SUPERFAMILY 1.75 HMM library and genome assignments server

Yeast Phenotype (YP): cellular processes

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Root: YP Hierarchy (yeast phenotype from Ascomycete phenotype ontology)

Shortest distance to current term (+ for parents, - for children) YP term [YP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ 1:   observable [APO:0000017] <7>
0:   cellular processes [APO:0000066] <6>(203|206) (203|73|16)
- 1:   stress resistance [APO:0000080] <10>(178|177) (178|65|15)
- 1:   chromosome/plasmid maintenance [APO:0000143] <8>(9|11) (9|1|0)
- 1:   intracellular transport [APO:0000073] <6>(7|5) (8|0|0)
- 1:   mitotic cell cycle [APO:0000072] <5>(10|10) (10|1|0)
- 1:   cell death [APO:0000312] <4>(1|2) (1|0|0)
- 1:   prion state [APO:0000274] <3>(0|0) (0|0|0)


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Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Tim10-like0Direct
Cytidine deaminase-like0Direct
ArfGap/RecO-like zinc finger0Direct
FMN-binding split barrel0Direct
RNase III domain-like0Direct
Rudiment single hybrid motif0Direct
Cation efflux protein transmembrane domain-like0Direct
Ribosomal protein S80Direct
Zn-dependent exopeptidases0Direct
EPT/RTPC-like0Direct
PR-1-like0Direct
Subtilisin-like0Direct
TK C-terminal domain-like0Direct
LexA/Signal peptidase0Direct
C-terminal autoproteolytic domain of nucleoporin nup980Direct
YAP1 redox domain0Direct
CRAL/TRIO N-terminal domain0Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0Direct
Inosine monophosphate dehydrogenase (IMPDH)0Direct
The spindle assembly checkpoint protein mad20Direct
WW domain0Direct
cAMP-binding domain-like0Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase0Direct
Supernatant protein factor (SPF), C-terminal domain0Direct
Ribosomal protein L140Direct
HIT-like0Direct
Clathrin adaptor appendage domain0Direct
Helical domain of Sec23/240Direct
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain0Direct
L-aspartase-like0Direct
LuxS/MPP-like metallohydrolase0Direct
Oxysterol-binding protein-like0Direct
POZ domain0Direct
Nucleotidylyl transferase0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
SAICAR synthase-like0Direct
Metallo-hydrolase/oxidoreductase0Direct
Carbohydrate phosphatase0Direct
CBS-domain pair0Direct
DBL homology domain (DH-domain)0Direct
Ligand-binding domain in the NO signalling and Golgi transport0Direct
SAP domain0Direct
Prefoldin0Direct
Aconitase iron-sulfur domain0Direct
Glutathione synthetase ATP-binding domain-like0Direct
FabD/lysophospholipase-like0Direct
Undecaprenyl diphosphate synthase0Direct
PP2C-like0Direct
Glycoside hydrolase/deacetylase0Direct
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0Direct
Cytochrome P4500Direct
Bromodomain0Direct
4'-phosphopantetheinyl transferase0Direct
HCP-like0Direct
DNA ligase/mRNA capping enzyme, catalytic domain0Direct
Trimeric LpxA-like enzymes0Direct
CRAL/TRIO domain0Direct
Mitochondrial cytochrome c oxidase subunit IV0Direct
HLH, helix-loop-helix DNA-binding domain0Direct
Ferritin-like0Direct
PriA/YqbF domain0Direct
Endosomal sorting complex assembly domain0Direct
Glucocorticoid receptor-like (DNA-binding domain)0Direct
Ribokinase-like0Direct
DNA/RNA polymerases0Direct
HD-domain/PDEase-like0Direct
HMG-box0Direct
ValRS/IleRS/LeuRS editing domain0Direct
HSP20-like chaperones0Direct
HRDC-like0Direct
Chaperone J-domain0Direct
DNA repair protein MutS, domain II0Direct
GYF domain0Direct
Methylglyoxal synthase-like0Direct
Zn-binding ribosomal proteins0Direct
Terpenoid synthases0Direct
vWA-like0Direct
VPS9 domain0Direct
KA1-like0Direct
Heat shock protein 70kD (HSP70), C-terminal subdomain0Direct
Alpha-L RNA-binding motif0Direct
Magnesium transport protein CorA, transmembrane region0Direct
DNA repair protein MutS, domain I0Direct
UBC-like0Direct
Tubulin nucleotide-binding domain-like0Direct
Protein prenylyltransferase0Direct
Fe,Mn superoxide dismutase (SOD), C-terminal domain0Direct
ALDH-like0Direct
Glutamine synthetase/guanido kinase0Direct
Class II aaRS ABD-related0Direct
L30e-like0Direct
