SUPERFAMILY 1.75 HMM library and genome assignments server

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Fe-S cluster assembly (FSCA) domain-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   Alpha-lytic protease prodomain-like [ 54805] (10)
Superfamily:   Fe-S cluster assembly (FSCA) domain-like [ 117916] (2)
Families:   NifU C-terminal domain-like [ 117917] (3)
  PaaD-like [ 117922] (2)

Superfamily statistics
Genomes (2,975) Uniprot 2017_06 genome PDB chains (SCOP 1.75)
Domains 7,951 39,591 5
Proteins 7,695 39,204 5

Functional annotation
General category Processes_IC
Detailed category Ion metabolism and transport

Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) biosynthetic process 0.2916 Least Informative Inherited
Biological Process (BP) cellular component organization or biogenesis 0.7938 Least Informative Inherited
Biological Process (BP) sulfur compound metabolic process 0.0000007119 Moderately Informative Direct
Biological Process (BP) cofactor metabolic process 0.000004878 Moderately Informative Direct
Biological Process (BP) cellular component assembly 0.006113 Moderately Informative Inherited
Biological Process (BP) iron-sulfur cluster assembly 0.000000000000001925 Highly Informative Direct

Document: GO annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processNitrogen fixation0InformativeDirect
Biological processChromosome partition0Highly InformativeDirect
Cellular componentMitochondrion0.0000092Moderately InformativeDirect
DomainTransit peptide0.00000000000009941Moderately InformativeDirect
Molecular functionMetal-binding0Least InformativeDirect
Molecular functionIron0Moderately InformativeDirect
Molecular functionIron-sulfur0Moderately InformativeDirect
Molecular function4Fe-4S0InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.

Alignments of sequences to 5 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.

Browse and view proteins in genomes which have different domain combinations including a Fe-S cluster assembly (FSCA) domain-like domain.

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.

Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 5 hidden Markov models representing the Fe-S cluster assembly (FSCA) domain-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) · Internal database links ]