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Yeast Phenotype (YP): fitness

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Root: YP Hierarchy (yeast phenotype from Ascomycete phenotype ontology)

Shortest distance to current term (+ for parents, - for children) YP term [YP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ 1:   observable [APO:0000017] <7>
0:   fitness [APO:0000216] <4>(224|227) (224|80|18)
- 1:   competitive fitness [APO:0000110](221|226) (221|80|18)
- 1:   haploinsufficient [APO:0000152](0|0) (0|0|0)
- 1:   haploproficient [APO:0000330](0|0) (0|0|0)
- 1:   viability [APO:0000111](1|1) (1|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Tim10-like0Direct
Cytidine deaminase-like0Direct
ArfGap/RecO-like zinc finger0Direct
FMN-binding split barrel0Direct
Rudiment single hybrid motif0Direct
Phosphoglucomutase, first 3 domains0Direct
Cation efflux protein transmembrane domain-like0Direct
Ribosomal protein S80Direct
SH3-domain0Direct
EPT/RTPC-like0Direct
Phosphoglucomutase, C-terminal domain0Direct
PR-1-like0Direct
Subtilisin-like0Direct
LexA/Signal peptidase0Direct
C-terminal autoproteolytic domain of nucleoporin nup980Direct
YAP1 redox domain0Direct
Rhodanese/Cell cycle control phosphatase0Direct
CRAL/TRIO N-terminal domain0Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0Direct
Galactose-binding domain-like0Direct
The spindle assembly checkpoint protein mad20Direct
LeuD/IlvD-like0Direct
WW domain0Direct
Supernatant protein factor (SPF), C-terminal domain0Direct
Galactose mutarotase-like0Direct
Ribosomal protein L140Direct
EF-G C-terminal domain-like0Direct
Clathrin adaptor appendage domain0Direct
LDH C-terminal domain-like0Direct
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain0Direct
L-aspartase-like0Direct
E set domains0Direct
PH domain-like0Direct
Oxysterol-binding protein-like0Direct
GroEL-intermediate domain like0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
RCC1/BLIP-II0Direct
SAICAR synthase-like0Direct
Ammonium transporter0Direct
Glycerol-3-phosphate (1)-acyltransferase0Direct
Formate/glycerate dehydrogenase catalytic domain-like0Direct
Cupredoxins0Direct
Carbohydrate phosphatase0Direct
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain0Direct
Activating enzymes of the ubiquitin-like proteins0Direct
Ligand-binding domain in the NO signalling and Golgi transport0Direct
SAP domain0Direct
Prefoldin0Direct
Nudix0Direct
Aconitase iron-sulfur domain0Direct
Glutathione synthetase ATP-binding domain-like0Direct
FabD/lysophospholipase-like0Direct
Pseudouridine synthase0Direct
PP2C-like0Direct
Metallo-dependent phosphatases0Direct
Cytochrome P4500Direct
Oligoxyloglucan reducing end-specific cellobiohydrolase0Direct
4'-phosphopantetheinyl transferase0Direct
NAD kinase/diacylglycerol kinase-like0Direct
PLP-binding barrel0Direct
ClpP/crotonase0Direct
Ferredoxin reductase-like, C-terminal NADP-linked domain0Direct
DPP6 N-terminal domain-like0Direct
DNA ligase/mRNA capping enzyme, catalytic domain0Direct
Trimeric LpxA-like enzymes0Direct
CRAL/TRIO domain0Direct
Mitochondrial cytochrome c oxidase subunit IV0Direct
Protease propeptides/inhibitors0Direct
HLH, helix-loop-helix DNA-binding domain0Direct
Ferritin-like0Direct
PriA/YqbF domain0Direct
Endosomal sorting complex assembly domain0Direct
Glucocorticoid receptor-like (DNA-binding domain)0Direct
Ribokinase-like0Direct
DNA/RNA polymerases0Direct
HD-domain/PDEase-like0Direct
HMG-box0Direct
ValRS/IleRS/LeuRS editing domain0Direct
Creatinase/prolidase N-terminal domain0Direct
HSP20-like chaperones0Direct
HRDC-like0Direct
Ribosomal protein L220Direct
FKBP-like0Direct
DNA repair protein MutS, domain II0Direct
GYF domain0Direct
Methylglyoxal synthase-like0Direct
VPS9 domain0Direct
KA1-like0Direct
Alpha-L RNA-binding motif0Direct
Hect, E3 ligase catalytic domain0Direct
Magnesium transport protein CorA, transmembrane region0Direct
DNA repair protein MutS, domain I0Direct
Multidrug resistance efflux transporter EmrE0Direct
PLC-like phosphodiesterases0Direct
Tubulin nucleotide-binding domain-like0Direct
Sec1/munc18-like (SM) proteins0Direct
GroEL apical domain-like0Direct
Fumarate reductase respiratory complex transmembrane subunits0Direct
Protein prenylyltransferase0Direct
ALDH-like0Direct
Glutamine synthetase/guanido kinase0Direct
PEBP-like0Direct
Seven-hairpin glycosidases0Direct
Clavaminate synthase-like0Direct
Phosphoglycerate mutase-like0Direct
DNA-glycosylase0Direct