Seven-hairpin glycosidases0Direct
Clavaminate synthase-like0Direct
DNA-glycosylase0Direct
HIT/MYND zinc finger-like0Direct
Retrovirus zinc finger-like domains0Direct
Smc hinge domain0Direct
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0Direct
Ribosomal protein L10-like0Direct
Ribulose-phoshate binding barrel0Direct
Tricorn protease domain 20Direct
Ras GEF0Direct
Terpenoid cyclases/Protein prenyltransferases0Direct
Zinc domain conserved in yeast copper-regulated transcription factors0Direct
Chromo domain-like0Direct
Sec7 domain0Direct
beta-sandwich domain of Sec23/240Direct
Family A G protein-coupled receptor-like0Direct
Nucleoporin domain0Direct
HMA, heavy metal-associated domain0Direct
RmlC-like cupins0Direct
Radical SAM enzymes0Direct
YjgF-like0Direct
FAD-linked oxidases, C-terminal domain0Direct
Carbon-nitrogen hydrolase0Direct
Nucleotide-binding domain0Direct
PA domain0Direct
CorA soluble domain-like0Direct
GST C-terminal domain-like0Direct
PYP-like sensor domain (PAS domain)0Direct
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0Direct
Restriction endonuclease-like0Direct
FAD-binding/transporter-associated domain-like0Direct
dsRNA-binding domain-like0Direct
Tubulin C-terminal domain-like0Direct
Ribosomal protein L130Direct
Heat shock protein 70kD (HSP70), peptide-binding domain0Direct
Zn-finger domain of Sec23/240Direct
C-terminal, gelsolin-like domain of Sec23/240Direct
Carbamate kinase-like0Direct
Single hybrid motif0Direct
RNI-like0Direct
DNA repair protein MutS, domain III0Direct
AMPKBI-like0Direct
Transferrin receptor-like dimerisation domain0Direct
GAT-like domain0Direct
MurD-like peptide ligases, peptide-binding domain0Direct
Ribosomal protein L30p/L7e0Direct
Ribosomal protein L60Direct
ThrRS/AlaRS common domain0Direct
eIF1-like0Direct
RBP11-like subunits of RNA polymerase0Direct
Alkaline phosphatase-like0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
FAD/NAD-linked reductases, dimerisation (C-terminal) domain0Direct
Ribosomal L11/L12e N-terminal domain0Direct
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD0Direct
Nop domain0Direct
PAP/OAS1 substrate-binding domain0Direct
HSP40/DnaJ peptide-binding domain0Direct
S13-like H2TH domain0Direct
Phospholipase D/nuclease0Direct
SNARE-like0Direct
post-HMGL domain-like0Direct
Ribosomal proteins L15p and L18e0Direct
GINS helical bundle-like0Direct
Amidase signature (AS) enzymes0Direct
SRF-like0Direct
CheY-like0Direct
FtsH protease domain-like0Direct
Translational machinery components0Direct
F1F0 ATP synthase subunit C0Direct
MurD-like peptide ligases, catalytic domain0Direct
PUA domain-like0Direct
Six-hairpin glycosidases0Direct
PreATP-grasp domain0Direct
Aldolase0Direct
DnaJ/Hsp40 cysteine-rich domain0Direct
Ypt/Rab-GAP domain of gyp1p0Direct
Cdc48 domain 2-like0Direct
Cysteine alpha-hairpin motif0Direct
Thiolase-like0Direct
Cap-Gly domain0Direct
Arginase/deacetylase0Direct
Kelch motif0Direct
R3H domain0Direct
Adenine nucleotide alpha hydrolases-like0Direct
alpha/beta knot0Direct
Cytochrome c0Direct
YVTN repeat-like/Quinoprotein amine dehydrogenase0Direct
Sec63 N-terminal domain-like0Direct
tRNA-intron endonuclease catalytic domain-like0Direct
CCCH zinc finger0Direct
NTF2-like0Direct
Ribosomal protein L11, C-terminal domain0Direct
DNA-binding domain of Mlu1-box binding protein MBP10Direct
Actin depolymerizing proteins0Direct
BRCT domain0Direct
Class II aaRS and biotin synthetases0.237Inherited
Ankyrin repeat0.2723Inherited
Nucleic acid-binding proteins0.3099Inherited
Class I glutamine amidotransferase-like0.3634Inherited
ENTH/VHS domain0.3634Inherited
"Winged helix" DNA-binding domain0.3874Inherited
Protein kinase-like (PK-like)0.4752Inherited
C2 domain (Calcium/lipid-binding domain, CaLB)0.478Inherited
ARM repeat0.5113Inherited
SH3-domain0.5283Inherited
Histone-fold0.5283Inherited
P-loop containing nucleoside triphosphate hydrolases0.629Inherited
post-AAA+ oligomerization domain-like0.7057Inherited
5' to 3' exonuclease, C-terminal subdomain0.7479Inherited
Cyclophilin-like0.8595Inherited


