SUPERFAMILY 1.75 HMM library and genome assignments server

NagB/RpiA/CoA transferase-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (147)
Fold:   NagB/RpiA/CoA transferase-like [ 100949]
Superfamily:   NagB/RpiA/CoA transferase-like [ 100950] (8)
Families:   NagB-like [ 52513] (2)
  D-ribose-5-phosphate isomerase (RpiA), catalytic domain [ 75176]
  CoA transferase beta subunit-like [ 74657] (3)
  CoA transferase alpha subunit-like [ 74656] (6)
  IF2B-like [ 110513] (5)
  Methenyltetrahydrofolate synthetase [ 110520] (3)
  YkgG-like [ 142200]
  SorC sugar-binding domain-like [ 159545] (5)


Superfamily statistics
Genomes (3,199) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 34,403 219,592 41
Proteins 31,228 196,804 34


Functional annotation
General category Metabolism
Detailed category Transferases

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)nitrogen compound metabolic process11Least InformativeInherited
Biological Process (BP)regulation of cellular process0.99881Least InformativeInherited
Biological Process (BP)single-organism metabolic process0.8470.0001292Least InformativeInherited
Biological Process (BP)multicellular organismal process0.29961Least InformativeInherited
Biological Process (BP)biosynthetic process0.70070.2067Least InformativeInherited
Biological Process (BP)response to stimulus0.88611Least InformativeInherited
Biological Process (BP)positive regulation of biological process0.5011Least InformativeInherited
Biological Process (BP)localization0.96961Least InformativeInherited
Biological Process (BP)regulation of metabolic process0.10610.7342Least InformativeInherited
Biological Process (BP)developmental process0.025531Least InformativeInherited
Biological Process (BP)heterocycle metabolic process0.84061Least InformativeInherited
Biological Process (BP)organic cyclic compound metabolic process0.96541Least InformativeInherited
Biological Process (BP)cellular macromolecule metabolic process11Least InformativeInherited
Biological Process (BP)protein metabolic process0.12070.9337Least InformativeInherited
Biological Process (BP)single-organism cellular process0.1830.1635Least InformativeInherited
Biological Process (BP)cellular aromatic compound metabolic process0.61121Least InformativeInherited
Biological Process (BP)gene expression0.0000020940.0000000002614Moderately InformativeDirect
Biological Process (BP)cellular macromolecule biosynthetic process0.00000040140.00000000002429Moderately InformativeDirect
Biological Process (BP)cofactor metabolic process0.0000065030Moderately InformativeDirect
Biological Process (BP)oxidation-reduction process0.00087850.0000001572Moderately InformativeDirect
Biological Process (BP)organic substance catabolic process0.00029750.000009196Moderately InformativeDirect
Biological Process (BP)nucleobase-containing small molecule metabolic process0.012690.0000000169Moderately InformativeInherited
Biological Process (BP)single-organism catabolic process0.017810.000002766Moderately InformativeInherited
Biological Process (BP)regulation of nucleobase-containing compound metabolic process0.012850.1774Moderately InformativeInherited
Biological Process (BP)positive regulation of molecular function0.080270.006618Moderately InformativeInherited
Biological Process (BP)regulation of catalytic activity0.00088950.002642Moderately InformativeInherited
Biological Process (BP)reproductive process0.000021940.006874Moderately InformativeInherited
Biological Process (BP)response to organic substance0.56140.9391Moderately InformativeInherited
Biological Process (BP)response to oxygen-containing compound0.27530.1719Moderately InformativeInherited
Biological Process (BP)positive regulation of cellular process0.261Moderately InformativeInherited