HIT/MYND zinc finger-like0Direct
Smc hinge domain0Direct
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0Direct
DNase I-like0Direct
Tricorn protease domain 20Direct
GHMP Kinase, C-terminal domain0Direct
Ras GEF0Direct
Zinc domain conserved in yeast copper-regulated transcription factors0Direct
PX domain0Direct
Heme oxygenase-like0Direct
Riboflavin synthase domain-like0Direct
Chromo domain-like0Direct
post-AAA+ oligomerization domain-like0Direct
F-box domain0Direct
Family A G protein-coupled receptor-like0Direct
Nucleoporin domain0Direct
Rhomboid-like0Direct
HMA, heavy metal-associated domain0Direct
RmlC-like cupins0Direct
Radical SAM enzymes0Direct
Calponin-homology domain, CH-domain0Direct
YjgF-like0Direct
Thioesterase/thiol ester dehydrase-isomerase0Direct
FAD-linked oxidases, C-terminal domain0Direct
Nucleotide-binding domain0Direct
PA domain0Direct
CorA soluble domain-like0Direct
L domain-like0Direct
t-snare proteins0Direct
GST C-terminal domain-like0Direct
PYP-like sensor domain (PAS domain)0Direct
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0Direct
Restriction endonuclease-like0Direct
FAD-binding/transporter-associated domain-like0Direct
FAD-linked reductases, C-terminal domain0Direct
Tubulin C-terminal domain-like0Direct
Ribosomal protein L130Direct
FMN-linked oxidoreductases0Direct
Carbamate kinase-like0Direct
Single hybrid motif0Direct
RNI-like0Direct
DNA repair protein MutS, domain III0Direct
AMPKBI-like0Direct
Transferrin receptor-like dimerisation domain0Direct
GAT-like domain0Direct
MurD-like peptide ligases, peptide-binding domain0Direct
Ribosomal protein L30p/L7e0Direct
Ribosomal protein L60Direct
Cullin homology domain0Direct
ThrRS/AlaRS common domain0Direct
eIF1-like0Direct
RBP11-like subunits of RNA polymerase0Direct
Alkaline phosphatase-like0Direct
Cytochrome b5-like heme/steroid binding domain0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
FAD/NAD-linked reductases, dimerisation (C-terminal) domain0Direct
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD0Direct
Zinc beta-ribbon0Direct
ACT-like0Direct
Nop domain0Direct
NagB/RpiA/CoA transferase-like0Direct
PAP/OAS1 substrate-binding domain0Direct
HSP40/DnaJ peptide-binding domain0Direct
S13-like H2TH domain0Direct
Ankyrin repeat0Direct
Concanavalin A-like lectins/glucanases0Direct
Phospholipase D/nuclease0Direct
Tryptophan synthase beta subunit-like PLP-dependent enzymes0Direct
post-HMGL domain-like0Direct
beta-beta-alpha zinc fingers0Direct
GINS helical bundle-like0Direct
Amidase signature (AS) enzymes0Direct
SRF-like0Direct
Aminoacid dehydrogenase-like, N-terminal domain0Direct
GroEL equatorial domain-like0Direct
Sialidases0Direct
Acid proteases0Direct
PIN domain-like0Direct
CheY-like0Direct
FtsH protease domain-like0Direct
Translational machinery components0Direct
F1F0 ATP synthase subunit C0Direct
MurD-like peptide ligases, catalytic domain0Direct
Six-hairpin glycosidases0Direct
PreATP-grasp domain0Direct
GTPase activation domain, GAP0Direct
Ubiquitin-like0Direct
Aldolase0Direct
DnaJ/Hsp40 cysteine-rich domain0Direct
UBA-like0Direct
Ypt/Rab-GAP domain of gyp1p0Direct
FAD-linked oxidoreductase0Direct
Cdc48 domain 2-like0Direct
Cyclophilin-like0Direct
Thiolase-like0Direct
BAR/IMD domain-like0Direct
Cap-Gly domain0Direct
Kelch motif0Direct
R3H domain0Direct
TGS-like0Direct
Aquaporin-like0Direct
Cytochrome c0Direct
Sec63 N-terminal domain-like0Direct
(Phosphotyrosine protein) phosphatases II0Direct
5' to 3' exonuclease, C-terminal subdomain0Direct
tRNA-intron endonuclease catalytic domain-like0Direct
Regulator of G-protein signaling, RGS0Direct
Phosphoenolpyruvate/pyruvate domain0Direct
Acyl-CoA N-acyltransferases (Nat)0Direct
Citrate synthase0Direct
CCCH zinc finger0Direct
SpoIIaa-like0Direct
DNA-binding domain of Mlu1-box binding protein MBP10Direct
Actin depolymerizing proteins0Direct
Nucleotidyltransferase0Direct
Metallo-dependent hydrolases0Direct
Cullin repeat-like0Direct
Mss4-like0Direct


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Ribosomal protein L130Direct
Oxysterol-binding protein0Direct
Class I glutamine amidotransferases (GAT)0Direct
Tetrahydrofolate dehydrogenase/cyclohydrolase0Direct
DnaQ-like 3'-5' exonuclease0Direct
Ribokinase-like0Direct
SAP domain0Direct
Cyclin0Direct
WW domain0Direct
TENA/THI-40Direct
Clathrin adaptor core protein0Direct
Glutathione S-transferase (GST), N-terminal domain0Direct
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain0Direct
