clathrin coat assembly domain0Direct
Cation efflux protein transmembrane domain-like0Direct
Heat shock protein 70kD (HSP70), peptide-binding domain0Direct
Eukaryotic type KH-domain (KH-domain type I)0Direct
Subtilases0Direct
Trehalose-6-phosphate synthase, OtsA0Direct
XPF/Rad1/Mus81 nuclease0Direct
Ubiquitin activating enzymes (UBA)0Direct
L30e/L7ae ribosomal proteins0Direct
Higher-molecular-weight phosphotyrosine protein phosphatases0Direct
Heat shock protein 70kD (HSP70), C-terminal subdomain0Direct
DnaQ-like 3'-5' exonuclease0Direct
Cytochrome P4500Direct
Ribosomal protein S40Direct
Ribokinase-like0Direct
UBA domain0Direct
beta-sandwich domain of Sec23/240Direct
Helical domain of Sec23/240Direct
Cyclin0Direct
Bacterial dinuclear zinc exopeptidases0Direct
PUA domain0Direct
Amidase signature (AS) enzymes0Direct
Cofilin-like0Direct
Cdc48 domain 2-like0Direct
Ubiquitin-related0Direct
Ran-binding domain0Direct
Single strand DNA-binding domain, SSB0Direct
Acetyl-CoA synthetase-like0Direct
PP2C-like0Direct
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain0Direct
Ribosomal protein L30p/L7e0Direct
CRAL/TRIO N-terminal domain0Direct
HMGL-like0Direct
Calponin-homology domain, CH-domain0Direct
PHD domain0Direct
Phosphoribosylpyrophosphate synthetase-like0Direct
La domain0Direct
Ribosomal protein S20Direct
NagB-like0Direct
Ribosomal protein L60Direct
MPP-like0Direct
FHA domain0Direct
Thiolase-related0Direct
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0Direct
HMG-box0Direct
SWIRM domain0Direct
Tetratricopeptide repeat (TPR)0Direct
SAM (sterile alpha motif) domain0Direct
Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain0Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0Direct
Deoxycytidylate deaminase-like0Direct
Myb/SANT domain0Direct
VHS domain0Direct
Zn-finger domain of Sec23/240Direct
Phoshoinositide 3-kinase (PI3K), catalytic domain0Direct
CBS-domain pair0Direct
ENTH domain0Direct
GAPDH-like0Direct
DNA gyrase/MutL, N-terminal domain0Direct
Isoprenyl diphosphate synthases0Direct
Dual specificity phosphatase-like0Direct
Class II glutamine amidotransferases0Direct
PDI-like0Direct
Multidomain cupredoxins0Direct
RuBisCo LSMT catalytic domain0Direct
Vacuolar sorting protein domain0Direct
Smc hinge domain0Direct
Sec7 domain0Direct
Transferrin receptor-like dimerisation domain0Direct
Lysophospholipase0Direct
Choline/Carnitine O-acyltransferase0Direct
Protein serine/threonine phosphatase0Direct
DnaJ/Hsp40 cysteine-rich domain0Direct
Undecaprenyl diphosphate synthase0Direct
FabD-like0Direct
BC N-terminal domain-like0Direct
RNB domain-like0Direct
L-aspartase/fumarase0Direct
HMA, heavy metal-associated domain0Direct
BCR-homology GTPase activation domain (BH-domain)0Direct
Tryptophan biosynthesis enzymes0Direct
Cap-Gly domain0Direct
Anticodon-binding domain of Class II aaRS0Direct
Armadillo repeat0Direct
6-phosphogluconate dehydrogenase-like, N-terminal domain0Direct
CCCH zinc finger0Direct
DNA-binding domain of Mlu1-box binding protein MBP10Direct
Aquaporin-like0Direct
PA domain0Direct
ABC transporter transmembrane region0Direct
Ribosomal protein L18 and S110Direct
Actin/HSP700Direct
WW domain0Direct
Class I aminoacyl-tRNA synthetases (RS), catalytic domain0Direct
Ribosomal protein S80Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Histidine acid phosphatase0Direct
C-terminal autoproteolytic domain of nucleoporin nup980Direct
CRAL/TRIO domain0Direct
DBL homology domain (DH-domain)0Direct
UBC-related0Direct
Class I aldolase0Direct
Group II chaperonin (CCT, TRIC), intermediate domain0Direct