Biological Process (BP)positive regulation of metabolic process0.044490.7095Moderately InformativeInherited
Biological Process (BP)organophosphate metabolic process0.2090.004432Moderately InformativeInherited
Biological Process (BP)phosphate-containing compound metabolic process0.14921Moderately InformativeInherited
Biological Process (BP)carbohydrate metabolic process0.093220.000002344Moderately InformativeInherited
Biological Process (BP)cell differentiation0.00055920.3293Moderately InformativeInherited
Biological Process (BP)response to abiotic stimulus0.044840.0925Moderately InformativeInherited
Biological Process (BP)organ development0.64231Moderately InformativeInherited
Biological Process (BP)cellular localization0.20510.6418Moderately InformativeInherited
Biological Process (BP)multi-organism process0.033710.5942Moderately InformativeInherited
Biological Process (BP)nervous system development0.00017710.05012Moderately InformativeInherited
Biological Process (BP)cellular amino acid metabolic process0.1470.1907Moderately InformativeInherited
Biological Process (BP)regulation of protein metabolic process0.75130.7987Moderately InformativeInherited
Biological Process (BP)regulation of gene expression0.5040.9285Moderately InformativeInherited
Biological Process (BP)regulation of macromolecule biosynthetic process0.21820.5757Moderately InformativeInherited
Biological Process (BP)regulation of cellular biosynthetic process0.62040.6936Moderately InformativeInherited
Biological Process (BP)regulation of phosphorus metabolic process0.0038530.02901Moderately InformativeInherited
Biological Process (BP)carbohydrate derivative metabolic process0.023490.4092Moderately InformativeInherited
Biological Process (BP)central nervous system development0.000000012180.00003644InformativeDirect
Biological Process (BP)regulation of nucleoside metabolic process0.0000015850.00000001397InformativeDirect
Biological Process (BP)positive regulation of catabolic process0.0000006070.0000002253InformativeDirect
Biological Process (BP)regulation of cellular catabolic process0.000034460.00001031InformativeDirect
Biological Process (BP)positive regulation of phosphate metabolic process0.00036650.000925InformativeDirect
Biological Process (BP)positive regulation of hydrolase activity0.0000033060.000009623InformativeDirect
Biological Process (BP)pyridine-containing compound metabolic process0.000000010370InformativeDirect
Biological Process (BP)regulation of purine nucleotide metabolic process0.0000021320.0000001856InformativeDirect
Biological Process (BP)carbohydrate catabolic process0.010560.00000003771InformativeInherited
Biological Process (BP)carbohydrate derivative catabolic process0.001080.3343InformativeInherited
Biological Process (BP)multicellular organismal reproductive process0.43970.08168InformativeInherited
Biological Process (BP)oxidoreduction coenzyme metabolic process0.016450.00007022InformativeInherited
Biological Process (BP)hexose metabolic process0.00000034780.0329InformativeInherited
Biological Process (BP)vesicle-mediated transport0.029180.4123InformativeInherited
Biological Process (BP)reproductive structure development0.0043020.005951InformativeInherited
Biological Process (BP)secretion by cell0.00037790.06515InformativeInherited
Biological Process (BP)single organism reproductive process0.000012340.002793InformativeInherited
Biological Process (BP)sexual reproduction0.52381InformativeInherited
Biological Process (BP)cellular modified amino acid metabolic process0.00024890.02036InformativeInherited
Biological Process (BP)posttranscriptional regulation of gene expression0.0051920.004578InformativeInherited