FabD-like0Direct
GAPDH-like0Direct
Dual specificity phosphatase-like0Direct
VPS9 domain0Direct
Inositol monophosphatase/fructose-1,6-bisphosphatase-like0Direct
Cofactor-dependent phosphoglycerate mutase0Direct
Sec1/munc18-like (SM) proteins0Direct
Ras GEF0Direct
FMN-linked oxidoreductases0Direct
Phosphoglucomutase, first 3 domains0Direct
Forkhead DNA-binding domain0Direct
HLH, helix-loop-helix DNA-binding domain0Direct
HSP40/DnaJ peptide-binding domain0Direct
HMGL-like0Direct
Glycolipid 2-alpha-mannosyltransferase0Direct
Vacuolar sorting protein domain0Direct
C-terminal domain of ribosomal protein L20Direct
Hect, E3 ligase catalytic domain0Direct
Phosphoglucomutase, C-terminal domain0Direct
VHS domain0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Histidine acid phosphatase0Direct
RuBisCo LSMT catalytic domain0Direct
Ribosomal protein S80Direct
PR-1-like0Direct
Ribosomal protein L140Direct
Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain0Direct
YAP1 redox domain0Direct
Aminoacid dehydrogenase-like, C-terminal domain0Direct
Ubiquitin-related0Direct
Ribosomal protein S130Direct
Erythroid transcription factor GATA-10Direct
Lysophospholipase0Direct
Choline/Carnitine O-acyltransferase0Direct
C-terminal autoproteolytic domain of nucleoporin nup980Direct
FAD-linked oxidases, N-terminal domain0Direct
Group II chaperonin (CCT, TRIC), ATPase domain0Direct
RecA protein-like (ATPase-domain)0Direct
AMPK-beta glycogen binding domain-like0Direct
TBP-associated factors, TAFs0Direct
DNA gyrase/MutL, N-terminal domain0Direct
Subtilase propeptides/inhibitors0Direct
Pyruvate oxidase and decarboxylase PP module0Direct
Hexokinase0Direct
Cyclophilin (peptidylprolyl isomerase)0Direct
UBA domain0Direct
Phosphatidylethanolamine binding protein0Direct
Thiamin biosynthesis kinases0Direct
Single strand DNA-binding domain, SSB0Direct
Reductases0Direct
GYF domain0Direct
MIF4G domain-like0Direct
RING finger domain, C3HC40Direct
NADPH-cytochrome p450 reductase FAD-binding domain-like0Direct
DNA ligase/mRNA capping enzyme postcatalytic domain0Direct
Lactate & malate dehydrogenases, C-terminal domain0Direct
Transcriptional factor domain0Direct
FCH domain0Direct
Cullin homology domain0Direct
ALDH-like0Direct
DNA repair protein MutS, domain I0Direct
AAT-like0Direct
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain0Direct
Pseudouridine synthase RsuA/RluD0Direct
Aconitase iron-sulfur domain0Direct
Class I alpha-1;2-mannosidase, catalytic domain0Direct
Pyk2-associated protein beta ARF-GAP domain0Direct
5' to 3' exonuclease catalytic domain0Direct
Group II chaperonin (CCT, TRIC), intermediate domain0Direct
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD0Direct
SH3-domain0Direct
Heat-shock transcription factor0Direct
Zinc domain conserved in yeast copper-regulated transcription factors0Direct
LeuD-like0Direct
Bacteriorhodopsin-like0Direct
FYVE, a phosphatidylinositol-3-phosphate binding domain0Direct
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0Direct
Crotonase-like0Direct
Trehalose-6-phosphate synthase, OtsA0Direct
Ubiquitin activating enzymes (UBA)0Direct
NADPH-cytochrome p450 reductase-like0Direct
Cofilin-like0Direct
AMPKBI-like0Direct
Cytochrome b50Direct
NAD kinase-like0Direct
PP2C-like0Direct
Pyruvate oxidase and decarboxylase Pyr module0Direct
PyrH-like0Direct
SWIRM domain0Direct
Glutathione S-transferase (GST), C-terminal domain0Direct
Ribosomal protein L18 and S110Direct
NLI interacting factor-like phosphatase0Direct
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain0Direct
Translational machinery components0Direct
Ankyrin repeat0Direct
N-acetyl transferase, NAT0Direct
DNA-binding domain of Mlu1-box binding protein MBP10Direct
tRNA-intron endonuclease catalytic domain-like0Direct
Tubulin, C-terminal domain0Direct
Formate/glycerate dehydrogenases, substrate-binding domain0Direct
Clathrin coat assembly domain0Direct
Prefoldin0Direct
Calponin-homology domain, CH-domain0Direct
Amidase signature (AS) enzymes0Direct
Leukotriene A4 hydrolase catalytic domain0Direct
Cdc48 domain 2-like0Direct
TRAPP components0Direct
Biotinyl/lipoyl-carrier proteins and domains0Direct
Class I aldolase0Direct
Tetratricopeptide repeat (TPR)0Direct
Thiolase-related0Direct
Serine carboxypeptidase-like0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Citrate synthase0Direct
L-aspartase/fumarase0Direct
Multidomain cupredoxins0Direct
Smc hinge domain0Direct
PDI-like0Direct