Regulator of G-protein signaling, RGS0Direct
Proteasome subunits0Direct
N-type ATP pyrophosphatases0Direct
DNA repair protein MutS, domain I0Direct
Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain0Direct
ValRS/IleRS/LeuRS editing domain0Direct
HCP-like0Direct
Ras GEF0Direct
FAD-linked reductases, N-terminal domain0Direct
DNA gyrase/MutL, second domain0Direct
Reductases0Direct
TRAPP components0Direct
FtsH protease domain-like0Direct
Eps15 homology domain (EH domain)0Direct
Phosphoribulokinase/pantothenate kinase0Direct
GABA-aminotransferase-like0Direct
Ribosomal protein L130Direct
YAP1 redox domain0Direct
Bromodomain0Direct
Clathrin adaptor core protein0Direct
RING finger domain, C3HC40Direct
Folylpolyglutamate synthetase0Direct
C-terminal domain of ribosomal protein L20Direct
DJ-1/PfpI0Direct
Anticodon-binding domain0Direct
Phosphate binding protein-like0Direct
BC C-terminal domain-like0Direct
Class I alpha-1;2-mannosidase, catalytic domain0Direct
RNA-polymerase beta0Direct
tRNA-intron endonuclease catalytic domain-like0Direct
Magnesium transport protein CorA, transmembrane region0Direct
Thiamin biosynthesis kinases0Direct
Glucose 6-phosphate dehydrogenase-like0Direct
Tandem AAA-ATPase domain0.04864Inherited
Protein kinases, catalytic subunit0.16Inherited
Cold shock DNA-binding domain-like0.3394Inherited
Ankyrin repeat0.3606Inherited
Glutathione peroxidase-like0.6091Inherited
SH3-domain0.639Inherited
Thioltransferase0.683Inherited
FYVE, a phosphatidylinositol-3-phosphate binding domain0.7823Inherited
5' to 3' exonuclease catalytic domain0.7823Inherited
5' to 3' exonuclease, C-terminal subdomain0.7823Inherited
Inositol polyphosphate 5-phosphatase (IPP5)0.8217Inherited
G proteins0.8866Inherited
Cyclophilin (peptidylprolyl isomerase)0.9337Inherited
Ubiquitin carboxyl-terminal hydrolase, UCH0.9392Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
Plot tree as:   Download Newick format tree:
(show help)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Trimeric LpxA-like enzymes0Direct
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD0Direct
LuxS/MPP-like metallohydrolase0Direct
Kelch motif0Direct
Chaperone J-domain0Direct
Ribosomal protein L130Direct
RNI-like0Direct
Tubulin nucleotide-binding domain-like0Direct
YjgF-like0Direct
Acetyl-CoA synthetase-like0Direct
Cdc48 domain 2-like0Direct
Ribosomal protein L140Direct
Nucleoporin domain0Direct
Ribosomal protein L60Direct
DNA ligase/mRNA capping enzyme, catalytic domain0Direct
DNA-binding domain of Mlu1-box binding protein MBP10Direct
Protein prenylyltransferase0Direct
PAP/OAS1 substrate-binding domain0Direct
Phospholipase D/nuclease0Direct
4'-phosphopantetheinyl transferase0Direct
FMN-binding split barrel0Direct
DNA repair protein MutS, domain I0Direct
Tryptophan synthase beta subunit-like PLP-dependent enzymes0Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase0Direct
Ribonuclease PH domain 2-like0Direct
L30e-like0Direct
post-HMGL domain-like0Direct
FabD/lysophospholipase-like0Direct
Glutamine synthetase/guanido kinase0Direct
Ribulose-phoshate binding barrel0Direct
ArfGap/RecO-like zinc finger0Direct
C-terminal, gelsolin-like domain of Sec23/240Direct
HLH, helix-loop-helix DNA-binding domain0Direct
Sec63 N-terminal domain-like0Direct
Arginase/deacetylase0Direct
FAD-linked oxidoreductase0Direct
HIT/MYND zinc finger-like0Direct
Ribosomal L11/L12e N-terminal domain0Direct
RBP11-like subunits of RNA polymerase0Direct
YAP1 redox domain0Direct
Thiolase-like0Direct
Mitochondrial cytochrome c oxidase subunit IV0Direct
Clavaminate synthase-like0Direct