Biological Process (BP)glucose metabolic process0.000000058690Highly InformativeDirect
Biological Process (BP)amino sugar metabolic process00Highly InformativeDirect
Biological Process (BP)translational initiation00Highly InformativeDirect
Biological Process (BP)regulation of translation0.00047150.00004948Highly InformativeDirect
Biological Process (BP)folic acid-containing compound metabolic process0.0000013420.0005059Highly InformativeDirect
Biological Process (BP)ensheathment of neurons0.000000001490.0000000000019Highly InformativeDirect
Biological Process (BP)gonad development0.000068930.0000001727Highly InformativeDirect
Biological Process (BP)response to heat0.00037190.00000295Highly InformativeDirect
Biological Process (BP)fertilization0.000057390.0006346Highly InformativeDirect
Biological Process (BP)response to carbohydrate0.000056490.0004034Highly InformativeDirect
Biological Process (BP)glial cell differentiation0.00000000000038480.000000000000003707Highly InformativeDirect
Biological Process (BP)ovulation cycle process0.00000019760.00000000001381Highly InformativeDirect
Biological Process (BP)positive regulation of GTPase activity0.000000014390.000000000224Highly InformativeDirect
Biological Process (BP)monosaccharide catabolic process0.00000000046450.000000000003342Highly InformativeDirect
Biological Process (BP)nicotinamide nucleotide metabolic process0.00000000015710Highly InformativeDirect
Biological Process (BP)development of primary female sexual characteristics0.000000057720.00000000004267Highly InformativeDirect
Biological Process (BP)exocytosis0.0000093220.00146Highly InformativeInherited
Molecular Function (MF)hydrolase activity11Least InformativeInherited
Molecular Function (MF)transferase activity10.9217Least InformativeInherited
Molecular Function (MF)binding0.35231Least InformativeInherited
Molecular Function (MF)isomerase activity0.000000000000043990Moderately InformativeDirect
Molecular Function (MF)hydrolase activity, acting on ester bonds0.0023390.0000006757Moderately InformativeInherited
Molecular Function (MF)anion binding0.0067990.08147Moderately InformativeInherited
Molecular Function (MF)carbohydrate derivative binding0.0013350.02227Moderately InformativeInherited
Molecular Function (MF)nucleic acid binding0.000000000035880.001432Moderately InformativeInherited
Molecular Function (MF)small molecule binding0.0065440.008466Moderately InformativeInherited
Molecular Function (MF)RNA binding0.00029290.0000000005793InformativeDirect
Molecular Function (MF)transferase activity, transferring sulfur-containing groups0.0000000016310InformativeDirect
Molecular Function (MF)intramolecular oxidoreductase activity00InformativeDirect
Molecular Function (MF)purine ribonucleoside binding0.000075160.0008115InformativeDirect
Molecular Function (MF)purine ribonucleoside triphosphate binding0.000038880.0008571InformativeDirect
Molecular Function (MF)nucleotide binding0.00045920.09263InformativeInherited
Molecular Function (MF)ligase activity0.000015160.01567InformativeInherited
Molecular Function (MF)guanyl-nucleotide exchange factor activity00Highly InformativeDirect
Molecular Function (MF)translation factor activity, nucleic acid binding00Highly InformativeDirect
Molecular Function (MF)intramolecular oxidoreductase activity, interconverting aldoses and ketoses00Highly InformativeDirect
Molecular Function (MF)deaminase activity00Highly InformativeDirect
Molecular Function (MF)carboxylic ester hydrolase activity0.0000000031770.000000000111Highly InformativeDirect
Cellular Component (CC)protein complex0.0024180.07574Least InformativeInherited
Cellular Component (CC)cytoplasmic part0.24550.0000003259Least InformativeInherited

