SUPERFAMILY 1.75 HMM library and genome assignments server


NagB/RpiA/CoA transferase-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (147)
Fold:   NagB/RpiA/CoA transferase-like [ 100949]
Superfamily:   NagB/RpiA/CoA transferase-like [ 100950] (8)
Families:   NagB-like [ 52513] (2)
  D-ribose-5-phosphate isomerase (RpiA), catalytic domain [ 75176]
  CoA transferase beta subunit-like [ 74657] (3)
  CoA transferase alpha subunit-like [ 74656] (6)
  IF2B-like [ 110513] (5)
  Methenyltetrahydrofolate synthetase [ 110520] (3)
  YkgG-like [ 142200]
  SorC sugar-binding domain-like [ 159545] (5)


Superfamily statistics
Genomes (3,198) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 34,381 219,592 41
Proteins 31,209 196,804 34


Functional annotation
General category Metabolism
Detailed category Transferases

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)response to stimulus0.88571Least InformativeInherited
Biological Process (BP)regulation of metabolic process0.0098920.3612Least InformativeInherited
Biological Process (BP)regulation of cellular process0.67421Least InformativeInherited
Biological Process (BP)single-organism cellular process11Least InformativeInherited
Biological Process (BP)multicellular organismal process0.33651Least InformativeInherited
Biological Process (BP)developmental process0.024711Least InformativeInherited
Biological Process (BP)localization0.94241Least InformativeInherited
Biological Process (BP)single-organism metabolic process0.99340.01536Least InformativeInherited
Biological Process (BP)heterocycle metabolic process0.81361Least InformativeInherited
Biological Process (BP)nitrogen compound metabolic process0.99541Least InformativeInherited
Biological Process (BP)organic cyclic compound metabolic process0.95661Least InformativeInherited
Biological Process (BP)cellular aromatic compound metabolic process0.5781Least InformativeInherited
Biological Process (BP)cellular macromolecule metabolic process11Least InformativeInherited
Biological Process (BP)biosynthetic process0.72790.2799Least InformativeInherited
Biological Process (BP)protein metabolic process0.12120.922Least InformativeInherited
Biological Process (BP)gene expression1.128e-066.082e-11Moderately InformativeDirect
Biological Process (BP)cellular macromolecule biosynthetic process3.983e-071.81e-11Moderately InformativeDirect
Biological Process (BP)regulation of catalytic activity3.306e-065.566e-05Moderately InformativeDirect
Biological Process (BP)cofactor metabolic process3.616e-060Moderately InformativeDirect
Biological Process (BP)carbohydrate metabolic process0.095141.989e-06Moderately InformativeInherited
Biological Process (BP)positive regulation of molecular function0.015870.001556Moderately InformativeInherited
Biological Process (BP)regulation of nucleobase-containing compound metabolic process8.568e-050.02839Moderately InformativeInherited
Biological Process (BP)response to organic substance0.54970.9169Moderately InformativeInherited
Biological Process (BP)response to oxygen-containing compound0.2670.154Moderately InformativeInherited
Biological Process (BP)regulation of phosphate metabolic process10.0002351Moderately InformativeInherited
Biological Process (BP)system process0.022830.278Moderately InformativeInherited
Biological Process (BP)regulation of biological quality0.2521Moderately InformativeInherited
Biological Process (BP)cell differentiation0.00049690.2918Moderately InformativeInherited
Biological Process (BP)nervous system development0.00014120.04456Moderately InformativeInherited
Biological Process (BP)response to abiotic stimulus0.044240.08341Moderately InformativeInherited
Biological Process (BP)single-organism developmental process0.031891Moderately InformativeInherited
Biological Process (BP)organ development0.65751Moderately InformativeInherited
Biological Process (BP)cellular localization0.1940.5989Moderately InformativeInherited
Biological Process (BP)cellular amino acid metabolic process0.16340.199Moderately InformativeInherited
Biological Process (BP)phosphate-containing compound metabolic process0.11821Moderately InformativeInherited
Biological Process (BP)organophosphate metabolic process0.18170.002982Moderately InformativeInherited
Biological Process (BP)nucleobase-containing small molecule metabolic process0.016750.0001849Moderately InformativeInherited
Biological Process (BP)regulation of gene expression0.32970.7814Moderately InformativeInherited
Biological Process (BP)regulation of macromolecule biosynthetic process0.21330.5377Moderately InformativeInherited
Biological Process (BP)regulation of cellular biosynthetic process11Moderately InformativeInherited
Biological Process (BP)regulation of protein metabolic process0.8530.6977Moderately InformativeInherited
Biological Process (BP)carbohydrate derivative metabolic process0.017810.3386Moderately InformativeInherited
Biological Process (BP)reproduction0.00011010.02373Moderately InformativeInherited
Biological Process (BP)central nervous system development8.884e-092.901e-05InformativeDirect