Ribonuclease H-like0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
SET domain0Direct
MurD-like peptide ligases, catalytic domain0Direct
PP2C-like0Direct
PreATP-grasp domain0Direct
beta-sandwich domain of Sec23/240Direct
TK C-terminal domain-like0Direct
DNA repair protein MutS, domain II0Direct
BRCT domain0Direct
Ribosomal protein S80Direct
HMG-box0Direct
FtsH protease domain-like0Direct
Glucocorticoid receptor-like (DNA-binding domain)0Direct
The spindle assembly checkpoint protein mad20Direct
Translational machinery components0Direct
Ligand-binding domain in the NO signalling and Golgi transport0Direct
Ribosomal protein S20Direct
PriA/YqbF domain0Direct
alpha/beta knot0Direct
Mss4-like0Direct
Supernatant protein factor (SPF), C-terminal domain0Direct
L-aspartase-like0Direct
Ribosomal protein L11, C-terminal domain0Direct
Ribosomal protein L10-like0Direct
Fe,Mn superoxide dismutase (SOD), C-terminal domain0Direct
Restriction endonuclease-like0Direct
post-AAA+ oligomerization domain-like0Direct
Transferrin receptor-like dimerisation domain0Direct
Inosine monophosphate dehydrogenase (IMPDH)0Direct
Smc hinge domain0Direct
HCP-like0Direct
Ribosomal protein L220Direct
Single hybrid motif0Direct
FAD/NAD-linked reductases, dimerisation (C-terminal) domain0Direct
SAICAR synthase-like0Direct
Acid proteases0Direct
Terpenoid synthases0Direct
YVTN repeat-like/Quinoprotein amine dehydrogenase0Direct
Metallo-hydrolase/oxidoreductase0Direct
Actin depolymerizing proteins0Direct
S13-like H2TH domain0Direct
Fumarate reductase respiratory complex transmembrane subunits0Direct
EF-G C-terminal domain-like0Direct
RmlC-like cupins0Direct
KA1-like0Direct
CBS-domain pair0Direct
POZ domain0Direct
SAP domain0Direct
Heat shock protein 70kD (HSP70), C-terminal subdomain0Direct
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0Direct
GHMP Kinase, C-terminal domain0Direct
CCCH zinc finger0Direct
C-terminal autoproteolytic domain of nucleoporin nup980Direct
HSP20-like chaperones0Direct
DNA repair protein MutS, domain III0Direct
Ras GEF0Direct
Cation efflux protein transmembrane domain-like0Direct
Bromodomain0Direct
Family A G protein-coupled receptor-like0Direct
ThrRS/AlaRS common domain0Direct
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0Direct
Ribosomal protein L30p/L7e0Direct
DNA/RNA polymerases0Direct
R3H domain0Direct
Nucleotidylyl transferase0Direct
PR-1-like0Direct
SNARE-like0Direct
HRDC-like0Direct
GST C-terminal domain-like0Direct
Magnesium transport protein CorA, transmembrane region0Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0Direct
Radical SAM enzymes0Direct
PA domain0Direct
Rudiment single hybrid motif0Direct
F1F0 ATP synthase subunit C0Direct
Cytochrome P4500Direct
JAB1/MPN domain0Direct
NTF2-like0Direct
Nop domain0Direct
Tubulin C-terminal domain-like0Direct
GAT-like domain0Direct
CorA soluble domain-like0Direct
MurD-like peptide ligases, peptide-binding domain0Direct
LexA/Signal peptidase0Direct
Zn-binding ribosomal proteins0Direct
Metallo-dependent hydrolases0Direct
Cytochrome c0Direct
Aconitase iron-sulfur domain0Direct
Carbon-nitrogen hydrolase0Direct
Carbohydrate phosphatase0Direct
Zinc domain conserved in yeast copper-regulated transcription factors0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
vWA-like0Direct
CRAL/TRIO domain0Direct
Subtilisin-like0Direct
Chromo domain-like0Direct
Prefoldin0Direct
VPS9 domain0Direct
Aldolase0Direct
Cupredoxins0Direct
Activating enzymes of the ubiquitin-like proteins0Direct
PUA domain-like0Direct
cAMP-binding domain-like0Direct
Six-hairpin glycosidases0Direct
CoA-dependent acyltransferases0Direct
