SUPERFAMILY 1.75 HMM library and genome assignments server

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GTF2I-like repeat superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   GTF2I-like repeat [ 117772]
Superfamily:   GTF2I-like repeat [ 117773]
Families:   GTF2I-like repeat [ 117774]

Superfamily statistics
Genomes (67) Uniprot 2017_06 genome PDB chains (SCOP 1.75)
Domains 945 2,060 1
Proteins 235 516 1

Functional annotation
General category Regulation
Detailed category DNA-binding

Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Molecular Function (MF) transcription regulator activity 0.0000005664 Informative Direct
Molecular Function (MF) DNA binding transcription factor activity 0.0000001416 Highly Informative Direct
Cellular Component (CC) intracellular membrane-bounded organelle 0.0009079 Least Informative Direct
Cellular Component (CC) intracellular organelle part 0.2823 Least Informative Inherited
Cellular Component (CC) nuclear part 0.05934 Moderately Informative Inherited
Cellular Component (CC) intracellular organelle lumen 0.008166 Moderately Informative Inherited

Document: GO annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTranscription regulation0Moderately InformativeDirect
Cellular componentNucleus0Least InformativeDirect
Coding sequence diversityAlternative splicing0.00000004873Least InformativeDirect
DomainRepeat0Least InformativeDirect
Post-translational modificationDNA-binding0Moderately InformativeDirect
Post-translational modificationPhosphoprotein0.00003607Least InformativeDirect
Post-translational modificationIsopeptide bond0.0000000001129Moderately InformativeDirect
Post-translational modificationUbl conjugation0.000000001413Moderately InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.

Alignments of sequences to 1 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.

Browse and view proteins in genomes which have different domain combinations including a GTF2I-like repeat domain.

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.

Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 1 hidden Markov models representing the GTF2I-like repeat superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) · Internal database links ]