SUPERFAMILY 1.75 HMM library and genome assignments server

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SOCS box-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All alpha proteins [ 46456] (284)
Fold:   SOCS box-like [ 158234]
Superfamily:   SOCS box-like [ 158235]
Families:   SOCS box-like [ 158236] (2)


Superfamily statistics
Genomes (144) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 2,851 7,179 2
Proteins 2,850 7,177 2


Functional annotation
Document:
Function annotation of SCOP domain superfamilies

Disease Ontology (DO)

(show details)
DO termFDR (all)SDDO levelAnnotation (direct or inherited)
Disease Ontology (DO)organ system cancer0.2607Least InformativeInherited
Disease Ontology (DO)disease by infectious agent0.00459Moderately InformativeInherited
Disease Ontology (DO)hematologic cancer0.07587Moderately InformativeInherited
Disease Ontology (DO)primary bacterial infectious disease0.002101InformativeInherited
Disease Ontology (DO)myeloid leukemia0.1328InformativeInherited
Disease Ontology (DO)in situ carcinoma0.00003823Highly InformativeDirect
Disease Ontology (DO)tuberculosis0.0006086Highly InformativeDirect

Document: DO annotation of SCOP domains

Fly Anatomy (FA)

(show details) Document: FA annotation of SCOP domains

Zebrafish Anatomy (ZA)

(show details) Document: ZA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)tail region0.001445Moderately InformativeInherited
Xenopus ANatomical entity (XAN)tail0.0005778InformativeDirect

Document: XA annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Disease Ontology (DO) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 2 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a SOCS box-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 2 hidden Markov models representing the SOCS box-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Disease Ontology (DO) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Internal database links ]