Cap-Gly domain0Direct
Sec7 domain0Direct
Class II aaRS ABD-related0Direct
DNA-glycosylase0Direct
eIF1-like0Direct
Aquaporin-like0Direct
Alkaline phosphatase-like0Direct
tRNA-intron endonuclease catalytic domain-like0Direct
HSP40/DnaJ peptide-binding domain0Direct
Helical domain of Sec23/240Direct
DBL homology domain (DH-domain)0Direct
Nucleotide-binding domain0Direct
ValRS/IleRS/LeuRS editing domain0Direct
Amidase signature (AS) enzymes0Direct
HMA, heavy metal-associated domain0Direct
Carbamate kinase-like0Direct
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain0Direct
Methylglyoxal synthase-like0Direct
HIT-like0Direct
RNase III domain-like0Direct
Clathrin adaptor appendage domain0Direct
Heat shock protein 70kD (HSP70), peptide-binding domain0Direct
Cytidine deaminase-like0Direct
Seven-hairpin glycosidases0Direct
Ribokinase-like0Direct
Glutathione synthetase ATP-binding domain-like0Direct
Terpenoid cyclases/Protein prenyltransferases0Direct
Regulator of G-protein signaling, RGS0Direct
Phosphoenolpyruvate/pyruvate domain0Direct
CheY-like0Direct
Ferritin-like0Direct
Retrovirus zinc finger-like domains0Direct
Alpha-L RNA-binding motif0Direct
Adenine nucleotide alpha hydrolases-like0Direct
CRAL/TRIO N-terminal domain0Direct
Glycoside hydrolase/deacetylase0Direct
GYF domain0Direct
PYP-like sensor domain (PAS domain)0Direct
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain0Direct
GINS helical bundle-like0Direct
Cysteine alpha-hairpin motif0Direct
Undecaprenyl diphosphate synthase0Direct
Eukaryotic type KH-domain (KH-domain type I)0Direct
LeuD/IlvD-like0Direct
ALDH-like0Direct
Calponin-homology domain, CH-domain0Direct
Zn-finger domain of Sec23/240Direct
WW domain0Direct
Tricorn protease domain 20Direct
Endosomal sorting complex assembly domain0Direct
EPT/RTPC-like0Direct
DnaJ/Hsp40 cysteine-rich domain0Direct
Ypt/Rab-GAP domain of gyp1p0Direct
HD-domain/PDEase-like0Direct
Zn-dependent exopeptidases0Direct
dsRNA-binding domain-like0Direct
Protein kinase-like (PK-like)0.1295Inherited
ARM repeat0.1749Inherited
Nucleic acid-binding proteins0.2215Inherited
"Winged helix" DNA-binding domain0.2797Inherited
Class II aaRS and biotin synthetases0.3106Inherited
Ankyrin repeat0.3472Inherited
Translation proteins SH3-like domain0.3917Inherited
ENTH/VHS domain0.4364Inherited
P-loop containing nucleoside triphosphate hydrolases0.5395Inherited
C2 domain (Calcium/lipid-binding domain, CaLB)0.5477Inherited
GroEL apical domain-like0.5792Inherited
SH3-domain0.6262Inherited
Histone-fold0.6262Inherited
Nucleotidyltransferase0.7505Inherited
5' to 3' exonuclease, C-terminal subdomain0.7869Inherited
Cyclophilin-like0.8993Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
54211,55060
  • 54211 - Ribosomal protein S5 domain 2-like
  • 55060 - GHMP Kinase, C-terminal domain
  • 0Direct
    53613,48613
  • 53613 - Ribokinase-like
  • 48613 - Heme oxygenase-like
  • 0Direct
    51905,56425
  • 51905 - FAD/NAD(P)-binding domain
  • 56425 - Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain
  • 0Direct
    52518,52518
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 0Direct
    47923,47923
  • 47923 - Ypt/Rab-GAP domain of gyp1p
  • 47923 - Ypt/Rab-GAP domain of gyp1p
  • 0Direct
    48334,52540
  • 48334 - DNA repair protein MutS, domain III
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    53901,53901
  • 53901 - Thiolase-like
  • 53901 - Thiolase-like
  • 0Direct
    56059,51246
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 51246 - Rudiment single hybrid motif
  • 0Direct
    52833,47616
