SUPERFAMILY 1.75 HMM library and genome assignments server

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Lesion bypass DNA polymerase (Y-family), little finger domain superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   Lesion bypass DNA polymerase (Y-family), little finger domain [ 100878]
Superfamily:   Lesion bypass DNA polymerase (Y-family), little finger domain [ 100879]
Families:   Lesion bypass DNA polymerase (Y-family), little finger domain [ 100880] (5)


Superfamily statistics
Genomes (2,489) Uniprot 2017_06 genome PDB chains (SCOP 1.75)
Domains 4,601 25,905 17
Proteins 4,599 25,893 17


Functional annotation
General category Information
Detailed category DNA replication/repair

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) cellular nitrogen compound metabolic process 0 Least Informative Direct
Biological Process (BP) cellular aromatic compound metabolic process 0 Least Informative Direct
Biological Process (BP) heterocycle metabolic process 0 Least Informative Direct
Biological Process (BP) organic cyclic compound metabolic process 0 Least Informative Direct
Biological Process (BP) response to stimulus 0.000000000000003734 Least Informative Direct
Biological Process (BP) macromolecule metabolic process 0.000000000004067 Least Informative Direct
Biological Process (BP) biosynthetic process 0.000000008652 Least Informative Direct
Biological Process (BP) primary metabolic process 0.00000002511 Least Informative Direct
Biological Process (BP) cellular response to stress 0 Moderately Informative Direct
Biological Process (BP) cellular macromolecule biosynthetic process 0.0000000000001047 Moderately Informative Direct
Biological Process (BP) aromatic compound biosynthetic process 0.0000000001422 Moderately Informative Direct
Biological Process (BP) heterocycle biosynthetic process 0.0000000005258 Moderately Informative Direct
Biological Process (BP) organic cyclic compound biosynthetic process 0.000000004214 Moderately Informative Direct
Biological Process (BP) response to external stimulus 0.9875 Moderately Informative Inherited
Biological Process (BP) cell communication 0.4032 Moderately Informative Inherited
Biological Process (BP) response to abiotic stimulus 0.5037 Moderately Informative Inherited
Biological Process (BP) cellular response to DNA damage stimulus 0 Informative Direct
Biological Process (BP) DNA metabolic process 0 Informative Direct
Biological Process (BP) response to extracellular stimulus 0.00000009275 Informative Direct
Biological Process (BP) response to radiation 0.00000009919 Informative Direct
Biological Process (BP) response to UV 0.0000000000001202 Highly Informative Direct
Biological Process (BP) cellular response to extracellular stimulus 0.00089 Highly Informative Direct
Molecular Function (MF) transferase activity 0.000000000001124 Least Informative Direct
Molecular Function (MF) transferase activity, transferring phosphorus-containing groups 0.00000002425 Moderately Informative Direct
Molecular Function (MF) nucleotidyltransferase activity 0 Informative Direct
Cellular Component (CC) intracellular organelle part 0.02148 Least Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 0.1598 Least Informative Inherited
Cellular Component (CC) intracellular organelle lumen 0.000131 Moderately Informative Direct
Cellular Component (CC) nuclear part 0.0006341 Moderately Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Nucleotidyltransferases0Least InformativeDirect
Enzyme Commission (EC)DNA-directed DNA polymerase0Moderately InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processDNA damage0Moderately InformativeDirect
Biological processDNA replication0InformativeDirect
Biological processDNA repair0InformativeDirect
Biological processDNA synthesis0Highly InformativeDirect
Biological processSOS response1Highly InformativeInherited
Cellular componentCytoplasm0Least InformativeDirect
Molecular functionMetal-binding0Least InformativeDirect
Molecular functionMagnesium0Least InformativeDirect
Post-translational modificationTransferase0Least InformativeDirect
Post-translational modificationDNA-binding0Moderately InformativeDirect
Post-translational modificationNucleotidyltransferase0Moderately InformativeDirect
Post-translational modificationDNA-directed DNA polymerase0Highly InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 6 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Lesion bypass DNA polymerase (Y-family), little finger domain domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 6 hidden Markov models representing the Lesion bypass DNA polymerase (Y-family), little finger domain superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · Internal database links ]