Transferrin receptor-like dimerisation domain0Direct
Tryptophan synthase beta subunit-like PLP-dependent enzymes0Direct
Ribosomal protein S40Direct
DNA polymerase III clamp loader subunits, C-terminal domain0Direct
Formate/glycerate dehydrogenases, NAD-domain0Direct
SCF ubiquitin ligase complex WHB domain0Direct
HMG-box0Direct
Pleckstrin-homology domain (PH domain)0Direct
Nucleosome core histones0Direct
Aldose 1-epimerase (mutarotase)0Direct
Glycosyl hydrolases family 160Direct
Myb/SANT domain0Direct
RNA-polymerase beta-prime0Direct
Cytochrome P4500Direct
FAD/NAD-linked reductases, dimerisation (C-terminal) domain0Direct
t-snare proteins0Direct
BC C-terminal domain-like0Direct
Pseudouridine synthase I TruA0Direct
IF2B-like0Direct
Subtilases0Direct
Ferredoxin reductase FAD-binding domain-like0Direct
Eps15 homology domain (EH domain)0Direct
La domain0Direct
Magnesium transport protein CorA, transmembrane region0Direct
Ran-binding domain0Direct
Phosphoribulokinase/pantothenate kinase0Direct
BC N-terminal domain-like0Direct
Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain0Direct
DnaJ/Hsp40 cysteine-rich domain0Direct
Cation efflux protein transmembrane domain-like0Direct
RNB domain-like0Direct
PA domain0Direct
ValRS/IleRS/LeuRS editing domain0Direct
Class I aminoacyl-tRNA synthetases (RS), catalytic domain0Direct
FKBP immunophilin/proline isomerase0Direct
Regulator of G-protein signaling, RGS0Direct
Aquaporin-like0Direct
DNA gyrase/MutL, second domain0Direct
CRAL/TRIO domain0Direct
EF-G/eEF-2 domains III and V0Direct
Glutathione peroxidase-like0Direct
GHMP Kinase, N-terminal domain0Direct
Pepsin-like0Direct
Cap-Gly domain0Direct
YjgF/L-PSP0Direct
eIF1-like0Direct
DNA repair protein MutS, domain III0Direct
Higher-molecular-weight phosphotyrosine protein phosphatases0Direct
Inositol polyphosphate 5-phosphatase (IPP5)0Direct
Gastric lipase0Direct
Deoxycytidylate deaminase-like0Direct
5' to 3' exonuclease, C-terminal subdomain0Direct
DNA polymerase I0Direct
Tryptophan biosynthesis enzymes0Direct
Ribosomal protein L220Direct
Adenosine/AMP deaminase0Direct
FtsH protease domain-like0Direct
CRAL/TRIO N-terminal domain0Direct
Ammonium transporter0Direct
BCR-homology GTPase activation domain (BH-domain)0Direct
Tubulin, GTPase domain0Direct
LDH N-terminal domain-like0Direct
Nop domain0Direct
ENTH domain0Direct
Tim10/DDP0Direct
Protein serine/threonine phosphatase0Direct
NagB-like0Direct
Pyruvate oxidase and decarboxylase, middle domain0Direct
PX domain0Direct
NOL1/NOP2/sun0Direct
beta-glycanases0Direct
Pumilio repeat0Direct
HMA, heavy metal-associated domain0Direct
Cytochrome p450 reductase N-terminal domain-like0Direct
FAD-linked reductases, N-terminal domain0Direct
Glycosyl transferases group 10Direct
p120GAP domain-like0Direct
F-box domain0Direct
SRF-like0Direct
RNA methyltransferase FtsJ0Direct
Folylpolyglutamate synthetase0Direct
Ribosomal protein L30p/L7e0Direct
Phosphate binding protein-like0Direct
Group II chaperonin (CCT, TRIC), apical domain0Direct
Ribosomal protein L60Direct
Classic zinc finger, C2H20Direct
CheY-related0Direct
CorA soluble domain-like0Direct
CCCH zinc finger0Direct
XPF/Rad1/Mus81 nuclease0Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0Direct
Ypt/Rab-GAP domain of gyp1p0Direct
Aminoacid dehydrogenases0Direct
Glucose 6-phosphate dehydrogenase-like0Direct
BC ATP-binding domain-like0Direct
HCP-like0Direct


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Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
SAP domain0Direct
Ribosomal protein L220Direct
L domain-like0Direct
5' to 3' exonuclease, C-terminal subdomain0Direct
GroEL equatorial domain-like0Direct
FAD-binding/transporter-associated domain-like0Direct
R3H domain0Direct
HIT/MYND zinc finger-like0Direct
F1F0 ATP synthase subunit C0Direct
Cdc48 domain 2-like0Direct
Sec1/munc18-like (SM) proteins0Direct
HRDC-like0Direct
Nucleotidyltransferase0Direct
TGS-like0Direct
Glutathione synthetase ATP-binding domain-like0Direct
HMA, heavy metal-associated domain0Direct
Phosphoglucomutase, C-terminal domain0Direct
Heme oxygenase-like0Direct
YjgF-like0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
GYF domain0Direct
LeuD/IlvD-like0Direct
Sialidases0Direct
RBP11-like subunits of RNA polymerase0Direct
Zinc domain conserved in yeast copper-regulated transcription factors0Direct
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain0Direct
Actin depolymerizing proteins0Direct
GroEL apical domain-like0Direct
