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Proton glutamate symport protein superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Membrane and cell surface proteins and peptides [ 56835] (58)
Fold:   Proton glutamate symport protein [ 118214]
Superfamily:   Proton glutamate symport protein [ 118215]
Families:   Proton glutamate symport protein [ 118216]


Superfamily statistics
Genomes (2,171) Uniprot 2017_06 genome PDB chains (SCOP 1.75)
Domains 6,668 36,757 1
Proteins 6,588 36,589 1


Functional annotation
General category Processes_IC
Detailed category Transport

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)single-organism cellular process11Least InformativeInherited
Biological Process (BP)cellular component organization or biogenesis0.66380.997Least InformativeInherited
Biological Process (BP)multicellular organismal process0.18721Least InformativeInherited
Biological Process (BP)ion transport00Moderately InformativeDirect
Biological Process (BP)single-organism transport00Moderately InformativeDirect
Biological Process (BP)organic substance transport00Moderately InformativeDirect
Biological Process (BP)nitrogen compound transport0.00000027230Moderately InformativeDirect
Biological Process (BP)single organism signaling0.54831Moderately InformativeInherited
Biological Process (BP)cellular component assembly0.10070.07709Moderately InformativeInherited
Biological Process (BP)macromolecular complex subunit organization0.039980.009284Moderately InformativeInherited
Biological Process (BP)protein complex biogenesis0.013740.0006715Moderately InformativeInherited
Biological Process (BP)cell communication0.074060.2003Moderately InformativeInherited
Biological Process (BP)anion transport00InformativeDirect
Biological Process (BP)behavior0.000013030.00002547InformativeDirect
Biological Process (BP)organic acid transport00InformativeDirect
Biological Process (BP)transmembrane transport0.11030.000001751InformativeInherited
Biological Process (BP)protein oligomerization0.0021030.00001197InformativeInherited
Biological Process (BP)dicarboxylic acid transport0.00000000011750.000000000000001925Highly InformativeDirect
Biological Process (BP)amino acid transport0.000000000000006150Highly InformativeDirect
Biological Process (BP)cell-cell signaling0.000020830.00004491Highly InformativeDirect
Biological Process (BP)single-organism behavior0.000010840.00006696Highly InformativeDirect
Biological Process (BP)sulfur compound transport0.0000087450.000000001992Highly InformativeDirect
Biological Process (BP)import into cell0.00000028850Highly InformativeDirect
Biological Process (BP)anion transmembrane transport0.066040.0000001902Highly InformativeInherited
Biological Process (BP)organic acid transmembrane transport0.0071240Highly InformativeInherited
Biological Process (BP)locomotory behavior0.00000001640.005613Highly InformativeInherited
Molecular Function (MF)transporter activity00Moderately InformativeDirect
Molecular Function (MF)monovalent inorganic cation transmembrane transporter activity00InformativeDirect
Molecular Function (MF)active ion transmembrane transporter activity0.00061840.000000001419InformativeDirect
Molecular Function (MF)metal ion transmembrane transporter activity0.00022390.00005282InformativeDirect
Molecular Function (MF)anion transmembrane transporter activity0.052830.0000000000001728InformativeInherited
Molecular Function (MF)sodium ion transmembrane transporter activity0.000000066430Highly InformativeDirect
Molecular Function (MF)secondary active transmembrane transporter activity00Highly InformativeDirect
Molecular Function (MF)sulfur compound transmembrane transporter activity0.000022650.000000005899Highly InformativeDirect
Molecular Function (MF)amino acid transmembrane transporter activity0.053280.000002845Highly InformativeInherited
Molecular Function (MF)inorganic anion transmembrane transporter activity0.065111Highly InformativeInherited
Cellular Component (CC)membrane0.00031860.000000000003998Least InformativeDirect
Cellular Component (CC)non-membrane-bounded organelle0.096410.2795Least InformativeInherited
Cellular Component (CC)plasma membrane0.00000054410Moderately InformativeDirect
Cellular Component (CC)intrinsic component of membrane0.0000000084320.00000000000000156Moderately InformativeDirect
Cellular Component (CC)cytoskeleton0.0023080.003661Moderately InformativeInherited
Cellular Component (CC)apical part of cell0.00000051140.0002201InformativeDirect
Cellular Component (CC)intermediate filament cytoskeleton0.00000000048910.000000000004037Highly InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) single-organism cellular process 1 Least Informative Inherited
Biological Process (BP) multicellular organismal process 1 Least Informative Inherited
Biological Process (BP) cellular component organization or biogenesis 0.997 Least Informative Inherited