Biological Process (BP)regulation of nucleoside metabolic process2.775e-099.015e-12InformativeDirect
Biological Process (BP)regulation of cellular catabolic process5.303e-095.384e-09InformativeDirect
Biological Process (BP)single organism reproductive process3.651e-081.089e-05InformativeDirect
Biological Process (BP)positive regulation of hydrolase activity1.914e-106.136e-07InformativeDirect
Biological Process (BP)pyridine-containing compound metabolic process6.345e-090InformativeDirect
Biological Process (BP)regulation of purine nucleotide metabolic process7.352e-119.785e-11InformativeDirect
Biological Process (BP)carbohydrate derivative catabolic process0.0010420.2989InformativeInherited
Biological Process (BP)oxidoreduction coenzyme metabolic process0.02666.92e-05InformativeInherited
Biological Process (BP)multicellular organismal reproductive process0.5450.1291InformativeInherited
Biological Process (BP)vesicle-mediated transport0.028650.3946InformativeInherited
Biological Process (BP)secretion by cell7.752e-050.034InformativeInherited
Biological Process (BP)sexual reproduction0.14480.5051InformativeInherited
Biological Process (BP)cellular process involved in reproduction0.0068190.272InformativeInherited
Biological Process (BP)cellular modified amino acid metabolic process0.00030150.02159InformativeInherited
Biological Process (BP)posttranscriptional regulation of gene expression0.0050970.004292InformativeInherited
Biological Process (BP)carbohydrate catabolic process0.011111.587e-08InformativeInherited
Biological Process (BP)hexose metabolic process1.503e-060.05464InformativeInherited
Biological Process (BP)reproductive system development0.0041730.001925InformativeInherited
Biological Process (BP)developmental process involved in reproduction0.18760.00992InformativeInherited
Biological Process (BP)amino sugar metabolic process00Highly InformativeDirect
Biological Process (BP)translational initiation00Highly InformativeDirect
Biological Process (BP)regulation of translation0.00044794.839e-05Highly InformativeDirect
Biological Process (BP)folic acid-containing compound metabolic process1.487e-060.0004769Highly InformativeDirect
Biological Process (BP)gonad development7.9e-061.379e-07Highly InformativeDirect
Biological Process (BP)response to heat0.00037812.798e-06Highly InformativeDirect
Biological Process (BP)response to carbohydrate stimulus5.543e-050.0003648Highly InformativeDirect
Biological Process (BP)glial cell differentiation4.561e-133.741e-15Highly InformativeDirect
Biological Process (BP)ovulation cycle process7.721e-081.659e-11Highly InformativeDirect
Biological Process (BP)regulation of membrane potential3.007e-073.276e-07Highly InformativeDirect
Biological Process (BP)nicotinamide nucleotide metabolic process1.723e-100Highly InformativeDirect
Biological Process (BP)development of primary female sexual characteristics1.394e-072.037e-10Highly InformativeDirect
Biological Process (BP)exocytosis9.573e-060.001318Highly InformativeInherited
Biological Process (BP)fertilization0.00041330.00476Highly InformativeInherited
Molecular Function (MF)binding0.33991Least InformativeInherited
Molecular Function (MF)hydrolase activity11Least InformativeInherited
Molecular Function (MF)transferase activity10.6937Least InformativeInherited
Molecular Function (MF)isomerase activity4.6e-140Moderately InformativeDirect
Molecular Function (MF)enzyme regulator activity1.656e-088.535e-10Moderately InformativeDirect
Molecular Function (MF)anion binding0.0067660.07564Moderately InformativeInherited
Molecular Function (MF)hydrolase activity, acting on ester bonds0.0022215.342e-07Moderately InformativeInherited
Molecular Function (MF)nucleic acid binding9.94e-120.001511Moderately InformativeInherited
Molecular Function (MF)RNA binding9.659e-056.319e-11InformativeDirect
Molecular Function (MF)intramolecular oxidoreductase activity00InformativeDirect
Molecular Function (MF)GTPase regulator activity3.664e-141.185e-14InformativeDirect
Molecular Function (MF)purine ribonucleoside binding7.565e-050.000768InformativeDirect
Molecular Function (MF)purine ribonucleoside triphosphate binding3.861e-050.0008913InformativeDirect
Molecular Function (MF)nucleotide binding0.00045720.4094InformativeInherited
Molecular Function (MF)ligase activity, forming carbon-nitrogen bonds6.646e-070.001709InformativeInherited
Molecular Function (MF)guanyl-nucleotide exchange factor activity00Highly InformativeDirect
Molecular Function (MF)translation factor activity, nucleic acid binding00Highly InformativeDirect
Molecular Function (MF)intramolecular oxidoreductase activity, interconverting aldoses and ketoses00Highly InformativeDirect
Molecular Function (MF)deaminase activity00Highly InformativeDirect
Molecular Function (MF)carboxylic ester hydrolase activity3.226e-091.211e-10Highly InformativeDirect
Cellular Component (CC)protein complex0.0024890.1427Least InformativeInherited
Cellular Component (CC)cytoplasmic part0.23581.847e-07Least InformativeInherited