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Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Ribosomal protein L130Direct
Oxysterol-binding protein0Direct
DnaQ-like 3'-5' exonuclease0Direct
Ribokinase-like0Direct
SAP domain0Direct
Bacterial dinuclear zinc exopeptidases0Direct
Armadillo repeat0Direct
Cyclin0Direct
WW domain0Direct
Clathrin adaptor core protein0Direct
Glutathione S-transferase (GST), N-terminal domain0Direct
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain0Direct
FabD-like0Direct
GAPDH-like0Direct
Ribosomal protein L14e0Direct
Ribosomal proteins L15p and L18e0Direct
VPS9 domain0Direct
Inositol monophosphatase/fructose-1,6-bisphosphatase-like0Direct
Ras GEF0Direct
Protein prenyltransferases0Direct
Forkhead DNA-binding domain0Direct
beta-sandwich domain of Sec23/240Direct
Ribosomal L11/L12e N-terminal domain0Direct
HLH, helix-loop-helix DNA-binding domain0Direct
HSP40/DnaJ peptide-binding domain0Direct
HMGL-like0Direct
Vacuolar sorting protein domain0Direct
C-terminal domain of ribosomal protein L20Direct
VHS domain0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
FAD/NAD-linked reductases, N-terminal and central domains0Direct
Class II glutamine amidotransferases0Direct
Histidine acid phosphatase0Direct
Ribosomal protein S80Direct
PR-1-like0Direct
Ribosomal protein L140Direct
Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain0Direct
YAP1 redox domain0Direct
Ubiquitin-related0Direct
Ribosomal protein S130Direct
Erythroid transcription factor GATA-10Direct
Lysophospholipase0Direct
Inosine monophosphate dehydrogenase (IMPDH)0Direct
C-terminal autoproteolytic domain of nucleoporin nup980Direct
C-terminal, gelsolin-like domain of Sec23/240Direct
FAD-linked oxidases, N-terminal domain0Direct
RecA protein-like (ATPase-domain)0Direct
DJ-1/PfpI0Direct
Trunk domain of Sec23/240Direct
DNA gyrase/MutL, N-terminal domain0Direct
Hexokinase0Direct
UBA domain0Direct
Thiamin biosynthesis kinases0Direct
Single strand DNA-binding domain, SSB0Direct
Reductases0Direct
GYF domain0Direct
MIF4G domain-like0Direct
Undecaprenyl diphosphate synthase0Direct
RING finger domain, C3HC40Direct
L30e/L7ae ribosomal proteins0Direct
DNA ligase/mRNA capping enzyme postcatalytic domain0Direct
Retrovirus zinc finger-like domains0Direct
MPP-like0Direct
Isoprenyl diphosphate synthases0Direct
HAT/Suf repeat0Direct
ALDH-like0Direct
DNA repair protein MutS, domain I0Direct
UBC-related0Direct
Aconitase iron-sulfur domain0Direct
Heat shock protein 70kD (HSP70), C-terminal subdomain0Direct
Class I alpha-1;2-mannosidase, catalytic domain0Direct
Pyk2-associated protein beta ARF-GAP domain0Direct
PHD domain0Direct
Ribosomal protein L11, C-terminal domain0Direct
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD0Direct
Zinc domain conserved in yeast copper-regulated transcription factors0Direct
LeuD-like0Direct
Bacteriorhodopsin-like0Direct
SAM (sterile alpha motif) domain0Direct
Histone deacetylase, HDAC0Direct
Proteasome subunits0Direct
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0Direct
Trehalose-6-phosphate synthase, OtsA0Direct
NTF2-like0Direct
Cofilin-like0Direct
AMPKBI-like0Direct
CBS-domain pair0Direct
PP2C-like0Direct
PyrH-like0Direct
SWIRM domain0Direct
Glutathione S-transferase (GST), C-terminal domain0Direct
Ribosomal protein L18 and S110Direct
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain0Direct
DNA-binding domain of Mlu1-box binding protein MBP10Direct
tRNA-intron endonuclease catalytic domain-like0Direct
Tubulin, C-terminal domain0Direct
Clathrin coat assembly domain0Direct
Prefoldin0Direct
Amidase signature (AS) enzymes0Direct
Cdc48 domain 2-like0Direct
TRAPP components0Direct
Biotinyl/lipoyl-carrier proteins and domains0Direct
Class I aldolase0Direct
Tetratricopeptide repeat (TPR)0Direct
Thiolase-related0Direct
Serine carboxypeptidase-like0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
L-aspartase/fumarase0Direct
Anticodon-binding domain of Class II aaRS0Direct
Smc hinge domain0Direct
PDI-like0Direct
Transferrin receptor-like dimerisation domain0Direct
Zn-finger domain of Sec23/240Direct
