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L27 domain superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All alpha proteins [ 46456] (284)
Fold:   L27 domain [ 101287]
Superfamily:   L27 domain [ 101288]
Families:   L27 domain [ 101289] (5)


Superfamily statistics
Genomes (147) Uniprot 2017_06 genome PDB chains (SCOP 1.75)
Domains 1,744 4,467 10
Proteins 1,534 3,821 10


Functional annotation
General category Information
Detailed category Translation

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) cellular component organization or biogenesis 0.00000000001914 Least Informative Direct
Biological Process (BP) single-organism cellular process 0.0000001753 Least Informative Direct
Biological Process (BP) biological regulation 0.000009176 Least Informative Direct
Biological Process (BP) multicellular organismal process 0.0002766 Least Informative Direct
Biological Process (BP) regulation of biological quality 0.000000003806 Moderately Informative Direct
Biological Process (BP) cellular component assembly 0.00006846 Moderately Informative Direct
Biological Process (BP) regulation of cellular component organization 0.0006281 Moderately Informative Direct
Biological Process (BP) single organism signaling 0.00989 Moderately Informative Inherited
Biological Process (BP) anatomical structure morphogenesis 0.01568 Moderately Informative Inherited
Biological Process (BP) regulation of developmental process 0.001047 Moderately Informative Inherited
Biological Process (BP) single-organism transport 0.3633 Moderately Informative Inherited
Biological Process (BP) negative regulation of cellular process 1 Moderately Informative Inherited
Biological Process (BP) organelle organization 1 Moderately Informative Inherited
Biological Process (BP) cell communication 0.01477 Moderately Informative Inherited
Biological Process (BP) regulation of multicellular organismal process 0.003384 Moderately Informative Inherited
Biological Process (BP) macromolecule localization 0.01198 Moderately Informative Inherited
Biological Process (BP) cellular localization 0.005709 Moderately Informative Inherited
Biological Process (BP) regulation of cellular component biogenesis 0.00000009185 Informative Direct
Biological Process (BP) growth 0.0000013 Informative Direct
Biological Process (BP) regulation of growth 0.0000161 Informative Direct
Biological Process (BP) regulation of nervous system development 0.00164 Informative Inherited
Biological Process (BP) regulation of cell cycle 0.01642 Informative Inherited
Biological Process (BP) regulation of anatomical structure size 0.001057 Informative Inherited
Biological Process (BP) secretion by cell 0.001306 Informative Inherited
Biological Process (BP) actin cytoskeleton organization 0.007018 Informative Inherited
Biological Process (BP) supramolecular fiber organization 0.02124 Informative Inherited
Biological Process (BP) developmental growth involved in morphogenesis 0.0000004165 Highly Informative Direct
Biological Process (BP) cell-cell signaling 0.000002901 Highly Informative Direct
Biological Process (BP) establishment or maintenance of cell polarity 0.00000441 Highly Informative Direct
Biological Process (BP) biological adhesion 0.00000452 Highly Informative Direct
Biological Process (BP) regulation of developmental growth 0.000006839 Highly Informative Direct
Biological Process (BP) negative regulation of mitotic cell cycle 0.000008685 Highly Informative Direct
Biological Process (BP) actin filament organization 0.0000135 Highly Informative Direct
Biological Process (BP) regulation of neurotransmitter levels 0.0003742 Highly Informative Direct
Biological Process (BP) protein localization to membrane 0.0005912 Highly Informative Direct
Biological Process (BP) cell proliferation 0.001611 Highly Informative Inherited
Molecular Function (MF) binding 0.0000001443 Least Informative Direct
Molecular Function (MF) transferase activity 0.2191 Least Informative Inherited
Molecular Function (MF) transferase activity, transferring phosphorus-containing groups 0.004212 Moderately Informative Inherited
Molecular Function (MF) enzyme binding 0.3488 Informative Inherited
Molecular Function (MF) kinase activity 0.001109 Informative Inherited
Molecular Function (MF) phosphotransferase activity, phosphate group as acceptor 0.00000000000007015 Highly Informative Direct
Molecular Function (MF) nucleobase-containing compound kinase activity 0.000000000000117 Highly Informative Direct
Molecular Function (MF) protein domain specific binding 0.0000000000006045 Highly Informative Direct
Molecular Function (MF) kinase binding 0.00004326 Highly Informative Direct
Cellular Component (CC) membrane 0.000000000000817 Least Informative Direct
Cellular Component (CC) cytoplasmic part 0.9786 Least Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) plasma membrane 0 Moderately Informative Direct
Cellular Component (CC) cell projection 0.0002622 Moderately Informative Direct
Cellular Component (CC) extracellular region part 0.01247 Moderately Informative Inherited
Cellular Component (CC) vesicle 0.008127 Moderately Informative Inherited
Cellular Component (CC) plasma membrane bounded cell projection part 0.000000001751 Informative Direct
Cellular Component (CC) plasma membrane region 0.000000008116 Informative Direct
Cellular Component (CC) extracellular organelle 0.0003514 Informative Direct
Cellular Component (CC) extracellular space 1 Informative Inherited
Cellular Component (CC) neuron projection 0.0307 Informative Inherited
Cellular Component (CC) cell-cell junction 0.00001283 Highly Informative Direct
Cellular Component (CC) extracellular exosome 0.0002862 Highly Informative Direct
Cellular Component (CC) presynapse 0.001465 Highly Informative Inherited

Document: GO annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTransport0.009715Least InformativeInherited
Biological processProtein transport0.000000002121Moderately InformativeDirect
Biological processExocytosis0Highly InformativeDirect
Cellular componentMembrane0Least InformativeDirect
Cellular componentCell junction0Moderately InformativeDirect
Cellular componentCell projection0.0000006452Moderately InformativeDirect
Cellular componentEndoplasmic reticulum0.0005849Moderately InformativeDirect
Cellular componentSynapse0.9242InformativeInherited
Cellular componentPostsynaptic cell membrane0Highly InformativeDirect
Cellular componentTight junction0Highly InformativeDirect
Cellular componentSynaptosome0.000003759Highly InformativeDirect
DomainRepeat0Least InformativeDirect
DomainSH3 domain0InformativeDirect
Post-translational modificationPhosphoprotein0.00000000006493Least InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 9 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a L27 domain domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 9 hidden Markov models representing the L27 domain superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) · Internal database links ]