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) response to stimulus 1 Least Informative Inherited
Biological Process (BP) regulation of metabolic process 0.3612 Least Informative Inherited
Biological Process (BP) regulation of cellular process 1 Least Informative Inherited
Biological Process (BP) single-organism cellular process 1 Least Informative Inherited
Biological Process (BP) multicellular organismal process 1 Least Informative Inherited
Biological Process (BP) developmental process 1 Least Informative Inherited
Biological Process (BP) single-organism metabolic process 0.01536 Least Informative Inherited
Biological Process (BP) heterocycle metabolic process 1 Least Informative Inherited
Biological Process (BP) nitrogen compound metabolic process 1 Least Informative Inherited
Biological Process (BP) organic cyclic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) cellular aromatic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) cellular macromolecule metabolic process 1 Least Informative Inherited
Biological Process (BP) biosynthetic process 0.2799 Least Informative Inherited
Biological Process (BP) protein metabolic process 0.922 Least Informative Inherited
Biological Process (BP) localization 1 Least Informative Inherited
Biological Process (BP) carbohydrate metabolic process 1.989e-06 Moderately Informative Direct
Biological Process (BP) gene expression 6.082e-11 Moderately Informative Direct
Biological Process (BP) regulation of phosphate metabolic process 0.0002351 Moderately Informative Direct
Biological Process (BP) cellular macromolecule biosynthetic process 1.81e-11 Moderately Informative Direct
Biological Process (BP) regulation of catalytic activity 5.566e-05 Moderately Informative Direct
Biological Process (BP) cofactor metabolic process 0 Moderately Informative Direct
Biological Process (BP) nucleobase-containing small molecule metabolic process 0.0001849 Moderately Informative Direct
Biological Process (BP) regulation of nucleobase-containing compound metabolic process 0.02839 Moderately Informative Inherited
Biological Process (BP) positive regulation of molecular function 0.001556 Moderately Informative Inherited
Biological Process (BP) cellular catabolic process 1 Moderately Informative Inherited
Biological Process (BP) response to organic substance 0.9169 Moderately Informative Inherited
Biological Process (BP) response to oxygen-containing compound 0.154 Moderately Informative Inherited
Biological Process (BP) system process 0.278 Moderately Informative Inherited
Biological Process (BP) regulation of biological quality 1 Moderately Informative Inherited
Biological Process (BP) cell differentiation 0.2918 Moderately Informative Inherited
Biological Process (BP) nervous system development 0.04456 Moderately Informative Inherited
Biological Process (BP) response to abiotic stimulus 0.08341 Moderately Informative Inherited
Biological Process (BP) single-organism developmental process 1 Moderately Informative Inherited
Biological Process (BP) organ development 1 Moderately Informative Inherited
Biological Process (BP) cellular localization 0.5989 Moderately Informative Inherited
Biological Process (BP) cellular amino acid metabolic process 0.199 Moderately Informative Inherited
Biological Process (BP) phosphate-containing compound metabolic process 1 Moderately Informative Inherited
Biological Process (BP) organophosphate metabolic process 0.002982 Moderately Informative Inherited
Biological Process (BP) regulation of gene expression 0.7814 Moderately Informative Inherited
Biological Process (BP) regulation of macromolecule biosynthetic process 0.5377 Moderately Informative Inherited
Biological Process (BP) regulation of cellular biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of protein metabolic process 0.6977 Moderately Informative Inherited
Biological Process (BP) macromolecule localization 0.6299 Moderately Informative Inherited
Biological Process (BP) carbohydrate derivative metabolic process 0.3386 Moderately Informative Inherited
Biological Process (BP) reproduction 0.02373 Moderately Informative Inherited
Biological Process (BP) oxidoreduction coenzyme metabolic process 6.92e-05 Informative Direct
Biological Process (BP) central nervous system development 2.901e-05 Informative Direct
Biological Process (BP) regulation of nucleoside metabolic process 9.015e-12 Informative Direct
Biological Process (BP) carbohydrate catabolic process 1.587e-08 Informative Direct
Biological Process (BP) regulation of cellular catabolic process 5.384e-09 Informative Direct
Biological Process (BP) single organism reproductive process 1.089e-05 Informative Direct
Biological Process (BP) positive regulation of hydrolase activity 6.136e-07 Informative Direct
Biological Process (BP) pyridine-containing compound metabolic process 0 Informative Direct