Biological Process (BP) ion transport 0 Moderately Informative Direct
Biological Process (BP) single-organism transport 0 Moderately Informative Direct
Biological Process (BP) protein complex biogenesis 0.0006715 Moderately Informative Direct
Biological Process (BP) organic substance transport 0 Moderately Informative Direct
Biological Process (BP) nitrogen compound transport 0 Moderately Informative Direct
Biological Process (BP) single organism signaling 1 Moderately Informative Inherited
Biological Process (BP) cell communication 0.2003 Moderately Informative Inherited
Biological Process (BP) macromolecular complex subunit organization 0.009284 Moderately Informative Inherited
Biological Process (BP) cellular component assembly 0.07709 Moderately Informative Inherited
Biological Process (BP) anion transport 0 Informative Direct
Biological Process (BP) behavior 0.00002547 Informative Direct
Biological Process (BP) organic acid transport 0 Informative Direct
Biological Process (BP) secretion by cell 0.000004738 Informative Direct
Biological Process (BP) protein oligomerization 0.00001197 Informative Direct
Biological Process (BP) transmembrane transport 0.000001751 Informative Direct
Biological Process (BP) metal ion transport 1 Informative Inherited
Biological Process (BP) dicarboxylic acid transport 0.000000000000001925 Highly Informative Direct
Biological Process (BP) amino acid transport 0 Highly Informative Direct
Biological Process (BP) cell-cell signaling 0.00004491 Highly Informative Direct
Biological Process (BP) single-organism behavior 0.00006696 Highly Informative Direct
Biological Process (BP) sulfur compound transport 0.000000001992 Highly Informative Direct
Biological Process (BP) anion transmembrane transport 0.0000001902 Highly Informative Direct
Biological Process (BP) import into cell 0 Highly Informative Direct
Biological Process (BP) organic acid transmembrane transport 0 Highly Informative Direct
Biological Process (BP) inorganic cation transmembrane transport 1 Highly Informative Inherited
Biological Process (BP) locomotory behavior 0.005613 Highly Informative Inherited
Molecular Function (MF) transporter activity 0 Moderately Informative Direct
Molecular Function (MF) anion transmembrane transporter activity 0.0000000000001728 Informative Direct
Molecular Function (MF) monovalent inorganic cation transmembrane transporter activity 0 Informative Direct
Molecular Function (MF) active ion transmembrane transporter activity 0.000000001419 Informative Direct
Molecular Function (MF) metal ion transmembrane transporter activity 0.00005282 Informative Direct
Molecular Function (MF) sodium ion transmembrane transporter activity 0 Highly Informative Direct
Molecular Function (MF) amino acid transmembrane transporter activity 0.000002845 Highly Informative Direct
Molecular Function (MF) secondary active transmembrane transporter activity 0 Highly Informative Direct
Molecular Function (MF) sulfur compound transmembrane transporter activity 0.000000005899 Highly Informative Direct
Molecular Function (MF) inorganic anion transmembrane transporter activity 1 Highly Informative Inherited
Cellular Component (CC) membrane 0.000000000003998 Least Informative Direct
Cellular Component (CC) non-membrane-bounded organelle 0.2795 Least Informative Inherited
Cellular Component (CC) plasma membrane 0 Moderately Informative Direct
Cellular Component (CC) intrinsic component of membrane 0.00000000000000156 Moderately Informative Direct
Cellular Component (CC) cytoskeleton 0.003661 Moderately Informative Inherited
Cellular Component (CC) cell projection 0.01014 Moderately Informative Inherited
Cellular Component (CC) neuron projection 0.0002761 Informative Direct
Cellular Component (CC) apical part of cell 0.0002201 Informative Direct
Cellular Component (CC) intrinsic component of plasma membrane 0.000001563 Highly Informative Direct
Cellular Component (CC) intermediate filament cytoskeleton 0.000000000004037 Highly Informative Direct

Document: GO annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTransport0Least InformativeDirect
Biological processAmino-acid transport0Highly InformativeDirect
Cellular componentMembrane0Least InformativeDirect
Cellular componentCell membrane0Moderately InformativeDirect
Cellular componentCell inner membrane0InformativeDirect
DomainTransmembrane0Least InformativeDirect
Molecular functionChloride0InformativeDirect
Molecular functionSodium0InformativeDirect
Molecular functionPotassium0.000000000004743InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 1 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Proton glutamate symport protein domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 1 hidden Markov models representing the Proton glutamate symport protein superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) · Internal database links ]