SUPERFAMILY 1.75 HMM library and genome assignments server

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TSP type-3 repeat superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Small proteins [ 56992] (90)
Fold:   TSP type-3 repeat [ 103646]
Superfamily:   TSP type-3 repeat [ 103647]
Families:   TSP type-3 repeat [ 103648]


Superfamily statistics
Genomes (624) Uniprot 2017_06 genome PDB chains (SCOP 1.75)
Domains 2,928 15,389 1
Proteins 1,542 10,073 1


Functional annotation
General category Processes_EC
Detailed category Cell adhesion

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) biological regulation 0.3063 Least Informative Inherited
Biological Process (BP) multicellular organismal process 0.01822 Least Informative Inherited
Biological Process (BP) response to stimulus 0.3473 Least Informative Inherited
Biological Process (BP) regulation of developmental process 0.0001986 Moderately Informative Direct
Biological Process (BP) regulation of multicellular organismal process 0.0000005988 Moderately Informative Direct
Biological Process (BP) cellular response to stress 0.001909 Moderately Informative Inherited
Biological Process (BP) behavior 0.000002271 Informative Direct
Biological Process (BP) regulation of anatomical structure morphogenesis 0.00000001554 Informative Direct
Biological Process (BP) negative regulation of multicellular organismal process 0.00001222 Informative Direct
Biological Process (BP) biological adhesion 0.0000002134 Highly Informative Direct
Biological Process (BP) response to endoplasmic reticulum stress 0.00000000002546 Highly Informative Direct
Biological Process (BP) single-organism behavior 0.00000002224 Highly Informative Direct
Molecular Function (MF) binding 0.004835 Least Informative Inherited
Molecular Function (MF) anion binding 0.00000002011 Moderately Informative Direct
Molecular Function (MF) carbohydrate derivative binding 0.0000000242 Moderately Informative Direct
Molecular Function (MF) sulfur compound binding 0.000000000000001615 Informative Direct
Molecular Function (MF) heparin binding 0 Highly Informative Direct
Cellular Component (CC) intracellular membrane-bounded organelle 0.5213 Least Informative Inherited
Cellular Component (CC) cytoplasmic part 0.06872 Least Informative Inherited
Cellular Component (CC) endomembrane system 0.000003222 Moderately Informative Direct
Cellular Component (CC) extracellular region part 0 Moderately Informative Direct
Cellular Component (CC) sarcoplasm 0 Highly Informative Direct

Document: GO annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processCell adhesion0InformativeDirect
Biological processUnfolded protein response0Highly InformativeDirect
Cellular componentEndoplasmic reticulum0.0000000000001125Moderately InformativeDirect
Cellular componentSecreted0.000000003198Moderately InformativeDirect
Cellular componentExtracellular matrix0.000000000000004523InformativeDirect
Cellular componentSarcoplasmic reticulum0Highly InformativeDirect
Coding sequence diversityPolymorphism0.0004864Moderately InformativeDirect
DomainSignal0.000000000000001243Least InformativeDirect
DomainRepeat0.000000000003645Least InformativeDirect
DomainEGF-like domain0InformativeDirect
Molecular functionCalcium0Moderately InformativeDirect
Post-translational modificationHeparin-binding0InformativeDirect
Post-translational modificationMitogen2.221e-16Highly InformativeDirect
Post-translational modificationGrowth factor0.000000000001133Highly InformativeDirect
Post-translational modificationDisulfide bond0Least InformativeDirect
Post-translational modificationGlycoprotein0.00000000001869Least InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 1 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a TSP type-3 repeat domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 1 hidden Markov models representing the TSP type-3 repeat superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) · Internal database links ]