C-terminal autoproteolytic domain of nucleoporin nup980Direct
PLP-binding barrel0Direct
Radical SAM enzymes0Direct
UBA-like0Direct
GAT-like domain0Direct
Zinc beta-ribbon0Direct
FKBP-like0Direct
Regulator of G-protein signaling, RGS0Direct
E set domains0Direct
S13-like H2TH domain0Direct
DNase I-like0Direct
NagB/RpiA/CoA transferase-like0Direct
Rhomboid-like0Direct
GST C-terminal domain-like0Direct
Hect, E3 ligase catalytic domain0Direct
RmlC-like cupins0Direct
Aminoacid dehydrogenase-like, N-terminal domain0Direct
Rudiment single hybrid motif0Direct
BAR/IMD domain-like0Direct
PA domain0Direct
MurD-like peptide ligases, peptide-binding domain0Direct
Cullin repeat-like0Direct
Seven-hairpin glycosidases0Direct
Cupredoxins0Direct
Thiolase-like0Direct
Tubulin nucleotide-binding domain-like0Direct
Nop domain0Direct
ThrRS/AlaRS common domain0Direct
Cytidine deaminase-like0Direct
DNA repair protein MutS, domain I0Direct
HD-domain/PDEase-like0Direct
beta-beta-alpha zinc fingers0Direct
PR-1-like0Direct
DPP6 N-terminal domain-like0Direct
DNA repair protein MutS, domain II0Direct
EPT/RTPC-like0Direct
Ammonium transporter0Direct
KA1-like0Direct
Oligoxyloglucan reducing end-specific cellobiohydrolase0Direct
FAD-linked oxidoreductase0Direct
Tubulin C-terminal domain-like0Direct
Ligand-binding domain in the NO signalling and Golgi transport0Direct
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0Direct
Six-hairpin glycosidases0Direct
Cytochrome b5-like heme/steroid binding domain0Direct
CRAL/TRIO domain0Direct
CCCH zinc finger0Direct
CorA soluble domain-like0Direct
Clavaminate synthase-like0Direct
Ribosomal protein L60Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0Direct
Amidase signature (AS) enzymes0Direct
Subtilisin-like0Direct
SH3-domain0Direct
VPS9 domain0Direct
NAD kinase/diacylglycerol kinase-like0Direct
PriA/YqbF domain0Direct
L-aspartase-like0Direct
FabD/lysophospholipase-like0Direct
HSP20-like chaperones0Direct
ArfGap/RecO-like zinc finger0Direct
Kelch motif0Direct
Trimeric LpxA-like enzymes0Direct
Nucleoporin domain0Direct
SAICAR synthase-like0Direct
Ferredoxin reductase-like, C-terminal NADP-linked domain0Direct
LDH C-terminal domain-like0Direct
Ribosomal protein L140Direct
Calponin-homology domain, CH-domain0Direct
PAP/OAS1 substrate-binding domain0Direct
Mss4-like0Direct
WW domain0Direct
Protein prenylyltransferase0Direct
Carbohydrate phosphatase0Direct
Ypt/Rab-GAP domain of gyp1p0Direct
Creatinase/prolidase N-terminal domain0Direct
HMG-box0Direct
LexA/Signal peptidase0Direct
Alpha-L RNA-binding motif0Direct
Single hybrid motif0Direct
Nucleotide-binding domain0Direct
Ribosomal protein L30p/L7e0Direct
SpoIIaa-like0Direct
Galactose mutarotase-like0Direct
Glucocorticoid receptor-like (DNA-binding domain)0Direct
AMPKBI-like0Direct
DNA-glycosylase0Direct
GHMP Kinase, C-terminal domain0Direct
Acid proteases0Direct
Aquaporin-like0Direct
PEBP-like0Direct
PIN domain-like0Direct
DNA repair protein MutS, domain III0Direct
Cap-Gly domain0Direct
Cytochrome P4500Direct
Metallo-dependent phosphatases0Direct
Clathrin adaptor appendage domain0Direct
Protease propeptides/inhibitors0Direct
t-snare proteins0Direct
ClpP/crotonase0Direct
DNA ligase/mRNA capping enzyme, catalytic domain0Direct
CRAL/TRIO N-terminal domain0Direct
Pseudouridine synthase0Direct
Tricorn protease domain 20Direct
F-box domain0Direct
Endosomal sorting complex assembly domain0Direct
Citrate synthase0Direct
Oxysterol-binding protein-like0Direct
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain0Direct
GTPase activation domain, GAP0Direct
Phosphoglucomutase, first 3 domains0Direct
RCC1/BLIP-II0Direct
PLC-like phosphodiesterases0Direct
Ferritin-like0Direct
PYP-like sensor domain (PAS domain)0Direct
PH domain-like0Direct
Multidrug resistance efflux transporter EmrE0Direct
Family A G protein-coupled receptor-like0Direct
Galactose-binding domain-like0Direct
Restriction endonuclease-like0Direct
Cyclophilin-like0Direct
ALDH-like0Direct
Cullin homology domain0Direct
SRF-like0Direct
Formate/glycerate dehydrogenase catalytic domain-like0Direct
DNA/RNA polymerases0Direct
Ubiquitin-like0Direct
Smc hinge domain0Direct
Phospholipase D/nuclease0Direct
Transferrin receptor-like dimerisation domain0Direct
Ribosomal protein S80Direct
FMN-linked oxidoreductases0Direct
Ras GEF0Direct
Sec63 N-terminal domain-like0Direct
Phosphoenolpyruvate/pyruvate domain0Direct
FAD-linked oxidases, C-terminal domain0Direct