  • 52833 - Thioredoxin-like
  • 47616 - GST C-terminal domain-like
  • 0Direct
    143865,144083
  • 143865 - CorA soluble domain-like
  • 144083 - Magnesium transport protein CorA, transmembrane region
  • 0Direct
    46785,46785
  • 46785 - "Winged helix" DNA-binding domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    57756,57756
  • 57756 - Retrovirus zinc finger-like domains
  • 57756 - Retrovirus zinc finger-like domains
  • 0Direct
    53067,53067
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 0Direct
    52518,52922
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 52922 - TK C-terminal domain-like
  • 0Direct
    51905,51905
  • 51905 - FAD/NAD(P)-binding domain
  • 51905 - FAD/NAD(P)-binding domain
  • 0Direct
    53732,52016
  • 53732 - Aconitase iron-sulfur domain
  • 52016 - LeuD/IlvD-like
  • 0Direct
    52025,53187
  • 52025 - PA domain
  • 53187 - Zn-dependent exopeptidases
  • 0Direct
    57850,52540
  • 57850 - RING/U-box
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    50615,52540
  • 50615 - N-terminal domain of alpha and beta subunits of F1 ATP synthase
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    48371,48371
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 0Direct
    54631,54631
  • 54631 - CBS-domain pair
  • 54631 - CBS-domain pair
  • 0Direct
    49493,49493
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 0Direct
    54236,57829
  • 54236 - Ubiquitin-like
  • 57829 - Zn-binding ribosomal proteins
  • 0Direct
    -9,52954
  • -9 - PDB
  • 52954 - Class II aaRS ABD-related
  • 0Direct
    52540,140990
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 140990 - FtsH protease domain-like
  • 0Direct
    52440,56059
  • 52440 - PreATP-grasp domain
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 0Direct
    56053,56053
  • 56053 - Ribosomal protein L6
  • 56053 - Ribosomal protein L6
  • 0Direct
    50978,50978
  • 50978 - WD40 repeat-like
  • 50978 - WD40 repeat-like
  • 0Direct
    53756,56784
  • 53756 - UDP-Glycosyltransferase/glycogen phosphorylase
  • 56784 - HAD-like
  • 0Direct
    90229,90229
  • 90229 - CCCH zinc finger
  • 90229 - CCCH zinc finger
  • 0Direct
    57938,49493
  • 57938 - DnaJ/Hsp40 cysteine-rich domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 0Direct
    54631,51412
  • 54631 - CBS-domain pair
  • 51412 - Inosine monophosphate dehydrogenase (IMPDH)
  • 0Direct
    52540,47917
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase
  • 0Direct
    48464,89009
  • 48464 - ENTH/VHS domain
  • 89009 - GAT-like domain
  • 0Direct
    52777,52777
  • 52777 - CoA-dependent acyltransferases
  • 52777 - CoA-dependent acyltransferases
  • 0Direct
    53623,53244
  • 53623 - MurD-like peptide ligases, catalytic domain
  • 53244 - MurD-like peptide ligases, peptide-binding domain
  • 0Direct
    50447,54980
  • 50447 - Translation proteins
  • 54980 - EF-G C-terminal domain-like
  • 0Direct
    48452,48452
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 0Direct
    53187,47672
  • 53187 - Zn-dependent exopeptidases
  • 47672 - Transferrin receptor-like dimerisation domain
  • 0Direct
    55681,52954
  • 55681 - Class II aaRS and biotin synthetases
  • 52954 - Class II aaRS ABD-related
  • 0Direct
    51569,89000
  • 51569 - Aldolase
  • 89000 - post-HMGL domain-like
  • 0Direct
    82919,53300
  • 82919 - Zn-finger domain of Sec23/24
  • 53300 - vWA-like
  • 0Direct
    103657,50729
  • 103657 - BAR/IMD domain-like
  • 50729 - PH domain-like
  • 0Direct
    49503,49503
  • 49503 - Cupredoxins
  • 49503 - Cupredoxins
