SUPERFAMILY 1.75 HMM library and genome assignments server


Translation initiation factor 2 beta, aIF2beta, N-terminal domain superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   Ribosome binding domain-like [ 100965] (2)
Superfamily:   Translation initiation factor 2 beta, aIF2beta, N-terminal domain [ 100966]
Families:   Translation initiation factor 2 beta, aIF2beta, N-terminal domain [ 100967]


Superfamily statistics
Genomes (573) Uniprot 2013_05 PDB chains (SCOP 1.75)
Domains 1,391 1,320 2
Proteins 1,387 1,319 2


Functional annotation
General category Information
Detailed category Translation

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) protein metabolic process 0.0002452 Least Informative Direct
Biological Process (BP) biosynthetic process 0.0005997 Least Informative Direct
Biological Process (BP) cellular macromolecule metabolic process 0.005441 Least Informative Inherited
Biological Process (BP) single-organism cellular process 0.5657 Least Informative Inherited
Biological Process (BP) cellular macromolecule biosynthetic process 1.057e-06 Moderately Informative Direct
Biological Process (BP) gene expression 1.045e-05 Moderately Informative Direct
Biological Process (BP) translational initiation 0 Highly Informative Direct
Molecular Function (MF) binding 0.01361 Least Informative Inherited
Molecular Function (MF) heterocyclic compound binding 5.48e-08 Moderately Informative Direct
Molecular Function (MF) organic cyclic compound binding 6.975e-08 Moderately Informative Direct
Molecular Function (MF) RNA binding 1.562e-15 Informative Direct
Molecular Function (MF) translation factor activity, nucleic acid binding 6.356e-11 Highly Informative Direct
Cellular Component (CC) cytoplasmic part 0.01627 Least Informative Inherited
Cellular Component (CC) protein complex 0.4004 Least Informative Inherited

Document: GO annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)plant cell0Least InformativeDirect
Plant ANatomical entity (PAN)microsporophyll0Least InformativeDirect
Plant ANatomical entity (PAN)plant sperm cell0InformativeDirect

Document: AP annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processInitiation factor0InformativeDirect
Molecular functionMetal-binding0.9049Least InformativeInherited
Molecular functionNucleotide-binding0.9371Least InformativeInherited
Molecular functionZinc-finger1.817e-08Moderately InformativeDirect
Molecular functionGTP-binding6.008e-08InformativeDirect
Post-translational modificationPhosphoprotein0.0003937Least InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Arabidopsis Plant Ontology (AP) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 2 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Translation initiation factor 2 beta, aIF2beta, N-terminal domain domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 2 hidden Markov models representing the Translation initiation factor 2 beta, aIF2beta, N-terminal domain superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Arabidopsis Plant Ontology (AP) · UniProtKB KeyWords (KW) · Internal database links ]