Ribosomal protein S40Direct
DNA polymerase III clamp loader subunits, C-terminal domain0Direct
HMG-box0Direct
UDP-glucose pyrophosphorylase0Direct
Nucleosome core histones0Direct
Glycosyl hydrolases family 160Direct
Myb/SANT domain0Direct
RNA-polymerase beta-prime0Direct
Cytochrome P4500Direct
FAD/NAD-linked reductases, dimerisation (C-terminal) domain0Direct
BC C-terminal domain-like0Direct
Pseudouridine synthase I TruA0Direct
DBL homology domain (DH-domain)0Direct
Subtilases0Direct
Ferredoxin reductase FAD-binding domain-like0Direct
Eps15 homology domain (EH domain)0Direct
La domain0Direct
Magnesium transport protein CorA, transmembrane region0Direct
Ran-binding domain0Direct
Phosphoribulokinase/pantothenate kinase0Direct
BC N-terminal domain-like0Direct
DnaJ/Hsp40 cysteine-rich domain0Direct
Cation efflux protein transmembrane domain-like0Direct
RNB domain-like0Direct
PA domain0Direct
ValRS/IleRS/LeuRS editing domain0Direct
Class I aminoacyl-tRNA synthetases (RS), catalytic domain0Direct
Sec7 domain0Direct
DNA gyrase/MutL, second domain0Direct
PUA domain0Direct
CRAL/TRIO domain0Direct
Cap-Gly domain0Direct
YjgF/L-PSP0Direct
eIF1-like0Direct
DNA repair protein MutS, domain III0Direct
Higher-molecular-weight phosphotyrosine protein phosphatases0Direct
N-type ATP pyrophosphatases0Direct
Nucleotide and nucleoside kinases0Direct
Gastric lipase0Direct
Deoxycytidylate deaminase-like0Direct
DNA polymerase I0Direct
Tryptophan biosynthesis enzymes0Direct
Anticodon-binding domain0Direct
Adenosine/AMP deaminase0Direct
FtsH protease domain-like0Direct
CRAL/TRIO N-terminal domain0Direct
BCR-homology GTPase activation domain (BH-domain)0Direct
Tubulin, GTPase domain0Direct
Nop domain0Direct
ENTH domain0Direct
Tim10/DDP0Direct
Protein serine/threonine phosphatase0Direct
Bromodomain0Direct
6-phosphogluconate dehydrogenase-like, N-terminal domain0Direct
Pumilio repeat0Direct
HMA, heavy metal-associated domain0Direct
Heat shock protein 70kD (HSP70), peptide-binding domain0Direct
Fe,Mn superoxide dismutase (SOD), C-terminal domain0Direct
FAD-linked reductases, N-terminal domain0Direct
p120GAP domain-like0Direct
GABA-aminotransferase-like0Direct
SRF-like0Direct
RNA methyltransferase FtsJ0Direct
Folylpolyglutamate synthetase0Direct
Ribosomal protein L30p/L7e0Direct
Phosphoribosylpyrophosphate synthetase-like0Direct
RNA-polymerase beta0Direct
Phosphate binding protein-like0Direct
DNA replication initiator (cdc21/cdc54) N-terminal domain0Direct
Ribosomal protein L60Direct
CheY-related0Direct
CorA soluble domain-like0Direct
CCCH zinc finger0Direct
Chaperone J-domain0Direct
Actin/HSP700Direct
XPF/Rad1/Mus81 nuclease0Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0Direct
Ypt/Rab-GAP domain of gyp1p0Direct
Glucose 6-phosphate dehydrogenase-like0Direct
Helical domain of Sec23/240Direct
BC ATP-binding domain-like0Direct
HCP-like0Direct
Ankyrin repeat0.2487Inherited
Protein kinases, catalytic subunit0.2945Inherited
Tandem AAA-ATPase domain0.4126Inherited
SH3-domain0.518Inherited
Cold shock DNA-binding domain-like0.518Inherited
Extended AAA-ATPase domain0.7321Inherited
5' to 3' exonuclease catalytic domain0.7321Inherited
FYVE, a phosphatidylinositol-3-phosphate binding domain0.7321Inherited
5' to 3' exonuclease, C-terminal subdomain0.7321Inherited
Inositol polyphosphate 5-phosphatase (IPP5)0.7808Inherited
Cyclophilin (peptidylprolyl isomerase)0.8749Inherited


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Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
SAP domain0Direct
FAD-binding/transporter-associated domain-like0Direct
R3H domain0Direct
HIT/MYND zinc finger-like0Direct
F1F0 ATP synthase subunit C0Direct
Cdc48 domain 2-like0Direct
HRDC-like0Direct
vWA-like0Direct
Glutathione synthetase ATP-binding domain-like0Direct
HMA, heavy metal-associated domain0Direct
YjgF-like0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
GYF domain0Direct
CBS-domain pair0Direct
RBP11-like subunits of RNA polymerase0Direct
Zinc domain conserved in yeast copper-regulated transcription factors0Direct
