SUPERFAMILY 1.75 HMM library and genome assignments server

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Translation initiation factor 2 beta, aIF2beta, N-terminal domain superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   Ribosome binding domain-like [ 100965] (2)
Superfamily:   Translation initiation factor 2 beta, aIF2beta, N-terminal domain [ 100966]
Families:   Translation initiation factor 2 beta, aIF2beta, N-terminal domain [ 100967]


Superfamily statistics
Genomes (667) Uniprot 2017_06 genome PDB chains (SCOP 1.75)
Domains 1,596 4,051 2
Proteins 1,591 4,045 2


Functional annotation
General category Information
Detailed category Translation

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) biosynthetic process 0.00001536 Least Informative Direct
Biological Process (BP) cellular nitrogen compound metabolic process 0.000054 Least Informative Direct
Biological Process (BP) organonitrogen compound metabolic process 0.001136 Least Informative Inherited
Biological Process (BP) primary metabolic process 0.03006 Least Informative Inherited
Biological Process (BP) macromolecule metabolic process 0.002162 Least Informative Inherited
Biological Process (BP) peptide metabolic process 0.0000000000001817 Moderately Informative Direct
Biological Process (BP) gene expression 0.00000001185 Moderately Informative Direct
Biological Process (BP) cellular macromolecule biosynthetic process 0.00000000271 Moderately Informative Direct
Biological Process (BP) amide biosynthetic process 0.0000000000001264 Moderately Informative Direct
Biological Process (BP) translational initiation 0 Highly Informative Direct
Molecular Function (MF) binding 0.002778 Least Informative Inherited
Molecular Function (MF) nucleic acid binding 0.000000000005002 Moderately Informative Direct
Molecular Function (MF) RNA binding 0 Informative Direct
Molecular Function (MF) translation factor activity, RNA binding 0 Highly Informative Direct
Cellular Component (CC) cytoplasmic part 0.01074 Least Informative Inherited

Document: GO annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processProtein biosynthesis0InformativeDirect
DomainZinc-finger0.00000002276Moderately InformativeDirect
Molecular functionNucleotide-binding0.9941Least InformativeInherited
Molecular functionGTP-binding0.00000005318InformativeDirect
Post-translational modificationInitiation factor0InformativeDirect
Post-translational modificationPhosphoprotein0.00008922Least InformativeDirect
Post-translational modificationIsopeptide bond0.0000001113Moderately InformativeDirect
Post-translational modificationUbl conjugation0.000002669Moderately InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 2 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Translation initiation factor 2 beta, aIF2beta, N-terminal domain domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 2 hidden Markov models representing the Translation initiation factor 2 beta, aIF2beta, N-terminal domain superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) · Internal database links ]