(Phosphotyrosine protein) phosphatases II0Direct
DNA-binding domain of Mlu1-box binding protein MBP10Direct
EF-G C-terminal domain-like0Direct
Ankyrin repeat0Direct
Fumarate reductase respiratory complex transmembrane subunits0Direct
Magnesium transport protein CorA, transmembrane region0Direct
Prefoldin0Direct
Activating enzymes of the ubiquitin-like proteins0Direct
GroEL-intermediate domain like0Direct
eIF1-like0Direct
HLH, helix-loop-helix DNA-binding domain0Direct
Carbamate kinase-like0Direct
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0Direct
DnaJ/Hsp40 cysteine-rich domain0Direct
FAD/NAD-linked reductases, dimerisation (C-terminal) domain0Direct
The spindle assembly checkpoint protein mad20Direct
PX domain0Direct
ACT-like0Direct
FAD-linked reductases, C-terminal domain0Direct
Nudix0Direct
FMN-binding split barrel0Direct
Acyl-CoA N-acyltransferases (Nat)0Direct
MurD-like peptide ligases, catalytic domain0Direct
Glutamine synthetase/guanido kinase0Direct
post-AAA+ oligomerization domain-like0Direct
FtsH protease domain-like0Direct
Tim10-like0Direct
RNI-like0Direct
PreATP-grasp domain0Direct
post-HMGL domain-like0Direct
Aconitase iron-sulfur domain0Direct
Thioesterase/thiol ester dehydrase-isomerase0Direct
Cation efflux protein transmembrane domain-like0Direct
Aldolase0Direct
Riboflavin synthase domain-like0Direct
Alkaline phosphatase-like0Direct
Chromo domain-like0Direct
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD0Direct
tRNA-intron endonuclease catalytic domain-like0Direct
Translational machinery components0Direct
Tryptophan synthase beta subunit-like PLP-dependent enzymes0Direct
Glycerol-3-phosphate (1)-acyltransferase0Direct
Methylglyoxal synthase-like0Direct
Rhodanese/Cell cycle control phosphatase0Direct
Concanavalin A-like lectins/glucanases0Direct
Mitochondrial cytochrome c oxidase subunit IV0Direct
GINS helical bundle-like0Direct
4'-phosphopantetheinyl transferase0Direct
Ribokinase-like0Direct
Ribosomal protein L130Direct
Cytochrome c0Direct
PP2C-like0Direct
Metallo-dependent hydrolases0Direct
Phosphoglycerate mutase-like0Direct
ValRS/IleRS/LeuRS editing domain0Direct
YAP1 redox domain0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Supernatant protein factor (SPF), C-terminal domain0Direct
HSP40/DnaJ peptide-binding domain0Direct
CheY-like0Direct

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
56053,56053
  • 56053 - Ribosomal protein L6
  • 56053 - Ribosomal protein L6
  • 0Direct
    54849,52029
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0Direct
    52540,90123
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 90123 - ABC transporter transmembrane region
  • 0Direct
    53623,53244
  • 53623 - MurD-like peptide ligases, catalytic domain
  • 53244 - MurD-like peptide ligases, peptide-binding domain
  • 0Direct
    50447,54980
  • 50447 - Translation proteins
  • 54980 - EF-G C-terminal domain-like
  • 0Direct
    49562,49562
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0Direct
    81301,81631
  • 81301 - Nucleotidyltransferase
  • 81631 - PAP/OAS1 substrate-binding domain
  • 0Direct
    49493,49493
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 0Direct
    51735,55347
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 55347 - Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain
  • 0Direct
    47923,47923
  • 47923 - Ypt/Rab-GAP domain of gyp1p
  • 47923 - Ypt/Rab-GAP domain of gyp1p
  • 0Direct
    53738,53738
  • 53738 - Phosphoglucomutase, first 3 domains
  • 53738 - Phosphoglucomutase, first 3 domains
  • 0Direct
    48464,89009
  • 48464 - ENTH/VHS domain
  • 89009 - GAT-like domain
  • 0Direct
    57756,57756
  • 57756 - Retrovirus zinc finger-like domains
  • 57756 - Retrovirus zinc finger-like domains
  • 0Direct
    52025,53187
  • 52025 - PA domain
  • 53187 - Zn-dependent exopeptidases
  • 0Direct
    143865,144083
  • 143865 - CorA soluble domain-like
  • 144083 - Magnesium transport protein CorA, transmembrane region
  • 0Direct
    52540,47917
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase
  • 0Direct
    54211,55060
  • 54211 - Ribosomal protein S5 domain 2-like
  • 55060 - GHMP Kinase, C-terminal domain
  • 0Direct
    48334,52540
  • 48334 - DNA repair protein MutS, domain III
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0Direct
    52518,52467
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 52467 - DHS-like NAD/FAD-binding domain
  • 0Direct
    54631,54631