Fe,Mn superoxide dismutase (SOD), C-terminal domain0Direct
alpha/beta knot0Direct
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain0Direct
Actin depolymerizing proteins0Direct
C-terminal autoproteolytic domain of nucleoporin nup980Direct
Radical SAM enzymes0Direct
Terpenoid cyclases/Protein prenyltransferases0Direct
GAT-like domain0Direct
BRCT domain0Direct
Retrovirus zinc finger-like domains0Direct
Inosine monophosphate dehydrogenase (IMPDH)0Direct
S13-like H2TH domain0Direct
Carbon-nitrogen hydrolase0Direct
UBC-like0Direct
GST C-terminal domain-like0Direct
RmlC-like cupins0Direct
Ribosomal protein L10-like0Direct
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0Direct
Rudiment single hybrid motif0Direct
Ribosomal L11/L12e N-terminal domain0Direct
PA domain0Direct
MurD-like peptide ligases, peptide-binding domain0Direct
Seven-hairpin glycosidases0Direct
Nucleotidylyl transferase0Direct
Bromodomain0Direct
Thiolase-like0Direct
Tubulin nucleotide-binding domain-like0Direct
Nop domain0Direct
ThrRS/AlaRS common domain0Direct
Cytidine deaminase-like0Direct
DNA repair protein MutS, domain I0Direct
HD-domain/PDEase-like0Direct
PR-1-like0Direct
DNA repair protein MutS, domain II0Direct
EPT/RTPC-like0Direct
KA1-like0Direct
Tubulin C-terminal domain-like0Direct
Ligand-binding domain in the NO signalling and Golgi transport0Direct
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0Direct
Six-hairpin glycosidases0Direct
CRAL/TRIO domain0Direct
CCCH zinc finger0Direct
CorA soluble domain-like0Direct
Clavaminate synthase-like0Direct
C-terminal, gelsolin-like domain of Sec23/240Direct
Ribosomal protein L60Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0Direct
Chaperone J-domain0Direct
Amidase signature (AS) enzymes0Direct
Subtilisin-like0Direct
SNARE-like0Direct
VPS9 domain0Direct
PriA/YqbF domain0Direct
L-aspartase-like0Direct
FabD/lysophospholipase-like0Direct
HSP20-like chaperones0Direct
ArfGap/RecO-like zinc finger0Direct
HIT-like0Direct
Kelch motif0Direct
Trimeric LpxA-like enzymes0Direct
Metallo-hydrolase/oxidoreductase0Direct
Nucleoporin domain0Direct
SAICAR synthase-like0Direct
Ribosomal protein L140Direct
PAP/OAS1 substrate-binding domain0Direct
Class II aaRS ABD-related0Direct
WW domain0Direct
Zn-binding ribosomal proteins0Direct
Protein prenylyltransferase0Direct
Carbohydrate phosphatase0Direct
POZ domain0Direct
Ypt/Rab-GAP domain of gyp1p0Direct
Ribosomal protein L11, C-terminal domain0Direct
HMG-box0Direct
LuxS/MPP-like metallohydrolase0Direct
LexA/Signal peptidase0Direct
Alpha-L RNA-binding motif0Direct
Single hybrid motif0Direct
Zn-finger domain of Sec23/240Direct
Nucleotide-binding domain0Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase0Direct
Ribosomal protein L30p/L7e0Direct
Undecaprenyl diphosphate synthase0Direct
Glucocorticoid receptor-like (DNA-binding domain)0Direct
AMPKBI-like0Direct
DNA-glycosylase0Direct
Heat shock protein 70kD (HSP70), C-terminal subdomain0Direct
Heat shock protein 70kD (HSP70), peptide-binding domain0Direct
DNA repair protein MutS, domain III0Direct
Cap-Gly domain0Direct
Cytochrome P4500Direct
Clathrin adaptor appendage domain0Direct
L30e-like0Direct
DNA ligase/mRNA capping enzyme, catalytic domain0Direct
NTF2-like0Direct
CRAL/TRIO N-terminal domain0Direct
Tricorn protease domain 20Direct
Endosomal sorting complex assembly domain0Direct
Oxysterol-binding protein-like0Direct
Ferritin-like0Direct
PYP-like sensor domain (PAS domain)0Direct
Family A G protein-coupled receptor-like0Direct
beta-sandwich domain of Sec23/240Direct
Glycoside hydrolase/deacetylase0Direct
Sec7 domain0Direct
Restriction endonuclease-like0Direct
PUA domain-like0Direct
ALDH-like0Direct
Cysteine alpha-hairpin motif0Direct
SRF-like0Direct
DNA/RNA polymerases0Direct
Smc hinge domain0Direct
Phospholipase D/nuclease0Direct
TK C-terminal domain-like0Direct
Transferrin receptor-like dimerisation domain0Direct
Ribosomal protein S80Direct
Ras GEF0Direct
Sec63 N-terminal domain-like0Direct
DBL homology domain (DH-domain)0Direct
RNase III domain-like0Direct
