SUPERFAMILY 1.75 HMM library and genome assignments server

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Sensory domain-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   Profilin-like [ 55769] (10)
Superfamily:   Sensory domain-like [ 103190] (3)
Families:   Sensory domain of two-component sensor kinase [ 103191] (2)
  YkuI C-terminal domain-like [ 143732] (2)
  LuxQ-periplasmic domain-like [ 160679]

Superfamily statistics
Genomes (1,671) Uniprot 2017_06 genome PDB chains (SCOP 1.75)
Domains 7,479 46,297 10
Proteins 7,205 44,649 9

Functional annotation
General category General
Detailed category Small molecule binding

Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) response to stimulus 0.0000000000007969 Least Informative Direct
Biological Process (BP) biological regulation 0.6204 Least Informative Inherited
Biological Process (BP) macromolecule metabolic process 0.8296 Least Informative Inherited
Biological Process (BP) primary metabolic process 1 Least Informative Inherited
Biological Process (BP) organonitrogen compound metabolic process 0.7441 Least Informative Inherited
Biological Process (BP) cell communication 0.000001697 Moderately Informative Direct
Biological Process (BP) response to external stimulus 0.00008196 Moderately Informative Direct
Biological Process (BP) single organism signaling 0.0000004829 Moderately Informative Direct
Biological Process (BP) cellular protein modification process 0.07733 Moderately Informative Inherited
Biological Process (BP) intracellular signal transduction 0.000001116 Informative Direct
Biological Process (BP) locomotion 0 Informative Direct
Biological Process (BP) phosphorylation 0.002571 Informative Inherited
Molecular Function (MF) transferase activity 0.000007482 Least Informative Direct
Molecular Function (MF) transferase activity, transferring phosphorus-containing groups 0.0000000005264 Moderately Informative Direct
Molecular Function (MF) signal transducer activity 0 Informative Direct
Molecular Function (MF) kinase activity 0.00000000003402 Informative Direct
Molecular Function (MF) phosphotransferase activity, alcohol group as acceptor 0.000000000006946 Informative Direct
Molecular Function (MF) molecular transducer activity 0 Informative Direct
Molecular Function (MF) protein kinase activity 0.0000000000001039 Highly Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Protein-histidine kinases0InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processChemotaxis0InformativeDirect
Biological processTwo-component regulatory system0Highly InformativeDirect
Cellular componentMembrane0Least InformativeDirect
Cellular componentCell membrane0.00000000002265Moderately InformativeDirect
DomainTransmembrane0Least InformativeDirect
Molecular functionNucleotide-binding0.0000000003495Least InformativeDirect
Post-translational modificationTransferase0.0000000006174Least InformativeDirect
Post-translational modificationHydrolase1Least InformativeInherited
Post-translational modificationKinase0Moderately InformativeDirect
Post-translational modificationProtein phosphatase0.00000001553InformativeDirect
Post-translational modificationMethylation0.000005066Moderately InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.

Alignments of sequences to 6 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.

Browse and view proteins in genomes which have different domain combinations including a Sensory domain-like domain.

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.

Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 6 hidden Markov models representing the Sensory domain-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · Internal database links ]