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) single-organism metabolic process 0.0001292 Least Informative Direct
Biological Process (BP) nitrogen compound metabolic process 1 Least Informative Inherited
Biological Process (BP) organic cyclic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) single-organism cellular process 0.1635 Least Informative Inherited
Biological Process (BP) regulation of cellular process 1 Least Informative Inherited
Biological Process (BP) multicellular organismal process 1 Least Informative Inherited
Biological Process (BP) biosynthetic process 0.2067 Least Informative Inherited
Biological Process (BP) response to stimulus 1 Least Informative Inherited
Biological Process (BP) positive regulation of biological process 1 Least Informative Inherited
Biological Process (BP) localization 1 Least Informative Inherited
Biological Process (BP) regulation of metabolic process 0.7342 Least Informative Inherited
Biological Process (BP) developmental process 1 Least Informative Inherited
Biological Process (BP) heterocycle metabolic process 1 Least Informative Inherited
Biological Process (BP) cellular macromolecule metabolic process 1 Least Informative Inherited
Biological Process (BP) protein metabolic process 0.9337 Least Informative Inherited
Biological Process (BP) cellular aromatic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) carbohydrate metabolic process 0.000002344 Moderately Informative Direct
Biological Process (BP) gene expression 0.0000000002614 Moderately Informative Direct
Biological Process (BP) cellular macromolecule biosynthetic process 0.00000000002429 Moderately Informative Direct
Biological Process (BP) single-organism catabolic process 0.000002766 Moderately Informative Direct
Biological Process (BP) cofactor metabolic process 0 Moderately Informative Direct
Biological Process (BP) nucleobase-containing small molecule metabolic process 0.0000000169 Moderately Informative Direct
Biological Process (BP) oxidation-reduction process 0.0000001572 Moderately Informative Direct
Biological Process (BP) organic substance catabolic process 0.000009196 Moderately Informative Direct
Biological Process (BP) regulation of nucleobase-containing compound metabolic process 0.1774 Moderately Informative Inherited
Biological Process (BP) positive regulation of molecular function 0.006618 Moderately Informative Inherited
Biological Process (BP) regulation of catalytic activity 0.002642 Moderately Informative Inherited
Biological Process (BP) positive regulation of metabolic process 0.7095 Moderately Informative Inherited
Biological Process (BP) reproductive process 0.006874 Moderately Informative Inherited
Biological Process (BP) nervous system development 0.05012 Moderately Informative Inherited
Biological Process (BP) cellular catabolic process 1 Moderately Informative Inherited
Biological Process (BP) response to organic substance 0.9391 Moderately Informative Inherited
Biological Process (BP) response to oxygen-containing compound 0.1719 Moderately Informative Inherited
Biological Process (BP) positive regulation of cellular process 1 Moderately Informative Inherited
Biological Process (BP) organophosphate metabolic process 0.004432 Moderately Informative Inherited
Biological Process (BP) phosphate-containing compound metabolic process 1 Moderately Informative Inherited
Biological Process (BP) cell differentiation 0.3293 Moderately Informative Inherited
Biological Process (BP) response to abiotic stimulus 0.0925 Moderately Informative Inherited
Biological Process (BP) organ development 1 Moderately Informative Inherited
Biological Process (BP) cellular localization 0.6418 Moderately Informative Inherited
Biological Process (BP) multi-organism process 0.5942 Moderately Informative Inherited
Biological Process (BP) cellular amino acid metabolic process 0.1907 Moderately Informative Inherited
Biological Process (BP) regulation of protein metabolic process 0.7987 Moderately Informative Inherited
Biological Process (BP) regulation of gene expression 0.9285 Moderately Informative Inherited
Biological Process (BP) regulation of macromolecule biosynthetic process 0.5757 Moderately Informative Inherited
Biological Process (BP) regulation of cellular biosynthetic process 0.6936 Moderately Informative Inherited
Biological Process (BP) macromolecule localization 0.6283 Moderately Informative Inherited
Biological Process (BP) regulation of phosphorus metabolic process 0.02901 Moderately Informative Inherited
Biological Process (BP) monocarboxylic acid metabolic process 0.2065 Moderately Informative Inherited
Biological Process (BP) carbohydrate derivative metabolic process 0.4092 Moderately Informative Inherited
Biological Process (BP) oxidoreduction coenzyme metabolic process 0.00007022 Informative Direct
Biological Process (BP) central nervous system development 0.00003644 Informative Direct
Biological Process (BP) regulation of nucleoside metabolic process 0.00000001397 Informative Direct
Biological Process (BP) positive regulation of catabolic process 0.0000002253 Informative Direct
Biological Process (BP) carbohydrate catabolic process 0.00000003771 Informative Direct
Biological Process (BP) regulation of cellular catabolic process 0.00001031 Informative Direct
Biological Process (BP) cellular ketone metabolic process 0.0001762 Informative Direct