FAD-linked oxidases, C-terminal domain0Direct
DNA-binding domain of Mlu1-box binding protein MBP10Direct
Magnesium transport protein CorA, transmembrane region0Direct
Prefoldin0Direct
eIF1-like0Direct
HLH, helix-loop-helix DNA-binding domain0Direct
Carbamate kinase-like0Direct
cAMP-binding domain-like0Direct
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0Direct
YVTN repeat-like/Quinoprotein amine dehydrogenase0Direct
DnaJ/Hsp40 cysteine-rich domain0Direct
FAD/NAD-linked reductases, dimerisation (C-terminal) domain0Direct
Arginase/deacetylase0Direct
The spindle assembly checkpoint protein mad20Direct
FMN-binding split barrel0Direct
MurD-like peptide ligases, catalytic domain0Direct
Glutamine synthetase/guanido kinase0Direct
FtsH protease domain-like0Direct
Tim10-like0Direct
RNI-like0Direct
PreATP-grasp domain0Direct
post-HMGL domain-like0Direct
Aconitase iron-sulfur domain0Direct
Cation efflux protein transmembrane domain-like0Direct
Aldolase0Direct
Helical domain of Sec23/240Direct
Alkaline phosphatase-like0Direct
Chromo domain-like0Direct
Terpenoid synthases0Direct
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD0Direct
tRNA-intron endonuclease catalytic domain-like0Direct
Ribulose-phoshate binding barrel0Direct
Translational machinery components0Direct
dsRNA-binding domain-like0Direct
Methylglyoxal synthase-like0Direct
Zn-dependent exopeptidases0Direct
Mitochondrial cytochrome c oxidase subunit IV0Direct
GINS helical bundle-like0Direct
Ribosomal proteins L15p and L18e0Direct
4'-phosphopantetheinyl transferase0Direct
Ribokinase-like0Direct
Adenine nucleotide alpha hydrolases-like0Direct
Ribosomal protein L130Direct
Cytochrome c0Direct
PP2C-like0Direct
ValRS/IleRS/LeuRS editing domain0Direct
HCP-like0Direct
YAP1 redox domain0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Supernatant protein factor (SPF), C-terminal domain0Direct
HSP40/DnaJ peptide-binding domain0Direct
CheY-like0Direct
Class II aaRS and biotin synthetases0.2245Inherited
Ankyrin repeat0.26Inherited
Nucleic acid-binding proteins0.2972Inherited
Class I glutamine amidotransferase-like0.3506Inherited
ENTH/VHS domain0.3506Inherited
"Winged helix" DNA-binding domain0.3751Inherited
Protein kinase-like (PK-like)0.4627Inherited
C2 domain (Calcium/lipid-binding domain, CaLB)0.4654Inherited
ARM repeat0.4995Inherited
Histone-fold0.517Inherited
SH3-domain0.517Inherited
P-loop containing nucleoside triphosphate hydrolases0.6176Inherited
post-AAA+ oligomerization domain-like0.6953Inherited
5' to 3' exonuclease, C-terminal subdomain0.7383Inherited
Cyclophilin-like0.853Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
56053,56053
  • 56053 - Ribosomal protein L6
  • 56053 - Ribosomal protein L6
  • 0Direct
    53067,53067
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 0Direct
    52518,52922
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 52922 - TK C-terminal domain-like
  • 0Direct
    52540,90123
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 90123 - ABC transporter transmembrane region
  • 0Direct
    50249,55681
  • 50249 - Nucleic acid-binding proteins
  • 55681 - Class II aaRS and biotin synthetases
  • 0Direct
    48371,48371
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 0Direct
    53623,53244
  • 53623 - MurD-like peptide ligases, catalytic domain
  • 53244 - MurD-like peptide ligases, peptide-binding domain
  • 0Direct
    49562,49562
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0Direct
    55681,52954
  • 55681 - Class II aaRS and biotin synthetases
  • 52954 - Class II aaRS ABD-related
  • 0Direct
    81301,81631
  • 81301 - Nucleotidyltransferase
  • 81631 - PAP/OAS1 substrate-binding domain
  • 0Direct
    49493,49493
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 0Direct
    51735,55347
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 55347 - Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain
  • 0Direct
    47923,47923
  • 47923 - Ypt/Rab-GAP domain of gyp1p
  • 47923 - Ypt/Rab-GAP domain of gyp1p
  • 0Direct
    48464,89009
  • 48464 - ENTH/VHS domain
  • 89009 - GAT-like domain