Biological Process (BP) regulation of purine nucleotide metabolic process 9.785e-11 Informative Direct
Biological Process (BP) multicellular organismal reproductive process 0.1291 Informative Inherited
Biological Process (BP) cellular ketone metabolic process 0.001472 Informative Inherited
Biological Process (BP) vesicle-mediated transport 0.3946 Informative Inherited
Biological Process (BP) secretion by cell 0.034 Informative Inherited
Biological Process (BP) sexual reproduction 0.5051 Informative Inherited
Biological Process (BP) cellular process involved in reproduction 0.272 Informative Inherited
Biological Process (BP) cellular modified amino acid metabolic process 0.02159 Informative Inherited
Biological Process (BP) posttranscriptional regulation of gene expression 0.004292 Informative Inherited
Biological Process (BP) carbohydrate derivative catabolic process 0.2989 Informative Inherited
Biological Process (BP) hexose metabolic process 0.05464 Informative Inherited
Biological Process (BP) reproductive system development 0.001925 Informative Inherited
Biological Process (BP) developmental process involved in reproduction 0.00992 Informative Inherited
Biological Process (BP) amino sugar metabolic process 0 Highly Informative Direct
Biological Process (BP) translational initiation 0 Highly Informative Direct
Biological Process (BP) regulation of translation 4.839e-05 Highly Informative Direct
Biological Process (BP) folic acid-containing compound metabolic process 0.0004769 Highly Informative Direct
Biological Process (BP) gonad development 1.379e-07 Highly Informative Direct
Biological Process (BP) response to heat 2.798e-06 Highly Informative Direct
Biological Process (BP) response to carbohydrate stimulus 0.0003648 Highly Informative Direct
Biological Process (BP) glial cell differentiation 3.741e-15 Highly Informative Direct
Biological Process (BP) pentose metabolic process 0.0001802 Highly Informative Direct
Biological Process (BP) ovulation cycle process 1.659e-11 Highly Informative Direct
Biological Process (BP) regulation of membrane potential 3.276e-07 Highly Informative Direct
Biological Process (BP) nicotinamide nucleotide metabolic process 0 Highly Informative Direct
Biological Process (BP) development of primary female sexual characteristics 2.037e-10 Highly Informative Direct
Biological Process (BP) exocytosis 0.001318 Highly Informative Inherited
Biological Process (BP) fertilization 0.00476 Highly Informative Inherited
Molecular Function (MF) binding 1 Least Informative Inherited
Molecular Function (MF) hydrolase activity 1 Least Informative Inherited
Molecular Function (MF) transferase activity 0.6937 Least Informative Inherited
Molecular Function (MF) hydrolase activity, acting on ester bonds 5.342e-07 Moderately Informative Direct
Molecular Function (MF) isomerase activity 0 Moderately Informative Direct
Molecular Function (MF) enzyme regulator activity 8.535e-10 Moderately Informative Direct
Molecular Function (MF) anion binding 0.07564 Moderately Informative Inherited
Molecular Function (MF) oxidoreductase activity 1 Moderately Informative Inherited
Molecular Function (MF) nucleic acid binding 0.001511 Moderately Informative Inherited
Molecular Function (MF) RNA binding 6.319e-11 Informative Direct
Molecular Function (MF) oxidoreductase activity, acting on CH-OH group of donors 0.0002465 Informative Direct
Molecular Function (MF) intramolecular oxidoreductase activity 0 Informative Direct
Molecular Function (MF) GTPase regulator activity 1.185e-14 Informative Direct
Molecular Function (MF) purine ribonucleoside binding 0.000768 Informative Direct
Molecular Function (MF) purine ribonucleoside triphosphate binding 0.0008913 Informative Direct
Molecular Function (MF) nucleotide binding 0.4094 Informative Inherited
Molecular Function (MF) ligase activity, forming carbon-nitrogen bonds 0.001709 Informative Inherited
Molecular Function (MF) guanyl-nucleotide exchange factor activity 0 Highly Informative Direct
Molecular Function (MF) translation factor activity, nucleic acid binding 0 Highly Informative Direct
Molecular Function (MF) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 0.0001016 Highly Informative Direct
Molecular Function (MF) intramolecular oxidoreductase activity, interconverting aldoses and ketoses 0 Highly Informative Direct
Molecular Function (MF) deaminase activity 0 Highly Informative Direct
Molecular Function (MF) carboxylic ester hydrolase activity 1.211e-10 Highly Informative Direct
Molecular Function (MF) thiolester hydrolase activity 0.01472 Highly Informative Inherited
Cellular Component (CC) cytoplasmic part 1.847e-07 Least Informative Direct
Cellular Component (CC) protein complex 0.1427 Least Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 1 Least Informative Inherited

