SUPERFAMILY 1.75 HMM library and genome assignments server

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Translation initiation factor 2 beta, aIF2beta, N-terminal domain superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   Ribosome binding domain-like [ 100965] (2)
Superfamily:   Translation initiation factor 2 beta, aIF2beta, N-terminal domain [ 100966]
Families:   Translation initiation factor 2 beta, aIF2beta, N-terminal domain [ 100967]


Superfamily statistics
Genomes (658) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 1,551 1,903 2
Proteins 1,546 1,902 2


Functional annotation
General category Information
Detailed category Translation

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) biosynthetic process 0.00005258 Least Informative Direct
Biological Process (BP) protein metabolic process 0.00001128 Least Informative Direct
Biological Process (BP) cellular macromolecule metabolic process 0.0004747 Least Informative Direct
Biological Process (BP) gene expression 0.000004322 Moderately Informative Direct
Biological Process (BP) cellular macromolecule biosynthetic process 0.0000004121 Moderately Informative Direct
Biological Process (BP) translational initiation 0 Highly Informative Direct
Molecular Function (MF) binding 0.001445 Least Informative Inherited
Molecular Function (MF) nucleic acid binding 0.000000000007838 Moderately Informative Direct
Molecular Function (MF) RNA binding 0 Informative Direct
Molecular Function (MF) translation factor activity, nucleic acid binding 0 Highly Informative Direct
Cellular Component (CC) protein complex 0.5244 Least Informative Inherited
Cellular Component (CC) cytoplasmic part 0.02618 Least Informative Inherited

Document: GO annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)whole plant0Least InformativeDirect
Plant ANatomical entity (PAN)microsporophyll0Least InformativeDirect
Plant ANatomical entity (PAN)gamete0InformativeDirect

Document: AP annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processProtein biosynthesis0InformativeDirect
DomainZinc-finger0.00000002283Moderately InformativeDirect
Molecular functionNucleotide-binding0.9365Least InformativeInherited
Molecular functionGTP-binding0.00000005931InformativeDirect
Post-translational modificationInitiation factor0InformativeDirect
Post-translational modificationPhosphoprotein0.0002669Least InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Arabidopsis Plant Ontology (AP) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 2 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Translation initiation factor 2 beta, aIF2beta, N-terminal domain domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 2 hidden Markov models representing the Translation initiation factor 2 beta, aIF2beta, N-terminal domain superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Arabidopsis Plant Ontology (AP) · UniProtKB KeyWords (KW) · Internal database links ]