  • 0Direct
    57756,57756
  • 57756 - Retrovirus zinc finger-like domains
  • 57756 - Retrovirus zinc finger-like domains
  • 0Direct
    52025,53187
  • 52025 - PA domain
  • 53187 - Zn-dependent exopeptidases
  • 0Direct
    143865,144083
  • 143865 - CorA soluble domain-like
  • 144083 - Magnesium transport protein CorA, transmembrane region
  • 0Direct
    52540,47917
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase
  • 0Direct
    54211,55060
  • 54211 - Ribosomal protein S5 domain 2-like
  • 55060 - GHMP Kinase, C-terminal domain
  • 0Direct
    48334,52540
  • 48334 - DNA repair protein MutS, domain III
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0Direct
    54631,54631
  • 54631 - CBS-domain pair
  • 54631 - CBS-domain pair
  • 0Direct
    53756,56784
  • 53756 - UDP-Glycosyltransferase/glycogen phosphorylase
  • 56784 - HAD-like
  • 0Direct
    50677,52374
  • 50677 - ValRS/IleRS/LeuRS editing domain
  • 52374 - Nucleotidylyl transferase
  • 0Direct
    81995,82919
  • 81995 - beta-sandwich domain of Sec23/24
  • 82919 - Zn-finger domain of Sec23/24
  • 0Direct
    52540,140990
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 140990 - FtsH protease domain-like
  • 0Direct
    56176,55103
  • 56176 - FAD-binding/transporter-associated domain-like
  • 55103 - FAD-linked oxidases, C-terminal domain
  • 0Direct
    90229,90229
  • 90229 - CCCH zinc finger
  • 90229 - CCCH zinc finger
  • 0Direct
    52440,56059
  • 52440 - PreATP-grasp domain
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 0Direct
    52777,52777
  • 52777 - CoA-dependent acyltransferases
  • 52777 - CoA-dependent acyltransferases
  • 0Direct
    46689,46689
  • 46689 - Homeodomain-like
  • 46689 - Homeodomain-like
  • 0Direct
    100920,100934
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
  • 0Direct
    56024,56024
  • 56024 - Phospholipase D/nuclease
  • 56024 - Phospholipase D/nuclease
  • 0Direct
    54747,46906
  • 54747 - Ribosomal L11/L12e N-terminal domain
  • 46906 - Ribosomal protein L11, C-terminal domain
  • 0Direct
    53901,53901
  • 53901 - Thiolase-like
  • 53901 - Thiolase-like
  • 0Direct
    50249,50104
  • 50249 - Nucleic acid-binding proteins
  • 50104 - Translation proteins SH3-like domain
  • 0Direct
    63411,63411
  • 63411 - LuxS/MPP-like metallohydrolase
  • 63411 - LuxS/MPP-like metallohydrolase
  • 0Direct
    52540,53254
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 53254 - Phosphoglycerate mutase-like
  • 0Direct
    53067,100920
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 0Direct
    53613,48613
  • 53613 - Ribokinase-like
  • 48613 - Heme oxygenase-like
  • 0Direct
    50249,50249
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 0Direct
    53098,56672
  • 53098 - Ribonuclease H-like
  • 56672 - DNA/RNA polymerases
  • 0Direct
    55874,54211
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0Direct
    52374,47323
  • 52374 - Nucleotidylyl transferase
  • 47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
  • 0Direct
    52833,47616
  • 52833 - Thioredoxin-like
  • 47616 - GST C-terminal domain-like
  • 0Direct
    56235,52402
  • 56235 - N-terminal nucleophile aminohydrolases (Ntn hydrolases)
  • 52402 - Adenine nucleotide alpha hydrolases-like
  • 0Direct
    48371,52540
  • 48371 - ARM repeat
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    53187,47672
  • 53187 - Zn-dependent exopeptidases
  • 47672 - Transferrin receptor-like dimerisation domain
  • 0Direct
    54631,51412
  • 54631 - CBS-domain pair
  • 51412 - Inosine monophosphate dehydrogenase (IMPDH)
  • 0Direct
    53732,52016
  • 53732 - Aconitase iron-sulfur domain
  • 52016 - LeuD/IlvD-like
  • 0Direct
    63380,52343
  • 63380 - Riboflavin synthase domain-like
  • 52343 - Ferredoxin reductase-like, C-terminal NADP-linked domain
  • 0Direct
    46785,46785
  • 46785 - "Winged helix" DNA-binding domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    56091,50249
  • 56091 - DNA ligase/mRNA capping enzyme, catalytic domain