  • 0Direct
    50677,52374
  • 50677 - ValRS/IleRS/LeuRS editing domain
  • 52374 - Nucleotidylyl transferase
  • 0Direct
    56235,52402
  • 56235 - N-terminal nucleophile aminohydrolases (Ntn hydrolases)
  • 52402 - Adenine nucleotide alpha hydrolases-like
  • 0Direct
    51905,55424
  • 51905 - FAD/NAD(P)-binding domain
  • 55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain
  • 0Direct
    50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0Direct
    53067,100920
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 0Direct
    54211,54980
  • 54211 - Ribosomal protein S5 domain 2-like
  • 54980 - EF-G C-terminal domain-like
  • 0Direct
    56091,50249
  • 56091 - DNA ligase/mRNA capping enzyme, catalytic domain
  • 50249 - Nucleic acid-binding proteins
  • 0Direct
    52540,90123
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 90123 - ABC transporter transmembrane region
  • 0Direct
    81811,82754
  • 81811 - Helical domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0Direct
    53098,56672
  • 53098 - Ribonuclease H-like
  • 56672 - DNA/RNA polymerases
  • 0Direct
    54791,54791
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 0Direct
    46565,57938
  • 46565 - Chaperone J-domain
  • 57938 - DnaJ/Hsp40 cysteine-rich domain
  • 0Direct
    46689,46689
  • 46689 - Homeodomain-like
  • 46689 - Homeodomain-like
  • 0Direct
    52490,55307
  • 52490 - Tubulin nucleotide-binding domain-like
  • 55307 - Tubulin C-terminal domain-like
  • 0Direct
    55874,54211
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0Direct
    54747,46906
  • 54747 - Ribosomal L11/L12e N-terminal domain
  • 46906 - Ribosomal protein L11, C-terminal domain
  • 0Direct
    46938,52087
  • 46938 - CRAL/TRIO N-terminal domain
  • 52087 - CRAL/TRIO domain
  • 0Direct
    52058,52058
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 0Direct
    53150,48334
  • 53150 - DNA repair protein MutS, domain II
  • 48334 - DNA repair protein MutS, domain III
  • 0Direct
    54980,54211
  • 54980 - EF-G C-terminal domain-like
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0Direct
    56024,56024
  • 56024 - Phospholipase D/nuclease
  • 56024 - Phospholipase D/nuclease
  • 0Direct
    48371,-7
  • 48371 - ARM repeat
  • -7 - CATH
  • 0Direct
    54897,52743
  • 54897 - Protease propeptides/inhibitors
  • 52743 - Subtilisin-like
  • 0Direct
    49879,56112
  • 49879 - SMAD/FHA domain
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    52540,48019
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 48019 - post-AAA+ oligomerization domain-like
  • 0Direct
    -7,52540
  • -7 - CATH
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    48371,52540
  • 48371 - ARM repeat
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    54211,55666
  • 54211 - Ribosomal protein S5 domain 2-like
  • 55666 - Ribonuclease PH domain 2-like
  • 0Direct
    52374,47323
  • 52374 - Nucleotidylyl transferase
  • 47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
  • 0Direct
    52540,53254
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 53254 - Phosphoglycerate mutase-like
  • 0Direct
    81301,81631
  • 81301 - Nucleotidyltransferase
  • 81631 - PAP/OAS1 substrate-binding domain
  • 0Direct
    81995,82919
  • 81995 - beta-sandwich domain of Sec23/24
  • 82919 - Zn-finger domain of Sec23/24
  • 0Direct
    81333,81333
  • 81333 - F1F0 ATP synthase subunit C
  • 81333 - F1F0 ATP synthase subunit C
  • 0Direct
    52833,52833
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 0Direct
    50249,50104