  • 54631 - CBS-domain pair
  • 54631 - CBS-domain pair
  • 0Direct
    53756,56784
  • 53756 - UDP-Glycosyltransferase/glycogen phosphorylase
  • 56784 - HAD-like
  • 0Direct
    50677,52374
  • 50677 - ValRS/IleRS/LeuRS editing domain
  • 52374 - Nucleotidylyl transferase
  • 0Direct
    48592,54849
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 0Direct
    47661,58038
  • 47661 - t-snare proteins
  • 58038 - SNARE fusion complex
  • 0Direct
    52540,140990
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 140990 - FtsH protease domain-like
  • 0Direct
    54928,54928
  • 54928 - RNA-binding domain, RBD
  • 54928 - RNA-binding domain, RBD
  • 0Direct
    52058,52058
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 0Direct
    56176,55103
  • 56176 - FAD-binding/transporter-associated domain-like
  • 55103 - FAD-linked oxidases, C-terminal domain
  • 0Direct
    90229,90229
  • 90229 - CCCH zinc finger
  • 90229 - CCCH zinc finger
  • 0Direct
    52440,56059
  • 52440 - PreATP-grasp domain
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 0Direct
    52777,52777
  • 52777 - CoA-dependent acyltransferases
  • 52777 - CoA-dependent acyltransferases
  • 0Direct
    46689,46689
  • 46689 - Homeodomain-like
  • 46689 - Homeodomain-like
  • 0Direct
    52540,48019
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 48019 - post-AAA+ oligomerization domain-like
  • 0Direct
    56024,56024
  • 56024 - Phospholipase D/nuclease
  • 56024 - Phospholipase D/nuclease
  • 0Direct
    88723,47807
  • 88723 - PIN domain-like
  • 47807 - 5' to 3' exonuclease, C-terminal subdomain
  • 0Direct
    53901,53901
  • 53901 - Thiolase-like
  • 53901 - Thiolase-like
  • 0Direct
    50249,50104
  • 50249 - Nucleic acid-binding proteins
  • 50104 - Translation proteins SH3-like domain
  • 0Direct
    52540,53254
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 53254 - Phosphoglycerate mutase-like
  • 0Direct
    51735,56327
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 56327 - LDH C-terminal domain-like
  • 0Direct
    57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 0Direct
    53613,48613
  • 53613 - Ribokinase-like
  • 48613 - Heme oxygenase-like
  • 0Direct
    50249,50249
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 0Direct
    51905,56425
  • 51905 - FAD/NAD(P)-binding domain
  • 56425 - Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain
  • 0Direct
    53098,56672
  • 53098 - Ribonuclease H-like
  • 56672 - DNA/RNA polymerases
  • 0Direct
    55874,54211
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0Direct
    52374,47323
  • 52374 - Nucleotidylyl transferase
  • 47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
  • 0Direct
    52833,47616
  • 52833 - Thioredoxin-like
  • 47616 - GST C-terminal domain-like
  • 0Direct
    56235,52402
  • 56235 - N-terminal nucleophile aminohydrolases (Ntn hydrolases)
  • 52402 - Adenine nucleotide alpha hydrolases-like
  • 0Direct
    53187,47672
  • 53187 - Zn-dependent exopeptidases
  • 47672 - Transferrin receptor-like dimerisation domain
  • 0Direct
    52540,81271
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 81271 - TGS-like
  • 0Direct
    53732,52016
  • 53732 - Aconitase iron-sulfur domain
  • 52016 - LeuD/IlvD-like
  • 0Direct
    49503,49503
  • 49503 - Cupredoxins
  • 49503 - Cupredoxins
  • 0Direct
    63380,52343
  • 63380 - Riboflavin synthase domain-like
  • 52343 - Ferredoxin reductase-like, C-terminal NADP-linked domain
  • 0Direct
    53738,55957
  • 53738 - Phosphoglucomutase, first 3 domains
  • 55957 - Phosphoglucomutase, C-terminal domain
  • 0Direct
    46785,46785
  • 46785 - "Winged helix" DNA-binding domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    56091,50249
  • 56091 - DNA ligase/mRNA capping enzyme, catalytic domain
  • 50249 - Nucleic acid-binding proteins
  • 0Direct
    46938,52087
  • 46938 - CRAL/TRIO N-terminal domain
  • 52087 - CRAL/TRIO domain
  • 0Direct
    52833,52833
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 0Direct
    50978,50978
  • 50978 - WD40 repeat-like
  • 50978 - WD40 repeat-like
  • 0Direct
    54897,52743
  • 54897 - Protease propeptides/inhibitors
  • 52743 - Subtilisin-like
  • 0Direct
    103657,50729
  • 103657 - BAR/IMD domain-like
  • 50729 - PH domain-like
  • 0Direct
    103473,103473
  • 103473 - MFS general substrate transporter
  • 103473 - MFS general substrate transporter
  • 0Direct
    51905,54373