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Isomerases0Least InformativeDirect
Enzyme Commission (EC)Ligases1Least InformativeInherited
Enzyme Commission (EC)Acting on ester bonds1Least InformativeInherited
Enzyme Commission (EC)Intramolecular oxidoreductases0Moderately InformativeDirect
Enzyme Commission (EC)Carboxylic ester hydrolases1.442e-14Moderately InformativeDirect
Enzyme Commission (EC)Forming carbon-nitrogen bonds1Moderately InformativeInherited
Enzyme Commission (EC)Interconverting aldoses and ketoses, and related c0InformativeDirect
Enzyme Commission (EC)Thiolester hydrolases2.533e-05InformativeDirect
Enzyme Commission (EC)Cyclo-ligases0.01457InformativeInherited
Enzyme Commission (EC)In other compounds0Highly InformativeDirect

Document: EC annotation of SCOP domains

Human Phenotype (HP)

(show details) Document: HP annotation of SCOP domains

Worm Phenotype (WP)

(show details) Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details) Document: YP annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)genital system0Least InformativeDirect
Xenopus ANatomical entity (XAN)male organism0Least InformativeDirect
Xenopus ANatomical entity (XAN)viscus0Least InformativeDirect
Xenopus ANatomical entity (XAN)gonad0Least InformativeDirect

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant structure DEvelopment stage (PDE)LP.04 four leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.06 six leaves visible stage0Least InformativeDirect

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Hydrolases0.0001825Least InformativeDirect
Enzyme Commission (EC)Oxidoreductases1Least InformativeInherited
Enzyme Commission (EC)Lyases1Least InformativeInherited
Enzyme Commission (EC)Acting on carbon-nitrogen bonds, other than peptide bonds0Moderately InformativeDirect
Enzyme Commission (EC)Isomerases0Moderately InformativeDirect
Enzyme Commission (EC)Acting on the CH-OH group of donors1Moderately InformativeInherited
Enzyme Commission (EC)Carbon-carbon lyases1Moderately InformativeInherited
Enzyme Commission (EC)Ligases1Moderately InformativeInherited
Enzyme Commission (EC)Intramolecular oxidoreductases0InformativeDirect
Enzyme Commission (EC)Carboxylic ester hydrolases8.015e-15InformativeDirect
Enzyme Commission (EC)With NAD(+) or NADP(+) as acceptor1InformativeInherited
Enzyme Commission (EC)Interconverting aldoses and ketoses, and related compounds0Highly InformativeDirect
Enzyme Commission (EC)Cyclo-ligases0.0001121Highly InformativeDirect
Enzyme Commission (EC)Oxo-acid-lyases0.3611Highly InformativeInherited

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processAmino-acid biosynthesis0Moderately InformativeDirect
Biological processCarbohydrate metabolism0Moderately InformativeDirect
Biological processMethionine biosynthesis0Highly InformativeDirect
Post-translational modificationHydrolase1.392e-06Least InformativeDirect
Post-translational modificationIsomerase0Moderately InformativeDirect
Post-translational modificationRepressor1.92e-06Moderately InformativeDirect
Post-translational modificationInitiation factor1.542e-08InformativeDirect

Document: KW annotation of SCOP domains

UniProtKB UniPathway (UP)

(show details)
UP termFDR (all)SDUP levelAnnotation (direct or inherited)
UniPathway (UP)carbohydrate metabolism0Moderately InformativeDirect
UniPathway (UP)fatty acid metabolism0.1959Moderately InformativeInherited
UniPathway (UP)pentose phosphate pathway0InformativeDirect
UniPathway (UP)one-carbon metabolism1.109e-05InformativeDirect
UniPathway (UP)tetrahydrofolate metabolism0.0004167InformativeDirect
UniPathway (UP)tetrahydrofolate interconversion7.426e-08Highly InformativeDirect

Document: UP annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Human Phenotype (HP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 32 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a NagB/RpiA/CoA transferase-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 32 hidden Markov models representing the NagB/RpiA/CoA transferase-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Human Phenotype (HP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) · Internal database links ]