  • 50249 - Nucleic acid-binding proteins
  • 50104 - Translation proteins SH3-like domain
  • 0Direct
    63380,52343
  • 63380 - Riboflavin synthase domain-like
  • 52343 - Ferredoxin reductase-like, C-terminal NADP-linked domain
  • 0Direct
    63411,63411
  • 63411 - LuxS/MPP-like metallohydrolase
  • 63411 - LuxS/MPP-like metallohydrolase
  • 0Direct
    50249,50249
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 0Direct
    49562,49562
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0Direct
    -9,-9
  • -9 - PDB
  • -9 - PDB
  • 0Direct
    50249,55681
  • 50249 - Nucleic acid-binding proteins
  • 55681 - Class II aaRS and biotin synthetases
  • 0Direct
    51735,55347
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 55347 - Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain
  • 0Direct
    100920,100934
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
  • 0Direct
    52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.2545Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    52540,90123,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    90123,52540,90123
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 90123 - ABC transporter transmembrane region
  • 0Direct
    52025,53187,47672
  • 52025 - PA domain
  • 53187 - Zn-dependent exopeptidases
  • 47672 - Transferrin receptor-like dimerisation domain
  • 0Direct
    52540,50447,54980
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 54980 - EF-G C-terminal domain-like
  • 0Direct
    81995,82919,53300
  • 81995 - beta-sandwich domain of Sec23/24
  • 82919 - Zn-finger domain of Sec23/24
  • 53300 - vWA-like
  • 0Direct
    50615,52540,47917
  • 50615 - N-terminal domain of alpha and beta subunits of F1 ATP synthase
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase
  • 0Direct
    48452,48452,48452
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 0Direct
    46565,57938,49493
  • 46565 - Chaperone J-domain
  • 57938 - DnaJ/Hsp40 cysteine-rich domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 0Direct
    53150,48334,52540
  • 53150 - DNA repair protein MutS, domain II
  • 48334 - DNA repair protein MutS, domain III
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    48371,48371,48371
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 0Direct
    53067,53067,100920
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 0Direct
    57756,57756,57756
  • 57756 - Retrovirus zinc finger-like domains
  • 57756 - Retrovirus zinc finger-like domains
  • 57756 - Retrovirus zinc finger-like domains
  • 0Direct
    53067,100920,100934
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
  • 0Direct
    50447,54980,54211
  • 50447 - Translation proteins
  • 54980 - EF-G C-terminal domain-like
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0Direct
    49562,49562,49562
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0Direct
    49503,49503,49503
  • 49503 - Cupredoxins
  • 49503 - Cupredoxins
  • 49503 - Cupredoxins
  • 0Direct
    57938,49493,49493
  • 57938 - DnaJ/Hsp40 cysteine-rich domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 0Direct
    48371,52540,52540
  • 48371 - ARM repeat
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    52440,56059,51246
  • 52440 - PreATP-grasp domain
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 51246 - Rudiment single hybrid motif
  • 0Direct
    54980,54211,54980
  • 54980 - EF-G C-terminal domain-like
  • 54211 - Ribosomal protein S5 domain 2-like
  • 54980 - EF-G C-terminal domain-like
  • 0Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)