  • 50249 - Nucleic acid-binding proteins
  • 0Direct
    46938,52087
  • 46938 - CRAL/TRIO N-terminal domain
  • 52087 - CRAL/TRIO domain
  • 0Direct
    52833,52833
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 0Direct
    48452,48452
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 0Direct
    50978,50978
  • 50978 - WD40 repeat-like
  • 50978 - WD40 repeat-like
  • 0Direct
    54897,52743
  • 54897 - Protease propeptides/inhibitors
  • 52743 - Subtilisin-like
  • 0Direct
    103657,50729
  • 103657 - BAR/IMD domain-like
  • 50729 - PH domain-like
  • 0Direct
    82919,53300
  • 82919 - Zn-finger domain of Sec23/24
  • 53300 - vWA-like
  • 0Direct
    53150,48334
  • 53150 - DNA repair protein MutS, domain II
  • 48334 - DNA repair protein MutS, domain III
  • 0Direct
    81811,82754
  • 81811 - Helical domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0Direct
    51569,89000
  • 51569 - Aldolase
  • 89000 - post-HMGL domain-like
  • 0Direct
    46565,57938
  • 46565 - Chaperone J-domain
  • 57938 - DnaJ/Hsp40 cysteine-rich domain
  • 0Direct
    57850,52540
  • 57850 - RING/U-box
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    56059,51246
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 51246 - Rudiment single hybrid motif
  • 0Direct
    51905,51905
  • 51905 - FAD/NAD(P)-binding domain
  • 51905 - FAD/NAD(P)-binding domain
  • 0Direct
    52490,55307
  • 52490 - Tubulin nucleotide-binding domain-like
  • 55307 - Tubulin C-terminal domain-like
  • 0Direct
    57938,49493
  • 57938 - DnaJ/Hsp40 cysteine-rich domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 0Direct
    51905,55424
  • 51905 - FAD/NAD(P)-binding domain
  • 55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain
  • 0Direct
    52518,52518
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 0Direct
    52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.3423Inherited
    52540,48019
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 48019 - post-AAA+ oligomerization domain-like
  • 0.6953Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    53150,48334,52540
  • 53150 - DNA repair protein MutS, domain II
  • 48334 - DNA repair protein MutS, domain III
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    52540,50447,54980
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 54980 - EF-G C-terminal domain-like
  • 0Direct
    52440,56059,51246
  • 52440 - PreATP-grasp domain
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 51246 - Rudiment single hybrid motif
  • 0Direct
    53067,100920,100934
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
  • 0Direct
    46565,57938,49493
  • 46565 - Chaperone J-domain
  • 57938 - DnaJ/Hsp40 cysteine-rich domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 0Direct
    57756,57756,57756
  • 57756 - Retrovirus zinc finger-like domains
  • 57756 - Retrovirus zinc finger-like domains
  • 57756 - Retrovirus zinc finger-like domains
  • 0Direct
    49562,49562,49562
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0Direct
    81995,82919,53300
  • 81995 - beta-sandwich domain of Sec23/24
  • 82919 - Zn-finger domain of Sec23/24
  • 53300 - vWA-like
  • 0Direct
    48452,48452,48452
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 0Direct
    57938,49493,49493
  • 57938 - DnaJ/Hsp40 cysteine-rich domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 0Direct
    48371,48371,48371
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 0Direct
    52540,90123,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    90123,52540,90123
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 90123 - ABC transporter transmembrane region
  • 0Direct
    52025,53187,47672
  • 52025 - PA domain
  • 53187 - Zn-dependent exopeptidases
  • 47672 - Transferrin receptor-like dimerisation domain
  • 0Direct
    48371,52540,52540
  • 48371 - ARM repeat
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    53067,53067,100920
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 0Direct


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