  • 51905 - FAD/NAD(P)-binding domain
  • 54373 - FAD-linked reductases, C-terminal domain
  • 0Direct
    52467,52518
  • 52467 - DHS-like NAD/FAD-binding domain
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 0Direct
    52283,51735
  • 52283 - Formate/glycerate dehydrogenase catalytic domain-like
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0Direct
    53150,48334
  • 53150 - DNA repair protein MutS, domain II
  • 48334 - DNA repair protein MutS, domain III
  • 0Direct
    51569,89000
  • 51569 - Aldolase
  • 89000 - post-HMGL domain-like
  • 0Direct
    54980,54211
  • 54980 - EF-G C-terminal domain-like
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0Direct
    46565,57938
  • 46565 - Chaperone J-domain
  • 57938 - DnaJ/Hsp40 cysteine-rich domain
  • 0Direct
    57850,52540
  • 57850 - RING/U-box
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    54211,54980
  • 54211 - Ribosomal protein S5 domain 2-like
  • 54980 - EF-G C-terminal domain-like
  • 0Direct
    56059,51246
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 51246 - Rudiment single hybrid motif
  • 0Direct
    54791,54791
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 0Direct
    51905,51905
  • 51905 - FAD/NAD(P)-binding domain
  • 51905 - FAD/NAD(P)-binding domain
  • 0Direct
    52490,55307
  • 52490 - Tubulin nucleotide-binding domain-like
  • 55307 - Tubulin C-terminal domain-like
  • 0Direct
    57938,49493
  • 57938 - DnaJ/Hsp40 cysteine-rich domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 0Direct
    75632,46785
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    51905,55424
  • 51905 - FAD/NAD(P)-binding domain
  • 55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain
  • 0Direct
    53223,51735
  • 53223 - Aminoacid dehydrogenase-like, N-terminal domain
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0Direct

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    53150,48334,52540
  • 53150 - DNA repair protein MutS, domain II
  • 48334 - DNA repair protein MutS, domain III
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    53738,53738,55957
  • 53738 - Phosphoglucomutase, first 3 domains
  • 53738 - Phosphoglucomutase, first 3 domains
  • 55957 - Phosphoglucomutase, C-terminal domain
  • 0Direct
    52540,50447,54980
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 54980 - EF-G C-terminal domain-like
  • 0Direct
    52440,56059,51246
  • 52440 - PreATP-grasp domain
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 51246 - Rudiment single hybrid motif
  • 0Direct
    49503,49503,49503
  • 49503 - Cupredoxins
  • 49503 - Cupredoxins
  • 49503 - Cupredoxins
  • 0Direct
    46565,57938,49493
  • 46565 - Chaperone J-domain
  • 57938 - DnaJ/Hsp40 cysteine-rich domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 0Direct
    57756,57756,57756
  • 57756 - Retrovirus zinc finger-like domains
  • 57756 - Retrovirus zinc finger-like domains
  • 57756 - Retrovirus zinc finger-like domains
  • 0Direct
    50447,54980,54211
  • 50447 - Translation proteins
  • 54980 - EF-G C-terminal domain-like
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0Direct
    49562,49562,49562
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0Direct
    52518,52467,52518
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 52467 - DHS-like NAD/FAD-binding domain
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 0Direct
    48592,54849,52029
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0Direct
    48452,48452,48452
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 0Direct
    57938,49493,49493
  • 57938 - DnaJ/Hsp40 cysteine-rich domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 0Direct
    54980,54211,54980
  • 54980 - EF-G C-terminal domain-like
  • 54211 - Ribosomal protein S5 domain 2-like
  • 54980 - EF-G C-terminal domain-like
  • 0Direct
    53738,53738,53738
  • 53738 - Phosphoglucomutase, first 3 domains
  • 53738 - Phosphoglucomutase, first 3 domains
  • 53738 - Phosphoglucomutase, first 3 domains
  • 0Direct
    52540,90123,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    90123,52540,90123
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 90123 - ABC transporter transmembrane region
  • 0Direct
    52025,53187,47672
  • 52025 - PA domain
  • 53187 - Zn-dependent exopeptidases
  • 47672 - Transferrin receptor-like dimerisation domain
  • 0Direct


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