Biological Process (BP) positive regulation of phosphate metabolic process 0.000925 Informative Direct
Biological Process (BP) positive regulation of hydrolase activity 0.000009623 Informative Direct
Biological Process (BP) pyridine-containing compound metabolic process 0 Informative Direct
Biological Process (BP) regulation of purine nucleotide metabolic process 0.0000001856 Informative Direct
Biological Process (BP) carbohydrate derivative catabolic process 0.3343 Informative Inherited
Biological Process (BP) multicellular organismal reproductive process 0.08168 Informative Inherited
Biological Process (BP) hexose metabolic process 0.0329 Informative Inherited
Biological Process (BP) vesicle-mediated transport 0.4123 Informative Inherited
Biological Process (BP) reproductive structure development 0.005951 Informative Inherited
Biological Process (BP) secretion by cell 0.06515 Informative Inherited
Biological Process (BP) single organism reproductive process 0.002793 Informative Inherited
Biological Process (BP) sexual reproduction 1 Informative Inherited
Biological Process (BP) cellular modified amino acid metabolic process 0.02036 Informative Inherited
Biological Process (BP) posttranscriptional regulation of gene expression 0.004578 Informative Inherited
Biological Process (BP) glucose metabolic process 0 Highly Informative Direct
Biological Process (BP) amino sugar metabolic process 0 Highly Informative Direct
Biological Process (BP) translational initiation 0 Highly Informative Direct
Biological Process (BP) regulation of translation 0.00004948 Highly Informative Direct
Biological Process (BP) folic acid-containing compound metabolic process 0.0005059 Highly Informative Direct
Biological Process (BP) ensheathment of neurons 0.0000000000019 Highly Informative Direct
Biological Process (BP) gonad development 0.0000001727 Highly Informative Direct
Biological Process (BP) response to heat 0.00000295 Highly Informative Direct
Biological Process (BP) fertilization 0.0006346 Highly Informative Direct
Biological Process (BP) response to carbohydrate 0.0004034 Highly Informative Direct
Biological Process (BP) glial cell differentiation 0.000000000000003707 Highly Informative Direct
Biological Process (BP) pentose metabolic process 0.0005735 Highly Informative Direct
Biological Process (BP) ovulation cycle process 0.00000000001381 Highly Informative Direct
Biological Process (BP) positive regulation of GTPase activity 0.000000000224 Highly Informative Direct
Biological Process (BP) monosaccharide catabolic process 0.000000000003342 Highly Informative Direct
Biological Process (BP) nicotinamide nucleotide metabolic process 0 Highly Informative Direct
Biological Process (BP) development of primary female sexual characteristics 0.00000000004267 Highly Informative Direct
Biological Process (BP) exocytosis 0.00146 Highly Informative Inherited
Molecular Function (MF) hydrolase activity 1 Least Informative Inherited
Molecular Function (MF) transferase activity 0.9217 Least Informative Inherited
Molecular Function (MF) binding 1 Least Informative Inherited
Molecular Function (MF) hydrolase activity, acting on ester bonds 0.0000006757 Moderately Informative Direct
Molecular Function (MF) isomerase activity 0 Moderately Informative Direct
Molecular Function (MF) anion binding 0.08147 Moderately Informative Inherited
Molecular Function (MF) carbohydrate derivative binding 0.02227 Moderately Informative Inherited
Molecular Function (MF) oxidoreductase activity 1 Moderately Informative Inherited
Molecular Function (MF) nucleic acid binding 0.001432 Moderately Informative Inherited
Molecular Function (MF) small molecule binding 0.008466 Moderately Informative Inherited
Molecular Function (MF) RNA binding 0.0000000005793 Informative Direct
Molecular Function (MF) oxidoreductase activity, acting on CH-OH group of donors 0.0002616 Informative Direct
Molecular Function (MF) transferase activity, transferring sulfur-containing groups 0 Informative Direct
Molecular Function (MF) intramolecular oxidoreductase activity 0 Informative Direct
Molecular Function (MF) purine ribonucleoside binding 0.0008115 Informative Direct
Molecular Function (MF) purine ribonucleoside triphosphate binding 0.0008571 Informative Direct
Molecular Function (MF) nucleotide binding 0.09263 Informative Inherited
Molecular Function (MF) ligase activity 0.01567 Informative Inherited
Molecular Function (MF) guanyl-nucleotide exchange factor activity 0 Highly Informative Direct
Molecular Function (MF) translation factor activity, nucleic acid binding 0 Highly Informative Direct
Molecular Function (MF) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 0.0001072 Highly Informative Direct
Molecular Function (MF) intramolecular oxidoreductase activity, interconverting aldoses and ketoses 0 Highly Informative Direct
Molecular Function (MF) deaminase activity 0 Highly Informative Direct
Molecular Function (MF) carboxylic ester hydrolase activity 0.000000000111 Highly Informative Direct
Molecular Function (MF) thiolester hydrolase activity 0.01427 Highly Informative Inherited
Cellular Component (CC) cytoplasmic part 0.0000003259 Least Informative Direct
Cellular Component (CC) protein complex 0.07574 Least Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 1 Least Informative Inherited

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Isomerases0Least InformativeDirect
Enzyme Commission (EC)Ligases1Least InformativeInherited
Enzyme Commission (EC)Acting on ester bonds1Least InformativeInherited
Enzyme Commission (EC)Intramolecular oxidoreductases0Moderately InformativeDirect
Enzyme Commission (EC)Carboxylic ester hydrolases0.00000000000001442Moderately InformativeDirect
Enzyme Commission (EC)Forming carbon-nitrogen bonds1Moderately InformativeInherited
Enzyme Commission (EC)Interconverting aldoses and ketoses, and related c0InformativeDirect
Enzyme Commission (EC)Thiolester hydrolases0.00002533InformativeDirect
Enzyme Commission (EC)Cyclo-ligases0.01457InformativeInherited
Enzyme Commission (EC)In other compounds0Highly InformativeDirect

Document: EC annotation of SCOP domains

Human Phenotype (HP)

(show details) Document: HP annotation of SCOP domains

Worm Phenotype (WP)

(show details) Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details) Document: YP annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)genital system0Least InformativeDirect
Xenopus ANatomical entity (XAN)male organism0Least InformativeDirect
Xenopus ANatomical entity (XAN)viscus0Least InformativeDirect
Xenopus ANatomical entity (XAN)gonad0Least InformativeDirect

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant structure DEvelopment stage (PDE)LP.04 four leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.06 six leaves visible stage0Least InformativeDirect

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Hydrolases0.000176Least InformativeDirect
Enzyme Commission (EC)Oxidoreductases1Least InformativeInherited
Enzyme Commission (EC)Lyases1Least InformativeInherited
Enzyme Commission (EC)Acting on carbon-nitrogen bonds, other than peptide bonds0Moderately InformativeDirect
Enzyme Commission (EC)Isomerases0Moderately InformativeDirect
Enzyme Commission (EC)Acting on the CH-OH group of donors1Moderately InformativeInherited
Enzyme Commission (EC)Carbon-carbon lyases1Moderately InformativeInherited
Enzyme Commission (EC)Ligases1Moderately InformativeInherited
Enzyme Commission (EC)Intramolecular oxidoreductases0InformativeDirect
Enzyme Commission (EC)Carboxylic ester hydrolases0.000000000000008035InformativeDirect
Enzyme Commission (EC)With NAD(+) or NADP(+) as acceptor1InformativeInherited
Enzyme Commission (EC)Interconverting aldoses and ketoses, and related compounds0Highly InformativeDirect
Enzyme Commission (EC)Cyclo-ligases0.0001102Highly InformativeDirect
Enzyme Commission (EC)Oxo-acid-lyases0.3596Highly InformativeInherited

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processAmino-acid biosynthesis0Moderately InformativeDirect
Biological processCarbohydrate metabolism0Moderately InformativeDirect
Biological processMethionine biosynthesis0Highly InformativeDirect
Post-translational modificationHydrolase0.000002164Least InformativeDirect
Post-translational modificationIsomerase0Moderately InformativeDirect
Post-translational modificationRepressor0.000002682Moderately InformativeDirect
Post-translational modificationInitiation factor0.00000001762InformativeDirect

Document: KW annotation of SCOP domains

UniProtKB UniPathway (UP)

(show details)
UP termFDR (all)SDUP levelAnnotation (direct or inherited)
UniPathway (UP)carbohydrate metabolism0Least InformativeDirect
UniPathway (UP)amino-acid metabolism0.2581Least InformativeInherited
UniPathway (UP)aromatic compound metabolism1Least InformativeInherited
UniPathway (UP)lipid metabolism1Least InformativeInherited
UniPathway (UP)carbohydrate degradation0Moderately InformativeDirect
UniPathway (UP)amine and polyamine metabolism0Moderately InformativeDirect
UniPathway (UP)proteinogenic amino-acid biosynthesis8.993e-16Moderately InformativeDirect
UniPathway (UP)fatty acid metabolism1Moderately InformativeInherited
UniPathway (UP)amino-sugar metabolism0InformativeDirect
UniPathway (UP)amine and polyamine degradation0InformativeDirect
UniPathway (UP)L-methionine biosynthesis0InformativeDirect
UniPathway (UP)pentose phosphate pathway0Highly InformativeDirect
UniPathway (UP)N-acetylneuraminate degradation0Highly InformativeDirect
UniPathway (UP)L-methionine biosynthesis via salvage pathway0Highly InformativeDirect
UniPathway (UP)beta-ketoadipate pathway0.0000004692Highly InformativeDirect
UniPathway (UP)ketone degradation1Highly InformativeInherited

Document: UP annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Human Phenotype (HP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 32 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a NagB/RpiA/CoA transferase-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 32 hidden Markov models representing the NagB/RpiA/CoA transferase-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Human Phenotype (HP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) · Internal database links ]